[ { "title": "Prolactin-induced proliferation of Nb2 cells involves tyrosine phosphorylation of the prolactin receptor and its associated tyrosine kinase JAK2.", "journal": "The Journal of biological chemistry", "date": "1994", "authors": "Lebrun JJ, Ali S, Sofer L, Ullrich A, Kelly PA", "reference": { "type": "PubMed", "id": "8188682", "url": "https://pubmed.ncbi.nlm.nih.gov/8188682" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P42229-1", "protein_name": "Signal transducer and activator of transcription 5A", "gene_name": "STAT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78536-1", "protein_name": "Disintegrin and metalloproteinase domain-containing protein 17", "gene_name": "ADAM17", "tax_name": "Human" }, { "uniprot_canonical_ac": "P28482-1", "protein_name": "Mitogen-activated protein kinase 1", "gene_name": "MAPK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15524-1", "protein_name": "Suppressor of cytokine signaling 1", "gene_name": "SOCS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51692-1", "protein_name": "Signal transducer and activator of transcription 5B", "gene_name": "STAT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60674-1", "protein_name": "Tyrosine-protein kinase JAK2", "gene_name": "JAK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NSE2-1", "protein_name": "Cytokine-inducible SH2-containing protein", "gene_name": "CISH", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01236-1", "protein_name": "Prolactin", "gene_name": "PRL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01242-1", "protein_name": "Growth hormone variant", "gene_name": "GH2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P18031-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 1", "gene_name": "PTPN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10912-1", "protein_name": "Growth hormone receptor", "gene_name": "GHR", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14508-1", "protein_name": "Suppressor of cytokine signaling 2", "gene_name": "SOCS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29350-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 6", "gene_name": "PTPN6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0DML2-1", "protein_name": "Chorionic somatomammotropin hormone 1", "gene_name": "CSH1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16471-1", "protein_name": "Prolactin receptor", "gene_name": "PRLR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y4H2-1", "protein_name": "Insulin receptor substrate 2", "gene_name": "IRS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07948-1", "protein_name": "Tyrosine-protein kinase Lyn", "gene_name": "LYN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01241-1", "protein_name": "Somatotropin", "gene_name": "CSH1; CSH2; GH1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14543-1", "protein_name": "Suppressor of cytokine signaling 3", "gene_name": "SOCS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40763-1", "protein_name": "Signal transducer and activator of transcription 3", "gene_name": "STAT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42224-1", "protein_name": "Signal transducer and activator of transcription 1-alpha/beta", "gene_name": "STAT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27361-1", "protein_name": "Mitogen-activated protein kinase 3", "gene_name": "MAPK3", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P42229", "url": "https://www.uniprot.org/uniprotkb/P42229" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.8188682", "abstract": "", "glycosylation": [], "mutagenesis": 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Burkhardt AL, Bolen JB, Geahlen RL, Tkatch LS, Tweardy DJ", "reference": { "type": "PubMed", "id": "8197119", "url": "https://pubmed.ncbi.nlm.nih.gov/8197119" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P42229-1", "protein_name": "Signal transducer and activator of transcription 5A", "gene_name": "STAT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08631-1", "protein_name": "Tyrosine-protein kinase HCK", "gene_name": "HCK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P43405-1", "protein_name": "Tyrosine-protein kinase SYK", "gene_name": "SYK", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15524-1", "protein_name": "Suppressor of cytokine signaling 1", "gene_name": "SOCS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99062-1", "protein_name": "Granulocyte colony-stimulating factor receptor", "gene_name": "CSF3R", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51692-1", "protein_name": "Signal transducer and activator of transcription 5B", "gene_name": "STAT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60674-1", "protein_name": "Tyrosine-protein kinase JAK2", "gene_name": "JAK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06124-2", "protein_name": "Tyrosine-protein phosphatase non-receptor type 11", "gene_name": "PTPN11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07948-1", "protein_name": "Tyrosine-protein kinase Lyn", "gene_name": "LYN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09919-1", "protein_name": "Granulocyte colony-stimulating factor", "gene_name": "CSF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29597-1", "protein_name": "Non-receptor tyrosine-protein kinase TYK2", "gene_name": "TYK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14543-1", "protein_name": "Suppressor of cytokine signaling 3", "gene_name": "SOCS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40763-1", "protein_name": "Signal transducer and activator of transcription 3", "gene_name": "STAT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01116-1", "protein_name": "GTPase KRas", "gene_name": "KRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42224-1", "protein_name": "Signal transducer and activator of transcription 1-alpha/beta", "gene_name": "STAT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23458-1", "protein_name": "Tyrosine-protein kinase JAK1", "gene_name": "JAK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29353-1", "protein_name": "SHC-transforming protein 1", "gene_name": "SHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62993-1", "protein_name": "Growth factor receptor-bound protein 2", "gene_name": "GRB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQC2-1", "protein_name": "GRB2-associated-binding protein 2", "gene_name": "GAB2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P42229", "url": "https://www.uniprot.org/uniprotkb/P42229" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.8197119", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 19 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Interleukin-2 receptor gamma chain: a functional component of the interleukin-7 receptor.", "journal": "Science (New York, N.Y.)", "date": "1993", "authors": "Noguchi M, Nakamura Y, Russell SM, Ziegler SF, Tsang M, Cao X, Leonard WJ", "reference": { "type": "PubMed", "id": "8266077", "url": "https://pubmed.ncbi.nlm.nih.gov/8266077" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P42229-1", "protein_name": "Signal transducer and activator of transcription 5A", "gene_name": "STAT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51532-1", "protein_name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4", "gene_name": "SMARCA4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15524-1", "protein_name": "Suppressor of cytokine signaling 1", "gene_name": "SOCS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51692-1", "protein_name": "Signal transducer and activator of transcription 5B", "gene_name": "STAT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P13232-1", "protein_name": "Interleukin-7", "gene_name": "IL7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16871-1", "protein_name": "Interleukin-7 receptor subunit alpha", "gene_name": "IL7R", "tax_name": "Human" }, { "uniprot_canonical_ac": "P31785-1", "protein_name": "Cytokine receptor common subunit gamma", "gene_name": "IL2RG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NSE2-1", "protein_name": "Cytokine-inducible SH2-containing protein", "gene_name": "CISH", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14508-1", "protein_name": "Suppressor of cytokine signaling 2", "gene_name": "SOCS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52333-1", "protein_name": "Tyrosine-protein kinase JAK3", "gene_name": "JAK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HC73-1", "protein_name": "Cytokine receptor-like factor 2", "gene_name": "CRLF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y4H2-1", "protein_name": "Insulin receptor substrate 2", "gene_name": "IRS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68431-1", "protein_name": "Histone H3.1", "gene_name": "H3C10; H3C11; H3C12; H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92569-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit gamma", "gene_name": "PIK3R3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q969D9-1", "protein_name": "Thymic stromal lymphopoietin", "gene_name": "TSLP", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14210-1", "protein_name": "Hepatocyte growth factor", "gene_name": "HGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40763-1", "protein_name": "Signal transducer and activator of transcription 3", "gene_name": "STAT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q71DI3-1", "protein_name": "Histone H3.2", "gene_name": "H3C13; H3C14; H3C15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NSI6-1", "protein_name": "Bromodomain and WD repeat-containing protein 1", "gene_name": "BRWD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15918-1", "protein_name": "V(D)J recombination-activating protein 1", "gene_name": "RAG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P55895-1", "protein_name": "V(D)J recombination-activating protein 2", "gene_name": "RAG2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23458-1", "protein_name": "Tyrosine-protein kinase JAK1", "gene_name": "JAK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P42229", "url": "https://www.uniprot.org/uniprotkb/P42229" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.8266077", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 25 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 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"The adapter protein Shc interacts with the interleukin-2 (IL-2) receptor upon IL-2 stimulation.", "journal": "The Journal of biological chemistry", "date": "1994", "authors": "Ravichandran KS, Burakoff SJ", "reference": { "type": "PubMed", "id": "8294403", "url": "https://pubmed.ncbi.nlm.nih.gov/8294403" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P42229-1", "protein_name": "Signal transducer and activator of transcription 5A", "gene_name": "STAT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P43405-1", "protein_name": "Tyrosine-protein kinase SYK", "gene_name": "SYK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92835-1", "protein_name": "Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1", "gene_name": "INPP5D", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51692-1", "protein_name": "Signal transducer and activator of transcription 5B", "gene_name": "STAT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14784-1", "protein_name": "Interleukin-2 receptor subunit beta", "gene_name": "IL2RB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01344-1", "protein_name": "Interleukin-5 receptor subunit alpha", "gene_name": "IL5RA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08700-1", "protein_name": "Interleukin-3", "gene_name": "IL3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P26951-1", "protein_name": "Interleukin-3 receptor subunit alpha", "gene_name": "IL3RA", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60674-1", "protein_name": "Tyrosine-protein kinase JAK2", "gene_name": "JAK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05113-1", "protein_name": "Interleukin-5", "gene_name": "IL5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P31785-1", "protein_name": "Cytokine receptor common subunit gamma", "gene_name": "IL2RG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60568-1", "protein_name": "Interleukin-2", "gene_name": "IL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01589-1", "protein_name": "Interleukin-2 receptor subunit alpha", "gene_name": "IL2RA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29350-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 6", "gene_name": "PTPN6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52333-1", "protein_name": "Tyrosine-protein kinase JAK3", "gene_name": "JAK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07889-1", "protein_name": "Son of sevenless homolog 1", "gene_name": "SOS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04141-1", "protein_name": "Granulocyte-macrophage colony-stimulating factor", "gene_name": "CSF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P32927-1", "protein_name": "Cytokine receptor common subunit beta", "gene_name": "CSF2RB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92569-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit gamma", "gene_name": "PIK3R3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15357-1", "protein_name": "Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2", "gene_name": "INPPL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06239-1", "protein_name": "Tyrosine-protein kinase Lck", "gene_name": "LCK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15509-1", "protein_name": "Granulocyte-macrophage colony-stimulating factor receptor subunit alpha", "gene_name": "CSF2RA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00329-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform", "gene_name": "PIK3CD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14289-1", "protein_name": "Protein-tyrosine kinase 2-beta", "gene_name": "PTK2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23458-1", "protein_name": "Tyrosine-protein kinase JAK1", "gene_name": "JAK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29353-1", "protein_name": "SHC-transforming protein 1", "gene_name": "SHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQC2-1", "protein_name": "GRB2-associated-binding protein 2", "gene_name": "GAB2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P42229", "url": "https://www.uniprot.org/uniprotkb/P42229" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.8294403", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 31 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Identification of JAK2 as a growth hormone receptor-associated tyrosine kinase.", "journal": "Cell", "date": "1993", "authors": "Argetsinger LS, Campbell GS, Yang X, Witthuhn BA, Silvennoinen O, Ihle JN, Carter-Su C", "reference": { "type": "PubMed", "id": "8343952", "url": "https://pubmed.ncbi.nlm.nih.gov/8343952" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P42229-1", "protein_name": "Signal transducer and activator of transcription 5A", "gene_name": "STAT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78536-1", "protein_name": "Disintegrin and metalloproteinase domain-containing protein 17", "gene_name": "ADAM17", "tax_name": "Human" }, { "uniprot_canonical_ac": "P28482-1", "protein_name": "Mitogen-activated protein kinase 1", "gene_name": "MAPK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15524-1", "protein_name": "Suppressor of cytokine signaling 1", "gene_name": "SOCS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51692-1", "protein_name": "Signal transducer and activator of transcription 5B", "gene_name": "STAT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60674-1", "protein_name": "Tyrosine-protein kinase JAK2", "gene_name": "JAK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NSE2-1", "protein_name": "Cytokine-inducible SH2-containing protein", "gene_name": "CISH", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01236-1", "protein_name": "Prolactin", "gene_name": "PRL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01242-1", "protein_name": "Growth hormone variant", "gene_name": "GH2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P18031-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 1", "gene_name": "PTPN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10912-1", "protein_name": "Growth hormone receptor", "gene_name": "GHR", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14508-1", "protein_name": "Suppressor of cytokine signaling 2", "gene_name": "SOCS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29350-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 6", "gene_name": "PTPN6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0DML2-1", "protein_name": "Chorionic somatomammotropin hormone 1", "gene_name": "CSH1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16471-1", "protein_name": "Prolactin receptor", "gene_name": "PRLR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y4H2-1", "protein_name": "Insulin receptor substrate 2", "gene_name": "IRS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07948-1", "protein_name": "Tyrosine-protein kinase Lyn", "gene_name": "LYN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01241-1", "protein_name": "Somatotropin", "gene_name": "CSH1; CSH2; GH1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14543-1", "protein_name": "Suppressor of cytokine signaling 3", "gene_name": "SOCS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40763-1", "protein_name": "Signal transducer and activator of transcription 3", "gene_name": "STAT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42224-1", "protein_name": "Signal transducer and activator of transcription 1-alpha/beta", "gene_name": "STAT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27361-1", "protein_name": "Mitogen-activated protein kinase 3", "gene_name": "MAPK3", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P42229", "url": "https://www.uniprot.org/uniprotkb/P42229" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.8343952", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 23 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "A novel dimer configuration revealed by the crystal structure at 2.4 A resolution of human interleukin-5.", "journal": "Nature", "date": "1993", "authors": "Milburn MV, Hassell AM, Lambert MH, Jordan SR, Proudfoot AE, Graber P, Wells TN", "reference": { "type": "PubMed", "id": "8483502", "url": "https://pubmed.ncbi.nlm.nih.gov/8483502" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P42229-1", "protein_name": "Signal transducer and activator of transcription 5A", "gene_name": "STAT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75462-1", "protein_name": "Cytokine receptor-like factor 1", "gene_name": "CRLF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51692-1", "protein_name": "Signal transducer and activator of transcription 5B", "gene_name": "STAT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01344-1", "protein_name": "Interleukin-5 receptor subunit alpha", "gene_name": "IL5RA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08700-1", "protein_name": "Interleukin-3", "gene_name": "IL3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P26951-1", "protein_name": "Interleukin-3 receptor subunit alpha", "gene_name": "IL3RA", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60674-1", "protein_name": "Tyrosine-protein kinase JAK2", "gene_name": "JAK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05113-1", "protein_name": "Interleukin-5", "gene_name": "IL5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40189-1", "protein_name": "Interleukin-6 receptor subunit beta", "gene_name": "IL6ST", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NEV9-1", "protein_name": "Interleukin-27 subunit alpha", "gene_name": "IL27", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14213-1", "protein_name": "Interleukin-27 subunit beta", "gene_name": "EBI3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29350-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 6", "gene_name": "PTPN6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04141-1", "protein_name": "Granulocyte-macrophage colony-stimulating factor", "gene_name": "CSF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P32927-1", "protein_name": 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"uniprot_canonical_ac": "P42680-1", "protein_name": "Tyrosine-protein kinase Tec", "gene_name": "TEC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29597-1", "protein_name": "Non-receptor tyrosine-protein kinase TYK2", "gene_name": "TYK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40763-1", "protein_name": "Signal transducer and activator of transcription 3", "gene_name": "STAT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UWB1-1", "protein_name": "Interleukin-27 receptor subunit alpha", "gene_name": "IL27RA", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00329-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform", "gene_name": "PIK3CD", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42224-1", "protein_name": "Signal transducer and activator of transcription 1-alpha/beta", "gene_name": "STAT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23458-1", "protein_name": "Tyrosine-protein kinase JAK1", "gene_name": "JAK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29353-1", "protein_name": "SHC-transforming protein 1", "gene_name": "SHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63104-1", "protein_name": "14-3-3 protein zeta/delta", "gene_name": "YWHAZ", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15498-1", "protein_name": "Proto-oncogene vav", "gene_name": "VAV1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P42229", "url": "https://www.uniprot.org/uniprotkb/P42229" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo 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"authors": "Anderson DM, Kumaki S, Ahdieh M, Bertles J, Tometsko M, Loomis A, Giri J, Copeland NG, Gilbert DJ, Jenkins NA, et al.", "reference": { "type": "PubMed", "id": "8530383", "url": "https://pubmed.ncbi.nlm.nih.gov/8530383" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P42229-1", "protein_name": "Signal transducer and activator of transcription 5A", "gene_name": "STAT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51692-1", "protein_name": "Signal transducer and activator of transcription 5B", "gene_name": "STAT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14784-1", "protein_name": "Interleukin-2 receptor subunit beta", "gene_name": "IL2RB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P31785-1", "protein_name": "Cytokine receptor common subunit gamma", "gene_name": "IL2RG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52333-1", "protein_name": "Tyrosine-protein kinase JAK3", "gene_name": "JAK3", "tax_name": "Human" 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"site_lbl": "Tyr694", "uniprot_canonical_ac": "P42229-1" }, { "start_pos": 694, "end_pos": 694, "kinase_uniprot_canonical_ac": "Q06187-1", "kinase_gene_name": "BTK", "residue": "Tyr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P42229", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42229" }, { "database": "PubMed", "id": "11413148", "url": "https://pubmed.ncbi.nlm.nih.gov/11413148" }, { "database": "PubMed", "id": "16497976", "url": "https://pubmed.ncbi.nlm.nih.gov/16497976" }, { "database": "PubMed", "id": "17016520", "url": "https://pubmed.ncbi.nlm.nih.gov/17016520" }, { "database": "PubMed", "id": "17389395", "url": "https://pubmed.ncbi.nlm.nih.gov/17389395" }, { "database": "PubMed", "id": "7925280", "url": "https://pubmed.ncbi.nlm.nih.gov/7925280" }, { "database": "PubMed", "id": "8617237", "url": "https://pubmed.ncbi.nlm.nih.gov/8617237" } ], "site_lbl": "Tyr694", "uniprot_canonical_ac": "P42229-1" } ], "record_id": "pubmed.8617237", "abstract": 