[ { "title": "Identification and preliminary characterization of a protein motif related to the zinc finger.", "journal": "Proc. Natl. Acad. Sci. U.S.A.", "date": "1993", "authors": "Lovering R, Hanson IM, Borden KL, Martin S, O'Reilly NJ, Evan GI, Rahman D, Pappin DJ, Trowsdale J, Freemont PS", "reference": { "type": "PubMed", "id": "7681583", "url": "https://pubmed.ncbi.nlm.nih.gov/7681583" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q06587-1", "protein_name": "E3 ubiquitin-protein ligase RING1", "gene_name": "RING1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q06587", "url": "https://www.uniprot.org/uniprotkb/Q06587" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.7681583", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "RING1 interacts with multiple Polycomb-group proteins and displays tumorigenic activity.", "journal": "Mol. Cell. Biol.", "date": "1999", "authors": "Satijn DP, Otte AP", "reference": { "type": "PubMed", "id": "9858531", "url": "https://pubmed.ncbi.nlm.nih.gov/9858531" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q06587-1", "protein_name": "E3 ubiquitin-protein ligase RING1", "gene_name": "RING1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q06587", "url": "https://www.uniprot.org/uniprotkb/Q06587" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.9858531", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "YTHDF1-CLOCK axis contributes to pathogenesis of allergic airway inflammation through LLPS.", "journal": "Cell reports", "date": "2024-03-26", "authors": "Wang Jing, Zhou Yao, Zhang Meng, Wu Yujiao, Wu Qun, Su Wen, Xu Min, Wu Jinhong, Zhang Min, Shuai Jianwei, Tang Wei, Lv Jiajia, Wu Min, Xia Zhenwei", "reference": { "type": "PubMed", "id": "38492220", "url": "https://pubmed.ncbi.nlm.nih.gov/38492220" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O15516-1", "protein_name": "Circadian locomoter output cycles protein kaput", "gene_name": "CLOCK", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O15516", "url": "https://www.uniprot.org/uniprotkb/O15516" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.38492220", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "CLOCK gene circannual expression in cluster headache.", "journal": "Cephalalgia : an international journal of headache", "date": "2024-04", "authors": "Oliveira Renato, Neves-Costa Ana, Pedroso Dora, Paix\u00e3o Tiago, Barros Andr\u00e9 B, Moita Lu\u00eds F, Gil-Gouveia Raquel", "reference": { "type": "PubMed", "id": "38676534", "url": "https://pubmed.ncbi.nlm.nih.gov/38676534" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O15516-1", "protein_name": "Circadian locomoter output cycles protein kaput", "gene_name": "CLOCK", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O15516", "url": "https://www.uniprot.org/uniprotkb/O15516" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.38676534", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The role of circadian gene CLOCK in cancer.", "journal": "Biochimica et biophysica acta. Molecular cell research", "date": "2024-10", "authors": "Rashed Nasot, Liu Wenbin, Zhou Xinran, Bode Ann M, Luo Xiangjian", "reference": { "type": "PubMed", "id": "38871225", "url": "https://pubmed.ncbi.nlm.nih.gov/38871225" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O15516-1", "protein_name": "Circadian locomoter output cycles protein kaput", "gene_name": "CLOCK", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O15516", "url": "https://www.uniprot.org/uniprotkb/O15516" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.38871225", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Repulsive guidance molecule b inhibits neurite growth and is increased after spinal cord injury.", "journal": "Biochemical and biophysical research communications", "date": "2009", "authors": "Liu X, Hashimoto M, Horii H, Yamaguchi A, Naito K, Yamashita T", "reference": { "type": "PubMed", "id": "19324014", "url": "https://pubmed.ncbi.nlm.nih.gov/19324014" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q6NW40-1", "protein_name": "Repulsive guidance molecule B", "gene_name": "RGMB", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q6NW40", "url": "https://www.uniprot.org/uniprotkb/Q6NW40" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.19324014", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Potential prognostic value of repulsive guidance molecules in breast cancer.", "journal": "Anticancer research", "date": "2011", "authors": "Li J, Ye L, Mansel RE, Jiang WG", "reference": { "type": "PubMed", "id": "21617229", "url": "https://pubmed.ncbi.nlm.nih.gov/21617229" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q6NW40-1", "protein_name": "Repulsive guidance molecule B", "gene_name": "RGMB", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q6NW40", "url": "https://www.uniprot.org/uniprotkb/Q6NW40" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.21617229", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Study on expression of lncRNA RGMB-AS1 and repulsive guidance molecule b in non-small cell lung cancer.", "journal": "Diagnostic pathology", "date": "2015", "authors": "Li P, Li J, Yang R, Zhang F, Wang H, Chu H, Lu Y, Dun S, Wang Y, Zang W, Du Y, Chen X, Zhao G, Zhang G", "reference": { "type": "PubMed", "id": "26055877", "url": "https://pubmed.ncbi.nlm.nih.gov/26055877" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q6NW40-1", "protein_name": "Repulsive guidance molecule B", "gene_name": "RGMB", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q6NW40", "url": "https://www.uniprot.org/uniprotkb/Q6NW40" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.26055877", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Repulsive guidance molecule B inhibits metastasis and is associated with decreased mortality in non-small cell lung cancer.", "journal": "Oncotarget", "date": "2016", "authors": "Li J, Ye L, Shi X, Chen J, Feng F, Chen Y, Xiao Y, Shen J, Li P, Jiang WG, He J", "reference": { "type": "PubMed", "id": "26910889", "url": "https://pubmed.ncbi.nlm.nih.gov/26910889" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q6NW40-1", "protein_name": "Repulsive guidance molecule B", "gene_name": "RGMB", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q6NW40", "url": "https://www.uniprot.org/uniprotkb/Q6NW40" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.26910889", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "RGMB enhances the suppressive activity of the monomeric secreted form of CTLA-4.", "journal": "Scientific reports", "date": "2019", "authors": "Sekiya T, Takaki S", "reference": { "type": "PubMed", "id": "31061392", "url": "https://pubmed.ncbi.nlm.nih.gov/31061392" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q6NW40-1", "protein_name": "Repulsive guidance molecule B", "gene_name": "RGMB", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q6NW40", "url": "https://www.uniprot.org/uniprotkb/Q6NW40" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.31061392", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Repulsive guidance molecules lock growth differentiation factor 5 in an inhibitory complex.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2020", "authors": "Malinauskas T, Peer TV, Bishop B, Mueller TD, Siebold C", "reference": { "type": "PubMed", "id": "32576689", "url": "https://pubmed.ncbi.nlm.nih.gov/32576689" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q6NW40-1", "protein_name": "Repulsive guidance molecule B", "gene_name": "RGMB", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q6NW40", "url": "https://www.uniprot.org/uniprotkb/Q6NW40" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.32576689", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "REDD2 gene is upregulated by modified LDL or hypoxia and mediates human macrophage cell death.", "journal": "Arterioscler. Thromb. Vasc. Biol.", "date": "2004", "authors": "Cuaz-Perolin C, Furman C, Larigauderie G, Legedz L, Lasselin C, Copin C, Jaye M, Searfoss G, Yu KT, Duverger N, Negre-Salvayre A, Fruchart JC, Rouis M", "reference": { "type": "PubMed", "id": "15308555", "url": "https://pubmed.ncbi.nlm.nih.gov/15308555" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q96D03-1", "protein_name": "DNA damage-inducible transcript 4-like protein", "gene_name": "DDIT4L", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q96D03", "url": "https://www.uniprot.org/uniprotkb/Q96D03" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.15308555", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The regulated in development and DNA damage response 2 (REDD2) gene mediates human monocyte cell death through a reduction in thioredoxin-1 expression.", "journal": "Free radical biology & medicine", "date": "2009", "authors": "Imen JS, Billiet L, Cuaz-Perolin C, Michaud N, Rouis M", "reference": { "type": "PubMed", "id": "19268525", "url": "https://pubmed.ncbi.nlm.nih.gov/19268525" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q96D03-1", "protein_name": "DNA damage-inducible transcript 4-like protein", "gene_name": "DDIT4L", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q96D03", "url": "https://www.uniprot.org/uniprotkb/Q96D03" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.19268525", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Megabase chromatin domains involved in DNA double-strand breaks in vivo.", "journal": "The Journal of cell biology", "date": "1999", "authors": "Rogakou EP, Boon C, Redon C, Bonner WM", "reference": { "type": "PubMed", "id": "10477747", "url": "https://pubmed.ncbi.nlm.nih.gov/10477747" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P16104-1", "protein_name": "Histone H2AX", "gene_name": "H2AX", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P16104", "url": "https://www.uniprot.org/uniprotkb/P16104" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 140, "end_pos": 140, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by ATM, ATR and PRKDC", "evidence": [ { "database": "UniProtKB", "id": "P16104", "url": "https://www.uniprot.org/uniprotkb/P16104" }, { "database": "IntAct", "id": "P16104", "url": "https://www.ebi.ac.uk/intact/interactors/id:P16104*" }, { "database": "iPTMnet", "id": "P16104", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16104" }, { "database": "PubMed", "id": "25923214", "url": "https://pubmed.ncbi.nlm.nih.gov/25923214" }, { "database": "PubMed", "id": "22064073", "url": "https://pubmed.ncbi.nlm.nih.gov/22064073" }, { "database": "PubMed", "id": "20118229", "url": "https://pubmed.ncbi.nlm.nih.gov/20118229" }, { "database": "PubMed", "id": "20356835", "url": "https://pubmed.ncbi.nlm.nih.gov/20356835" }, { "database": "PRO", "id": "P16104", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=P16104" }, { "database": "PubMed", "id": "10734083", "url": "https://pubmed.ncbi.nlm.nih.gov/10734083" }, { "database": "PubMed", "id": "10959836", "url": "https://pubmed.ncbi.nlm.nih.gov/10959836" }, { "database": "PubMed", "id": "12660252", "url": "https://pubmed.ncbi.nlm.nih.gov/12660252" }, { "database": "PubMed", "id": "18370922", "url": "https://pubmed.ncbi.nlm.nih.gov/18370922" }, { "database": "PubMed", "id": "12697768", "url": "https://pubmed.ncbi.nlm.nih.gov/12697768" }, { "database": "PubMed", "id": "26124332", "url": "https://pubmed.ncbi.nlm.nih.gov/26124332" }, { "database": "PubMed", "id": "11673449", "url": "https://pubmed.ncbi.nlm.nih.gov/11673449" }, { "database": "PubMed", "id": "12419185", "url": "https://pubmed.ncbi.nlm.nih.gov/12419185" }, { "database": "PubMed", "id": "12607005", "url": "https://pubmed.ncbi.nlm.nih.gov/12607005" }, { "database": "PubMed", "id": "14627815", "url": "https://pubmed.ncbi.nlm.nih.gov/14627815" }, { "database": "PubMed", "id": "15059890", "url": "https://pubmed.ncbi.nlm.nih.gov/15059890" }, { "database": "PubMed", "id": "15489221", "url": "https://pubmed.ncbi.nlm.nih.gov/15489221" }, { "database": "PubMed", "id": "15613478", "url": "https://pubmed.ncbi.nlm.nih.gov/15613478" }, { "database": "PubMed", "id": "17525332", "url": "https://pubmed.ncbi.nlm.nih.gov/17525332" }, { "database": "PubMed", "id": "17709392", "url": "https://pubmed.ncbi.nlm.nih.gov/17709392" }, { "database": "PubMed", "id": "20068231", "url": "https://pubmed.ncbi.nlm.nih.gov/20068231" }, { "database": "PubMed", "id": "21406692", "url": "https://pubmed.ncbi.nlm.nih.gov/21406692" }, { "database": "PubMed", "id": "22154951", "url": "https://pubmed.ncbi.nlm.nih.gov/22154951" }, { "database": "PubMed", "id": "9488723", "url": "https://pubmed.ncbi.nlm.nih.gov/9488723" }, { "database": "PubMed", "id": "10477747", "url": "https://pubmed.ncbi.nlm.nih.gov/10477747" } ], "site_lbl": "Ser140", "uniprot_canonical_ac": "P16104-1" } ], "record_id": "pubmed.10477747", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Initiation of DNA fragmentation during apoptosis induces phosphorylation of H2AX histone at serine 139.", "journal": "The Journal of biological chemistry", "date": "2000", "authors": "Rogakou EP, Nieves-Neira W, Boon C, Pommier Y, Bonner WM", "reference": { "type": "PubMed", "id": "10734083", "url": "https://pubmed.ncbi.nlm.nih.gov/10734083" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P16104-1", "protein_name": "Histone H2AX", "gene_name": "H2AX", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P16104", "url": "https://www.uniprot.org/uniprotkb/P16104" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 140, "end_pos": 140, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by ATM, ATR and PRKDC", "evidence": [ { "database": "UniProtKB", "id": "P16104", "url": "https://www.uniprot.org/uniprotkb/P16104" }, { "database": "IntAct", "id": "P16104", "url": "https://www.ebi.ac.uk/intact/interactors/id:P16104*" }, { "database": "iPTMnet", "id": "P16104", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16104" }, { "database": "PubMed", "id": "25923214", "url": "https://pubmed.ncbi.nlm.nih.gov/25923214" }, { "database": "PubMed", "id": "22064073", "url": "https://pubmed.ncbi.nlm.nih.gov/22064073" }, { "database": "PubMed", "id": "20118229", "url": "https://pubmed.ncbi.nlm.nih.gov/20118229" }, { "database": "PubMed", "id": "20356835", "url": "https://pubmed.ncbi.nlm.nih.gov/20356835" }, { "database": "PRO", "id": "P16104", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=P16104" }, { "database": "PubMed", "id": "10734083", "url": "https://pubmed.ncbi.nlm.nih.gov/10734083" }, { "database": "PubMed", "id": "10959836", "url": "https://pubmed.ncbi.nlm.nih.gov/10959836" }, { "database": "PubMed", "id": "12660252", "url": "https://pubmed.ncbi.nlm.nih.gov/12660252" }, { "database": "PubMed", "id": "18370922", "url": "https://pubmed.ncbi.nlm.nih.gov/18370922" }, { "database": "PubMed", "id": "12697768", "url": "https://pubmed.ncbi.nlm.nih.gov/12697768" }, { "database": "PubMed", "id": "26124332", "url": "https://pubmed.ncbi.nlm.nih.gov/26124332" }, { "database": "PubMed", "id": "11673449", "url": "https://pubmed.ncbi.nlm.nih.gov/11673449" }, { "database": "PubMed", "id": "12419185", "url": "https://pubmed.ncbi.nlm.nih.gov/12419185" }, { "database": "PubMed", "id": "12607005", "url": "https://pubmed.ncbi.nlm.nih.gov/12607005" }, { "database": "PubMed", "id": "14627815", "url": "https://pubmed.ncbi.nlm.nih.gov/14627815" }, { "database": "PubMed", "id": "15059890", "url": "https://pubmed.ncbi.nlm.nih.gov/15059890" }, { "database": "PubMed", "id": "15489221", "url": "https://pubmed.ncbi.nlm.nih.gov/15489221" }, { "database": "PubMed", "id": "15613478", "url": "https://pubmed.ncbi.nlm.nih.gov/15613478" }, { "database": "PubMed", "id": "17525332", "url": "https://pubmed.ncbi.nlm.nih.gov/17525332" }, { "database": "PubMed", "id": "17709392", "url": "https://pubmed.ncbi.nlm.nih.gov/17709392" }, { "database": "PubMed", "id": "20068231", "url": "https://pubmed.ncbi.nlm.nih.gov/20068231" }, { "database": "PubMed", "id": "21406692", "url": "https://pubmed.ncbi.nlm.nih.gov/21406692" }, { "database": "PubMed", "id": "22154951", "url": "https://pubmed.ncbi.nlm.nih.gov/22154951" }, { "database": "PubMed", "id": "9488723", "url": "https://pubmed.ncbi.nlm.nih.gov/9488723" }, { "database": "PubMed", "id": "10477747", "url": "https://pubmed.ncbi.nlm.nih.gov/10477747" } ], "site_lbl": "Ser140", "uniprot_canonical_ac": "P16104-1" } ], "record_id": "pubmed.10734083", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Doxorubicin activates ATM-dependent phosphorylation of multiple downstream targets in part through the generation of reactive oxygen species.", "journal": "The Journal of biological chemistry", "date": "2004", "authors": "Kurz EU, Douglas P, Lees-Miller SP", "reference": { "type": "PubMed", "id": "15489221", "url": "https://pubmed.ncbi.nlm.nih.gov/15489221" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P16104-1", "protein_name": "Histone H2AX", "gene_name": "H2AX", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13315-1", "protein_name": "Serine-protein kinase ATM", "gene_name": "ATM", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P16104", "url": "https://www.uniprot.org/uniprotkb/P16104" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 140, "end_pos": 140, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by ATM, ATR and PRKDC", "evidence": [ { "database": "UniProtKB", "id": "P16104", "url": "https://www.uniprot.org/uniprotkb/P16104" }, { "database": "IntAct", "id": "P16104", "url": "https://www.ebi.ac.uk/intact/interactors/id:P16104*" }, { "database": "iPTMnet", "id": "P16104", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16104" }, { "database": "PubMed", "id": "25923214", "url": "https://pubmed.ncbi.nlm.nih.gov/25923214" }, { "database": "PubMed", "id": "22064073", "url": "https://pubmed.ncbi.nlm.nih.gov/22064073" }, { "database": "PubMed", "id": "20118229", "url": "https://pubmed.ncbi.nlm.nih.gov/20118229" }, { "database": "PubMed", "id": "20356835", "url": "https://pubmed.ncbi.nlm.nih.gov/20356835" }, { "database": "PRO", "id": "P16104", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=P16104" }, { "database": "PubMed", "id": "10734083", "url": "https://pubmed.ncbi.nlm.nih.gov/10734083" }, { "database": "PubMed", "id": "10959836", "url": "https://pubmed.ncbi.nlm.nih.gov/10959836" }, { "database": "PubMed", "id": "12660252", "url": "https://pubmed.ncbi.nlm.nih.gov/12660252" }, { "database": "PubMed", "id": "18370922", "url": "https://pubmed.ncbi.nlm.nih.gov/18370922" }, { "database": "PubMed", "id": "12697768", "url": "https://pubmed.ncbi.nlm.nih.gov/12697768" }, { "database": "PubMed", "id": "26124332", "url": "https://pubmed.ncbi.nlm.nih.gov/26124332" }, { "database": "PubMed", "id": "11673449", "url": "https://pubmed.ncbi.nlm.nih.gov/11673449" }, { "database": "PubMed", "id": "12419185", "url": "https://pubmed.ncbi.nlm.nih.gov/12419185" }, { "database": "PubMed", "id": "12607005", "url": "https://pubmed.ncbi.nlm.nih.gov/12607005" }, { "database": "PubMed", "id": "14627815", "url": "https://pubmed.ncbi.nlm.nih.gov/14627815" }, { "database": "PubMed", "id": "15059890", "url": "https://pubmed.ncbi.nlm.nih.gov/15059890" }, { "database": "PubMed", "id": "15489221", "url": "https://pubmed.ncbi.nlm.nih.gov/15489221" }, { "database": "PubMed", "id": "15613478", "url": "https://pubmed.ncbi.nlm.nih.gov/15613478" }, { "database": "PubMed", "id": "17525332", "url": "https://pubmed.ncbi.nlm.nih.gov/17525332" }, { "database": "PubMed", "id": "17709392", "url": "https://pubmed.ncbi.nlm.nih.gov/17709392" }, { "database": "PubMed", "id": "20068231", "url": "https://pubmed.ncbi.nlm.nih.gov/20068231" }, { "database": "PubMed", "id": "21406692", "url": "https://pubmed.ncbi.nlm.nih.gov/21406692" }, { "database": "PubMed", "id": "22154951", "url": "https://pubmed.ncbi.nlm.nih.gov/22154951" }, { "database": "PubMed", "id": "9488723", "url": "https://pubmed.ncbi.nlm.nih.gov/9488723" }, { "database": "PubMed", "id": "10477747", "url": "https://pubmed.ncbi.nlm.nih.gov/10477747" } ], "site_lbl": "Ser140", "uniprot_canonical_ac": "P16104-1" }, { "start_pos": 1981, "end_pos": 1981, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by autocatalysis", "evidence": [ { "database": "UniProtKB", "id": "Q13315", "url": "https://www.uniprot.org/uniprotkb/Q13315" }, { "database": "IntAct", "id": "Q13315", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q13315*" }, { "database": "iPTMnet", "id": "Q13315", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q13315" }, { "database": "PubMed", "id": "19851285", "url": "https://pubmed.ncbi.nlm.nih.gov/19851285" }, { "database": "PubMed", "id": "16858402", "url": "https://pubmed.ncbi.nlm.nih.gov/16858402" }, { "database": "PRO", "id": "Q13315", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=Q13315" }, { "database": "PubMed", "id": "22099307", "url": "https://pubmed.ncbi.nlm.nih.gov/22099307" }, { "database": "PubMed", "id": "12556884", "url": "https://pubmed.ncbi.nlm.nih.gov/12556884" }, { "database": "PubMed", "id": "14695167", "url": "https://pubmed.ncbi.nlm.nih.gov/14695167" }, { "database": "PubMed", "id": "14871926", "url": "https://pubmed.ncbi.nlm.nih.gov/14871926" }, { "database": "PubMed", "id": "15048089", "url": "https://pubmed.ncbi.nlm.nih.gov/15048089" }, { "database": "PubMed", "id": "15140942", "url": "https://pubmed.ncbi.nlm.nih.gov/15140942" }, { "database": "PubMed", "id": "15177039", "url": "https://pubmed.ncbi.nlm.nih.gov/15177039" }, { "database": "PubMed", "id": "15177184", "url": "https://pubmed.ncbi.nlm.nih.gov/15177184" }, { "database": "PubMed", "id": "15269203", "url": "https://pubmed.ncbi.nlm.nih.gov/15269203" }, { "database": "PubMed", "id": "15313175", "url": "https://pubmed.ncbi.nlm.nih.gov/15313175" }, { "database": "PubMed", "id": "15314656", "url": "https://pubmed.ncbi.nlm.nih.gov/15314656" }, { "database": "PubMed", "id": "15489221", "url": "https://pubmed.ncbi.nlm.nih.gov/15489221" }, { "database": "PubMed", "id": "15510216", "url": "https://pubmed.ncbi.nlm.nih.gov/15510216" }, { "database": "PubMed", "id": "15846060", "url": "https://pubmed.ncbi.nlm.nih.gov/15846060" }, { "database": "PubMed", "id": "16293623", "url": "https://pubmed.ncbi.nlm.nih.gov/16293623" }, { "database": "PubMed", "id": "16319535", "url": "https://pubmed.ncbi.nlm.nih.gov/16319535" }, { "database": "PubMed", "id": "16452482", "url": "https://pubmed.ncbi.nlm.nih.gov/16452482" }, { "database": "PubMed", "id": "16528719", "url": "https://pubmed.ncbi.nlm.nih.gov/16528719" }, { "database": "PubMed", "id": "16533058", "url": "https://pubmed.ncbi.nlm.nih.gov/16533058" }, { "database": "PubMed", "id": "16556909", "url": "https://pubmed.ncbi.nlm.nih.gov/16556909" }, { "database": "PubMed", "id": "16628011", "url": "https://pubmed.ncbi.nlm.nih.gov/16628011" }, { "database": "PubMed", "id": "16636671", "url": "https://pubmed.ncbi.nlm.nih.gov/16636671" }, { "database": "PubMed", "id": "16861926", "url": "https://pubmed.ncbi.nlm.nih.gov/16861926" }, { "database": "PubMed", "id": "16906133", "url": "https://pubmed.ncbi.nlm.nih.gov/16906133" }, { "database": "PubMed", "id": "16940754", "url": "https://pubmed.ncbi.nlm.nih.gov/16940754" }, { "database": "PubMed", "id": "16997395", "url": "https://pubmed.ncbi.nlm.nih.gov/16997395" }, { "database": "PubMed", "id": "17016017", "url": "https://pubmed.ncbi.nlm.nih.gov/17016017" }, { "database": "PubMed", "id": "17124492", "url": "https://pubmed.ncbi.nlm.nih.gov/17124492" }, { "database": "PubMed", "id": "17406032", "url": "https://pubmed.ncbi.nlm.nih.gov/17406032" }, { "database": "PubMed", "id": "17486112", "url": "https://pubmed.ncbi.nlm.nih.gov/17486112" }, { "database": "PubMed", "id": "17638905", "url": "https://pubmed.ncbi.nlm.nih.gov/17638905" }, { "database": "PubMed", "id": "17700524", "url": "https://pubmed.ncbi.nlm.nih.gov/17700524" }, { "database": "PubMed", "id": "18048416", "url": "https://pubmed.ncbi.nlm.nih.gov/18048416" }, { "database": "PubMed", "id": "18059176", "url": "https://pubmed.ncbi.nlm.nih.gov/18059176" }, { "database": "PubMed", "id": "18248856", "url": "https://pubmed.ncbi.nlm.nih.gov/18248856" }, { "database": "PubMed", "id": "18344987", "url": "https://pubmed.ncbi.nlm.nih.gov/18344987" }, { "database": "PubMed", "id": "18431490", "url": "https://pubmed.ncbi.nlm.nih.gov/18431490" }, { "database": "PubMed", "id": "18560558", "url": "https://pubmed.ncbi.nlm.nih.gov/18560558" }, { "database": "PubMed", "id": "18571408", "url": "https://pubmed.ncbi.nlm.nih.gov/18571408" }, { "database": "PubMed", "id": "18593910", "url": "https://pubmed.ncbi.nlm.nih.gov/18593910" }, { "database": "PubMed", "id": "18596698", "url": "https://pubmed.ncbi.nlm.nih.gov/18596698" }, { "database": "PubMed", "id": "18619531", "url": "https://pubmed.ncbi.nlm.nih.gov/18619531" }, { "database": "PubMed", "id": "18663430", "url": "https://pubmed.ncbi.nlm.nih.gov/18663430" }, { "database": "PubMed", "id": "18762365", "url": "https://pubmed.ncbi.nlm.nih.gov/18762365" }, { "database": "PubMed", "id": "18959818", "url": "https://pubmed.ncbi.nlm.nih.gov/18959818" }, { "database": "PubMed", "id": "18985806", "url": "https://pubmed.ncbi.nlm.nih.gov/18985806" }, { "database": "PubMed", "id": "19401701", "url": "https://pubmed.ncbi.nlm.nih.gov/19401701" }, { "database": "PubMed", "id": "19411853", "url": "https://pubmed.ncbi.nlm.nih.gov/19411853" }, { "database": "PubMed", "id": "19451263", "url": "https://pubmed.ncbi.nlm.nih.gov/19451263" }, { "database": "PubMed", "id": "19605351", "url": "https://pubmed.ncbi.nlm.nih.gov/19605351" }, { "database": "PubMed", "id": "19621083", "url": "https://pubmed.ncbi.nlm.nih.gov/19621083" }, { "database": "PubMed", "id": "19625493", "url": "https://pubmed.ncbi.nlm.nih.gov/19625493" }, { "database": "PubMed", "id": "19658174", "url": "https://pubmed.ncbi.nlm.nih.gov/19658174" }, { "database": "PubMed", "id": "19671522", "url": "https://pubmed.ncbi.nlm.nih.gov/19671522" }, { "database": "PubMed", "id": "19744477", "url": "https://pubmed.ncbi.nlm.nih.gov/19744477" }, { "database": "PubMed", "id": "19798429", "url": "https://pubmed.ncbi.nlm.nih.gov/19798429" }, { "database": "PubMed", "id": "20014310", "url": "https://pubmed.ncbi.nlm.nih.gov/20014310" }, { "database": "PubMed", "id": "20126263", "url": "https://pubmed.ncbi.nlm.nih.gov/20126263" }, { "database": "PubMed", "id": "20205745", "url": "https://pubmed.ncbi.nlm.nih.gov/20205745" }, { "database": "PubMed", "id": "20660628", "url": "https://pubmed.ncbi.nlm.nih.gov/20660628" }, { "database": "PubMed", "id": "20678255", "url": "https://pubmed.ncbi.nlm.nih.gov/20678255" }, { "database": "PubMed", "id": "20700484", "url": "https://pubmed.ncbi.nlm.nih.gov/20700484" }, { "database": "PubMed", "id": "20711462", "url": "https://pubmed.ncbi.nlm.nih.gov/20711462" }, { "database": "PubMed", "id": "20959117", "url": "https://pubmed.ncbi.nlm.nih.gov/20959117" }, { "database": "PubMed", "id": "20976220", "url": "https://pubmed.ncbi.nlm.nih.gov/20976220" }, { "database": "PubMed", "id": "20978201", "url": "https://pubmed.ncbi.nlm.nih.gov/20978201" }, { "database": "PubMed", "id": "21078189", "url": "https://pubmed.ncbi.nlm.nih.gov/21078189" }, { "database": "PubMed", "id": "21157431", "url": "https://pubmed.ncbi.nlm.nih.gov/21157431" }, { "database": "PubMed", "id": "21219611", "url": "https://pubmed.ncbi.nlm.nih.gov/21219611" }, { "database": "PubMed", "id": "21292467", "url": "https://pubmed.ncbi.nlm.nih.gov/21292467" }, { "database": "PubMed", "id": "21338495", "url": "https://pubmed.ncbi.nlm.nih.gov/21338495" }, { "database": "PubMed", "id": "21390062", "url": "https://pubmed.ncbi.nlm.nih.gov/21390062" }, { "database": "PubMed", "id": "21573174", "url": "https://pubmed.ncbi.nlm.nih.gov/21573174" }, { "database": "PubMed", "id": "21824286", "url": "https://pubmed.ncbi.nlm.nih.gov/21824286" }, { "database": "PubMed", "id": "21997193", "url": "https://pubmed.ncbi.nlm.nih.gov/21997193" }, { "database": "PubMed", "id": "22323184", "url": "https://pubmed.ncbi.nlm.nih.gov/22323184" }, { "database": "PubMed", "id": "22416035", "url": "https://pubmed.ncbi.nlm.nih.gov/22416035" }, { "database": "PubMed", "id": "22493319", "url": "https://pubmed.ncbi.nlm.nih.gov/22493319" }, { "database": "PubMed", "id": "22498490", "url": "https://pubmed.ncbi.nlm.nih.gov/22498490" }, { "database": "PubMed", "id": "22655027", "url": "https://pubmed.ncbi.nlm.nih.gov/22655027" }, { "database": "PubMed", "id": "22739265", "url": "https://pubmed.ncbi.nlm.nih.gov/22739265" }, { "database": "PubMed", "id": "22761798", "url": "https://pubmed.ncbi.nlm.nih.gov/22761798" }, { "database": "PubMed", "id": "22837425", "url": "https://pubmed.ncbi.nlm.nih.gov/22837425" }, { "database": "PubMed", "id": "22841545", "url": "https://pubmed.ncbi.nlm.nih.gov/22841545" }, { "database": "PubMed", "id": "22952040", "url": "https://pubmed.ncbi.nlm.nih.gov/22952040" }, { "database": "PubMed", "id": "23146902", "url": "https://pubmed.ncbi.nlm.nih.gov/23146902" }, { "database": "PubMed", "id": "23166842", "url": "https://pubmed.ncbi.nlm.nih.gov/23166842" }, { "database": "PubMed", "id": "23185347", "url": "https://pubmed.ncbi.nlm.nih.gov/23185347" }, { "database": "PubMed", "id": "23193277", "url": "https://pubmed.ncbi.nlm.nih.gov/23193277" }, { "database": "PubMed", "id": "23365634", "url": "https://pubmed.ncbi.nlm.nih.gov/23365634" }, { "database": "PubMed", "id": "23383259", "url": "https://pubmed.ncbi.nlm.nih.gov/23383259" }, { "database": "PubMed", "id": "23533526", "url": "https://pubmed.ncbi.nlm.nih.gov/23533526" }, { "database": "PubMed", "id": "23552604", "url": "https://pubmed.ncbi.nlm.nih.gov/23552604" }, { "database": "PubMed", "id": "23620287", "url": "https://pubmed.ncbi.nlm.nih.gov/23620287" }, { "database": "PubMed", "id": "23666059", "url": "https://pubmed.ncbi.nlm.nih.gov/23666059" }, { "database": "PubMed", "id": "23705030", "url": "https://pubmed.ncbi.nlm.nih.gov/23705030" }, { "database": "PubMed", "id": "23900392", "url": "https://pubmed.ncbi.nlm.nih.gov/23900392" }, { "database": "PubMed", "id": "24086335", "url": "https://pubmed.ncbi.nlm.nih.gov/24086335" }, { "database": "PubMed", "id": "24113180", "url": "https://pubmed.ncbi.nlm.nih.gov/24113180" }, { "database": "PubMed", "id": "24268576", "url": "https://pubmed.ncbi.nlm.nih.gov/24268576" }, { "database": "PubMed", "id": "24280901", "url": "https://pubmed.ncbi.nlm.nih.gov/24280901" }, { "database": "PubMed", "id": "24505404", "url": "https://pubmed.ncbi.nlm.nih.gov/24505404" }, { "database": "PubMed", "id": "24763056", "url": "https://pubmed.ncbi.nlm.nih.gov/24763056" }, { "database": "PubMed", "id": "24812435", "url": "https://pubmed.ncbi.nlm.nih.gov/24812435" }, { "database": "PubMed", "id": "24933654", "url": "https://pubmed.ncbi.nlm.nih.gov/24933654" }, { "database": "PubMed", "id": "24988892", "url": "https://pubmed.ncbi.nlm.nih.gov/24988892" }, { "database": "PubMed", "id": "25003995", "url": "https://pubmed.ncbi.nlm.nih.gov/25003995" }, { "database": "PubMed", "id": "25077176", "url": "https://pubmed.ncbi.nlm.nih.gov/25077176" }, { "database": "PubMed", "id": "25088203", "url": "https://pubmed.ncbi.nlm.nih.gov/25088203" }, { "database": "PubMed", "id": "25111195", "url": "https://pubmed.ncbi.nlm.nih.gov/25111195" }, { "database": "PubMed", "id": "25240135", "url": "https://pubmed.ncbi.nlm.nih.gov/25240135" }, { "database": "PubMed", "id": "25527123", "url": "https://pubmed.ncbi.nlm.nih.gov/25527123" }, { "database": "PubMed", "id": "25611382", "url": "https://pubmed.ncbi.nlm.nih.gov/25611382" }, { "database": "PubMed", "id": "25821946", "url": "https://pubmed.ncbi.nlm.nih.gov/25821946" }, { "database": "PubMed", "id": "25826455", "url": "https://pubmed.ncbi.nlm.nih.gov/25826455" }, { "database": "PubMed", "id": "25865756", "url": "https://pubmed.ncbi.nlm.nih.gov/25865756" }, { "database": "PubMed", "id": "25904696", "url": "https://pubmed.ncbi.nlm.nih.gov/25904696" }, { "database": "PubMed", "id": "25923214", "url": "https://pubmed.ncbi.nlm.nih.gov/25923214" }, { "database": "PubMed", "id": "25977998", "url": "https://pubmed.ncbi.nlm.nih.gov/25977998" }, { "database": "PubMed", "id": "26158765", "url": "https://pubmed.ncbi.nlm.nih.gov/26158765" }, { "database": "PubMed", "id": "26240375", "url": "https://pubmed.ncbi.nlm.nih.gov/26240375" }, { "database": "PubMed", "id": "26275218", "url": "https://pubmed.ncbi.nlm.nih.gov/26275218" }, { "database": "PubMed", "id": "26416514", "url": "https://pubmed.ncbi.nlm.nih.gov/26416514" }, { "database": "PubMed", "id": "26427042", "url": "https://pubmed.ncbi.nlm.nih.gov/26427042" }, { "database": "PubMed", "id": "26431963", "url": "https://pubmed.ncbi.nlm.nih.gov/26431963" }, { "database": "PubMed", "id": "26438152", "url": "https://pubmed.ncbi.nlm.nih.gov/26438152" }, { "database": "PubMed", "id": "26517194", "url": "https://pubmed.ncbi.nlm.nih.gov/26517194" }, { "database": "PubMed", "id": "26517239", "url": "https://pubmed.ncbi.nlm.nih.gov/26517239" }, { "database": "PubMed", "id": "26556501", "url": "https://pubmed.ncbi.nlm.nih.gov/26556501" }, { "database": "PubMed", "id": "26677768", "url": "https://pubmed.ncbi.nlm.nih.gov/26677768" }, { "database": "PubMed", "id": "26683224", "url": "https://pubmed.ncbi.nlm.nih.gov/26683224" }, { "database": "PubMed", "id": "26751069", "url": "https://pubmed.ncbi.nlm.nih.gov/26751069" }, { "database": "PubMed", "id": "26824362", "url": "https://pubmed.ncbi.nlm.nih.gov/26824362" }, { "database": "PubMed", "id": "26860083", "url": "https://pubmed.ncbi.nlm.nih.gov/26860083" }, { "database": "PubMed", "id": "26875667", "url": "https://pubmed.ncbi.nlm.nih.gov/26875667" }, { "database": "PubMed", "id": "26919204", "url": "https://pubmed.ncbi.nlm.nih.gov/26919204" }, { "database": "PubMed", "id": "27029031", "url": "https://pubmed.ncbi.nlm.nih.gov/27029031" }, { "database": "PubMed", "id": "27089984", "url": "https://pubmed.ncbi.nlm.nih.gov/27089984" }, { "database": "PubMed", "id": "27097159", "url": "https://pubmed.ncbi.nlm.nih.gov/27097159" }, { "database": "PubMed", "id": "27258787", "url": "https://pubmed.ncbi.nlm.nih.gov/27258787" }, { "database": "PubMed", "id": "27259260", "url": "https://pubmed.ncbi.nlm.nih.gov/27259260" }, { "database": "PubMed", "id": "27273218", "url": "https://pubmed.ncbi.nlm.nih.gov/27273218" }, { "database": "PubMed", "id": "27391441", "url": "https://pubmed.ncbi.nlm.nih.gov/27391441" }, { "database": "PubMed", "id": "27462418", "url": "https://pubmed.ncbi.nlm.nih.gov/27462418" }, { "database": "PubMed", "id": "27468685", "url": "https://pubmed.ncbi.nlm.nih.gov/27468685" }, { "database": "PubMed", "id": "27524627", "url": "https://pubmed.ncbi.nlm.nih.gov/27524627" }, { "database": "PubMed", "id": "27602502", "url": "https://pubmed.ncbi.nlm.nih.gov/27602502" }, { "database": "PubMed", "id": "27603133", "url": "https://pubmed.ncbi.nlm.nih.gov/27603133" }, { "database": "PubMed", "id": "27613518", "url": "https://pubmed.ncbi.nlm.nih.gov/27613518" }, { "database": "PubMed", "id": "27705915", "url": "https://pubmed.ncbi.nlm.nih.gov/27705915" }, { "database": "PubMed", "id": "27907109", "url": "https://pubmed.ncbi.nlm.nih.gov/27907109" }, { "database": "PubMed", "id": "27959319", "url": "https://pubmed.ncbi.nlm.nih.gov/27959319" }, { "database": "PubMed", "id": "28182994", "url": "https://pubmed.ncbi.nlm.nih.gov/28182994" }, { "database": "PubMed", "id": "28202068", "url": "https://pubmed.ncbi.nlm.nih.gov/28202068" }, { "database": "PubMed", "id": "28250390", "url": "https://pubmed.ncbi.nlm.nih.gov/28250390" }, { "database": "PubMed", "id": "28259977", "url": "https://pubmed.ncbi.nlm.nih.gov/28259977" }, { "database": "PubMed", "id": "28387728", "url": "https://pubmed.ncbi.nlm.nih.gov/28387728" }, { "database": "PubMed", "id": "28412751", "url": "https://pubmed.ncbi.nlm.nih.gov/28412751" }, { "database": "PubMed", "id": "28477111", "url": "https://pubmed.ncbi.nlm.nih.gov/28477111" }, { "database": "PubMed", "id": "28477132", "url": "https://pubmed.ncbi.nlm.nih.gov/28477132" }, { "database": "PubMed", "id": "28648892", "url": "https://pubmed.ncbi.nlm.nih.gov/28648892" }, { "database": "PubMed", "id": "28881600", "url": "https://pubmed.ncbi.nlm.nih.gov/28881600" }, { "database": "PubMed", "id": "28973009", "url": "https://pubmed.ncbi.nlm.nih.gov/28973009" }, { "database": "PubMed", "id": "29048667", "url": "https://pubmed.ncbi.nlm.nih.gov/29048667" }, { "database": "PubMed", "id": "29088817", "url": "https://pubmed.ncbi.nlm.nih.gov/29088817" }, { "database": "PubMed", "id": "29147215", "url": "https://pubmed.ncbi.nlm.nih.gov/29147215" }, { "database": "PubMed", "id": "29294106", "url": "https://pubmed.ncbi.nlm.nih.gov/29294106" }, { "database": "PubMed", "id": "29399146", "url": "https://pubmed.ncbi.nlm.nih.gov/29399146" }, { "database": "PubMed", "id": "29540829", "url": "https://pubmed.ncbi.nlm.nih.gov/29540829" }, { "database": "PubMed", "id": "29615613", "url": "https://pubmed.ncbi.nlm.nih.gov/29615613" }, { "database": "PubMed", "id": "30088201", "url": "https://pubmed.ncbi.nlm.nih.gov/30088201" }, { "database": "PubMed", "id": "30237520", "url": "https://pubmed.ncbi.nlm.nih.gov/30237520" }, { "database": "PubMed", "id": "30245854", "url": "https://pubmed.ncbi.nlm.nih.gov/30245854" }, { "database": "PubMed", "id": "30258062", "url": "https://pubmed.ncbi.nlm.nih.gov/30258062" }, { "database": "PubMed", "id": "30297868", "url": "https://pubmed.ncbi.nlm.nih.gov/30297868" }, { "database": "PubMed", "id": "30473536", "url": "https://pubmed.ncbi.nlm.nih.gov/30473536" }, { "database": "PubMed", "id": "30565836", "url": "https://pubmed.ncbi.nlm.nih.gov/30565836" }, { "database": "PubMed", "id": "30577494", "url": "https://pubmed.ncbi.nlm.nih.gov/30577494" }, { "database": "PubMed", "id": "30679601", "url": "https://pubmed.ncbi.nlm.nih.gov/30679601" }, { "database": "PubMed", "id": "30783677", "url": "https://pubmed.ncbi.nlm.nih.gov/30783677" }, { "database": "PubMed", "id": "30886146", "url": "https://pubmed.ncbi.nlm.nih.gov/30886146" }, { "database": "PubMed", "id": "30943920", "url": "https://pubmed.ncbi.nlm.nih.gov/30943920" }, { "database": "PubMed", "id": "30967632", "url": "https://pubmed.ncbi.nlm.nih.gov/30967632" }, { "database": "PubMed", "id": "31114877", "url": "https://pubmed.ncbi.nlm.nih.gov/31114877" }, { "database": "PubMed", "id": "31164689", "url": "https://pubmed.ncbi.nlm.nih.gov/31164689" }, { "database": "PubMed", "id": "31307507", "url": "https://pubmed.ncbi.nlm.nih.gov/31307507" }, { "database": "PubMed", "id": "31372798", "url": "https://pubmed.ncbi.nlm.nih.gov/31372798" }, { "database": "PubMed", "id": "31481733", "url": "https://pubmed.ncbi.nlm.nih.gov/31481733" }, { "database": "PubMed", "id": "31759252", "url": "https://pubmed.ncbi.nlm.nih.gov/31759252" }, { "database": "PubMed", "id": "31805725", "url": "https://pubmed.ncbi.nlm.nih.gov/31805725" }, { "database": "PubMed", "id": "31827702", "url": "https://pubmed.ncbi.nlm.nih.gov/31827702" }, { "database": "PubMed", "id": "31857852", "url": "https://pubmed.ncbi.nlm.nih.gov/31857852" }, { "database": "PubMed", "id": "32015321", "url": "https://pubmed.ncbi.nlm.nih.gov/32015321" }, { "database": "PubMed", "id": "32059363", "url": "https://pubmed.ncbi.nlm.nih.gov/32059363" }, { "database": "PubMed", "id": "32203529", "url": "https://pubmed.ncbi.nlm.nih.gov/32203529" }, { "database": "PubMed", "id": "32226530", "url": "https://pubmed.ncbi.nlm.nih.gov/32226530" }, { "database": "PubMed", "id": "32377397", "url": "https://pubmed.ncbi.nlm.nih.gov/32377397" }, { "database": "PubMed", "id": "32444694", "url": "https://pubmed.ncbi.nlm.nih.gov/32444694" }, { "database": "PubMed", "id": "32479542", "url": "https://pubmed.ncbi.nlm.nih.gov/32479542" }, { "database": "PubMed", "id": "32665601", "url": "https://pubmed.ncbi.nlm.nih.gov/32665601" }, { "database": "PubMed", "id": "32752095", "url": "https://pubmed.ncbi.nlm.nih.gov/32752095" }, { "database": "PubMed", "id": "32879366", "url": "https://pubmed.ncbi.nlm.nih.gov/32879366" }, { "database": "PubMed", "id": "33024871", "url": "https://pubmed.ncbi.nlm.nih.gov/33024871" }, { "database": "PubMed", "id": "33039867", "url": "https://pubmed.ncbi.nlm.nih.gov/33039867" }, { "database": "PubMed", "id": "33096336", "url": "https://pubmed.ncbi.nlm.nih.gov/33096336" }, { "database": "PubMed", "id": "33245190", "url": "https://pubmed.ncbi.nlm.nih.gov/33245190" }, { "database": "PubMed", "id": "33437944", "url": "https://pubmed.ncbi.nlm.nih.gov/33437944" }, { "database": "PubMed", "id": "33628174", "url": "https://pubmed.ncbi.nlm.nih.gov/33628174" }, { "database": "PubMed", "id": "33802884", "url": "https://pubmed.ncbi.nlm.nih.gov/33802884" }, { "database": "PubMed", "id": "16141325", "url": "https://pubmed.ncbi.nlm.nih.gov/16141325" }, { "database": "PubMed", "id": "17525332", "url": "https://pubmed.ncbi.nlm.nih.gov/17525332" }, { "database": "PubMed", "id": "21144835", "url": "https://pubmed.ncbi.nlm.nih.gov/21144835" }, { "database": "PubMed", "id": "30944854", "url": "https://pubmed.ncbi.nlm.nih.gov/30944854" } ], "site_lbl": "Ser1981", "uniprot_canonical_ac": "Q13315-1" } ], "record_id": "pubmed.15489221", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "gamma-H2AX dephosphorylation by protein phosphatase 2A facilitates DNA double-strand break repair.", "journal": "Mol. Cell", "date": "2005", "authors": "Chowdhury Dipanjan, Keogh Michael-Christopher, Ishii Haruhiko, Peterson Craig L, Buratowski Stephen, Lieberman Judy", "reference": { "type": "PubMed", "id": "16310392", "url": "https://pubmed.ncbi.nlm.nih.gov/16310392" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P16104-1", "protein_name": "Histone H2AX", "gene_name": "H2AX", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P16104", "url": "https://www.uniprot.org/uniprotkb/P16104" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.16310392", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Cell apoptosis: requirement of H2AX in DNA ladder formation, but not for the activation of caspase-3.", "journal": "Molecular cell", "date": "2006", "authors": "Lu C, Zhu F, Cho YY, Tang F, Zykova T, Ma WY, Bode AM, Dong Z", "reference": { "type": "PubMed", "id": "16818236", "url": "https://pubmed.ncbi.nlm.nih.gov/16818236" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P16104-1", "protein_name": "Histone H2AX", "gene_name": "H2AX", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P16104", "url": "https://www.uniprot.org/uniprotkb/P16104" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 140, "end_pos": 140, "kinase_uniprot_canonical_ac": "P45983-1", "kinase_gene_name": "MAPK8", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P16104", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16104" }, { "database": "PubMed", "id": "16818236", "url": "https://pubmed.ncbi.nlm.nih.gov/16818236" }, { "database": "PubMed", "id": "19234442", "url": "https://pubmed.ncbi.nlm.nih.gov/19234442" } ], "site_lbl": "Ser140", "uniprot_canonical_ac": "P16104-1" }, { "start_pos": 140, "end_pos": 140, "kinase_uniprot_canonical_ac": "P45984-1", "kinase_gene_name": "MAPK9", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P16104", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16104" }, { "database": "PubMed", "id": "16818236", "url": "https://pubmed.ncbi.nlm.nih.gov/16818236" }, { "database": "PubMed", "id": "18158901", "url": "https://pubmed.ncbi.nlm.nih.gov/18158901" } ], "site_lbl": "Ser140", "uniprot_canonical_ac": "P16104-1" } ], "record_id": "pubmed.16818236", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Distinct roles of chromatin-associated proteins MDC1 and 53BP1 in mammalian double-strand break repair.", "journal": "Molecular cell", "date": "2007", "authors": "Xie A, Hartlerode A, Stucki M, Odate S, Puget N, Kwok A, Nagaraju G, Yan C, Alt FW, Chen J, Jackson SP, Scully R", "reference": { "type": "PubMed", "id": "18158901", "url": "https://pubmed.ncbi.nlm.nih.gov/18158901" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P16104-1", "protein_name": "Histone H2AX", "gene_name": "H2AX", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P16104", "url": "https://www.uniprot.org/uniprotkb/P16104" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 140, "end_pos": 140, "kinase_uniprot_canonical_ac": "P45984-1", "kinase_gene_name": "MAPK9", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P16104", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16104" }, { "database": "PubMed", "id": "16818236", "url": "https://pubmed.ncbi.nlm.nih.gov/16818236" }, { "database": "PubMed", "id": "18158901", "url": "https://pubmed.ncbi.nlm.nih.gov/18158901" } ], "site_lbl": "Ser140", "uniprot_canonical_ac": "P16104-1" }, { "start_pos": 140, "end_pos": 140, "kinase_uniprot_canonical_ac": "Q13315-1", "kinase_gene_name": "ATM", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P16104", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16104" }, { "database": "PubMed", "id": "11571274", "url": "https://pubmed.ncbi.nlm.nih.gov/11571274" }, { "database": "PubMed", "id": "11893489", "url": "https://pubmed.ncbi.nlm.nih.gov/11893489" }, { "database": "PubMed", "id": "20068231", "url": "https://pubmed.ncbi.nlm.nih.gov/20068231" }, { "database": "PubMed", "id": "9488723", "url": "https://pubmed.ncbi.nlm.nih.gov/9488723" }, { "database": "PubMed", "id": "18158901", "url": "https://pubmed.ncbi.nlm.nih.gov/18158901" }, { "database": "PubMed", "id": "21690091", "url": "https://pubmed.ncbi.nlm.nih.gov/21690091" } ], "site_lbl": "Ser140", "uniprot_canonical_ac": "P16104-1" } ], "record_id": "pubmed.18158901", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Mechanism and regulation of class switch recombination.", "journal": "Annual review of immunology", "date": "2008", "authors": "Stavnezer J, Guikema JE, Schrader CE", "reference": { "type": "PubMed", "id": "18370922", "url": "https://pubmed.ncbi.nlm.nih.gov/18370922" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P16104-1", "protein_name": "Histone H2AX", "gene_name": "H2AX", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P16104", "url": "https://www.uniprot.org/uniprotkb/P16104" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 140, "end_pos": 140, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by ATM, ATR and PRKDC", "evidence": [ { "database": "UniProtKB", "id": "P16104", "url": "https://www.uniprot.org/uniprotkb/P16104" }, { "database": "IntAct", "id": "P16104", "url": "https://www.ebi.ac.uk/intact/interactors/id:P16104*" }, { "database": "iPTMnet", "id": "P16104", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16104" }, { "database": "PubMed", "id": "25923214", "url": "https://pubmed.ncbi.nlm.nih.gov/25923214" }, { "database": "PubMed", "id": "22064073", "url": "https://pubmed.ncbi.nlm.nih.gov/22064073" }, { "database": "PubMed", "id": "20118229", "url": "https://pubmed.ncbi.nlm.nih.gov/20118229" }, { "database": "PubMed", "id": "20356835", "url": "https://pubmed.ncbi.nlm.nih.gov/20356835" }, { "database": "PRO", "id": "P16104", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=P16104" }, { "database": "PubMed", "id": "10734083", "url": "https://pubmed.ncbi.nlm.nih.gov/10734083" }, { "database": "PubMed", "id": "10959836", "url": "https://pubmed.ncbi.nlm.nih.gov/10959836" }, { "database": "PubMed", "id": "12660252", "url": "https://pubmed.ncbi.nlm.nih.gov/12660252" }, { "database": "PubMed", "id": "18370922", "url": "https://pubmed.ncbi.nlm.nih.gov/18370922" }, { "database": "PubMed", "id": "12697768", "url": "https://pubmed.ncbi.nlm.nih.gov/12697768" }, { "database": "PubMed", "id": "26124332", "url": "https://pubmed.ncbi.nlm.nih.gov/26124332" }, { "database": "PubMed", "id": "11673449", "url": "https://pubmed.ncbi.nlm.nih.gov/11673449" }, { "database": "PubMed", "id": "12419185", "url": "https://pubmed.ncbi.nlm.nih.gov/12419185" }, { "database": "PubMed", "id": "12607005", "url": "https://pubmed.ncbi.nlm.nih.gov/12607005" }, { "database": "PubMed", "id": "14627815", "url": "https://pubmed.ncbi.nlm.nih.gov/14627815" }, { "database": "PubMed", "id": "15059890", "url": "https://pubmed.ncbi.nlm.nih.gov/15059890" }, { "database": "PubMed", "id": "15489221", "url": "https://pubmed.ncbi.nlm.nih.gov/15489221" }, { "database": "PubMed", "id": "15613478", "url": "https://pubmed.ncbi.nlm.nih.gov/15613478" }, { "database": "PubMed", "id": "17525332", "url": "https://pubmed.ncbi.nlm.nih.gov/17525332" }, { "database": "PubMed", "id": "17709392", "url": "https://pubmed.ncbi.nlm.nih.gov/17709392" }, { "database": "PubMed", "id": "20068231", "url": "https://pubmed.ncbi.nlm.nih.gov/20068231" }, { "database": "PubMed", "id": "21406692", "url": "https://pubmed.ncbi.nlm.nih.gov/21406692" }, { "database": "PubMed", "id": "22154951", "url": "https://pubmed.ncbi.nlm.nih.gov/22154951" }, { "database": "PubMed", "id": "9488723", "url": "https://pubmed.ncbi.nlm.nih.gov/9488723" }, { "database": "PubMed", "id": "10477747", "url": "https://pubmed.ncbi.nlm.nih.gov/10477747" } ], "site_lbl": "Ser140", "uniprot_canonical_ac": "P16104-1" } ], "record_id": "pubmed.18370922", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Wild-type p53-induced phosphatase 1 dephosphorylates histone variant gamma-H2AX and suppresses DNA double strand break repair.", "journal": "The Journal of biological chemistry", "date": "2010-04-23", "authors": "Moon Sung-Hwan, Lin Lin, Zhang Xinna, Nguyen Thuy-Ai, Darlington Yolanda, Waldman Alan S, Lu Xiongbin, Donehower Lawrence A", "reference": { "type": "PubMed", "id": "20118229", "url": "https://pubmed.ncbi.nlm.nih.gov/20118229" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P16104-1", "protein_name": "Histone H2AX", "gene_name": "H2AX", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P16104", "url": "https://www.uniprot.org/uniprotkb/P16104" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 140, "end_pos": 140, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by ATM, ATR and PRKDC", "evidence": [ { "database": "UniProtKB", "id": "P16104", "url": "https://www.uniprot.org/uniprotkb/P16104" }, { "database": "IntAct", "id": "P16104", "url": "https://www.ebi.ac.uk/intact/interactors/id:P16104*" }, { "database": "iPTMnet", "id": "P16104", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16104" }, { "database": "PubMed", "id": "25923214", "url": "https://pubmed.ncbi.nlm.nih.gov/25923214" }, { "database": "PubMed", "id": "22064073", "url": "https://pubmed.ncbi.nlm.nih.gov/22064073" }, { "database": "PubMed", "id": "20118229", "url": "https://pubmed.ncbi.nlm.nih.gov/20118229" }, { "database": "PubMed", "id": "20356835", "url": "https://pubmed.ncbi.nlm.nih.gov/20356835" }, { "database": "PRO", "id": "P16104", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=P16104" }, { "database": "PubMed", "id": "10734083", "url": "https://pubmed.ncbi.nlm.nih.gov/10734083" }, { "database": "PubMed", "id": "10959836", "url": "https://pubmed.ncbi.nlm.nih.gov/10959836" }, { "database": "PubMed", "id": "12660252", "url": "https://pubmed.ncbi.nlm.nih.gov/12660252" }, { "database": "PubMed", "id": "18370922", "url": "https://pubmed.ncbi.nlm.nih.gov/18370922" }, { "database": "PubMed", "id": "12697768", "url": "https://pubmed.ncbi.nlm.nih.gov/12697768" }, { "database": "PubMed", "id": "26124332", "url": "https://pubmed.ncbi.nlm.nih.gov/26124332" }, { "database": "PubMed", "id": "11673449", "url": "https://pubmed.ncbi.nlm.nih.gov/11673449" }, { "database": "PubMed", "id": "12419185", "url": "https://pubmed.ncbi.nlm.nih.gov/12419185" }, { "database": "PubMed", "id": "12607005", "url": "https://pubmed.ncbi.nlm.nih.gov/12607005" }, { "database": "PubMed", "id": "14627815", "url": "https://pubmed.ncbi.nlm.nih.gov/14627815" }, { "database": "PubMed", "id": "15059890", "url": "https://pubmed.ncbi.nlm.nih.gov/15059890" }, { "database": "PubMed", "id": "15489221", "url": "https://pubmed.ncbi.nlm.nih.gov/15489221" }, { "database": "PubMed", "id": "15613478", "url": "https://pubmed.ncbi.nlm.nih.gov/15613478" }, { "database": "PubMed", "id": "17525332", "url": "https://pubmed.ncbi.nlm.nih.gov/17525332" }, { "database": "PubMed", "id": "17709392", "url": "https://pubmed.ncbi.nlm.nih.gov/17709392" }, { "database": "PubMed", "id": "20068231", "url": "https://pubmed.ncbi.nlm.nih.gov/20068231" }, { "database": "PubMed", "id": "21406692", "url": "https://pubmed.ncbi.nlm.nih.gov/21406692" }, { "database": "PubMed", "id": "22154951", "url": "https://pubmed.ncbi.nlm.nih.gov/22154951" }, { "database": "PubMed", "id": "9488723", "url": "https://pubmed.ncbi.nlm.nih.gov/9488723" }, { "database": "PubMed", "id": "10477747", "url": "https://pubmed.ncbi.nlm.nih.gov/10477747" } ], "site_lbl": "Ser140", "uniprot_canonical_ac": "P16104-1" } ], "record_id": "pubmed.20118229", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Phosphorylation of histone H2A.X by DNA-dependent protein kinase is not affected by core histone acetylation, but it alters nucleosome stability and histone H1 binding.", "journal": "The Journal of biological chemistry", "date": "2010", "authors": "Li A, Yu Y, Lee SC, Ishibashi T, Lees-Miller SP, Ausio J", "reference": { "type": "PubMed", "id": "20356835", "url": "https://pubmed.ncbi.nlm.nih.gov/20356835" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P16104-1", "protein_name": "Histone H2AX", "gene_name": "H2AX", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P16104", "url": "https://www.uniprot.org/uniprotkb/P16104" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 137, "end_pos": 137, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P16104", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16104" }, { "database": "PubMed", "id": "9488723", "url": "https://pubmed.ncbi.nlm.nih.gov/9488723" }, { "database": "PubMed", "id": "20356835", "url": "https://pubmed.ncbi.nlm.nih.gov/20356835" } ], "site_lbl": "Thr137", "uniprot_canonical_ac": "P16104-1" }, { "start_pos": 140, "end_pos": 140, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by ATM, ATR and PRKDC", "evidence": [ { "database": "UniProtKB", "id": "P16104", "url": "https://www.uniprot.org/uniprotkb/P16104" }, { "database": "IntAct", "id": "P16104", "url": "https://www.ebi.ac.uk/intact/interactors/id:P16104*" }, { "database": "iPTMnet", "id": "P16104", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16104" }, { "database": "PubMed", "id": "25923214", "url": "https://pubmed.ncbi.nlm.nih.gov/25923214" }, { "database": "PubMed", "id": "22064073", "url": "https://pubmed.ncbi.nlm.nih.gov/22064073" }, { "database": "PubMed", "id": "20118229", "url": "https://pubmed.ncbi.nlm.nih.gov/20118229" }, { "database": "PubMed", "id": "20356835", "url": "https://pubmed.ncbi.nlm.nih.gov/20356835" }, { "database": "PRO", "id": "P16104", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=P16104" }, { "database": "PubMed", "id": "10734083", "url": "https://pubmed.ncbi.nlm.nih.gov/10734083" }, { "database": "PubMed", "id": "10959836", "url": "https://pubmed.ncbi.nlm.nih.gov/10959836" }, { "database": "PubMed", "id": "12660252", "url": "https://pubmed.ncbi.nlm.nih.gov/12660252" }, { "database": "PubMed", "id": "18370922", "url": "https://pubmed.ncbi.nlm.nih.gov/18370922" }, { "database": "PubMed", "id": "12697768", "url": "https://pubmed.ncbi.nlm.nih.gov/12697768" }, { "database": "PubMed", "id": "26124332", "url": "https://pubmed.ncbi.nlm.nih.gov/26124332" }, { "database": "PubMed", "id": "11673449", "url": "https://pubmed.ncbi.nlm.nih.gov/11673449" }, { "database": "PubMed", "id": "12419185", "url": "https://pubmed.ncbi.nlm.nih.gov/12419185" }, { "database": "PubMed", "id": "12607005", "url": "https://pubmed.ncbi.nlm.nih.gov/12607005" }, { "database": "PubMed", "id": "14627815", "url": "https://pubmed.ncbi.nlm.nih.gov/14627815" }, { "database": "PubMed", "id": "15059890", "url": "https://pubmed.ncbi.nlm.nih.gov/15059890" }, { "database": "PubMed", "id": "15489221", "url": "https://pubmed.ncbi.nlm.nih.gov/15489221" }, { "database": "PubMed", "id": "15613478", "url": "https://pubmed.ncbi.nlm.nih.gov/15613478" }, { "database": "PubMed", "id": "17525332", "url": "https://pubmed.ncbi.nlm.nih.gov/17525332" }, { "database": "PubMed", "id": "17709392", "url": "https://pubmed.ncbi.nlm.nih.gov/17709392" }, { "database": "PubMed", "id": "20068231", "url": "https://pubmed.ncbi.nlm.nih.gov/20068231" }, { "database": "PubMed", "id": "21406692", "url": "https://pubmed.ncbi.nlm.nih.gov/21406692" }, { "database": "PubMed", "id": "22154951", "url": "https://pubmed.ncbi.nlm.nih.gov/22154951" }, { "database": "PubMed", "id": "9488723", "url": "https://pubmed.ncbi.nlm.nih.gov/9488723" }, { "database": "PubMed", "id": "10477747", "url": "https://pubmed.ncbi.nlm.nih.gov/10477747" } ], "site_lbl": "Ser140", "uniprot_canonical_ac": "P16104-1" } ], "record_id": "pubmed.20356835", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Critical role of monoubiquitination of histone H2AX protein in histone H2AX phosphorylation and DNA damage response.", "journal": "The Journal of biological chemistry", "date": "2011", "authors": "Wu CY, Kang HY, Yang WL, Wu J, Jeong YS, Wang J, Chan CH, Lee SW, Zhang X, Lamothe B, Campos AD, Darnay BG, Lin HK", "reference": { "type": "PubMed", "id": "21690091", "url": "https://pubmed.ncbi.nlm.nih.gov/21690091" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P16104-1", "protein_name": "Histone H2AX", "gene_name": "H2AX", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P16104", "url": "https://www.uniprot.org/uniprotkb/P16104" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 140, "end_pos": 140, "kinase_uniprot_canonical_ac": "Q13315-1", "kinase_gene_name": "ATM", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P16104", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16104" }, { "database": "PubMed", "id": "11571274", "url": "https://pubmed.ncbi.nlm.nih.gov/11571274" }, { "database": "PubMed", "id": "11893489", "url": "https://pubmed.ncbi.nlm.nih.gov/11893489" }, { "database": "PubMed", "id": "20068231", "url": "https://pubmed.ncbi.nlm.nih.gov/20068231" }, { "database": "PubMed", "id": "9488723", "url": "https://pubmed.ncbi.nlm.nih.gov/9488723" }, { "database": "PubMed", "id": "18158901", "url": "https://pubmed.ncbi.nlm.nih.gov/18158901" }, { "database": "PubMed", "id": "21690091", "url": "https://pubmed.ncbi.nlm.nih.gov/21690091" } ], "site_lbl": "Ser140", "uniprot_canonical_ac": "P16104-1" } ], "record_id": "pubmed.21690091", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Structural basis of \u03b3H2AX recognition by human PTIP BRCT5-BRCT6 domains in the DNA damage response pathway.", "journal": "FEBS letters", "date": "2011-12-15", "authors": "Yan Wei, Shao Zhenhua, Li Fudong, Niu Liwen, Shi Yunyu, Teng Maikun, Li Xu", "reference": { "type": "PubMed", "id": "22064073", "url": "https://pubmed.ncbi.nlm.nih.gov/22064073" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P16104-1", "protein_name": "Histone H2AX", "gene_name": "H2AX", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P16104", "url": "https://www.uniprot.org/uniprotkb/P16104" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 140, "end_pos": 140, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by ATM, ATR and PRKDC", "evidence": [ { "database": "UniProtKB", "id": "P16104", "url": "https://www.uniprot.org/uniprotkb/P16104" }, { "database": "IntAct", "id": "P16104", "url": "https://www.ebi.ac.uk/intact/interactors/id:P16104*" }, { "database": "iPTMnet", "id": "P16104", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16104" }, { "database": "PubMed", "id": "25923214", "url": "https://pubmed.ncbi.nlm.nih.gov/25923214" }, { "database": "PubMed", "id": "22064073", "url": "https://pubmed.ncbi.nlm.nih.gov/22064073" }, { "database": "PubMed", "id": "20118229", "url": "https://pubmed.ncbi.nlm.nih.gov/20118229" }, { "database": "PubMed", "id": "20356835", "url": "https://pubmed.ncbi.nlm.nih.gov/20356835" }, { "database": "PRO", "id": "P16104", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=P16104" }, { "database": "PubMed", "id": "10734083", "url": "https://pubmed.ncbi.nlm.nih.gov/10734083" }, { "database": "PubMed", "id": "10959836", "url": "https://pubmed.ncbi.nlm.nih.gov/10959836" }, { "database": "PubMed", "id": "12660252", "url": "https://pubmed.ncbi.nlm.nih.gov/12660252" }, { "database": "PubMed", "id": "18370922", "url": "https://pubmed.ncbi.nlm.nih.gov/18370922" }, { "database": "PubMed", "id": "12697768", "url": "https://pubmed.ncbi.nlm.nih.gov/12697768" }, { "database": "PubMed", "id": "26124332", "url": "https://pubmed.ncbi.nlm.nih.gov/26124332" }, { "database": "PubMed", "id": "11673449", "url": "https://pubmed.ncbi.nlm.nih.gov/11673449" }, { "database": "PubMed", "id": "12419185", "url": "https://pubmed.ncbi.nlm.nih.gov/12419185" }, { "database": "PubMed", "id": "12607005", "url": "https://pubmed.ncbi.nlm.nih.gov/12607005" }, { "database": "PubMed", "id": "14627815", "url": "https://pubmed.ncbi.nlm.nih.gov/14627815" }, { "database": "PubMed", "id": "15059890", "url": "https://pubmed.ncbi.nlm.nih.gov/15059890" }, { "database": "PubMed", "id": "15489221", "url": "https://pubmed.ncbi.nlm.nih.gov/15489221" }, { "database": "PubMed", "id": "15613478", "url": "https://pubmed.ncbi.nlm.nih.gov/15613478" }, { "database": "PubMed", "id": "17525332", "url": "https://pubmed.ncbi.nlm.nih.gov/17525332" }, { "database": "PubMed", "id": "17709392", "url": "https://pubmed.ncbi.nlm.nih.gov/17709392" }, { "database": "PubMed", "id": "20068231", "url": "https://pubmed.ncbi.nlm.nih.gov/20068231" }, { "database": "PubMed", "id": "21406692", "url": "https://pubmed.ncbi.nlm.nih.gov/21406692" }, { "database": "PubMed", "id": "22154951", "url": "https://pubmed.ncbi.nlm.nih.gov/22154951" }, { "database": "PubMed", "id": "9488723", "url": "https://pubmed.ncbi.nlm.nih.gov/9488723" }, { "database": "PubMed", "id": "10477747", "url": "https://pubmed.ncbi.nlm.nih.gov/10477747" } ], "site_lbl": "Ser140", "uniprot_canonical_ac": "P16104-1" } ], "record_id": "pubmed.22064073", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Specific recognition of phosphorylated tail of H2AX by the tandem BRCT domains of MCPH1 revealed by complex structure.", "journal": "Journal of structural biology", "date": "2012", "authors": "Shao Z, Li F, Sy SM, Yan W, Zhang Z, Gong D, Wen B, Huen MS, Gong Q, Wu J, Shi Y", "reference": { "type": "PubMed", "id": "22154951", "url": "https://pubmed.ncbi.nlm.nih.gov/22154951" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P16104-1", "protein_name": "Histone H2AX", "gene_name": "H2AX", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NEM0-1", "protein_name": "Microcephalin", "gene_name": "MCPH1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P16104", "url": "https://www.uniprot.org/uniprotkb/P16104" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 140, "end_pos": 140, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by ATM, ATR and PRKDC", "evidence": [ { "database": "UniProtKB", "id": "P16104", "url": "https://www.uniprot.org/uniprotkb/P16104" }, { "database": "IntAct", "id": "P16104", "url": "https://www.ebi.ac.uk/intact/interactors/id:P16104*" }, { "database": "iPTMnet", "id": "P16104", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16104" }, { "database": "PubMed", "id": "25923214", "url": "https://pubmed.ncbi.nlm.nih.gov/25923214" }, { "database": "PubMed", "id": "22064073", "url": "https://pubmed.ncbi.nlm.nih.gov/22064073" }, { "database": "PubMed", "id": "20118229", "url": "https://pubmed.ncbi.nlm.nih.gov/20118229" }, { "database": "PubMed", "id": "20356835", "url": "https://pubmed.ncbi.nlm.nih.gov/20356835" }, { "database": "PRO", "id": "P16104", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=P16104" }, { "database": "PubMed", "id": "10734083", "url": "https://pubmed.ncbi.nlm.nih.gov/10734083" }, { "database": "PubMed", "id": "10959836", "url": "https://pubmed.ncbi.nlm.nih.gov/10959836" }, { "database": "PubMed", "id": "12660252", "url": "https://pubmed.ncbi.nlm.nih.gov/12660252" }, { "database": "PubMed", "id": "18370922", "url": "https://pubmed.ncbi.nlm.nih.gov/18370922" }, { "database": "PubMed", "id": "12697768", "url": "https://pubmed.ncbi.nlm.nih.gov/12697768" }, { "database": "PubMed", "id": "26124332", "url": "https://pubmed.ncbi.nlm.nih.gov/26124332" }, { "database": "PubMed", "id": "11673449", "url": "https://pubmed.ncbi.nlm.nih.gov/11673449" }, { "database": "PubMed", "id": "12419185", "url": "https://pubmed.ncbi.nlm.nih.gov/12419185" }, { "database": "PubMed", "id": "12607005", "url": "https://pubmed.ncbi.nlm.nih.gov/12607005" }, { "database": "PubMed", "id": "14627815", "url": "https://pubmed.ncbi.nlm.nih.gov/14627815" }, { "database": "PubMed", "id": "15059890", "url": "https://pubmed.ncbi.nlm.nih.gov/15059890" }, { "database": "PubMed", "id": "15489221", "url": "https://pubmed.ncbi.nlm.nih.gov/15489221" }, { "database": "PubMed", "id": "15613478", "url": "https://pubmed.ncbi.nlm.nih.gov/15613478" }, { "database": "PubMed", "id": "17525332", "url": "https://pubmed.ncbi.nlm.nih.gov/17525332" }, { "database": "PubMed", "id": "17709392", "url": "https://pubmed.ncbi.nlm.nih.gov/17709392" }, { "database": "PubMed", "id": "20068231", "url": "https://pubmed.ncbi.nlm.nih.gov/20068231" }, { "database": "PubMed", "id": "21406692", "url": "https://pubmed.ncbi.nlm.nih.gov/21406692" }, { "database": "PubMed", "id": "22154951", "url": "https://pubmed.ncbi.nlm.nih.gov/22154951" }, { "database": "PubMed", "id": "9488723", "url": "https://pubmed.ncbi.nlm.nih.gov/9488723" }, { "database": "PubMed", "id": "10477747", "url": "https://pubmed.ncbi.nlm.nih.gov/10477747" } ], "site_lbl": "Ser140", "uniprot_canonical_ac": "P16104-1" } ], "record_id": "pubmed.22154951", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Epstein-Barr virus essential antigen EBNA3C attenuates H2AX expression.", "journal": "J. Virol.", "date": "2014", "authors": "Jha Hem C, A J Mahadesh Prasad, Saha Abhik, Banerjee Shuvomoy, Lu Jie, Robertson Erle S", "reference": { "type": "PubMed", "id": "24429368", "url": "https://pubmed.ncbi.nlm.nih.gov/24429368" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P16104-1", "protein_name": "Histone H2AX", "gene_name": "H2AX", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P16104", "url": "https://www.uniprot.org/uniprotkb/P16104" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.24429368", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "H2A.X. a histone isoprotein with a conserved C-terminal sequence, is encoded by a novel mRNA with both DNA replication type and polyA 3' processing signals.", "journal": "Nucleic Acids Res.", "date": "1989", "authors": "Mannironi C, Bonner W M, Hatch C L", "reference": { "type": "PubMed", "id": "2587254", "url": "https://pubmed.ncbi.nlm.nih.gov/2587254" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P16104-1", "protein_name": "Histone H2AX", "gene_name": "H2AX", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P16104", "url": "https://www.uniprot.org/uniprotkb/P16104" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.2587254", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "VRK1 chromatin kinase phosphorylates H2AX and is required for foci formation induced by DNA damage.", "journal": "Epigenetics", "date": "2015", "authors": "Salzano M, Sanz-Garcia M, Monsalve DM, Moura DS, Lazo PA", "reference": { "type": "PubMed", "id": "25923214", "url": "https://pubmed.ncbi.nlm.nih.gov/25923214" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P16104-1", "protein_name": "Histone H2AX", "gene_name": "H2AX", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13315-1", "protein_name": "Serine-protein kinase ATM", "gene_name": "ATM", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P16104", "url": "https://www.uniprot.org/uniprotkb/P16104" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 140, "end_pos": 140, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by ATM, ATR and PRKDC", "evidence": [ { "database": "UniProtKB", "id": "P16104", "url": "https://www.uniprot.org/uniprotkb/P16104" }, { "database": "IntAct", "id": "P16104", "url": "https://www.ebi.ac.uk/intact/interactors/id:P16104*" }, { "database": "iPTMnet", "id": "P16104", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16104" }, { "database": "PubMed", "id": "25923214", "url": "https://pubmed.ncbi.nlm.nih.gov/25923214" }, { "database": "PubMed", "id": "22064073", "url": "https://pubmed.ncbi.nlm.nih.gov/22064073" }, { "database": "PubMed", "id": "20118229", "url": "https://pubmed.ncbi.nlm.nih.gov/20118229" }, { "database": "PubMed", "id": "20356835", "url": "https://pubmed.ncbi.nlm.nih.gov/20356835" }, { "database": "PRO", "id": "P16104", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=P16104" }, { "database": "PubMed", "id": "10734083", "url": "https://pubmed.ncbi.nlm.nih.gov/10734083" }, { "database": "PubMed", "id": "10959836", "url": "https://pubmed.ncbi.nlm.nih.gov/10959836" }, { "database": "PubMed", "id": "12660252", "url": "https://pubmed.ncbi.nlm.nih.gov/12660252" }, { "database": "PubMed", "id": "18370922", "url": "https://pubmed.ncbi.nlm.nih.gov/18370922" }, { "database": "PubMed", "id": "12697768", "url": "https://pubmed.ncbi.nlm.nih.gov/12697768" }, { "database": "PubMed", "id": "26124332", "url": "https://pubmed.ncbi.nlm.nih.gov/26124332" }, { "database": "PubMed", "id": "11673449", "url": "https://pubmed.ncbi.nlm.nih.gov/11673449" }, { "database": "PubMed", "id": "12419185", "url": "https://pubmed.ncbi.nlm.nih.gov/12419185" }, { "database": "PubMed", "id": "12607005", "url": "https://pubmed.ncbi.nlm.nih.gov/12607005" }, { "database": "PubMed", "id": "14627815", "url": "https://pubmed.ncbi.nlm.nih.gov/14627815" }, { "database": "PubMed", "id": "15059890", "url": "https://pubmed.ncbi.nlm.nih.gov/15059890" }, { "database": "PubMed", "id": "15489221", "url": "https://pubmed.ncbi.nlm.nih.gov/15489221" }, { "database": "PubMed", "id": "15613478", "url": "https://pubmed.ncbi.nlm.nih.gov/15613478" }, { "database": "PubMed", "id": "17525332", "url": "https://pubmed.ncbi.nlm.nih.gov/17525332" }, { "database": "PubMed", "id": "17709392", "url": "https://pubmed.ncbi.nlm.nih.gov/17709392" }, { "database": "PubMed", "id": "20068231", "url": "https://pubmed.ncbi.nlm.nih.gov/20068231" }, { "database": "PubMed", "id": "21406692", "url": "https://pubmed.ncbi.nlm.nih.gov/21406692" }, { "database": "PubMed", "id": "22154951", "url": "https://pubmed.ncbi.nlm.nih.gov/22154951" }, { "database": "PubMed", "id": "9488723", "url": "https://pubmed.ncbi.nlm.nih.gov/9488723" }, { "database": "PubMed", "id": "10477747", "url": "https://pubmed.ncbi.nlm.nih.gov/10477747" } ], "site_lbl": "Ser140", "uniprot_canonical_ac": "P16104-1" }, { "start_pos": 1981, "end_pos": 1981, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by autocatalysis", "evidence": [ { "database": "UniProtKB", "id": "Q13315", "url": "https://www.uniprot.org/uniprotkb/Q13315" }, { "database": "IntAct", "id": "Q13315", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q13315*" }, { "database": "iPTMnet", "id": "Q13315", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q13315" }, { "database": "PubMed", "id": "19851285", "url": "https://pubmed.ncbi.nlm.nih.gov/19851285" }, { "database": "PubMed", "id": "16858402", "url": "https://pubmed.ncbi.nlm.nih.gov/16858402" }, { "database": "PRO", "id": "Q13315", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=Q13315" }, { "database": "PubMed", "id": "22099307", "url": "https://pubmed.ncbi.nlm.nih.gov/22099307" }, { "database": "PubMed", "id": "12556884", "url": "https://pubmed.ncbi.nlm.nih.gov/12556884" }, { "database": "PubMed", "id": "14695167", "url": "https://pubmed.ncbi.nlm.nih.gov/14695167" }, { "database": "PubMed", "id": "14871926", "url": "https://pubmed.ncbi.nlm.nih.gov/14871926" }, { "database": "PubMed", "id": "15048089", "url": "https://pubmed.ncbi.nlm.nih.gov/15048089" }, { "database": "PubMed", "id": "15140942", "url": "https://pubmed.ncbi.nlm.nih.gov/15140942" }, { "database": "PubMed", "id": "15177039", "url": "https://pubmed.ncbi.nlm.nih.gov/15177039" }, { "database": "PubMed", "id": "15177184", "url": "https://pubmed.ncbi.nlm.nih.gov/15177184" }, { "database": "PubMed", "id": "15269203", "url": "https://pubmed.ncbi.nlm.nih.gov/15269203" }, { "database": "PubMed", "id": "15313175", "url": "https://pubmed.ncbi.nlm.nih.gov/15313175" }, { "database": "PubMed", "id": "15314656", "url": "https://pubmed.ncbi.nlm.nih.gov/15314656" }, { "database": "PubMed", "id": "15489221", "url": "https://pubmed.ncbi.nlm.nih.gov/15489221" }, { "database": "PubMed", "id": "15510216", "url": "https://pubmed.ncbi.nlm.nih.gov/15510216" }, { "database": "PubMed", "id": "15846060", "url": "https://pubmed.ncbi.nlm.nih.gov/15846060" }, { "database": "PubMed", "id": "16293623", "url": "https://pubmed.ncbi.nlm.nih.gov/16293623" }, { "database": "PubMed", "id": "16319535", "url": "https://pubmed.ncbi.nlm.nih.gov/16319535" }, { "database": "PubMed", "id": "16452482", "url": "https://pubmed.ncbi.nlm.nih.gov/16452482" }, { "database": "PubMed", "id": "16528719", "url": "https://pubmed.ncbi.nlm.nih.gov/16528719" }, { "database": "PubMed", "id": "16533058", "url": "https://pubmed.ncbi.nlm.nih.gov/16533058" }, { "database": "PubMed", "id": "16556909", "url": "https://pubmed.ncbi.nlm.nih.gov/16556909" }, { "database": "PubMed", "id": "16628011", "url": "https://pubmed.ncbi.nlm.nih.gov/16628011" }, { "database": "PubMed", "id": "16636671", "url": "https://pubmed.ncbi.nlm.nih.gov/16636671" }, { "database": "PubMed", "id": "16861926", "url": "https://pubmed.ncbi.nlm.nih.gov/16861926" }, { "database": "PubMed", "id": "16906133", "url": "https://pubmed.ncbi.nlm.nih.gov/16906133" }, { "database": "PubMed", "id": "16940754", "url": "https://pubmed.ncbi.nlm.nih.gov/16940754" }, { "database": "PubMed", "id": "16997395", "url": "https://pubmed.ncbi.nlm.nih.gov/16997395" }, { "database": "PubMed", "id": "17016017", "url": "https://pubmed.ncbi.nlm.nih.gov/17016017" }, { "database": "PubMed", "id": "17124492", "url": "https://pubmed.ncbi.nlm.nih.gov/17124492" }, { "database": "PubMed", "id": "17406032", "url": "https://pubmed.ncbi.nlm.nih.gov/17406032" }, { "database": "PubMed", "id": "17486112", "url": "https://pubmed.ncbi.nlm.nih.gov/17486112" }, { "database": "PubMed", "id": "17638905", "url": "https://pubmed.ncbi.nlm.nih.gov/17638905" }, { "database": "PubMed", "id": "17700524", "url": "https://pubmed.ncbi.nlm.nih.gov/17700524" }, { "database": "PubMed", "id": "18048416", "url": "https://pubmed.ncbi.nlm.nih.gov/18048416" }, { "database": "PubMed", "id": "18059176", "url": "https://pubmed.ncbi.nlm.nih.gov/18059176" }, { "database": "PubMed", "id": "18248856", "url": "https://pubmed.ncbi.nlm.nih.gov/18248856" }, { "database": "PubMed", "id": "18344987", "url": "https://pubmed.ncbi.nlm.nih.gov/18344987" }, { "database": "PubMed", "id": "18431490", "url": "https://pubmed.ncbi.nlm.nih.gov/18431490" }, { "database": "PubMed", "id": "18560558", "url": "https://pubmed.ncbi.nlm.nih.gov/18560558" }, { "database": "PubMed", "id": "18571408", "url": "https://pubmed.ncbi.nlm.nih.gov/18571408" }, { "database": "PubMed", "id": "18593910", "url": "https://pubmed.ncbi.nlm.nih.gov/18593910" }, { "database": "PubMed", "id": "18596698", "url": "https://pubmed.ncbi.nlm.nih.gov/18596698" }, { "database": "PubMed", "id": "18619531", "url": "https://pubmed.ncbi.nlm.nih.gov/18619531" }, { "database": "PubMed", "id": "18663430", "url": "https://pubmed.ncbi.nlm.nih.gov/18663430" }, { "database": "PubMed", "id": "18762365", "url": "https://pubmed.ncbi.nlm.nih.gov/18762365" }, { "database": "PubMed", "id": "18959818", "url": "https://pubmed.ncbi.nlm.nih.gov/18959818" }, { "database": "PubMed", "id": "18985806", "url": "https://pubmed.ncbi.nlm.nih.gov/18985806" }, { "database": "PubMed", "id": "19401701", "url": "https://pubmed.ncbi.nlm.nih.gov/19401701" }, { "database": "PubMed", "id": "19411853", "url": "https://pubmed.ncbi.nlm.nih.gov/19411853" }, { "database": "PubMed", "id": "19451263", "url": "https://pubmed.ncbi.nlm.nih.gov/19451263" }, { "database": "PubMed", "id": "19605351", "url": "https://pubmed.ncbi.nlm.nih.gov/19605351" }, { "database": "PubMed", "id": "19621083", "url": "https://pubmed.ncbi.nlm.nih.gov/19621083" }, { "database": "PubMed", "id": "19625493", "url": "https://pubmed.ncbi.nlm.nih.gov/19625493" }, { "database": "PubMed", "id": "19658174", "url": "https://pubmed.ncbi.nlm.nih.gov/19658174" }, { "database": "PubMed", "id": "19671522", "url": "https://pubmed.ncbi.nlm.nih.gov/19671522" }, { "database": "PubMed", "id": "19744477", "url": "https://pubmed.ncbi.nlm.nih.gov/19744477" }, { "database": "PubMed", "id": "19798429", "url": "https://pubmed.ncbi.nlm.nih.gov/19798429" }, { "database": "PubMed", "id": "20014310", "url": "https://pubmed.ncbi.nlm.nih.gov/20014310" }, { "database": "PubMed", "id": "20126263", "url": "https://pubmed.ncbi.nlm.nih.gov/20126263" }, { "database": "PubMed", "id": "20205745", "url": "https://pubmed.ncbi.nlm.nih.gov/20205745" }, { "database": "PubMed", "id": "20660628", "url": "https://pubmed.ncbi.nlm.nih.gov/20660628" }, { "database": "PubMed", "id": "20678255", "url": "https://pubmed.ncbi.nlm.nih.gov/20678255" }, { "database": "PubMed", "id": "20700484", "url": "https://pubmed.ncbi.nlm.nih.gov/20700484" }, { "database": "PubMed", "id": "20711462", "url": "https://pubmed.ncbi.nlm.nih.gov/20711462" }, { "database": "PubMed", "id": "20959117", "url": "https://pubmed.ncbi.nlm.nih.gov/20959117" }, { "database": "PubMed", "id": "20976220", "url": "https://pubmed.ncbi.nlm.nih.gov/20976220" }, { "database": "PubMed", "id": "20978201", "url": "https://pubmed.ncbi.nlm.nih.gov/20978201" }, { "database": "PubMed", "id": "21078189", "url": "https://pubmed.ncbi.nlm.nih.gov/21078189" }, { "database": "PubMed", "id": "21157431", "url": "https://pubmed.ncbi.nlm.nih.gov/21157431" }, { "database": "PubMed", "id": "21219611", "url": "https://pubmed.ncbi.nlm.nih.gov/21219611" }, { "database": "PubMed", "id": "21292467", "url": "https://pubmed.ncbi.nlm.nih.gov/21292467" }, { "database": "PubMed", "id": "21338495", "url": "https://pubmed.ncbi.nlm.nih.gov/21338495" }, { "database": "PubMed", "id": "21390062", "url": "https://pubmed.ncbi.nlm.nih.gov/21390062" }, { "database": "PubMed", "id": "21573174", "url": "https://pubmed.ncbi.nlm.nih.gov/21573174" }, { "database": "PubMed", "id": "21824286", "url": "https://pubmed.ncbi.nlm.nih.gov/21824286" }, { "database": "PubMed", "id": "21997193", "url": "https://pubmed.ncbi.nlm.nih.gov/21997193" }, { "database": "PubMed", "id": "22323184", "url": "https://pubmed.ncbi.nlm.nih.gov/22323184" }, { "database": "PubMed", "id": "22416035", "url": "https://pubmed.ncbi.nlm.nih.gov/22416035" }, { "database": "PubMed", "id": "22493319", "url": "https://pubmed.ncbi.nlm.nih.gov/22493319" }, { "database": "PubMed", "id": "22498490", "url": "https://pubmed.ncbi.nlm.nih.gov/22498490" }, { "database": "PubMed", "id": "22655027", "url": "https://pubmed.ncbi.nlm.nih.gov/22655027" }, { "database": "PubMed", "id": "22739265", "url": "https://pubmed.ncbi.nlm.nih.gov/22739265" }, { "database": "PubMed", "id": "22761798", "url": "https://pubmed.ncbi.nlm.nih.gov/22761798" }, { "database": "PubMed", "id": "22837425", "url": "https://pubmed.ncbi.nlm.nih.gov/22837425" }, { "database": "PubMed", "id": "22841545", "url": "https://pubmed.ncbi.nlm.nih.gov/22841545" }, { "database": "PubMed", "id": "22952040", "url": "https://pubmed.ncbi.nlm.nih.gov/22952040" }, { "database": "PubMed", "id": "23146902", "url": "https://pubmed.ncbi.nlm.nih.gov/23146902" }, { "database": "PubMed", "id": "23166842", "url": "https://pubmed.ncbi.nlm.nih.gov/23166842" }, { "database": "PubMed", "id": "23185347", "url": "https://pubmed.ncbi.nlm.nih.gov/23185347" }, { "database": "PubMed", "id": "23193277", "url": "https://pubmed.ncbi.nlm.nih.gov/23193277" }, { "database": "PubMed", "id": "23365634", "url": "https://pubmed.ncbi.nlm.nih.gov/23365634" }, { "database": "PubMed", "id": "23383259", "url": "https://pubmed.ncbi.nlm.nih.gov/23383259" }, { "database": "PubMed", "id": "23533526", "url": "https://pubmed.ncbi.nlm.nih.gov/23533526" }, { "database": "PubMed", "id": "23552604", "url": "https://pubmed.ncbi.nlm.nih.gov/23552604" }, { "database": "PubMed", "id": "23620287", "url": "https://pubmed.ncbi.nlm.nih.gov/23620287" }, { "database": "PubMed", "id": "23666059", "url": "https://pubmed.ncbi.nlm.nih.gov/23666059" }, { "database": "PubMed", "id": "23705030", "url": "https://pubmed.ncbi.nlm.nih.gov/23705030" }, { "database": "PubMed", "id": "23900392", "url": "https://pubmed.ncbi.nlm.nih.gov/23900392" }, { "database": "PubMed", "id": "24086335", "url": "https://pubmed.ncbi.nlm.nih.gov/24086335" }, { "database": "PubMed", "id": "24113180", "url": "https://pubmed.ncbi.nlm.nih.gov/24113180" }, { "database": "PubMed", "id": "24268576", "url": "https://pubmed.ncbi.nlm.nih.gov/24268576" }, { "database": "PubMed", "id": "24280901", "url": "https://pubmed.ncbi.nlm.nih.gov/24280901" }, { "database": "PubMed", "id": "24505404", "url": "https://pubmed.ncbi.nlm.nih.gov/24505404" }, { "database": "PubMed", "id": "24763056", "url": "https://pubmed.ncbi.nlm.nih.gov/24763056" }, { "database": "PubMed", "id": "24812435", "url": "https://pubmed.ncbi.nlm.nih.gov/24812435" }, { "database": "PubMed", "id": "24933654", "url": "https://pubmed.ncbi.nlm.nih.gov/24933654" }, { "database": "PubMed", "id": "24988892", "url": "https://pubmed.ncbi.nlm.nih.gov/24988892" }, { "database": "PubMed", "id": "25003995", "url": "https://pubmed.ncbi.nlm.nih.gov/25003995" }, { "database": "PubMed", "id": "25077176", "url": "https://pubmed.ncbi.nlm.nih.gov/25077176" }, { "database": "PubMed", "id": "25088203", "url": "https://pubmed.ncbi.nlm.nih.gov/25088203" }, { "database": "PubMed", "id": "25111195", "url": "https://pubmed.ncbi.nlm.nih.gov/25111195" }, { "database": "PubMed", "id": "25240135", "url": "https://pubmed.ncbi.nlm.nih.gov/25240135" }, { "database": "PubMed", "id": "25527123", "url": "https://pubmed.ncbi.nlm.nih.gov/25527123" }, { "database": "PubMed", "id": "25611382", "url": "https://pubmed.ncbi.nlm.nih.gov/25611382" }, { "database": "PubMed", "id": "25821946", "url": "https://pubmed.ncbi.nlm.nih.gov/25821946" }, { "database": "PubMed", "id": "25826455", "url": "https://pubmed.ncbi.nlm.nih.gov/25826455" }, { "database": "PubMed", "id": "25865756", "url": "https://pubmed.ncbi.nlm.nih.gov/25865756" }, { "database": "PubMed", "id": "25904696", "url": "https://pubmed.ncbi.nlm.nih.gov/25904696" }, { "database": "PubMed", "id": "25923214", "url": "https://pubmed.ncbi.nlm.nih.gov/25923214" }, { "database": "PubMed", "id": "25977998", "url": "https://pubmed.ncbi.nlm.nih.gov/25977998" }, { "database": "PubMed", "id": "26158765", "url": "https://pubmed.ncbi.nlm.nih.gov/26158765" }, { "database": "PubMed", "id": "26240375", "url": "https://pubmed.ncbi.nlm.nih.gov/26240375" }, { "database": "PubMed", "id": "26275218", "url": "https://pubmed.ncbi.nlm.nih.gov/26275218" }, { "database": "PubMed", "id": "26416514", "url": "https://pubmed.ncbi.nlm.nih.gov/26416514" }, { "database": "PubMed", "id": "26427042", "url": "https://pubmed.ncbi.nlm.nih.gov/26427042" }, { "database": "PubMed", "id": "26431963", "url": "https://pubmed.ncbi.nlm.nih.gov/26431963" }, { "database": "PubMed", "id": "26438152", "url": "https://pubmed.ncbi.nlm.nih.gov/26438152" }, { "database": "PubMed", "id": "26517194", "url": "https://pubmed.ncbi.nlm.nih.gov/26517194" }, { "database": "PubMed", "id": "26517239", "url": "https://pubmed.ncbi.nlm.nih.gov/26517239" }, { "database": "PubMed", "id": "26556501", "url": "https://pubmed.ncbi.nlm.nih.gov/26556501" }, { "database": "PubMed", "id": "26677768", "url": "https://pubmed.ncbi.nlm.nih.gov/26677768" }, { "database": "PubMed", "id": "26683224", "url": "https://pubmed.ncbi.nlm.nih.gov/26683224" }, { "database": "PubMed", "id": "26751069", "url": "https://pubmed.ncbi.nlm.nih.gov/26751069" }, { "database": "PubMed", "id": "26824362", "url": "https://pubmed.ncbi.nlm.nih.gov/26824362" }, { "database": "PubMed", "id": "26860083", "url": "https://pubmed.ncbi.nlm.nih.gov/26860083" }, { "database": "PubMed", "id": "26875667", "url": "https://pubmed.ncbi.nlm.nih.gov/26875667" }, { "database": "PubMed", "id": "26919204", "url": "https://pubmed.ncbi.nlm.nih.gov/26919204" }, { "database": "PubMed", "id": "27029031", "url": "https://pubmed.ncbi.nlm.nih.gov/27029031" }, { "database": "PubMed", "id": "27089984", "url": "https://pubmed.ncbi.nlm.nih.gov/27089984" }, { "database": "PubMed", "id": "27097159", "url": "https://pubmed.ncbi.nlm.nih.gov/27097159" }, { "database": "PubMed", "id": "27258787", "url": "https://pubmed.ncbi.nlm.nih.gov/27258787" }, { "database": "PubMed", "id": "27259260", "url": "https://pubmed.ncbi.nlm.nih.gov/27259260" }, { "database": "PubMed", "id": "27273218", "url": "https://pubmed.ncbi.nlm.nih.gov/27273218" }, { "database": "PubMed", "id": "27391441", "url": "https://pubmed.ncbi.nlm.nih.gov/27391441" }, { "database": "PubMed", "id": "27462418", "url": "https://pubmed.ncbi.nlm.nih.gov/27462418" }, { "database": "PubMed", "id": "27468685", "url": "https://pubmed.ncbi.nlm.nih.gov/27468685" }, { "database": "PubMed", "id": "27524627", "url": "https://pubmed.ncbi.nlm.nih.gov/27524627" }, { "database": "PubMed", "id": "27602502", "url": "https://pubmed.ncbi.nlm.nih.gov/27602502" }, { "database": "PubMed", "id": "27603133", "url": "https://pubmed.ncbi.nlm.nih.gov/27603133" }, { "database": "PubMed", "id": "27613518", "url": "https://pubmed.ncbi.nlm.nih.gov/27613518" }, { "database": "PubMed", "id": "27705915", "url": "https://pubmed.ncbi.nlm.nih.gov/27705915" }, { "database": "PubMed", "id": "27907109", "url": "https://pubmed.ncbi.nlm.nih.gov/27907109" }, { "database": "PubMed", "id": "27959319", "url": "https://pubmed.ncbi.nlm.nih.gov/27959319" }, { "database": "PubMed", "id": "28182994", "url": "https://pubmed.ncbi.nlm.nih.gov/28182994" }, { "database": "PubMed", "id": "28202068", "url": "https://pubmed.ncbi.nlm.nih.gov/28202068" }, { "database": "PubMed", "id": "28250390", "url": "https://pubmed.ncbi.nlm.nih.gov/28250390" }, { "database": "PubMed", "id": "28259977", "url": "https://pubmed.ncbi.nlm.nih.gov/28259977" }, { "database": "PubMed", "id": "28387728", "url": "https://pubmed.ncbi.nlm.nih.gov/28387728" }, { "database": "PubMed", "id": "28412751", "url": "https://pubmed.ncbi.nlm.nih.gov/28412751" }, { "database": "PubMed", "id": "28477111", "url": "https://pubmed.ncbi.nlm.nih.gov/28477111" }, { "database": "PubMed", "id": "28477132", "url": "https://pubmed.ncbi.nlm.nih.gov/28477132" }, { "database": "PubMed", "id": "28648892", "url": "https://pubmed.ncbi.nlm.nih.gov/28648892" }, { "database": "PubMed", "id": "28881600", "url": "https://pubmed.ncbi.nlm.nih.gov/28881600" }, { "database": "PubMed", "id": "28973009", "url": "https://pubmed.ncbi.nlm.nih.gov/28973009" }, { "database": "PubMed", "id": "29048667", "url": "https://pubmed.ncbi.nlm.nih.gov/29048667" }, { "database": "PubMed", "id": "29088817", "url": "https://pubmed.ncbi.nlm.nih.gov/29088817" }, { "database": "PubMed", "id": "29147215", "url": "https://pubmed.ncbi.nlm.nih.gov/29147215" }, { "database": "PubMed", "id": "29294106", "url": "https://pubmed.ncbi.nlm.nih.gov/29294106" }, { "database": "PubMed", "id": "29399146", "url": "https://pubmed.ncbi.nlm.nih.gov/29399146" }, { "database": "PubMed", "id": "29540829", "url": "https://pubmed.ncbi.nlm.nih.gov/29540829" }, { "database": "PubMed", "id": "29615613", "url": "https://pubmed.ncbi.nlm.nih.gov/29615613" }, { "database": "PubMed", "id": "30088201", "url": "https://pubmed.ncbi.nlm.nih.gov/30088201" }, { "database": "PubMed", "id": "30237520", "url": "https://pubmed.ncbi.nlm.nih.gov/30237520" }, { "database": "PubMed", "id": "30245854", "url": "https://pubmed.ncbi.nlm.nih.gov/30245854" }, { "database": "PubMed", "id": "30258062", "url": "https://pubmed.ncbi.nlm.nih.gov/30258062" }, { "database": "PubMed", "id": "30297868", "url": "https://pubmed.ncbi.nlm.nih.gov/30297868" }, { "database": "PubMed", "id": "30473536", "url": "https://pubmed.ncbi.nlm.nih.gov/30473536" }, { "database": "PubMed", "id": "30565836", "url": "https://pubmed.ncbi.nlm.nih.gov/30565836" }, { "database": "PubMed", "id": "30577494", "url": "https://pubmed.ncbi.nlm.nih.gov/30577494" }, { "database": "PubMed", "id": "30679601", "url": "https://pubmed.ncbi.nlm.nih.gov/30679601" }, { "database": "PubMed", "id": "30783677", "url": "https://pubmed.ncbi.nlm.nih.gov/30783677" }, { "database": "PubMed", "id": "30886146", "url": "https://pubmed.ncbi.nlm.nih.gov/30886146" }, { "database": "PubMed", "id": "30943920", "url": "https://pubmed.ncbi.nlm.nih.gov/30943920" }, { "database": "PubMed", "id": "30967632", "url": "https://pubmed.ncbi.nlm.nih.gov/30967632" }, { "database": "PubMed", "id": "31114877", "url": "https://pubmed.ncbi.nlm.nih.gov/31114877" }, { "database": "PubMed", "id": "31164689", "url": "https://pubmed.ncbi.nlm.nih.gov/31164689" }, { "database": "PubMed", "id": "31307507", "url": "https://pubmed.ncbi.nlm.nih.gov/31307507" }, { "database": "PubMed", "id": "31372798", "url": "https://pubmed.ncbi.nlm.nih.gov/31372798" }, { "database": "PubMed", "id": "31481733", "url": "https://pubmed.ncbi.nlm.nih.gov/31481733" }, { "database": "PubMed", "id": "31759252", "url": "https://pubmed.ncbi.nlm.nih.gov/31759252" }, { "database": "PubMed", "id": "31805725", "url": "https://pubmed.ncbi.nlm.nih.gov/31805725" }, { "database": "PubMed", "id": "31827702", "url": "https://pubmed.ncbi.nlm.nih.gov/31827702" }, { "database": "PubMed", "id": "31857852", "url": "https://pubmed.ncbi.nlm.nih.gov/31857852" }, { "database": "PubMed", "id": "32015321", "url": "https://pubmed.ncbi.nlm.nih.gov/32015321" }, { "database": "PubMed", "id": "32059363", "url": "https://pubmed.ncbi.nlm.nih.gov/32059363" }, { "database": "PubMed", "id": "32203529", "url": "https://pubmed.ncbi.nlm.nih.gov/32203529" }, { "database": "PubMed", "id": "32226530", "url": "https://pubmed.ncbi.nlm.nih.gov/32226530" }, { "database": "PubMed", "id": "32377397", "url": "https://pubmed.ncbi.nlm.nih.gov/32377397" }, { "database": "PubMed", "id": "32444694", "url": "https://pubmed.ncbi.nlm.nih.gov/32444694" }, { "database": "PubMed", "id": "32479542", "url": "https://pubmed.ncbi.nlm.nih.gov/32479542" }, { "database": "PubMed", "id": "32665601", "url": "https://pubmed.ncbi.nlm.nih.gov/32665601" }, { "database": "PubMed", "id": "32752095", "url": "https://pubmed.ncbi.nlm.nih.gov/32752095" }, { "database": "PubMed", "id": "32879366", "url": "https://pubmed.ncbi.nlm.nih.gov/32879366" }, { "database": "PubMed", "id": "33024871", "url": "https://pubmed.ncbi.nlm.nih.gov/33024871" }, { "database": "PubMed", "id": "33039867", "url": "https://pubmed.ncbi.nlm.nih.gov/33039867" }, { "database": "PubMed", "id": "33096336", "url": "https://pubmed.ncbi.nlm.nih.gov/33096336" }, { "database": "PubMed", "id": "33245190", "url": "https://pubmed.ncbi.nlm.nih.gov/33245190" }, { "database": "PubMed", "id": "33437944", "url": "https://pubmed.ncbi.nlm.nih.gov/33437944" }, { "database": "PubMed", "id": "33628174", "url": "https://pubmed.ncbi.nlm.nih.gov/33628174" }, { "database": "PubMed", "id": "33802884", "url": "https://pubmed.ncbi.nlm.nih.gov/33802884" }, { "database": "PubMed", "id": "16141325", "url": "https://pubmed.ncbi.nlm.nih.gov/16141325" }, { "database": "PubMed", "id": "17525332", "url": "https://pubmed.ncbi.nlm.nih.gov/17525332" }, { "database": "PubMed", "id": "21144835", "url": "https://pubmed.ncbi.nlm.nih.gov/21144835" }, { "database": "PubMed", "id": "30944854", "url": "https://pubmed.ncbi.nlm.nih.gov/30944854" } ], "site_lbl": "Ser1981", "uniprot_canonical_ac": "Q13315-1" } ], "record_id": "pubmed.25923214", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Curcumin Triggers DNA Damage and Inhibits Expression of DNA Repair Proteins in Human Lung Cancer Cells.", "journal": "Anticancer research", "date": "2015-07", "authors": "Ting Chien-Yi, Wang Hsin-Ell, Yu Chien-Chih, Liu Hsin-Chung, Liu Yu-Chang, Chiang I-Tsang", "reference": { "type": "PubMed", "id": "26124332", "url": "https://pubmed.ncbi.nlm.nih.gov/26124332" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P16104-1", "protein_name": "Histone H2AX", "gene_name": "H2AX", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P16104", "url": "https://www.uniprot.org/uniprotkb/P16104" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 140, "end_pos": 140, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by ATM, ATR and PRKDC", "evidence": [ { "database": "UniProtKB", "id": "P16104", "url": "https://www.uniprot.org/uniprotkb/P16104" }, { "database": "IntAct", "id": "P16104", "url": "https://www.ebi.ac.uk/intact/interactors/id:P16104*" }, { "database": "iPTMnet", "id": "P16104", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16104" }, { "database": "PubMed", "id": "25923214", "url": "https://pubmed.ncbi.nlm.nih.gov/25923214" }, { "database": "PubMed", "id": "22064073", "url": "https://pubmed.ncbi.nlm.nih.gov/22064073" }, { "database": "PubMed", "id": "20118229", "url": "https://pubmed.ncbi.nlm.nih.gov/20118229" }, { "database": "PubMed", "id": "20356835", "url": "https://pubmed.ncbi.nlm.nih.gov/20356835" }, { "database": "PRO", "id": "P16104", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=P16104" }, { "database": "PubMed", "id": "10734083", "url": "https://pubmed.ncbi.nlm.nih.gov/10734083" }, { "database": "PubMed", "id": "10959836", "url": "https://pubmed.ncbi.nlm.nih.gov/10959836" }, { "database": "PubMed", "id": "12660252", "url": "https://pubmed.ncbi.nlm.nih.gov/12660252" }, { "database": "PubMed", "id": "18370922", "url": "https://pubmed.ncbi.nlm.nih.gov/18370922" }, { "database": "PubMed", "id": "12697768", "url": "https://pubmed.ncbi.nlm.nih.gov/12697768" }, { "database": "PubMed", "id": "26124332", "url": "https://pubmed.ncbi.nlm.nih.gov/26124332" }, { "database": "PubMed", "id": "11673449", "url": "https://pubmed.ncbi.nlm.nih.gov/11673449" }, { "database": "PubMed", "id": "12419185", "url": "https://pubmed.ncbi.nlm.nih.gov/12419185" }, { "database": "PubMed", "id": "12607005", "url": "https://pubmed.ncbi.nlm.nih.gov/12607005" }, { "database": "PubMed", "id": "14627815", "url": "https://pubmed.ncbi.nlm.nih.gov/14627815" }, { "database": "PubMed", "id": "15059890", "url": "https://pubmed.ncbi.nlm.nih.gov/15059890" }, { "database": "PubMed", "id": "15489221", "url": "https://pubmed.ncbi.nlm.nih.gov/15489221" }, { "database": "PubMed", "id": "15613478", "url": "https://pubmed.ncbi.nlm.nih.gov/15613478" }, { "database": "PubMed", "id": "17525332", "url": "https://pubmed.ncbi.nlm.nih.gov/17525332" }, { "database": "PubMed", "id": "17709392", "url": "https://pubmed.ncbi.nlm.nih.gov/17709392" }, { "database": "PubMed", "id": "20068231", "url": "https://pubmed.ncbi.nlm.nih.gov/20068231" }, { "database": "PubMed", "id": "21406692", "url": "https://pubmed.ncbi.nlm.nih.gov/21406692" }, { "database": "PubMed", "id": "22154951", "url": "https://pubmed.ncbi.nlm.nih.gov/22154951" }, { "database": "PubMed", "id": "9488723", "url": "https://pubmed.ncbi.nlm.nih.gov/9488723" }, { "database": "PubMed", "id": "10477747", "url": "https://pubmed.ncbi.nlm.nih.gov/10477747" } ], "site_lbl": "Ser140", "uniprot_canonical_ac": "P16104-1" } ], "record_id": "pubmed.26124332", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "gamma-H2AX: A potential biomarker in breast cancer.", "journal": "Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine", "date": "2019", "authors": "Varvara PV, Karaolanis G, Valavanis C, Stanc G, Tzaida O, Trihia H, Patapis P, Dimitroulis D, Perrea D", "reference": { "type": "PubMed", "id": "31552812", "url": "https://pubmed.ncbi.nlm.nih.gov/31552812" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P16104-1", "protein_name": "Histone H2AX", "gene_name": "H2AX", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P16104", "url": "https://www.uniprot.org/uniprotkb/P16104" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "biomarkers": [ { "best_biomarker_role": [ "prognostic" ], "biomarker_canonical_id": "AN6495", "assessed_biomarker_entity": [ "Histone H2AX" ], "biomarker_id": "AN6495-1", "biomarker": [ "increased H2AX level" ], "condition": { "id": "DOID:1612", "recommended_name": { "id": "DOID:1612", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland." }, "name_list": [ "breast cancer", "breast tumor", "malignant neoplasm of breast", "malignant tumor of the breast", "mammary cancer", "mammary tumor", "primary breast cancer", "hereditary breast carcinoma", "breast cancer susceptibility, autosomal dominant, somatic mutation", "breast cancer, early-onset, susceptibility to, autosomal dominant, somatic mutation", "breast cancer, invasive ductal, autosomal dominant, somatic mutation", "breast cancer, lobular, somatic", "breast cancer, male, susceptibility to, autosomal dominant, somatic mutation", "breast cancer, protection against, autosomal dominant, somatic mutation", "breast cancer, somatic", "breast cancer, susceptibility to, autosomal dominant, somatic mutation", "familial breast cancer", "familial breast carcinoma", "familial cancer of breast", "familial cancer of the breast", "hereditary breast cancer", "Breast cancer" ], "id_list": [ "DOID:1612", "MONDO:0016419", "MIM:114480" ] } } ], "record_id": "pubmed.31552812", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Machine learning extracts oncogenic-specific \u03b3-H2AX foci formation pattern upon genotoxic stress.", "journal": "Genes to cells : devoted to molecular & cellular mechanisms", "date": "2022-12-24", "authors": "Furuya Kanji, Ikura Masae, Ikura Tsuyoshi", "reference": { "type": "PubMed", "id": "36565298", "url": "https://pubmed.ncbi.nlm.nih.gov/36565298" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P16104-1", "protein_name": "Histone H2AX", "gene_name": "H2AX", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P16104", "url": "https://www.uniprot.org/uniprotkb/P16104" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.36565298", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Hypoxia-responsive lncRNA G077640 promotes ESCC tumorigenesis via the H2AX-HIF1\u03b1-glycolysis axis.", "journal": "Carcinogenesis", "date": "2023-08-10", "authors": "Huang Xiaomei, Liu Chunxia, Li Hao, Dai Tianyang, Luo Gang, Zhang Chunxiang, Li Tao, L\u00fc Muhan", "reference": { "type": "PubMed", "id": "37248865", "url": "https://pubmed.ncbi.nlm.nih.gov/37248865" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P16104-1", "protein_name": "Histone H2AX", "gene_name": "H2AX", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P16104", "url": "https://www.uniprot.org/uniprotkb/P16104" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.37248865", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "H2AX promotes replication fork degradation and chemosensitivity in BRCA-deficient tumours.", "journal": "Nature communications", "date": "2024-05-24", "authors": "Dibitetto Diego, Liptay Martin, Vivalda Francesca, Dogan H\u00fclya, Gogola Ewa, Gonz\u00e1lez Fern\u00e1ndez Mart\u00edn, Duarte Alexandra, Schmid Jonas A, Decollogny Morgane, Francica Paola, Przetocka Sara, Durant Stephen T, Forment Josep V, Klebic Ismar, Siffert Myriam, de Bruijn Roebi, Kousholt Arne N, Marti Nicole A, Dettwiler Martina, S\u00f8rensen Claus S, Tille Jean-Christophe, Undurraga Manuela, Labidi-Galy Intidhar, Lopes Massimo, Sartori Alessandro A, Jonkers Jos, Rottenberg Sven", "reference": { "type": "PubMed", "id": "38789420", "url": "https://pubmed.ncbi.nlm.nih.gov/38789420" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P16104-1", "protein_name": "Histone H2AX", "gene_name": "H2AX", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P16104", "url": "https://www.uniprot.org/uniprotkb/P16104" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.38789420", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Overexpression of H2AFX gene in neuroblastoma is associated with worse prognosis.", "journal": "Pediatric blood & cancer", "date": "2024-09", "authors": "Ognibene Marzia, Parodi Stefano, Amoroso Loredana, Zara Federico, Pezzolo Annalisa", "reference": { "type": "PubMed", "id": "38938078", "url": "https://pubmed.ncbi.nlm.nih.gov/38938078" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P16104-1", "protein_name": "Histone H2AX", "gene_name": "H2AX", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P16104", "url": "https://www.uniprot.org/uniprotkb/P16104" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.38938078", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Novel allele of the insulin receptor substrate-1 bearing two non-conservative amino acid substitutions in a patient with noninsulin-dependent diabetes mellitus. Mutations in brief no. 130. Online.", "journal": "Human mutation", "date": "1998", "authors": "Mammarella S, Creati B, Esposito DL, Arcuri P, Della Loggia F, Capani F, Mariani-Costantini R, Caramia FG, Battista P, Cama A", "reference": { "type": "PubMed", "id": "10206679", "url": "https://pubmed.ncbi.nlm.nih.gov/10206679" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.10206679", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Crystal structure of the pleckstrin homology-phosphotyrosine binding (PH-PTB) targeting region of insulin receptor substrate 1.", "journal": "Proc. Natl. Acad. Sci. U.S.A.", "date": "1999", "authors": "Dhe-Paganon S, Ottinger E A, Nolte R T, Eck M J, Shoelson S E", "reference": { "type": "PubMed", "id": "10411883", "url": "https://pubmed.ncbi.nlm.nih.gov/10411883" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.10411883", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The c-Jun NH(2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser(307).", "journal": "The Journal of biological chemistry", "date": "2000", "authors": "Aguirre V, Uchida T, Yenush L, Davis R, White MF", "reference": { "type": "PubMed", "id": "10722755", "url": "https://pubmed.ncbi.nlm.nih.gov/10722755" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 312, "end_pos": 312, "kinase_uniprot_canonical_ac": "O14920-1", "kinase_gene_name": "IKBKB", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "10722755", "url": "https://pubmed.ncbi.nlm.nih.gov/10722755" }, { "database": "PubMed", "id": "11606564", "url": "https://pubmed.ncbi.nlm.nih.gov/11606564" }, { "database": "PubMed", "id": "12351658", "url": "https://pubmed.ncbi.nlm.nih.gov/12351658" } ], "site_lbl": "Ser312", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 312, "end_pos": 312, "kinase_uniprot_canonical_ac": "P45983-1", "kinase_gene_name": "MAPK8", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "10722755", "url": "https://pubmed.ncbi.nlm.nih.gov/10722755" }, { "database": "PubMed", "id": "11606564", "url": "https://pubmed.ncbi.nlm.nih.gov/11606564" }, { "database": "PubMed", "id": "12351658", "url": "https://pubmed.ncbi.nlm.nih.gov/12351658" }, { "database": "PubMed", "id": "18728222", "url": "https://pubmed.ncbi.nlm.nih.gov/18728222" } ], "site_lbl": "Ser312", "uniprot_canonical_ac": "P35568-1" } ], "record_id": "pubmed.10722755", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The Gly-->Arg(972) amino acid polymorphism in insulin receptor substrate-1 affects glucose metabolism in skeletal muscle cells.", "journal": "J. Clin. Endocrinol. Metab.", "date": "2000", "authors": "Hribal M L, Federici M, Porzio O, Lauro D, Borboni P, Accili D, Lauro R, Sesti G", "reference": { "type": "PubMed", "id": "10843189", "url": "https://pubmed.ncbi.nlm.nih.gov/10843189" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.10843189", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Frap-dependent serine phosphorylation of IRS-1 inhibits IRS-1 tyrosine phosphorylation.", "journal": "Biochemical and biophysical research communications", "date": "2001", "authors": "Hartman ME, Villela-Bach M, Chen J, Freund GG", "reference": { "type": "PubMed", "id": "11162588", "url": "https://pubmed.ncbi.nlm.nih.gov/11162588" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 612, "end_pos": 612, "kinase_uniprot_canonical_ac": "P23458-1", "kinase_gene_name": "JAK1", "residue": "Tyr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "11162588", "url": "https://pubmed.ncbi.nlm.nih.gov/11162588" } ], "site_lbl": "Tyr612", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 632, "end_pos": 632, "kinase_uniprot_canonical_ac": "P23458-1", "kinase_gene_name": "JAK1", "residue": "Tyr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "11162588", "url": "https://pubmed.ncbi.nlm.nih.gov/11162588" } ], "site_lbl": "Tyr632", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 662, "end_pos": 662, "kinase_uniprot_canonical_ac": "P23458-1", "kinase_gene_name": "JAK1", "residue": "Tyr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "11162588", "url": "https://pubmed.ncbi.nlm.nih.gov/11162588" } ], "site_lbl": "Tyr662", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 732, "end_pos": 732, "kinase_uniprot_canonical_ac": "P23458-1", "kinase_gene_name": "JAK1", "residue": "Tyr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "11162588", "url": "https://pubmed.ncbi.nlm.nih.gov/11162588" } ], "site_lbl": "Tyr732", "uniprot_canonical_ac": "P35568-1" } ], "record_id": "pubmed.11162588", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 4 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Src homology 3 domain-dependent interaction of Nck-2 with insulin receptor substrate-1.", "journal": "The Biochemical journal", "date": "2001-03-01", "authors": "Tu Y, Liang L, Frank S J, Wu C", "reference": { "type": "PubMed", "id": "11171109", "url": "https://pubmed.ncbi.nlm.nih.gov/11171109" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43639-1", "protein_name": "Cytoplasmic protein NCK2", "gene_name": "NCK2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 234, "end_pos": 234, "sequence_org": "W", "sequence_mut": "K", "comment": "Abolishes interaction with DOCK1 and IRS1.", "evidence": [ { "database": "UniProtKB", "id": "O43639", "url": "https://www.uniprot.org/uniprotkb/O43639" }, { "database": "PubMed", "id": "11240126", "url": "https://pubmed.ncbi.nlm.nih.gov/11240126" }, { "database": "PubMed", "id": "11171109", "url": "https://pubmed.ncbi.nlm.nih.gov/11171109" } ], "uniprot_canonical_ac": "O43639-1" } ], "record_id": "pubmed.11171109", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Split luciferase as an optical probe for detecting protein-protein interactions in mammalian cells based on protein splicing.", "journal": "Analytical chemistry", "date": "2001-06-01", "authors": "Ozawa T, Kaihara A, Sato M, Tachihara K, Umezawa Y", "reference": { "type": "PubMed", "id": "11403293", "url": "https://pubmed.ncbi.nlm.nih.gov/11403293" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 941, "end_pos": 941, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by INSR", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "12220227", "url": "https://pubmed.ncbi.nlm.nih.gov/12220227" }, { "database": "IntAct", "id": "P35568", "url": "https://www.ebi.ac.uk/intact/interactors/id:P35568*" }, { "database": "PubMed", "id": "14632132", "url": "https://pubmed.ncbi.nlm.nih.gov/14632132" }, { "database": "PubMed", "id": "11403293", "url": "https://pubmed.ncbi.nlm.nih.gov/11403293" }, { "database": "PRO", "id": "P35568", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=P35568" }, { "database": "PubMed", "id": "20685959", "url": "https://pubmed.ncbi.nlm.nih.gov/20685959" }, { "database": "PubMed", "id": "22617042", "url": "https://pubmed.ncbi.nlm.nih.gov/22617042" }, { "database": "PubMed", "id": "25299696", "url": "https://pubmed.ncbi.nlm.nih.gov/25299696" }, { "database": "PubMed", "id": "26378251", "url": "https://pubmed.ncbi.nlm.nih.gov/26378251" } ], "site_lbl": "Tyr941", "uniprot_canonical_ac": "P35568-1" } ], "record_id": "pubmed.11403293", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Serine phosphorylation of insulin receptor substrate 1 by inhibitor kappa B kinase complex.", "journal": "The Journal of biological chemistry", "date": "2002", "authors": "Gao Z, Hwang D, Bataille F, Lefevre M, York D, Quon MJ, Ye J", "reference": { "type": "PubMed", "id": "12351658", "url": "https://pubmed.ncbi.nlm.nih.gov/12351658" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 268, "end_pos": 268, "kinase_uniprot_canonical_ac": "O14920-1", "kinase_gene_name": "IKBKB", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "12351658", "url": "https://pubmed.ncbi.nlm.nih.gov/12351658" } ], "site_lbl": "Ser268", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 270, "end_pos": 270, "kinase_uniprot_canonical_ac": "O14920-1", "kinase_gene_name": "IKBKB", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "12351658", "url": "https://pubmed.ncbi.nlm.nih.gov/12351658" }, { "database": "PubMed", "id": "18077418", "url": "https://pubmed.ncbi.nlm.nih.gov/18077418" }, { "database": "PubMed", "id": "19651622", "url": "https://pubmed.ncbi.nlm.nih.gov/19651622" } ], "site_lbl": "Ser270", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 272, "end_pos": 272, "kinase_uniprot_canonical_ac": "O14920-1", "kinase_gene_name": "IKBKB", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "12351658", "url": "https://pubmed.ncbi.nlm.nih.gov/12351658" } ], "site_lbl": "Ser272", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 274, "end_pos": 274, "kinase_uniprot_canonical_ac": "O14920-1", "kinase_gene_name": "IKBKB", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "12351658", "url": "https://pubmed.ncbi.nlm.nih.gov/12351658" } ], "site_lbl": "Ser274", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 307, "end_pos": 307, "kinase_uniprot_canonical_ac": "O14920-1", "kinase_gene_name": "IKBKB", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "12351658", "url": "https://pubmed.ncbi.nlm.nih.gov/12351658" } ], "site_lbl": "Ser307", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 312, "end_pos": 312, "kinase_uniprot_canonical_ac": "O14920-1", "kinase_gene_name": "IKBKB", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "10722755", "url": "https://pubmed.ncbi.nlm.nih.gov/10722755" }, { "database": "PubMed", "id": "11606564", "url": "https://pubmed.ncbi.nlm.nih.gov/11606564" }, { "database": "PubMed", "id": "12351658", "url": "https://pubmed.ncbi.nlm.nih.gov/12351658" } ], "site_lbl": "Ser312", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 312, "end_pos": 312, "kinase_uniprot_canonical_ac": "P45983-1", "kinase_gene_name": "MAPK8", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "10722755", "url": "https://pubmed.ncbi.nlm.nih.gov/10722755" }, { "database": "PubMed", "id": "11606564", "url": "https://pubmed.ncbi.nlm.nih.gov/11606564" }, { "database": "PubMed", "id": "12351658", "url": "https://pubmed.ncbi.nlm.nih.gov/12351658" }, { "database": "PubMed", "id": "18728222", "url": "https://pubmed.ncbi.nlm.nih.gov/18728222" } ], "site_lbl": "Ser312", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 312, "end_pos": 312, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by IKKB, MAPK8 and RPS6KB1", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "12351658", "url": "https://pubmed.ncbi.nlm.nih.gov/12351658" }, { "database": "PubMed", "id": "12510059", "url": "https://pubmed.ncbi.nlm.nih.gov/12510059" }, { "database": "PubMed", "id": "14769130", "url": "https://pubmed.ncbi.nlm.nih.gov/14769130" }, { "database": "PubMed", "id": "15044323", "url": "https://pubmed.ncbi.nlm.nih.gov/15044323" }, { "database": "PubMed", "id": "15613682", "url": "https://pubmed.ncbi.nlm.nih.gov/15613682" }, { "database": "PubMed", "id": "15713122", "url": "https://pubmed.ncbi.nlm.nih.gov/15713122" }, { "database": "PubMed", "id": "15952059", "url": "https://pubmed.ncbi.nlm.nih.gov/15952059" }, { "database": "PubMed", "id": "16123357", "url": "https://pubmed.ncbi.nlm.nih.gov/16123357" }, { "database": "PubMed", "id": "16284649", "url": "https://pubmed.ncbi.nlm.nih.gov/16284649" }, { "database": "PubMed", "id": "16505239", "url": "https://pubmed.ncbi.nlm.nih.gov/16505239" }, { "database": "PubMed", "id": "16505244", "url": "https://pubmed.ncbi.nlm.nih.gov/16505244" }, { "database": "PubMed", "id": "16516141", "url": "https://pubmed.ncbi.nlm.nih.gov/16516141" }, { "database": "PubMed", "id": "16960890", "url": "https://pubmed.ncbi.nlm.nih.gov/16960890" }, { "database": "PubMed", "id": "17204522", "url": "https://pubmed.ncbi.nlm.nih.gov/17204522" }, { "database": "PubMed", "id": "17242212", "url": "https://pubmed.ncbi.nlm.nih.gov/17242212" }, { "database": "PubMed", "id": "17360977", "url": "https://pubmed.ncbi.nlm.nih.gov/17360977" }, { "database": "PubMed", "id": "17647275", "url": "https://pubmed.ncbi.nlm.nih.gov/17647275" }, { "database": "PubMed", "id": "18160431", "url": "https://pubmed.ncbi.nlm.nih.gov/18160431" }, { "database": "PubMed", "id": "19501568", "url": "https://pubmed.ncbi.nlm.nih.gov/19501568" }, { "database": "PubMed", "id": "19567513", "url": "https://pubmed.ncbi.nlm.nih.gov/19567513" }, { "database": "PubMed", "id": "19593406", "url": "https://pubmed.ncbi.nlm.nih.gov/19593406" }, { "database": "PubMed", "id": "20393162", "url": "https://pubmed.ncbi.nlm.nih.gov/20393162" }, { "database": "PubMed", "id": "20685959", "url": "https://pubmed.ncbi.nlm.nih.gov/20685959" }, { "database": "PubMed", "id": "20863384", "url": "https://pubmed.ncbi.nlm.nih.gov/20863384" }, { "database": "PubMed", "id": "21040800", "url": "https://pubmed.ncbi.nlm.nih.gov/21040800" }, { "database": "PubMed", "id": "21252690", "url": "https://pubmed.ncbi.nlm.nih.gov/21252690" }, { "database": "PubMed", "id": "21589939", "url": "https://pubmed.ncbi.nlm.nih.gov/21589939" }, { "database": "PubMed", "id": "21852229", "url": "https://pubmed.ncbi.nlm.nih.gov/21852229" }, { "database": "PubMed", "id": "21937042", "url": "https://pubmed.ncbi.nlm.nih.gov/21937042" }, { "database": "PubMed", "id": "22348058", "url": "https://pubmed.ncbi.nlm.nih.gov/22348058" }, { "database": "PubMed", "id": "22457223", "url": "https://pubmed.ncbi.nlm.nih.gov/22457223" }, { "database": "PubMed", "id": "22862962", "url": "https://pubmed.ncbi.nlm.nih.gov/22862962" }, { "database": "PubMed", "id": "25580119", "url": "https://pubmed.ncbi.nlm.nih.gov/25580119" }, { "database": "PubMed", "id": "27207509", "url": "https://pubmed.ncbi.nlm.nih.gov/27207509" }, { "database": "PubMed", "id": "27340831", "url": "https://pubmed.ncbi.nlm.nih.gov/27340831" }, { "database": "PubMed", "id": "32536688", "url": "https://pubmed.ncbi.nlm.nih.gov/32536688" }, { "database": "PubMed", "id": "33173197", "url": "https://pubmed.ncbi.nlm.nih.gov/33173197" }, { "database": "PubMed", "id": "35833836", "url": "https://pubmed.ncbi.nlm.nih.gov/35833836" }, { "database": "PubMed", "id": "18498745", "url": "https://pubmed.ncbi.nlm.nih.gov/18498745" } ], "site_lbl": "Ser312", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 341, "end_pos": 341, "kinase_uniprot_canonical_ac": "O14920-1", "kinase_gene_name": "IKBKB", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "12351658", "url": "https://pubmed.ncbi.nlm.nih.gov/12351658" } ], "site_lbl": "Ser341", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 345, "end_pos": 345, "kinase_uniprot_canonical_ac": "O14920-1", "kinase_gene_name": "IKBKB", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "12351658", "url": "https://pubmed.ncbi.nlm.nih.gov/12351658" } ], "site_lbl": "Ser345", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 527, "end_pos": 527, "kinase_uniprot_canonical_ac": "O14920-1", "kinase_gene_name": "IKBKB", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "12351658", "url": "https://pubmed.ncbi.nlm.nih.gov/12351658" }, { "database": "PubMed", "id": "19651622", "url": "https://pubmed.ncbi.nlm.nih.gov/19651622" } ], "site_lbl": "Ser527", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 531, "end_pos": 531, "kinase_uniprot_canonical_ac": "O14920-1", "kinase_gene_name": "IKBKB", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "12351658", "url": "https://pubmed.ncbi.nlm.nih.gov/12351658" }, { "database": "PubMed", "id": "19651622", "url": "https://pubmed.ncbi.nlm.nih.gov/19651622" } ], "site_lbl": "Ser531", "uniprot_canonical_ac": "P35568-1" } ], "record_id": "pubmed.12351658", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 12 }, { "field": "total_sites", "count": 10 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Salicylic acid reverses phorbol 12-myristate-13-acetate (PMA)- and tumor necrosis factor alpha (TNFalpha)-induced insulin receptor substrate 1 (IRS1) serine 307 phosphorylation and insulin resistance in human embryonic kidney 293 (HEK293) cells.", "journal": "The Journal of biological chemistry", "date": "2003", "authors": "Jiang G, Dallas-Yang Q, Liu F, Moller DE, Zhang BB", "reference": { "type": "PubMed", "id": "12409308", "url": "https://pubmed.ncbi.nlm.nih.gov/12409308" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 307, "end_pos": 307, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by