[ { "title": "Structures of human folate receptors reveal biological trafficking states and diversity in folate and antifolate recognition.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2013", "authors": "Wibowo AS, Singh M, Reeder KM, Carter JJ, Kovach AR, Meng W, Ratnam M, Zhang F, Dann CE 3rd", "reference": { "type": "PubMed", "id": "23934049", "url": "https://pubmed.ncbi.nlm.nih.gov/23934049" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P34897-1", "protein_name": "Serine hydroxymethyltransferase, mitochondrial", "gene_name": "SHMT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q3SY69-1", "protein_name": "Mitochondrial 10-formyltetrahydrofolate dehydrogenase", "gene_name": "ALDH1L2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H903-4", "protein_name": "Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, mitochondrial", "gene_name": "MTHFD2L", "tax_name": 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"uniprot_canonical_ac": "Q9H903-4", "protein_name": "Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, mitochondrial", "gene_name": "MTHFD2L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96NT5-1", "protein_name": "Proton-coupled folate transporter", "gene_name": "SLC46A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41440-1", "protein_name": "Reduced folate transporter", "gene_name": "SLC19A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P34896-1", "protein_name": "Serine hydroxymethyltransferase, cytosolic", "gene_name": "SHMT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75891-1", "protein_name": "Cytosolic 10-formyltetrahydrofolate dehydrogenase", "gene_name": "ALDH1L1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14207-1", "protein_name": "Folate receptor beta", "gene_name": "FOLR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UB35-1", "protein_name": "Monofunctional C1-tetrahydrofolate synthase, mitochondrial", "gene_name": "MTHFD1L", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11586-1", "protein_name": "C-1-tetrahydrofolate synthase, cytoplasmic", "gene_name": "MTHFD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00374-1", "protein_name": "Dihydrofolate reductase", "gene_name": "DHFR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42898-1", "protein_name": "Methylenetetrahydrofolate reductase (NADPH)", "gene_name": "MTHFR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49914-1", "protein_name": "5-formyltetrahydrofolate cyclo-ligase", "gene_name": "MTHFS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P13995-1", "protein_name": "Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial", "gene_name": "MTHFD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "D3YZG8-1", "protein_name": "Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, mitochondrial", "gene_name": "Mthfd2l", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q86XF0-1", "protein_name": "Dihydrofolate reductase 2, mitochondrial", "gene_name": "DHFR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H2D1-1", "protein_name": "Solute carrier family 25 member 32", "gene_name": "SLC25A32", "tax_name": "Human" }, { "uniprot_canonical_ac": "D3ZUA0-1", "protein_name": "Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, mitochondrial", "gene_name": "Mthfd2l", "tax_name": "Rat" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P34897", "url": "https://www.uniprot.org/uniprotkb/P34897" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.24733394", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 18 } ], "sort_fields": [ 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Autism and intellectual disability-associated KIRREL3 interacts with neuronal proteins MAP1B and MYO16 with potential roles in neurodevelopment.", "journal": "PLoS ONE", "date": "2015", "authors": "Liu YF, Sowell SM, Luo Y, Chaubey A, Cameron RS, Kim HG, Srivastava AK", "reference": { "type": "PubMed", "id": "25902260", "url": "https://pubmed.ncbi.nlm.nih.gov/25902260" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P34897-1", "protein_name": "Serine hydroxymethyltransferase, mitochondrial", "gene_name": "SHMT2", "tax_name": "Human" }, { 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"n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Homologous membrane folate binding proteins in human placenta: cloning and sequence of a cDNA.", "journal": "Biochemistry", "date": "1989", "authors": "Ratnam M, Marquardt H, Duhring JL, Freisheim JH", "reference": { "type": "PubMed", "id": 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"tax_name": "Human" }, { "uniprot_canonical_ac": "P13995-1", "protein_name": "Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial", "gene_name": "MTHFD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86XF0-1", "protein_name": "Dihydrofolate reductase 2, mitochondrial", "gene_name": "DHFR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H2D1-1", "protein_name": "Solute carrier family 25 member 32", "gene_name": "SLC25A32", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P34897", "url": "https://www.uniprot.org/uniprotkb/P34897" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.2605182", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 16 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"journal": "International journal of molecular sciences", "date": "2020", "authors": "Kozminski P, Halik PK, Chesori R, Gniazdowska E", "reference": { "type": "PubMed", "id": "32423175", "url": "https://pubmed.ncbi.nlm.nih.gov/32423175" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P34897-1", "protein_name": "Serine hydroxymethyltransferase, mitochondrial", "gene_name": "SHMT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q3SY69-1", "protein_name": "Mitochondrial 10-formyltetrahydrofolate dehydrogenase", "gene_name": "ALDH1L2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H903-4", "protein_name": "Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, mitochondrial", "gene_name": "MTHFD2L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96NT5-1", "protein_name": "Proton-coupled folate transporter", "gene_name": "SLC46A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41440-1", "protein_name": "Reduced folate 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"protein_name": "C-1-tetrahydrofolate synthase, cytoplasmic", "gene_name": "MTHFD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00374-1", "protein_name": "Dihydrofolate reductase", "gene_name": "DHFR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42898-1", "protein_name": "Methylenetetrahydrofolate reductase (NADPH)", "gene_name": "MTHFR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49914-1", "protein_name": "5-formyltetrahydrofolate cyclo-ligase", "gene_name": "MTHFS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P13995-1", "protein_name": "Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial", "gene_name": "MTHFD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86XF0-1", "protein_name": "Dihydrofolate reductase 2, mitochondrial", "gene_name": "DHFR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H2D1-1", "protein_name": "Solute carrier family 25 member 32", "gene_name": "SLC25A32", "tax_name": "Human" } ], "species": 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"count": 0 } ], "sort_fields": [] } ] }, { "title": "Cloning of human cDNAs encoding mitochondrial and cytosolic serine hydroxymethyltransferases and chromosomal localization.", "journal": "J. Biol. Chem.", "date": "1993", "authors": "Garrow T A, Brenner A A, Whitehead V M, Chen X N, Duncan R G, Korenberg J R, Shane B", "reference": { "type": "PubMed", "id": "8505317", "url": "https://pubmed.ncbi.nlm.nih.gov/8505317" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P34897-1", "protein_name": "Serine hydroxymethyltransferase, mitochondrial", "gene_name": "SHMT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P34896-1", "protein_name": "Serine hydroxymethyltransferase, cytosolic", "gene_name": "SHMT1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P34897", "url": "https://www.uniprot.org/uniprotkb/P34897" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.8505317", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { 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"field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Cloning and characterization of the human 5,10-methenyltetrahydrofolate synthetase-encoding cDNA.", "journal": "Gene", "date": "1995", "authors": "Dayan A, Bertrand R, Beauchemin M, Chahla D, Mamo A, Filion M, Skup D, Massie B, Jolivet J", "reference": { "type": "PubMed", "id": "8522195", "url": "https://pubmed.ncbi.nlm.nih.gov/8522195" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P34897-1", "protein_name": "Serine hydroxymethyltransferase, mitochondrial", "gene_name": "SHMT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q3SY69-1", "protein_name": "Mitochondrial 10-formyltetrahydrofolate dehydrogenase", "gene_name": "ALDH1L2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H903-4", "protein_name": "Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, mitochondrial", "gene_name": "MTHFD2L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96NT5-1", "protein_name": "Proton-coupled folate transporter", "gene_name": "SLC46A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41440-1", "protein_name": "Reduced folate transporter", "gene_name": "SLC19A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P34896-1", "protein_name": "Serine hydroxymethyltransferase, cytosolic", "gene_name": "SHMT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75891-1", "protein_name": "Cytosolic 10-formyltetrahydrofolate dehydrogenase", "gene_name": "ALDH1L1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14207-1", "protein_name": "Folate receptor beta", "gene_name": "FOLR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UB35-1", "protein_name": "Monofunctional C1-tetrahydrofolate synthase, mitochondrial", "gene_name": "MTHFD1L", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11586-1", "protein_name": "C-1-tetrahydrofolate synthase, cytoplasmic", "gene_name": "MTHFD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00374-1", "protein_name": "Dihydrofolate reductase", "gene_name": "DHFR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42898-1", "protein_name": "Methylenetetrahydrofolate reductase (NADPH)", "gene_name": "MTHFR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49914-1", "protein_name": "5-formyltetrahydrofolate cyclo-ligase", "gene_name": "MTHFS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P13995-1", "protein_name": "Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial", "gene_name": "MTHFD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86XF0-1", "protein_name": "Dihydrofolate reductase 2, mitochondrial", "gene_name": "DHFR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H2D1-1", "protein_name": "Solute carrier family 25 member 32", "gene_name": "SLC25A32", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P34897", "url": "https://www.uniprot.org/uniprotkb/P34897" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.8522195", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 16 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { 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"protein_name": "Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial", "gene_name": "MTHFD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86XF0-1", "protein_name": "Dihydrofolate reductase 2, mitochondrial", "gene_name": "DHFR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H2D1-1", "protein_name": "Solute carrier family 25 member 32", "gene_name": "SLC25A32", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P34897", "url": "https://www.uniprot.org/uniprotkb/P34897" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.8662720", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 17 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", 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Biol. 