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N-acetylgalactosaminyltransferase-2 deletion alleviates lipoprotein retention in early atherosclerosis and attenuates aortic smooth muscle cell migration.", "journal": "Biochemical and biophysical research communications", "date": "2019", "authors": "Adhikara IM, Yagi K, Mayasari DS, Ikeda K, Kitagawa H, Miyata O, Igarashi M, Hatakeyama K, Asada Y, Hirata KI, Emoto N", "reference": { "type": "PubMed", "id": "30579596", "url": "https://pubmed.ncbi.nlm.nih.gov/30579596" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q8N6G5-1", "protein_name": "Chondroitin sulfate N-acetylgalactosaminyltransferase 2", "gene_name": "CSGALNACT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8C1F4-1", "protein_name": "Chondroitin sulfate N-acetylgalactosaminyltransferase 2", "gene_name": "Csgalnact2", "tax_name": "Mouse" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q8N6G5", "url": 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and invasion by modulating MAPK/ERK pathway through DUSP1.", "journal": "Cellular oncology (Dordrecht, Netherlands)", "date": "2024-06", "authors": "Ma Mingjun, Wang Chao, Wu Meixuan, Gu Sijia, Yang Jiani, Zhang Yue, Cheng Shanshan, Xu Shilin, Zhang Minghai, Wu Yongsong, Zhao Yaqian, Tian Xiu, Voon Dominic Chih-Cheng, Takahashi Chiaki, Sheng Jindan, Wang Yu", "reference": { "type": "PubMed", "id": "38082211", "url": "https://pubmed.ncbi.nlm.nih.gov/38082211" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q8N6G5-1", "protein_name": "Chondroitin sulfate N-acetylgalactosaminyltransferase 2", "gene_name": "CSGALNACT2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q8N6G5", "url": "https://www.uniprot.org/uniprotkb/Q8N6G5" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.38082211", "abstract": "", 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No effect on stimulation of interferon production.", "evidence": [ { "database": "UniProtKB", "id": "Q8N884", "url": "https://www.uniprot.org/uniprotkb/Q8N884" }, { "database": "PubMed", "id": "24462292", "url": "https://pubmed.ncbi.nlm.nih.gov/24462292" }, { "database": "PubMed", "id": "23707061", "url": "https://pubmed.ncbi.nlm.nih.gov/23707061" } ], "uniprot_canonical_ac": "Q8N884-1" }, { "start_pos": 394, "end_pos": 394, "sequence_org": "K", "sequence_mut": "E", "comment": "Abolishes homodimerization and subsequent nucleotidyltransferase activity. Abolishes stimulation of interferon production. 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}, { "title": "MARCH8 attenuates cGAS-mediated innate immune responses through ubiquitylation.", "journal": "Science signaling", "date": "2022", "authors": "Yang X, Shi C, Li H, Shen S, Su C, Yin H", "reference": { "type": "PubMed", "id": "35503863", "url": "https://pubmed.ncbi.nlm.nih.gov/35503863" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q8N884-1", "protein_name": "Cyclic GMP-AMP synthase", "gene_name": "CGAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5T0T0-1", "protein_name": "E3 ubiquitin-protein ligase MARCHF8", "gene_name": "MARCHF8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9DBD2-1", "protein_name": "E3 ubiquitin-protein ligase MARCHF8", "gene_name": "Marchf8", "tax_name": "Mouse" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q8N884", "url": "https://www.uniprot.org/uniprotkb/Q8N884" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": 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"journal": "Clinical genetics", "date": "2009", "authors": "Jongmans MC, van Ravenswaaij-Arts CM, Pitteloud N, Ogata T, Sato N, Claahsen-van der Grinten HL, van der Donk K, Seminara S, Bergman JE, Brunner HG, Crowley WF Jr, Hoefsloot LH", "reference": { "type": "PubMed", "id": "19021638", "url": "https://pubmed.ncbi.nlm.nih.gov/19021638" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9P2D1-1", "protein_name": "ATP-dependent chromatin remodeler CHD7", "gene_name": "CHD7", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9P2D1", "url": "https://www.uniprot.org/uniprotkb/Q9P2D1" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.19021638", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", 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