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5-lipoxygenase-activating protein", "gene_name": "ALOX5AP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q08477-1", "protein_name": "Cytochrome P450 4F3", "gene_name": "CYP4F3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HBI6-1", "protein_name": "Cytochrome P450 4F11", "gene_name": "CYP4F11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19440-1", "protein_name": "Glutathione hydrolase 1 proenzyme", "gene_name": "GGT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P36269-1", "protein_name": "Glutathione hydrolase 5 proenzyme", "gene_name": "GGT5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09917-1", "protein_name": "Polyunsaturated fatty acid 5-lipoxygenase", "gene_name": "ALOX5", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P16444", "url": "https://www.uniprot.org/uniprotkb/P16444" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.6122208", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 21 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Conversion of leukotriene D4 to leukotriene E4 by a dipeptidase released from the specific granule of human polymorphonuclear leucocytes.", "journal": "Immunology", "date": "1983", "authors": "Lee CW, Lewis RA, Corey EJ, Austen KF", "reference": { "type": "PubMed", "id": "6293969", "url": "https://pubmed.ncbi.nlm.nih.gov/6293969" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P16444-1", "protein_name": "Dipeptidase 1", "gene_name": "DPEP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98187-1", "protein_name": "Cytochrome P450 4F8", "gene_name": "CYP4F8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49137-1", "protein_name": "MAP kinase-activated protein kinase 2", "gene_name": "MAPKAPK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16873-1", "protein_name": "Leukotriene C4 synthase", "gene_name": "LTC4S", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14914-1", "protein_name": "Prostaglandin reductase 1", "gene_name": "PTGR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H4A9-1", "protein_name": "Dipeptidase 2", "gene_name": "DPEP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78329-1", "protein_name": "Cytochrome P450 4F2", "gene_name": "CYP4F2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q02928-1", "protein_name": "Cytochrome P450 4A11", "gene_name": "CYP4A11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P13584-1", "protein_name": "Cytochrome P450 4B1", "gene_name": "CYP4B1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5TCH4-1", "protein_name": "Cytochrome P450 4A22", "gene_name": "CYP4A22", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6NT55-1", "protein_name": "Ultra-long-chain fatty acid omega-hydroxylase", "gene_name": "CYP4F22", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16050-1", "protein_name": "Polyunsaturated fatty acid lipoxygenase ALOX15", "gene_name": "ALOX15", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33527-1", "protein_name": "Multidrug resistance-associated protein 1", "gene_name": "ABCC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09960-1", "protein_name": "Leukotriene A-4 hydrolase", "gene_name": "LTA4H", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20292-1", "protein_name": "Arachidonate 5-lipoxygenase-activating protein", "gene_name": "ALOX5AP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q08477-1", "protein_name": "Cytochrome P450 4F3", "gene_name": "CYP4F3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HBI6-1", "protein_name": "Cytochrome P450 4F11", "gene_name": "CYP4F11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19440-1", "protein_name": "Glutathione hydrolase 1 proenzyme", "gene_name": "GGT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P36269-1", "protein_name": "Glutathione hydrolase 5 proenzyme", "gene_name": "GGT5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09917-1", "protein_name": "Polyunsaturated fatty acid 5-lipoxygenase", "gene_name": "ALOX5", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P16444", "url": "https://www.uniprot.org/uniprotkb/P16444" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.6293969", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 20 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": 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biological chemistry", "date": "1984-12-10", "authors": "Campbell B J, Forrester L J, Zahler W L, Burks M", "reference": { "type": "PubMed", "id": "6334084", "url": "https://pubmed.ncbi.nlm.nih.gov/6334084" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P16444-1", "protein_name": "Dipeptidase 1", "gene_name": "DPEP1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P16444", "url": "https://www.uniprot.org/uniprotkb/P16444" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.6334084", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Leukotriene A4 hydrolase in human leukocytes. Purification and properties.", "journal": "The Journal of biological chemistry", "date": "1984", "authors": "Radmark O, Shimizu T, Jornvall H, Samuelsson B", "reference": { "type": "PubMed", "id": "6490615", "url": "https://pubmed.ncbi.nlm.nih.gov/6490615" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P16444-1", "protein_name": "Dipeptidase 1", "gene_name": "DPEP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98187-1", "protein_name": "Cytochrome P450 4F8", "gene_name": "CYP4F8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49137-1", "protein_name": "MAP kinase-activated protein kinase 2", "gene_name": "MAPKAPK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16873-1", "protein_name": "Leukotriene C4 synthase", "gene_name": "LTC4S", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14914-1", "protein_name": "Prostaglandin reductase 1", "gene_name": "PTGR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H4A9-1", "protein_name": "Dipeptidase 2", "gene_name": "DPEP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78329-1", "protein_name": "Cytochrome P450 4F2", "gene_name": "CYP4F2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q02928-1", "protein_name": "Cytochrome P450 4A11", "gene_name": "CYP4A11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P13584-1", "protein_name": "Cytochrome P450 4B1", "gene_name": "CYP4B1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5TCH4-1", "protein_name": "Cytochrome P450 4A22", "gene_name": "CYP4A22", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6NT55-1", "protein_name": "Ultra-long-chain fatty acid omega-hydroxylase", "gene_name": "CYP4F22", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16050-1", "protein_name": "Polyunsaturated fatty acid lipoxygenase ALOX15", "gene_name": "ALOX15", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33527-1", "protein_name": "Multidrug resistance-associated protein 1", "gene_name": "ABCC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09960-1", "protein_name": "Leukotriene A-4 hydrolase", "gene_name": "LTA4H", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20292-1", "protein_name": "Arachidonate 5-lipoxygenase-activating protein", "gene_name": "ALOX5AP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q08477-1", "protein_name": "Cytochrome P450 4F3", "gene_name": "CYP4F3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HBI6-1", "protein_name": "Cytochrome P450 4F11", "gene_name": "CYP4F11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19440-1", "protein_name": "Glutathione hydrolase 1 proenzyme", "gene_name": "GGT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P36269-1", "protein_name": "Glutathione hydrolase 5 proenzyme", "gene_name": "GGT5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09917-1", "protein_name": "Polyunsaturated fatty acid 5-lipoxygenase", "gene_name": "ALOX5", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P16444", "url": "https://www.uniprot.org/uniprotkb/P16444" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.6490615", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 20 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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"Gene structural analysis and expression of human renal dipeptidase.", "journal": "Biotechnol. Prog.", "date": "1994", "authors": "Satoh S, Ohtsuka K, Keida Y, Kusunoki C, Konta Y, Niwa M, Kohsaka M", "reference": { "type": "PubMed", "id": "7764673", "url": "https://pubmed.ncbi.nlm.nih.gov/7764673" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P16444-1", "protein_name": "Dipeptidase 1", "gene_name": "DPEP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03154-1", "protein_name": "Aminoacylase-1", "gene_name": "ACY1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43488-1", "protein_name": "Aflatoxin B1 aldehyde reductase member 2", "gene_name": "AKR7A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NHP1-1", "protein_name": "Aflatoxin B1 aldehyde reductase member 4", "gene_name": "AKR7L", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95154-1", "protein_name": "Aldo-keto reductase family 7 member A3", "gene_name": "AKR7A3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08684-1", "protein_name": "Cytochrome P450 3A4", 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YF, Shimada T, Yamazaki H, Guengerich FP", "reference": { "type": "PubMed", "id": "7766804", "url": "https://pubmed.ncbi.nlm.nih.gov/7766804" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P16444-1", "protein_name": "Dipeptidase 1", "gene_name": "DPEP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03154-1", "protein_name": "Aminoacylase-1", "gene_name": "ACY1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43488-1", "protein_name": "Aflatoxin B1 aldehyde reductase member 2", "gene_name": "AKR7A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NHP1-1", "protein_name": "Aflatoxin B1 aldehyde reductase member 4", "gene_name": "AKR7L", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95154-1", "protein_name": "Aldo-keto reductase family 7 member A3", "gene_name": "AKR7A3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08684-1", "protein_name": "Cytochrome P450 3A4", "gene_name": "CYP3A4", "tax_name": "Human" }, { 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leukotriene C4 synthase, an integral membrane protein conjugating reduced glutathione to leukotriene A4.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "1994", "authors": "Lam BK, Penrose JF, Freeman GJ, Austen KF", "reference": { "type": "PubMed", "id": "8052639", "url": "https://pubmed.ncbi.nlm.nih.gov/8052639" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P16444-1", "protein_name": "Dipeptidase 1", "gene_name": "DPEP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98187-1", "protein_name": "Cytochrome P450 4F8", "gene_name": "CYP4F8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49137-1", "protein_name": "MAP kinase-activated protein kinase 2", "gene_name": "MAPKAPK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16873-1", "protein_name": "Leukotriene C4 synthase", "gene_name": "LTC4S", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14914-1", "protein_name": 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"Polyunsaturated fatty acid 5-lipoxygenase", "gene_name": "ALOX5", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P16444", "url": "https://www.uniprot.org/uniprotkb/P16444" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.8052639", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 20 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 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"count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Importance of Glu-125 in the catalytic activity of human renal dipeptidase.", "journal": "Biochimica et biophysica acta", "date": "1993", "authors": "Adachi H, Katayama T, Nakazato H, Tsujimoto M", "reference": { "type": "PubMed", "id": "8097406", "url": "https://pubmed.ncbi.nlm.nih.gov/8097406" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P16444-1", "protein_name": "Dipeptidase 1", "gene_name": "DPEP1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P16444", "url": "https://www.uniprot.org/uniprotkb/P16444" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 141, "end_pos": 141, "sequence_org": "E", "sequence_mut": "C", "comment": "Complete loss of 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Does not affect ability to bind neutrophils.", "evidence": [ { "database": "UniProtKB", "id": "P16444", "url": "https://www.uniprot.org/uniprotkb/P16444" }, { "database": "PubMed", "id": "31442408", "url": "https://pubmed.ncbi.nlm.nih.gov/31442408" }, { "database": "PubMed", "id": "8097406", "url": "https://pubmed.ncbi.nlm.nih.gov/8097406" } ], "uniprot_canonical_ac": "P16444-1" }, { "start_pos": 141, "end_pos": 141, "sequence_org": "E", "sequence_mut": "Q", "comment": "Partial loss of activity.", "evidence": [ { "database": "UniProtKB", "id": "P16444", "url": "https://www.uniprot.org/uniprotkb/P16444" }, { "database": "PubMed", "id": "8097406", "url": "https://pubmed.ncbi.nlm.nih.gov/8097406" } ], "uniprot_canonical_ac": "P16444-1" } ], "record_id": "pubmed.8097406", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Enzymatic inactivation of leukotriene B4 by a novel enzyme found in the porcine kidney. Purification and properties of leukotriene B4 12-hydroxydehydrogenase.", "journal": "The Journal of biological chemistry", "date": "1993", "authors": "Yokomizo T, Izumi T, Takahashi T, Kasama T, Kobayashi Y, Sato F, Taketani Y, Shimizu T", "reference": { "type": "PubMed", "id": "8394361", "url": "https://pubmed.ncbi.nlm.nih.gov/8394361" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P16444-1", "protein_name": "Dipeptidase 1", "gene_name": "DPEP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98187-1", "protein_name": "Cytochrome P450 4F8", "gene_name": "CYP4F8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49137-1", "protein_name": "MAP kinase-activated protein kinase 2", "gene_name": "MAPKAPK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16873-1", "protein_name": "Leukotriene C4 synthase", "gene_name": "LTC4S", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14914-1", "protein_name": "Prostaglandin reductase 1", "gene_name": 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"tax_name": "Human" }, { "uniprot_canonical_ac": "P09917-1", "protein_name": "Polyunsaturated fatty acid 5-lipoxygenase", "gene_name": "ALOX5", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P16444", "url": "https://www.uniprot.org/uniprotkb/P16444" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.8394361", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 21 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { 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Biophys. Acta", "date": "1993", "authors": "Satoh S, Kusunoki C, Konta Y, Niwa M, Kohsaka M", "reference": { "type": "PubMed", "id": "8439558", "url": "https://pubmed.ncbi.nlm.nih.gov/8439558" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P16444-1", "protein_name": "Dipeptidase 1", "gene_name": "DPEP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03154-1", "protein_name": "Aminoacylase-1", "gene_name": "ACY1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43488-1", "protein_name": "Aflatoxin B1 aldehyde reductase member 2", "gene_name": "AKR7A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NHP1-1", "protein_name": "Aflatoxin B1 aldehyde reductase member 4", "gene_name": "AKR7L", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95154-1", "protein_name": "Aldo-keto reductase family 7 member A3", "gene_name": "AKR7A3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08684-1", "protein_name": "Cytochrome P450 3A4", "gene_name": "CYP3A4", 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"authors": "Yokomizo T, Ogawa Y, Uozumi N, Kume K, Izumi T, Shimizu T", "reference": { "type": "PubMed", "id": "8576264", "url": "https://pubmed.ncbi.nlm.nih.gov/8576264" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P16444-1", "protein_name": "Dipeptidase 1", "gene_name": "DPEP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98187-1", "protein_name": "Cytochrome