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Reconstitution of interleukin-2-induced Stat5A and Stat5B DNA binding activity in COS-7 cells.", "journal": "The Journal of biological chemistry", "date": "1996", "authors": "Lin JX, Mietz J, Modi WS, John S, Leonard WJ", "reference": { "type": "PubMed", "id": "8631883", "url": "https://pubmed.ncbi.nlm.nih.gov/8631883" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P42229-1", "protein_name": "Signal transducer and activator of transcription 5A", "gene_name": "STAT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P43405-1", "protein_name": "Tyrosine-protein kinase SYK", "gene_name": "SYK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51692-1", "protein_name": "Signal transducer and activator of transcription 5B", "gene_name": "STAT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14784-1", "protein_name": "Interleukin-2 receptor subunit beta", "gene_name": "IL2RB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P31785-1", 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"uniprot_canonical_ac": "P29353-1", "protein_name": "SHC-transforming protein 1", "gene_name": "SHC1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P42229", "url": "https://www.uniprot.org/uniprotkb/P42229" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.8643566", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 12 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { 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0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Evidence for a physical association between the Shc-PTB domain and the beta c chain of the granulocyte-macrophage colony-stimulating factor receptor.", "journal": "The Journal of biological chemistry", "date": "1996", "authors": "Pratt JC, Weiss M, Sieff CA, Shoelson SE, Burakoff SJ, Ravichandran KS", "reference": { "type": "PubMed", "id": "8647804", "url": "https://pubmed.ncbi.nlm.nih.gov/8647804" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P42229-1", "protein_name": "Signal transducer and activator of transcription 5A", "gene_name": "STAT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51692-1", "protein_name": "Signal transducer and activator of transcription 5B", "gene_name": "STAT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01344-1", "protein_name": "Interleukin-5 receptor subunit alpha", "gene_name": "IL5RA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08700-1", "protein_name": "Interleukin-3", "gene_name": "IL3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P26951-1", "protein_name": "Interleukin-3 receptor subunit alpha", "gene_name": "IL3RA", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60674-1", "protein_name": "Tyrosine-protein kinase JAK2", "gene_name": "JAK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05113-1", "protein_name": "Interleukin-5", "gene_name": "IL5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29350-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 6", "gene_name": "PTPN6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04141-1", "protein_name": "Granulocyte-macrophage colony-stimulating factor", "gene_name": "CSF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P32927-1", "protein_name": "Cytokine receptor common subunit beta", "gene_name": "CSF2RB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P17612-1", "protein_name": "cAMP-dependent protein kinase catalytic subunit alpha", "gene_name": "PRKACA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92569-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit gamma", "gene_name": "PIK3R3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06124-2", "protein_name": "Tyrosine-protein phosphatase non-receptor type 11", "gene_name": "PTPN11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15509-1", "protein_name": "Granulocyte-macrophage colony-stimulating factor receptor subunit alpha", "gene_name": "CSF2RA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42680-1", "protein_name": "Tyrosine-protein kinase Tec", "gene_name": "TEC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00329-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform", "gene_name": "PIK3CD", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29353-1", "protein_name": "SHC-transforming protein 1", "gene_name": "SHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63104-1", "protein_name": "14-3-3 protein zeta/delta", "gene_name": "YWHAZ", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15498-1", "protein_name": "Proto-oncogene vav", "gene_name": "VAV1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P42229", "url": "https://www.uniprot.org/uniprotkb/P42229" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.8647804", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 23 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Different interleukin 2 receptor beta-chain tyrosines couple to at least two signaling pathways and synergistically mediate interleukin 2-induced proliferation.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "1996", "authors": "Friedmann MC, Migone TS, Russell SM, Leonard WJ", "reference": { "type": "PubMed", "id": "8700888", "url": "https://pubmed.ncbi.nlm.nih.gov/8700888" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P42229-1", "protein_name": "Signal transducer and activator of transcription 5A", "gene_name": "STAT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P43405-1", "protein_name": "Tyrosine-protein kinase SYK", "gene_name": "SYK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51692-1", "protein_name": "Signal transducer and activator of transcription 5B", "gene_name": "STAT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14784-1", "protein_name": "Interleukin-2 receptor subunit beta", "gene_name": "IL2RB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P31785-1", "protein_name": "Cytokine receptor common subunit gamma", "gene_name": "IL2RG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60568-1", "protein_name": "Interleukin-2", "gene_name": "IL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01589-1", "protein_name": "Interleukin-2 receptor subunit alpha", "gene_name": "IL2RA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52333-1", "protein_name": "Tyrosine-protein kinase JAK3", "gene_name": "JAK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06239-1", "protein_name": "Tyrosine-protein kinase Lck", "gene_name": "LCK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14289-1", "protein_name": "Protein-tyrosine kinase 2-beta", "gene_name": "PTK2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23458-1", "protein_name": "Tyrosine-protein kinase JAK1", "gene_name": "JAK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29353-1", "protein_name": "SHC-transforming protein 1", "gene_name": "SHC1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P42229", "url": "https://www.uniprot.org/uniprotkb/P42229" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 364, "end_pos": 364, "kinase_uniprot_canonical_ac": "P23458-1", "kinase_gene_name": "JAK1", "residue": "Tyr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P14784", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P14784" }, { "database": "PubMed", "id": "8700888", "url": "https://pubmed.ncbi.nlm.nih.gov/8700888" } ], "site_lbl": "Tyr364", "uniprot_canonical_ac": "P14784-1" } ], "record_id": "pubmed.8700888", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 12 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Distinct tyrosine residues within the interleukin-2 receptor beta chain drive signal transduction specificity, redundancy, and diversity.", "journal": "The Journal of biological chemistry", "date": "1996", "authors": "Gaffen SL, Lai SY, Ha M, Liu X, Hennighausen L, Greene WC, Goldsmith MA", "reference": { "type": "PubMed", "id": "8702919", "url": "https://pubmed.ncbi.nlm.nih.gov/8702919" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P42229-1", "protein_name": "Signal transducer and activator of transcription 5A", "gene_name": "STAT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51532-1", "protein_name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4", "gene_name": "SMARCA4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P43405-1", "protein_name": "Tyrosine-protein kinase SYK", "gene_name": "SYK", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15524-1", "protein_name": "Suppressor of cytokine signaling 1", "gene_name": "SOCS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51692-1", "protein_name": "Signal transducer and activator of transcription 5B", "gene_name": "STAT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14784-1", "protein_name": "Interleukin-2 receptor subunit beta", "gene_name": "IL2RB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P13232-1", "protein_name": "Interleukin-7", "gene_name": "IL7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16871-1", "protein_name": "Interleukin-7 receptor subunit alpha", "gene_name": "IL7R", "tax_name": "Human" }, { "uniprot_canonical_ac": "P31785-1", "protein_name": "Cytokine receptor common subunit gamma", "gene_name": "IL2RG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60568-1", "protein_name": "Interleukin-2", "gene_name": "IL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01589-1", "protein_name": "Interleukin-2 receptor subunit alpha", "gene_name": "IL2RA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NSE2-1", "protein_name": "Cytokine-inducible SH2-containing protein", "gene_name": "CISH", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14508-1", "protein_name": "Suppressor of cytokine signaling 2", "gene_name": "SOCS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52333-1", "protein_name": "Tyrosine-protein kinase JAK3", "gene_name": "JAK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HC73-1", "protein_name": "Cytokine receptor-like factor 2", "gene_name": "CRLF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y4H2-1", "protein_name": "Insulin receptor substrate 2", "gene_name": "IRS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68431-1", "protein_name": "Histone H3.1", "gene_name": "H3C10; H3C11; H3C12; H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92569-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit gamma", "gene_name": "PIK3R3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06239-1", "protein_name": "Tyrosine-protein kinase Lck", "gene_name": "LCK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q969D9-1", "protein_name": "Thymic stromal lymphopoietin", "gene_name": "TSLP", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14210-1", "protein_name": "Hepatocyte growth factor", "gene_name": "HGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40763-1", "protein_name": "Signal transducer and activator of transcription 3", "gene_name": "STAT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q71DI3-1", "protein_name": "Histone H3.2", "gene_name": "H3C13; H3C14; H3C15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NSI6-1", "protein_name": "Bromodomain and WD repeat-containing protein 1", "gene_name": "BRWD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15918-1", "protein_name": "V(D)J recombination-activating protein 1", "gene_name": "RAG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P55895-1", "protein_name": "V(D)J recombination-activating protein 2", "gene_name": "RAG2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14289-1", "protein_name": "Protein-tyrosine kinase 2-beta", "gene_name": "PTK2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23458-1", "protein_name": "Tyrosine-protein kinase JAK1", "gene_name": "JAK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29353-1", "protein_name": "SHC-transforming protein 1", "gene_name": "SHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P42229", "url": "https://www.uniprot.org/uniprotkb/P42229" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.8702919", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 32 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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precursor acute lymphoblastic leukemia cells and murine BAF3 cells involves activation of STAT1 and STAT5 mediated via the interleukin-7 receptor alpha chain.", "journal": "Leukemia", "date": "1996", "authors": "van der Plas DC, Smiers F, Pouwels K, Hoefsloot LH, Lowenberg B, Touw IP", "reference": { "type": "PubMed", "id": "8709637", "url": "https://pubmed.ncbi.nlm.nih.gov/8709637" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P42229-1", "protein_name": "Signal transducer and activator of transcription 5A", "gene_name": "STAT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51532-1", "protein_name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4", "gene_name": "SMARCA4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15524-1", "protein_name": "Suppressor of cytokine signaling 1", "gene_name": "SOCS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51692-1", "protein_name": "Signal 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"CRLF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y4H2-1", "protein_name": "Insulin receptor substrate 2", "gene_name": "IRS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68431-1", "protein_name": "Histone H3.1", "gene_name": "H3C10; H3C11; H3C12; H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92569-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit gamma", "gene_name": "PIK3R3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q969D9-1", "protein_name": "Thymic stromal lymphopoietin", "gene_name": "TSLP", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14210-1", "protein_name": "Hepatocyte growth factor", "gene_name": "HGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40763-1", "protein_name": "Signal transducer and activator of transcription 3", "gene_name": "STAT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q71DI3-1", "protein_name": "Histone H3.2", "gene_name": "H3C13; H3C14; H3C15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NSI6-1", "protein_name": "Bromodomain and WD repeat-containing protein 1", "gene_name": "BRWD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15918-1", "protein_name": "V(D)J recombination-activating protein 1", "gene_name": "RAG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P55895-1", "protein_name": "V(D)J recombination-activating protein 2", "gene_name": "RAG2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23458-1", "protein_name": "Tyrosine-protein kinase JAK1", "gene_name": "JAK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P42229", "url": "https://www.uniprot.org/uniprotkb/P42229" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.8709637", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 25 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", 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"count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "A single tyrosine of the interleukin-9 (IL-9) receptor is required for STAT activation, antiapoptotic activity, and growth regulation by IL-9.", "journal": "Molecular and cellular biology", "date": "1996", "authors": "Demoulin JB, Uyttenhove C, Van Roost E, DeLestre B, Donckers D, Van Snick J, Renauld JC", "reference": { "type": "PubMed", "id": "8756628", "url": "https://pubmed.ncbi.nlm.nih.gov/8756628" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P42229-1", "protein_name": "Signal transducer and activator of transcription 5A", "gene_name": "STAT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51692-1", "protein_name": "Signal transducer and activator of transcription 5B", "gene_name": "STAT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15248-1", "protein_name": "Interleukin-9", "gene_name": "IL9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P31785-1", "protein_name": "Cytokine receptor common subunit gamma", "gene_name": "IL2RG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01113-1", "protein_name": "Interleukin-9 receptor", "gene_name": "IL9R", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52333-1", "protein_name": "Tyrosine-protein kinase JAK3", "gene_name": "JAK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40763-1", "protein_name": "Signal transducer and activator of transcription 3", "gene_name": "STAT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42224-1", "protein_name": "Signal transducer and activator of transcription 1-alpha/beta", "gene_name": "STAT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23458-1", "protein_name": "Tyrosine-protein kinase JAK1", "gene_name": "JAK1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P42229", "url": "https://www.uniprot.org/uniprotkb/P42229" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 407, "end_pos": 407, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "Q01113", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q01113" }, { "database": "PubMed", "id": "8756628", "url": "https://pubmed.ncbi.nlm.nih.gov/8756628" } ], "site_lbl": "Tyr407", "uniprot_canonical_ac": "Q01113-1" } ], "record_id": "pubmed.8756628", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 9 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "IL-10 induces DNA binding activity of three STAT proteins (Stat1, Stat3, and Stat5) and their distinct combinatorial assembly in the promoters of selected genes.", "journal": "FEBS letters", "date": "1996", "authors": "Wehinger J, Gouilleux F, Groner B, Finke J, Mertelsmann R, Weber-Nordt RM", "reference": { "type": "PubMed", "id": "8830676", "url": "https://pubmed.ncbi.nlm.nih.gov/8830676" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P42229-1", "protein_name": "Signal 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"uniprot_canonical_ac": "P52630-3", "protein_name": "Signal transducer and activator of transcription 2", "gene_name": "STAT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NPH9-1", "protein_name": "Interleukin-26", "gene_name": "IL26", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14765-1", "protein_name": "Signal transducer and activator of transcription 4", "gene_name": "STAT4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06124-2", "protein_name": "Tyrosine-protein phosphatase non-receptor type 11", "gene_name": "PTPN11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29597-1", "protein_name": "Non-receptor tyrosine-protein kinase TYK2", "gene_name": "TYK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40763-1", "protein_name": "Signal transducer and activator of transcription 3", "gene_name": "STAT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9GZX6-1", "protein_name": "Interleukin-22", "gene_name": "IL22", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N6P7-1", "protein_name": "Interleukin-22 receptor subunit alpha-1", "gene_name": "IL22RA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q969J5-1", "protein_name": "Interleukin-22 receptor subunit alpha-2", "gene_name": "IL22RA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q08334-1", "protein_name": "Interleukin-10 receptor subunit beta", "gene_name": "IL10RB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IU57-1", "protein_name": "Interferon lambda receptor 1", "gene_name": "IFNLR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IU54-1", "protein_name": "Interferon lambda-1", "gene_name": "IFNL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IZJ0-1", "protein_name": "Interferon lambda-2", "gene_name": "IFNL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42224-1", "protein_name": "Signal transducer and activator of transcription 1-alpha/beta", "gene_name": "STAT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UXL0-1", "protein_name": "Interleukin-20 receptor subunit beta", "gene_name": "IL20RB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UHF4-1", "protein_name": "Interleukin-20 receptor subunit alpha", "gene_name": "IL20RA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23458-1", "protein_name": "Tyrosine-protein kinase JAK1", "gene_name": "JAK1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P42229", "url": "https://www.uniprot.org/uniprotkb/P42229" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.8830676", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 25 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": 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"glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "A novel pathway from phosphorylation of tyrosine residues 239/240 of Shc, contributing to suppress apoptosis by IL-3.", "journal": "The EMBO journal", "date": "1996", "authors": "Gotoh N, Tojo A, Shibuya M", "reference": { "type": "PubMed", "id": "8947042", "url": "https://pubmed.ncbi.nlm.nih.gov/8947042" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P42229-1", "protein_name": "Signal transducer and activator of transcription 5A", "gene_name": "STAT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51692-1", "protein_name": "Signal transducer and activator of transcription 5B", "gene_name": "STAT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01344-1", "protein_name": "Interleukin-5 receptor subunit alpha", "gene_name": "IL5RA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08700-1", "protein_name": "Interleukin-3", "gene_name": "IL3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P26951-1", "protein_name": "Interleukin-3 receptor subunit alpha", "gene_name": "IL3RA", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60674-1", "protein_name": "Tyrosine-protein kinase JAK2", "gene_name": "JAK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05113-1", "protein_name": "Interleukin-5", "gene_name": "IL5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29350-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 6", "gene_name": "PTPN6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04141-1", "protein_name": "Granulocyte-macrophage colony-stimulating factor", "gene_name": "CSF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P32927-1", "protein_name": "Cytokine receptor common subunit beta", "gene_name": "CSF2RB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P17612-1", "protein_name": "cAMP-dependent protein kinase catalytic subunit alpha", "gene_name": "PRKACA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92569-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit gamma", "gene_name": "PIK3R3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06124-2", "protein_name": "Tyrosine-protein phosphatase non-receptor type 11", "gene_name": "PTPN11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15509-1", "protein_name": "Granulocyte-macrophage colony-stimulating factor receptor subunit alpha", "gene_name": "CSF2RA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42680-1", "protein_name": "Tyrosine-protein kinase Tec", "gene_name": "TEC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00329-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform", "gene_name": "PIK3CD", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29353-1", "protein_name": "SHC-transforming protein 1", "gene_name": "SHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63104-1", "protein_name": "14-3-3 protein zeta/delta", "gene_name": "YWHAZ", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15498-1", "protein_name": "Proto-oncogene vav", "gene_name": "VAV1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P42229", "url": "https://www.uniprot.org/uniprotkb/P42229" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.8947042", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 