RPS6KB1", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "11160134", "url": "https://pubmed.ncbi.nlm.nih.gov/11160134" }, { "database": "PubMed", "id": "11606564", "url": "https://pubmed.ncbi.nlm.nih.gov/11606564" }, { "database": "PubMed", "id": "12409308", "url": "https://pubmed.ncbi.nlm.nih.gov/12409308" }, { "database": "PubMed", "id": "12714600", "url": "https://pubmed.ncbi.nlm.nih.gov/12714600" }, { "database": "PubMed", "id": "12730242", "url": "https://pubmed.ncbi.nlm.nih.gov/12730242" }, { "database": "PubMed", "id": "14556646", "url": "https://pubmed.ncbi.nlm.nih.gov/14556646" }, { "database": "PubMed", "id": "14583092", "url": "https://pubmed.ncbi.nlm.nih.gov/14583092" }, { "database": "PubMed", "id": "14641015", "url": "https://pubmed.ncbi.nlm.nih.gov/14641015" }, { "database": "PubMed", "id": "14697666", "url": "https://pubmed.ncbi.nlm.nih.gov/14697666" }, { "database": "PubMed", "id": "15020250", "url": "https://pubmed.ncbi.nlm.nih.gov/15020250" }, { "database": "PubMed", "id": "15153564", "url": "https://pubmed.ncbi.nlm.nih.gov/15153564" }, { "database": "PubMed", "id": "15582605", "url": "https://pubmed.ncbi.nlm.nih.gov/15582605" }, { "database": "PubMed", "id": "15802620", "url": "https://pubmed.ncbi.nlm.nih.gov/15802620" }, { "database": "PubMed", "id": "16046301", "url": "https://pubmed.ncbi.nlm.nih.gov/16046301" }, { "database": "PubMed", "id": "16055440", "url": "https://pubmed.ncbi.nlm.nih.gov/16055440" }, { "database": "PubMed", "id": "16099428", "url": "https://pubmed.ncbi.nlm.nih.gov/16099428" }, { "database": "PubMed", "id": "16210322", "url": "https://pubmed.ncbi.nlm.nih.gov/16210322" }, { "database": "PubMed", "id": "16269459", "url": "https://pubmed.ncbi.nlm.nih.gov/16269459" }, { "database": "PubMed", "id": "16516141", "url": "https://pubmed.ncbi.nlm.nih.gov/16516141" }, { "database": "PubMed", "id": "16754954", "url": "https://pubmed.ncbi.nlm.nih.gov/16754954" }, { "database": "PubMed", "id": "16839860", "url": "https://pubmed.ncbi.nlm.nih.gov/16839860" }, { "database": "PubMed", "id": "17077083", "url": "https://pubmed.ncbi.nlm.nih.gov/17077083" }, { "database": "PubMed", "id": "17095576", "url": "https://pubmed.ncbi.nlm.nih.gov/17095576" }, { "database": "PubMed", "id": "17276034", "url": "https://pubmed.ncbi.nlm.nih.gov/17276034" }, { "database": "PubMed", "id": "17481767", "url": "https://pubmed.ncbi.nlm.nih.gov/17481767" }, { "database": "PubMed", "id": "17575262", "url": "https://pubmed.ncbi.nlm.nih.gov/17575262" }, { "database": "PubMed", "id": "18187553", "url": "https://pubmed.ncbi.nlm.nih.gov/18187553" }, { "database": "PubMed", "id": "18372392", "url": "https://pubmed.ncbi.nlm.nih.gov/18372392" }, { "database": "PubMed", "id": "18380932", "url": "https://pubmed.ncbi.nlm.nih.gov/18380932" }, { "database": "PubMed", "id": "18496818", "url": "https://pubmed.ncbi.nlm.nih.gov/18496818" }, { "database": "PubMed", "id": "18952604", "url": "https://pubmed.ncbi.nlm.nih.gov/18952604" }, { "database": "PubMed", "id": "19095745", "url": "https://pubmed.ncbi.nlm.nih.gov/19095745" }, { "database": "PubMed", "id": "19524129", "url": "https://pubmed.ncbi.nlm.nih.gov/19524129" }, { "database": "PubMed", "id": "19897715", "url": "https://pubmed.ncbi.nlm.nih.gov/19897715" }, { "database": "PubMed", "id": "20351777", "url": "https://pubmed.ncbi.nlm.nih.gov/20351777" }, { "database": "PubMed", "id": "20382011", "url": "https://pubmed.ncbi.nlm.nih.gov/20382011" }, { "database": "PubMed", "id": "20384568", "url": "https://pubmed.ncbi.nlm.nih.gov/20384568" }, { "database": "PubMed", "id": "20541543", "url": "https://pubmed.ncbi.nlm.nih.gov/20541543" }, { "database": "PubMed", "id": "20587749", "url": "https://pubmed.ncbi.nlm.nih.gov/20587749" }, { "database": "PubMed", "id": "20594161", "url": "https://pubmed.ncbi.nlm.nih.gov/20594161" }, { "database": "PubMed", "id": "20594757", "url": "https://pubmed.ncbi.nlm.nih.gov/20594757" }, { "database": "PubMed", "id": "20702573", "url": "https://pubmed.ncbi.nlm.nih.gov/20702573" }, { "database": "PubMed", "id": "21119656", "url": "https://pubmed.ncbi.nlm.nih.gov/21119656" }, { "database": "PubMed", "id": "21478152", "url": "https://pubmed.ncbi.nlm.nih.gov/21478152" }, { "database": "PubMed", "id": "21505982", "url": "https://pubmed.ncbi.nlm.nih.gov/21505982" }, { "database": "PubMed", "id": "21786209", "url": "https://pubmed.ncbi.nlm.nih.gov/21786209" }, { "database": "PubMed", "id": "21852229", "url": "https://pubmed.ncbi.nlm.nih.gov/21852229" }, { "database": "PubMed", "id": "21900690", "url": "https://pubmed.ncbi.nlm.nih.gov/21900690" }, { "database": "PubMed", "id": "22046423", "url": "https://pubmed.ncbi.nlm.nih.gov/22046423" }, { "database": "PubMed", "id": "22227580", "url": "https://pubmed.ncbi.nlm.nih.gov/22227580" }, { "database": "PubMed", "id": "22266116", "url": "https://pubmed.ncbi.nlm.nih.gov/22266116" }, { "database": "PubMed", "id": "22328823", "url": "https://pubmed.ncbi.nlm.nih.gov/22328823" }, { "database": "PubMed", "id": "22348058", "url": "https://pubmed.ncbi.nlm.nih.gov/22348058" }, { "database": "PubMed", "id": "22491740", "url": "https://pubmed.ncbi.nlm.nih.gov/22491740" }, { "database": "PubMed", "id": "22728372", "url": "https://pubmed.ncbi.nlm.nih.gov/22728372" }, { "database": "PubMed", "id": "22766331", "url": "https://pubmed.ncbi.nlm.nih.gov/22766331" }, { "database": "PubMed", "id": "23095254", "url": "https://pubmed.ncbi.nlm.nih.gov/23095254" }, { "database": "PubMed", "id": "23174405", "url": "https://pubmed.ncbi.nlm.nih.gov/23174405" }, { "database": "PubMed", "id": "23182460", "url": "https://pubmed.ncbi.nlm.nih.gov/23182460" }, { "database": "PubMed", "id": "23481042", "url": "https://pubmed.ncbi.nlm.nih.gov/23481042" }, { "database": "PubMed", "id": "23566306", "url": "https://pubmed.ncbi.nlm.nih.gov/23566306" }, { "database": "PubMed", "id": "23592917", "url": "https://pubmed.ncbi.nlm.nih.gov/23592917" }, { "database": "PubMed", "id": "23891856", "url": "https://pubmed.ncbi.nlm.nih.gov/23891856" }, { "database": "PubMed", "id": "23958494", "url": "https://pubmed.ncbi.nlm.nih.gov/23958494" }, { "database": "PubMed", "id": "24068326", "url": "https://pubmed.ncbi.nlm.nih.gov/24068326" }, { "database": "PubMed", "id": "24846082", "url": "https://pubmed.ncbi.nlm.nih.gov/24846082" }, { "database": "PubMed", "id": "25120613", "url": "https://pubmed.ncbi.nlm.nih.gov/25120613" }, { "database": "PubMed", "id": "25355439", "url": "https://pubmed.ncbi.nlm.nih.gov/25355439" }, { "database": "PubMed", "id": "25645159", "url": "https://pubmed.ncbi.nlm.nih.gov/25645159" }, { "database": "PubMed", "id": "25799226", "url": "https://pubmed.ncbi.nlm.nih.gov/25799226" }, { "database": "PubMed", "id": "26604643", "url": "https://pubmed.ncbi.nlm.nih.gov/26604643" }, { "database": "PubMed", "id": "26698173", "url": "https://pubmed.ncbi.nlm.nih.gov/26698173" }, { "database": "PubMed", "id": "26704265", "url": "https://pubmed.ncbi.nlm.nih.gov/26704265" }, { "database": "PubMed", "id": "26899161", "url": "https://pubmed.ncbi.nlm.nih.gov/26899161" }, { "database": "PubMed", "id": "26983645", "url": "https://pubmed.ncbi.nlm.nih.gov/26983645" }, { "database": "PubMed", "id": "27222060", "url": "https://pubmed.ncbi.nlm.nih.gov/27222060" }, { "database": "PubMed", "id": "27506476", "url": "https://pubmed.ncbi.nlm.nih.gov/27506476" }, { "database": "PubMed", "id": "27544192", "url": "https://pubmed.ncbi.nlm.nih.gov/27544192" }, { "database": "PubMed", "id": "27686967", "url": "https://pubmed.ncbi.nlm.nih.gov/27686967" }, { "database": "PubMed", "id": "27936435", "url": "https://pubmed.ncbi.nlm.nih.gov/27936435" }, { "database": "PubMed", "id": "28161417", "url": "https://pubmed.ncbi.nlm.nih.gov/28161417" }, { "database": "PubMed", "id": "28656239", "url": "https://pubmed.ncbi.nlm.nih.gov/28656239" }, { "database": "PubMed", "id": "28731188", "url": "https://pubmed.ncbi.nlm.nih.gov/28731188" }, { "database": "PubMed", "id": "28790390", "url": "https://pubmed.ncbi.nlm.nih.gov/28790390" }, { "database": "PubMed", "id": "28934129", "url": "https://pubmed.ncbi.nlm.nih.gov/28934129" }, { "database": "PubMed", "id": "29177868", "url": "https://pubmed.ncbi.nlm.nih.gov/29177868" }, { "database": "PubMed", "id": "29311680", "url": "https://pubmed.ncbi.nlm.nih.gov/29311680" }, { "database": "PubMed", "id": "29393871", "url": "https://pubmed.ncbi.nlm.nih.gov/29393871" }, { "database": "PubMed", "id": "29432553", "url": "https://pubmed.ncbi.nlm.nih.gov/29432553" }, { "database": "PubMed", "id": "29698741", "url": "https://pubmed.ncbi.nlm.nih.gov/29698741" }, { "database": "PubMed", "id": "29738527", "url": "https://pubmed.ncbi.nlm.nih.gov/29738527" }, { "database": "PubMed", "id": "30240640", "url": "https://pubmed.ncbi.nlm.nih.gov/30240640" }, { "database": "PubMed", "id": "30374127", "url": "https://pubmed.ncbi.nlm.nih.gov/30374127" }, { "database": "PubMed", "id": "30572687", "url": "https://pubmed.ncbi.nlm.nih.gov/30572687" }, { "database": "PubMed", "id": "31137828", "url": "https://pubmed.ncbi.nlm.nih.gov/31137828" }, { "database": "PubMed", "id": "31311314", "url": "https://pubmed.ncbi.nlm.nih.gov/31311314" }, { "database": "PubMed", "id": "31396538", "url": "https://pubmed.ncbi.nlm.nih.gov/31396538" }, { "database": "PubMed", "id": "32875583", "url": "https://pubmed.ncbi.nlm.nih.gov/32875583" }, { "database": "PubMed", "id": "33723215", "url": "https://pubmed.ncbi.nlm.nih.gov/33723215" }, { "database": "PubMed", "id": "35656886", "url": "https://pubmed.ncbi.nlm.nih.gov/35656886" }, { "database": "PubMed", "id": "18498745", "url": "https://pubmed.ncbi.nlm.nih.gov/18498745" } ], "site_lbl": "Ser307", "uniprot_canonical_ac": "P35568-1" } ], "record_id": "pubmed.12409308", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Adipose-specific expression, phosphorylation of Ser794 in insulin receptor substrate-1, and activation in diabetic animals of salt-inducible kinase-2.", "journal": "The Journal of biological chemistry", "date": "2003", "authors": "Horike N, Takemori H, Katoh Y, Doi J, Min L, Asano T, Sun XJ, Yamamoto H, Kasayama S, Muraoka M, Nonaka Y, Okamoto M", "reference": { "type": "PubMed", "id": "12624099", "url": "https://pubmed.ncbi.nlm.nih.gov/12624099" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8CFH6-1", "protein_name": "Serine/threonine-protein kinase SIK2", "gene_name": "Sik2", "tax_name": "Mouse" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 794, "end_pos": 794, "sequence_org": "S", "sequence_mut": "A", "comment": "Loss of phosphorylation by SIK2.", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "PubMed", "id": "12624099", "url": "https://pubmed.ncbi.nlm.nih.gov/12624099" } ], "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 49, "end_pos": 49, "sequence_org": "K", "sequence_mut": "M", "comment": "Loss of kinase activity.", "evidence": [ { "database": "UniProtKB", "id": "Q8CFH6", "url": "https://www.uniprot.org/uniprotkb/Q8CFH6" }, { "database": "PubMed", "id": "12624099", "url": "https://pubmed.ncbi.nlm.nih.gov/12624099" }, { "database": "PubMed", "id": "16817901", "url": "https://pubmed.ncbi.nlm.nih.gov/16817901" } ], "uniprot_canonical_ac": "Q8CFH6-1" } ], "phosphorylation": [ { "start_pos": 794, "end_pos": 794, "kinase_uniprot_canonical_ac": "Q9H0K1-1", "kinase_gene_name": "SIK2", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "12624099", "url": "https://pubmed.ncbi.nlm.nih.gov/12624099" } ], "site_lbl": "Ser794", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 794, "end_pos": 794, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by AMPK and SIK2", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "12006586", "url": "https://pubmed.ncbi.nlm.nih.gov/12006586" }, { "database": "PubMed", "id": "12624099", "url": "https://pubmed.ncbi.nlm.nih.gov/12624099" }, { "database": "PubMed", "id": "17459875", "url": "https://pubmed.ncbi.nlm.nih.gov/17459875" }, { "database": "PubMed", "id": "20363874", "url": "https://pubmed.ncbi.nlm.nih.gov/20363874" }, { "database": "PubMed", "id": "20863384", "url": "https://pubmed.ncbi.nlm.nih.gov/20863384" }, { "database": "PubMed", "id": "31446747", "url": "https://pubmed.ncbi.nlm.nih.gov/31446747" } ], "site_lbl": "Ser794", "uniprot_canonical_ac": "P35568-1" } ], "record_id": "pubmed.12624099", "abstract": "", "glycosylation": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "A novel T608R missense mutation in insulin receptor substrate-1 identified in a subject with type 2 diabetes impairs metabolic insulin signaling.", "journal": "The Journal of clinical endocrinology and metabolism", "date": "2003", "authors": "Esposito DL, Li Y, Vanni C, Mammarella S, Veschi S, Della Loggia F, Mariani-Costantini R, Battista P, Quon MJ, Cama A", "reference": { "type": "PubMed", "id": "12679424", "url": "https://pubmed.ncbi.nlm.nih.gov/12679424" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.12679424", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Hyperosmotic stress inhibits insulin receptor substrate-1 function by distinct mechanisms in 3T3-L1 adipocytes.", "journal": "The Journal of biological chemistry", "date": "2003", "authors": "Gual P, Gonzalez T, Gremeaux T, Barres R, Le Marchand-Brustel Y, Tanti JF", "reference": { "type": "PubMed", "id": "12730242", "url": "https://pubmed.ncbi.nlm.nih.gov/12730242" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 307, "end_pos": 307, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by RPS6KB1", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "11160134", "url": "https://pubmed.ncbi.nlm.nih.gov/11160134" }, { "database": "PubMed", "id": "11606564", "url": "https://pubmed.ncbi.nlm.nih.gov/11606564" }, { "database": "PubMed", "id": "12409308", "url": "https://pubmed.ncbi.nlm.nih.gov/12409308" }, { "database": "PubMed", "id": "12714600", "url": "https://pubmed.ncbi.nlm.nih.gov/12714600" }, { "database": "PubMed", "id": "12730242", "url": "https://pubmed.ncbi.nlm.nih.gov/12730242" }, { "database": "PubMed", "id": "14556646", "url": "https://pubmed.ncbi.nlm.nih.gov/14556646" }, { "database": "PubMed", "id": "14583092", "url": "https://pubmed.ncbi.nlm.nih.gov/14583092" }, { "database": "PubMed", "id": "14641015", "url": "https://pubmed.ncbi.nlm.nih.gov/14641015" }, { "database": "PubMed", "id": "14697666", "url": "https://pubmed.ncbi.nlm.nih.gov/14697666" }, { "database": "PubMed", "id": "15020250", "url": "https://pubmed.ncbi.nlm.nih.gov/15020250" }, { "database": "PubMed", "id": "15153564", "url": "https://pubmed.ncbi.nlm.nih.gov/15153564" }, { "database": "PubMed", "id": "15582605", "url": "https://pubmed.ncbi.nlm.nih.gov/15582605" }, { "database": "PubMed", "id": "15802620", "url": "https://pubmed.ncbi.nlm.nih.gov/15802620" }, { "database": "PubMed", "id": "16046301", "url": "https://pubmed.ncbi.nlm.nih.gov/16046301" }, { "database": "PubMed", "id": "16055440", "url": "https://pubmed.ncbi.nlm.nih.gov/16055440" }, { "database": "PubMed", "id": "16099428", "url": "https://pubmed.ncbi.nlm.nih.gov/16099428" }, { "database": "PubMed", "id": "16210322", "url": "https://pubmed.ncbi.nlm.nih.gov/16210322" }, { "database": "PubMed", "id": "16269459", "url": "https://pubmed.ncbi.nlm.nih.gov/16269459" }, { "database": "PubMed", "id": "16516141", "url": "https://pubmed.ncbi.nlm.nih.gov/16516141" }, { "database": "PubMed", "id": "16754954", "url": "https://pubmed.ncbi.nlm.nih.gov/16754954" }, { "database": "PubMed", "id": "16839860", "url": "https://pubmed.ncbi.nlm.nih.gov/16839860" }, { "database": "PubMed", "id": "17077083", "url": "https://pubmed.ncbi.nlm.nih.gov/17077083" }, { "database": "PubMed", "id": "17095576", "url": "https://pubmed.ncbi.nlm.nih.gov/17095576" }, { "database": "PubMed", "id": "17276034", "url": "https://pubmed.ncbi.nlm.nih.gov/17276034" }, { "database": "PubMed", "id": "17481767", "url": "https://pubmed.ncbi.nlm.nih.gov/17481767" }, { "database": "PubMed", "id": "17575262", "url": "https://pubmed.ncbi.nlm.nih.gov/17575262" }, { "database": "PubMed", "id": "18187553", "url": "https://pubmed.ncbi.nlm.nih.gov/18187553" }, { "database": "PubMed", "id": "18372392", "url": "https://pubmed.ncbi.nlm.nih.gov/18372392" }, { "database": "PubMed", "id": "18380932", "url": "https://pubmed.ncbi.nlm.nih.gov/18380932" }, { "database": "PubMed", "id": "18496818", "url": "https://pubmed.ncbi.nlm.nih.gov/18496818" }, { "database": "PubMed", "id": "18952604", "url": "https://pubmed.ncbi.nlm.nih.gov/18952604" }, { "database": "PubMed", "id": "19095745", "url": "https://pubmed.ncbi.nlm.nih.gov/19095745" }, { "database": "PubMed", "id": "19524129", "url": "https://pubmed.ncbi.nlm.nih.gov/19524129" }, { "database": "PubMed", "id": "19897715", "url": "https://pubmed.ncbi.nlm.nih.gov/19897715" }, { "database": "PubMed", "id": "20351777", "url": "https://pubmed.ncbi.nlm.nih.gov/20351777" }, { "database": "PubMed", "id": "20382011", "url": "https://pubmed.ncbi.nlm.nih.gov/20382011" }, { "database": "PubMed", "id": "20384568", "url": "https://pubmed.ncbi.nlm.nih.gov/20384568" }, { "database": "PubMed", "id": "20541543", "url": "https://pubmed.ncbi.nlm.nih.gov/20541543" }, { "database": "PubMed", "id": "20587749", "url": "https://pubmed.ncbi.nlm.nih.gov/20587749" }, { "database": "PubMed", "id": "20594161", "url": "https://pubmed.ncbi.nlm.nih.gov/20594161" }, { "database": "PubMed", "id": "20594757", "url": "https://pubmed.ncbi.nlm.nih.gov/20594757" }, { "database": "PubMed", "id": "20702573", "url": "https://pubmed.ncbi.nlm.nih.gov/20702573" }, { "database": "PubMed", "id": "21119656", "url": "https://pubmed.ncbi.nlm.nih.gov/21119656" }, { "database": "PubMed", "id": "21478152", "url": "https://pubmed.ncbi.nlm.nih.gov/21478152" }, { "database": "PubMed", "id": "21505982", "url": "https://pubmed.ncbi.nlm.nih.gov/21505982" }, { "database": "PubMed", "id": "21786209", "url": "https://pubmed.ncbi.nlm.nih.gov/21786209" }, { "database": "PubMed", "id": "21852229", "url": "https://pubmed.ncbi.nlm.nih.gov/21852229" }, { "database": "PubMed", "id": "21900690", "url": "https://pubmed.ncbi.nlm.nih.gov/21900690" }, { "database": "PubMed", "id": "22046423", "url": "https://pubmed.ncbi.nlm.nih.gov/22046423" }, { "database": "PubMed", "id": "22227580", "url": "https://pubmed.ncbi.nlm.nih.gov/22227580" }, { "database": "PubMed", "id": "22266116", "url": "https://pubmed.ncbi.nlm.nih.gov/22266116" }, { "database": "PubMed", "id": "22328823", "url": "https://pubmed.ncbi.nlm.nih.gov/22328823" }, { "database": "PubMed", "id": "22348058", "url": "https://pubmed.ncbi.nlm.nih.gov/22348058" }, { "database": "PubMed", "id": "22491740", "url": "https://pubmed.ncbi.nlm.nih.gov/22491740" }, { "database": "PubMed", "id": "22728372", "url": "https://pubmed.ncbi.nlm.nih.gov/22728372" }, { "database": "PubMed", "id": "22766331", "url": "https://pubmed.ncbi.nlm.nih.gov/22766331" }, { "database": "PubMed", "id": "23095254", "url": "https://pubmed.ncbi.nlm.nih.gov/23095254" }, { "database": "PubMed", "id": "23174405", "url": "https://pubmed.ncbi.nlm.nih.gov/23174405" }, { "database": "PubMed", "id": "23182460", "url": "https://pubmed.ncbi.nlm.nih.gov/23182460" }, { "database": "PubMed", "id": "23481042", "url": "https://pubmed.ncbi.nlm.nih.gov/23481042" }, { "database": "PubMed", "id": "23566306", "url": "https://pubmed.ncbi.nlm.nih.gov/23566306" }, { "database": "PubMed", "id": "23592917", "url": "https://pubmed.ncbi.nlm.nih.gov/23592917" }, { "database": "PubMed", "id": "23891856", "url": "https://pubmed.ncbi.nlm.nih.gov/23891856" }, { "database": "PubMed", "id": "23958494", "url": "https://pubmed.ncbi.nlm.nih.gov/23958494" }, { "database": "PubMed", "id": "24068326", "url": "https://pubmed.ncbi.nlm.nih.gov/24068326" }, { "database": "PubMed", "id": "24846082", "url": "https://pubmed.ncbi.nlm.nih.gov/24846082" }, { "database": "PubMed", "id": "25120613", "url": "https://pubmed.ncbi.nlm.nih.gov/25120613" }, { "database": "PubMed", "id": "25355439", "url": "https://pubmed.ncbi.nlm.nih.gov/25355439" }, { "database": "PubMed", "id": "25645159", "url": "https://pubmed.ncbi.nlm.nih.gov/25645159" }, { "database": "PubMed", "id": "25799226", "url": "https://pubmed.ncbi.nlm.nih.gov/25799226" }, { "database": "PubMed", "id": "26604643", "url": "https://pubmed.ncbi.nlm.nih.gov/26604643" }, { "database": "PubMed", "id": "26698173", "url": "https://pubmed.ncbi.nlm.nih.gov/26698173" }, { "database": "PubMed", "id": "26704265", "url": "https://pubmed.ncbi.nlm.nih.gov/26704265" }, { "database": "PubMed", "id": "26899161", "url": "https://pubmed.ncbi.nlm.nih.gov/26899161" }, { "database": "PubMed", "id": "26983645", "url": "https://pubmed.ncbi.nlm.nih.gov/26983645" }, { "database": "PubMed", "id": "27222060", "url": "https://pubmed.ncbi.nlm.nih.gov/27222060" }, { "database": "PubMed", "id": "27506476", "url": "https://pubmed.ncbi.nlm.nih.gov/27506476" }, { "database": "PubMed", "id": "27544192", "url": "https://pubmed.ncbi.nlm.nih.gov/27544192" }, { "database": "PubMed", "id": "27686967", "url": "https://pubmed.ncbi.nlm.nih.gov/27686967" }, { "database": "PubMed", "id": "27936435", "url": "https://pubmed.ncbi.nlm.nih.gov/27936435" }, { "database": "PubMed", "id": "28161417", "url": "https://pubmed.ncbi.nlm.nih.gov/28161417" }, { "database": "PubMed", "id": "28656239", "url": "https://pubmed.ncbi.nlm.nih.gov/28656239" }, { "database": "PubMed", "id": "28731188", "url": "https://pubmed.ncbi.nlm.nih.gov/28731188" }, { "database": "PubMed", "id": "28790390", "url": "https://pubmed.ncbi.nlm.nih.gov/28790390" }, { "database": "PubMed", "id": "28934129", "url": "https://pubmed.ncbi.nlm.nih.gov/28934129" }, { "database": "PubMed", "id": "29177868", "url": "https://pubmed.ncbi.nlm.nih.gov/29177868" }, { "database": "PubMed", "id": "29311680", "url": "https://pubmed.ncbi.nlm.nih.gov/29311680" }, { "database": "PubMed", "id": "29393871", "url": "https://pubmed.ncbi.nlm.nih.gov/29393871" }, { "database": "PubMed", "id": "29432553", "url": "https://pubmed.ncbi.nlm.nih.gov/29432553" }, { "database": "PubMed", "id": "29698741", "url": "https://pubmed.ncbi.nlm.nih.gov/29698741" }, { "database": "PubMed", "id": "29738527", "url": "https://pubmed.ncbi.nlm.nih.gov/29738527" }, { "database": "PubMed", "id": "30240640", "url": "https://pubmed.ncbi.nlm.nih.gov/30240640" }, { "database": "PubMed", "id": "30374127", "url": "https://pubmed.ncbi.nlm.nih.gov/30374127" }, { "database": "PubMed", "id": "30572687", "url": "https://pubmed.ncbi.nlm.nih.gov/30572687" }, { "database": "PubMed", "id": "31137828", "url": "https://pubmed.ncbi.nlm.nih.gov/31137828" }, { "database": "PubMed", "id": "31311314", "url": "https://pubmed.ncbi.nlm.nih.gov/31311314" }, { "database": "PubMed", "id": "31396538", "url": "https://pubmed.ncbi.nlm.nih.gov/31396538" }, { "database": "PubMed", "id": "32875583", "url": "https://pubmed.ncbi.nlm.nih.gov/32875583" }, { "database": "PubMed", "id": "33723215", "url": "https://pubmed.ncbi.nlm.nih.gov/33723215" }, { "database": "PubMed", "id": "35656886", "url": "https://pubmed.ncbi.nlm.nih.gov/35656886" }, { "database": "PubMed", "id": "18498745", "url": "https://pubmed.ncbi.nlm.nih.gov/18498745" } ], "site_lbl": "Ser307", "uniprot_canonical_ac": "P35568-1" } ], "record_id": "pubmed.12730242", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Reduced activation of phosphatidylinositol-3 kinase and increased serine 636 phosphorylation of insulin receptor substrate-1 in primary culture of skeletal muscle cells from patients with type 2 diabetes.", "journal": "Diabetes", "date": "2003", "authors": "Bouzakri K, Roques M, Gual P, Espinosa S, Guebre-Egziabher F, Riou JP, Laville M, Le Marchand-Brustel Y, Tanti JF, Vidal H", "reference": { "type": "PubMed", "id": "12765939", "url": "https://pubmed.ncbi.nlm.nih.gov/12765939" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 636, "end_pos": 636, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by