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Biol. Chem.", "date": "2002", "authors": "Yukitake H, Furusawa M, Taira T, Iguchi-Ariga SM, Ariga H", "reference": { "type": "PubMed", "id": "12223483", "url": "https://pubmed.ncbi.nlm.nih.gov/12223483" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q92667-1", "protein_name": "A-kinase anchor protein 1, mitochondrial", "gene_name": "AKAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99417-1", "protein_name": "c-Myc-binding protein", "gene_name": "MYCBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z4T9-7", "protein_name": "Cilia- and flagella-associated protein 91", "gene_name": "CFAP91", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8BRC6-2", "protein_name": "Cilia- and flagella-associated protein 91", "gene_name": "Cfap91", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q9EQS3-1", "protein_name": "c-Myc-binding protein", "gene_name": "Mycbp", "tax_name": "Mouse" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": 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Silverman WF, Hershfinkel M, Caporale T, Sensi SL, Parnis J, Nolte C, Fishman D, Shoshan-Barmatz V, Herrmann S, Khananshvili D, Sekler I", "reference": { "type": "PubMed", "id": "20018762", "url": "https://pubmed.ncbi.nlm.nih.gov/20018762" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q92667-1", "protein_name": "A-kinase anchor protein 1, mitochondrial", "gene_name": "AKAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6AXS0-1", "protein_name": "Mitochondrial sodium/calcium exchanger protein", "gene_name": "Slc8b1", "tax_name": "Rat" }, { "uniprot_canonical_ac": "O95202-1", "protein_name": "Mitochondrial proton/calcium exchanger protein", "gene_name": "LETM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BPX6-1", "protein_name": "Calcium uptake protein 1, mitochondrial", "gene_name": "MICU1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NE86-1", "protein_name": "Calcium uniporter protein, mitochondrial", "gene_name": "MCU", 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"o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "MICU1 and MICU2 play nonredundant roles in the regulation of the mitochondrial calcium uniporter.", "journal": "EMBO reports", "date": "2014", "authors": "Kamer KJ, Mootha VK", "reference": { "type": "PubMed", "id": "24503055", "url": "https://pubmed.ncbi.nlm.nih.gov/24503055" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q92667-1", "protein_name": "A-kinase anchor protein 1, mitochondrial", "gene_name": "AKAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95202-1", "protein_name": "Mitochondrial proton/calcium exchanger protein", "gene_name": "LETM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BPX6-1", "protein_name": "Calcium uptake protein 1, mitochondrial", "gene_name": "MICU1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NE86-1", "protein_name": "Calcium uniporter protein, mitochondrial", "gene_name": "MCU", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NWR8-1", "protein_name": "Calcium uniporter regulatory subunit MCUb, mitochondrial", "gene_name": "MCUB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P45880-3", "protein_name": "Non-selective voltage-gated ion channel VDAC2", "gene_name": "VDAC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P21796-1", "protein_name": "Non-selective voltage-gated ion channel VDAC1", "gene_name": "VDAC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86XE3-1", "protein_name": "Calcium uptake protein 3, mitochondrial", "gene_name": "MICU3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H4I9-1", "protein_name": "Essential MCU regulator, mitochondrial", "gene_name": "SMDT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6J4K2-1", "protein_name": "Mitochondrial sodium/calcium exchanger protein", "gene_name": "SLC8B1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y277-1", "protein_name": "Non-selective voltage-gated ion channel VDAC3", "gene_name": "VDAC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IYU8-1", "protein_name": "Calcium uptake protein 2, mitochondrial", "gene_name": "MICU2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57103-1", "protein_name": "Sodium/calcium exchanger 3", "gene_name": "SLC8A3", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q92667", "url": "https://www.uniprot.org/uniprotkb/Q92667" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 231, "end_pos": 231, "sequence_org": "D", "sequence_mut": "A", "comment": "Abolishes mitochondrial Ca(2+) uptake; when associated with A-242; A-421 and A-432.", "evidence": [ { "database": "UniProtKB", "id": "Q9BPX6", "url": "https://www.uniprot.org/uniprotkb/Q9BPX6" }, { "database": "PubMed", "id": "24503055", "url": "https://pubmed.ncbi.nlm.nih.gov/24503055" }, { "database": "PubMed", "id": "23101630", "url": "https://pubmed.ncbi.nlm.nih.gov/23101630" }, { "database": "PubMed", "id": "20693986", "url": 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"https://pubmed.ncbi.nlm.nih.gov/37036971" } ], "uniprot_canonical_ac": "Q9BPX6-1" }, { "start_pos": 242, "end_pos": 242, "sequence_org": "E", "sequence_mut": "K", "comment": "Abolishes mitochondrial Ca(2+) uptake; when associated with A-231; A-421 and A-432.", "evidence": [ { "database": "UniProtKB", "id": "Q9BPX6", "url": "https://www.uniprot.org/uniprotkb/Q9BPX6" }, { "database": "PubMed", "id": "24503055", "url": "https://pubmed.ncbi.nlm.nih.gov/24503055" }, { "database": "PubMed", "id": "23101630", "url": "https://pubmed.ncbi.nlm.nih.gov/23101630" }, { "database": "PubMed", "id": "20693986", "url": "https://pubmed.ncbi.nlm.nih.gov/20693986" }, { "database": "PubMed", "id": "37126688", "url": "https://pubmed.ncbi.nlm.nih.gov/37126688" }, { "database": "PubMed", "id": "37036971", "url": "https://pubmed.ncbi.nlm.nih.gov/37036971" } ], "uniprot_canonical_ac": "Q9BPX6-1" }, { "start_pos": 421, "end_pos": 421, "sequence_org": "D", "sequence_mut": "A", "comment": "Abolishes mitochondrial Ca(2+) uptake; when associated with A-231; A-242 and A-432.", "evidence": [ { "database": "UniProtKB", "id": "Q9BPX6", "url": "https://www.uniprot.org/uniprotkb/Q9BPX6" }, { "database": "PubMed", "id": "24503055", "url": "https://pubmed.ncbi.nlm.nih.gov/24503055" }, { "database": "PubMed", "id": "23101630", "url": "https://pubmed.ncbi.nlm.nih.gov/23101630" }, { "database": "PubMed", "id": "20693986", "url": "https://pubmed.ncbi.nlm.nih.gov/20693986" }, { "database": "PubMed", "id": "37126688", "url": "https://pubmed.ncbi.nlm.nih.gov/37126688" }, { "database": "PubMed", "id": "37036971", "url": "https://pubmed.ncbi.nlm.nih.gov/37036971" } ], "uniprot_canonical_ac": "Q9BPX6-1" }, { "start_pos": 432, "end_pos": 432, "sequence_org": "E", "sequence_mut": "A", "comment": "Abolishes mitochondrial Ca(2+) uptake; when associated with A-231; A-242 and A-421.", "evidence": [ { "database": "UniProtKB", "id": "Q9BPX6", "url": "https://www.uniprot.org/uniprotkb/Q9BPX6" }, { "database": "PubMed", "id": "24503055", "url": "https://pubmed.ncbi.nlm.nih.gov/24503055" }, { "database": "PubMed", "id": "23101630", "url": "https://pubmed.ncbi.nlm.nih.gov/23101630" }, { "database": "PubMed", "id": "20693986", "url": "https://pubmed.ncbi.nlm.nih.gov/20693986" }, { "database": "PubMed", "id": "37126688", "url": "https://pubmed.ncbi.nlm.nih.gov/37126688" }, { "database": "PubMed", "id": "37036971", "url": "https://pubmed.ncbi.nlm.nih.gov/37036971" } ], "uniprot_canonical_ac": "Q9BPX6-1" }, { "start_pos": 432, "end_pos": 432, "sequence_org": "E", "sequence_mut": "K", "comment": "Loss of function; when associated with A-421.", "evidence": [ { "database": "UniProtKB", "id": "Q9BPX6", "url": "https://www.uniprot.org/uniprotkb/Q9BPX6" }, { "database": "PubMed", "id": "24503055", "url": "https://pubmed.ncbi.nlm.nih.gov/24503055" }, { "database": "PubMed", "id": "23101630", "url": "https://pubmed.ncbi.nlm.nih.gov/23101630" }, { "database": "PubMed", "id": "20693986", "url": "https://pubmed.ncbi.nlm.nih.gov/20693986" } ], "uniprot_canonical_ac": "Q9BPX6-1" }, { "start_pos": 185, "end_pos": 185, "sequence_org": "D", "sequence_mut": "A", "comment": "Abolishes mitochondrial Ca(2+) uptake; when associated with A-375 and A-386. In EF1(mut); decreased calcium-binding and abolished ability to interact with MICU1 when associated with K-196.", "evidence": [ { "database": "UniProtKB", "id": "Q8IYU8", "url": "https://www.uniprot.org/uniprotkb/Q8IYU8" }, { "database": "PubMed", "id": "32148862", "url": "https://pubmed.ncbi.nlm.nih.gov/32148862" }, { "database": "PubMed", "id": "24503055", "url": "https://pubmed.ncbi.nlm.nih.gov/24503055" }, { "database": "PubMed", "id": "31397067", "url": "https://pubmed.ncbi.nlm.nih.gov/31397067" } ], "uniprot_canonical_ac": "Q8IYU8-1" }, { "start_pos": 375, "end_pos": 375, "sequence_org": "D", "sequence_mut": "A", "comment": "Abolishes mitochondrial Ca(2+) uptake; when associated with A-185 and A-386.", "evidence": [ { "database": "UniProtKB", "id": "Q8IYU8", "url": "https://www.uniprot.org/uniprotkb/Q8IYU8" }, { "database": "PubMed", "id": "24503055", "url": "https://pubmed.ncbi.nlm.nih.gov/24503055" } ], "uniprot_canonical_ac": "Q8IYU8-1" }, { "start_pos": 386, "end_pos": 386, "sequence_org": "E", "sequence_mut": "A", "comment": "Abolishes mitochondrial Ca(2+) uptake; when associated with A-185 and A-375.", "evidence": [ { "database": "UniProtKB", "id": "Q8IYU8", "url": "https://www.uniprot.org/uniprotkb/Q8IYU8" }, { "database": "PubMed", "id": "24503055", "url": "https://pubmed.ncbi.nlm.nih.gov/24503055" } ], "uniprot_canonical_ac": "Q8IYU8-1" } ], "record_id": "pubmed.24503055", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 13 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "MICU1 and MICU2 finely tune the mitochondrial Ca2+ uniporter by exerting opposite effects on MCU activity.", "journal": "Molecular cell", "date": "2014", "authors": "Patron M, Checchetto V, Raffaello A, Teardo E, Vecellio Reane D, Mantoan M, Granatiero V, Szabo I, De Stefani D, Rizzuto R", "reference": { "type": "PubMed", "id": "24560927", "url": "https://pubmed.ncbi.nlm.nih.gov/24560927" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q92667-1", "protein_name": "A-kinase anchor protein 1, mitochondrial", "gene_name": "AKAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95202-1", "protein_name": "Mitochondrial proton/calcium exchanger protein", "gene_name": "LETM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BPX6-1", "protein_name": "Calcium uptake protein 1, mitochondrial", "gene_name": "MICU1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NE86-1", "protein_name": "Calcium uniporter protein, mitochondrial", "gene_name": "MCU", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NWR8-1", "protein_name": "Calcium uniporter regulatory subunit MCUb, mitochondrial", "gene_name": "MCUB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P45880-3", "protein_name": "Non-selective voltage-gated ion channel VDAC2", "gene_name": "VDAC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P21796-1", "protein_name": "Non-selective voltage-gated ion channel VDAC1", "gene_name": "VDAC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86XE3-1", "protein_name": "Calcium uptake protein 3, mitochondrial", "gene_name": "MICU3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H4I9-1", "protein_name": "Essential MCU regulator, mitochondrial", "gene_name": "SMDT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6J4K2-1", "protein_name": "Mitochondrial sodium/calcium exchanger protein", "gene_name": "SLC8B1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8VCX5-1", "protein_name": "Calcium uptake