23 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"authors": "Tian SS, Tapley P, Sincich C, Stein RB, Rosen J, Lamb P", "reference": { "type": "PubMed", "id": "8977235", "url": "https://pubmed.ncbi.nlm.nih.gov/8977235" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P42229-1", "protein_name": "Signal transducer and activator of transcription 5A", "gene_name": "STAT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08631-1", "protein_name": "Tyrosine-protein kinase HCK", "gene_name": "HCK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P43405-1", "protein_name": "Tyrosine-protein kinase SYK", "gene_name": "SYK", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15524-1", "protein_name": "Suppressor of cytokine signaling 1", "gene_name": "SOCS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99062-1", "protein_name": "Granulocyte colony-stimulating factor receptor", "gene_name": "CSF3R", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51692-1", "protein_name": "Signal transducer and activator of transcription 5B", "gene_name": "STAT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60674-1", "protein_name": "Tyrosine-protein kinase JAK2", "gene_name": "JAK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06124-2", "protein_name": "Tyrosine-protein phosphatase non-receptor type 11", "gene_name": "PTPN11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07948-1", "protein_name": "Tyrosine-protein kinase Lyn", "gene_name": "LYN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09919-1", "protein_name": "Granulocyte colony-stimulating factor", "gene_name": "CSF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29597-1", "protein_name": "Non-receptor tyrosine-protein kinase TYK2", "gene_name": "TYK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14543-1", "protein_name": "Suppressor of cytokine signaling 3", "gene_name": "SOCS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40763-1", "protein_name": "Signal transducer and activator of transcription 3", "gene_name": "STAT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01116-1", "protein_name": "GTPase KRas", "gene_name": "KRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42224-1", "protein_name": "Signal transducer and activator of transcription 1-alpha/beta", "gene_name": "STAT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23458-1", "protein_name": "Tyrosine-protein kinase JAK1", "gene_name": "JAK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29353-1", "protein_name": "SHC-transforming protein 1", "gene_name": "SHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62993-1", "protein_name": "Growth factor receptor-bound protein 2", "gene_name": "GRB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQC2-1", "protein_name": "GRB2-associated-binding protein 2", "gene_name": "GAB2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P42229", "url": "https://www.uniprot.org/uniprotkb/P42229" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.8977235", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 19 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], 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Cytoplasmic domain mutational analysis and evidence for receptor homo-oligomerization.", "journal": "The Journal of biological chemistry", "date": "1997", "authors": "White DW, Kuropatwinski KK, Devos R, Baumann H, Tartaglia LA", "reference": { "type": "PubMed", "id": "9020115", "url": "https://pubmed.ncbi.nlm.nih.gov/9020115" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P42229-1", "protein_name": "Signal transducer and activator of transcription 5A", "gene_name": "STAT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51692-1", "protein_name": "Signal transducer and activator of transcription 5B", "gene_name": "STAT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60674-1", "protein_name": "Tyrosine-protein kinase JAK2", "gene_name": "JAK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41159-1", "protein_name": "Leptin", "gene_name": "LEP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y4H2-1", "protein_name": "Insulin 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"count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "A single STAT recruitment module in a chimeric cytokine receptor complex is sufficient for STAT activation.", "journal": "The Journal of biological chemistry", "date": "1997", "authors": "Behrmann I, Janzen C, Gerhartz C, Schmitz-Van de Leur H, Hermanns H, Heesel B, Graeve L, Horn F, Tavernier J, Heinrich PC", "reference": { "type": "PubMed", "id": "9030599", "url": "https://pubmed.ncbi.nlm.nih.gov/9030599" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P42229-1", "protein_name": "Signal transducer and activator of transcription 5A", "gene_name": "STAT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78536-1", "protein_name": "Disintegrin and metalloproteinase domain-containing protein 17", "gene_name": "ADAM17", "tax_name": "Human" }, { "uniprot_canonical_ac": "P28482-1", "protein_name": "Mitogen-activated protein kinase 1", "gene_name": "MAPK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P43405-1", "protein_name": "Tyrosine-protein kinase SYK", "gene_name": "SYK", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15524-1", "protein_name": "Suppressor of cytokine signaling 1", "gene_name": "SOCS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51692-1", "protein_name": "Signal transducer and activator of transcription 5B", "gene_name": "STAT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14784-1", "protein_name": "Interleukin-2 receptor subunit beta", "gene_name": "IL2RB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01344-1", "protein_name": "Interleukin-5 receptor subunit alpha", "gene_name": "IL5RA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08700-1", "protein_name": "Interleukin-3", "gene_name": "IL3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P26951-1", "protein_name": "Interleukin-3 receptor subunit alpha", "gene_name": "IL3RA", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60674-1", "protein_name": "Tyrosine-protein kinase JAK2", "gene_name": "JAK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05113-1", "protein_name": "Interleukin-5", "gene_name": "IL5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P31785-1", "protein_name": "Cytokine receptor common subunit gamma", "gene_name": "IL2RG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60568-1", "protein_name": "Interleukin-2", "gene_name": "IL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01589-1", "protein_name": "Interleukin-2 receptor subunit alpha", "gene_name": "IL2RA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NSE2-1", "protein_name": "Cytokine-inducible SH2-containing protein", "gene_name": "CISH", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01236-1", "protein_name": "Prolactin", "gene_name": "PRL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01242-1", "protein_name": "Growth hormone variant", "gene_name": "GH2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P18031-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 1", "gene_name": "PTPN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10912-1", "protein_name": "Growth hormone receptor", "gene_name": "GHR", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14508-1", "protein_name": "Suppressor of cytokine signaling 2", "gene_name": "SOCS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29350-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 6", "gene_name": "PTPN6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52333-1", "protein_name": "Tyrosine-protein kinase JAK3", "gene_name": "JAK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04141-1", "protein_name": "Granulocyte-macrophage colony-stimulating factor", "gene_name": "CSF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0DML2-1", "protein_name": "Chorionic somatomammotropin hormone 1", "gene_name": "CSH1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P32927-1", "protein_name": "Cytokine receptor common subunit beta", "gene_name": "CSF2RB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16471-1", "protein_name": "Prolactin receptor", "gene_name": "PRLR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y4H2-1", "protein_name": "Insulin receptor substrate 2", "gene_name": "IRS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P17612-1", "protein_name": "cAMP-dependent protein kinase catalytic subunit alpha", "gene_name": "PRKACA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92569-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit gamma", "gene_name": "PIK3R3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06239-1", "protein_name": "Tyrosine-protein kinase Lck", "gene_name": "LCK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06124-2", "protein_name": "Tyrosine-protein phosphatase non-receptor type 11", "gene_name": "PTPN11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07948-1", "protein_name": "Tyrosine-protein kinase Lyn", "gene_name": "LYN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01241-1", "protein_name": "Somatotropin", "gene_name": "CSH1; CSH2; GH1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15509-1", "protein_name": "Granulocyte-macrophage colony-stimulating factor receptor subunit alpha", "gene_name": "CSF2RA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42680-1", "protein_name": "Tyrosine-protein kinase Tec", "gene_name": "TEC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14543-1", "protein_name": "Suppressor of cytokine signaling 3", "gene_name": "SOCS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40763-1", "protein_name": "Signal transducer and activator of transcription 3", "gene_name": "STAT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase 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"protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63104-1", "protein_name": "14-3-3 protein zeta/delta", "gene_name": "YWHAZ", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15498-1", "protein_name": "Proto-oncogene vav", "gene_name": "VAV1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P42229", "url": "https://www.uniprot.org/uniprotkb/P42229" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.9030599", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 51 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": 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"Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.9057652", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 7 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 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protein.", "journal": "Molecular endocrinology (Baltimore, Md.)", "date": "1997", "authors": "Ross RJ, Esposito N, Shen XY, Von Laue S, Chew SL, Dobson PR, Postel-Vinay MC, Finidori J", "reference": { "type": "PubMed", "id": "9058373", "url": "https://pubmed.ncbi.nlm.nih.gov/9058373" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P42229-1", "protein_name": "Signal transducer and activator of transcription 5A", "gene_name": "STAT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78536-1", "protein_name": "Disintegrin and metalloproteinase domain-containing protein 17", "gene_name": "ADAM17", "tax_name": "Human" }, { "uniprot_canonical_ac": "P28482-1", "protein_name": "Mitogen-activated protein kinase 1", "gene_name": "MAPK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15524-1", "protein_name": "Suppressor of cytokine signaling 1", "gene_name": "SOCS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51692-1", "protein_name": "Signal 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"table_stats": [ { "field": "total", "count": 23 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { 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"P23458-1", "protein_name": "Tyrosine-protein kinase JAK1", "gene_name": "JAK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29353-1", "protein_name": "SHC-transforming protein 1", "gene_name": "SHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62993-1", "protein_name": "Growth factor receptor-bound protein 2", "gene_name": "GRB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQC2-1", "protein_name": "GRB2-associated-binding protein 2", "gene_name": "GAB2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P42229", "url": "https://www.uniprot.org/uniprotkb/P42229" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.9126349", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 14 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "SHP1 and SHP2 protein-tyrosine phosphatases associate with betac after interleukin-3-induced receptor tyrosine phosphorylation. Identification of potential binding sites and substrates.", "journal": "The Journal of biological chemistry", "date": "1997", "authors": "Bone H, Dechert U, Jirik F, Schrader JW, Welham MJ", "reference": { "type": "PubMed", "id": "9162089", "url": "https://pubmed.ncbi.nlm.nih.gov/9162089" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P42229-1", "protein_name": "Signal transducer and activator of transcription 5A", "gene_name": "STAT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51692-1", "protein_name": "Signal transducer and activator of transcription 5B", "gene_name": "STAT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01344-1", "protein_name": "Interleukin-5 receptor subunit alpha", "gene_name": "IL5RA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08700-1", "protein_name": "Interleukin-3", "gene_name": "IL3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P26951-1", "protein_name": "Interleukin-3 receptor subunit alpha", "gene_name": "IL3RA", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60674-1", "protein_name": "Tyrosine-protein kinase JAK2", "gene_name": "JAK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05113-1", "protein_name": "Interleukin-5", "gene_name": "IL5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29350-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 6", "gene_name": "PTPN6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04141-1", "protein_name": "Granulocyte-macrophage colony-stimulating factor", "gene_name": "CSF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P32927-1", "protein_name": "Cytokine receptor common subunit beta", "gene_name": "CSF2RB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P17612-1", "protein_name": "cAMP-dependent protein kinase catalytic subunit alpha", "gene_name": "PRKACA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92569-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit gamma", "gene_name": "PIK3R3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06124-2", "protein_name": "Tyrosine-protein phosphatase non-receptor type 11", "gene_name": "PTPN11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15509-1", "protein_name": "Granulocyte-macrophage colony-stimulating factor receptor subunit alpha", "gene_name": "CSF2RA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42680-1", "protein_name": "Tyrosine-protein kinase Tec", "gene_name": "TEC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00329-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform", "gene_name": "PIK3CD", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29353-1", "protein_name": "SHC-transforming protein 1", "gene_name": "SHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63104-1", "protein_name": "14-3-3 protein zeta/delta", "gene_name": "YWHAZ", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15498-1", "protein_name": "Proto-oncogene vav", "gene_name": "VAV1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P42229", "url": "https://www.uniprot.org/uniprotkb/P42229" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 628, "end_pos": 628, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P32927", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32927" }, { "database": "PubMed", "id": "9677359", "url": "https://pubmed.ncbi.nlm.nih.gov/9677359" }, { "database": "IntAct", "id": "P32927", "url": "https://www.ebi.ac.uk/intact/interactors/id:P32927*" }, { "database": "PubMed", "id": "10704825", "url": "https://pubmed.ncbi.nlm.nih.gov/10704825" }, { "database": "PubMed", "id": "7528537", "url": "https://pubmed.ncbi.nlm.nih.gov/7528537" }, { "database": "PubMed", "id": "9162089", "url": "https://pubmed.ncbi.nlm.nih.gov/9162089" }, { "database": "PubMed", "id": "9973406", "url": "https://pubmed.ncbi.nlm.nih.gov/9973406" }, { "database": "PRO", "id": "P32927", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=P32927" } ], "site_lbl": "Tyr628", "uniprot_canonical_ac": "P32927-1" } ], "record_id": "pubmed.9162089", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 23 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Jak1 plays an essential role for receptor phosphorylation and Stat activation in response to granulocyte colony-stimulating factor.", "journal": "Blood", "date": "1997", "authors": "Shimoda K, Feng J, Murakami H, Nagata S, Watling D, Rogers NC, Stark GR, Kerr IM, Ihle JN", "reference": { "type": "PubMed", "id": "9226159", "url": "https://pubmed.ncbi.nlm.nih.gov/9226159" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P42229-1", "protein_name": "Signal transducer and activator of transcription 5A", "gene_name": "STAT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08631-1", "protein_name": "Tyrosine-protein kinase HCK", "gene_name": "HCK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P43405-1", "protein_name": "Tyrosine-protein kinase SYK", "gene_name": "SYK", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15524-1", "protein_name": "Suppressor of cytokine signaling 1", "gene_name": "SOCS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99062-1", "protein_name": "Granulocyte colony-stimulating factor receptor", "gene_name": "CSF3R", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51692-1", "protein_name": "Signal transducer and activator of transcription 5B", "gene_name": "STAT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60674-1", "protein_name": "Tyrosine-protein kinase JAK2", "gene_name": "JAK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06124-2", "protein_name": "Tyrosine-protein phosphatase non-receptor type 11", "gene_name": "PTPN11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07948-1", "protein_name": "Tyrosine-protein kinase Lyn", "gene_name": "LYN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09919-1", "protein_name": "Granulocyte colony-stimulating factor", "gene_name": "CSF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29597-1", "protein_name": "Non-receptor tyrosine-protein kinase TYK2", "gene_name": "TYK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14543-1", "protein_name": "Suppressor of cytokine signaling 3", "gene_name": "SOCS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40763-1", "protein_name": "Signal transducer and activator of transcription 3", "gene_name": "STAT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01116-1", "protein_name": "GTPase KRas", "gene_name": "KRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42224-1", "protein_name": "Signal transducer and activator of transcription 1-alpha/beta", "gene_name": "STAT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23458-1", "protein_name": "Tyrosine-protein kinase JAK1", "gene_name": "JAK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29353-1", "protein_name": "SHC-transforming protein 1", "gene_name": "SHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62993-1", "protein_name": "Growth factor receptor-bound protein 2", "gene_name": "GRB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQC2-1", "protein_name": "GRB2-associated-binding protein 2", "gene_name": "GAB2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P42229", "url": "https://www.uniprot.org/uniprotkb/P42229" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.9226159", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 19 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Differential association of phosphatidylinositol 3-kinase with insulin receptor substrate (IRS)-1 and IRS-2 in human thymocytes in response to IL-7.", "journal": "Journal of immunology (Baltimore, Md. : 1950)", "date": "1997", "authors": "Sharfe N, Roifman CM", "reference": { "type": "PubMed", "id": "9233603", "url": "https://pubmed.ncbi.nlm.nih.gov/9233603" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P42229-1", "protein_name": "Signal transducer and activator of transcription 5A", "gene_name": "STAT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51532-1", "protein_name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4", "gene_name": "SMARCA4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15524-1", "protein_name": "Suppressor of cytokine signaling 1", "gene_name": "SOCS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51692-1", "protein_name": "Signal transducer and activator of transcription 5B", "gene_name": "STAT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P13232-1", "protein_name": "Interleukin-7", "gene_name": "IL7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16871-1", "protein_name": "Interleukin-7 receptor subunit alpha", "gene_name": "IL7R", "tax_name": "Human" }, { "uniprot_canonical_ac": "P31785-1", "protein_name": "Cytokine receptor common subunit gamma", "gene_name": "IL2RG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NSE2-1", "protein_name": "Cytokine-inducible SH2-containing protein", "gene_name": "CISH", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14508-1", "protein_name": "Suppressor of cytokine signaling 2", "gene_name": "SOCS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52333-1", "protein_name": "Tyrosine-protein kinase JAK3", "gene_name": "JAK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HC73-1", 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"n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "IL-2 and IL-7 induce heterodimerization of STAT5 isoforms in human peripheral blood T lymphoblasts.", "journal": "Cellular immunology", "date": "1997", "authors": "Rosenthal LA, Winestock KD, Finbloom DS", "reference": { "type": "PubMed", "id": "9398404", "url": "https://pubmed.ncbi.nlm.nih.gov/9398404" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P42229-1", "protein_name": "Signal transducer and activator of transcription 5A", "gene_name": "STAT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51532-1", "protein_name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4", "gene_name": "SMARCA4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15524-1", "protein_name": "Suppressor of cytokine signaling 1", "gene_name": "SOCS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51692-1", "protein_name": "Signal transducer and activator of transcription 5B", "gene_name": "STAT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P13232-1", "protein_name": "Interleukin-7", "gene_name": "IL7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16871-1", "protein_name": "Interleukin-7 receptor subunit alpha", "gene_name": "IL7R", "tax_name": "Human" }, { "uniprot_canonical_ac": "P31785-1", "protein_name": "Cytokine receptor common subunit gamma", "gene_name": "IL2RG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NSE2-1", "protein_name": "Cytokine-inducible SH2-containing protein", "gene_name": "CISH", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14508-1", "protein_name": "Suppressor of cytokine signaling 2", "gene_name": "SOCS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52333-1", "protein_name": "Tyrosine-protein kinase JAK3", "gene_name": "JAK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HC73-1", "protein_name": "Cytokine