P450 4F8", "gene_name": "CYP4F8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49137-1", "protein_name": "MAP kinase-activated protein kinase 2", "gene_name": "MAPKAPK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16873-1", "protein_name": "Leukotriene C4 synthase", "gene_name": "LTC4S", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14914-1", "protein_name": "Prostaglandin reductase 1", "gene_name": "PTGR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H4A9-1", "protein_name": "Dipeptidase 2", "gene_name": "DPEP2", "tax_name": "Human" }, { 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3A4.", "journal": "Toxicology and applied pharmacology", "date": "1996", "authors": "Gallagher EP, Kunze KL, Stapleton PL, Eaton DL", "reference": { "type": "PubMed", "id": "8975785", "url": "https://pubmed.ncbi.nlm.nih.gov/8975785" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P16444-1", "protein_name": "Dipeptidase 1", "gene_name": "DPEP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03154-1", "protein_name": "Aminoacylase-1", "gene_name": "ACY1", "tax_name": "Human" }, { "uniprot_canonical_ac": "A9YTQ3-1", "protein_name": "Aryl hydrocarbon receptor repressor", "gene_name": "AHRR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35869-1", "protein_name": "Aryl hydrocarbon receptor", "gene_name": "AHR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27540-1", "protein_name": "Aryl hydrocarbon receptor nuclear translocator", "gene_name": "ARNT", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HBZ2-1", "protein_name": "Aryl 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"gene_name": "CYP4B1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5TCH4-1", "protein_name": "Cytochrome P450 4A22", "gene_name": "CYP4A22", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6NT55-1", "protein_name": "Ultra-long-chain fatty acid omega-hydroxylase", "gene_name": "CYP4F22", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16050-1", "protein_name": "Polyunsaturated fatty acid lipoxygenase ALOX15", "gene_name": "ALOX15", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33527-1", "protein_name": "Multidrug resistance-associated protein 1", "gene_name": "ABCC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09960-1", "protein_name": "Leukotriene A-4 hydrolase", "gene_name": "LTA4H", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20292-1", "protein_name": "Arachidonate 5-lipoxygenase-activating protein", "gene_name": "ALOX5AP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q08477-1", "protein_name": "Cytochrome P450 4F3", "gene_name": "CYP4F3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HBI6-1", "protein_name": "Cytochrome P450 4F11", "gene_name": "CYP4F11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19440-1", "protein_name": "Glutathione hydrolase 1 proenzyme", "gene_name": "GGT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P36269-1", "protein_name": "Glutathione hydrolase 5 proenzyme", "gene_name": "GGT5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09917-1", "protein_name": "Polyunsaturated fatty acid 5-lipoxygenase", "gene_name": "ALOX5", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P16444", "url": "https://www.uniprot.org/uniprotkb/P16444" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.9461497", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Molecular cloning, expression and catalytic activity of a human AKR7 member of the aldo-keto reductase superfamily: evidence that the major 2-carboxybenzaldehyde reductase from human liver is a homologue of rat aflatoxin B1-aldehyde reductase.", "journal": "The Biochemical journal", "date": "1998", "authors": "Ireland LS, Harrison DJ, Neal GE, Hayes JD", "reference": { "type": 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"protein_name": "Mitogen-activated protein kinase kinase kinase 1", "gene_name": "MAP3K1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43187-1", "protein_name": "Interleukin-1 receptor-associated kinase-like 2", "gene_name": "IRAK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P58753-1", "protein_name": "Toll/interleukin-1 receptor domain-containing adapter protein", "gene_name": "TIRAP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y4K3-1", "protein_name": "TNF receptor-associated factor 6", "gene_name": "TRAF6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09429-1", "protein_name": "High mobility group protein B1", "gene_name": "HMGB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15524-1", "protein_name": "Suppressor of cytokine signaling 1", "gene_name": "SOCS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02679-1", "protein_name": "Fibrinogen gamma chain", "gene_name": "FGG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9U6M0-1", "protein_name": "Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial", "gene_name": "ECSIT", "tax_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9NWZ3-1", "protein_name": "Interleukin-1 receptor-associated kinase 4", "gene_name": "IRAK4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6IA17-1", "protein_name": "Single Ig IL-1-related receptor", "gene_name": "SIGIRR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BQ95-1", "protein_name": "Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial", "gene_name": "ECSIT", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16671-1", "protein_name": "Platelet glycoprotein 4", "gene_name": "CD36", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60603-1", "protein_name": "Toll-like receptor 2", "gene_name": "TLR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00206-1", "protein_name": "Toll-like receptor 4", "gene_name": "TLR4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6Y9-1", "protein_name": "Lymphocyte antigen 96", "gene_name": "LY96", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06187-1", "protein_name": "Tyrosine-protein kinase BTK", "gene_name": "BTK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9QZH6-1", "protein_name": "Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial", "gene_name": "Ecsit", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "P02675-1", "protein_name": "Fibrinogen beta chain", "gene_name": "FGB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05109-1", "protein_name": "Protein S100-A8", "gene_name": "S100A8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51617-1", "protein_name": "Interleukin-1 receptor-associated kinase 1", "gene_name": "IRAK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y616-1", "protein_name": "Interleukin-1 receptor-associated kinase 3", "gene_name": "IRAK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15399-1", "protein_name": "Toll-like receptor 1", "gene_name": "TLR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y2C9-1", "protein_name": "Toll-like receptor 6", "gene_name": "TLR6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08571-1", "protein_name": "Monocyte differentiation antigen CD14", "gene_name": "CD14", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99836-1", "protein_name": "Myeloid differentiation primary response protein MyD88", "gene_name": "MYD88", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23297-1", "protein_name": "Protein S100-A1", "gene_name": "S100A1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P02671", "url": "https://www.uniprot.org/uniprotkb/P02671" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.10465784", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], 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}, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Thrombocyte HLA molecules retain nonrenewable endogenous peptides of megakaryocyte lineage and do not stimulate direct allocytotoxicity in vitro.", "journal": "Blood", "date": "2000-05-15", "authors": "Gouttefangeas C, Diehl M, Keilholz W, H\u00f6rnlein R F, Stevanovi\u0107 S, Rammensee H G", "reference": { "type": 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"gene_name": "ODC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07203-1", "protein_name": "Glutathione peroxidase 1", "gene_name": "GPX1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14770-1", "protein_name": "Platelet glycoprotein IX", "gene_name": "GP9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61978-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein K", "gene_name": "HNRNPK", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P02671", "url": "https://www.uniprot.org/uniprotkb/P02671" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.10807784", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 10 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Extracellular fibrinogen-binding protein, Efb, from Staphylococcus aureus blocks platelet aggregation due to its binding to the alpha-chain.", "journal": "J. Biol. Chem.", "date": "2001", "authors": "Palma M, Shannon O, Quezada H C, Berg A, Flock J I", "reference": { "type": "PubMed", "id": "11418620", "url": "https://pubmed.ncbi.nlm.nih.gov/11418620" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P02671-1", "protein_name": "Fibrinogen alpha chain", "gene_name": "FGA", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P02671", "url": "https://www.uniprot.org/uniprotkb/P02671" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.11418620", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", 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}, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Fibrinogen stimulates macrophage chemokine secretion through toll-like receptor 4.", "journal": "Journal of immunology (Baltimore, Md. : 1950)", "date": "2001", "authors": "Smiley ST, King JA, Hancock WW", "reference": { "type": "PubMed", "id": "11509636", "url": "https://pubmed.ncbi.nlm.nih.gov/11509636" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P02671-1", "protein_name": "Fibrinogen alpha chain", "gene_name": "FGA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06702-1", "protein_name": "Protein S100-A9", "gene_name": "S100A9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04114-1", "protein_name": "Apolipoprotein B-100", "gene_name": "APOB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09429-1", "protein_name": "High mobility group protein B1", "gene_name": "HMGB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02679-1", "protein_name": "Fibrinogen gamma chain", "gene_name": "FGG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IWL1-1", "protein_name": "Pulmonary surfactant-associated protein A2", "gene_name": "SFTPA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IWL2-1", "protein_name": "Pulmonary surfactant-associated protein A1", "gene_name": "SFTPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16671-1", "protein_name": "Platelet glycoprotein 4", "gene_name": "CD36", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60603-1", "protein_name": "Toll-like receptor 2", "gene_name": "TLR2", "tax_name": "Human" }, { "uniprot_canonical_ac": 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"count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "IRAK-4 as the central TIR signaling mediator in innate immunity.", "journal": "Trends in immunology", "date": "2002", "authors": "Suzuki N, Suzuki S, Yeh WC", "reference": { "type": "PubMed", "id": "12297423", "url": "https://pubmed.ncbi.nlm.nih.gov/12297423" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P02671-1", "protein_name": "Fibrinogen alpha chain", "gene_name": "FGA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06702-1", "protein_name": "Protein S100-A9", "gene_name": "S100A9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13233-1", "protein_name": "Mitogen-activated protein kinase kinase kinase 1", "gene_name": "MAP3K1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43187-1", "protein_name": "Interleukin-1 receptor-associated kinase-like 2", "gene_name": "IRAK2", "tax_name": "Human" }, 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"tax_name": "Human" }, { "uniprot_canonical_ac": "P05109-1", "protein_name": "Protein S100-A8", "gene_name": "S100A8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51617-1", "protein_name": "Interleukin-1 receptor-associated kinase 1", "gene_name": "IRAK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y616-1", "protein_name": "Interleukin-1 receptor-associated kinase 3", "gene_name": "IRAK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15399-1", "protein_name": "Toll-like receptor 1", "gene_name": "TLR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60602-1", "protein_name": "Toll-like receptor 5", "gene_name": "TLR5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BXR5-1", "protein_name": "Toll-like receptor 10", "gene_name": "TLR10", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y2C9-1", "protein_name": "Toll-like receptor 6", "gene_name": "TLR6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NR96-1", "protein_name": "Toll-like receptor 9", "gene_name": "TLR9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08571-1", "protein_name": "Monocyte differentiation antigen CD14", "gene_name": "CD14", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99836-1", "protein_name": "Myeloid differentiation primary response protein MyD88", "gene_name": "MYD88", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23297-1", "protein_name": "Protein S100-A1", "gene_name": "S100A1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P02671", "url": "https://www.uniprot.org/uniprotkb/P02671" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.12297423", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 30 } ], "sort_fields": [ 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"gene_name": "TLR6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08571-1", "protein_name": "Monocyte differentiation antigen CD14", "gene_name": "CD14", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99836-1", "protein_name": "Myeloid differentiation primary response protein MyD88", "gene_name": "MYD88", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23297-1", "protein_name": "Protein S100-A1", "gene_name": "S100A1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P02671", "url": "https://www.uniprot.org/uniprotkb/P02671" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.12447441", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 26 } ], "sort_fields": [ 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"uniprot_canonical_ac": "P02679-1", "protein_name": "Fibrinogen gamma chain", "gene_name": "FGG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NWZ3-1", "protein_name": "Interleukin-1 receptor-associated kinase 4", "gene_name": "IRAK4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6IA17-1", "protein_name": "Single Ig IL-1-related receptor", "gene_name": "SIGIRR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BQ95-1", "protein_name": "Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial", "gene_name": "ECSIT", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16671-1", "protein_name": "Platelet glycoprotein 4", "gene_name": "CD36", "tax_name": "Human" }, { "uniprot_canonical_ac": "A0A8V0XHS1-1", "protein_name": "Lymphocyte antigen 96", "gene_name": "LY96", "tax_name": "Chicken" }, { "uniprot_canonical_ac": "O60603-1", "protein_name": "Toll-like receptor 2", "gene_name": "TLR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00206-1", "protein_name": "Toll-like receptor 4", "gene_name": "TLR4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6Y9-1", "protein_name": "Lymphocyte antigen 96", "gene_name": "LY96", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYK1-1", "protein_name": "Toll-like receptor 7", "gene_name": "TLR7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06187-1", "protein_name": "Tyrosine-protein kinase BTK", "gene_name": "BTK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02675-1", "protein_name": "Fibrinogen beta chain", "gene_name": "FGB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05109-1", "protein_name": "Protein S100-A8", "gene_name": "S100A8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51617-1", "protein_name": "Interleukin-1 