[ { "title": "Allosteric Activation of Ubiquitin-Specific Proteases by beta-Propeller Proteins UAF1 and WDR20.", "journal": "Molecular cell", "date": "2016", "authors": "Li H, Lim KS, Kim H, Hinds TR, Jo U, Mao H, Weller CE, Sun J, Chatterjee C, D'Andrea AD, Zheng N", "reference": { "type": "PubMed", "id": "27373336", "url": "https://pubmed.ncbi.nlm.nih.gov/27373336" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O75317-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 12", "gene_name": "USP12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TBZ3-1", "protein_name": "WD repeat-containing protein 20", "gene_name": "WDR20", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TAF3-1", "protein_name": "WD repeat-containing protein 48", "gene_name": "WDR48", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O75317", "url": "https://www.uniprot.org/uniprotkb/O75317" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 208, "end_pos": 210, "sequence_org": "QNT", "sequence_mut": "GGG", "comment": "Loss of activity.", "evidence": [ { "database": "UniProtKB", "id": "O75317", "url": "https://www.uniprot.org/uniprotkb/O75317" }, { "database": "PubMed", "id": "27373336", "url": "https://pubmed.ncbi.nlm.nih.gov/27373336" } ], "uniprot_canonical_ac": "O75317-1" }, { "start_pos": 219, "end_pos": 219, "sequence_org": "F", "sequence_mut": "A", "comment": "Loss of activity.", "evidence": [ { "database": "UniProtKB", "id": "O75317", "url": "https://www.uniprot.org/uniprotkb/O75317" }, { "database": "PubMed", "id": "27373336", "url": "https://pubmed.ncbi.nlm.nih.gov/27373336" } ], "uniprot_canonical_ac": "O75317-1" }, { "start_pos": 240, "end_pos": 240, "sequence_org": "Q", "sequence_mut": "A", "comment": "Impaired binding to WDR48; when associated with A-241.", "evidence": [ { "database": "UniProtKB", "id": "O75317", "url": "https://www.uniprot.org/uniprotkb/O75317" }, { "database": "PubMed", "id": "27373336", "url": "https://pubmed.ncbi.nlm.nih.gov/27373336" } ], "uniprot_canonical_ac": "O75317-1" }, { "start_pos": 241, "end_pos": 241, "sequence_org": "E", "sequence_mut": "A", "comment": "Impaired binding to WDR48; when associated with A-240.", "evidence": [ { "database": "UniProtKB", "id": "O75317", "url": "https://www.uniprot.org/uniprotkb/O75317" }, { "database": "PubMed", "id": "27373336", "url": "https://pubmed.ncbi.nlm.nih.gov/27373336" } ], "uniprot_canonical_ac": "O75317-1" }, { "start_pos": 264, "end_pos": 264, "sequence_org": "Y", "sequence_mut": "A", "comment": "Strong reduction of activity.", "evidence": [ { "database": "UniProtKB", "id": "O75317", "url": "https://www.uniprot.org/uniprotkb/O75317" }, { "database": "PubMed", "id": "27373336", "url": "https://pubmed.ncbi.nlm.nih.gov/27373336" } ], "uniprot_canonical_ac": "O75317-1" }, { "start_pos": 279, "end_pos": 279, "sequence_org": "V", "sequence_mut": "D", "comment": "Impaired binding to WDR20; when associated with A-287. 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Med.", "date": "2009", "authors": "Luddi A, Margollicci M, Gambera L, Serafini F, Cioni M, De Leo V, Balestri P, Piomboni P", "reference": { "type": "PubMed", "id": "19246359", "url": "https://pubmed.ncbi.nlm.nih.gov/19246359" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O00507-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 9Y", "gene_name": "USP9Y", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O00507", "url": "https://www.uniprot.org/uniprotkb/O00507" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.19246359", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", 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"date": "2008", "authors": "Morstadt Lucia, Bohm Andrew, Y\u00fcksel Deniz, Kumar Krishna, Stollar B David, Baleja James D", "reference": { "type": "PubMed", "id": "18287279", "url": "https://pubmed.ncbi.nlm.nih.gov/18287279" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P12018-1", "protein_name": "Immunoglobulin iota chain", "gene_name": "VPREB1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P12018", "url": "https://www.uniprot.org/uniprotkb/P12018" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.18287279", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", 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Dial. 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"authors": "Massimo G, Khambata R S, Chapman T, Birchall K, Raimondi C, Shabbir A, Dyson Nicki, Rathod K S, Borghi C, Ahluwalia A", "reference": { "type": "PubMed", "id": "37713777", "url": "https://pubmed.ncbi.nlm.nih.gov/37713777" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P47989-1", "protein_name": "Xanthine dehydrogenase/oxidase", "gene_name": "XDH", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P47989", "url": "https://www.uniprot.org/uniprotkb/P47989" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.37713777", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", 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"count": 0 } ], "sort_fields": [] } ] }, { "title": "Increased Serum VEGF-B Level Is Associated With Renal Function Impairment in Patients With Type 2 Diabetes.", "journal": "Frontiers in endocrinology", "date": "2022", "authors": "Wei Y, Han S, Zhou R, Xu P, Zhou L, Zhu Z, Kan Y, Yang X, Xiang Y, Cao Y, Jin Y, Yan J, Yu X, Wang X, Shang W", "reference": { "type": "PubMed", "id": "35399943", "url": "https://pubmed.ncbi.nlm.nih.gov/35399943" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P49765-1", "protein_name": "Vascular endothelial growth factor B", "gene_name": "VEGFB", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P49765", "url": "https://www.uniprot.org/uniprotkb/P49765" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.35399943", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], 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