receptor-like factor 2", "gene_name": "CRLF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y4H2-1", "protein_name": "Insulin receptor substrate 2", "gene_name": "IRS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68431-1", "protein_name": "Histone H3.1", "gene_name": "H3C10; H3C11; H3C12; H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92569-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit gamma", "gene_name": "PIK3R3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q969D9-1", "protein_name": "Thymic stromal lymphopoietin", "gene_name": "TSLP", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14210-1", "protein_name": "Hepatocyte growth factor", "gene_name": "HGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40763-1", "protein_name": "Signal transducer and activator of transcription 3", "gene_name": "STAT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q71DI3-1", "protein_name": "Histone H3.2", "gene_name": "H3C13; H3C14; H3C15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NSI6-1", "protein_name": "Bromodomain and WD repeat-containing protein 1", "gene_name": "BRWD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15918-1", "protein_name": "V(D)J recombination-activating protein 1", "gene_name": "RAG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P55895-1", "protein_name": "V(D)J recombination-activating protein 2", "gene_name": "RAG2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23458-1", "protein_name": "Tyrosine-protein kinase JAK1", "gene_name": "JAK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P42229", "url": "https://www.uniprot.org/uniprotkb/P42229" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.9398404", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 25 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Divergent signaling capacities of the long and short isoforms of the leptin receptor.", "journal": "The Journal of biological chemistry", "date": "1997", "authors": "Bjorbaek C, Uotani S, da Silva B, Flier JS", "reference": { "type": "PubMed", "id": "9405487", "url": "https://pubmed.ncbi.nlm.nih.gov/9405487" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P42229-1", "protein_name": "Signal transducer and activator of transcription 5A", "gene_name": "STAT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51692-1", "protein_name": "Signal transducer and activator of transcription 5B", "gene_name": "STAT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60674-1", "protein_name": "Tyrosine-protein kinase JAK2", "gene_name": "JAK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41159-1", "protein_name": "Leptin", "gene_name": "LEP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y4H2-1", "protein_name": "Insulin receptor substrate 2", "gene_name": "IRS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06124-2", "protein_name": "Tyrosine-protein phosphatase non-receptor type 11", "gene_name": "PTPN11", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14543-1", "protein_name": "Suppressor of cytokine signaling 3", "gene_name": "SOCS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40763-1", "protein_name": "Signal transducer and activator of transcription 3", "gene_name": "STAT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P42229", "url": "https://www.uniprot.org/uniprotkb/P42229" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.9405487", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 9 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": 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"glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Identification of a Cys motif in the common beta chain of the interleukin 3, granulocyte-macrophage colony-stimulating factor, and interleukin 5 receptors essential for disulfide-linked receptor heterodimerization and activation of all three receptors.", "journal": "The Journal of biological chemistry", "date": "1998", "authors": "Stomski FC, Woodcock JM, Zacharakis B, Bagley CJ, Sun Q, Lopez AF", "reference": { "type": "PubMed", "id": "9422786", "url": "https://pubmed.ncbi.nlm.nih.gov/9422786" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P42229-1", "protein_name": "Signal transducer and activator of transcription 5A", "gene_name": "STAT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51692-1", "protein_name": "Signal transducer and activator of transcription 5B", "gene_name": "STAT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01344-1", "protein_name": "Interleukin-5 receptor subunit alpha", "gene_name": "IL5RA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08700-1", "protein_name": "Interleukin-3", "gene_name": "IL3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P26951-1", "protein_name": "Interleukin-3 receptor subunit alpha", "gene_name": "IL3RA", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60674-1", "protein_name": "Tyrosine-protein kinase JAK2", "gene_name": "JAK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05113-1", "protein_name": "Interleukin-5", "gene_name": "IL5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29350-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 6", "gene_name": "PTPN6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04141-1", "protein_name": "Granulocyte-macrophage colony-stimulating factor", "gene_name": "CSF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P32927-1", "protein_name": "Cytokine receptor common subunit beta", "gene_name": "CSF2RB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P17612-1", "protein_name": "cAMP-dependent protein kinase catalytic subunit alpha", "gene_name": "PRKACA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92569-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit gamma", "gene_name": "PIK3R3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06124-2", "protein_name": "Tyrosine-protein phosphatase non-receptor type 11", "gene_name": "PTPN11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15509-1", "protein_name": "Granulocyte-macrophage colony-stimulating factor receptor subunit alpha", "gene_name": "CSF2RA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42680-1", "protein_name": "Tyrosine-protein kinase Tec", "gene_name": "TEC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00329-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform", "gene_name": "PIK3CD", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29353-1", "protein_name": "SHC-transforming protein 1", "gene_name": "SHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63104-1", "protein_name": "14-3-3 protein zeta/delta", "gene_name": "YWHAZ", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15498-1", "protein_name": "Proto-oncogene vav", "gene_name": "VAV1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P42229", "url": "https://www.uniprot.org/uniprotkb/P42229" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.9422786", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 23 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "FGFR1 is fused with a novel zinc-finger gene, ZNF198, in the t(8;13) leukaemia/lymphoma syndrome.", "journal": "Nature genetics", "date": "1998", "authors": "Xiao S, Nalabolu SR, Aster JC, Ma J, Abruzzo L, Jaffe ES, Stone R, Weissman SM, Hudson TJ, Fletcher JA", "reference": { "type": "PubMed", "id": "9425908", "url": "https://pubmed.ncbi.nlm.nih.gov/9425908" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P42229-1", "protein_name": "Signal transducer and activator of 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"protein_name": "Homeobox protein cut-like 1", "gene_name": "CUX1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40763-1", "protein_name": "Signal transducer and activator of transcription 3", "gene_name": "STAT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBW7-1", "protein_name": "Zinc finger MYM-type protein 2", "gene_name": "ZMYM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NVK5-1", "protein_name": "FGFR1 oncogene partner 2", "gene_name": "FGFR1OP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42224-1", "protein_name": "Signal transducer and activator of transcription 1-alpha/beta", "gene_name": "STAT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15164-1", "protein_name": "Transcription intermediary factor 1-alpha", "gene_name": "TRIM24", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q32MZ4-1", "protein_name": "Leucine-rich repeat flightless-interacting protein 1", "gene_name": "LRRFIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": 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"protein_name": "GTPase HRas", "gene_name": "HRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51692-1", "protein_name": "Signal transducer and activator of transcription 5B", "gene_name": "STAT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60674-1", "protein_name": "Tyrosine-protein kinase JAK2", "gene_name": "JAK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01111-1", "protein_name": "GTPase NRas", "gene_name": "NRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07889-1", "protein_name": "Son of sevenless homolog 1", "gene_name": "SOS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92569-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit gamma", "gene_name": "PIK3R3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": 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"protein_name": "Tyrosine-protein kinase Fyn", "gene_name": "FYN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10721-1", "protein_name": "Mast/stem cell growth factor receptor Kit", "gene_name": "KIT", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P42229", "url": "https://www.uniprot.org/uniprotkb/P42229" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.9438854", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 17 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": 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"uniprot_canonical_ac": "P51692-1", "protein_name": "Signal transducer and activator of transcription 5B", "gene_name": "STAT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14784-1", "protein_name": "Interleukin-2 receptor subunit beta", "gene_name": "IL2RB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P31785-1", "protein_name": "Cytokine receptor common subunit gamma", "gene_name": "IL2RG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60568-1", "protein_name": "Interleukin-2", "gene_name": "IL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01589-1", "protein_name": "Interleukin-2 receptor subunit alpha", "gene_name": "IL2RA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52333-1", "protein_name": "Tyrosine-protein kinase JAK3", "gene_name": "JAK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06239-1", "protein_name": "Tyrosine-protein kinase Lck", "gene_name": "LCK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14289-1", "protein_name": 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"uniprot_canonical_ac": "P23458-1", "protein_name": "Tyrosine-protein kinase JAK1", "gene_name": "JAK1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P42229", "url": "https://www.uniprot.org/uniprotkb/P42229" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.9535918", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 9 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, 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"n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Delineation of the regions of interleukin-2 (IL-2) receptor beta chain important for association of Jak1 and Jak3. Jak1-independent functional recruitment of Jak3 to Il-2Rbeta.", "journal": "The Journal of biological chemistry", "date": "1998", "authors": "Zhu MH, Berry JA, Russell SM, Leonard WJ", "reference": { "type": "PubMed", "id": "9553136", "url": "https://pubmed.ncbi.nlm.nih.gov/9553136" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P42229-1", "protein_name": "Signal transducer and activator of transcription 5A", "gene_name": "STAT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51532-1", "protein_name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4", "gene_name": "SMARCA4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15524-1", "protein_name": "Suppressor of cytokine signaling 1", "gene_name": "SOCS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51692-1", "protein_name": "Signal transducer and activator of transcription 5B", "gene_name": "STAT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P13232-1", "protein_name": "Interleukin-7", "gene_name": "IL7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16871-1", "protein_name": "Interleukin-7 receptor subunit alpha", "gene_name": "IL7R", "tax_name": "Human" }, { "uniprot_canonical_ac": "P31785-1", "protein_name": "Cytokine receptor common subunit gamma", "gene_name": "IL2RG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NSE2-1", "protein_name": "Cytokine-inducible SH2-containing protein", "gene_name": "CISH", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14508-1", "protein_name": "Suppressor of cytokine signaling 2", "gene_name": "SOCS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52333-1", "protein_name": "Tyrosine-protein kinase JAK3", "gene_name": "JAK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HC73-1", "protein_name": "Cytokine receptor-like factor 2", "gene_name": "CRLF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y4H2-1", "protein_name": "Insulin receptor substrate 2", "gene_name": "IRS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68431-1", "protein_name": "Histone H3.1", "gene_name": "H3C10; H3C11; H3C12; H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92569-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit gamma", "gene_name": "PIK3R3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q969D9-1", "protein_name": "Thymic stromal lymphopoietin", "gene_name": "TSLP", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14210-1", "protein_name": "Hepatocyte growth factor", "gene_name": "HGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40763-1", "protein_name": "Signal transducer and activator of transcription 3", "gene_name": "STAT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q71DI3-1", "protein_name": "Histone H3.2", "gene_name": "H3C13; H3C14; H3C15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NSI6-1", "protein_name": "Bromodomain and WD repeat-containing protein 1", "gene_name": "BRWD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15918-1", "protein_name": "V(D)J recombination-activating protein 1", "gene_name": "RAG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P55895-1", "protein_name": "V(D)J recombination-activating protein 2", "gene_name": "RAG2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23458-1", "protein_name": "Tyrosine-protein kinase JAK1", "gene_name": "JAK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P42229", "url": "https://www.uniprot.org/uniprotkb/P42229" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.9553136", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 25 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 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"Lyn physically associates with the erythropoietin receptor and may play a role in activation of the Stat5 pathway.", "journal": "Blood", "date": "1998", "authors": "Chin H, Arai A, Wakao H, Kamiyama R, Miyasaka N, Miura O", "reference": { "type": "PubMed", "id": "9573010", "url": "https://pubmed.ncbi.nlm.nih.gov/9573010" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P42229-1", "protein_name": "Signal transducer and activator of transcription 5A", "gene_name": "STAT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60674-1", "protein_name": "Tyrosine-protein kinase JAK2", "gene_name": "JAK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19235-1", "protein_name": "Erythropoietin receptor", "gene_name": "EPOR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25911-1", "protein_name": "Tyrosine-protein kinase Lyn", "gene_name": "Lyn", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q62120-1", "protein_name": "Tyrosine-protein kinase JAK2", "gene_name": "Jak2", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "P14753-1", "protein_name": "Erythropoietin receptor", "gene_name": "Epor", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y4H2-1", "protein_name": "Insulin receptor substrate 2", "gene_name": "IRS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07948-1", "protein_name": "Tyrosine-protein kinase Lyn", "gene_name": "LYN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01588-1", "protein_name": "Erythropoietin", "gene_name": "EPO", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P42229", "url": "https://www.uniprot.org/uniprotkb/P42229" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 694, "end_pos": 694, "kinase_uniprot_canonical_ac": "P07948-1", "kinase_gene_name": "LYN", "residue": "Tyr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P42229", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42229" }, { "database": "PubMed", "id": "9573010", "url": "https://pubmed.ncbi.nlm.nih.gov/9573010" } ], "site_lbl": "Tyr694", "uniprot_canonical_ac": "P42229-1" }, { "start_pos": 488, "end_pos": 488, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by JAK2", "evidence": [ { "database": "UniProtKB", "id": "P14753", "url": "https://www.uniprot.org/uniprotkb/P14753" }, { "database": "IntAct", "id": "P14753", "url": "https://www.ebi.ac.uk/intact/interactors/id:P14753*" }, { "database": "iPTMnet", "id": "P14753", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P14753" }, { "database": "PubMed", "id": "9573010", "url": "https://pubmed.ncbi.nlm.nih.gov/9573010" }, { "database": "PubMed", "id": "8639815", "url": "https://pubmed.ncbi.nlm.nih.gov/8639815" } ], "site_lbl": "Tyr488", "uniprot_canonical_ac": "P14753-1" }, { "start_pos": 503, "end_pos": 503, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by JAK2", "evidence": [ { "database": "UniProtKB", "id": "P14753", "url": "https://www.uniprot.org/uniprotkb/P14753" }, { "database": "IntAct", "id": "P14753", "url": "https://www.ebi.ac.uk/intact/interactors/id:P14753*" }, { "database": "iPTMnet", "id": "P14753", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P14753" }, { "database": "PubMed", "id": "9573010", "url": "https://pubmed.ncbi.nlm.nih.gov/9573010" }, { "database": "PubMed", "id": "7559499", "url": "https://pubmed.ncbi.nlm.nih.gov/7559499" }, { "database": "PubMed", "id": "8639815", "url": "https://pubmed.ncbi.nlm.nih.gov/8639815" } ], "site_lbl": "Tyr503", "uniprot_canonical_ac": "P14753-1" } ], "record_id": "pubmed.9573010", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 9 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": 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"o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Fibroblast growth factor receptor 1 is fused to FIM in stem-cell myeloproliferative disorder with t(8;13).", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "1998", "authors": "Popovici C, Adelaide J, Ollendorff V, Chaffanet M, Guasch G, Jacrot M, Leroux D, Birnbaum D, Pebusque MJ", "reference": { "type": "PubMed", "id": "9576949", "url": "https://pubmed.ncbi.nlm.nih.gov/9576949" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P42229-1", "protein_name": "Signal transducer and activator of transcription 5A", "gene_name": "STAT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95684-1", "protein_name": "Centrosomal protein 43", "gene_name": "CEP43", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51692-1", "protein_name": "Signal transducer and activator of transcription 5B", "gene_name": "STAT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92614-1", "protein_name": "Unconventional myosin-XVIIIa", "gene_name": "MYO18A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11274-1", "protein_name": "Breakpoint cluster region protein", "gene_name": "BCR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16630-1", "protein_name": "Cleavage and polyadenylation specificity factor subunit 6", "gene_name": "CPSF6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P39880-1", "protein_name": "Homeobox protein cut-like 1", "gene_name": "CUX1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40763-1", "protein_name": "Signal transducer and activator of transcription 3", "gene_name": "STAT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBW7-1", "protein_name": "Zinc finger MYM-type protein 2", "gene_name": "ZMYM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NVK5-1", "protein_name": "FGFR1 oncogene partner 2", "gene_name": "FGFR1OP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42224-1", "protein_name": "Signal transducer and activator of transcription 1-alpha/beta", "gene_name": "STAT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15164-1", "protein_name": "Transcription intermediary factor 1-alpha", "gene_name": "TRIM24", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q32MZ4-1", "protein_name": "Leucine-rich repeat flightless-interacting protein 1", "gene_name": "LRRFIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQC2-1", "protein_name": "GRB2-associated-binding protein 2", "gene_name": "GAB2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P42229", "url": "https://www.uniprot.org/uniprotkb/P42229" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.9576949", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { 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"field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Regulation of both erythroid and megakaryocytic differentiation of a human leukemia cell line, UT-7.", "journal": "Acta haematologica", "date": "1998", "authors": "Miura Y, Kirito K, Komatsu N", "reference": { "type": "PubMed", "id": "9587401", "url": "https://pubmed.ncbi.nlm.nih.gov/9587401" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P42229-1", "protein_name": "Signal transducer and activator of transcription 5A", "gene_name": "STAT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51692-1", "protein_name": "Signal transducer and activator of transcription 5B", "gene_name": "STAT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60674-1", "protein_name": "Tyrosine-protein kinase JAK2", "gene_name": "JAK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19235-1", "protein_name": "Erythropoietin receptor", "gene_name": "EPOR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y4H2-1", "protein_name": "Insulin receptor substrate 2", "gene_name": "IRS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07948-1", "protein_name": "Tyrosine-protein kinase Lyn", "gene_name": "LYN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01588-1", "protein_name": "Erythropoietin", "gene_name": "EPO", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": 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"count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Enhancing leptin response by preventing SH2-containing phosphatase 2 interaction with Ob receptor.