receptor-associated kinase 1", "gene_name": "IRAK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y616-1", "protein_name": "Interleukin-1 receptor-associated kinase 3", "gene_name": "IRAK3", "tax_name": "Human" }, { 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"gene_name": "CD14", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99836-1", "protein_name": "Myeloid differentiation primary response protein MyD88", "gene_name": "MYD88", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23297-1", "protein_name": "Protein S100-A1", "gene_name": "S100A1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P02671", "url": "https://www.uniprot.org/uniprotkb/P02671" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.12447442", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 33 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 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IRAK-4 deficiency.", "journal": "Science (New York, N.Y.)", "date": "2003", "authors": "Picard C, Puel A, Bonnet M, Ku CL, Bustamante J, Yang K, Soudais C, Dupuis S, Feinberg J, Fieschi C, Elbim C, Hitchcock R, Lammas D, Davies G, Al-Ghonaium A, Al-Rayes H, Al-Jumaah S, Al-Hajjar S, Al-Mohsen IZ, Frayha HH, Rucker R, Hawn TR, Aderem A, Tufenkeji H, Haraguchi S, Day NK, Good RA, Gougerot-Pocidalo MA, Ozinsky A, Casanova JL", "reference": { "type": "PubMed", "id": "12637671", "url": "https://pubmed.ncbi.nlm.nih.gov/12637671" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P02671-1", "protein_name": "Fibrinogen alpha chain", "gene_name": "FGA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06702-1", "protein_name": "Protein S100-A9", "gene_name": "S100A9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P58753-1", "protein_name": "Toll/interleukin-1 receptor domain-containing adapter protein", "gene_name": "TIRAP", "tax_name": "Human" }, { 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"Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 22, "end_pos": 22, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P02671", "url": "https://www.uniprot.org/uniprotkb/P02671" }, { "database": "PubMed", "id": "16807684", "url": "https://pubmed.ncbi.nlm.nih.gov/16807684" }, { "database": "iPTMnet", "id": "P02671", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P02671" }, { "database": "PubMed", "id": "12729597", "url": "https://pubmed.ncbi.nlm.nih.gov/12729597" }, { "database": "PubMed", "id": "19117447", "url": "https://pubmed.ncbi.nlm.nih.gov/19117447" }, { "database": "PubMed", "id": "20058876", "url": "https://pubmed.ncbi.nlm.nih.gov/20058876" } ], "site_lbl": "Ser22", "uniprot_canonical_ac": "P02671-1" } ], "record_id": "pubmed.12729597", "abstract": "", "glycosylation": [], "mutagenesis": [], 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}, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Direct binding of Toll-like receptor 2 to zymosan, and zymosan-induced NF-kappa B activation and TNF-alpha secretion are down-regulated by lung collectin surfactant protein A.", "journal": "Journal of immunology (Baltimore, Md. : 1950)", "date": "2003", "authors": "Sato M, Sano H, Iwaki D, Kudo K, Konishi M, Takahashi H, Takahashi T, Imaizumi H, Asai Y, Kuroki Y", "reference": { "type": "PubMed", "id": "12817025", "url": "https://pubmed.ncbi.nlm.nih.gov/12817025" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P02671-1", "protein_name": "Fibrinogen alpha chain", "gene_name": "FGA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06702-1", "protein_name": "Protein S100-A9", "gene_name": "S100A9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04114-1", "protein_name": "Apolipoprotein B-100", "gene_name": "APOB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09429-1", "protein_name": "High mobility group protein B1", "gene_name": "HMGB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02679-1", "protein_name": "Fibrinogen gamma chain", "gene_name": "FGG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IWL1-1", "protein_name": "Pulmonary surfactant-associated protein A2", "gene_name": "SFTPA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IWL2-1", "protein_name": "Pulmonary surfactant-associated protein A1", "gene_name": "SFTPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16671-1", "protein_name": "Platelet glycoprotein 4", "gene_name": "CD36", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60603-1", "protein_name": "Toll-like receptor 2", "gene_name": "TLR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57764-1", "protein_name": "Gasdermin-D", "gene_name": "GSDMD", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60443-1", "protein_name": "Gasdermin-E", "gene_name": "GSDME", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00206-1", "protein_name": "Toll-like receptor 4", "gene_name": "TLR4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P18428-1", "protein_name": "Lipopolysaccharide-binding protein", "gene_name": "LBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6Y9-1", "protein_name": "Lymphocyte antigen 96", "gene_name": "LY96", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35247-1", "protein_name": "Pulmonary surfactant-associated protein D", "gene_name": "SFTPD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYK1-1", "protein_name": "Toll-like receptor 7", "gene_name": "TLR7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02675-1", "protein_name": "Fibrinogen beta chain", "gene_name": "FGB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05109-1", "protein_name": "Protein S100-A8", "gene_name": "S100A8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15399-1", "protein_name": "Toll-like receptor 1", "gene_name": "TLR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y2C9-1", "protein_name": "Toll-like receptor 6", "gene_name": "TLR6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08571-1", "protein_name": "Monocyte differentiation antigen CD14", "gene_name": "CD14", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23297-1", "protein_name": "Protein S100-A1", "gene_name": "S100A1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P02671", "url": "https://www.uniprot.org/uniprotkb/P02671" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.12817025", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 22 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 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sapiens [9606]" } ], "record_id": "pubmed.1457396", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", 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{ "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Toll-like receptors in innate immunity.", "journal": "International immunology", "date": "2005", "authors": "Takeda K, Akira S", "reference": { "type": "PubMed", "id": "15585605", "url": "https://pubmed.ncbi.nlm.nih.gov/15585605" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P02671-1", "protein_name": "Fibrinogen alpha chain", "gene_name": "FGA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06702-1", "protein_name": "Protein S100-A9", "gene_name": "S100A9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13233-1", "protein_name": "Mitogen-activated protein kinase kinase kinase 1", "gene_name": "MAP3K1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43187-1", "protein_name": "Interleukin-1 receptor-associated kinase-like 2", "gene_name": "IRAK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P58753-1", "protein_name": "Toll/interleukin-1 receptor domain-containing adapter protein", "gene_name": "TIRAP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y4K3-1", "protein_name": "TNF receptor-associated factor 6", "gene_name": "TRAF6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09429-1", "protein_name": "High 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SP-A and SP-D: structure, function and receptors.", "journal": "Molecular immunology", "date": "2006", "authors": "Kishore U, Greenhough TJ, Waters P, Shrive AK, Ghai R, Kamran MF, Bernal AL, Reid KB, Madan T, Chakraborty T", "reference": { "type": "PubMed", "id": "16213021", "url": "https://pubmed.ncbi.nlm.nih.gov/16213021" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P02671-1", "protein_name": "Fibrinogen alpha chain", "gene_name": "FGA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06702-1", "protein_name": "Protein S100-A9", "gene_name": "S100A9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04114-1", "protein_name": "Apolipoprotein B-100", "gene_name": "APOB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09429-1", "protein_name": "High mobility group protein B1", "gene_name": "HMGB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9P1W8-1", "protein_name": "Signal-regulatory protein gamma", "gene_name": "SIRPG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q08722-1", "protein_name": "Leukocyte surface antigen CD47", "gene_name": "CD47", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02679-1", "protein_name": "Fibrinogen gamma chain", "gene_name": "FGG", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75563-1", "protein_name": "Src kinase-associated phosphoprotein 2", "gene_name": "SKAP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IWL1-1", "protein_name": "Pulmonary surfactant-associated protein A2", "gene_name": "SFTPA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q05397-1", "protein_name": "Focal adhesion kinase 1", "gene_name": "PTK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IWL2-1", "protein_name": "Pulmonary surfactant-associated protein A1", "gene_name": "SFTPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29350-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 6", "gene_name": "PTPN6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16671-1", "protein_name": "Platelet glycoprotein 4", "gene_name": "CD36", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60603-1", "protein_name": "Toll-like receptor 2", "gene_name": "TLR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57764-1", "protein_name": "Gasdermin-D", "gene_name": "GSDMD", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60443-1", "protein_name": "Gasdermin-E", "gene_name": "GSDME", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00206-1", "protein_name": "Toll-like receptor 4", "gene_name": "TLR4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P18428-1", "protein_name": "Lipopolysaccharide-binding protein", "gene_name": "LBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6Y9-1", "protein_name": "Lymphocyte antigen 96", "gene_name": "LY96", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00241-1", "protein_name": "Signal-regulatory protein beta-1", "gene_name": "SIRPB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35247-1", "protein_name": "Pulmonary surfactant-associated protein D", "gene_name": "SFTPD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYK1-1", "protein_name": "Toll-like receptor 7", "gene_name": "TLR7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06124-2", "protein_name": "Tyrosine-protein phosphatase non-receptor type 11", "gene_name": "PTPN11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02675-1", "protein_name": "Fibrinogen beta chain", "gene_name": "FGB", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15117-1", "protein_name": "FYN-binding protein 1", "gene_name": "FYB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05109-1", "protein_name": "Protein S100-A8", "gene_name": "S100A8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43914-1", "protein_name": "TYRO protein tyrosine kinase-binding protein", "gene_name": "TYROBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15399-1", "protein_name": "Toll-like receptor 1", "gene_name": "TLR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y2C9-1", "protein_name": "Toll-like receptor 6", "gene_name": "TLR6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78324-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type substrate 1", "gene_name": "SIRPA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08571-1", "protein_name": "Monocyte differentiation antigen CD14", "gene_name": "CD14", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14289-1", "protein_name": "Protein-tyrosine kinase 2-beta", "gene_name": "PTK2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23297-1", "protein_name": "Protein S100-A1", "gene_name": "S100A1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P02671", "url": "https://www.uniprot.org/uniprotkb/P02671" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.16213021", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 33 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": 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Balandraud Nathalie, Guis Sandrine, Nogueira Leonor, Svensson Bj\u00f6rn, Cantagrel Alain, Serre Guy, Roudier Jean", "reference": { "type": "PubMed", "id": "16255019", "url": "https://pubmed.ncbi.nlm.nih.gov/16255019" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P02671-1", "protein_name": "Fibrinogen alpha chain", "gene_name": "FGA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02675-1", "protein_name": "Fibrinogen beta chain", "gene_name": "FGB", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P02671", "url": "https://www.uniprot.org/uniprotkb/P02671" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.16255019", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Fibrinogen Lima: a homozygous dysfibrinogen with an A alpha-arginine-141 to serine substitution associated with extra N-glycosylation at A alpha-asparagine-139. Impaired fibrin gel formation but normal fibrin-facilitated plasminogen activation catalyzed by tissue-type plasminogen activator.", "journal": "The Journal of clinical investigation", "date": "1992", "authors": "Maekawa H, Yamazumi K, Muramatsu S, Kaneko M, Hirata H, Takahashi N, Arocha-Pinango CL, Rodriguez S, Nagy H, Perez-Requejo JL, et al.", "reference": { "type": "PubMed", "id": "1634621", "url": "https://pubmed.ncbi.nlm.nih.gov/1634621" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P02671-1", "protein_name": "Fibrinogen alpha chain", "gene_name": "FGA", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P02671", "url": "https://www.uniprot.org/uniprotkb/P02671" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.1634621", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "MyD88 adapter-like (Mal) is phosphorylated by Bruton's tyrosine kinase during TLR2 and TLR4 signal transduction.", "journal": "The Journal of biological chemistry", "date": "2006", "authors": "Gray P, Dunne A, Brikos C, Jefferies CA, Doyle SL, O'Neill LA", "reference": { "type": "PubMed", "id": "16439361", "url": 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"protein_name": "Toll-like receptor 1", "gene_name": "TLR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y2C9-1", "protein_name": "Toll-like receptor 6", "gene_name": "TLR6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08571-1", "protein_name": "Monocyte differentiation antigen CD14", "gene_name": "CD14", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99836-1", "protein_name": "Myeloid differentiation primary response protein MyD88", "gene_name": "MYD88", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23297-1", "protein_name": "Protein S100-A1", "gene_name": "S100A1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P02671", "url": "https://www.uniprot.org/uniprotkb/P02671" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 106, "end_pos": 106, "kinase_uniprot_canonical_ac": "Q06187-1", "kinase_gene_name": "BTK", "residue": "Tyr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P58753", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P58753" }, { "database": "PubMed", "id": "16439361", "url": "https://pubmed.ncbi.nlm.nih.gov/16439361" }, { "database": "PubMed", "id": "24840642", "url": "https://pubmed.ncbi.nlm.nih.gov/24840642" } ], "site_lbl": "Tyr106", "uniprot_canonical_ac": "P58753-1" }, { "start_pos": 187, "end_pos": 