protein 1, mitochondrial", "gene_name": "Micu1", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CD10-1", "protein_name": "Calcium uptake protein 2, mitochondrial", "gene_name": "Micu2", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y277-1", "protein_name": "Non-selective voltage-gated ion channel VDAC3", "gene_name": "VDAC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IYU8-1", "protein_name": "Calcium uptake protein 2, mitochondrial", "gene_name": "MICU2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57103-1", "protein_name": "Sodium/calcium exchanger 3", "gene_name": "SLC8A3", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q92667", "url": "https://www.uniprot.org/uniprotkb/Q92667" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 203, "end_pos": 203, "sequence_org": "C", "sequence_mut": "A", "comment": "No effect.", "evidence": [ { "database": "UniProtKB", "id": "Q8VCX5", "url": "https://www.uniprot.org/uniprotkb/Q8VCX5" }, { "database": "PubMed", "id": "24560927", "url": "https://pubmed.ncbi.nlm.nih.gov/24560927" } ], "uniprot_canonical_ac": "Q8VCX5-1" }, { "start_pos": 233, "end_pos": 233, "sequence_org": "D", "sequence_mut": "A", "comment": "Acts as a dominant negative mutant that reduces the mitochondrial Ca(2+) peaks; when associated with A-244; A-423 and A-434. Does not affect ability to regulate cristae organization; when associated with A-244; A-423 and A-434.", "evidence": [ { "database": "UniProtKB", "id": "Q8VCX5", "url": "https://www.uniprot.org/uniprotkb/Q8VCX5" }, { "database": "PubMed", "id": "37098122", "url": "https://pubmed.ncbi.nlm.nih.gov/37098122" }, { "database": "PubMed", "id": "24560927", "url": "https://pubmed.ncbi.nlm.nih.gov/24560927" } ], "uniprot_canonical_ac": "Q8VCX5-1" }, { "start_pos": 244, "end_pos": 244, "sequence_org": "E", "sequence_mut": "A", "comment": "Acts as a dominant negative mutant that reduces the mitochondrial Ca(2+) peaks; when associated with A-233; A-423 and A-434. Does not affect ability to regulate cristae organization; when associated with A-233; A-423 and A-434.", "evidence": [ { "database": "UniProtKB", "id": "Q8VCX5", "url": "https://www.uniprot.org/uniprotkb/Q8VCX5" }, { "database": "PubMed", "id": "24560927", "url": "https://pubmed.ncbi.nlm.nih.gov/24560927" } ], "uniprot_canonical_ac": "Q8VCX5-1" }, { "start_pos": 277, "end_pos": 277, "sequence_org": "C", "sequence_mut": "A", "comment": "No effect.", "evidence": [ { "database": "UniProtKB", "id": "Q8VCX5", "url": "https://www.uniprot.org/uniprotkb/Q8VCX5" }, { "database": "PubMed", "id": "24560927", "url": "https://pubmed.ncbi.nlm.nih.gov/24560927" } ], "uniprot_canonical_ac": "Q8VCX5-1" }, { "start_pos": 423, "end_pos": 423, "sequence_org": "D", "sequence_mut": "A", "comment": "Acts as a dominant negative mutant that reduces the mitochondrial Ca(2+) peaks; when associated with A-233; A-244 and A-434. Does not affect ability to regulate cristae organization; when associated with A-233; A-244 and A-434.", "evidence": [ { "database": "UniProtKB", "id": "Q8VCX5", "url": "https://www.uniprot.org/uniprotkb/Q8VCX5" }, { "database": "PubMed", "id": "24560927", "url": "https://pubmed.ncbi.nlm.nih.gov/24560927" } ], "uniprot_canonical_ac": "Q8VCX5-1" }, { "start_pos": 434, "end_pos": 434, "sequence_org": "E", "sequence_mut": "A", "comment": "Acts as a dominant negative mutant that reduces the mitochondrial Ca(2+) peaks; when associated with A-233; A-244 and A-423. Does not affect ability to regulate cristae organization; A-233; A-244 and A-423.", "evidence": [ { "database": "UniProtKB", "id": "Q8VCX5", "url": "https://www.uniprot.org/uniprotkb/Q8VCX5" }, { "database": "PubMed", "id": "24560927", "url": "https://pubmed.ncbi.nlm.nih.gov/24560927" } ], "uniprot_canonical_ac": "Q8VCX5-1" }, { "start_pos": 62, "end_pos": 62, "sequence_org": "C", "sequence_mut": "A", "comment": "No effect.", "evidence": [ { "database": "UniProtKB", "id": "Q8VCX5", "url": "https://www.uniprot.org/uniprotkb/Q8VCX5" }, { "database": "PubMed", "id": "24560927", "url": "https://pubmed.ncbi.nlm.nih.gov/24560927" } ], "uniprot_canonical_ac": "Q8VCX5-1" }, { "start_pos": 372, "end_pos": 372, "sequence_org": "D", "sequence_mut": "A", "comment": "Strong reduction of mitochondrial Ca(2+) peaks.", "evidence": [ { "database": "UniProtKB", "id": "Q8CD10", "url": "https://www.uniprot.org/uniprotkb/Q8CD10" }, { "database": "PubMed", "id": "24560927", "url": 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Heart and circulatory physiology", "date": "2018", "authors": "Suryavanshi SV, Jadhav SM, Anderson KL, Katsonis P, Lichtarge O, McConnell BK", "reference": { "type": "PubMed", "id": "29600899", "url": "https://pubmed.ncbi.nlm.nih.gov/29600899" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q13023-1", "protein_name": "A-kinase anchor protein 6", "gene_name": "AKAP6", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q13023", "url": "https://www.uniprot.org/uniprotkb/Q13023" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.29600899", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", 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Dork T, du Bois A, Durst M, Easton DF, Eccles DM, Edwards RP, Ekici AB, Fasching PA, Fridley BL, Gentry-Maharaj A, Giles GG, Glasspool R, Goodman MT, Gronwald J, Harter P, Hein A, Heitz F, Hildebrandt MAT, Hillemanns P, Hogdall CK, Hogdall E, Hosono S, Iversen ES, Jakubowska A, Jensen A, Ji BT, Jung AY, Karlan BY, Kellar M, Kiemeney LA, Kiong Lim B, Kjaer SK, Krakstad C, Kupryjanczyk J, Lambrechts D, Lambrechts S, Le ND, Lele S, Lester J, Levine DA, Li Z, Liang D, Lissowska J, Lu K, Lubinski J, Lundvall L, Massuger LFAG, Matsuo K, McGuire V, McLaughlin JR, McNeish I, Menon U, Milne RL, Modugno F, Moysich KB, Ness RB, Nevanlinna H, Odunsi K, Olson SH, Orlow I, Orsulic S, Paul J, Pejovic T, Pelttari LM, Permuth JB, Pike MC, Poole EM, Rosen B, Rossing MA, Rothstein JH, Runnebaum IB, Rzepecka IK, Schernhammer E, Schwaab I, Shu XO, Shvetsov YB, Siddiqui N, Sieh W, Song H, Southey MC, Spiewankiewicz B, Sucheston-Campbell L, Tangen IL, Teo SH, Terry KL, Thompson PJ, Thomsen L, Tworoger SS, van Altena AM, Vergote I, Vestrheim Thomsen LC, Vierkant RA, Walsh CS, Wang-Gohrke S, Wentzensen N, Whittemore AS, Wicklund KG, Wilkens LR, Woo YL, Wu AH, Wu X, Xiang YB, Yang H, Zheng W, Ziogas A, Lee AW, Pearce CL, Berchuck A, Schildkraut JM, Ramus SJ, Monteiro ANA, Narod SA, Sellers TA, Gayther SA, Kelemen LE, Chenevix-Trench G, Risch HA, Pharoah PDP, Goode EL, Phelan CM", "reference": { "type": "PubMed", "id": "29979793", "url": "https://pubmed.ncbi.nlm.nih.gov/29979793" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q13023-1", "protein_name": "A-kinase anchor protein 6", "gene_name": "AKAP6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HCE6-1", "protein_name": "Rho guanine nucleotide exchange factor 10-like protein", "gene_name": "ARHGEF10L", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q13023", "url": "https://www.uniprot.org/uniprotkb/Q13023" } ], 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"gene_name": "TUBA1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52564-1", "protein_name": "Dual specificity mitogen-activated protein kinase kinase 6", "gene_name": "MAP2K6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BVA1-1", "protein_name": "Tubulin beta-2B chain", "gene_name": "TUBB2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12905-1", "protein_name": "Interleukin enhancer-binding factor 2", "gene_name": "ILF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2Z9-1", "protein_name": "Centromere protein S", "gene_name": "CENPS-CORT; CENPS", "tax_name": "Human" }, { "uniprot_canonical_ac": "A8MT69-1", "protein_name": "Centromere protein X", "gene_name": "CENPX", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14920-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit beta", "gene_name": "IKBKB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62714-1", "protein_name": "Serine/threonine-protein phosphatase 2A catalytic subunit 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{ "uniprot_canonical_ac": "A6NNZ2-1", "protein_name": "Tubulin beta 8B", "gene_name": "TUBB8B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q3ZCM7-1", "protein_name": "Tubulin beta-8 chain", "gene_name": "TUBB8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04350-1", "protein_name": "Tubulin beta-4A chain", "gene_name": "TUBB4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13885-1", "protein_name": "Tubulin beta-2A chain", "gene_name": "TUBB2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z434-1", "protein_name": "Mitochondrial antiviral-signaling protein", "gene_name": "MAVS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06748-1", "protein_name": "Nucleophosmin", "gene_name": "NPM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11142-1", "protein_name": "Heat shock cognate 71 kDa protein", "gene_name": "HSPA8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NW38-1", "protein_name": "E3 ubiquitin-protein ligase FANCL", "gene_name": "FANCL", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15172-1", "protein_name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform", "gene_name": "PPP2R5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12906-1", "protein_name": "Interleukin enhancer-binding factor 3", "gene_name": "ILF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q08211-1", "protein_name": "ATP-dependent RNA helicase A", "gene_name": "DHX9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05198-1", "protein_name": "Eukaryotic translation initiation factor 2 subunit 1", "gene_name": "EIF2S1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HB96-1", "protein_name": "Fanconi anemia group E protein", "gene_name": "FANCE", "tax_name": "Human" }, { "uniprot_canonical_ac": "P17706-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 2", "gene_name": "PTPN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0DPH8-1", "protein_name": "Tubulin alpha-3D chain", "gene_name": "TUBA3D", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40763-1", "protein_name": "Signal transducer and activator of transcription 3", "gene_name": "STAT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P55265-1", "protein_name": "Double-stranded RNA-specific adenosine deaminase", "gene_name": "ADAR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UII4-1", "protein_name": "E3 ISG15--protein ligase HERC5", "gene_name": "HERC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41091-1", "protein_name": "Eukaryotic translation initiation factor 2 subunit 3", "gene_name": "EIF2S3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NB91-1", "protein_name": "Fanconi anemia group B protein", "gene_name": "FANCB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13509-1", "protein_name": "Tubulin beta-3 chain", "gene_name": "TUBB3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BQE3-1", "protein_name": "Tubulin alpha-1C chain", "gene_name": "TUBA1C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68371-1", "protein_name": "Tubulin beta-4B chain", "gene_name": "TUBB4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H4B7-1", "protein_name": "Tubulin beta-1 chain", "gene_name": "TUBB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H853-1", "protein_name": "Tubulin-like protein alpha-4B", "gene_name": "TUBA4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19525-1", "protein_name": "Interferon-induced, double-stranded RNA-activated protein kinase", "gene_name": "EIF2AK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42224-1", "protein_name": "Signal transducer and activator of transcription 1-alpha/beta", "gene_name": "STAT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NX74-1", "protein_name": "tRNA-dihydrouridine(20) synthase [NAD(P)+]-like", "gene_name": "DUS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13217-1", "protein_name": "DnaJ homolog subfamily C member 3", "gene_name": "DNAJC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15360-1", "protein_name": "Fanconi anemia group A protein", "gene_name": "FANCA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q0VG06-1", "protein_name": "Fanconi anemia core complex-associated protein 100", "gene_name": "FAAP100", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15287-1", "protein_name": "Fanconi anemia group G protein", "gene_name": "FANCG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6NZ36-1", "protein_name": "Fanconi anemia core complex-associated protein 20", "gene_name": "FAAP20", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BTP7-1", "protein_name": "Fanconi anemia core complex-associated protein 24", "gene_name": "FAAP24", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NPI8-1", "protein_name": "Fanconi anemia group F protein", "gene_name": "FANCF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0DMV9-1", "protein_name": "Heat shock 70 kDa protein 1B", "gene_name": "HSPA1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "A6NHL2-1", "protein_name": "Tubulin alpha chain-like 3", "gene_name": "TUBAL3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY65-1", "protein_name": "Tubulin alpha-8 chain", "gene_name": "TUBA8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IYD8-1", "protein_name": "Fanconi anemia group M protein", "gene_name": "FANCM", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05161-1", "protein_name": "Ubiquitin-like protein ISG15", "gene_name": "ISG15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q00597-1", "protein_name": "Fanconi anemia group C protein", "gene_name": "FANCC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0DPH7-1", "protein_name": "Tubulin alpha-3C chain", "gene_name": "TUBA3C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16333-1", "protein_name": "SH2/SH3 adapter protein NCK1", "gene_name": "NCK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6K9-1", "protein_name": "NF-kappa-B essential modulator", "gene_name": "IKBKG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30154-1", "protein_name": "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform", "gene_name": "PPP2R1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0DMV8-1", "protein_name": "Heat shock 70 kDa protein 1A", "gene_name": "HSPA1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30153-1", "protein_name": "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform", "gene_name": "PPP2R1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P67775-1", "protein_name": "Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform", "gene_name": "PPP2CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37840-1", "protein_name": "Alpha-synuclein", "gene_name": "SNCA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04637-1", "protein_name": "Cellular tumor antigen p53", "gene_name": "TP53", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O75569", "url": "https://www.uniprot.org/uniprotkb/O75569" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.10400669", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 75 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "HIV-I TAT inhibits PKR activity by both RNA-dependent and RNA-independent mechanisms.", "journal": "Archives of biochemistry and biophysics", "date": "2000-01-15", "authors": "Cai R, Carpick B, Chun R F, Jeang K T, Williams B R", "reference": { "type": "PubMed", "id": "10620360", "url": "https://pubmed.ncbi.nlm.nih.gov/10620360" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O75569-1", "protein_name": "Interferon-inducible double-stranded RNA-dependent protein kinase activator A", "gene_name": "PRKRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y4X5-1", "protein_name": "E3 ubiquitin-protein ligase ARIH1", "gene_name": "ARIH1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15633-1", "protein_name": "RISC-loading complex subunit TARBP2", "gene_name": "TARBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15111-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit alpha", "gene_name": "CHUK", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14933-1", "protein_name": "Ubiquitin/ISG15-conjugating enzyme E2 L6", "gene_name": "UBE2L6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68363-1", "protein_name": "Tubulin alpha-1B chain", "gene_name": "TUBA1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6PEY2-1", "protein_name": "Tubulin alpha-3E chain", "gene_name": "TUBA3E", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68366-1", "protein_name": "Tubulin alpha-4A chain", "gene_name": "TUBA4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q71U36-1", "protein_name": "Tubulin alpha-1A chain", "gene_name": "TUBA1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52564-1", "protein_name": "Dual specificity mitogen-activated protein kinase kinase 6", "gene_name": "MAP2K6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BVA1-1", "protein_name": "Tubulin beta-2B chain", "gene_name": "TUBB2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12905-1", "protein_name": "Interleukin enhancer-binding factor 2", "gene_name": "ILF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2Z9-1", "protein_name": "Centromere protein S", "gene_name": "CENPS-CORT; CENPS", "tax_name": "Human" }, { "uniprot_canonical_ac": "A8MT69-1", "protein_name": "Centromere protein X", "gene_name": "CENPX", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14920-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit beta", "gene_name": "IKBKB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62714-1", "protein_name": "Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform", "gene_name": "PPP2CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14258-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "TRIM25", "tax_name": "Human" }, { "uniprot_canonical_ac": "P34931-1", "protein_name": "Heat shock 70 kDa protein 1-like", "gene_name": "HSPA1L", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54652-1", "protein_name": "Heat shock-related 70 kDa protein 2", "gene_name": "HSPA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20042-1", "protein_name": "Eukaryotic translation initiation factor 2 subunit 2", "gene_name": "EIF2S2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06493-1", "protein_name": "Cyclin-dependent kinase 1", "gene_name": "CDK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYA1-1", "protein_name": "Sphingosine kinase 1", "gene_name": "SPHK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BUF5-1", "protein_name": "Tubulin beta-6 chain", "gene_name": "TUBB6", "tax_name": "Human" }, { "uniprot_canonical_ac": "A6NNZ2-1", "protein_name": "Tubulin beta 8B", "gene_name": "TUBB8B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q3ZCM7-1", "protein_name": "Tubulin beta-8 chain", "gene_name": "TUBB8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04350-1", "protein_name": "Tubulin beta-4A chain", "gene_name": "TUBB4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13885-1", "protein_name": "Tubulin beta-2A chain", "gene_name": "TUBB2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z434-1", "protein_name": "Mitochondrial antiviral-signaling protein", "gene_name": "MAVS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06748-1", "protein_name": "Nucleophosmin", "gene_name": "NPM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11142-1", "protein_name": "Heat shock cognate 71 kDa protein", "gene_name": "HSPA8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NW38-1", "protein_name": "E3 ubiquitin-protein ligase FANCL", "gene_name": "FANCL", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15172-1", "protein_name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform", "gene_name": "PPP2R5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12906-1", "protein_name": "Interleukin enhancer-binding factor 3", "gene_name": "ILF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q08211-1", "protein_name": "ATP-dependent RNA helicase A", "gene_name": "DHX9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05198-1", "protein_name": "Eukaryotic translation initiation factor 2 subunit 1", "gene_name": "EIF2S1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HB96-1", "protein_name": "Fanconi anemia group E protein", "gene_name": "FANCE", "tax_name": "Human" }, { "uniprot_canonical_ac": "P17706-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 2", "gene_name": "PTPN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0DPH8-1", "protein_name": "Tubulin alpha-3D chain", "gene_name": "TUBA3D", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40763-1", "protein_name": "Signal transducer and activator of transcription 3", "gene_name": "STAT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P55265-1", "protein_name": "Double-stranded RNA-specific adenosine deaminase", "gene_name": "ADAR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UII4-1", "protein_name": "E3 ISG15--protein ligase HERC5", "gene_name": "HERC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41091-1", "protein_name": "Eukaryotic translation initiation factor 2 subunit 3", "gene_name": "EIF2S3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NB91-1", "protein_name": "Fanconi anemia group B protein", "gene_name": "FANCB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13509-1", "protein_name": "Tubulin beta-3 chain", "gene_name": "TUBB3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BQE3-1", "protein_name": "Tubulin alpha-1C chain", "gene_name": "TUBA1C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68371-1", "protein_name": "Tubulin beta-4B chain", "gene_name": "TUBB4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H4B7-1", "protein_name": "Tubulin beta-1 chain", "gene_name": "TUBB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H853-1", "protein_name": "Tubulin-like protein alpha-4B", "gene_name": "TUBA4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19525-1", "protein_name": "Interferon-induced, double-stranded RNA-activated protein kinase", "gene_name": "EIF2AK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42224-1", "protein_name": "Signal transducer and activator of transcription 1-alpha/beta", "gene_name": "STAT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NX74-1", "protein_name": "tRNA-dihydrouridine(20) synthase [NAD(P)+]-like", "gene_name": "DUS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13217-1", "protein_name": "DnaJ homolog subfamily C member 3", "gene_name": "DNAJC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15360-1", "protein_name": "Fanconi anemia group A protein", "gene_name": "FANCA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q0VG06-1", "protein_name": "Fanconi anemia core complex-associated protein 100", "gene_name": "FAAP100", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15287-1", "protein_name": "Fanconi anemia group G protein", "gene_name": "FANCG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6NZ36-1", "protein_name": "Fanconi anemia core complex-associated protein 20", "gene_name": "FAAP20", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BTP7-1", "protein_name": "Fanconi anemia core complex-associated protein 24", "gene_name": "FAAP24", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NPI8-1", "protein_name": "Fanconi anemia group F protein", "gene_name": "FANCF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0DMV9-1", "protein_name": "Heat shock 70 kDa protein 1B", "gene_name": "HSPA1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "A6NHL2-1", "protein_name": "Tubulin alpha chain-like 3", "gene_name": "TUBAL3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY65-1", "protein_name": "Tubulin