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "1998", "authors": "Carpenter LR, Farruggella TJ, Symes A, Karow ML, Yancopoulos GD, Stahl N", "reference": { "type": "PubMed", "id": "9600917", "url": "https://pubmed.ncbi.nlm.nih.gov/9600917" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P42229-1", "protein_name": "Signal transducer and activator of transcription 5A", "gene_name": "STAT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51692-1", "protein_name": "Signal transducer and activator of transcription 5B", "gene_name": "STAT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60674-1", "protein_name": "Tyrosine-protein kinase JAK2", "gene_name": "JAK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41159-1", "protein_name": "Leptin", "gene_name": "LEP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y4H2-1", "protein_name": "Insulin receptor substrate 2", "gene_name": "IRS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06124-2", "protein_name": "Tyrosine-protein phosphatase non-receptor type 11", "gene_name": "PTPN11", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14543-1", "protein_name": "Suppressor of cytokine signaling 3", "gene_name": "SOCS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40763-1", "protein_name": "Signal transducer and activator of transcription 3", "gene_name": "STAT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P48357-1", "protein_name": "Leptin receptor", "gene_name": "LEPR", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P42229", "url": "https://www.uniprot.org/uniprotkb/P42229" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 1078, "end_pos": 1079, "sequence_org": "YY", "sequence_mut": "FF", "comment": "No effect on PTPN11 nor STAT3 phosphorylation.", "evidence": [ { "database": "UniProtKB", "id": "P48357", "url": "https://www.uniprot.org/uniprotkb/P48357" }, { "database": "PubMed", "id": "9600917", "url": "https://pubmed.ncbi.nlm.nih.gov/9600917" } ], "uniprot_canonical_ac": "P48357-1" }, { "start_pos": 1141, "end_pos": 1141, "sequence_org": "Y", "sequence_mut": "F", "comment": "No effect on PTPN11 phosphorylation; no STAT3 phosphorylation.", "evidence": [ { "database": "UniProtKB", "id": "P48357", "url": "https://www.uniprot.org/uniprotkb/P48357" }, { "database": "PubMed", "id": "9600917", "url": "https://pubmed.ncbi.nlm.nih.gov/9600917" } ], "uniprot_canonical_ac": "P48357-1" }, { "start_pos": 986, "end_pos": 986, "sequence_org": "Y", "sequence_mut": "F", "comment": "Greatly reduced PTPN11 binding; no PTPN11 phosphorylation; no effect on STAT3 phosphorylation.", "evidence": [ { "database": "UniProtKB", "id": "P48357", "url": "https://www.uniprot.org/uniprotkb/P48357" }, { "database": "PubMed", "id": "9600917", "url": "https://pubmed.ncbi.nlm.nih.gov/9600917" } ], "uniprot_canonical_ac": "P48357-1" } ], "phosphorylation": [ { "start_pos": 986, "end_pos": 986, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by JAK2", "evidence": [ { "database": "UniProtKB", "id": "P48357", "url": "https://www.uniprot.org/uniprotkb/P48357" }, { "database": "iPTMnet", "id": "P48357", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48357" }, { "database": "PubMed", "id": "10449753", "url": "https://pubmed.ncbi.nlm.nih.gov/10449753" }, { "database": "IntAct", "id": "P48357", "url": "https://www.ebi.ac.uk/intact/interactors/id:P48357*" }, { "database": "PubMed", "id": "11342028", "url": 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} ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Erythropoietin induces tyrosine phosphorylation of Jak2, STAT5A, and STAT5B in primary cultured human erythroid precursors.", "journal": "Blood", "date": "1998", "authors": "Oda A, Sawada K, Druker BJ, Ozaki K, Takano H, Koizumi K, Fukada Y, Handa M, Koike T, Ikeda Y", "reference": { "type": "PubMed", "id": "9657743", "url": "https://pubmed.ncbi.nlm.nih.gov/9657743" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P42229-1", "protein_name": "Signal transducer and activator of transcription 5A", "gene_name": "STAT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51692-1", "protein_name": "Signal transducer and activator of transcription 5B", "gene_name": "STAT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60674-1", "protein_name": "Tyrosine-protein kinase JAK2", "gene_name": "JAK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19235-1", "protein_name": "Erythropoietin receptor", "gene_name": "EPOR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y4H2-1", "protein_name": "Insulin receptor substrate 2", "gene_name": "IRS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07948-1", "protein_name": "Tyrosine-protein kinase Lyn", "gene_name": "LYN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01588-1", "protein_name": "Erythropoietin", "gene_name": "EPO", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P42229", "url": "https://www.uniprot.org/uniprotkb/P42229" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.9657743", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 7 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "In vitro interaction between STAT 5 and JAK 2; dependence upon phosphorylation status of STAT 5 and JAK 2.", "journal": "Molecular and cellular endocrinology", "date": "1998", "authors": "Flores-Morales A, Pircher TJ, Silvennoinen O, Gustafsson JA, Sanchez-Gomez M, Norstedt G, Haldosen LA, Wood TJ", "reference": { "type": "PubMed", "id": "9685210", "url": "https://pubmed.ncbi.nlm.nih.gov/9685210" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P42229-1", "protein_name": 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"protein_name": "Interleukin-5", "gene_name": "IL5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29350-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 6", "gene_name": "PTPN6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04141-1", "protein_name": "Granulocyte-macrophage colony-stimulating factor", "gene_name": "CSF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P32927-1", "protein_name": "Cytokine receptor common subunit beta", "gene_name": "CSF2RB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P17612-1", "protein_name": "cAMP-dependent protein kinase catalytic subunit alpha", "gene_name": "PRKACA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92569-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit gamma", "gene_name": "PIK3R3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06124-2", "protein_name": "Tyrosine-protein phosphatase non-receptor type 11", "gene_name": "PTPN11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15509-1", "protein_name": "Granulocyte-macrophage colony-stimulating factor receptor subunit alpha", "gene_name": "CSF2RA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42680-1", "protein_name": "Tyrosine-protein kinase Tec", "gene_name": "TEC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00329-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform", "gene_name": "PIK3CD", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29353-1", "protein_name": "SHC-transforming protein 1", "gene_name": "SHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63104-1", "protein_name": "14-3-3 protein zeta/delta", "gene_name": "YWHAZ", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15498-1", "protein_name": "Proto-oncogene vav", "gene_name": "VAV1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P42229", "url": "https://www.uniprot.org/uniprotkb/P42229" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.9685210", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 23 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Characterization of cytokine differential induction of STAT complexes in primary human T and NK cells.", "journal": "Journal of leukocyte biology", "date": "1998", "authors": "Yu CR, Young HA, Ortaldo JR", "reference": { "type": "PubMed", "id": "9715265", "url": "https://pubmed.ncbi.nlm.nih.gov/9715265" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P42229-1", "protein_name": "Signal transducer and activator of transcription 5A", "gene_name": "STAT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51532-1", "protein_name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4", "gene_name": "SMARCA4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15524-1", "protein_name": "Suppressor of cytokine signaling 1", "gene_name": "SOCS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51692-1", "protein_name": "Signal transducer and activator of transcription 5B", "gene_name": "STAT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P13232-1", "protein_name": "Interleukin-7", "gene_name": "IL7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16871-1", "protein_name": "Interleukin-7 receptor subunit alpha", "gene_name": "IL7R", "tax_name": "Human" }, { "uniprot_canonical_ac": "P31785-1", "protein_name": "Cytokine receptor common subunit gamma", "gene_name": "IL2RG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NSE2-1", "protein_name": "Cytokine-inducible SH2-containing protein", "gene_name": "CISH", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14508-1", "protein_name": "Suppressor of cytokine signaling 2", "gene_name": "SOCS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52333-1", "protein_name": "Tyrosine-protein kinase JAK3", "gene_name": "JAK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HC73-1", "protein_name": "Cytokine receptor-like factor 2", "gene_name": "CRLF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y4H2-1", "protein_name": "Insulin receptor substrate 2", "gene_name": "IRS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68431-1", "protein_name": "Histone H3.1", "gene_name": "H3C10; H3C11; H3C12; H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92569-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit gamma", "gene_name": "PIK3R3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q969D9-1", "protein_name": "Thymic stromal lymphopoietin", "gene_name": "TSLP", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14210-1", "protein_name": "Hepatocyte growth factor", "gene_name": "HGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40763-1", "protein_name": "Signal transducer and activator of transcription 3", "gene_name": "STAT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q71DI3-1", "protein_name": "Histone H3.2", "gene_name": "H3C13; H3C14; H3C15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NSI6-1", "protein_name": "Bromodomain and WD repeat-containing protein 1", "gene_name": "BRWD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15918-1", "protein_name": "V(D)J recombination-activating protein 1", "gene_name": "RAG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P55895-1", "protein_name": "V(D)J recombination-activating protein 2", "gene_name": "RAG2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23458-1", "protein_name": "Tyrosine-protein kinase JAK1", "gene_name": "JAK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P42229", "url": "https://www.uniprot.org/uniprotkb/P42229" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.9715265", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 25 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { 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"protein_name": "Homeobox protein cut-like 1", "gene_name": "CUX1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11362-1", "protein_name": "Fibroblast growth factor receptor 1", "gene_name": "FGFR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40763-1", "protein_name": "Signal transducer and activator of transcription 3", "gene_name": "STAT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBW7-1", "protein_name": "Zinc finger MYM-type protein 2", "gene_name": "ZMYM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NVK5-1", "protein_name": "FGFR1 oncogene partner 2", "gene_name": "FGFR1OP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42224-1", "protein_name": "Signal transducer and activator of transcription 1-alpha/beta", "gene_name": "STAT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15164-1", "protein_name": "Transcription intermediary factor 1-alpha", "gene_name": "TRIM24", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q32MZ4-1", "protein_name": "Leucine-rich repeat flightless-interacting protein 1", "gene_name": "LRRFIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQC2-1", "protein_name": "GRB2-associated-binding protein 2", "gene_name": "GAB2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P42229", "url": "https://www.uniprot.org/uniprotkb/P42229" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.9716603", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 17 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Insulin-like growth factor-I augments erythropoietin-induced proliferation through enhanced tyrosine phosphorylation of STAT5.", "journal": "The Journal of biological chemistry", "date": "1998", "authors": "Okajima Y, Matsumura I, Nishiura T, Hashimoto K, Yoshida H, Ishikawa J, Wakao H, Yoshimura A, Kanakura Y, Tomiyama Y, Matsuzawa Y", "reference": { "type": "PubMed", "id": "9722506", "url": "https://pubmed.ncbi.nlm.nih.gov/9722506" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P42229-1", 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"p85 subunit of PI3 kinase does not bind to human Flt3 receptor, but associates with SHP2, SHIP, and a tyrosine-phosphorylated 100-kDa protein in Flt3 ligand-stimulated hematopoietic cells.", "journal": "Biochemical and biophysical research communications", "date": "1999", "authors": "Zhang S, Broxmeyer HE", "reference": { "type": "PubMed", "id": "9918857", "url": "https://pubmed.ncbi.nlm.nih.gov/9918857" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P42229-1", "protein_name": "Signal transducer and activator of transcription 5A", "gene_name": "STAT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y243-1", "protein_name": "RAC-gamma serine/threonine-protein kinase", "gene_name": "AKT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01112-1", "protein_name": "GTPase HRas", "gene_name": "HRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49771-1", "protein_name": "Fms-related tyrosine kinase 3 ligand", "gene_name": "FLT3LG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51692-1", "protein_name": "Signal transducer and activator of transcription 5B", "gene_name": "STAT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14789-1", "protein_name": "Golgin subfamily B member 1", "gene_name": "GOLGB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92614-1", "protein_name": "Unconventional myosin-XVIIIa", "gene_name": "MYO18A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01111-1", "protein_name": "GTPase NRas", "gene_name": "NRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11309-1", "protein_name": "Serine/threonine-protein kinase pim-1", "gene_name": "PIM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01082-1", "protein_name": "Spectrin beta chain, non-erythrocytic 1", "gene_name": "SPTBN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75791-1", "protein_name": "GRB2-related adapter protein 2", "gene_name": "GRAP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43521-1", "protein_name": "Bcl-2-like protein 11", "gene_name": "BCL2L11", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NPH5-1", "protein_name": "NADPH oxidase 4", "gene_name": "NOX4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07889-1", "protein_name": "Son of sevenless homolog 1", "gene_name": "SOS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43524-1", "protein_name": "Forkhead box protein O3", "gene_name": "FOXO3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P31749-1", "protein_name": "RAC-alpha serine/threonine-protein kinase", "gene_name": "AKT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41212-1", "protein_name": "Transcription factor ETV6", "gene_name": "ETV6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P31751-1", "protein_name": "RAC-beta 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receptor-interacting protein 11", "gene_name": "TRIP11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62993-1", "protein_name": "Growth factor receptor-bound protein 2", "gene_name": "GRB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQC2-1", "protein_name": "GRB2-associated-binding protein 2", "gene_name": "GAB2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P42229", "url": "https://www.uniprot.org/uniprotkb/P42229" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.9918857", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 29 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "A human erythropoietin receptor gene mutant causing familial erythrocytosis is associated with deregulation of the rates of Jak2 and Stat5 inactivation.", "journal": "Experimental hematology", "date": "1999", "authors": "Arcasoy MO, Harris KW, Forget BG", "reference": { "type": "PubMed", "id": "9923445", "url": "https://pubmed.ncbi.nlm.nih.gov/9923445" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P42229-1", "protein_name": "Signal transducer and activator of transcription 5A", "gene_name": "STAT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51692-1", "protein_name": "Signal transducer and activator of transcription 5B", "gene_name": "STAT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60674-1", "protein_name": "Tyrosine-protein kinase JAK2", "gene_name": "JAK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19235-1", "protein_name": "Erythropoietin receptor", "gene_name": "EPOR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y4H2-1", "protein_name": "Insulin receptor substrate 2", "gene_name": "IRS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07948-1", "protein_name": "Tyrosine-protein kinase Lyn", "gene_name": "LYN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01588-1", "protein_name": "Erythropoietin", "gene_name": "EPO", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P42229", "url": "https://www.uniprot.org/uniprotkb/P42229" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.9923445", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 7 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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"The t(6;8)(q27;p11) translocation in a stem cell myeloproliferative disorder fuses a novel gene, FOP, to fibroblast growth factor receptor 1.", "journal": "Blood", "date": "1999", "authors": "Popovici C, Zhang B, Gregoire MJ, Jonveaux P, Lafage-Pochitaloff M, Birnbaum D, Pebusque MJ", "reference": { "type": "PubMed", "id": "9949182", "url": "https://pubmed.ncbi.nlm.nih.gov/9949182" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P42229-1", "protein_name": "Signal transducer and activator of transcription 5A", "gene_name": "STAT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95684-1", "protein_name": "Centrosomal protein 43", "gene_name": "CEP43", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51692-1", "protein_name": "Signal transducer and activator of transcription 5B", "gene_name": "STAT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92614-1", "protein_name": "Unconventional myosin-XVIIIa", "gene_name": "MYO18A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11274-1", "protein_name": "Breakpoint cluster region protein", "gene_name": "BCR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16630-1", "protein_name": "Cleavage and polyadenylation specificity factor subunit 6", "gene_name": "CPSF6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P39880-1", "protein_name": "Homeobox protein cut-like 1", "gene_name": "CUX1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11362-1", "protein_name": "Fibroblast growth factor receptor 1", "gene_name": "FGFR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40763-1", "protein_name": "Signal transducer and activator of transcription 3", "gene_name": "STAT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBW7-1", "protein_name": "Zinc finger MYM-type protein 2", "gene_name": "ZMYM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NVK5-1", "protein_name": "FGFR1 oncogene partner 2", "gene_name": "FGFR1OP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42224-1", "protein_name": "Signal transducer and activator of transcription 1-alpha/beta", "gene_name": "STAT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15164-1", "protein_name": "Transcription intermediary factor 1-alpha", "gene_name": "TRIM24", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q32MZ4-1", "protein_name": "Leucine-rich repeat flightless-interacting protein 1", "gene_name": "LRRFIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQC2-1", "protein_name": "GRB2-associated-binding protein 2", "gene_name": "GAB2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P42229", "url": "https://www.uniprot.org/uniprotkb/P42229" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.9949182", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 17 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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"Architecture of TAF11/TAF13/TBP complex suggests novel regulation properties of general transcription factor TFIID.", "journal": "eLife", "date": "2017", "authors": "Gupta K, Watson AA, Baptista T, Scheer E, Chambers AL, Koehler C, Zou J, Obong-Ebong I, Kandiah E, Temblador A, Round A, Forest E, Man P, Bieniossek C, Laue ED, Lemke EA, Rappsilber J, Robinson CV, Devys D, Tora L, Berger I", "reference": { "type": "PubMed", "id": "29111974", "url": "https://pubmed.ncbi.nlm.nih.gov/29111974" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q15544-1", "protein_name": "Transcription initiation factor TFIID subunit 11", "gene_name": "TAF11", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15543-1", "protein_name": "Transcription initiation factor TFIID subunit 13", "gene_name": "TAF13", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q15544", "url": "https://www.uniprot.org/uniprotkb/Q15544" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.29111974", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], 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hTAFII20 and hTAFII28: three subunits of the human transcription factor TFIID.", "journal": "EMBO J.", "date": "1995", "authors": "Mengus G, May M, Jacq X, Staub A, Tora L, Chambon P, Davidson I", "reference": { "type": "PubMed", "id": "7729427", "url": "https://pubmed.ncbi.nlm.nih.gov/7729427" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q15544-1", "protein_name": "Transcription initiation factor TFIID subunit 11", "gene_name": "TAF11", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15543-1", "protein_name": "Transcription initiation factor TFIID subunit 13", "gene_name": "TAF13", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16514-1", "protein_name": "Transcription initiation factor TFIID subunit 12", "gene_name": "TAF12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12962-1", "protein_name": "Transcription initiation factor TFIID subunit 10", "gene_name": "TAF10", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q15544", "url": "https://www.uniprot.org/uniprotkb/Q15544" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.7729427", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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[] } ] }, { "title": "Isolation and characterization of a cDNA encoding a human TFIID subunit containing a variety of putative structural motifs including direct repeats.", "journal": "Biol. Pharm. Bull.", "date": "1996", "authors": "Kuzuhara T, Horikoshi M", "reference": { "type": "PubMed", "id": "8820923", "url": "https://pubmed.ncbi.nlm.nih.gov/8820923" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q15544-1", "protein_name": "Transcription initiation factor TFIID subunit 11", "gene_name": "TAF11", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q15544", "url": "https://www.uniprot.org/uniprotkb/Q15544" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.8820923", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", 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"glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Human TAF(II)28 and TAF(II)18 interact through a histone fold encoded by atypical evolutionary conserved motifs also found in the SPT3 family.", "journal": "Cell", "date": "1998", "authors": "Birck C, Poch O, Romier C, Ruff M, Mengus