187, "kinase_uniprot_canonical_ac": "Q06187-1", "kinase_gene_name": "BTK", "residue": "Tyr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P58753", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P58753" }, { "database": "PubMed", "id": "16439361", "url": "https://pubmed.ncbi.nlm.nih.gov/16439361" } ], "site_lbl": "Tyr187", "uniprot_canonical_ac": "P58753-1" }, { "start_pos": 86, "end_pos": 86, "kinase_uniprot_canonical_ac": "Q06187-1", "kinase_gene_name": "BTK", "residue": "Tyr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P58753", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P58753" }, { "database": "PubMed", "id": "16439361", "url": "https://pubmed.ncbi.nlm.nih.gov/16439361" }, { "database": "PubMed", "id": "24840642", "url": "https://pubmed.ncbi.nlm.nih.gov/24840642" } ], "site_lbl": "Tyr86", "uniprot_canonical_ac": "P58753-1" } ], "record_id": "pubmed.16439361", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 26 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Phosphoinositide-mediated adaptor recruitment controls Toll-like receptor signaling.", "journal": "Cell", "date": "2006", "authors": "Kagan JC, Medzhitov R", "reference": { "type": "PubMed", "id": "16751103", "url": "https://pubmed.ncbi.nlm.nih.gov/16751103" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P02671-1", "protein_name": "Fibrinogen alpha chain", "gene_name": "FGA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06702-1", "protein_name": "Protein S100-A9", "gene_name": "S100A9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13233-1", "protein_name": "Mitogen-activated protein kinase kinase kinase 1", "gene_name": "MAP3K1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43187-1", "protein_name": "Interleukin-1 receptor-associated kinase-like 2", "gene_name": "IRAK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P58753-1", "protein_name": "Toll/interleukin-1 receptor domain-containing adapter protein", "gene_name": "TIRAP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y4K3-1", "protein_name": "TNF receptor-associated factor 6", "gene_name": "TRAF6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09429-1", "protein_name": "High mobility group protein B1", "gene_name": "HMGB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15524-1", "protein_name": "Suppressor of cytokine signaling 1", "gene_name": "SOCS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02679-1", "protein_name": "Fibrinogen gamma chain", "gene_name": "FGG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NWZ3-1", "protein_name": "Interleukin-1 receptor-associated kinase 4", "gene_name": "IRAK4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IWL1-1", "protein_name": "Pulmonary surfactant-associated protein A2", "gene_name": "SFTPA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6IA17-1", "protein_name": "Single Ig IL-1-related receptor", "gene_name": "SIGIRR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IWL2-1", "protein_name": "Pulmonary surfactant-associated protein A1", "gene_name": "SFTPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BQ95-1", "protein_name": "Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial", "gene_name": "ECSIT", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16671-1", "protein_name": "Platelet glycoprotein 4", "gene_name": "CD36", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99467-1", "protein_name": "CD180 antigen", "gene_name": "CD180", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95711-1", "protein_name": "Lymphocyte antigen 86", "gene_name": "LY86", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60603-1", "protein_name": "Toll-like receptor 2", "gene_name": "TLR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00206-1", "protein_name": "Toll-like receptor 4", "gene_name": "TLR4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P18428-1", "protein_name": "Lipopolysaccharide-binding protein", "gene_name": "LBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6Y9-1", "protein_name": "Lymphocyte antigen 96", "gene_name": "LY96", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35247-1", "protein_name": "Pulmonary surfactant-associated protein D", "gene_name": "SFTPD", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29074-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 4", "gene_name": "PTPN4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11215-1", "protein_name": "Integrin alpha-M", "gene_name": "ITGAM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06187-1", "protein_name": "Tyrosine-protein kinase BTK", "gene_name": "BTK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P50570-1", "protein_name": "Dynamin-2", "gene_name": "DNM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16885-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2", "gene_name": "PLCG2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02675-1", "protein_name": "Fibrinogen beta chain", "gene_name": "FGB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05109-1", "protein_name": "Protein S100-A8", "gene_name": "S100A8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P17213-1", "protein_name": "Bactericidal permeability-increasing protein", "gene_name": "BPI", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51617-1", "protein_name": "Interleukin-1 receptor-associated kinase 1", "gene_name": "IRAK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y616-1", "protein_name": "Interleukin-1 receptor-associated kinase 3", "gene_name": "IRAK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15399-1", "protein_name": "Toll-like receptor 1", "gene_name": "TLR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y2C9-1", "protein_name": "Toll-like receptor 6", "gene_name": "TLR6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08571-1", "protein_name": "Monocyte differentiation antigen CD14", "gene_name": "CD14", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q05193-1", "protein_name": "Dynamin-1", "gene_name": "DNM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99836-1", "protein_name": "Myeloid differentiation primary response protein MyD88", "gene_name": "MYD88", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ16-1", "protein_name": "Dynamin-3", "gene_name": "DNM3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23297-1", "protein_name": "Protein S100-A1", "gene_name": "S100A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86XR7-1", "protein_name": "TIR domain-containing adapter molecule 2", "gene_name": "TICAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05107-1", "protein_name": "Integrin beta-2", "gene_name": "ITGB2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P02671", "url": "https://www.uniprot.org/uniprotkb/P02671" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.16751103", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 41 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Surfactant protein A directly interacts with TLR4 and MD-2 and regulates inflammatory cellular response. Importance of supratrimeric oligomerization.", "journal": "The Journal of biological chemistry", "date": "2006", "authors": "Yamada C, Sano H, Shimizu T, Mitsuzawa H, Nishitani C, Himi T, Kuroki Y", "reference": { "type": "PubMed", "id": "16754682", "url": "https://pubmed.ncbi.nlm.nih.gov/16754682" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P02671-1", "protein_name": "Fibrinogen alpha chain", "gene_name": "FGA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06702-1", "protein_name": "Protein S100-A9", "gene_name": "S100A9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04114-1", "protein_name": "Apolipoprotein B-100", "gene_name": "APOB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09429-1", "protein_name": "High mobility group protein B1", "gene_name": "HMGB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02679-1", "protein_name": "Fibrinogen gamma chain", "gene_name": "FGG", "tax_name": "Human" }, { "uniprot_canonical_ac": 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"uniprot_canonical_ac": "Q9Y6Y9-1", "protein_name": "Lymphocyte antigen 96", "gene_name": "LY96", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35247-1", "protein_name": "Pulmonary surfactant-associated protein D", "gene_name": "SFTPD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYK1-1", "protein_name": "Toll-like receptor 7", "gene_name": "TLR7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02675-1", "protein_name": "Fibrinogen beta chain", "gene_name": "FGB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05109-1", "protein_name": "Protein S100-A8", "gene_name": "S100A8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15399-1", "protein_name": "Toll-like receptor 1", "gene_name": "TLR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y2C9-1", "protein_name": "Toll-like receptor 6", "gene_name": "TLR6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08571-1", "protein_name": "Monocyte differentiation antigen CD14", "gene_name": "CD14", "tax_name": 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"Ohya M, Nishitani C, Sano H, Yamada C, Mitsuzawa H, Shimizu T, Saito T, Smith K, Crouch E, Kuroki Y", "reference": { "type": "PubMed", "id": "16834340", "url": "https://pubmed.ncbi.nlm.nih.gov/16834340" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P02671-1", "protein_name": "Fibrinogen alpha chain", "gene_name": "FGA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06702-1", "protein_name": "Protein S100-A9", "gene_name": "S100A9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04114-1", "protein_name": "Apolipoprotein B-100", "gene_name": "APOB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09429-1", "protein_name": "High mobility group protein B1", "gene_name": "HMGB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02679-1", "protein_name": "Fibrinogen gamma chain", "gene_name": "FGG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IWL1-1", "protein_name": "Pulmonary surfactant-associated protein A2", "gene_name": "SFTPA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IWL2-1", "protein_name": "Pulmonary surfactant-associated protein A1", "gene_name": "SFTPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16671-1", "protein_name": "Platelet glycoprotein 4", "gene_name": "CD36", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60603-1", "protein_name": "Toll-like receptor 2", "gene_name": "TLR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57764-1", "protein_name": "Gasdermin-D", "gene_name": "GSDMD", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60443-1", "protein_name": "Gasdermin-E", "gene_name": "GSDME", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00206-1", "protein_name": "Toll-like receptor 4", "gene_name": "TLR4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P18428-1", "protein_name": "Lipopolysaccharide-binding protein", "gene_name": "LBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6Y9-1", "protein_name": "Lymphocyte antigen 96", "gene_name": "LY96", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35247-1", "protein_name": "Pulmonary surfactant-associated protein D", "gene_name": "SFTPD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYK1-1", "protein_name": "Toll-like receptor 7", "gene_name": "TLR7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02675-1", "protein_name": "Fibrinogen beta chain", "gene_name": "FGB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05109-1", "protein_name": "Protein S100-A8", "gene_name": "S100A8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15399-1", "protein_name": "Toll-like receptor 1", "gene_name": "TLR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y2C9-1", "protein_name": "Toll-like receptor 6", "gene_name": "TLR6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08571-1", "protein_name": "Monocyte differentiation antigen CD14", "gene_name": "CD14", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23297-1", "protein_name": "Protein S100-A1", "gene_name": "S100A1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P02671", "url": "https://www.uniprot.org/uniprotkb/P02671" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.16834340", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 22 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, 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"count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The fibrinogen Aalpha R16C mutation results in fibrinolytic resistance.", "journal": "British journal of haematology", "date": "2006", "authors": "Flood VH, Al-Mondhiry HA, Farrell DH", "reference": { "type": "PubMed", "id": "16846481", "url": "https://pubmed.ncbi.nlm.nih.gov/16846481" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P02671-1", "protein_name": "Fibrinogen alpha chain", "gene_name": "FGA", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P02671", "url": "https://www.uniprot.org/uniprotkb/P02671" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.16846481", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The extracellular release of HMGB1 during apoptotic cell death.", "journal": "American journal of physiology. Cell physiology", "date": "2006", "authors": "Bell CW, Jiang W, Reich CF 3rd, Pisetsky DS", "reference": { "type": "PubMed", "id": "16855214", "url": "https://pubmed.ncbi.nlm.nih.gov/16855214" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P02671-1", "protein_name": "Fibrinogen alpha chain", "gene_name": "FGA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06702-1", "protein_name": "Protein S100-A9", "gene_name": "S100A9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04114-1", "protein_name": "Apolipoprotein B-100", "gene_name": "APOB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09429-1", "protein_name": "High mobility group protein B1", "gene_name": "HMGB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02679-1", "protein_name": "Fibrinogen gamma chain", "gene_name": "FGG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IWL1-1", "protein_name": "Pulmonary surfactant-associated protein A2", "gene_name": "SFTPA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IWL2-1", "protein_name": "Pulmonary surfactant-associated protein A1", "gene_name": "SFTPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16671-1", "protein_name": "Platelet glycoprotein 4", "gene_name": "CD36", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60603-1", "protein_name": "Toll-like receptor 2", "gene_name": "TLR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57764-1", "protein_name": "Gasdermin-D", "gene_name": "GSDMD", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60443-1", "protein_name": "Gasdermin-E", "gene_name": "GSDME", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00206-1", "protein_name": "Toll-like receptor 4", "gene_name": "TLR4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P18428-1", "protein_name": "Lipopolysaccharide-binding protein", "gene_name": "LBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6Y9-1", "protein_name": "Lymphocyte antigen 96", "gene_name": "LY96", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35247-1", "protein_name": "Pulmonary surfactant-associated protein D", "gene_name": "SFTPD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYK1-1", "protein_name": "Toll-like receptor 7", "gene_name": "TLR7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02675-1", "protein_name": "Fibrinogen beta chain", "gene_name": "FGB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05109-1", "protein_name": "Protein S100-A8", "gene_name": "S100A8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15399-1", "protein_name": "Toll-like receptor 1", "gene_name": "TLR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y2C9-1", "protein_name": "Toll-like receptor 6", "gene_name": "TLR6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08571-1", "protein_name": "Monocyte differentiation antigen CD14", "gene_name": "CD14", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23297-1", "protein_name": "Protein S100-A1", "gene_name": "S100A1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P02671", "url": "https://www.uniprot.org/uniprotkb/P02671" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.16855214", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 