alpha-8 chain", "gene_name": "TUBA8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IYD8-1", "protein_name": "Fanconi anemia group M protein", "gene_name": "FANCM", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05161-1", "protein_name": "Ubiquitin-like protein ISG15", "gene_name": "ISG15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q00597-1", "protein_name": "Fanconi anemia group C protein", "gene_name": "FANCC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0DPH7-1", "protein_name": "Tubulin alpha-3C 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"uniprot_canonical_ac": "P37840-1", "protein_name": "Alpha-synuclein", "gene_name": "SNCA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04637-1", "protein_name": "Cellular tumor antigen p53", "gene_name": "TP53", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O75569", "url": "https://www.uniprot.org/uniprotkb/O75569" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.10620360", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 75 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ 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"uniprot_canonical_ac": "A6NNZ2-1", "protein_name": "Tubulin beta 8B", "gene_name": "TUBB8B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q3ZCM7-1", "protein_name": "Tubulin beta-8 chain", "gene_name": "TUBB8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04350-1", "protein_name": "Tubulin beta-4A chain", "gene_name": "TUBB4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13885-1", "protein_name": "Tubulin beta-2A chain", "gene_name": "TUBB2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z434-1", "protein_name": "Mitochondrial antiviral-signaling protein", "gene_name": "MAVS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06748-1", "protein_name": "Nucleophosmin", "gene_name": "NPM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11142-1", "protein_name": "Heat shock cognate 71 kDa protein", "gene_name": "HSPA8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NW38-1", "protein_name": "E3 ubiquitin-protein ligase FANCL", "gene_name": "FANCL", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15172-1", "protein_name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform", "gene_name": "PPP2R5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12906-1", "protein_name": "Interleukin enhancer-binding factor 3", "gene_name": "ILF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q08211-1", "protein_name": "ATP-dependent RNA helicase A", "gene_name": "DHX9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05198-1", "protein_name": "Eukaryotic translation initiation factor 2 subunit 1", "gene_name": "EIF2S1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HB96-1", "protein_name": "Fanconi anemia group E protein", "gene_name": "FANCE", "tax_name": "Human" }, { "uniprot_canonical_ac": "P17706-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 2", "gene_name": "PTPN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0DPH8-1", "protein_name": "Tubulin alpha-3D chain", "gene_name": "TUBA3D", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40763-1", "protein_name": "Signal transducer and activator of transcription 3", "gene_name": "STAT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P55265-1", "protein_name": "Double-stranded RNA-specific adenosine deaminase", "gene_name": "ADAR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UII4-1", "protein_name": "E3 ISG15--protein ligase HERC5", "gene_name": "HERC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41091-1", "protein_name": "Eukaryotic translation initiation factor 2 subunit 3", "gene_name": "EIF2S3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NB91-1", "protein_name": "Fanconi anemia group B protein", "gene_name": "FANCB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13509-1", "protein_name": "Tubulin beta-3 chain", "gene_name": "TUBB3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BQE3-1", "protein_name": "Tubulin alpha-1C chain", "gene_name": "TUBA1C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68371-1", "protein_name": "Tubulin beta-4B chain", "gene_name": "TUBB4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H4B7-1", "protein_name": "Tubulin beta-1 chain", "gene_name": "TUBB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H853-1", "protein_name": "Tubulin-like protein alpha-4B", "gene_name": "TUBA4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19525-1", "protein_name": "Interferon-induced, double-stranded RNA-activated protein kinase", "gene_name": "EIF2AK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42224-1", "protein_name": "Signal transducer and activator of transcription 1-alpha/beta", "gene_name": "STAT1", "tax_name": 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"tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NPI8-1", "protein_name": "Fanconi anemia group F protein", "gene_name": "FANCF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0DMV9-1", "protein_name": "Heat shock 70 kDa protein 1B", "gene_name": "HSPA1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "A6NHL2-1", "protein_name": "Tubulin alpha chain-like 3", "gene_name": "TUBAL3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY65-1", "protein_name": "Tubulin alpha-8 chain", "gene_name": "TUBA8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IYD8-1", "protein_name": "Fanconi anemia group M protein", "gene_name": "FANCM", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05161-1", "protein_name": "Ubiquitin-like protein ISG15", "gene_name": "ISG15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q00597-1", "protein_name": "Fanconi anemia group C protein", "gene_name": "FANCC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0DPH7-1", "protein_name": "Tubulin alpha-3C chain", "gene_name": "TUBA3C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16333-1", "protein_name": "SH2/SH3 adapter protein NCK1", "gene_name": "NCK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6K9-1", "protein_name": "NF-kappa-B essential modulator", "gene_name": "IKBKG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30154-1", "protein_name": "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform", "gene_name": "PPP2R1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0DMV8-1", "protein_name": "Heat shock 70 kDa protein 1A", "gene_name": "HSPA1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30153-1", "protein_name": "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform", "gene_name": "PPP2R1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P67775-1", "protein_name": "Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform", "gene_name": "PPP2CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37840-1", "protein_name": "Alpha-synuclein", "gene_name": "SNCA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04637-1", "protein_name": "Cellular tumor antigen p53", "gene_name": "TP53", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O75569", "url": "https://www.uniprot.org/uniprotkb/O75569" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.10648614", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 75 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "PKR stimulates NF-kappaB irrespective of its kinase function by interacting with the IkappaB kinase complex.", "journal": "Molecular and cellular biology", "date": "2000-07", "authors": "Bonnet M C, Weil R, Dam E, Hovanessian A G, Meurs E F", "reference": { "type": "PubMed", "id": "10848580", "url": "https://pubmed.ncbi.nlm.nih.gov/10848580" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O75569-1", "protein_name": "Interferon-inducible double-stranded RNA-dependent protein kinase activator A", "gene_name": "PRKRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y4X5-1", "protein_name": "E3 ubiquitin-protein ligase ARIH1", "gene_name": "ARIH1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15633-1", "protein_name": "RISC-loading complex subunit TARBP2", "gene_name": "TARBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15111-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit alpha", "gene_name": "CHUK", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14933-1", "protein_name": "Ubiquitin/ISG15-conjugating enzyme E2 L6", "gene_name": "UBE2L6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68363-1", "protein_name": "Tubulin alpha-1B chain", "gene_name": "TUBA1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6PEY2-1", "protein_name": "Tubulin alpha-3E chain", "gene_name": "TUBA3E", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68366-1", "protein_name": "Tubulin alpha-4A chain", "gene_name": "TUBA4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q71U36-1", "protein_name": "Tubulin alpha-1A chain", "gene_name": "TUBA1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52564-1", "protein_name": "Dual specificity mitogen-activated protein kinase kinase 6", "gene_name": "MAP2K6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BVA1-1", "protein_name": "Tubulin beta-2B chain", "gene_name": "TUBB2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12905-1", "protein_name": "Interleukin enhancer-binding factor 2", "gene_name": "ILF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2Z9-1", "protein_name": "Centromere protein S", "gene_name": "CENPS-CORT; CENPS", "tax_name": "Human" }, { "uniprot_canonical_ac": "A8MT69-1", "protein_name": "Centromere protein X", "gene_name": "CENPX", "tax_name": "Human" }, { "uniprot_canonical_ac": "O88351-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit beta", "gene_name": "Ikbkb", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "O14920-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit beta", "gene_name": "IKBKB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62714-1", "protein_name": "Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform", "gene_name": "PPP2CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14258-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "TRIM25", "tax_name": "Human" }, { "uniprot_canonical_ac": "P34931-1", "protein_name": "Heat shock 70 kDa protein 1-like", "gene_name": "HSPA1L", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54652-1", "protein_name": "Heat shock-related 70 kDa protein 2", "gene_name": "HSPA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20042-1", "protein_name": "Eukaryotic translation initiation factor 2 subunit 2", "gene_name": "EIF2S2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06493-1", "protein_name": "Cyclin-dependent kinase 1", "gene_name": "CDK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYA1-1", "protein_name": "Sphingosine kinase 1", "gene_name": "SPHK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BUF5-1", "protein_name": "Tubulin beta-6 chain", "gene_name": "TUBB6", "tax_name": "Human" }, { "uniprot_canonical_ac": "A6NNZ2-1", "protein_name": "Tubulin beta 8B", "gene_name": "TUBB8B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q3ZCM7-1", "protein_name": "Tubulin beta-8 chain", "gene_name": "TUBB8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04350-1", "protein_name": "Tubulin beta-4A chain", "gene_name": "TUBB4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13885-1", "protein_name": "Tubulin beta-2A chain", "gene_name": "TUBB2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z434-1", "protein_name": "Mitochondrial antiviral-signaling protein", "gene_name": "MAVS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06748-1", "protein_name": "Nucleophosmin", "gene_name": "NPM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11142-1", "protein_name": "Heat shock cognate 71 kDa protein", "gene_name": "HSPA8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NW38-1", "protein_name": "E3 ubiquitin-protein