RPS6KB1", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "16131083", "url": "https://pubmed.ncbi.nlm.nih.gov/16131083" }, { "database": "PubMed", "id": "19651622", "url": "https://pubmed.ncbi.nlm.nih.gov/19651622" }, { "database": "PubMed", "id": "16354680", "url": "https://pubmed.ncbi.nlm.nih.gov/16354680" }, { "database": "PubMed", "id": "11287630", "url": "https://pubmed.ncbi.nlm.nih.gov/11287630" }, { "database": "PubMed", "id": "12765939", "url": "https://pubmed.ncbi.nlm.nih.gov/12765939" }, { "database": "PubMed", "id": "14769130", "url": "https://pubmed.ncbi.nlm.nih.gov/14769130" }, { "database": "PubMed", "id": "15576463", "url": "https://pubmed.ncbi.nlm.nih.gov/15576463" }, { "database": "PubMed", "id": "16123357", "url": "https://pubmed.ncbi.nlm.nih.gov/16123357" }, { "database": "PubMed", "id": "16284649", "url": "https://pubmed.ncbi.nlm.nih.gov/16284649" }, { "database": "PubMed", "id": "17360977", "url": "https://pubmed.ncbi.nlm.nih.gov/17360977" }, { "database": "PubMed", "id": "17640984", "url": "https://pubmed.ncbi.nlm.nih.gov/17640984" }, { "database": "PubMed", "id": "18597775", "url": "https://pubmed.ncbi.nlm.nih.gov/18597775" }, { "database": "PubMed", "id": "18952604", "url": "https://pubmed.ncbi.nlm.nih.gov/18952604" }, { "database": "PubMed", "id": "19561084", "url": "https://pubmed.ncbi.nlm.nih.gov/19561084" }, { "database": "PubMed", "id": "19581421", "url": "https://pubmed.ncbi.nlm.nih.gov/19581421" }, { "database": "PubMed", "id": "20203102", "url": "https://pubmed.ncbi.nlm.nih.gov/20203102" }, { "database": "PubMed", "id": "21478152", "url": "https://pubmed.ncbi.nlm.nih.gov/21478152" }, { "database": "PubMed", "id": "21829658", "url": "https://pubmed.ncbi.nlm.nih.gov/21829658" }, { "database": "PubMed", "id": "22348058", "url": "https://pubmed.ncbi.nlm.nih.gov/22348058" }, { "database": "PubMed", "id": "22966072", "url": "https://pubmed.ncbi.nlm.nih.gov/22966072" }, { "database": "PubMed", "id": "23512499", "url": "https://pubmed.ncbi.nlm.nih.gov/23512499" }, { "database": "PubMed", "id": "25667991", "url": "https://pubmed.ncbi.nlm.nih.gov/25667991" }, { "database": "PubMed", "id": "25799226", "url": "https://pubmed.ncbi.nlm.nih.gov/25799226" }, { "database": "PubMed", "id": "25813876", "url": "https://pubmed.ncbi.nlm.nih.gov/25813876" }, { "database": "PubMed", "id": "26077338", "url": "https://pubmed.ncbi.nlm.nih.gov/26077338" }, { "database": "PubMed", "id": "27434075", "url": "https://pubmed.ncbi.nlm.nih.gov/27434075" }, { "database": "PubMed", "id": "28652303", "url": "https://pubmed.ncbi.nlm.nih.gov/28652303" }, { "database": "PubMed", "id": "28934129", "url": "https://pubmed.ncbi.nlm.nih.gov/28934129" }, { "database": "PubMed", "id": "30381640", "url": "https://pubmed.ncbi.nlm.nih.gov/30381640" }, { "database": "PubMed", "id": "36111162", "url": "https://pubmed.ncbi.nlm.nih.gov/36111162" }, { "database": "PubMed", "id": "18498745", "url": "https://pubmed.ncbi.nlm.nih.gov/18498745" }, { "database": "PubMed", "id": "17081983", "url": "https://pubmed.ncbi.nlm.nih.gov/17081983" } ], "site_lbl": "Ser636", "uniprot_canonical_ac": "P35568-1" } ], "record_id": "pubmed.12765939", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The Arg(972) variant in insulin receptor substrate-1 is associated with an atherogenic profile in offspring of type 2 diabetic patients.", "journal": "J. Clin. Endocrinol. Metab.", "date": "2003", "authors": "Marini Maria Adelaide, Frontoni Simona, Mineo Davide, Bracaglia Daniela, Cardellini Marina, De Nicolais Pierluigi, Baroni Alessandra, D'Alfonso Rossella, Perna Michela, Lauro Davide, Federici Massimo, Gambardella Sergio, Lauro Renato, Sesti Giorgio", "reference": { "type": "PubMed", "id": "12843189", "url": "https://pubmed.ncbi.nlm.nih.gov/12843189" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.12843189", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Cloning and increased expression of an insulin receptor substrate-1-like gene in human hepatocellular carcinoma.", "journal": "Biochem. Biophys. Res. Commun.", "date": "1992", "authors": "Nishiyama M, Wands J R", "reference": { "type": "PubMed", "id": "1311924", "url": "https://pubmed.ncbi.nlm.nih.gov/1311924" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.1311924", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Modulation of human insulin receptor substrate-1 tyrosine phosphorylation by protein kinase Cdelta.", "journal": "The Biochemical journal", "date": "2004", "authors": "Greene MW, Morrice N, Garofalo RS, Roth RA", "reference": { "type": "PubMed", "id": "14583092", "url": "https://pubmed.ncbi.nlm.nih.gov/14583092" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 307, "end_pos": 307, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by RPS6KB1", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "11160134", "url": "https://pubmed.ncbi.nlm.nih.gov/11160134" }, { "database": "PubMed", "id": "11606564", "url": "https://pubmed.ncbi.nlm.nih.gov/11606564" }, { "database": "PubMed", "id": "12409308", "url": "https://pubmed.ncbi.nlm.nih.gov/12409308" }, { "database": "PubMed", "id": "12714600", "url": "https://pubmed.ncbi.nlm.nih.gov/12714600" }, { "database": "PubMed", "id": "12730242", "url": "https://pubmed.ncbi.nlm.nih.gov/12730242" }, { "database": "PubMed", "id": "14556646", "url": "https://pubmed.ncbi.nlm.nih.gov/14556646" }, { "database": "PubMed", "id": "14583092", "url": "https://pubmed.ncbi.nlm.nih.gov/14583092" }, { "database": "PubMed", "id": "14641015", "url": "https://pubmed.ncbi.nlm.nih.gov/14641015" }, { "database": "PubMed", "id": "14697666", "url": "https://pubmed.ncbi.nlm.nih.gov/14697666" }, { "database": "PubMed", "id": "15020250", "url": "https://pubmed.ncbi.nlm.nih.gov/15020250" }, { "database": "PubMed", "id": "15153564", "url": "https://pubmed.ncbi.nlm.nih.gov/15153564" }, { "database": "PubMed", "id": "15582605", "url": "https://pubmed.ncbi.nlm.nih.gov/15582605" }, { "database": "PubMed", "id": "15802620", "url": "https://pubmed.ncbi.nlm.nih.gov/15802620" }, { "database": "PubMed", "id": "16046301", "url": "https://pubmed.ncbi.nlm.nih.gov/16046301" }, { "database": "PubMed", "id": "16055440", "url": "https://pubmed.ncbi.nlm.nih.gov/16055440" }, { "database": "PubMed", "id": "16099428", "url": "https://pubmed.ncbi.nlm.nih.gov/16099428" }, { "database": "PubMed", "id": "16210322", "url": "https://pubmed.ncbi.nlm.nih.gov/16210322" }, { "database": "PubMed", "id": "16269459", "url": "https://pubmed.ncbi.nlm.nih.gov/16269459" }, { "database": "PubMed", "id": "16516141", "url": "https://pubmed.ncbi.nlm.nih.gov/16516141" }, { "database": "PubMed", "id": "16754954", "url": "https://pubmed.ncbi.nlm.nih.gov/16754954" }, { "database": "PubMed", "id": "16839860", "url": "https://pubmed.ncbi.nlm.nih.gov/16839860" }, { "database": "PubMed", "id": "17077083", "url": "https://pubmed.ncbi.nlm.nih.gov/17077083" }, { "database": "PubMed", "id": "17095576", "url": "https://pubmed.ncbi.nlm.nih.gov/17095576" }, { "database": "PubMed", "id": "17276034", "url": "https://pubmed.ncbi.nlm.nih.gov/17276034" }, { "database": "PubMed", "id": "17481767", "url": "https://pubmed.ncbi.nlm.nih.gov/17481767" }, { "database": "PubMed", "id": "17575262", "url": "https://pubmed.ncbi.nlm.nih.gov/17575262" }, { "database": "PubMed", "id": "18187553", "url": "https://pubmed.ncbi.nlm.nih.gov/18187553" }, { "database": "PubMed", "id": "18372392", "url": "https://pubmed.ncbi.nlm.nih.gov/18372392" }, { "database": "PubMed", "id": "18380932", "url": "https://pubmed.ncbi.nlm.nih.gov/18380932" }, { "database": "PubMed", "id": "18496818", "url": "https://pubmed.ncbi.nlm.nih.gov/18496818" }, { "database": "PubMed", "id": "18952604", "url": "https://pubmed.ncbi.nlm.nih.gov/18952604" }, { "database": "PubMed", "id": "19095745", "url": "https://pubmed.ncbi.nlm.nih.gov/19095745" }, { "database": "PubMed", "id": "19524129", "url": "https://pubmed.ncbi.nlm.nih.gov/19524129" }, { "database": "PubMed", "id": "19897715", "url": "https://pubmed.ncbi.nlm.nih.gov/19897715" }, { "database": "PubMed", "id": "20351777", "url": "https://pubmed.ncbi.nlm.nih.gov/20351777" }, { "database": "PubMed", "id": "20382011", "url": "https://pubmed.ncbi.nlm.nih.gov/20382011" }, { "database": "PubMed", "id": "20384568", "url": "https://pubmed.ncbi.nlm.nih.gov/20384568" }, { "database": "PubMed", "id": "20541543", "url": "https://pubmed.ncbi.nlm.nih.gov/20541543" }, { "database": "PubMed", "id": "20587749", "url": "https://pubmed.ncbi.nlm.nih.gov/20587749" }, { "database": "PubMed", "id": "20594161", "url": "https://pubmed.ncbi.nlm.nih.gov/20594161" }, { "database": "PubMed", "id": "20594757", "url": "https://pubmed.ncbi.nlm.nih.gov/20594757" }, { "database": "PubMed", "id": "20702573", "url": "https://pubmed.ncbi.nlm.nih.gov/20702573" }, { "database": "PubMed", "id": "21119656", "url": "https://pubmed.ncbi.nlm.nih.gov/21119656" }, { "database": "PubMed", "id": "21478152", "url": "https://pubmed.ncbi.nlm.nih.gov/21478152" }, { "database": "PubMed", "id": "21505982", "url": "https://pubmed.ncbi.nlm.nih.gov/21505982" }, { "database": "PubMed", "id": "21786209", "url": "https://pubmed.ncbi.nlm.nih.gov/21786209" }, { "database": "PubMed", "id": "21852229", "url": "https://pubmed.ncbi.nlm.nih.gov/21852229" }, { "database": "PubMed", "id": "21900690", "url": "https://pubmed.ncbi.nlm.nih.gov/21900690" }, { "database": "PubMed", "id": "22046423", "url": "https://pubmed.ncbi.nlm.nih.gov/22046423" }, { "database": "PubMed", "id": "22227580", "url": "https://pubmed.ncbi.nlm.nih.gov/22227580" }, { "database": "PubMed", "id": "22266116", "url": "https://pubmed.ncbi.nlm.nih.gov/22266116" }, { "database": "PubMed", "id": "22328823", "url": "https://pubmed.ncbi.nlm.nih.gov/22328823" }, { "database": "PubMed", "id": "22348058", "url": "https://pubmed.ncbi.nlm.nih.gov/22348058" }, { "database": "PubMed", "id": "22491740", "url": "https://pubmed.ncbi.nlm.nih.gov/22491740" }, { "database": "PubMed", "id": "22728372", "url": "https://pubmed.ncbi.nlm.nih.gov/22728372" }, { "database": "PubMed", "id": "22766331", "url": "https://pubmed.ncbi.nlm.nih.gov/22766331" }, { "database": "PubMed", "id": "23095254", "url": "https://pubmed.ncbi.nlm.nih.gov/23095254" }, { "database": "PubMed", "id": "23174405", "url": "https://pubmed.ncbi.nlm.nih.gov/23174405" }, { "database": "PubMed", "id": "23182460", "url": "https://pubmed.ncbi.nlm.nih.gov/23182460" }, { "database": "PubMed", "id": "23481042", "url": "https://pubmed.ncbi.nlm.nih.gov/23481042" }, { "database": "PubMed", "id": "23566306", "url": "https://pubmed.ncbi.nlm.nih.gov/23566306" }, { "database": "PubMed", "id": "23592917", "url": "https://pubmed.ncbi.nlm.nih.gov/23592917" }, { "database": "PubMed", "id": "23891856", "url": "https://pubmed.ncbi.nlm.nih.gov/23891856" }, { "database": "PubMed", "id": "23958494", "url": "https://pubmed.ncbi.nlm.nih.gov/23958494" }, { "database": "PubMed", "id": "24068326", "url": "https://pubmed.ncbi.nlm.nih.gov/24068326" }, { "database": "PubMed", "id": "24846082", "url": "https://pubmed.ncbi.nlm.nih.gov/24846082" }, { "database": "PubMed", "id": "25120613", "url": "https://pubmed.ncbi.nlm.nih.gov/25120613" }, { "database": "PubMed", "id": "25355439", "url": "https://pubmed.ncbi.nlm.nih.gov/25355439" }, { "database": "PubMed", "id": "25645159", "url": "https://pubmed.ncbi.nlm.nih.gov/25645159" }, { "database": "PubMed", "id": "25799226", "url": "https://pubmed.ncbi.nlm.nih.gov/25799226" }, { "database": "PubMed", "id": "26604643", "url": "https://pubmed.ncbi.nlm.nih.gov/26604643" }, { "database": "PubMed", "id": "26698173", "url": "https://pubmed.ncbi.nlm.nih.gov/26698173" }, { "database": "PubMed", "id": "26704265", "url": "https://pubmed.ncbi.nlm.nih.gov/26704265" }, { "database": "PubMed", "id": "26899161", "url": "https://pubmed.ncbi.nlm.nih.gov/26899161" }, { "database": "PubMed", "id": "26983645", "url": "https://pubmed.ncbi.nlm.nih.gov/26983645" }, { "database": "PubMed", "id": "27222060", "url": "https://pubmed.ncbi.nlm.nih.gov/27222060" }, { "database": "PubMed", "id": "27506476", "url": "https://pubmed.ncbi.nlm.nih.gov/27506476" }, { "database": "PubMed", "id": "27544192", "url": "https://pubmed.ncbi.nlm.nih.gov/27544192" }, { "database": "PubMed", "id": "27686967", "url": "https://pubmed.ncbi.nlm.nih.gov/27686967" }, { "database": "PubMed", "id": "27936435", "url": "https://pubmed.ncbi.nlm.nih.gov/27936435" }, { "database": "PubMed", "id": "28161417", "url": "https://pubmed.ncbi.nlm.nih.gov/28161417" }, { "database": "PubMed", "id": "28656239", "url": "https://pubmed.ncbi.nlm.nih.gov/28656239" }, { "database": "PubMed", "id": "28731188", "url": "https://pubmed.ncbi.nlm.nih.gov/28731188" }, { "database": "PubMed", "id": "28790390", "url": "https://pubmed.ncbi.nlm.nih.gov/28790390" }, { "database": "PubMed", "id": "28934129", "url": "https://pubmed.ncbi.nlm.nih.gov/28934129" }, { "database": "PubMed", "id": "29177868", "url": "https://pubmed.ncbi.nlm.nih.gov/29177868" }, { "database": "PubMed", "id": "29311680", "url": "https://pubmed.ncbi.nlm.nih.gov/29311680" }, { "database": "PubMed", "id": "29393871", "url": "https://pubmed.ncbi.nlm.nih.gov/29393871" }, { "database": "PubMed", "id": "29432553", "url": "https://pubmed.ncbi.nlm.nih.gov/29432553" }, { "database": "PubMed", "id": "29698741", "url": "https://pubmed.ncbi.nlm.nih.gov/29698741" }, { "database": "PubMed", "id": "29738527", "url": "https://pubmed.ncbi.nlm.nih.gov/29738527" }, { "database": "PubMed", "id": "30240640", "url": "https://pubmed.ncbi.nlm.nih.gov/30240640" }, { "database": "PubMed", "id": "30374127", "url": "https://pubmed.ncbi.nlm.nih.gov/30374127" }, { "database": "PubMed", "id": "30572687", "url": "https://pubmed.ncbi.nlm.nih.gov/30572687" }, { "database": "PubMed", "id": "31137828", "url": "https://pubmed.ncbi.nlm.nih.gov/31137828" }, { "database": "PubMed", "id": "31311314", "url": "https://pubmed.ncbi.nlm.nih.gov/31311314" }, { "database": "PubMed", "id": "31396538", "url": "https://pubmed.ncbi.nlm.nih.gov/31396538" }, { "database": "PubMed", "id": "32875583", "url": "https://pubmed.ncbi.nlm.nih.gov/32875583" }, { "database": "PubMed", "id": "33723215", "url": "https://pubmed.ncbi.nlm.nih.gov/33723215" }, { "database": "PubMed", "id": "35656886", "url": "https://pubmed.ncbi.nlm.nih.gov/35656886" }, { "database": "PubMed", "id": "18498745", "url": "https://pubmed.ncbi.nlm.nih.gov/18498745" } ], "site_lbl": "Ser307", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 323, "end_pos": 323, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "PubMed", "id": "24275569", "url": "https://pubmed.ncbi.nlm.nih.gov/24275569" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "14583092", "url": "https://pubmed.ncbi.nlm.nih.gov/14583092" } ], "site_lbl": "Ser323", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 362, "end_pos": 362, "kinase_uniprot_canonical_ac": "Q05655-1", "kinase_gene_name": "PRKCD", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "14583092", "url": "https://pubmed.ncbi.nlm.nih.gov/14583092" }, { "database": "PubMed", "id": "18285345", "url": "https://pubmed.ncbi.nlm.nih.gov/18285345" } ], "site_lbl": "Ser362", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 574, "end_pos": 574, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "16131083", "url": "https://pubmed.ncbi.nlm.nih.gov/16131083" }, { "database": "PubMed", "id": "14583092", "url": "https://pubmed.ncbi.nlm.nih.gov/14583092" } ], "site_lbl": "Ser574", "uniprot_canonical_ac": "P35568-1" } ], "record_id": "pubmed.14583092", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 4 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Locating a protein-protein interaction in living cells via split Renilla luciferase complementation.", "journal": "Analytical chemistry", "date": "2003-08-15", "authors": "Kaihara Asami, Kawai Yasutoshi, Sato Moritoshi, Ozawa Takeaki, Umezawa Yoshio", "reference": { "type": "PubMed", "id": "14632132", "url": "https://pubmed.ncbi.nlm.nih.gov/14632132" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 941, "end_pos": 941, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by INSR", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "12220227", "url": "https://pubmed.ncbi.nlm.nih.gov/12220227" }, { "database": "IntAct", "id": "P35568", "url": "https://www.ebi.ac.uk/intact/interactors/id:P35568*" }, { "database": "PubMed", "id": "14632132", "url": "https://pubmed.ncbi.nlm.nih.gov/14632132" }, { "database": "PubMed", "id": "11403293", "url": "https://pubmed.ncbi.nlm.nih.gov/11403293" }, { "database": "PRO", "id": "P35568", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=P35568" }, { "database": "PubMed", "id": "20685959", "url": "https://pubmed.ncbi.nlm.nih.gov/20685959" }, { "database": "PubMed", "id": "22617042", "url": "https://pubmed.ncbi.nlm.nih.gov/22617042" }, { "database": "PubMed", "id": "25299696", "url": "https://pubmed.ncbi.nlm.nih.gov/25299696" }, { "database": "PubMed", "id": "26378251", "url": "https://pubmed.ncbi.nlm.nih.gov/26378251" } ], "site_lbl": "Tyr941", "uniprot_canonical_ac": "P35568-1" } ], "record_id": "pubmed.14632132", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Fatty acid-induced insulin resistance: role of insulin receptor substrate 1 serine phosphorylation in the retroregulation of insulin signalling.", "journal": "Biochemical Society transactions", "date": "2003", "authors": "Le Marchand-Brustel Y, Gual P, Gremeaux T, Gonzalez T, Barres R, Tanti JF", "reference": { "type": "PubMed", "id": "14641015", "url": "https://pubmed.ncbi.nlm.nih.gov/14641015" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 307, "end_pos": 307, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by RPS6KB1", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "11160134", "url": "https://pubmed.ncbi.nlm.nih.gov/11160134" }, { "database": "PubMed", "id": "11606564", "url": "https://pubmed.ncbi.nlm.nih.gov/11606564" }, { "database": "PubMed", "id": "12409308", "url": "https://pubmed.ncbi.nlm.nih.gov/12409308" }, { "database": "PubMed", "id": "12714600", "url": "https://pubmed.ncbi.nlm.nih.gov/12714600" }, { "database": "PubMed", "id": "12730242", "url": "https://pubmed.ncbi.nlm.nih.gov/12730242" }, { "database": "PubMed", "id": "14556646", "url": "https://pubmed.ncbi.nlm.nih.gov/14556646" }, { "database": "PubMed", "id": "14583092", "url": "https://pubmed.ncbi.nlm.nih.gov/14583092" }, { "database": "PubMed", "id": "14641015", "url": "https://pubmed.ncbi.nlm.nih.gov/14641015" }, { "database": "PubMed", "id": "14697666", "url": "https://pubmed.ncbi.nlm.nih.gov/14697666" }, { "database": "PubMed", "id": "15020250", "url": "https://pubmed.ncbi.nlm.nih.gov/15020250" }, { "database": "PubMed", "id": "15153564", "url": "https://pubmed.ncbi.nlm.nih.gov/15153564" }, { "database": "PubMed", "id": "15582605", "url": "https://pubmed.ncbi.nlm.nih.gov/15582605" }, { "database": "PubMed", "id": "15802620", "url": "https://pubmed.ncbi.nlm.nih.gov/15802620" }, { "database": "PubMed", "id": "16046301", "url": "https://pubmed.ncbi.nlm.nih.gov/16046301" }, { "database": "PubMed", "id": "16055440", "url": "https://pubmed.ncbi.nlm.nih.gov/16055440" }, { "database": "PubMed", "id": "16099428", "url": "https://pubmed.ncbi.nlm.nih.gov/16099428" }, { "database": "PubMed", "id": "16210322", "url": "https://pubmed.ncbi.nlm.nih.gov/16210322" }, { "database": "PubMed", "id": "16269459", "url": "https://pubmed.ncbi.nlm.nih.gov/16269459" }, { "database": "PubMed", "id": "16516141", "url": "https://pubmed.ncbi.nlm.nih.gov/16516141" }, { "database": "PubMed", "id": "16754954", "url": "https://pubmed.ncbi.nlm.nih.gov/16754954" }, { "database": "PubMed", "id": "16839860", "url": "https://pubmed.ncbi.nlm.nih.gov/16839860" }, { "database": "PubMed", "id": "17077083", "url": "https://pubmed.ncbi.nlm.nih.gov/17077083" }, { "database": "PubMed", "id": "17095576", "url": "https://pubmed.ncbi.nlm.nih.gov/17095576" }, { "database": "PubMed", "id": "17276034", "url": "https://pubmed.ncbi.nlm.nih.gov/17276034" }, { "database": "PubMed", "id": "17481767", "url": "https://pubmed.ncbi.nlm.nih.gov/17481767" }, { "database": "PubMed", "id": "17575262", "url": "https://pubmed.ncbi.nlm.nih.gov/17575262" }, { "database": "PubMed", "id": "18187553", "url": "https://pubmed.ncbi.nlm.nih.gov/18187553" }, { "database": "PubMed", "id": "18372392", "url": "https://pubmed.ncbi.nlm.nih.gov/18372392" }, { "database": "PubMed", "id": "18380932", "url": "https://pubmed.ncbi.nlm.nih.gov/18380932" }, { "database": "PubMed", "id": "18496818", "url": "https://pubmed.ncbi.nlm.nih.gov/18496818" }, { "database": "PubMed", "id": "18952604", "url": "https://pubmed.ncbi.nlm.nih.gov/18952604" }, { "database": "PubMed", "id": "19095745", "url": "https://pubmed.ncbi.nlm.nih.gov/19095745" }, { "database": "PubMed", "id": "19524129", "url": "https://pubmed.ncbi.nlm.nih.gov/19524129" }, { "database": "PubMed", "id": "19897715", "url": "https://pubmed.ncbi.nlm.nih.gov/19897715" }, { "database": "PubMed", "id": "20351777", "url": "https://pubmed.ncbi.nlm.nih.gov/20351777" }, { "database": "PubMed", "id": "20382011", "url": "https://pubmed.ncbi.nlm.nih.gov/20382011" }, { "database": "PubMed", "id": "20384568", "url": "https://pubmed.ncbi.nlm.nih.gov/20384568" }, { "database": "PubMed", "id": "20541543", "url": "https://pubmed.ncbi.nlm.nih.gov/20541543" }, { "database": "PubMed", "id": "20587749", "url": "https://pubmed.ncbi.nlm.nih.gov/20587749" }, { "database": "PubMed", "id": "20594161", "url": "https://pubmed.ncbi.nlm.nih.gov/20594161" }, { "database": "PubMed", "id": "20594757", "url": "https://pubmed.ncbi.nlm.nih.gov/20594757" }, { "database": "PubMed", "id": "20702573", "url": "https://pubmed.ncbi.nlm.nih.gov/20702573" }, { "database": "PubMed", "id": "21119656", "url": "https://pubmed.ncbi.nlm.nih.gov/21119656" }, { "database": "PubMed", "id": "21478152", "url": "https://pubmed.ncbi.nlm.nih.gov/21478152" }, { "database": "PubMed", "id": "21505982", "url": "https://pubmed.ncbi.nlm.nih.gov/21505982" }, { "database": "PubMed", "id": "21786209", "url": "https://pubmed.ncbi.nlm.nih.gov/21786209" }, { "database": "PubMed", "id": "21852229", "url": "https://pubmed.ncbi.nlm.nih.gov/21852229" }, { "database": "PubMed", "id": "21900690", "url": "https://pubmed.ncbi.nlm.nih.gov/21900690" }, { "database": "PubMed", "id": "22046423", "url": "https://pubmed.ncbi.nlm.nih.gov/22046423" }, { "database": "PubMed", "id": "22227580", "url": "https://pubmed.ncbi.nlm.nih.gov/22227580" }, { "database": "PubMed", "id": "22266116", "url": "https://pubmed.ncbi.nlm.nih.gov/22266116" }, { "database": "PubMed", "id": "22328823", "url": "https://pubmed.ncbi.nlm.nih.gov/22328823" }, { "database": "PubMed", "id": "22348058", "url": "https://pubmed.ncbi.nlm.nih.gov/22348058" }, { "database": "PubMed", "id": "22491740", "url": "https://pubmed.ncbi.nlm.nih.gov/22491740" }, { "database": "PubMed", "id": "22728372", "url": "https://pubmed.ncbi.nlm.nih.gov/22728372" }, { "database": "PubMed", "id": "22766331", "url": "https://pubmed.ncbi.nlm.nih.gov/22766331" }, { "database": "PubMed", "id": "23095254", "url": "https://pubmed.ncbi.nlm.nih.gov/23095254" }, { "database": "PubMed", "id": "23174405", "url": "https://pubmed.ncbi.nlm.nih.gov/23174405" }, { "database": "PubMed", "id": "23182460", "url": "https://pubmed.ncbi.nlm.nih.gov/23182460" }, { "database": "PubMed", "id": "23481042", "url": "https://pubmed.ncbi.nlm.nih.gov/23481042" }, { "database": "PubMed", "id": "23566306", "url": "https://pubmed.ncbi.nlm.nih.gov/23566306" }, { "database": "PubMed", "id": "23592917", "url": "https://pubmed.ncbi.nlm.nih.gov/23592917" }, { "database": "PubMed", "id": "23891856", "url": "https://pubmed.ncbi.nlm.nih.gov/23891856" }, { "database": "PubMed", "id": "23958494", "url": "https://pubmed.ncbi.nlm.nih.gov/23958494" }, { "database": "PubMed", "id": "24068326", "url": "https://pubmed.ncbi.nlm.nih.gov/24068326" }, { "database": "PubMed", "id": "24846082", "url": "https://pubmed.ncbi.nlm.nih.gov/24846082" }, { "database": "PubMed", "id": "25120613", "url": "https://pubmed.ncbi.nlm.nih.gov/25120613" }, { "database": "PubMed", "id": "25355439", "url": "https://pubmed.ncbi.nlm.nih.gov/25355439" }, { "database": "PubMed", "id": "25645159", "url": "https://pubmed.ncbi.nlm.nih.gov/25645159" }, { "database": "PubMed", "id": "25799226", "url": "https://pubmed.ncbi.nlm.nih.gov/25799226" }, { "database": "PubMed", "id": "26604643", "url": "https://pubmed.ncbi.nlm.nih.gov/26604643" }, { "database": "PubMed", "id": "26698173", "url": "https://pubmed.ncbi.nlm.nih.gov/26698173" }, { "database": "PubMed", "id": "26704265", "url": "https://pubmed.ncbi.nlm.nih.gov/26704265" }, { "database": "PubMed", "id": "26899161", "url": "https://pubmed.ncbi.nlm.nih.gov/26899161" }, { "database": "PubMed", "id": "26983645", "url": "https://pubmed.ncbi.nlm.nih.gov/26983645" }, { "database": "PubMed", "id": "27222060", "url": "https://pubmed.ncbi.nlm.nih.gov/27222060" }, { "database": "PubMed", "id": "27506476", "url": "https://pubmed.ncbi.nlm.nih.gov/27506476" }, { "database": "PubMed", "id": "27544192", "url": "https://pubmed.ncbi.nlm.nih.gov/27544192" }, { "database": "PubMed", "id": "27686967", "url": "https://pubmed.ncbi.nlm.nih.gov/27686967" }, { "database": "PubMed", "id": "27936435", "url": "https://pubmed.ncbi.nlm.nih.gov/27936435" }, { "database": "PubMed", "id": "28161417", "url": "https://pubmed.ncbi.nlm.nih.gov/28161417" }, { "database": "PubMed", "id": "28656239", "url": "https://pubmed.ncbi.nlm.nih.gov/28656239" }, { "database": "PubMed", "id": "28731188", "url": "https://pubmed.ncbi.nlm.nih.gov/28731188" }, { "database": "PubMed", "id": "28790390", "url": "https://pubmed.ncbi.nlm.nih.gov/28790390" }, { "database": "PubMed", "id": "28934129", "url": "https://pubmed.ncbi.nlm.nih.gov/28934129" }, { "database": "PubMed", "id": "29177868", "url": "https://pubmed.ncbi.nlm.nih.gov/29177868" }, { "database": "PubMed", "id": "29311680", "url": "https://pubmed.ncbi.nlm.nih.gov/29311680" }, { "database": "PubMed", "id": "29393871", "url": "https://pubmed.ncbi.nlm.nih.gov/29393871" }, { "database": "PubMed", "id": "29432553", "url": "https://pubmed.ncbi.nlm.nih.gov/29432553" }, { "database": "PubMed", "id": "29698741", "url": "https://pubmed.ncbi.nlm.nih.gov/29698741" }, { "database": "PubMed", "id": "29738527", "url": "https://pubmed.ncbi.nlm.nih.gov/29738527" }, { "database": "PubMed", "id": "30240640", "url": "https://pubmed.ncbi.nlm.nih.gov/30240640" }, { "database": "PubMed", "id": "30374127", "url": "https://pubmed.ncbi.nlm.nih.gov/30374127" }, { "database": "PubMed", "id": "30572687", "url": "https://pubmed.ncbi.nlm.nih.gov/30572687" }, { "database": "PubMed", "id": "31137828", "url": "https://pubmed.ncbi.nlm.nih.gov/31137828" }, { "database": "PubMed", "id": "31311314", "url": "https://pubmed.ncbi.nlm.nih.gov/31311314" }, { "database": "PubMed", "id": "31396538", "url": "https://pubmed.ncbi.nlm.nih.gov/31396538" }, { "database": "PubMed", "id": "32875583", "url": "https://pubmed.ncbi.nlm.nih.gov/32875583" }, { "database": "PubMed", "id": "33723215", "url": "https://pubmed.ncbi.nlm.nih.gov/33723215" }, { "database": "PubMed", "id": "35656886", "url": "https://pubmed.ncbi.nlm.nih.gov/35656886" }, { "database": "PubMed", "id": "18498745", "url": "https://pubmed.ncbi.nlm.nih.gov/18498745" } ], "site_lbl": "Ser307", "uniprot_canonical_ac": "P35568-1" } ], "record_id": "pubmed.14641015", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Genetic