22 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, 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"n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "HMGB1 signals through toll-like receptor (TLR) 4 and TLR2.", "journal": "Shock (Augusta, Ga.)", "date": "2006", "authors": "Yu M, Wang H, Ding A, Golenbock DT, Latz E, Czura CJ, Fenton MJ, Tracey KJ, Yang H", "reference": { "type": "PubMed", "id": "16878026", "url": "https://pubmed.ncbi.nlm.nih.gov/16878026" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P02671-1", "protein_name": "Fibrinogen alpha chain", "gene_name": "FGA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06702-1", "protein_name": "Protein S100-A9", "gene_name": "S100A9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04114-1", "protein_name": "Apolipoprotein B-100", "gene_name": "APOB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09429-1", "protein_name": "High mobility group protein B1", "gene_name": "HMGB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02679-1", "protein_name": "Fibrinogen gamma chain", "gene_name": "FGG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IWL1-1", "protein_name": "Pulmonary surfactant-associated protein A2", "gene_name": "SFTPA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IWL2-1", "protein_name": "Pulmonary surfactant-associated protein A1", "gene_name": "SFTPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16671-1", "protein_name": "Platelet glycoprotein 4", "gene_name": "CD36", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60603-1", "protein_name": "Toll-like receptor 2", "gene_name": "TLR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57764-1", "protein_name": "Gasdermin-D", "gene_name": "GSDMD", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60443-1", "protein_name": "Gasdermin-E", "gene_name": "GSDME", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00206-1", "protein_name": "Toll-like receptor 4", "gene_name": "TLR4", "tax_name": "Human" }, { "uniprot_canonical_ac": 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"uniprot_canonical_ac": "P08571-1", "protein_name": "Monocyte differentiation antigen CD14", "gene_name": "CD14", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23297-1", "protein_name": "Protein S100-A1", "gene_name": "S100A1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P02671", "url": "https://www.uniprot.org/uniprotkb/P02671" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.16878026", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 22 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Essential role of IRAK-4 protein and its kinase activity in Toll-like receptor-mediated immune responses but not in TCR signaling.", "journal": "The Journal of experimental medicine", "date": "2007", "authors": "Kawagoe T, Sato S, Jung A, Yamamoto M, Matsui K, Kato H, Uematsu S, Takeuchi O, Akira S", "reference": { "type": "PubMed", "id": "17485511", "url": "https://pubmed.ncbi.nlm.nih.gov/17485511" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P02671-1", "protein_name": "Fibrinogen alpha chain", "gene_name": "FGA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06702-1", "protein_name": "Protein S100-A9", "gene_name": "S100A9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13233-1", "protein_name": "Mitogen-activated protein kinase kinase kinase 1", "gene_name": "MAP3K1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43187-1", "protein_name": "Interleukin-1 receptor-associated kinase-like 2", "gene_name": "IRAK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P58753-1", "protein_name": "Toll/interleukin-1 receptor domain-containing adapter protein", "gene_name": "TIRAP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y4K3-1", "protein_name": "TNF receptor-associated factor 6", "gene_name": "TRAF6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09429-1", "protein_name": "High mobility group protein B1", "gene_name": "HMGB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15524-1", "protein_name": "Suppressor of cytokine signaling 1", "gene_name": "SOCS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02679-1", "protein_name": "Fibrinogen gamma chain", "gene_name": "FGG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NWZ3-1", "protein_name": "Interleukin-1 receptor-associated kinase 4", "gene_name": "IRAK4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6IA17-1", "protein_name": "Single Ig IL-1-related receptor", "gene_name": "SIGIRR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BQ95-1", "protein_name": "Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial", "gene_name": "ECSIT", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16671-1", "protein_name": "Platelet glycoprotein 4", "gene_name": "CD36", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60603-1", "protein_name": "Toll-like receptor 2", "gene_name": "TLR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00206-1", "protein_name": "Toll-like receptor 4", "gene_name": "TLR4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6Y9-1", "protein_name": "Lymphocyte antigen 96", "gene_name": "LY96", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYK1-1", "protein_name": "Toll-like receptor 7", "gene_name": "TLR7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06187-1", "protein_name": "Tyrosine-protein kinase BTK", "gene_name": "BTK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02675-1", "protein_name": "Fibrinogen beta chain", "gene_name": "FGB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05109-1", "protein_name": "Protein S100-A8", "gene_name": "S100A8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51617-1", "protein_name": "Interleukin-1 receptor-associated kinase 1", "gene_name": "IRAK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y616-1", "protein_name": "Interleukin-1 receptor-associated kinase 3", "gene_name": "IRAK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15399-1", "protein_name": "Toll-like receptor 1", "gene_name": "TLR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60602-1", "protein_name": "Toll-like receptor 5", "gene_name": "TLR5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BXR5-1", "protein_name": "Toll-like receptor 10", "gene_name": "TLR10", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y2C9-1", "protein_name": "Toll-like receptor 6", "gene_name": "TLR6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NR96-1", "protein_name": "Toll-like receptor 9", "gene_name": "TLR9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08571-1", "protein_name": "Monocyte differentiation antigen CD14", "gene_name": "CD14", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99836-1", "protein_name": "Myeloid differentiation primary response protein MyD88", "gene_name": "MYD88", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23297-1", "protein_name": "Protein S100-A1", "gene_name": "S100A1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P02671", "url": "https://www.uniprot.org/uniprotkb/P02671" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.17485511", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 30 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "A dimer of the Toll-like receptor 4 cytoplasmic domain provides a specific scaffold for the recruitment of signalling adaptor proteins.", "journal": "PloS one", "date": "2007", "authors": "Nunez Miguel R, Wong J, Westoll JF, Brooks HJ, O'Neill LA, Gay NJ, Bryant CE, Monie TP", "reference": { "type": "PubMed", "id": "17726518", "url": "https://pubmed.ncbi.nlm.nih.gov/17726518" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P02671-1", "protein_name": "Fibrinogen alpha chain", "gene_name": "FGA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06702-1", "protein_name": "Protein S100-A9", "gene_name": "S100A9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13233-1", "protein_name": "Mitogen-activated protein kinase kinase kinase 1", "gene_name": "MAP3K1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43187-1", "protein_name": "Interleukin-1 receptor-associated kinase-like 2", "gene_name": "IRAK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P58753-1", "protein_name": "Toll/interleukin-1 receptor domain-containing adapter protein", "gene_name": "TIRAP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y4K3-1", "protein_name": "TNF receptor-associated factor 6", "gene_name": "TRAF6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09429-1", "protein_name": "High mobility group protein B1", "gene_name": "HMGB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15524-1", "protein_name": "Suppressor of cytokine signaling 1", "gene_name": "SOCS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02679-1", "protein_name": "Fibrinogen gamma chain", "gene_name": "FGG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NWZ3-1", "protein_name": "Interleukin-1 receptor-associated kinase 4", "gene_name": "IRAK4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6IA17-1", "protein_name": "Single Ig IL-1-related receptor", "gene_name": "SIGIRR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BQ95-1", "protein_name": "Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial", "gene_name": "ECSIT", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16671-1", "protein_name": "Platelet glycoprotein 4", "gene_name": "CD36", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60603-1", "protein_name": "Toll-like receptor 2", "gene_name": "TLR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00206-1", "protein_name": "Toll-like receptor 4", "gene_name": "TLR4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6Y9-1", "protein_name": "Lymphocyte antigen 96", "gene_name": "LY96", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06187-1", "protein_name": "Tyrosine-protein kinase BTK", "gene_name": "BTK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02675-1", "protein_name": "Fibrinogen beta chain", "gene_name": "FGB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05109-1", "protein_name": "Protein S100-A8", "gene_name": "S100A8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51617-1", "protein_name": "Interleukin-1 receptor-associated kinase 1", "gene_name": "IRAK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y616-1", "protein_name": "Interleukin-1 receptor-associated kinase 3", "gene_name": "IRAK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15399-1", "protein_name": "Toll-like receptor 1", "gene_name": "TLR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y2C9-1", "protein_name": "Toll-like receptor 6", "gene_name": "TLR6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08571-1", "protein_name": "Monocyte differentiation antigen CD14", "gene_name": "CD14", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99836-1", "protein_name": "Myeloid differentiation primary response protein MyD88", "gene_name": "MYD88", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23297-1", "protein_name": "Protein S100-A1", "gene_name": "S100A1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P02671", "url": "https://www.uniprot.org/uniprotkb/P02671" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.17726518", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 26 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Mrp8 and Mrp14 are endogenous activators of Toll-like receptor 4, promoting lethal, endotoxin-induced shock.", "journal": "Nature medicine", "date": "2007", "authors": "Vogl T, Tenbrock K, Ludwig S, Leukert N, Ehrhardt C, van Zoelen MA, Nacken W, Foell D, van der Poll T, Sorg C, Roth J", "reference": { "type": "PubMed", "id": "17767165", "url": "https://pubmed.ncbi.nlm.nih.gov/17767165" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P02671-1", "protein_name": "Fibrinogen alpha chain", "gene_name": "FGA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06702-1", "protein_name": "Protein S100-A9", "gene_name": "S100A9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04114-1", "protein_name": "Apolipoprotein B-100", "gene_name": "APOB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09429-1", "protein_name": "High mobility group protein B1", "gene_name": "HMGB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P31725-1", "protein_name": "Protein S100-A9", "gene_name": "S100a9", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "P02679-1", "protein_name": "Fibrinogen gamma chain", "gene_name": "FGG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IWL1-1", "protein_name": "Pulmonary surfactant-associated protein A2", "gene_name": "SFTPA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27005-1", "protein_name": "Protein S100-A8", "gene_name": "S100a8", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IWL2-1", "protein_name": "Pulmonary surfactant-associated protein A1", "gene_name": "SFTPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16671-1", "protein_name": "Platelet glycoprotein 4", "gene_name": "CD36", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60603-1", "protein_name": "Toll-like receptor 2", "gene_name": "TLR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57764-1", "protein_name": "Gasdermin-D", "gene_name": "GSDMD", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60443-1", "protein_name": "Gasdermin-E", "gene_name": "GSDME", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00206-1", "protein_name": "Toll-like 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"Toll-like receptor 6", "gene_name": "TLR6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08571-1", "protein_name": "Monocyte differentiation antigen CD14", "gene_name": "CD14", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23297-1", "protein_name": "Protein S100-A1", "gene_name": "S100A1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P02671", "url": "https://www.uniprot.org/uniprotkb/P02671" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.17767165", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 24 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": 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"date": "2007", "authors": "Ku CL, von Bernuth H, Picard C, Zhang SY, Chang HH, Yang K, Chrabieh M, Issekutz AC, Cunningham CK, Gallin J, Holland SM, Roifman C, Ehl S, Smart J, Tang M, Barrat FJ, Levy O, McDonald D, Day-Good NK, Miller R, Takada H, Hara T, Al-Hajjar S, Al-Ghonaium A, Speert D, Sanlaville D, Li X, Geissmann F, Vivier E, Marodi L, Garty BZ, Chapel H, Rodriguez-Gallego C, Bossuyt X, Abel L, Puel A, Casanova JL", "reference": { "type": "PubMed", "id": "17893200", "url": "https://pubmed.ncbi.nlm.nih.gov/17893200" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P02671-1", "protein_name": "Fibrinogen alpha chain", "gene_name": "FGA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06702-1", "protein_name": "Protein S100-A9", "gene_name": "S100A9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P58753-1", "protein_name": "Toll/interleukin-1 receptor domain-containing adapter protein", "gene_name": "TIRAP", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09429-1", "protein_name": "High mobility group protein B1", "gene_name": "HMGB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02679-1", "protein_name": "Fibrinogen gamma chain", "gene_name": "FGG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NWZ3-1", "protein_name": "Interleukin-1 receptor-associated kinase 4", "gene_name": "IRAK4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16671-1", "protein_name": "Platelet glycoprotein 4", "gene_name": "CD36", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60603-1", "protein_name": "Toll-like receptor 2", "gene_name": "TLR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00206-1", "protein_name": "Toll-like receptor 4", "gene_name": "TLR4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6Y9-1", "protein_name": "Lymphocyte antigen 96", "gene_name": "LY96", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06187-1", "protein_name": "Tyrosine-protein kinase BTK", "gene_name": "BTK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02675-1", "protein_name": "Fibrinogen beta