ligase FANCL", "gene_name": "FANCL", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15172-1", "protein_name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform", "gene_name": "PPP2R5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12906-1", "protein_name": "Interleukin enhancer-binding factor 3", "gene_name": "ILF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q08211-1", "protein_name": "ATP-dependent RNA helicase A", "gene_name": "DHX9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05198-1", "protein_name": "Eukaryotic translation initiation factor 2 subunit 1", "gene_name": "EIF2S1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03963-1", "protein_name": "Interferon-induced, double-stranded RNA-activated protein kinase", "gene_name": "Eif2ak2", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q9HB96-1", "protein_name": "Fanconi anemia group E protein", "gene_name": "FANCE", "tax_name": "Human" }, { "uniprot_canonical_ac": "P17706-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 2", "gene_name": "PTPN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0DPH8-1", "protein_name": "Tubulin alpha-3D chain", "gene_name": "TUBA3D", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40763-1", "protein_name": "Signal transducer and activator of transcription 3", "gene_name": "STAT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P55265-1", "protein_name": "Double-stranded RNA-specific adenosine deaminase", "gene_name": "ADAR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UII4-1", "protein_name": "E3 ISG15--protein ligase HERC5", "gene_name": "HERC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41091-1", "protein_name": "Eukaryotic translation initiation factor 2 subunit 3", "gene_name": "EIF2S3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NB91-1", "protein_name": "Fanconi anemia group B protein", "gene_name": "FANCB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13509-1", "protein_name": "Tubulin beta-3 chain", "gene_name": "TUBB3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BQE3-1", "protein_name": "Tubulin alpha-1C chain", "gene_name": "TUBA1C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68371-1", "protein_name": "Tubulin beta-4B chain", "gene_name": "TUBB4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H4B7-1", "protein_name": "Tubulin beta-1 chain", "gene_name": "TUBB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H853-1", "protein_name": "Tubulin-like protein alpha-4B", "gene_name": "TUBA4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19525-1", "protein_name": "Interferon-induced, double-stranded RNA-activated protein kinase", "gene_name": "EIF2AK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42224-1", "protein_name": "Signal transducer and activator of transcription 1-alpha/beta", "gene_name": "STAT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NX74-1", "protein_name": "tRNA-dihydrouridine(20) synthase [NAD(P)+]-like", "gene_name": "DUS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13217-1", "protein_name": "DnaJ homolog subfamily C member 3", "gene_name": "DNAJC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15360-1", "protein_name": "Fanconi anemia group A protein", "gene_name": "FANCA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q0VG06-1", "protein_name": "Fanconi anemia core complex-associated protein 100", "gene_name": "FAAP100", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15287-1", "protein_name": "Fanconi anemia group G protein", "gene_name": "FANCG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6NZ36-1", "protein_name": "Fanconi anemia core complex-associated protein 20", "gene_name": "FAAP20", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BTP7-1", "protein_name": "Fanconi anemia core complex-associated protein 24", "gene_name": "FAAP24", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NPI8-1", "protein_name": "Fanconi anemia group F protein", "gene_name": "FANCF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0DMV9-1", "protein_name": "Heat shock 70 kDa protein 1B", "gene_name": "HSPA1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "A6NHL2-1", "protein_name": "Tubulin alpha chain-like 3", "gene_name": "TUBAL3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY65-1", "protein_name": "Tubulin alpha-8 chain", "gene_name": "TUBA8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IYD8-1", "protein_name": "Fanconi anemia group M protein", "gene_name": "FANCM", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05161-1", "protein_name": "Ubiquitin-like protein ISG15", "gene_name": "ISG15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q00597-1", "protein_name": "Fanconi anemia group C protein", "gene_name": "FANCC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0DPH7-1", "protein_name": "Tubulin alpha-3C chain", "gene_name": "TUBA3C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16333-1", "protein_name": "SH2/SH3 adapter protein NCK1", "gene_name": "NCK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6K9-1", "protein_name": "NF-kappa-B essential modulator", "gene_name": "IKBKG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30154-1", "protein_name": "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform", "gene_name": "PPP2R1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0DMV8-1", "protein_name": "Heat shock 70 kDa protein 1A", "gene_name": "HSPA1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30153-1", "protein_name": "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform", "gene_name": "PPP2R1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P67775-1", "protein_name": "Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform", "gene_name": "PPP2CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37840-1", "protein_name": "Alpha-synuclein", "gene_name": "SNCA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04637-1", "protein_name": "Cellular tumor antigen p53", "gene_name": "TP53", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O75569", "url": "https://www.uniprot.org/uniprotkb/O75569" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.10848580", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 77 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The B56alpha regulatory subunit of protein phosphatase 2A is a target for regulation by double-stranded RNA-dependent protein kinase PKR.", "journal": "Molecular and cellular biology", "date": "2000", "authors": "Xu Z, Williams BR", "reference": { "type": "PubMed", "id": "10866685", "url": "https://pubmed.ncbi.nlm.nih.gov/10866685" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O75569-1", "protein_name": "Interferon-inducible double-stranded RNA-dependent protein kinase activator A", "gene_name": "PRKRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y4X5-1", "protein_name": "E3 ubiquitin-protein ligase ARIH1", "gene_name": "ARIH1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15633-1", "protein_name": "RISC-loading complex subunit TARBP2", "gene_name": "TARBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15111-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit alpha", "gene_name": "CHUK", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14933-1", "protein_name": "Ubiquitin/ISG15-conjugating enzyme E2 L6", "gene_name": "UBE2L6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68363-1", "protein_name": "Tubulin alpha-1B chain", "gene_name": "TUBA1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6PEY2-1", "protein_name": "Tubulin alpha-3E chain", "gene_name": "TUBA3E", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68366-1", "protein_name": "Tubulin alpha-4A chain", "gene_name": "TUBA4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q71U36-1", "protein_name": "Tubulin alpha-1A chain", "gene_name": "TUBA1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52564-1", "protein_name": "Dual specificity mitogen-activated protein kinase kinase 6", "gene_name": "MAP2K6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BVA1-1", "protein_name": "Tubulin beta-2B chain", "gene_name": "TUBB2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12905-1", "protein_name": "Interleukin enhancer-binding factor 2", "gene_name": "ILF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2Z9-1", "protein_name": "Centromere protein S", "gene_name": "CENPS-CORT; CENPS", "tax_name": "Human" }, { "uniprot_canonical_ac": "A8MT69-1", "protein_name": "Centromere protein X", "gene_name": "CENPX", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14920-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit beta", "gene_name": "IKBKB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62714-1", "protein_name": "Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform", "gene_name": "PPP2CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14258-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "TRIM25", "tax_name": "Human" }, { "uniprot_canonical_ac": "P34931-1", "protein_name": "Heat shock 70 kDa protein 1-like", "gene_name": "HSPA1L", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54652-1", "protein_name": "Heat shock-related 70 kDa protein 2", "gene_name": "HSPA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20042-1", "protein_name": "Eukaryotic translation initiation factor 2 subunit 2", "gene_name": "EIF2S2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06493-1", "protein_name": "Cyclin-dependent kinase 1", "gene_name": "CDK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYA1-1", "protein_name": "Sphingosine kinase 1", "gene_name": "SPHK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BUF5-1", "protein_name": "Tubulin beta-6 chain", "gene_name": "TUBB6", "tax_name": "Human" }, { "uniprot_canonical_ac": "A6NNZ2-1", "protein_name": "Tubulin beta 8B", "gene_name": "TUBB8B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q3ZCM7-1", "protein_name": "Tubulin beta-8 chain", "gene_name": "TUBB8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04350-1", "protein_name": "Tubulin beta-4A chain", "gene_name": "TUBB4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13885-1", "protein_name": "Tubulin beta-2A chain", "gene_name": "TUBB2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z434-1", "protein_name": "Mitochondrial antiviral-signaling protein", "gene_name": "MAVS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06748-1", "protein_name": "Nucleophosmin", "gene_name": "NPM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11142-1", "protein_name": "Heat shock cognate 71 kDa protein", "gene_name": "HSPA8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NW38-1", "protein_name": "E3 ubiquitin-protein ligase FANCL", "gene_name": "FANCL", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15172-1", "protein_name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform", "gene_name": "PPP2R5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12906-1", "protein_name": "Interleukin enhancer-binding factor 3", "gene_name": "ILF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q08211-1", "protein_name": "ATP-dependent RNA helicase A", "gene_name": "DHX9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05198-1", "protein_name": "Eukaryotic translation initiation factor 2 subunit 1", "gene_name": "EIF2S1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HB96-1", "protein_name": "Fanconi anemia group E protein", "gene_name": "FANCE", "tax_name": "Human" }, { "uniprot_canonical_ac": "P17706-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 2", "gene_name": "PTPN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0DPH8-1", "protein_name": "Tubulin alpha-3D chain", "gene_name": "TUBA3D", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40763-1", "protein_name": "Signal transducer and activator of transcription 