G, Lavigne AC, Davidson I, Moras D", "reference": { "type": "PubMed", "id": "9695952", "url": "https://pubmed.ncbi.nlm.nih.gov/9695952" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q15544-1", "protein_name": "Transcription initiation factor TFIID subunit 11", "gene_name": 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"uniprot_canonical_ac": "Q03761-1", "protein_name": "SAGA complex/transcription factor TFIID complex subunit TAF12", "gene_name": "TAF12", "tax_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P11747-1", "protein_name": "Transcription initiation factor TFIID subunit 13", "gene_name": "TAF13", "tax_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q04226-1", "protein_name": "Transcription initiation factor TFIID subunit 11", "gene_name": "TAF11", "tax_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q12030-1", "protein_name": "SAGA complex/transcription factor TFIID complex subunit TAF10", "gene_name": "TAF10", "tax_name": "Baker's yeast" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q15544", "url": "https://www.uniprot.org/uniprotkb/Q15544" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.9695952", "abstract": "", "glycosylation": [], 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{ "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Human wig-1, a p53 target gene that encodes a growth inhibitory zinc finger protein.", "journal": "Oncogene", "date": "2001-09-06", "authors": "Hellborg F, Qian W, Mendez-Vidal C, Asker C, Kost-Alimova M, Wilhelm M, Imreh S, Wiman K G", "reference": { "type": "PubMed", "id": "11571644", 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splicing regulator that inhibits the splicing of oncogenic CD44 variants in colorectal carcinoma.", "journal": "Genes & development", "date": "2021", "authors": "Muys BR, Anastasakis DG, Claypool D, Pongor L, Li XL, Grammatikakis I, Liu M, Wang X, Prasanth KV, Aladjem MI, Lal A, Hafner M", "reference": { "type": "PubMed", "id": "33334821", "url": "https://pubmed.ncbi.nlm.nih.gov/33334821" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9HA38-1", "protein_name": "Zinc finger matrin-type protein 3", "gene_name": "ZMAT3", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9HA38", "url": "https://www.uniprot.org/uniprotkb/Q9HA38" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.33334821", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], 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"table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Structure of a Ran-binding domain complexed with Ran bound to a GTP analogue: implications for nuclear transport.", "journal": "Nature", "date": "1999", "authors": "Vetter IR, Nowak C, Nishimoto T, Kuhlmann J, Wittinghofer A", "reference": { "type": "PubMed", "id": "10078529", "url": "https://pubmed.ncbi.nlm.nih.gov/10078529" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P62826-1", "protein_name": "GTP-binding nuclear protein Ran", "gene_name": "RAN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49792-1", "protein_name": "E3 SUMO-protein ligase RanBP2", "gene_name": "RANBP2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P62826", "url": "https://www.uniprot.org/uniprotkb/P62826" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.10078529", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "CRM1-mediated recycling of snurportin 1 to the cytoplasm.", "journal": "J. Cell Biol.", "date": "1999", "authors": "Paraskeva E, Izaurralde E, Bischoff FR, Huber J, Kutay U, Hartmann E, Luhrmann R, Gorlich D", "reference": { "type": "PubMed", "id": "10209022", "url": "https://pubmed.ncbi.nlm.nih.gov/10209022" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P62826-1", "protein_name": "GTP-binding nuclear protein Ran", "gene_name": "RAN", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95149-1", "protein_name": "Snurportin-1", "gene_name": "SNUPN", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14980-1", "protein_name": "Exportin-1", "gene_name": "XPO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95373-1", "protein_name": "Importin-7", "gene_name": "IPO7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14974-1", "protein_name": "Importin subunit beta-1", "gene_name": "KPNB1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P62826", "url": "https://www.uniprot.org/uniprotkb/P62826" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.10209022", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Structure of the nuclear transport complex karyopherin-beta2-Ran x GppNHp.", "journal": "Nature", "date": "1999", "authors": "Chook YM, Blobel G", "reference": { "type": "PubMed", "id": "10353245", "url": "https://pubmed.ncbi.nlm.nih.gov/10353245" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P62826-1", "protein_name": "GTP-binding nuclear protein Ran", "gene_name": "RAN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92973-1", "protein_name": "Transportin-1", "gene_name": "TNPO1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P62826", "url": "https://www.uniprot.org/uniprotkb/P62826" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.10353245", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Structural view of the Ran-Importin beta interaction at 2.3 A resolution.", "journal": "Cell", "date": "1999", "authors": "Vetter IR, Arndt A, Kutay U, Gorlich D, Wittinghofer A", "reference": { "type": "PubMed", "id": "10367892", "url": "https://pubmed.ncbi.nlm.nih.gov/10367892" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P62826-1", "protein_name": "GTP-binding nuclear protein Ran", "gene_name": "RAN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14974-1", "protein_name": "Importin subunit beta-1", "gene_name": "KPNB1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P62826", "url": "https://www.uniprot.org/uniprotkb/P62826" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.10367892", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { 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"field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The linkage of Kennedy's neuron disease to ARA24, the first identified androgen receptor polyglutamine region-associated coactivator.", "journal": "The Journal of biological chemistry", "date": "1999-07-16", "authors": "Hsiao P W, Lin D L, Nakao R, Chang C", "reference": { "type": "PubMed", "id": "10400640", "url": "https://pubmed.ncbi.nlm.nih.gov/10400640" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P62826-1", "protein_name": "GTP-binding nuclear protein Ran", "gene_name": "RAN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10275-1", "protein_name": "Androgen receptor", "gene_name": "AR", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P62826", "url": "https://www.uniprot.org/uniprotkb/P62826" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.10400640", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 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"o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Generation of GTP-bound Ran by RCC1 is required 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Decreases nuclear import of proteins and RNA. Stabilizes the interaction with RCC1. No effect on nuclear location during interphase. Loss of activity in triggering microtubule assembly at mitotic chromosomes.", "evidence": [ { "database": "UniProtKB", "id": "P62826", "url": "https://www.uniprot.org/uniprotkb/P62826" }, { "database": "PubMed", "id": "10408446", "url": "https://pubmed.ncbi.nlm.nih.gov/10408446" }, { "database": "PubMed", "id": "9351834", "url": "https://pubmed.ncbi.nlm.nih.gov/9351834" }, { "database": "PubMed", "id": "7819259", "url": "https://pubmed.ncbi.nlm.nih.gov/7819259" }, { "database": "PubMed", "id": "12194828", "url": "https://pubmed.ncbi.nlm.nih.gov/12194828" }, { "database": "PubMed", "id": "8636225", "url": "https://pubmed.ncbi.nlm.nih.gov/8636225" } ], "uniprot_canonical_ac": "P62826-1" }, { "start_pos": 69, "end_pos": 69, "sequence_org": "Q", "sequence_mut": "L", "comment": "Strongly decreased GTPase activity. Probably locked in the GTP-bound form. Loss of interaction with NUTF2. Decreases nuclear location and leads to cytoplasmic location during interphase. Loss of function in importin-mediated protein nuclear import. High activity in triggering microtubule assembly at mitotic chromosomes. 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"date": "2000", "authors": "Neumann G, Hughes MT, Kawaoka Y", "reference": { "type": "PubMed", "id": "11118210", "url": "https://pubmed.ncbi.nlm.nih.gov/11118210" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P62826-1", "protein_name": "GTP-binding nuclear protein Ran", "gene_name": "RAN", "tax_name": "Human" }, { "uniprot_canonical_ac": "A8CG34-1", "protein_name": "Nuclear envelope pore membrane protein POM 121C", "gene_name": "POM121C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35658-1", "protein_name": "Nuclear pore complex protein Nup214", "gene_name": "NUP214", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92621-1", "protein_name": "Nuclear pore complex protein Nup205", "gene_name": "NUP205", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5SRE5-1", "protein_name": "Nucleoporin NUP188", "gene_name": "NUP188", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BW27-1", "protein_name": "Nuclear pore complex protein Nup85", "gene_name": "NUP85", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15504-1", "protein_name": "Nucleoporin NUP42", "gene_name": "NUP42", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKX7-1", "protein_name": "Nuclear pore complex protein Nup50", "gene_name": "NUP50", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57740-1", "protein_name": "Nuclear pore complex protein Nup107", "gene_name": "NUP107", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUM0-1", "protein_name": "Nuclear pore complex protein Nup133", "gene_name": "NUP133", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BTX1-1", "protein_name": "Nucleoporin NDC1", "gene_name": "NDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH3-1", "protein_name": "Nucleoporin Nup43", "gene_name": "NUP43", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TEM1-1", "protein_name": "Nuclear pore membrane glycoprotein 210", "gene_name": "NUP210", "tax_name": "Human" }, { "uniprot_canonical_ac": "P55735-1", "protein_name": "Protein SEC13 homolog", "gene_name": "SEC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75694-1", "protein_name": "Nuclear pore complex protein Nup155", "gene_name": "NUP155", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH5-1", "protein_name": "Nucleoporin NUP35", "gene_name": "NUP35", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14980-1", "protein_name": "Exportin-1", "gene_name": "XPO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96HA1-1", "protein_name": "Nuclear envelope pore membrane protein POM 121", "gene_name": "POM121", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49790-1", "protein_name": "Nuclear pore complex protein Nup153", "gene_name": "NUP153", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12769-1", "protein_name": "Nuclear pore complex protein Nup160", "gene_name": "NUP160", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49792-1", "protein_name": "E3 SUMO-protein ligase RanBP2", "gene_name": "RANBP2", 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"o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "A role for the basic patch and the C terminus of RanGTP in regulating the dynamic interactions with importin beta, CRM1 and RanBP1.", "journal": "Journal of molecular biology", "date": "2001", "authors": "Nilsson J, Askjaer P, Kjems J", "reference": { "type": "PubMed", "id": "11124902", "url": "https://pubmed.ncbi.nlm.nih.gov/11124902" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P62826-1", "protein_name": "GTP-binding nuclear protein Ran", "gene_name": "RAN", "tax_name": "Human" }, { "uniprot_canonical_ac": "A8CG34-1", "protein_name": "Nuclear envelope pore membrane protein POM 121C", "gene_name": "POM121C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35658-1", "protein_name": "Nuclear pore complex protein Nup214", "gene_name": "NUP214", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92621-1", "protein_name": "Nuclear pore complex protein Nup205", "gene_name": 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"NUP93", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z3B4-1", "protein_name": "Nucleoporin p54", "gene_name": "NUP54", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12270-1", "protein_name": "Nucleoprotein TPR", "gene_name": "TPR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NRG9-1", "protein_name": "Aladin", "gene_name": "AAAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37198-1", "protein_name": "Nuclear pore glycoprotein p62", "gene_name": "NUP62", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P62826", "url": "https://www.uniprot.org/uniprotkb/P62826" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.11231581", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 29 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", 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}, { "uniprot_canonical_ac": "P57740-1", "protein_name": "Nuclear pore complex protein Nup107", "gene_name": "NUP107", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUM0-1", "protein_name": "Nuclear pore complex protein Nup133", "gene_name": "NUP133", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BTX1-1", "protein_name": "Nucleoporin NDC1", "gene_name": "NDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH3-1", "protein_name": "Nucleoporin Nup43", "gene_name": "NUP43", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TEM1-1", "protein_name": "Nuclear pore membrane glycoprotein 210", "gene_name": "NUP210", "tax_name": "Human" }, { "uniprot_canonical_ac": "P55735-1", "protein_name": "Protein SEC13 homolog", "gene_name": "SEC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75694-1", "protein_name": "Nuclear pore complex protein Nup155", "gene_name": "NUP155", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH5-1", "protein_name": "Nucleoporin NUP35", "gene_name": "NUP35", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14980-1", "protein_name": "Exportin-1", "gene_name": "XPO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96HA1-1", "protein_name": "Nuclear envelope pore membrane protein POM 121", "gene_name": "POM121", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49790-1", "protein_name": "Nuclear pore complex protein Nup153", "gene_name": "NUP153", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12769-1", "protein_name": "Nuclear pore complex protein Nup160", "gene_name": "NUP160", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49792-1", "protein_name": "E3 SUMO-protein ligase RanBP2", "gene_name": "RANBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99567-1", "protein_name": "Nuclear pore complex protein Nup88", "gene_name": "NUP88", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78406-1", "protein_name": "mRNA export factor RAE1", "gene_name": "RAE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH4-1", "protein_name": "Nucleoporin Nup37", "gene_name": "NUP37", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N1F7-1", "protein_name": "Nuclear pore complex protein Nup93", "gene_name": "NUP93", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z3B4-1", "protein_name": "Nucleoporin p54", "gene_name": "NUP54", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12270-1", "protein_name": "Nucleoprotein TPR", "gene_name": "TPR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NRG9-1", "protein_name": "Aladin", "gene_name": "AAAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37198-1", "protein_name": "Nuclear pore glycoprotein p62", "gene_name": "NUP62", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P62826", "url": "https://www.uniprot.org/uniprotkb/P62826" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Ran-binding protein 3 is a cofactor for Crm1-mediated nuclear protein export.", "journal": "J. Cell Biol.", "date": "2001", "authors": "Lindsay ME, Holaska JM, Welch K, Paschal BM, Macara IG", "reference": { "type": "PubMed", "id": "11425870", "url": "https://pubmed.ncbi.nlm.nih.gov/11425870" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P62826-1", "protein_name": "GTP-binding nuclear protein Ran", "gene_name": "RAN", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14980-1", "protein_name": "Exportin-1", "gene_name": "XPO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H6Z4-1", "protein_name": "Ran-binding protein 3", "gene_name": "RANBP3", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P62826", "url": "https://www.uniprot.org/uniprotkb/P62826" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.11425870", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], 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}, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Inhibition of nuclear export of ribonucleoprotein complexes of influenza virus by leptomycin B.", "journal": "Virus research", "date": "2001", "authors": "Watanabe K, Takizawa N, Katoh M, Hoshida K, Kobayashi N, Nagata K", "reference": { "type": "PubMed", "id": "11451485", "url": "https://pubmed.ncbi.nlm.nih.gov/11451485" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P62826-1", "protein_name": "GTP-binding nuclear protein Ran", "gene_name": "RAN", "tax_name": "Human" }, { "uniprot_canonical_ac": "A8CG34-1", "protein_name": "Nuclear envelope pore membrane protein POM 121C", "gene_name": "POM121C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35658-1", "protein_name": "Nuclear pore complex protein Nup214", "gene_name": "NUP214", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92621-1", "protein_name": "Nuclear pore complex protein Nup205", "gene_name": "NUP205", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5SRE5-1", "protein_name": "Nucleoporin NUP188", "gene_name": "NUP188", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BW27-1", "protein_name": "Nuclear pore complex protein Nup85", "gene_name": "NUP85", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15504-1", "protein_name": "Nucleoporin NUP42", "gene_name": "NUP42", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKX7-1", "protein_name": "Nuclear pore complex protein Nup50", "gene_name": "NUP50", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57740-1", "protein_name": "Nuclear pore complex protein Nup107", "gene_name": "NUP107", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUM0-1", "protein_name": "Nuclear pore complex protein Nup133", "gene_name": "NUP133", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BTX1-1", "protein_name": "Nucleoporin NDC1", "gene_name": "NDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH3-1", "protein_name": "Nucleoporin Nup43", "gene_name": "NUP43", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TEM1-1", "protein_name": "Nuclear pore membrane glycoprotein 210", "gene_name": "NUP210", "tax_name": "Human" }, { "uniprot_canonical_ac": "P55735-1", "protein_name": "Protein SEC13 homolog", "gene_name": "SEC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75694-1", "protein_name": "Nuclear pore complex protein Nup155", "gene_name": "NUP155", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH5-1", "protein_name": "Nucleoporin NUP35", "gene_name": "NUP35", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14980-1", "protein_name": "Exportin-1", "gene_name": "XPO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96HA1-1", "protein_name": "Nuclear envelope pore membrane protein POM 121", "gene_name": "POM121", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49790-1", "protein_name": "Nuclear pore complex protein Nup153", "gene_name": "NUP153", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12769-1", "protein_name": "Nuclear pore complex protein Nup160", "gene_name": "NUP160", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49792-1", "protein_name": "E3 SUMO-protein ligase RanBP2", "gene_name": "RANBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99567-1", "protein_name": "Nuclear pore complex protein Nup88", "gene_name": "NUP88", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78406-1", "protein_name": "mRNA export factor RAE1", "gene_name": "RAE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH4-1", "protein_name": "Nucleoporin Nup37", "gene_name": "NUP37", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N1F7-1", "protein_name": "Nuclear pore complex protein Nup93", "gene_name": "NUP93", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z3B4-1", "protein_name": "Nucleoporin p54", "gene_name": "NUP54", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12270-1", "protein_name": "Nucleoprotein TPR", "gene_name": "TPR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NRG9-1", "protein_name": "Aladin", "gene_name": "AAAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37198-1", "protein_name": "Nuclear pore glycoprotein p62", "gene_name": "NUP62", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P62826", "url": "https://www.uniprot.org/uniprotkb/P62826" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.11451485", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 29 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "RanBP3 influences interactions between CRM1 and its nuclear protein export substrates.", "journal": "EMBO Rep.", "date": "2001", "authors": "Englmeier L, Fornerod M, Bischoff FR, Petosa C, Mattaj IW, Kutay U", "reference": { "type": "PubMed", "id": "11571268", "url": "https://pubmed.ncbi.nlm.nih.gov/11571268" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P62826-1", "protein_name": "GTP-binding nuclear protein Ran", "gene_name": "RAN", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14980-1", "protein_name": "Exportin-1", "gene_name": "XPO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H6Z4-1", "protein_name": "Ran-binding protein 3", "gene_name": "RANBP3", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P62826", "url": "https://www.uniprot.org/uniprotkb/P62826" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.11571268", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "RanGAP mediates GTP hydrolysis without an arginine finger.", "journal": "Nature", "date": "2002", "authors": "Seewald MJ, Korner C, Wittinghofer A, Vetter IR", "reference": { "type": "PubMed", "id": "11832950", "url": "https://pubmed.ncbi.nlm.nih.gov/11832950" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P62826-1", "protein_name": "GTP-binding nuclear protein Ran", "gene_name": "RAN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P43487-1", "protein_name": "Ran-specific GTPase-activating protein", "gene_name": "RANBP1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P62826", "url": "https://www.uniprot.org/uniprotkb/P62826" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.11832950", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Recruitment of the Crm1 nuclear export factor is sufficient to induce cytoplasmic expression of incompletely spliced human immunodeficiency virus mRNAs.", "journal": "Journal of virology", "date": "2002", "authors": "Yi R, Bogerd HP, Cullen BR", "reference": { "type": "PubMed", "id": "11836381", "url": "https://pubmed.ncbi.nlm.nih.gov/11836381" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P62826-1", "protein_name": "GTP-binding nuclear protein Ran", "gene_name": "RAN", "tax_name": "Human" }, { 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"Nuclear pore complex protein Nup107", "gene_name": "NUP107", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUM0-1", "protein_name": "Nuclear pore complex protein