chain", "gene_name": "FGB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05109-1", "protein_name": "Protein S100-A8", "gene_name": "S100A8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15399-1", "protein_name": "Toll-like receptor 1", "gene_name": "TLR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60602-1", "protein_name": "Toll-like receptor 5", "gene_name": "TLR5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BXR5-1", "protein_name": "Toll-like receptor 10", "gene_name": "TLR10", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y2C9-1", "protein_name": "Toll-like receptor 6", "gene_name": "TLR6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08571-1", "protein_name": "Monocyte differentiation antigen CD14", "gene_name": "CD14", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99836-1", "protein_name": "Myeloid differentiation primary response protein 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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kinase 1", "gene_name": "MAP3K1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43187-1", "protein_name": "Interleukin-1 receptor-associated kinase-like 2", "gene_name": "IRAK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P58753-1", "protein_name": "Toll/interleukin-1 receptor domain-containing adapter protein", "gene_name": "TIRAP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y4K3-1", "protein_name": "TNF receptor-associated factor 6", "gene_name": "TRAF6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09429-1", "protein_name": "High mobility group protein B1", "gene_name": "HMGB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15524-1", "protein_name": "Suppressor of cytokine signaling 1", "gene_name": "SOCS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02679-1", "protein_name": "Fibrinogen gamma chain", "gene_name": "FGG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NWZ3-1", "protein_name": "Interleukin-1 receptor-associated kinase 4", "gene_name": "IRAK4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6IA17-1", "protein_name": "Single Ig IL-1-related receptor", "gene_name": "SIGIRR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BQ95-1", "protein_name": "Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial", "gene_name": "ECSIT", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16671-1", "protein_name": "Platelet glycoprotein 4", "gene_name": "CD36", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60603-1", "protein_name": "Toll-like receptor 2", "gene_name": "TLR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00206-1", "protein_name": "Toll-like receptor 4", "gene_name": "TLR4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6Y9-1", "protein_name": "Lymphocyte antigen 96", "gene_name": "LY96", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06187-1", "protein_name": "Tyrosine-protein kinase BTK", "gene_name": "BTK", "tax_name": "Human" }, { 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"uniprot_canonical_ac": "P04114-1", "protein_name": "Apolipoprotein B-100", "gene_name": "APOB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09429-1", "protein_name": "High mobility group protein B1", "gene_name": "HMGB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02679-1", "protein_name": "Fibrinogen gamma chain", "gene_name": "FGG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IWL1-1", "protein_name": "Pulmonary surfactant-associated protein A2", "gene_name": "SFTPA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IWL2-1", "protein_name": "Pulmonary surfactant-associated protein A1", "gene_name": "SFTPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16671-1", "protein_name": "Platelet glycoprotein 4", "gene_name": "CD36", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60603-1", "protein_name": "Toll-like receptor 2", "gene_name": "TLR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57764-1", "protein_name": "Gasdermin-D", "gene_name": 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{ "uniprot_canonical_ac": "O00206-1", "protein_name": "Toll-like receptor 4", "gene_name": "TLR4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6Y9-1", "protein_name": "Lymphocyte antigen 96", "gene_name": "LY96", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06187-1", "protein_name": "Tyrosine-protein kinase BTK", "gene_name": "BTK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02675-1", "protein_name": "Fibrinogen beta chain", "gene_name": "FGB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05109-1", "protein_name": "Protein S100-A8", "gene_name": "S100A8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51617-1", "protein_name": "Interleukin-1 receptor-associated kinase 1", "gene_name": "IRAK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y616-1", "protein_name": "Interleukin-1 receptor-associated kinase 3", "gene_name": "IRAK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15399-1", "protein_name": "Toll-like receptor 1", "gene_name": 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"gene_name": "SFTPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16671-1", "protein_name": "Platelet glycoprotein 4", "gene_name": "CD36", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60603-1", "protein_name": "Toll-like receptor 2", "gene_name": "TLR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57764-1", "protein_name": "Gasdermin-D", "gene_name": "GSDMD", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60443-1", "protein_name": "Gasdermin-E", "gene_name": "GSDME", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00206-1", "protein_name": "Toll-like receptor 4", "gene_name": "TLR4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P18428-1", "protein_name": "Lipopolysaccharide-binding protein", "gene_name": "LBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6Y9-1", "protein_name": "Lymphocyte antigen 96", "gene_name": "LY96", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35247-1", "protein_name": "Pulmonary surfactant-associated protein D", 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of circulating and cell-associated components of the toll-like receptor 4 pathway by oxidized phospholipids.", "journal": "Arteriosclerosis, thrombosis, and vascular biology", "date": "2009", "authors": "von Schlieffen E, Oskolkova OV, Schabbauer G, Gruber F, Bluml S, Genest M, Kadl A, Marsik C, Knapp S, Chow J, Leitinger N, Binder BR, Bochkov VN", "reference": { "type": "PubMed", "id": "19112167", "url": "https://pubmed.ncbi.nlm.nih.gov/19112167" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P02671-1", "protein_name": "Fibrinogen alpha chain", "gene_name": "FGA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06702-1", "protein_name": "Protein S100-A9", "gene_name": "S100A9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04114-1", "protein_name": "Apolipoprotein B-100", "gene_name": "APOB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09429-1", "protein_name": "High mobility group protein B1", "gene_name": "HMGB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02679-1", "protein_name": "Fibrinogen gamma chain", "gene_name": "FGG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IWL1-1", "protein_name": "Pulmonary surfactant-associated protein A2", "gene_name": "SFTPA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IWL2-1", "protein_name": "Pulmonary surfactant-associated protein A1", "gene_name": "SFTPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16671-1", "protein_name": "Platelet glycoprotein 4", "gene_name": "CD36", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60603-1", "protein_name": "Toll-like receptor 2", "gene_name": "TLR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57764-1", "protein_name": "Gasdermin-D", "gene_name": "GSDMD", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60443-1", "protein_name": "Gasdermin-E", "gene_name": "GSDME", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00206-1", "protein_name": "Toll-like receptor 4", "gene_name": "TLR4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P18428-1", "protein_name": "Lipopolysaccharide-binding protein", "gene_name": "LBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6Y9-1", "protein_name": "Lymphocyte antigen 96", "gene_name": "LY96", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35247-1", "protein_name": "Pulmonary surfactant-associated protein D", "gene_name": "SFTPD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYK1-1", "protein_name": "Toll-like receptor 7", "gene_name": "TLR7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02675-1", "protein_name": "Fibrinogen beta chain", "gene_name": "FGB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05109-1", "protein_name": "Protein S100-A8", "gene_name": "S100A8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15399-1", "protein_name": "Toll-like receptor 1", "gene_name": "TLR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y2C9-1", "protein_name": "Toll-like receptor 6", "gene_name": "TLR6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08571-1", "protein_name": "Monocyte differentiation antigen CD14", "gene_name": "CD14", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23297-1", "protein_name": "Protein S100-A1", "gene_name": "S100A1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P02671", "url": "https://www.uniprot.org/uniprotkb/P02671" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.19112167", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 22 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { 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"sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Interleukin-1 receptor-associated kinase 2 is critical for lipopolysaccharide-mediated post-transcriptional control.", "journal": "The Journal of biological chemistry", "date": "2009", "authors": "Wan Y, Xiao H, Affolter J, Kim TW, Bulek K, Chaudhuri S, Carlson D, Hamilton T, Mazumder B, Stark GR, Thomas J, Li X", "reference": { "type": "PubMed", "id": "19224918", "url": "https://pubmed.ncbi.nlm.nih.gov/19224918" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P02671-1", "protein_name": "Fibrinogen alpha chain", "gene_name": "FGA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06702-1", "protein_name": "Protein S100-A9", "gene_name": "S100A9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13233-1", "protein_name": "Mitogen-activated protein kinase kinase kinase 1", "gene_name": "MAP3K1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43187-1", "protein_name": "Interleukin-1 receptor-associated kinase-like 2", "gene_name": "IRAK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P58753-1", "protein_name": "Toll/interleukin-1 receptor domain-containing adapter protein", "gene_name": "TIRAP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y4K3-1", "protein_name": "TNF receptor-associated factor 6", "gene_name": "TRAF6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09429-1", "protein_name": "High mobility group protein B1", "gene_name": "HMGB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15524-1", "protein_name": "Suppressor of cytokine signaling 1", "gene_name": "SOCS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02679-1", "protein_name": "Fibrinogen gamma chain", "gene_name": "FGG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NWZ3-1", "protein_name": "Interleukin-1 receptor-associated kinase 4", "gene_name": "IRAK4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6IA17-1", "protein_name": "Single Ig IL-1-related receptor", "gene_name": "SIGIRR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BQ95-1", "protein_name": "Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial", "gene_name": "ECSIT", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16671-1", "protein_name": "Platelet glycoprotein 4", "gene_name": "CD36", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62985-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XHS1-1", "protein_name": "Lymphocyte antigen 96", "gene_name": "LY96", "tax_name": "Chicken" }, { "uniprot_canonical_ac": "O60603-1", "protein_name": "Toll-like receptor 2", "gene_name": "TLR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00206-1", "protein_name": "Toll-like receptor 4", "gene_name": "TLR4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6Y9-1", "protein_name": "Lymphocyte antigen 96", "gene_name": "LY96", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYK1-1", "protein_name": "Toll-like receptor 7", "gene_name": "TLR7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06187-1", "protein_name": "Tyrosine-protein kinase BTK", "gene_name": "BTK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02675-1", "protein_name": "Fibrinogen beta chain", "gene_name": "FGB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05109-1", "protein_name": "Protein S100-A8", "gene_name": "S100A8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG62-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Chicken" }, { "uniprot_canonical_ac": "P51617-1", "protein_name": "Interleukin-1 receptor-associated kinase 1", "gene_name": "IRAK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y616-1", "protein_name": "Interleukin-1 receptor-associated kinase 3", "gene_name": "IRAK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15399-1", "protein_name": "Toll-like receptor 1", "gene_name": "TLR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60602-1", "protein_name": "Toll-like receptor 5", "gene_name": "TLR5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BXR5-1", "protein_name": "Toll-like receptor 10", "gene_name": "TLR10", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y2C9-1", "protein_name": "Toll-like receptor 6", "gene_name": "TLR6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NR96-1", "protein_name": "Toll-like receptor 9", "gene_name": "TLR9", "tax_name": "Human" }, { "uniprot_canonical_ac": "A5HNF6-1", "protein_name": "Myeloid differentiation primary response protein MyD88", "gene_name": "MYD88", "tax_name": "Chicken" }, { "uniprot_canonical_ac": "E1C626-1", "protein_name": "TNF receptor-associated factor", "gene_name": "TRAF6", "tax_name": "Chicken" }, { "uniprot_canonical_ac": "P79781-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Chicken" }, { "uniprot_canonical_ac": "Q9DD78-1", "protein_name": "Toll-like receptor 2 type-1", "gene_name": "TLR2-1", "tax_name": "Chicken" }, { "uniprot_canonical_ac": "P08571-1", "protein_name": "Monocyte differentiation antigen CD14", "gene_name": "CD14", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99836-1", "protein_name": "Myeloid differentiation primary response protein MyD88", "gene_name": "MYD88", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23297-1", "protein_name": "Protein S100-A1", "gene_name": "S100A1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P02671", "url": "https://www.uniprot.org/uniprotkb/P02671" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.19224918", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 37 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", 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"count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { 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"gene_name": "TLR6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NR96-1", "protein_name": "Toll-like receptor 9", "gene_name": "TLR9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08571-1", "protein_name": "Monocyte differentiation antigen CD14", "gene_name": "CD14", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99836-1", "protein_name": "Myeloid differentiation primary response protein MyD88", "gene_name": "MYD88", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23297-1", "protein_name": "Protein S100-A1", "gene_name": "S100A1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P02671", "url": "https://www.uniprot.org/uniprotkb/P02671" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.19592493", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": 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"field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "MyD88 