3", "gene_name": "STAT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P55265-1", "protein_name": "Double-stranded RNA-specific adenosine deaminase", "gene_name": "ADAR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UII4-1", "protein_name": "E3 ISG15--protein ligase HERC5", "gene_name": "HERC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41091-1", "protein_name": "Eukaryotic translation initiation factor 2 subunit 3", "gene_name": "EIF2S3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NB91-1", "protein_name": "Fanconi anemia group B protein", "gene_name": "FANCB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13509-1", "protein_name": "Tubulin beta-3 chain", "gene_name": "TUBB3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BQE3-1", "protein_name": "Tubulin alpha-1C chain", "gene_name": "TUBA1C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68371-1", "protein_name": "Tubulin beta-4B chain", "gene_name": "TUBB4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H4B7-1", "protein_name": "Tubulin beta-1 chain", "gene_name": "TUBB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H853-1", "protein_name": "Tubulin-like protein alpha-4B", "gene_name": "TUBA4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19525-1", "protein_name": "Interferon-induced, double-stranded RNA-activated protein kinase", "gene_name": "EIF2AK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42224-1", "protein_name": "Signal transducer and activator of transcription 1-alpha/beta", "gene_name": "STAT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NX74-1", "protein_name": "tRNA-dihydrouridine(20) synthase [NAD(P)+]-like", "gene_name": "DUS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13217-1", "protein_name": "DnaJ homolog subfamily C member 3", "gene_name": "DNAJC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15360-1", "protein_name": "Fanconi anemia group A protein", "gene_name": "FANCA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q0VG06-1", "protein_name": "Fanconi anemia core complex-associated protein 100", "gene_name": "FAAP100", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15287-1", "protein_name": "Fanconi anemia group G protein", "gene_name": "FANCG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6NZ36-1", "protein_name": "Fanconi anemia core complex-associated protein 20", "gene_name": "FAAP20", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BTP7-1", "protein_name": "Fanconi anemia core complex-associated protein 24", "gene_name": "FAAP24", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NPI8-1", "protein_name": "Fanconi anemia group F protein", "gene_name": "FANCF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0DMV9-1", "protein_name": "Heat shock 70 kDa protein 1B", "gene_name": "HSPA1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "A6NHL2-1", "protein_name": "Tubulin alpha chain-like 3", "gene_name": "TUBAL3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY65-1", "protein_name": "Tubulin alpha-8 chain", "gene_name": "TUBA8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IYD8-1", "protein_name": "Fanconi anemia group M protein", "gene_name": "FANCM", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05161-1", "protein_name": "Ubiquitin-like protein ISG15", "gene_name": "ISG15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q00597-1", "protein_name": "Fanconi anemia group C protein", "gene_name": "FANCC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0DPH7-1", "protein_name": "Tubulin alpha-3C chain", "gene_name": "TUBA3C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16333-1", "protein_name": "SH2/SH3 adapter protein NCK1", "gene_name": "NCK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6K9-1", "protein_name": "NF-kappa-B essential modulator", "gene_name": "IKBKG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30154-1", "protein_name": "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform", "gene_name": "PPP2R1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0DMV8-1", "protein_name": "Heat shock 70 kDa protein 1A", "gene_name": "HSPA1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30153-1", "protein_name": "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform", "gene_name": "PPP2R1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P67775-1", "protein_name": "Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform", "gene_name": "PPP2CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37840-1", "protein_name": "Alpha-synuclein", "gene_name": "SNCA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04637-1", "protein_name": "Cellular tumor antigen p53", "gene_name": "TP53", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O75569", "url": "https://www.uniprot.org/uniprotkb/O75569" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 28, "end_pos": 28, "kinase_uniprot_canonical_ac": "P19525-1", "kinase_gene_name": "EIF2AK2", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "Q15172", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q15172" }, { "database": "PubMed", "id": "10866685", "url": "https://pubmed.ncbi.nlm.nih.gov/10866685" }, { "database": "PubMed", "id": "18957415", "url": "https://pubmed.ncbi.nlm.nih.gov/18957415" } ], "site_lbl": "Ser28", "uniprot_canonical_ac": "Q15172-1" } ], "record_id": "pubmed.10866685", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 75 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "A Role of RNA Helicase A in cis-Acting Transactivation Response Element-mediated Transcriptional Regulation of Human Immunodeficiency Virus Type 1.", "journal": "The Journal of biological chemistry", "date": "2001-02-23", "authors": "Fujii R, Okamoto M, Aratani S, Oishi T, Ohshima T, Taira K, Baba M, Fukamizu A, Nakajima T", "reference": { "type": "PubMed", "id": "11096080", "url": "https://pubmed.ncbi.nlm.nih.gov/11096080" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O75569-1", "protein_name": "Interferon-inducible double-stranded RNA-dependent protein kinase activator A", "gene_name": "PRKRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y4X5-1", "protein_name": "E3 ubiquitin-protein ligase ARIH1", "gene_name": "ARIH1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15633-1", "protein_name": "RISC-loading complex subunit TARBP2", "gene_name": "TARBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15111-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit alpha", "gene_name": "CHUK", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14933-1", "protein_name": "Ubiquitin/ISG15-conjugating enzyme E2 L6", "gene_name": "UBE2L6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68363-1", "protein_name": "Tubulin alpha-1B chain", "gene_name": "TUBA1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6PEY2-1", "protein_name": "Tubulin alpha-3E chain", "gene_name": "TUBA3E", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68366-1", "protein_name": "Tubulin alpha-4A chain", "gene_name": "TUBA4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q71U36-1", "protein_name": "Tubulin alpha-1A chain", "gene_name": "TUBA1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52564-1", "protein_name": "Dual specificity mitogen-activated protein kinase kinase 6", "gene_name": "MAP2K6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BVA1-1", "protein_name": "Tubulin beta-2B chain", "gene_name": "TUBB2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12905-1", "protein_name": "Interleukin enhancer-binding factor 2", "gene_name": "ILF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2Z9-1", "protein_name": "Centromere protein S", "gene_name": "CENPS-CORT; CENPS", "tax_name": "Human" }, { "uniprot_canonical_ac": "A8MT69-1", "protein_name": "Centromere protein X", "gene_name": "CENPX", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14920-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit beta", "gene_name": "IKBKB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62714-1", "protein_name": "Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform", "gene_name": "PPP2CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14258-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "TRIM25", "tax_name": "Human" }, { "uniprot_canonical_ac": "P34931-1", "protein_name": "Heat shock 70 kDa protein 1-like", "gene_name": "HSPA1L", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54652-1", "protein_name": "Heat shock-related 70 kDa protein 2", "gene_name": "HSPA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20042-1", "protein_name": "Eukaryotic translation initiation factor 2 subunit 2", "gene_name": "EIF2S2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06493-1", "protein_name": "Cyclin-dependent kinase 1", "gene_name": "CDK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYA1-1", "protein_name": "Sphingosine kinase 1", "gene_name": "SPHK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BUF5-1", "protein_name": "Tubulin beta-6 chain", "gene_name": "TUBB6", "tax_name": "Human" }, { "uniprot_canonical_ac": "A6NNZ2-1", "protein_name": "Tubulin beta 8B", "gene_name": "TUBB8B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q3ZCM7-1", "protein_name": "Tubulin beta-8 chain", "gene_name": "TUBB8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04350-1", "protein_name": "Tubulin beta-4A chain", "gene_name": "TUBB4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13885-1", "protein_name": "Tubulin beta-2A chain", "gene_name": "TUBB2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z434-1", "protein_name": "Mitochondrial antiviral-signaling protein", "gene_name": "MAVS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06748-1", "protein_name": "Nucleophosmin", "gene_name": "NPM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11142-1", "protein_name": "Heat shock cognate 71 kDa protein", "gene_name": "HSPA8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NW38-1", "protein_name": "E3 ubiquitin-protein ligase FANCL", "gene_name": "FANCL", "tax_name": "Human" }, { 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"Human" }, { "uniprot_canonical_ac": "P17706-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 2", "gene_name": "PTPN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0DPH8-1", "protein_name": "Tubulin alpha-3D chain", "gene_name": "TUBA3D", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40763-1", "protein_name": "Signal transducer and activator of transcription 3", "gene_name": "STAT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P55265-1", "protein_name": "Double-stranded RNA-specific adenosine deaminase", "gene_name": "ADAR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UII4-1", "protein_name": "E3 ISG15--protein ligase HERC5", "gene_name": "HERC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41091-1", "protein_name": "Eukaryotic translation initiation factor 2 subunit 3", "gene_name": "EIF2S3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NB91-1", "protein_name": "Fanconi anemia group B protein", "gene_name": "FANCB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13509-1", "protein_name": "Tubulin beta-3 chain", "gene_name": "TUBB3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BQE3-1", "protein_name": "Tubulin alpha-1C chain", "gene_name": "TUBA1C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68371-1", "protein_name": "Tubulin beta-4B chain", "gene_name": "TUBB4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H4B7-1", "protein_name": "Tubulin beta-1 chain", "gene_name": "TUBB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H853-1", "protein_name": "Tubulin-like protein alpha-4B", "gene_name": "TUBA4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19525-1", "protein_name": "Interferon-induced, double-stranded RNA-activated protein