Nup133", "gene_name": "NUP133", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BTX1-1", "protein_name": "Nucleoporin NDC1", "gene_name": "NDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH3-1", "protein_name": "Nucleoporin Nup43", "gene_name": "NUP43", "tax_name": "Human" }, { "uniprot_canonical_ac": "P18754-1", "protein_name": "Regulator of chromosome condensation", "gene_name": "RCC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TEM1-1", "protein_name": "Nuclear pore membrane glycoprotein 210", "gene_name": "NUP210", "tax_name": "Human" }, { "uniprot_canonical_ac": "P55735-1", "protein_name": "Protein SEC13 homolog", "gene_name": "SEC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75694-1", "protein_name": "Nuclear pore complex protein Nup155", "gene_name": "NUP155", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH5-1", "protein_name": "Nucleoporin NUP35", "gene_name": "NUP35", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14980-1", "protein_name": "Exportin-1", "gene_name": "XPO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96HA1-1", "protein_name": "Nuclear envelope pore membrane protein POM 121", "gene_name": "POM121", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49790-1", "protein_name": "Nuclear pore complex protein Nup153", "gene_name": "NUP153", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12769-1", "protein_name": "Nuclear pore complex protein Nup160", "gene_name": "NUP160", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49792-1", "protein_name": "E3 SUMO-protein ligase RanBP2", "gene_name": "RANBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99567-1", "protein_name": "Nuclear pore complex protein Nup88", "gene_name": "NUP88", "tax_name": "Human" }, { "uniprot_canonical_ac": "P43487-1", "protein_name": "Ran-specific GTPase-activating protein", "gene_name": "RANBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46060-1", "protein_name": "Ran GTPase-activating protein 1", "gene_name": "RANGAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78406-1", "protein_name": "mRNA export factor RAE1", "gene_name": "RAE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH4-1", "protein_name": "Nucleoporin Nup37", "gene_name": "NUP37", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N1F7-1", "protein_name": "Nuclear pore complex protein Nup93", "gene_name": "NUP93", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z3B4-1", "protein_name": "Nucleoporin p54", "gene_name": "NUP54", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12270-1", "protein_name": "Nucleoprotein TPR", "gene_name": "TPR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NRG9-1", "protein_name": "Aladin", "gene_name": "AAAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37198-1", "protein_name": "Nuclear pore glycoprotein p62", "gene_name": "NUP62", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P62826", "url": "https://www.uniprot.org/uniprotkb/P62826" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.11836381", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 32 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Ran-binding protein 3 links Crm1 to the Ran guanine nucleotide exchange factor.", "journal": "The Journal of biological chemistry", "date": "2002", "authors": "Nemergut ME, Lindsay ME, Brownawell AM, Macara IG", "reference": { "type": "PubMed", "id": "11932251", "url": "https://pubmed.ncbi.nlm.nih.gov/11932251" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P62826-1", "protein_name": "GTP-binding nuclear protein Ran", "gene_name": "RAN", "tax_name": "Human" }, { "uniprot_canonical_ac": "A8CG34-1", "protein_name": "Nuclear envelope pore membrane protein POM 121C", "gene_name": "POM121C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35658-1", "protein_name": "Nuclear pore complex protein Nup214", "gene_name": "NUP214", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92621-1", "protein_name": "Nuclear pore complex protein Nup205", "gene_name": "NUP205", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5SRE5-1", "protein_name": "Nucleoporin NUP188", "gene_name": "NUP188", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BW27-1", "protein_name": "Nuclear pore complex protein Nup85", "gene_name": "NUP85", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15504-1", "protein_name": "Nucleoporin NUP42", "gene_name": "NUP42", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKX7-1", "protein_name": "Nuclear pore complex protein Nup50", "gene_name": "NUP50", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57740-1", "protein_name": "Nuclear pore complex protein Nup107", "gene_name": "NUP107", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUM0-1", "protein_name": "Nuclear pore complex protein Nup133", "gene_name": "NUP133", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BTX1-1", "protein_name": "Nucleoporin NDC1", "gene_name": "NDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH3-1", "protein_name": "Nucleoporin Nup43", "gene_name": "NUP43", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TEM1-1", "protein_name": "Nuclear pore membrane glycoprotein 210", "gene_name": "NUP210", "tax_name": "Human" }, { "uniprot_canonical_ac": "P55735-1", "protein_name": "Protein SEC13 homolog", "gene_name": "SEC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75694-1", "protein_name": "Nuclear pore complex protein Nup155", "gene_name": "NUP155", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH5-1", "protein_name": "Nucleoporin NUP35", "gene_name": "NUP35", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14980-1", "protein_name": "Exportin-1", "gene_name": "XPO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96HA1-1", "protein_name": "Nuclear envelope pore membrane protein POM 121", "gene_name": "POM121", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49790-1", "protein_name": "Nuclear pore complex protein Nup153", "gene_name": "NUP153", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12769-1", "protein_name": "Nuclear pore complex protein Nup160", "gene_name": "NUP160", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49792-1", "protein_name": "E3 SUMO-protein ligase RanBP2", "gene_name": "RANBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99567-1", "protein_name": "Nuclear pore complex protein Nup88", "gene_name": "NUP88", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H6Z4-1", "protein_name": "Ran-binding protein 3", "gene_name": "RANBP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78406-1", "protein_name": "mRNA export factor RAE1", "gene_name": "RAE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH4-1", "protein_name": "Nucleoporin Nup37", "gene_name": "NUP37", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N1F7-1", "protein_name": "Nuclear pore complex protein Nup93", "gene_name": "NUP93", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z3B4-1", "protein_name": "Nucleoporin p54", "gene_name": "NUP54", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12270-1", "protein_name": "Nucleoprotein TPR", "gene_name": "TPR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NRG9-1", "protein_name": "Aladin", "gene_name": "AAAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37198-1", "protein_name": "Nuclear pore glycoprotein p62", "gene_name": "NUP62", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P62826", "url": "https://www.uniprot.org/uniprotkb/P62826" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.11932251", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 30 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Targeting of RCC1 to chromosomes is required for proper mitotic spindle assembly in human cells.", "journal": "Current biology : CB", "date": "2002", "authors": "Moore W, Zhang C, Clarke PR", "reference": { "type": "PubMed", "id": "12194828", "url": "https://pubmed.ncbi.nlm.nih.gov/12194828" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P62826-1", "protein_name": "GTP-binding nuclear protein Ran", "gene_name": "RAN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P18754-1", "protein_name": "Regulator of chromosome condensation", "gene_name": "RCC1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P62826", "url": "https://www.uniprot.org/uniprotkb/P62826" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 24, "end_pos": 24, "sequence_org": "T", "sequence_mut": "N", "comment": "Has low binding affinity for GTP and GDP. Decreases nuclear import of proteins and RNA. Stabilizes the interaction with RCC1. No effect on nuclear location during interphase. Loss of activity in triggering microtubule assembly at mitotic chromosomes.", "evidence": [ { "database": "UniProtKB", "id": "P62826", "url": "https://www.uniprot.org/uniprotkb/P62826" }, { "database": "PubMed", "id": "10408446", "url": "https://pubmed.ncbi.nlm.nih.gov/10408446" }, { "database": "PubMed", "id": "9351834", "url": "https://pubmed.ncbi.nlm.nih.gov/9351834" }, { "database": "PubMed", "id": "7819259", "url": "https://pubmed.ncbi.nlm.nih.gov/7819259" }, { "database": "PubMed", "id": "12194828", "url": "https://pubmed.ncbi.nlm.nih.gov/12194828" }, { "database": "PubMed", "id": "8636225", "url": "https://pubmed.ncbi.nlm.nih.gov/8636225" } ], "uniprot_canonical_ac": "P62826-1" }, { "start_pos": 69, "end_pos": 69, "sequence_org": "Q", "sequence_mut": "L", "comment": "Strongly decreased GTPase activity. Probably locked in the GTP-bound form. Loss of interaction with NUTF2. Decreases nuclear location and leads to cytoplasmic location during interphase. Loss of function in importin-mediated protein nuclear import. High activity in triggering microtubule assembly at mitotic chromosomes. Blocks DNA replication; when associated with V-19.", "evidence": [ { "database": "UniProtKB", "id": "P62826", "url": "https://www.uniprot.org/uniprotkb/P62826" }, { "database": "PubMed", "id": "8421051", "url": "https://pubmed.ncbi.nlm.nih.gov/8421051" }, { "database": "PubMed", "id": "9822603", "url": "https://pubmed.ncbi.nlm.nih.gov/9822603" }, { "database": "PubMed", "id": "17209048", "url": "https://pubmed.ncbi.nlm.nih.gov/17209048" }, { "database": "PubMed", "id": "10408446", "url": "https://pubmed.ncbi.nlm.nih.gov/10408446" }, { "database": "PubMed", "id": "9351834", "url": "https://pubmed.ncbi.nlm.nih.gov/9351834" }, { "database": "PubMed", "id": "7819259", "url": "https://pubmed.ncbi.nlm.nih.gov/7819259" }, { "database": "PubMed", "id": "12194828", "url": "https://pubmed.ncbi.nlm.nih.gov/12194828" }, { "database": "PubMed", "id": "18591255", "url": "https://pubmed.ncbi.nlm.nih.gov/18591255" }, { "database": "PubMed", "id": "8636225", "url": "https://pubmed.ncbi.nlm.nih.gov/8636225" } ], "uniprot_canonical_ac": "P62826-1" }, { "start_pos": 182, "end_pos": 182, "sequence_org": "D", "sequence_mut": "A", "comment": "Abolishes interaction with Ran and impairs chromosome localization.", "evidence": [ { "database": "UniProtKB", "id": "P18754", "url": "https://www.uniprot.org/uniprotkb/P18754" }, { "database": "PubMed", "id": "17435751", "url": "https://pubmed.ncbi.nlm.nih.gov/17435751" }, { "database": "PubMed", "id": "12194828", "url": "https://pubmed.ncbi.nlm.nih.gov/12194828" } ], "uniprot_canonical_ac": "P18754-1" } ], "record_id": "pubmed.12194828", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Hydrogen peroxide triggers nuclear export of telomerase reverse transcriptase via Src kinase family-dependent phosphorylation of tyrosine 707.", "journal": "Mol. Cell. Biol.", "date": "2003", "authors": "Haendeler J, Hoffmann J, Brandes RP, Zeiher AM, Dimmeler S", "reference": { "type": "PubMed", "id": "12808100", "url": "https://pubmed.ncbi.nlm.nih.gov/12808100" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P62826-1", "protein_name": "GTP-binding nuclear protein Ran", "gene_name": "RAN", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14746-1", "protein_name": "Telomerase reverse transcriptase", "gene_name": "TERT", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14980-1", "protein_name": "Exportin-1", "gene_name": "XPO1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P62826", "url": "https://www.uniprot.org/uniprotkb/P62826" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 707, "end_pos": 707, "sequence_org": "Y", "sequence_mut": "F", "comment": "Abolishes oxidative stress-induced phosphorylation and RAN binding. 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Cell. Biol.", "date": "2003", "authors": "Hakata Y, Yamada M, Shida H", "reference": { "type": "PubMed", "id": "14612415", "url": "https://pubmed.ncbi.nlm.nih.gov/14612415" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P62826-1", "protein_name": "GTP-binding nuclear protein Ran", "gene_name": "RAN", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14980-1", "protein_name": "Exportin-1", "gene_name": "XPO1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P62826", "url": "https://www.uniprot.org/uniprotkb/P62826" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 191, "end_pos": 191, "sequence_org": "S", "sequence_mut": "A", "comment": "Does not abolish Rex-mediated mRNA export.", "evidence": [ { "database": "UniProtKB", "id": "O14980", "url": "https://www.uniprot.org/uniprotkb/O14980" }, { "database": "PubMed", "id": "14612415", "url": "https://pubmed.ncbi.nlm.nih.gov/14612415" } ], "uniprot_canonical_ac": "O14980-1" }, { "start_pos": 284, "end_pos": 284, "sequence_org": "V", "sequence_mut": "E", "comment": "Does not abolish Rex-mediated mRNA export.", "evidence": [ { "database": "UniProtKB", "id": "O14980", "url": "https://www.uniprot.org/uniprotkb/O14980" }, { "database": "PubMed", "id": "14612415", "url": "https://pubmed.ncbi.nlm.nih.gov/14612415" } ], "uniprot_canonical_ac": "O14980-1" }, { "start_pos": 334, "end_pos": 334, "sequence_org": "D", "sequence_mut": "G", "comment": "Does not abolish Rex-mediated mRNA export.", "evidence": [ { "database": "UniProtKB", "id": "O14980", "url": "https://www.uniprot.org/uniprotkb/O14980" }, { "database": "PubMed", "id": "14612415", "url": "https://pubmed.ncbi.nlm.nih.gov/14612415" } ], "uniprot_canonical_ac": "O14980-1" }, { "start_pos": 337, "end_pos": 337, "sequence_org": "I", "sequence_mut": "L", "comment": "Does not abolish Rex-mediated mRNA export.", "evidence": [ { "database": "UniProtKB", "id": "O14980", "url": "https://www.uniprot.org/uniprotkb/O14980" }, { "database": "PubMed", "id": "14612415", "url": "https://pubmed.ncbi.nlm.nih.gov/14612415" } ], "uniprot_canonical_ac": "O14980-1" }, { "start_pos": 346, "end_pos": 346, "sequence_org": "T", "sequence_mut": "A", "comment": "Does not abolish Rex-mediated mRNA export.", "evidence": [ { "database": "UniProtKB", "id": "O14980", "url": "https://www.uniprot.org/uniprotkb/O14980" }, { "database": "PubMed", "id": "14612415", "url": "https://pubmed.ncbi.nlm.nih.gov/14612415" } ], "uniprot_canonical_ac": "O14980-1" }, { "start_pos": 402, "end_pos": 402, "sequence_org": "V", "sequence_mut": "I", "comment": "Does not abolish Rex-mediated mRNA export.", "evidence": [ { "database": "UniProtKB", "id": "O14980", "url": "https://www.uniprot.org/uniprotkb/O14980" }, { "database": "PubMed", "id": "14612415", "url": "https://pubmed.ncbi.nlm.nih.gov/14612415" } ], "uniprot_canonical_ac": "O14980-1" }, { "start_pos": 411, "end_pos": 411, "sequence_org": "P", "sequence_mut": "T", "comment": "Strongly abolishes interaction with Rex and RANBP3, abolishes Rex-mediated mRNA export. Does not abolish interaction with RANBP3; when associated with S-414. Abolishes Rex multimerization; when associated with S-414.", "evidence": [ { "database": "UniProtKB", "id": "O14980", "url": "https://www.uniprot.org/uniprotkb/O14980" }, { "database": "PubMed", "id": "14612415", "url": "https://pubmed.ncbi.nlm.nih.gov/14612415" } ], "uniprot_canonical_ac": "O14980-1" }, { "start_pos": 412, "end_pos": 412, "sequence_org": "M", "sequence_mut": "V", "comment": "Does not abolish interaction with Rex and RANBP3, and Rex-mediated mRNA export.", "evidence": [ { "database": "UniProtKB", "id": "O14980", "url": "https://www.uniprot.org/uniprotkb/O14980" }, { "database": "PubMed", "id": "14612415", "url": "https://pubmed.ncbi.nlm.nih.gov/14612415" } ], "uniprot_canonical_ac": "O14980-1" }, { "start_pos": 414, "end_pos": 414, "sequence_org": "F", "sequence_mut": "S", "comment": "Strongly abolishes interaction with Rex and RANBP3, abolishes Rex-mediated mRNA export. Does not abolish interaction with RANBP3; when associated with T-411. 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Cell", "date": "2004", "authors": "Petosa C, Schoehn G, Askjaer P, Bauer U, Moulin M, Steuerwald U, Soler-Lopez M, Baudin F, Mattaj IW, Muller CW", "reference": { "type": "PubMed", "id": "15574331", "url": "https://pubmed.ncbi.nlm.nih.gov/15574331" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P62826-1", "protein_name": "GTP-binding nuclear protein Ran", "gene_name": "RAN", "tax_name": "Human" }, { "uniprot_canonical_ac": "A8CG34-1", "protein_name": "Nuclear envelope pore membrane protein POM 121C", "gene_name": "POM121C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35658-1", "protein_name": "Nuclear pore complex protein Nup214", "gene_name": "NUP214", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92621-1", "protein_name": "Nuclear pore complex protein Nup205", "gene_name": "NUP205", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5SRE5-1", "protein_name": "Nucleoporin NUP188", "gene_name": "NUP188", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BW27-1", "protein_name": "Nuclear pore complex protein Nup85", "gene_name": "NUP85", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15504-1", "protein_name": "Nucleoporin NUP42", "gene_name": "NUP42", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKX7-1", "protein_name": "Nuclear pore complex protein Nup50", "gene_name": "NUP50", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57740-1", "protein_name": "Nuclear pore complex protein Nup107", "gene_name": "NUP107", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUM0-1", "protein_name": "Nuclear pore complex protein Nup133", "gene_name": "NUP133", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BTX1-1", "protein_name": "Nucleoporin NDC1", "gene_name": "NDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH3-1", "protein_name": "Nucleoporin Nup43", "gene_name": "NUP43", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TEM1-1", "protein_name": "Nuclear pore membrane glycoprotein 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"P49792-1", "protein_name": "E3 SUMO-protein ligase RanBP2", "gene_name": "RANBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99567-1", "protein_name": "Nuclear pore complex protein Nup88", "gene_name": "NUP88", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78406-1", "protein_name": "mRNA export factor RAE1", "gene_name": "RAE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH4-1", "protein_name": "Nucleoporin Nup37", "gene_name": "NUP37", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N1F7-1", "protein_name": "Nuclear pore complex protein Nup93", "gene_name": "NUP93", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z3B4-1", "protein_name": "Nucleoporin p54", "gene_name": "NUP54", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12270-1", "protein_name": "Nucleoprotein TPR", "gene_name": "TPR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NRG9-1", "protein_name": "Aladin", "gene_name": "AAAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37198-1", "protein_name": "Nuclear pore glycoprotein p62", "gene_name": "NUP62", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P62826", "url": "https://www.uniprot.org/uniprotkb/P62826" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 428, "end_pos": 447, "sequence_org": "EEVLVVENDQGEVVREFMKD", "sequence_mut": "QQVLVVQNNQGQVVRQFMKN", "comment": "Abolishes Ran binding activity in absence of cargo and abolishes partially Ran binding activity in presence of cargo.", "evidence": [ { "database": "UniProtKB", "id": "O14980", "url": "https://www.uniprot.org/uniprotkb/O14980" }, { "database": "PubMed", "id": "15574331", "url": "https://pubmed.ncbi.nlm.nih.gov/15574331" } ], "uniprot_canonical_ac": "O14980-1" }, { "start_pos": 430, "end_pos": 433, "sequence_org": "VLVV", "sequence_mut": "DEDE", "comment": "Abolishes Ran binding 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}, { "database": "PubMed", "id": "15574331", "url": "https://pubmed.ncbi.nlm.nih.gov/15574331" } ], "uniprot_canonical_ac": "O14980-1" }, { "start_pos": 513, "end_pos": 513, "sequence_org": "E", "sequence_mut": "A", "comment": "Abolishes Ran binding activity and nuclear export complex formation. Abolishes Ran binding activity and nuclear export complex formation; when associated with A-553 and A-554.", "evidence": [ { "database": "UniProtKB", "id": "O14980", "url": "https://www.uniprot.org/uniprotkb/O14980" }, { "database": "PubMed", "id": "15574331", "url": "https://pubmed.ncbi.nlm.nih.gov/15574331" } ], "uniprot_canonical_ac": "O14980-1" }, { "start_pos": 525, "end_pos": 525, "sequence_org": "L", "sequence_mut": "A", "comment": "Enhances Ran binding activity and does not abolish nuclear export complex formation. Does not abolish Ran binding activity and partially abolish nuclear export complex formation; when associated with A-561. Does not abolish Ran binding activity and partially abolish nuclear export complex formation; when associated with A-568 and A-572.", "evidence": [ { "database": "UniProtKB", "id": "O14980", "url": "https://www.uniprot.org/uniprotkb/O14980" }, { "database": "PubMed", "id": "15574331", "url": "https://pubmed.ncbi.nlm.nih.gov/15574331" } ], "uniprot_canonical_ac": "O14980-1" }, { "start_pos": 550, "end_pos": 550, "sequence_org": "Q", "sequence_mut": "A", "comment": "Enhances Ran binding activity and does not abolish nuclear export complex formation; when associated with A-553 and A-590.", "evidence": [ { "database": "UniProtKB", "id": "O14980", "url": "https://www.uniprot.org/uniprotkb/O14980" }, { "database": "PubMed", "id": "15574331", "url": "https://pubmed.ncbi.nlm.nih.gov/15574331" } ], "uniprot_canonical_ac": "O14980-1" }, { "start_pos": 553, "end_pos": 553, "sequence_org": "R", "sequence_mut": "A", "comment": "Enhances Ran binding activity and does not abolish nuclear export complex formation; when associated with A-550 and A-590. Abolishes Ran binding activity and nuclear export complex formation; when associated with A-513 and A-554.", "evidence": [ { "database": "UniProtKB", "id": "O14980", "url": "https://www.uniprot.org/uniprotkb/O14980" }, { "database": "PubMed", "id": "15574331", "url": "https://pubmed.ncbi.nlm.nih.gov/15574331" } ], "uniprot_canonical_ac": "O14980-1" }, { "start_pos": 554, "end_pos": 554, "sequence_org": "F", "sequence_mut": "A", "comment": "Partially abolishes Ran binding activity and does not abolish nuclear export complex formation. Abolishes Ran binding activity and nuclear export complex formation; when associated with A-561. Abolishes Ran binding activity and nuclear export complex formation; when associated with A-553 and A-513.", "evidence": [ { "database": "UniProtKB", "id": "O14980", "url": "https://www.uniprot.org/uniprotkb/O14980" }, { "database": "PubMed", "id": "15574331", "url": "https://pubmed.ncbi.nlm.nih.gov/15574331" } ], "uniprot_canonical_ac": "O14980-1" }, { "start_pos": 561, "end_pos": 561, "sequence_org": "F", "sequence_mut": "A", "comment": "Abolishes Ran binding activity and nuclear export complex formation. Abolishes Ran binding activity and nuclear export complex formation; when associated with A-554. Does not abolish Ran binding activity and partially abolish nuclear export complex formation; when associated with A-525.", "evidence": [ { "database": "UniProtKB", "id": "O14980", "url": "https://www.uniprot.org/uniprotkb/O14980" }, { "database": "PubMed", "id": "15574331", "url": "https://pubmed.ncbi.nlm.nih.gov/15574331" } ], "uniprot_canonical_ac": "O14980-1" }, { "start_pos": 568, "end_pos": 568, "sequence_org": "K", "sequence_mut": "A", "comment": "Does not abolish Ran binding activity and partially abolish nuclear export complex formation; when associated with A-525 and A-572.", "evidence": [ { "database": "UniProtKB", "id": "O14980", "url": "https://www.uniprot.org/uniprotkb/O14980" }, { "database": "PubMed", "id": "15574331", "url": "https://pubmed.ncbi.nlm.nih.gov/15574331" } ], "uniprot_canonical_ac": "O14980-1" }, { "start_pos": 572, "end_pos": 572, "sequence_org": "F", "sequence_mut": "A", "comment": "Does not abolish Ran binding activity and partially abolish nuclear export complex formation; when associated with A-525 and A-568.", "evidence": [ { "database": "UniProtKB", "id": "O14980", "url": "https://www.uniprot.org/uniprotkb/O14980" }, { "database": "PubMed", "id": "15574331", "url": "https://pubmed.ncbi.nlm.nih.gov/15574331" } ], "uniprot_canonical_ac": "O14980-1" }, { "start_pos": 583, "end_pos": 583, "sequence_org": "M", "sequence_mut": "A", "comment": "Enhances Ran binding activity; when associated with A-590.", "evidence": [ { "database": "UniProtKB", "id": "O14980", "url": "https://www.uniprot.org/uniprotkb/O14980" }, { "database": "PubMed", "id": "15574331", "url": "https://pubmed.ncbi.nlm.nih.gov/15574331" } ], "uniprot_canonical_ac": "O14980-1" }, { "start_pos": 590, "end_pos": 590, "sequence_org": "K", "sequence_mut": "A", "comment": "Enhances Ran binding activity and does not abolish nuclear export complex formation. Enhances Ran binding activity and does not abolish nuclear export complex formation; when associated with A-583. Enhances Ran binding activity and does not abolish nuclear export complex formation; when associated with A-550 and A-553.", "evidence": [ { "database": "UniProtKB", "id": "O14980", "url": "https://www.uniprot.org/uniprotkb/O14980" }, { "database": "PubMed", "id": "15574331", "url": "https://pubmed.ncbi.nlm.nih.gov/15574331" } ], "uniprot_canonical_ac": "O14980-1" } ], "record_id": "pubmed.15574331", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 29 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Phosphorylation of RanGAP1 stabilizes its interaction with Ran and RanBP1.", "journal": "Cell Struct. Funct.", "date": "2005", "authors": "Takeda E, Hieda M, Katahira J, Yoneda Y", "reference": { "type": "PubMed", "id": "16428860", "url": "https://pubmed.ncbi.nlm.nih.gov/16428860" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P62826-1", "protein_name": "GTP-binding nuclear protein Ran", "gene_name": "RAN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P43487-1", "protein_name": "Ran-specific GTPase-activating protein", "gene_name": "RANBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46060-1", "protein_name": "Ran GTPase-activating protein 1", "gene_name": "RANGAP1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P62826", "url": "https://www.uniprot.org/uniprotkb/P62826" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 356, "end_pos": 356, "sequence_org": "S", "sequence_mut": "A", "comment": "No effect on phosphorylation.", "evidence": [ { "database": "UniProtKB", "id": "P46060", "url": "https://www.uniprot.org/uniprotkb/P46060" }, { "database": "PubMed", "id": "16428860", "url": "https://pubmed.ncbi.nlm.nih.gov/16428860" } ], "uniprot_canonical_ac": "P46060-1" }, { "start_pos": 358, "end_pos": 358, "sequence_org": "S", "sequence_mut": "A", "comment": "Strongly decreased phosphorylation. No effect on sumoylation.", "evidence": [ { "database": "UniProtKB", "id": "P46060", "url": "https://www.uniprot.org/uniprotkb/P46060" }, { "database": "PubMed", "id": "16428860", "url": "https://pubmed.ncbi.nlm.nih.gov/16428860" } ], "uniprot_canonical_ac": "P46060-1" }, { "start_pos": 91, "end_pos": 91, "sequence_org": "R", "sequence_mut": "A", "comment": "Abolishes RANGTPase activation.", "evidence": [ { "database": "UniProtKB", "id": "P46060", "url": "https://www.uniprot.org/uniprotkb/P46060" }, { "database": "PubMed", "id": "16428860", "url": "https://pubmed.ncbi.nlm.nih.gov/16428860" } ], "uniprot_canonical_ac": "P46060-1" } ], "phosphorylation": [ { "start_pos": 358, "end_pos": 358, "kinase_uniprot_canonical_ac": "P68400-1", "kinase_gene_name": "CSNK2A1", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P46060", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P46060" }, { "database": "PubMed", "id": "16428860", "url": 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"field": "total", "count": 3 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Membrane accumulation of influenza A virus hemagglutinin triggers nuclear export of the viral genome via protein kinase Calpha-mediated activation of ERK signaling.", "journal": "The Journal of biological chemistry", "date": "2006", "authors": "Marjuki H, Alam MI, Ehrhardt C, Wagner R, 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"tax_name": "Human" }, { "uniprot_canonical_ac": "O15504-1", "protein_name": "Nucleoporin NUP42", "gene_name": "NUP42", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKX7-1", "protein_name": "Nuclear pore complex protein Nup50", "gene_name": "NUP50", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57740-1", "protein_name": "Nuclear pore complex protein Nup107", "gene_name": "NUP107", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUM0-1", "protein_name": "Nuclear pore complex protein Nup133", "gene_name": "NUP133", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BTX1-1", "protein_name": "Nucleoporin NDC1", "gene_name": "NDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH3-1", "protein_name": "Nucleoporin Nup43", "gene_name": "NUP43", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TEM1-1", "protein_name": "Nuclear pore membrane glycoprotein 210", "gene_name": "NUP210", "tax_name": "Human" }, { "uniprot_canonical_ac": "P55735-1", "protein_name": "Protein 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"uniprot_canonical_ac": "Q99567-1", "protein_name": "Nuclear pore complex protein Nup88", "gene_name": "NUP88", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78406-1", "protein_name": "mRNA export factor RAE1", "gene_name": "RAE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH4-1", "protein_name": "Nucleoporin Nup37", "gene_name": "NUP37", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N1F7-1", "protein_name": "Nuclear pore complex protein Nup93", "gene_name": "NUP93", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z3B4-1", "protein_name": "Nucleoporin p54", "gene_name": "NUP54", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12270-1", "protein_name": "Nucleoprotein TPR", "gene_name": "TPR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NRG9-1", "protein_name": "Aladin", "gene_name": "AAAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37198-1", "protein_name": "Nuclear pore glycoprotein p62", "gene_name": "NUP62", "tax_name": "Human" } ], 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"count": 0 } ], "sort_fields": [] } ] }, { "title": "Polo-like kinase 1-mediated phosphorylation of the GTP-binding protein Ran is important for bipolar spindle formation.", "journal": "Biochemical and biophysical research communications", "date": "2006", "authors": "Feng Y, Yuan JH, Maloid SC, Fisher R, Copeland TD, Longo DL, Conrads TP, Veenstra TD, Ferris A, Hughes S, Dimitrov DS, Ferris DK", "reference": { "type": "PubMed", "id": "16930555", "url": "https://pubmed.ncbi.nlm.nih.gov/16930555" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P62826-1", "protein_name": "GTP-binding nuclear protein Ran", "gene_name": "RAN", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P62826", "url": "https://www.uniprot.org/uniprotkb/P62826" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 135, "end_pos": 135, "kinase_uniprot_canonical_ac": "P53350-1", "kinase_gene_name": "PLK1", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P62826", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P62826" }, { "database": "PubMed", "id": "16930555", "url": "https://pubmed.ncbi.nlm.nih.gov/16930555" } ], "site_lbl": "Ser135", "uniprot_canonical_ac": "P62826-1" }, { "start_pos": 135, "end_pos": 135, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P62826", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P62826" }, { "database": "PubMed", "id": "20068231", "url": "https://pubmed.ncbi.nlm.nih.gov/20068231" }, { "database": "PubMed", "id": "16930555", "url": "https://pubmed.ncbi.nlm.nih.gov/16930555" }, { "database": "PubMed", "id": "29040603", "url": "https://pubmed.ncbi.nlm.nih.gov/29040603" } ], "site_lbl": "Ser135", "uniprot_canonical_ac": 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"sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Nuclear traffic of influenza virus proteins and ribonucleoprotein complexes.", "journal": "Virus research", "date": "2007", "authors": "Boulo S, Akarsu H, Ruigrok RW, Baudin F", "reference": { "type": "PubMed", "id": "17081640", "url": "https://pubmed.ncbi.nlm.nih.gov/17081640" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P62826-1", "protein_name": "GTP-binding nuclear protein Ran", "gene_name": "RAN", "tax_name": "Human" }, { "uniprot_canonical_ac": "A8CG34-1", "protein_name": "Nuclear envelope pore membrane protein POM 121C", "gene_name": "POM121C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35658-1", "protein_name": "Nuclear pore complex protein Nup214", "gene_name": "NUP214", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92621-1", "protein_name": "Nuclear pore complex protein Nup205", "gene_name": "NUP205", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5SRE5-1", "protein_name": "Nucleoporin NUP188", "gene_name": "NUP188", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BW27-1", "protein_name": "Nuclear pore complex protein Nup85", "gene_name": "NUP85", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15504-1", "protein_name": "Nucleoporin NUP42", "gene_name": "NUP42", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKX7-1", "protein_name": "Nuclear pore complex protein Nup50", "gene_name": "NUP50", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57740-1", "protein_name": "Nuclear pore complex protein Nup107", "gene_name": "NUP107", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUM0-1", "protein_name": "Nuclear pore complex protein Nup133", "gene_name": "NUP133", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BTX1-1", "protein_name": "Nucleoporin NDC1", "gene_name": "NDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH3-1", "protein_name": "Nucleoporin Nup43", "gene_name": "NUP43", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TEM1-1", "protein_name": "Nuclear pore membrane glycoprotein 210", "gene_name": "NUP210", "tax_name": "Human" }, { "uniprot_canonical_ac": "P55735-1", "protein_name": "Protein SEC13 homolog", "gene_name": "SEC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75694-1", "protein_name": "Nuclear pore complex protein Nup155", "gene_name": "NUP155", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH5-1", "protein_name": "Nucleoporin NUP35", "gene_name": "NUP35", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14980-1", "protein_name": "Exportin-1", "gene_name": "XPO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96HA1-1", "protein_name": "Nuclear envelope pore membrane protein POM 121", "gene_name": "POM121", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49790-1", "protein_name": "Nuclear pore complex protein Nup153", "gene_name": "NUP153", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12769-1", "protein_name": "Nuclear pore complex protein Nup160", "gene_name": "NUP160", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49792-1", "protein_name": "E3 SUMO-protein ligase RanBP2", "gene_name": "RANBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99567-1", "protein_name": "Nuclear pore complex protein Nup88", "gene_name": "NUP88", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78406-1", "protein_name": "mRNA export factor RAE1", "gene_name": "RAE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH4-1", "protein_name": "Nucleoporin Nup37", "gene_name": "NUP37", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N1F7-1", "protein_name": "Nuclear pore complex protein Nup93", "gene_name": "NUP93", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z3B4-1", "protein_name": "Nucleoporin p54", "gene_name": "NUP54", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12270-1", "protein_name": "Nucleoprotein TPR", "gene_name": "TPR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NRG9-1", "protein_name": "Aladin", "gene_name": "AAAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37198-1", "protein_name": "Nuclear pore glycoprotein p62", "gene_name": "NUP62", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P62826", "url": "https://www.uniprot.org/uniprotkb/P62826" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.17081640", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 29 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Human DNA replication-related element binding factor (hDREF) self-association via hATC domain is necessary for its nuclear accumulation and DNA binding.", "journal": "The Journal of biological chemistry", "date": "2007", "authors": "Yamashita D, Komori H, Higuchi Y, Yamaguchi T, Osumi T, Hirose F", "reference": { "type": "PubMed", "id": "17209048", "url": "https://pubmed.ncbi.nlm.nih.gov/17209048" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P62826-1", "protein_name": "GTP-binding nuclear protein Ran", "gene_name": "RAN", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96006-1", "protein_name": "E3 SUMO-protein ligase ZBED1", "gene_name": "ZBED1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75132-1", "protein_name": "Zinc finger BED domain-containing protein 4", "gene_name": "ZBED4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14974-1", "protein_name": "Importin subunit beta-1", "gene_name": "KPNB1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P62826", "url": "https://www.uniprot.org/uniprotkb/P62826" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 69, "end_pos": 69, "sequence_org": "Q", "sequence_mut": "L", "comment": "Strongly decreased GTPase activity. Probably locked in the GTP-bound form. Loss of interaction with NUTF2. Decreases nuclear location and leads to cytoplasmic location during interphase. Loss of function in importin-mediated protein nuclear import. High activity in triggering microtubule assembly at mitotic chromosomes. 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Abolishes interaction with SUMO1 and reduces SUMOylation of CHD3/Mi2-alpha.", "evidence": [ { "database": "UniProtKB", "id": "O96006", "url": "https://www.uniprot.org/uniprotkb/O96006" }, { "database": "PubMed", "id": "17209048", "url": "https://pubmed.ncbi.nlm.nih.gov/17209048" }, { "database": "PubMed", "id": "27068747", "url": "https://pubmed.ncbi.nlm.nih.gov/27068747" } ], "uniprot_canonical_ac": "O96006-1" }, { "start_pos": 599, "end_pos": 599, "sequence_org": "P", "sequence_mut": "A", "comment": "No effect on homodimerization or nuclear localization.", "evidence": [ { "database": "UniProtKB", "id": "O96006", "url": "https://www.uniprot.org/uniprotkb/O96006" }, { "database": "PubMed", "id": "17209048", "url": "https://pubmed.ncbi.nlm.nih.gov/17209048" } ], "uniprot_canonical_ac": "O96006-1" }, { "start_pos": 600, "end_pos": 601, "sequence_org": "LL", "sequence_mut": "AA", "comment": "Abolishes homodimerization and nuclear localization. Abolishes homodimerization, multimerization, nuclear localization, and DNA binding activity; when associated with A-604-A-A-605. Abolishes interaction with SUMO1 and reduces sumoylation of CHD3/Mi2-alpha; when associated with 604-A-A-605.", "evidence": [ { "database": "UniProtKB", "id": "O96006", "url": "https://www.uniprot.org/uniprotkb/O96006" }, { "database": "PubMed", "id": "17209048", "url": "https://pubmed.ncbi.nlm.nih.gov/17209048" }, { "database": "PubMed", "id": "27068747", "url": "https://pubmed.ncbi.nlm.nih.gov/27068747" } ], "uniprot_canonical_ac": "O96006-1" }, { "start_pos": 604, "end_pos": 605, "sequence_org": "VL", "sequence_mut": "AA", "comment": "Reduces homodimerization and nuclear localization. Abolishes homodimerization, multimerization, nuclear localization, and DNA binding activity; when associated with A-600-A-A-601. 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"evidence": [ { "database": "UniProtKB", "id": "O96006", "url": "https://www.uniprot.org/uniprotkb/O96006" }, { "database": "PubMed", "id": "17209048", "url": "https://pubmed.ncbi.nlm.nih.gov/17209048" } ], "uniprot_canonical_ac": "O96006-1" }, { "start_pos": 633, "end_pos": 633, "sequence_org": "R", "sequence_mut": "A", "comment": "No effect on homodimerization or nuclear localization.", "evidence": [ { "database": "UniProtKB", "id": "O96006", "url": "https://www.uniprot.org/uniprotkb/O96006" }, { "database": "PubMed", "id": "17209048", "url": "https://pubmed.ncbi.nlm.nih.gov/17209048" } ], "uniprot_canonical_ac": "O96006-1" } ], "record_id": "pubmed.17209048", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", 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"glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Premature initiation of mitosis in yeast lacking RCC1 or an interacting GTPase.", "journal": "Cell", "date": "1991", "authors": "Matsumoto T, Beach D", "reference": { "type": "PubMed", "id": "1855255", "url": "https://pubmed.ncbi.nlm.nih.gov/1855255" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P62826-1", "protein_name": "GTP-binding nuclear protein Ran", "gene_name": "RAN", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P62826", 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"o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "A survivin-ran complex regulates spindle formation in tumor cells.", "journal": "Molecular and cellular biology", "date": "2008", "authors": "Xia F, Canovas PM, Guadagno TM, Altieri DC", "reference": { "type": "PubMed", "id": "18591255", "url": "https://pubmed.ncbi.nlm.nih.gov/18591255" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P62826-1", "protein_name": "GTP-binding nuclear protein Ran", "gene_name": "RAN", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15392-1", "protein_name": "Baculoviral IAP repeat-containing protein 5", "gene_name": "BIRC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96GD4-1", "protein_name": "Aurora kinase B", "gene_name": "AURKB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q53HL2-1", "protein_name": "Borealin", "gene_name": "CDCA8", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P62826", "url": "https://www.uniprot.org/uniprotkb/P62826" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 24, "end_pos": 24, "sequence_org": "T", "sequence_mut": "L", "comment": "Has low binding affinity for GTP and GDP. Almost completely abolishes interaction with BIRC5.", "evidence": [ { "database": "UniProtKB", "id": "P62826", "url": "https://www.uniprot.org/uniprotkb/P62826" }, { "database": "PubMed", "id": "18591255", "url": "https://pubmed.ncbi.nlm.nih.gov/18591255" } ], "uniprot_canonical_ac": "P62826-1" }, { "start_pos": 69, "end_pos": 69, "sequence_org": "Q", "sequence_mut": "L", "comment": "Strongly decreased GTPase activity. Probably locked in the GTP-bound form. Loss of interaction with NUTF2. Decreases nuclear location and leads to cytoplasmic location during interphase. Loss of function in importin-mediated protein nuclear import. High activity in triggering microtubule assembly at mitotic chromosomes. Blocks DNA replication; when associated with V-19.", "evidence": [ { "database": "UniProtKB", "id": "P62826", "url": "https://www.uniprot.org/uniprotkb/P62826" }, { "database": "PubMed", "id": "8421051", "url": "https://pubmed.ncbi.nlm.nih.gov/8421051" }, { "database": "PubMed", "id": "9822603", "url": "https://pubmed.ncbi.nlm.nih.gov/9822603" }, { "database": "PubMed", "id": "17209048", "url": "https://pubmed.ncbi.nlm.nih.gov/17209048" }, { "database": "PubMed", "id": "10408446", "url": "https://pubmed.ncbi.nlm.nih.gov/10408446" }, { "database": "PubMed", "id": "9351834", "url": "https://pubmed.ncbi.nlm.nih.gov/9351834" }, { "database": "PubMed", "id": "7819259", "url": "https://pubmed.ncbi.nlm.nih.gov/7819259" }, { "database": "PubMed", "id": "12194828", "url": "https://pubmed.ncbi.nlm.nih.gov/12194828" }, { "database": "PubMed", "id": "18591255", "url": "https://pubmed.ncbi.nlm.nih.gov/18591255" }, { "database": "PubMed", "id": "8636225", "url": "https://pubmed.ncbi.nlm.nih.gov/8636225" } ], "uniprot_canonical_ac": "P62826-1" }, { "start_pos": 69, "end_pos": 69, "sequence_org": "Q", "sequence_mut": "N", "comment": "Unable to hydrolyze GTP. Increases binding to BIRC5 and promotes exaggerated spindle formation.", "evidence": [ { "database": "UniProtKB", "id": "P62826", "url": "https://www.uniprot.org/uniprotkb/P62826" }, { "database": "PubMed", "id": "24915079", "url": "https://pubmed.ncbi.nlm.nih.gov/24915079" }, { "database": "PubMed", "id": "18591255", "url": "https://pubmed.ncbi.nlm.nih.gov/18591255" }, { "database": "PubMed", "id": "23878195", "url": "https://pubmed.ncbi.nlm.nih.gov/23878195" } ], "uniprot_canonical_ac": "P62826-1" }, { "start_pos": 65, "end_pos": 65, "sequence_org": "E", "sequence_mut": "A", "comment": "Almost abolishes RAN-binding. Does not disrupt binding to AURKB or CDCA8. Disrupts mitotic spindle assembly. Does not disrupt nuclear export.", "evidence": [ { "database": "UniProtKB", "id": "O15392", "url": "https://www.uniprot.org/uniprotkb/O15392" }, { "database": "PubMed", "id": "18591255", "url": "https://pubmed.ncbi.nlm.nih.gov/18591255" } ], "uniprot_canonical_ac": "O15392-1" } ], "record_id": "pubmed.18591255", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", 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"count": 0 } ], "sort_fields": [] } ] }, { "title": "The crystal structure of the Ran-Nup153ZnF2 complex: a general Ran docking site at the nuclear pore complex.", "journal": "Structure", "date": "2008", "authors": "Schrader N, Koerner C, Koessmeier K, Bangert JA, Wittinghofer A, Stoll R, Vetter IR", "reference": { "type": "PubMed", "id": "18611384", "url": "https://pubmed.ncbi.nlm.nih.gov/18611384" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P62826-1", "protein_name": "GTP-binding nuclear protein Ran", "gene_name": "RAN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49791-1", "protein_name": "Nuclear pore complex protein Nup153", "gene_name": "Nup153", "tax_name": "Rat" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P62826", "url": "https://www.uniprot.org/uniprotkb/P62826" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 714, "end_pos": 714, "sequence_org": "F", "sequence_mut": "A", "comment": "Reduces affinity for RAN; when associated with A-718.", "evidence": [ { "database": "UniProtKB", "id": "P49791", "url": "https://www.uniprot.org/uniprotkb/P49791" }, { "database": "PubMed", "id": "18611384", "url": "https://pubmed.ncbi.nlm.nih.gov/18611384" } ], "uniprot_canonical_ac": "P49791-1" }, { "start_pos": 718, "end_pos": 718, "sequence_org": "F", "sequence_mut": "A", "comment": "Reduces affinity for RAN; when associated with A-714.", "evidence": [ { "database": "UniProtKB", "id": "P49791", "url": "https://www.uniprot.org/uniprotkb/P49791" }, { "database": "PubMed", "id": "18611384", "url": "https://pubmed.ncbi.nlm.nih.gov/18611384" } ], "uniprot_canonical_ac": "P49791-1" } ], "record_id": "pubmed.18611384", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { 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