adapter-like (Mal)/TIRAP interaction with TRAF6 is critical for TLR2- and TLR4-mediated NF-kappaB proinflammatory responses.", "journal": "The Journal of biological chemistry", "date": "2009", "authors": "Verstak B, Nagpal K, Bottomley SP, Golenbock DT, Hertzog PJ, Mansell A", "reference": { "type": "PubMed", "id": "19592497", "url": 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Tsuchida A, Aoki T, Shimahara M, Yasunami Y, Itoi T, Moriyasu F, Negishi A, Kuwabara H, Shoji A, Hirohashi S, Yamada T", "reference": { "type": "PubMed", "id": "19696023", "url": "https://pubmed.ncbi.nlm.nih.gov/19696023" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P02671-1", "protein_name": "Fibrinogen alpha chain", "gene_name": "FGA", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P02671", "url": "https://www.uniprot.org/uniprotkb/P02671" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.19696023", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { 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"glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer.", "journal": "Nature immunology", "date": "2010", "authors": "Stewart CR, Stuart LM, Wilkinson K, van Gils JM, Deng J, Halle A, Rayner KJ, Boyer L, Zhong R, Frazier WA, Lacy-Hulbert A, El Khoury J, Golenbock DT, Moore KJ", "reference": { "type": "PubMed", "id": "20037584", "url": "https://pubmed.ncbi.nlm.nih.gov/20037584" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P02671-1", "protein_name": "Fibrinogen 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"protein_name": "Lipopolysaccharide-binding protein", "gene_name": "LBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6Y9-1", "protein_name": "Lymphocyte antigen 96", "gene_name": "LY96", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35247-1", "protein_name": "Pulmonary surfactant-associated protein D", "gene_name": "SFTPD", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49023-1", "protein_name": "Paxillin", "gene_name": "PXN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYK1-1", "protein_name": "Toll-like receptor 7", "gene_name": "TLR7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07948-1", "protein_name": "Tyrosine-protein kinase Lyn", "gene_name": "LYN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9EPW9-1", "protein_name": "Toll-like receptor 6", "gene_name": "Tlr6", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "P02675-1", "protein_name": "Fibrinogen beta chain", "gene_name": "FGB", "tax_name": "Human" }, { "uniprot_canonical_ac": 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cell surface location. Loss of oxLDL-induced NF-kappa-B activation.", "evidence": [ { "database": "UniProtKB", "id": "P16671", "url": "https://www.uniprot.org/uniprotkb/P16671" }, { "database": "PubMed", "id": "20037584", "url": "https://pubmed.ncbi.nlm.nih.gov/20037584" } ], "uniprot_canonical_ac": "P16671-1" }, { "start_pos": 463, "end_pos": 463, "sequence_org": "Y", "sequence_mut": "A", "comment": "No effect on cell surface location. Loss of oxLDL-induced NF-kappa-B activation. Loss of complex formation with TLR4 and TLR6.", "evidence": [ { "database": "UniProtKB", "id": "P16671", "url": "https://www.uniprot.org/uniprotkb/P16671" }, { "database": "PubMed", "id": "20037584", "url": "https://pubmed.ncbi.nlm.nih.gov/20037584" } ], "uniprot_canonical_ac": "P16671-1" }, { "start_pos": 464, "end_pos": 464, "sequence_org": "C", "sequence_mut": "S", "comment": "No effect on cell surface location, nor on oxLDL-induced NF-kappa-B activation.", "evidence": [ { "database": "UniProtKB", "id": "P16671", "url": "https://www.uniprot.org/uniprotkb/P16671" }, { "database": "PubMed", "id": "20037584", "url": "https://pubmed.ncbi.nlm.nih.gov/20037584" } ], "uniprot_canonical_ac": "P16671-1" } ], "record_id": "pubmed.20037584", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 29 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", 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], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The Toll-like receptor 4 ligands Mrp8 and Mrp14 are crucial in the development of autoreactive CD8+ T cells.", "journal": "Nature medicine", "date": "2010", "authors": "Loser K, Vogl T, Voskort M, Lueken A, Kupas V, Nacken W, Klenner L, Kuhn A, Foell D, Sorokin L, Luger TA, Roth J, Beissert S", "reference": { "type": "PubMed", "id": "20473308", "url": "https://pubmed.ncbi.nlm.nih.gov/20473308" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P02671-1", "protein_name": "Fibrinogen alpha chain", "gene_name": "FGA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06702-1", "protein_name": "Protein S100-A9", "gene_name": "S100A9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04114-1", "protein_name": "Apolipoprotein B-100", "gene_name": "APOB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09429-1", "protein_name": "High mobility group protein B1", "gene_name": "HMGB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02679-1", "protein_name": "Fibrinogen gamma chain", "gene_name": "FGG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IWL1-1", "protein_name": "Pulmonary surfactant-associated protein A2", "gene_name": "SFTPA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IWL2-1", "protein_name": "Pulmonary surfactant-associated protein A1", "gene_name": "SFTPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16671-1", "protein_name": "Platelet glycoprotein 4", "gene_name": "CD36", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60603-1", "protein_name": "Toll-like receptor 2", "gene_name": "TLR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57764-1", "protein_name": "Gasdermin-D", "gene_name": "GSDMD", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60443-1", "protein_name": "Gasdermin-E", "gene_name": "GSDME", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00206-1", "protein_name": "Toll-like receptor 4", "gene_name": "TLR4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P18428-1", "protein_name": "Lipopolysaccharide-binding protein", "gene_name": "LBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6Y9-1", "protein_name": "Lymphocyte antigen 96", "gene_name": "LY96", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35247-1", "protein_name": "Pulmonary surfactant-associated protein D", "gene_name": "SFTPD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYK1-1", "protein_name": "Toll-like receptor 7", "gene_name": "TLR7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02675-1", "protein_name": "Fibrinogen beta chain", "gene_name": "FGB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05109-1", "protein_name": "Protein S100-A8", "gene_name": "S100A8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15399-1", "protein_name": "Toll-like receptor 1", "gene_name": "TLR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y2C9-1", "protein_name": "Toll-like receptor 6", "gene_name": "TLR6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08571-1", "protein_name": "Monocyte differentiation antigen CD14", "gene_name": "CD14", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23297-1", "protein_name": "Protein S100-A1", "gene_name": "S100A1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P02671", "url": "https://www.uniprot.org/uniprotkb/P02671" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.20473308", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 22 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Helical assembly in the MyD88-IRAK4-IRAK2 complex in TLR/IL-1R signalling.", "journal": "Nature", "date": "2010", "authors": "Lin SC, Lo YC, Wu H", "reference": { "type": "PubMed", "id": "20485341", "url": "https://pubmed.ncbi.nlm.nih.gov/20485341" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P02671-1", "protein_name": "Fibrinogen alpha chain", "gene_name": "FGA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06702-1", "protein_name": "Protein S100-A9", "gene_name": "S100A9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13233-1", "protein_name": "Mitogen-activated protein kinase kinase kinase 1", "gene_name": "MAP3K1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43187-1", "protein_name": "Interleukin-1 receptor-associated kinase-like 2", "gene_name": "IRAK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P58753-1", "protein_name": "Toll/interleukin-1 receptor domain-containing adapter protein", "gene_name": "TIRAP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y4K3-1", "protein_name": "TNF receptor-associated factor 6", "gene_name": "TRAF6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09429-1", "protein_name": "High mobility group protein B1", "gene_name": "HMGB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15524-1", "protein_name": "Suppressor of cytokine signaling 1", "gene_name": "SOCS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02679-1", "protein_name": "Fibrinogen gamma chain", "gene_name": "FGG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NWZ3-1", "protein_name": "Interleukin-1 receptor-associated kinase 4", "gene_name": "IRAK4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6IA17-1", "protein_name": "Single Ig IL-1-related receptor", "gene_name": "SIGIRR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BQ95-1", "protein_name": "Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial", "gene_name": "ECSIT", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16671-1", "protein_name": "Platelet glycoprotein 4", "gene_name": "CD36", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60603-1", "protein_name": "Toll-like receptor 2", "gene_name": "TLR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00206-1", "protein_name": "Toll-like receptor 4", "gene_name": "TLR4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6Y9-1", "protein_name": "Lymphocyte antigen 96", "gene_name": "LY96", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYK1-1", "protein_name": "Toll-like receptor 7", "gene_name": "TLR7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06187-1", "protein_name": "Tyrosine-protein kinase BTK", "gene_name": "BTK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02675-1", "protein_name": "Fibrinogen beta chain", "gene_name": "FGB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05109-1", "protein_name": "Protein S100-A8", "gene_name": "S100A8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51617-1", "protein_name": "Interleukin-1 receptor-associated kinase 1", "gene_name": "IRAK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y616-1", "protein_name": "Interleukin-1 receptor-associated kinase 3", "gene_name": "IRAK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15399-1", "protein_name": "Toll-like receptor 1", "gene_name": "TLR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60602-1", "protein_name": "Toll-like receptor 5", "gene_name": "TLR5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BXR5-1", "protein_name": "Toll-like receptor 10", "gene_name": "TLR10", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y2C9-1", "protein_name": "Toll-like receptor 6", "gene_name": "TLR6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NR96-1", "protein_name": "Toll-like receptor 9", "gene_name": "TLR9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08571-1", "protein_name": "Monocyte differentiation antigen CD14", "gene_name": "CD14", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99836-1", "protein_name": "Myeloid differentiation primary response protein MyD88", "gene_name": "MYD88", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23297-1", "protein_name": "Protein S100-A1", "gene_name": "S100A1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P02671", "url": "https://www.uniprot.org/uniprotkb/P02671" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.20485341", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 30 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Fibrinogen Kyoto II, a new congenitally abnormal molecule, characterized by the replacement of A alpha proline-18 by leucine.", "journal": "Blood", "date": "1991", "authors": "Yoshida N, Okuma M, Hirata H, Matsuda M, Yamazumi K, Asakura S", "reference": { "type": "PubMed", "id": "2070049", "url": "https://pubmed.ncbi.nlm.nih.gov/2070049" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P02671-1", "protein_name": "Fibrinogen alpha chain", "gene_name": "FGA", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P02671", "url": "https://www.uniprot.org/uniprotkb/P02671" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.2070049", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Two human MYD88 variants, S34Y and R98C, interfere with MyD88-IRAK4-myddosome assembly.", "journal": "The Journal of biological chemistry", "date": "2011", "authors": "George J, Motshwene PG, Wang H, Kubarenko AV, Rautanen A, Mills TC, Hill AV, Gay NJ, Weber AN", "reference": { "type": "PubMed", "id": "20966070", "url": "https://pubmed.ncbi.nlm.nih.gov/20966070" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P02671-1", "protein_name": "Fibrinogen alpha chain", "gene_name": "FGA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06702-1", "protein_name": "Protein S100-A9", "gene_name": "S100A9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13233-1", "protein_name": "Mitogen-activated protein kinase kinase kinase 1", "gene_name": "MAP3K1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43187-1", "protein_name": "Interleukin-1 receptor-associated kinase-like 2", "gene_name": "IRAK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P58753-1", "protein_name": "Toll/interleukin-1 receptor domain-containing adapter protein", "gene_name": "TIRAP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y4K3-1", "protein_name": "TNF receptor-associated factor 6", "gene_name": "TRAF6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09429-1", "protein_name": "High mobility group protein B1", "gene_name": "HMGB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15524-1", "protein_name": "Suppressor of cytokine signaling 1", "gene_name": "SOCS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02679-1", "protein_name": "Fibrinogen gamma chain", "gene_name": "FGG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NWZ3-1", "protein_name": "Interleukin-1 receptor-associated kinase 4", "gene_name": "IRAK4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6IA17-1", "protein_name": "Single Ig IL-1-related receptor", "gene_name": "SIGIRR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BQ95-1", "protein_name": "Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial", "gene_name": "ECSIT", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16671-1", "protein_name": "Platelet glycoprotein 4", "gene_name": "CD36", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60603-1", "protein_name": "Toll-like receptor 2", "gene_name": "TLR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00206-1", "protein_name": "Toll-like receptor 4", "gene_name": "TLR4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6Y9-1", "protein_name": "Lymphocyte antigen 96", "gene_name": "LY96", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYK1-1", "protein_name": "Toll-like receptor 7", "gene_name": "TLR7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06187-1", "protein_name": "Tyrosine-protein kinase BTK", "gene_name": "BTK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02675-1", "protein_name": "Fibrinogen beta chain", "gene_name": "FGB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05109-1", "protein_name": "Protein S100-A8", "gene_name": "S100A8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51617-1", "protein_name": "Interleukin-1 receptor-associated kinase 1", "gene_name": "IRAK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y616-1", "protein_name": "Interleukin-1 receptor-associated kinase 3", "gene_name": "IRAK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15399-1", "protein_name": "Toll-like receptor 1", "gene_name": "TLR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60602-1", "protein_name": "Toll-like receptor 