kinase", "gene_name": "EIF2AK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42224-1", "protein_name": "Signal transducer and activator of transcription 1-alpha/beta", "gene_name": "STAT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NX74-1", "protein_name": "tRNA-dihydrouridine(20) synthase [NAD(P)+]-like", "gene_name": "DUS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13217-1", "protein_name": "DnaJ homolog subfamily C member 3", "gene_name": "DNAJC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15360-1", "protein_name": "Fanconi anemia group A protein", "gene_name": "FANCA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q0VG06-1", "protein_name": "Fanconi anemia core complex-associated protein 100", "gene_name": "FAAP100", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15287-1", "protein_name": "Fanconi anemia group G protein", "gene_name": "FANCG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6NZ36-1", "protein_name": "Fanconi anemia core complex-associated protein 20", "gene_name": "FAAP20", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BTP7-1", "protein_name": "Fanconi anemia core complex-associated protein 24", "gene_name": "FAAP24", "tax_name": 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"count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Functional characterization of and cooperation between the double-stranded RNA-binding motifs of the protein kinase PKR.", "journal": "The Journal of biological chemistry", "date": "2001-03-30", "authors": "Tian B, Mathews M B", "reference": { "type": "PubMed", "id": "11134010", "url": "https://pubmed.ncbi.nlm.nih.gov/11134010" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O75569-1", "protein_name": "Interferon-inducible double-stranded RNA-dependent protein kinase activator A", "gene_name": "PRKRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y4X5-1", "protein_name": "E3 ubiquitin-protein ligase ARIH1", "gene_name": "ARIH1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15633-1", "protein_name": "RISC-loading complex subunit TARBP2", "gene_name": "TARBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15111-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit alpha", "gene_name": "CHUK", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14933-1", "protein_name": "Ubiquitin/ISG15-conjugating enzyme E2 L6", "gene_name": "UBE2L6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68363-1", "protein_name": "Tubulin alpha-1B chain", "gene_name": "TUBA1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6PEY2-1", "protein_name": "Tubulin alpha-3E chain", "gene_name": "TUBA3E", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68366-1", "protein_name": "Tubulin alpha-4A chain", "gene_name": "TUBA4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q71U36-1", "protein_name": "Tubulin alpha-1A chain", "gene_name": "TUBA1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52564-1", "protein_name": "Dual specificity mitogen-activated protein kinase kinase 6", "gene_name": "MAP2K6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BVA1-1", "protein_name": "Tubulin beta-2B chain", "gene_name": "TUBB2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12905-1", "protein_name": "Interleukin enhancer-binding factor 2", "gene_name": "ILF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2Z9-1", "protein_name": "Centromere protein S", "gene_name": "CENPS-CORT; CENPS", "tax_name": "Human" }, { "uniprot_canonical_ac": "A8MT69-1", "protein_name": "Centromere protein X", "gene_name": "CENPX", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14920-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit beta", "gene_name": "IKBKB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62714-1", "protein_name": "Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform", "gene_name": "PPP2CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14258-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "TRIM25", "tax_name": "Human" }, { "uniprot_canonical_ac": "P34931-1", "protein_name": "Heat shock 70 kDa protein 1-like", "gene_name": "HSPA1L", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54652-1", "protein_name": "Heat shock-related 70 kDa protein 2", "gene_name": "HSPA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20042-1", "protein_name": "Eukaryotic translation initiation factor 2 subunit 2", "gene_name": "EIF2S2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06493-1", "protein_name": "Cyclin-dependent kinase 1", "gene_name": "CDK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYA1-1", "protein_name": "Sphingosine kinase 1", "gene_name": "SPHK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BUF5-1", "protein_name": "Tubulin beta-6 chain", "gene_name": "TUBB6", "tax_name": "Human" }, { "uniprot_canonical_ac": "A6NNZ2-1", "protein_name": "Tubulin beta 8B", "gene_name": "TUBB8B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q3ZCM7-1", "protein_name": "Tubulin beta-8 chain", "gene_name": "TUBB8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04350-1", "protein_name": "Tubulin beta-4A chain", "gene_name": "TUBB4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13885-1", "protein_name": "Tubulin beta-2A chain", "gene_name": "TUBB2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z434-1", "protein_name": "Mitochondrial antiviral-signaling protein", "gene_name": "MAVS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06748-1", "protein_name": "Nucleophosmin", "gene_name": "NPM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11142-1", "protein_name": "Heat shock cognate 71 kDa protein", "gene_name": "HSPA8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NW38-1", "protein_name": "E3 ubiquitin-protein ligase FANCL", "gene_name": "FANCL", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15172-1", "protein_name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform", "gene_name": "PPP2R5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12906-1", "protein_name": "Interleukin enhancer-binding factor 3", "gene_name": "ILF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q08211-1", "protein_name": "ATP-dependent RNA helicase A", "gene_name": "DHX9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05198-1", "protein_name": "Eukaryotic translation initiation factor 2 subunit 1", "gene_name": "EIF2S1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HB96-1", "protein_name": "Fanconi anemia group E protein", "gene_name": "FANCE", "tax_name": "Human" }, { "uniprot_canonical_ac": "P17706-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 2", "gene_name": "PTPN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0DPH8-1", "protein_name": "Tubulin alpha-3D chain", "gene_name": "TUBA3D", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40763-1", "protein_name": "Signal transducer and activator of transcription 3", "gene_name": "STAT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P55265-1", "protein_name": "Double-stranded RNA-specific adenosine deaminase", "gene_name": "ADAR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UII4-1", "protein_name": "E3 ISG15--protein ligase HERC5", "gene_name": "HERC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41091-1", "protein_name": "Eukaryotic translation initiation factor 2 subunit 3", "gene_name": "EIF2S3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NB91-1", "protein_name": "Fanconi anemia group B protein", "gene_name": "FANCB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13509-1", "protein_name": "Tubulin beta-3 chain", "gene_name": "TUBB3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BQE3-1", "protein_name": "Tubulin alpha-1C chain", "gene_name": "TUBA1C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68371-1", "protein_name": "Tubulin beta-4B chain", "gene_name": "TUBB4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H4B7-1", "protein_name": "Tubulin beta-1 chain", "gene_name": "TUBB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H853-1", "protein_name": "Tubulin-like protein alpha-4B", "gene_name": "TUBA4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19525-1", "protein_name": "Interferon-induced, double-stranded RNA-activated protein kinase", "gene_name": "EIF2AK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42224-1", "protein_name": "Signal transducer and activator of transcription 1-alpha/beta", "gene_name": "STAT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NX74-1", "protein_name": "tRNA-dihydrouridine(20) synthase [NAD(P)+]-like", "gene_name": "DUS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13217-1", "protein_name": "DnaJ homolog subfamily C member 3", "gene_name": "DNAJC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15360-1", "protein_name": "Fanconi anemia group A protein", "gene_name": "FANCA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q0VG06-1", "protein_name": "Fanconi anemia core complex-associated protein 100", "gene_name": "FAAP100", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15287-1", "protein_name": "Fanconi anemia group G protein", "gene_name": "FANCG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6NZ36-1", "protein_name": "Fanconi anemia core complex-associated protein 20", "gene_name": "FAAP20", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BTP7-1", "protein_name": "Fanconi anemia core complex-associated protein 24", "gene_name": "FAAP24", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NPI8-1", "protein_name": "Fanconi anemia group F protein", "gene_name": "FANCF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0DMV9-1", "protein_name": "Heat shock 70 kDa protein 1B", "gene_name": "HSPA1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "A6NHL2-1", "protein_name": "Tubulin alpha chain-like 3", "gene_name": "TUBAL3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY65-1", "protein_name": "Tubulin alpha-8 chain", "gene_name": "TUBA8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IYD8-1", "protein_name": "Fanconi anemia group M protein", "gene_name": "FANCM", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05161-1", "protein_name": "Ubiquitin-like protein ISG15", "gene_name": "ISG15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q00597-1", "protein_name": "Fanconi anemia group C protein", "gene_name": "FANCC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0DPH7-1", "protein_name": "Tubulin alpha-3C chain", "gene_name": "TUBA3C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16333-1", "protein_name": "SH2/SH3 adapter protein NCK1", "gene_name": "NCK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6K9-1", "protein_name": "NF-kappa-B essential modulator", "gene_name": "IKBKG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30154-1", "protein_name": "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform", "gene_name": "PPP2R1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0DMV8-1", "protein_name": "Heat shock 70 kDa protein 1A", "gene_name": "HSPA1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30153-1", "protein_name": "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform", "gene_name": "PPP2R1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P67775-1", "protein_name": "Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform", "gene_name": "PPP2CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37840-1", "protein_name": "Alpha-synuclein", "gene_name": "SNCA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04637-1", "protein_name": "Cellular tumor antigen p53", "gene_name": "TP53", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O75569", "url": "https://www.uniprot.org/uniprotkb/O75569" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.11134010", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 75 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ 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