5", "gene_name": "TLR5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y2C9-1", "protein_name": "Toll-like receptor 6", "gene_name": "TLR6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NR96-1", "protein_name": "Toll-like receptor 9", "gene_name": "TLR9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08571-1", "protein_name": "Monocyte differentiation antigen CD14", "gene_name": "CD14", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99836-1", "protein_name": "Myeloid differentiation primary response protein MyD88", "gene_name": "MYD88", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23297-1", "protein_name": "Protein S100-A1", "gene_name": "S100A1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P02671", "url": "https://www.uniprot.org/uniprotkb/P02671" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.20966070", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 29 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Nucleotide sequences of the three genes coding for human fibrinogen.", "journal": "Adv. Exp. Med. Biol.", "date": "1990", "authors": "Chung D W, Harris J E, Davie E W", "reference": { "type": "PubMed", "id": "2102623", "url": "https://pubmed.ncbi.nlm.nih.gov/2102623" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P02671-1", "protein_name": "Fibrinogen alpha chain", "gene_name": "FGA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02675-1", "protein_name": "Fibrinogen beta chain", "gene_name": "FGB", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P02671", "url": "https://www.uniprot.org/uniprotkb/P02671" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.2102623", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ 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"glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Human interleukin-1 receptor-associated kinase-2 is essential for Toll-like receptor-mediated transcriptional and post-transcriptional regulation of tumor necrosis factor alpha.", "journal": "The Journal of biological chemistry", "date": "2011", "authors": "Flannery SM, Keating SE, Szymak J, Bowie AG", "reference": { "type": "PubMed", "id": "21606490", "url": "https://pubmed.ncbi.nlm.nih.gov/21606490" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P02671-1", "protein_name": "Fibrinogen alpha chain", "gene_name": "FGA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06702-1", "protein_name": "Protein S100-A9", "gene_name": "S100A9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13233-1", "protein_name": "Mitogen-activated protein kinase kinase kinase 1", "gene_name": "MAP3K1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43187-1", "protein_name": "Interleukin-1 receptor-associated kinase-like 2", "gene_name": "IRAK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P58753-1", "protein_name": "Toll/interleukin-1 receptor domain-containing adapter protein", "gene_name": "TIRAP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y4K3-1", "protein_name": "TNF receptor-associated factor 6", "gene_name": "TRAF6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09429-1", "protein_name": "High mobility group protein B1", "gene_name": "HMGB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15524-1", "protein_name": "Suppressor of cytokine signaling 1", "gene_name": "SOCS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02679-1", "protein_name": "Fibrinogen gamma chain", "gene_name": "FGG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NWZ3-1", "protein_name": "Interleukin-1 receptor-associated kinase 4", "gene_name": "IRAK4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6IA17-1", "protein_name": "Single Ig IL-1-related receptor", "gene_name": "SIGIRR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BQ95-1", "protein_name": "Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial", "gene_name": "ECSIT", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16671-1", "protein_name": "Platelet glycoprotein 4", "gene_name": "CD36", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60603-1", "protein_name": "Toll-like receptor 2", "gene_name": "TLR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00206-1", "protein_name": "Toll-like receptor 4", "gene_name": "TLR4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6Y9-1", "protein_name": "Lymphocyte antigen 96", "gene_name": "LY96", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06187-1", "protein_name": "Tyrosine-protein kinase BTK", "gene_name": "BTK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02675-1", "protein_name": "Fibrinogen beta chain", "gene_name": "FGB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05109-1", "protein_name": "Protein S100-A8", "gene_name": "S100A8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51617-1", "protein_name": "Interleukin-1 receptor-associated kinase 1", "gene_name": "IRAK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y616-1", "protein_name": "Interleukin-1 receptor-associated kinase 3", "gene_name": "IRAK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15399-1", "protein_name": "Toll-like receptor 1", "gene_name": "TLR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y2C9-1", "protein_name": "Toll-like receptor 6", "gene_name": "TLR6", 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"protein_name": "Fibrinogen alpha chain", "gene_name": "FGA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06702-1", "protein_name": "Protein S100-A9", "gene_name": "S100A9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04114-1", "protein_name": "Apolipoprotein B-100", "gene_name": "APOB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09429-1", "protein_name": "High mobility group protein B1", "gene_name": "HMGB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02679-1", "protein_name": "Fibrinogen gamma chain", "gene_name": "FGG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IWL1-1", "protein_name": "Pulmonary surfactant-associated protein A2", "gene_name": "SFTPA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IWL2-1", "protein_name": "Pulmonary surfactant-associated protein A1", "gene_name": "SFTPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16671-1", "protein_name": "Platelet glycoprotein 4", "gene_name": "CD36", "tax_name": "Human" }, { 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[] } ] }, { "title": "Bruton's tyrosine kinase phosphorylates Toll-like receptor 3 to initiate antiviral response.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2012", "authors": "Lee KG, Xu S, Kang ZH, Huo J, Huang M, Liu D, Takeuchi O, Akira S, Lam KP", "reference": { "type": "PubMed", "id": "22454496", "url": "https://pubmed.ncbi.nlm.nih.gov/22454496" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P02671-1", "protein_name": "Fibrinogen alpha chain", "gene_name": "FGA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06702-1", "protein_name": "Protein S100-A9", "gene_name": "S100A9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13233-1", "protein_name": "Mitogen-activated protein kinase kinase kinase 1", "gene_name": "MAP3K1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43187-1", "protein_name": "Interleukin-1 receptor-associated kinase-like 2", "gene_name": "IRAK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P58753-1", "protein_name": "Toll/interleukin-1 receptor domain-containing adapter protein", "gene_name": "TIRAP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y4K3-1", "protein_name": "TNF receptor-associated factor 6", "gene_name": "TRAF6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09429-1", "protein_name": "High mobility group protein B1", "gene_name": "HMGB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15524-1", "protein_name": "Suppressor of cytokine signaling 1", "gene_name": "SOCS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02679-1", "protein_name": "Fibrinogen gamma chain", "gene_name": "FGG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NWZ3-1", "protein_name": "Interleukin-1 receptor-associated kinase 4", "gene_name": "IRAK4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6IA17-1", "protein_name": "Single Ig IL-1-related receptor", "gene_name": "SIGIRR", "tax_name": "Human" }, { 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"count": 0 } ], "sort_fields": [] } ] }, { "title": "Pro-inflammatory S100A8 and S100A9 proteins: self-assembly into multifunctional native and amyloid complexes.", "journal": "International journal of molecular sciences", "date": "2012", "authors": "Vogl T, Gharibyan AL, Morozova-Roche LA", "reference": { "type": "PubMed", "id": "22489132", "url": "https://pubmed.ncbi.nlm.nih.gov/22489132" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P02671-1", "protein_name": "Fibrinogen alpha chain", "gene_name": "FGA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06702-1", "protein_name": "Protein S100-A9", "gene_name": "S100A9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04114-1", "protein_name": "Apolipoprotein B-100", "gene_name": "APOB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09429-1", "protein_name": "High mobility group protein B1", "gene_name": "HMGB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02679-1", "protein_name": 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[] } ] }, { "title": "Functional assessment of the mutational effects of human IRAK4 and MyD88 genes.", "journal": "Molecular immunology", "date": "2014", "authors": "Yamamoto T, Tsutsumi N, Tochio H, Ohnishi H, Kubota K, Kato Z, Shirakawa M, Kondo N", "reference": { "type": "PubMed", "id": "24316379", "url": "https://pubmed.ncbi.nlm.nih.gov/24316379" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P02671-1", "protein_name": "Fibrinogen alpha chain", "gene_name": "FGA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06702-1", "protein_name": "Protein S100-A9", "gene_name": "S100A9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P58753-1", "protein_name": "Toll/interleukin-1 receptor domain-containing adapter protein", "gene_name": "TIRAP", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09429-1", "protein_name": "High mobility group protein B1", "gene_name": "HMGB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02679-1", "protein_name": 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"count": 0 } ], "sort_fields": [] } ] }, { "title": "Phagocytosis escape by a Staphylococcus aureus protein that connects complement and coagulation proteins at the bacterial surface.", "journal": "PLoS Pathog.", "date": "2013", "authors": "Ko Ya-Ping, Kuipers Annemarie, Freitag Claudia M, Jongerius Ilse, Medina Eva, van Rooijen Willemien J, Spaan Andr\u00e1s N, van Kessel Kok P M, H\u00f6\u00f6k Magnus, Rooijakkers Suzan H M", "reference": { "type": "PubMed", "id": "24348255", "url": "https://pubmed.ncbi.nlm.nih.gov/24348255" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P02671-1", "protein_name": "Fibrinogen alpha chain", "gene_name": "FGA", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P02671", "url": "https://www.uniprot.org/uniprotkb/P02671" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": 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Kubatzky KF, Volkers M, Herzog N, Mahler M, Tsoporis JN, Parker TG, Linke B, Giannitsis E, Gao E, Peppel K, Katus HA, Most P", "reference": { "type": "PubMed", "id": "24833748", "url": "https://pubmed.ncbi.nlm.nih.gov/24833748" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P02671-1", "protein_name": "Fibrinogen alpha chain", "gene_name": "FGA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06702-1", "protein_name": "Protein S100-A9", "gene_name": "S100A9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04114-1", "protein_name": "Apolipoprotein B-100", "gene_name": "APOB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09429-1", "protein_name": "High mobility group protein B1", "gene_name": "HMGB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02679-1", "protein_name": "Fibrinogen gamma chain", "gene_name": "FGG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IWL1-1", "protein_name": "Pulmonary surfactant-associated protein 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"tax_name": "Human" }, { "uniprot_canonical_ac": "P02675-1", "protein_name": "Fibrinogen beta chain", "gene_name": "FGB", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P02671", "url": "https://www.uniprot.org/uniprotkb/P02671" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.25427968", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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[] } ] }, { "title": "Structural Analysis Reveals that Toll-like Receptor 7 Is a Dual Receptor for Guanosine and Single-Stranded RNA.", "journal": "Immunity", "date": "2016-10-18", "authors": "Zhang Zhikuan, Ohto Umeharu, Shibata Takuma, Krayukhina Elena, Taoka Masato, Yamauchi Yoshio, Tanji Hiromi, Isobe Toshiaki, Uchiyama Susumu, Miyake Kensuke, Shimizu Toshiyuki", "reference": { "type": "PubMed", "id": "27742543", "url": "https://pubmed.ncbi.nlm.nih.gov/27742543" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P02671-1", "protein_name": "Fibrinogen alpha chain", "gene_name": "FGA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06702-1", "protein_name": "Protein S100-A9", "gene_name": "S100A9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04114-1", "protein_name": "Apolipoprotein B-100", "gene_name": "APOB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09429-1", "protein_name": "High mobility group protein B1", "gene_name": "HMGB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02679-1", "protein_name": "Fibrinogen gamma chain", "gene_name": "FGG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IWL1-1", "protein_name": "Pulmonary surfactant-associated protein A2", "gene_name": "SFTPA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IWL2-1", "protein_name": "Pulmonary surfactant-associated protein A1", "gene_name": "SFTPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16671-1", "protein_name": "Platelet glycoprotein 4", "gene_name": "CD36", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60603-1", "protein_name": "Toll-like receptor 2", "gene_name": "TLR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57764-1", "protein_name": "Gasdermin-D", "gene_name": "GSDMD", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60443-1", "protein_name": "Gasdermin-E", "gene_name": "GSDME", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00206-1", "protein_name": "Toll-like receptor 4", 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Biol. Chem.", "date": "1986", "authors": "Kimura S, Aoki N", "reference": { "type": "PubMed", "id": "2877981", "url": "https://pubmed.ncbi.nlm.nih.gov/2877981" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P02671-1", "protein_name": "Fibrinogen alpha chain", "gene_name": "FGA", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P02671", "url": "https://www.uniprot.org/uniprotkb/P02671" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.2877981", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", 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"P06702-1", "protein_name": "Protein S100-A9", "gene_name": "S100A9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P58753-1", "protein_name": "Toll/interleukin-1 receptor domain-containing adapter protein", "gene_name": "TIRAP", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09429-1", "protein_name": "High mobility group protein B1", "gene_name": "HMGB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02679-1", "protein_name": "Fibrinogen gamma chain", "gene_name": "FGG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NWZ3-1", "protein_name": "Interleukin-1 receptor-associated kinase 4", "gene_name": "IRAK4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16671-1", "protein_name": "Platelet glycoprotein 4", "gene_name": "CD36", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60603-1", "protein_name": "Toll-like receptor 2", "gene_name": "TLR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00206-1", "protein_name": "Toll-like receptor 4", "gene_name": 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