polymorphism PC-1 K121Q and ethnic susceptibility to insulin resistance.", "journal": "J. Clin. Endocrinol. Metab.", "date": "2003", "authors": "Abate Nicola, Carulli Lucia, Cabo-Chan Alberto, Chandalia Manisha, Snell Peter G, Grundy Scott M", "reference": { "type": "PubMed", "id": "14671192", "url": "https://pubmed.ncbi.nlm.nih.gov/14671192" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.14671192", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Glutamate excitotoxicity attenuates insulin-like growth factor-I prosurvival signaling.", "journal": "Molecular and cellular neurosciences", "date": "2003", "authors": "Garcia-Galloway E, Arango C, Pons S, Torres-Aleman I", "reference": { "type": "PubMed", "id": "14697666", "url": "https://pubmed.ncbi.nlm.nih.gov/14697666" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 307, "end_pos": 307, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by RPS6KB1", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "11160134", "url": "https://pubmed.ncbi.nlm.nih.gov/11160134" }, { "database": "PubMed", "id": "11606564", "url": "https://pubmed.ncbi.nlm.nih.gov/11606564" }, { "database": "PubMed", "id": "12409308", "url": "https://pubmed.ncbi.nlm.nih.gov/12409308" }, { "database": "PubMed", "id": "12714600", "url": "https://pubmed.ncbi.nlm.nih.gov/12714600" }, { "database": "PubMed", "id": "12730242", "url": "https://pubmed.ncbi.nlm.nih.gov/12730242" }, { "database": "PubMed", "id": "14556646", "url": "https://pubmed.ncbi.nlm.nih.gov/14556646" }, { "database": "PubMed", "id": "14583092", "url": "https://pubmed.ncbi.nlm.nih.gov/14583092" }, { "database": "PubMed", "id": "14641015", "url": "https://pubmed.ncbi.nlm.nih.gov/14641015" }, { "database": "PubMed", "id": "14697666", "url": "https://pubmed.ncbi.nlm.nih.gov/14697666" }, { "database": "PubMed", "id": "15020250", "url": "https://pubmed.ncbi.nlm.nih.gov/15020250" }, { "database": "PubMed", "id": "15153564", "url": "https://pubmed.ncbi.nlm.nih.gov/15153564" }, { "database": "PubMed", "id": "15582605", "url": "https://pubmed.ncbi.nlm.nih.gov/15582605" }, { "database": "PubMed", "id": "15802620", "url": "https://pubmed.ncbi.nlm.nih.gov/15802620" }, { "database": "PubMed", "id": "16046301", "url": "https://pubmed.ncbi.nlm.nih.gov/16046301" }, { "database": "PubMed", "id": "16055440", "url": "https://pubmed.ncbi.nlm.nih.gov/16055440" }, { "database": "PubMed", "id": "16099428", "url": "https://pubmed.ncbi.nlm.nih.gov/16099428" }, { "database": "PubMed", "id": "16210322", "url": "https://pubmed.ncbi.nlm.nih.gov/16210322" }, { "database": "PubMed", "id": "16269459", "url": "https://pubmed.ncbi.nlm.nih.gov/16269459" }, { "database": "PubMed", "id": "16516141", "url": "https://pubmed.ncbi.nlm.nih.gov/16516141" }, { "database": "PubMed", "id": "16754954", "url": "https://pubmed.ncbi.nlm.nih.gov/16754954" }, { "database": "PubMed", "id": "16839860", "url": "https://pubmed.ncbi.nlm.nih.gov/16839860" }, { "database": "PubMed", "id": "17077083", "url": "https://pubmed.ncbi.nlm.nih.gov/17077083" }, { "database": "PubMed", "id": "17095576", "url": "https://pubmed.ncbi.nlm.nih.gov/17095576" }, { "database": "PubMed", "id": "17276034", "url": "https://pubmed.ncbi.nlm.nih.gov/17276034" }, { "database": "PubMed", "id": "17481767", "url": "https://pubmed.ncbi.nlm.nih.gov/17481767" }, { "database": "PubMed", "id": "17575262", "url": "https://pubmed.ncbi.nlm.nih.gov/17575262" }, { "database": "PubMed", "id": "18187553", "url": "https://pubmed.ncbi.nlm.nih.gov/18187553" }, { "database": "PubMed", "id": "18372392", "url": "https://pubmed.ncbi.nlm.nih.gov/18372392" }, { "database": "PubMed", "id": "18380932", "url": "https://pubmed.ncbi.nlm.nih.gov/18380932" }, { "database": "PubMed", "id": "18496818", "url": "https://pubmed.ncbi.nlm.nih.gov/18496818" }, { "database": "PubMed", "id": "18952604", "url": "https://pubmed.ncbi.nlm.nih.gov/18952604" }, { "database": "PubMed", "id": "19095745", "url": "https://pubmed.ncbi.nlm.nih.gov/19095745" }, { "database": "PubMed", "id": "19524129", "url": "https://pubmed.ncbi.nlm.nih.gov/19524129" }, { "database": "PubMed", "id": "19897715", "url": "https://pubmed.ncbi.nlm.nih.gov/19897715" }, { "database": "PubMed", "id": "20351777", "url": "https://pubmed.ncbi.nlm.nih.gov/20351777" }, { "database": "PubMed", "id": "20382011", "url": "https://pubmed.ncbi.nlm.nih.gov/20382011" }, { "database": "PubMed", "id": "20384568", "url": "https://pubmed.ncbi.nlm.nih.gov/20384568" }, { "database": "PubMed", "id": "20541543", "url": "https://pubmed.ncbi.nlm.nih.gov/20541543" }, { "database": "PubMed", "id": "20587749", "url": "https://pubmed.ncbi.nlm.nih.gov/20587749" }, { "database": "PubMed", "id": "20594161", "url": "https://pubmed.ncbi.nlm.nih.gov/20594161" }, { "database": "PubMed", "id": "20594757", "url": "https://pubmed.ncbi.nlm.nih.gov/20594757" }, { "database": "PubMed", "id": "20702573", "url": "https://pubmed.ncbi.nlm.nih.gov/20702573" }, { "database": "PubMed", "id": "21119656", "url": "https://pubmed.ncbi.nlm.nih.gov/21119656" }, { "database": "PubMed", "id": "21478152", "url": "https://pubmed.ncbi.nlm.nih.gov/21478152" }, { "database": "PubMed", "id": "21505982", "url": "https://pubmed.ncbi.nlm.nih.gov/21505982" }, { "database": "PubMed", "id": "21786209", "url": "https://pubmed.ncbi.nlm.nih.gov/21786209" }, { "database": "PubMed", "id": "21852229", "url": "https://pubmed.ncbi.nlm.nih.gov/21852229" }, { "database": "PubMed", "id": "21900690", "url": "https://pubmed.ncbi.nlm.nih.gov/21900690" }, { "database": "PubMed", "id": "22046423", "url": "https://pubmed.ncbi.nlm.nih.gov/22046423" }, { "database": "PubMed", "id": "22227580", "url": "https://pubmed.ncbi.nlm.nih.gov/22227580" }, { "database": "PubMed", "id": "22266116", "url": "https://pubmed.ncbi.nlm.nih.gov/22266116" }, { "database": "PubMed", "id": "22328823", "url": "https://pubmed.ncbi.nlm.nih.gov/22328823" }, { "database": "PubMed", "id": "22348058", "url": "https://pubmed.ncbi.nlm.nih.gov/22348058" }, { "database": "PubMed", "id": "22491740", "url": "https://pubmed.ncbi.nlm.nih.gov/22491740" }, { "database": "PubMed", "id": "22728372", "url": "https://pubmed.ncbi.nlm.nih.gov/22728372" }, { "database": "PubMed", "id": "22766331", "url": "https://pubmed.ncbi.nlm.nih.gov/22766331" }, { "database": "PubMed", "id": "23095254", "url": "https://pubmed.ncbi.nlm.nih.gov/23095254" }, { "database": "PubMed", "id": "23174405", "url": "https://pubmed.ncbi.nlm.nih.gov/23174405" }, { "database": "PubMed", "id": "23182460", "url": "https://pubmed.ncbi.nlm.nih.gov/23182460" }, { "database": "PubMed", "id": "23481042", "url": "https://pubmed.ncbi.nlm.nih.gov/23481042" }, { "database": "PubMed", "id": "23566306", "url": "https://pubmed.ncbi.nlm.nih.gov/23566306" }, { "database": "PubMed", "id": "23592917", "url": "https://pubmed.ncbi.nlm.nih.gov/23592917" }, { "database": "PubMed", "id": "23891856", "url": "https://pubmed.ncbi.nlm.nih.gov/23891856" }, { "database": "PubMed", "id": "23958494", "url": "https://pubmed.ncbi.nlm.nih.gov/23958494" }, { "database": "PubMed", "id": "24068326", "url": "https://pubmed.ncbi.nlm.nih.gov/24068326" }, { "database": "PubMed", "id": "24846082", "url": "https://pubmed.ncbi.nlm.nih.gov/24846082" }, { "database": "PubMed", "id": "25120613", "url": "https://pubmed.ncbi.nlm.nih.gov/25120613" }, { "database": "PubMed", "id": "25355439", "url": "https://pubmed.ncbi.nlm.nih.gov/25355439" }, { "database": "PubMed", "id": "25645159", "url": "https://pubmed.ncbi.nlm.nih.gov/25645159" }, { "database": "PubMed", "id": "25799226", "url": "https://pubmed.ncbi.nlm.nih.gov/25799226" }, { "database": "PubMed", "id": "26604643", "url": "https://pubmed.ncbi.nlm.nih.gov/26604643" }, { "database": "PubMed", "id": "26698173", "url": "https://pubmed.ncbi.nlm.nih.gov/26698173" }, { "database": "PubMed", "id": "26704265", "url": "https://pubmed.ncbi.nlm.nih.gov/26704265" }, { "database": "PubMed", "id": "26899161", "url": "https://pubmed.ncbi.nlm.nih.gov/26899161" }, { "database": "PubMed", "id": "26983645", "url": "https://pubmed.ncbi.nlm.nih.gov/26983645" }, { "database": "PubMed", "id": "27222060", "url": "https://pubmed.ncbi.nlm.nih.gov/27222060" }, { "database": "PubMed", "id": "27506476", "url": "https://pubmed.ncbi.nlm.nih.gov/27506476" }, { "database": "PubMed", "id": "27544192", "url": "https://pubmed.ncbi.nlm.nih.gov/27544192" }, { "database": "PubMed", "id": "27686967", "url": "https://pubmed.ncbi.nlm.nih.gov/27686967" }, { "database": "PubMed", "id": "27936435", "url": "https://pubmed.ncbi.nlm.nih.gov/27936435" }, { "database": "PubMed", "id": "28161417", "url": "https://pubmed.ncbi.nlm.nih.gov/28161417" }, { "database": "PubMed", "id": "28656239", "url": "https://pubmed.ncbi.nlm.nih.gov/28656239" }, { "database": "PubMed", "id": "28731188", "url": "https://pubmed.ncbi.nlm.nih.gov/28731188" }, { "database": "PubMed", "id": "28790390", "url": "https://pubmed.ncbi.nlm.nih.gov/28790390" }, { "database": "PubMed", "id": "28934129", "url": "https://pubmed.ncbi.nlm.nih.gov/28934129" }, { "database": "PubMed", "id": "29177868", "url": "https://pubmed.ncbi.nlm.nih.gov/29177868" }, { "database": "PubMed", "id": "29311680", "url": "https://pubmed.ncbi.nlm.nih.gov/29311680" }, { "database": "PubMed", "id": "29393871", "url": "https://pubmed.ncbi.nlm.nih.gov/29393871" }, { "database": "PubMed", "id": "29432553", "url": "https://pubmed.ncbi.nlm.nih.gov/29432553" }, { "database": "PubMed", "id": "29698741", "url": "https://pubmed.ncbi.nlm.nih.gov/29698741" }, { "database": "PubMed", "id": "29738527", "url": "https://pubmed.ncbi.nlm.nih.gov/29738527" }, { "database": "PubMed", "id": "30240640", "url": "https://pubmed.ncbi.nlm.nih.gov/30240640" }, { "database": "PubMed", "id": "30374127", "url": "https://pubmed.ncbi.nlm.nih.gov/30374127" }, { "database": "PubMed", "id": "30572687", "url": "https://pubmed.ncbi.nlm.nih.gov/30572687" }, { "database": "PubMed", "id": "31137828", "url": "https://pubmed.ncbi.nlm.nih.gov/31137828" }, { "database": "PubMed", "id": "31311314", "url": "https://pubmed.ncbi.nlm.nih.gov/31311314" }, { "database": "PubMed", "id": "31396538", "url": "https://pubmed.ncbi.nlm.nih.gov/31396538" }, { "database": "PubMed", "id": "32875583", "url": "https://pubmed.ncbi.nlm.nih.gov/32875583" }, { "database": "PubMed", "id": "33723215", "url": "https://pubmed.ncbi.nlm.nih.gov/33723215" }, { "database": "PubMed", "id": "35656886", "url": "https://pubmed.ncbi.nlm.nih.gov/35656886" }, { "database": "PubMed", "id": "18498745", "url": "https://pubmed.ncbi.nlm.nih.gov/18498745" } ], "site_lbl": "Ser307", "uniprot_canonical_ac": "P35568-1" } ], "record_id": "pubmed.14697666", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "G972R IRS-1 variant impairs insulin regulation of endothelial nitric oxide synthase in cultured human endothelial cells.", "journal": "Circulation", "date": "2004", "authors": "Federici Massimo, Pandolfi Assunta, De Filippis Elena Anna, Pellegrini Giuliana, Menghini Rossella, Lauro Davide, Cardellini Marina, Romano Mario, Sesti Giorgio, Lauro Renato, Consoli Agostino", "reference": { "type": "PubMed", "id": "14707024", "url": "https://pubmed.ncbi.nlm.nih.gov/14707024" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.14707024", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Muscarinic-receptor-mediated inhibition of insulin-like growth factor-1 receptor-stimulated phosphoinositide 3-kinase signalling in 1321N1 astrocytoma cells.", "journal": "The Biochemical journal", "date": "2004", "authors": "Batty IH, Fleming IN, Downes CP", "reference": { "type": "PubMed", "id": "14769130", "url": "https://pubmed.ncbi.nlm.nih.gov/14769130" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 312, "end_pos": 312, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by IKKB, MAPK8 and RPS6KB1", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "12351658", "url": "https://pubmed.ncbi.nlm.nih.gov/12351658" }, { "database": "PubMed", "id": "12510059", "url": "https://pubmed.ncbi.nlm.nih.gov/12510059" }, { "database": "PubMed", "id": "14769130", "url": "https://pubmed.ncbi.nlm.nih.gov/14769130" }, { "database": "PubMed", "id": "15044323", "url": "https://pubmed.ncbi.nlm.nih.gov/15044323" }, { "database": "PubMed", "id": "15613682", "url": "https://pubmed.ncbi.nlm.nih.gov/15613682" }, { "database": "PubMed", "id": "15713122", "url": "https://pubmed.ncbi.nlm.nih.gov/15713122" }, { "database": "PubMed", "id": "15952059", "url": "https://pubmed.ncbi.nlm.nih.gov/15952059" }, { "database": "PubMed", "id": "16123357", "url": "https://pubmed.ncbi.nlm.nih.gov/16123357" }, { "database": "PubMed", "id": "16284649", "url": "https://pubmed.ncbi.nlm.nih.gov/16284649" }, { "database": "PubMed", "id": "16505239", "url": "https://pubmed.ncbi.nlm.nih.gov/16505239" }, { "database": "PubMed", "id": "16505244", "url": "https://pubmed.ncbi.nlm.nih.gov/16505244" }, { "database": "PubMed", "id": "16516141", "url": "https://pubmed.ncbi.nlm.nih.gov/16516141" }, { "database": "PubMed", "id": "16960890", "url": "https://pubmed.ncbi.nlm.nih.gov/16960890" }, { "database": "PubMed", "id": "17204522", "url": "https://pubmed.ncbi.nlm.nih.gov/17204522" }, { "database": "PubMed", "id": "17242212", "url": "https://pubmed.ncbi.nlm.nih.gov/17242212" }, { "database": "PubMed", "id": "17360977", "url": "https://pubmed.ncbi.nlm.nih.gov/17360977" }, { "database": "PubMed", "id": "17647275", "url": "https://pubmed.ncbi.nlm.nih.gov/17647275" }, { "database": "PubMed", "id": "18160431", "url": "https://pubmed.ncbi.nlm.nih.gov/18160431" }, { "database": "PubMed", "id": "19501568", "url": "https://pubmed.ncbi.nlm.nih.gov/19501568" }, { "database": "PubMed", "id": "19567513", "url": "https://pubmed.ncbi.nlm.nih.gov/19567513" }, { "database": "PubMed", "id": "19593406", "url": "https://pubmed.ncbi.nlm.nih.gov/19593406" }, { "database": "PubMed", "id": "20393162", "url": "https://pubmed.ncbi.nlm.nih.gov/20393162" }, { "database": "PubMed", "id": "20685959", "url": "https://pubmed.ncbi.nlm.nih.gov/20685959" }, { "database": "PubMed", "id": "20863384", "url": "https://pubmed.ncbi.nlm.nih.gov/20863384" }, { "database": "PubMed", "id": "21040800", "url": "https://pubmed.ncbi.nlm.nih.gov/21040800" }, { "database": "PubMed", "id": "21252690", "url": "https://pubmed.ncbi.nlm.nih.gov/21252690" }, { "database": "PubMed", "id": "21589939", "url": "https://pubmed.ncbi.nlm.nih.gov/21589939" }, { "database": "PubMed", "id": "21852229", "url": "https://pubmed.ncbi.nlm.nih.gov/21852229" }, { "database": "PubMed", "id": "21937042", "url": "https://pubmed.ncbi.nlm.nih.gov/21937042" }, { "database": "PubMed", "id": "22348058", "url": "https://pubmed.ncbi.nlm.nih.gov/22348058" }, { "database": "PubMed", "id": "22457223", "url": "https://pubmed.ncbi.nlm.nih.gov/22457223" }, { "database": "PubMed", "id": "22862962", "url": "https://pubmed.ncbi.nlm.nih.gov/22862962" }, { "database": "PubMed", "id": "25580119", "url": "https://pubmed.ncbi.nlm.nih.gov/25580119" }, { "database": "PubMed", "id": "27207509", "url": "https://pubmed.ncbi.nlm.nih.gov/27207509" }, { "database": "PubMed", "id": "27340831", "url": "https://pubmed.ncbi.nlm.nih.gov/27340831" }, { "database": "PubMed", "id": "32536688", "url": "https://pubmed.ncbi.nlm.nih.gov/32536688" }, { "database": "PubMed", "id": "33173197", "url": "https://pubmed.ncbi.nlm.nih.gov/33173197" }, { "database": "PubMed", "id": "35833836", "url": "https://pubmed.ncbi.nlm.nih.gov/35833836" }, { "database": "PubMed", "id": "18498745", "url": "https://pubmed.ncbi.nlm.nih.gov/18498745" } ], "site_lbl": "Ser312", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 616, "end_pos": 616, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "16354680", "url": "https://pubmed.ncbi.nlm.nih.gov/16354680" }, { "database": "PubMed", "id": "8626671", "url": "https://pubmed.ncbi.nlm.nih.gov/8626671" }, { "database": "PubMed", "id": "14769130", "url": "https://pubmed.ncbi.nlm.nih.gov/14769130" }, { "database": "PubMed", "id": "15044323", "url": "https://pubmed.ncbi.nlm.nih.gov/15044323" }, { "database": "PubMed", "id": "15713122", "url": "https://pubmed.ncbi.nlm.nih.gov/15713122" }, { "database": "PubMed", "id": "17242212", "url": "https://pubmed.ncbi.nlm.nih.gov/17242212" }, { "database": "PubMed", "id": "17360977", "url": "https://pubmed.ncbi.nlm.nih.gov/17360977" }, { "database": "PubMed", "id": "17640984", "url": "https://pubmed.ncbi.nlm.nih.gov/17640984" }, { "database": "PubMed", "id": "21937042", "url": "https://pubmed.ncbi.nlm.nih.gov/21937042" }, { "database": "PubMed", "id": "22476197", "url": "https://pubmed.ncbi.nlm.nih.gov/22476197" }, { "database": "PubMed", "id": "26297026", "url": "https://pubmed.ncbi.nlm.nih.gov/26297026" } ], "site_lbl": "Ser616", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 636, "end_pos": 636, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by RPS6KB1", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "16131083", "url": "https://pubmed.ncbi.nlm.nih.gov/16131083" }, { "database": "PubMed", "id": "19651622", "url": "https://pubmed.ncbi.nlm.nih.gov/19651622" }, { "database": "PubMed", "id": "16354680", "url": "https://pubmed.ncbi.nlm.nih.gov/16354680" }, { "database": "PubMed", "id": "11287630", "url": "https://pubmed.ncbi.nlm.nih.gov/11287630" }, { "database": "PubMed", "id": "12765939", "url": "https://pubmed.ncbi.nlm.nih.gov/12765939" }, { "database": "PubMed", "id": "14769130", "url": "https://pubmed.ncbi.nlm.nih.gov/14769130" }, { "database": "PubMed", "id": "15576463", "url": "https://pubmed.ncbi.nlm.nih.gov/15576463" }, { "database": "PubMed", "id": "16123357", "url": "https://pubmed.ncbi.nlm.nih.gov/16123357" }, { "database": "PubMed", "id": "16284649", "url": "https://pubmed.ncbi.nlm.nih.gov/16284649" }, { "database": "PubMed", "id": "17360977", "url": "https://pubmed.ncbi.nlm.nih.gov/17360977" }, { "database": "PubMed", "id": "17640984", "url": "https://pubmed.ncbi.nlm.nih.gov/17640984" }, { "database": "PubMed", "id": "18597775", "url": "https://pubmed.ncbi.nlm.nih.gov/18597775" }, { "database": "PubMed", "id": "18952604", "url": "https://pubmed.ncbi.nlm.nih.gov/18952604" }, { "database": "PubMed", "id": "19561084", "url": "https://pubmed.ncbi.nlm.nih.gov/19561084" }, { "database": "PubMed", "id": "19581421", "url": "https://pubmed.ncbi.nlm.nih.gov/19581421" }, { "database": "PubMed", "id": "20203102", "url": "https://pubmed.ncbi.nlm.nih.gov/20203102" }, { "database": "PubMed", "id": "21478152", "url": "https://pubmed.ncbi.nlm.nih.gov/21478152" }, { "database": "PubMed", "id": "21829658", "url": "https://pubmed.ncbi.nlm.nih.gov/21829658" }, { "database": "PubMed", "id": "22348058", "url": "https://pubmed.ncbi.nlm.nih.gov/22348058" }, { "database": "PubMed", "id": "22966072", "url": "https://pubmed.ncbi.nlm.nih.gov/22966072" }, { "database": "PubMed", "id": "23512499", "url": "https://pubmed.ncbi.nlm.nih.gov/23512499" }, { "database": "PubMed", "id": "25667991", "url": "https://pubmed.ncbi.nlm.nih.gov/25667991" }, { "database": "PubMed", "id": "25799226", "url": "https://pubmed.ncbi.nlm.nih.gov/25799226" }, { "database": "PubMed", "id": "25813876", "url": "https://pubmed.ncbi.nlm.nih.gov/25813876" }, { "database": "PubMed", "id": "26077338", "url": "https://pubmed.ncbi.nlm.nih.gov/26077338" }, { "database": "PubMed", "id": "27434075", "url": "https://pubmed.ncbi.nlm.nih.gov/27434075" }, { "database": "PubMed", "id": "28652303", "url": "https://pubmed.ncbi.nlm.nih.gov/28652303" }, { "database": "PubMed", "id": "28934129", "url": "https://pubmed.ncbi.nlm.nih.gov/28934129" }, { "database": "PubMed", "id": "30381640", "url": "https://pubmed.ncbi.nlm.nih.gov/30381640" }, { "database": "PubMed", "id": "36111162", "url": "https://pubmed.ncbi.nlm.nih.gov/36111162" }, { "database": "PubMed", "id": "18498745", "url": "https://pubmed.ncbi.nlm.nih.gov/18498745" }, { "database": "PubMed", "id": "17081983", "url": "https://pubmed.ncbi.nlm.nih.gov/17081983" } ], "site_lbl": "Ser636", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 639, "end_pos": 639, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "16354680", "url": "https://pubmed.ncbi.nlm.nih.gov/16354680" }, { "database": "PubMed", "id": "11287630", "url": "https://pubmed.ncbi.nlm.nih.gov/11287630" }, { "database": "PubMed", "id": "14769130", "url": "https://pubmed.ncbi.nlm.nih.gov/14769130" }, { "database": "PubMed", "id": "15576463", "url": "https://pubmed.ncbi.nlm.nih.gov/15576463" }, { "database": "PubMed", "id": "16123357", "url": "https://pubmed.ncbi.nlm.nih.gov/16123357" }, { "database": "PubMed", "id": "19561084", "url": "https://pubmed.ncbi.nlm.nih.gov/19561084" }, { "database": "PubMed", "id": "20203102", "url": "https://pubmed.ncbi.nlm.nih.gov/20203102" }, { "database": "PubMed", "id": "21478152", "url": "https://pubmed.ncbi.nlm.nih.gov/21478152" }, { "database": "PubMed", "id": "21829658", "url": "https://pubmed.ncbi.nlm.nih.gov/21829658" }, { "database": "PubMed", "id": "23512499", "url": "https://pubmed.ncbi.nlm.nih.gov/23512499" }, { "database": "PubMed", "id": "25667991", "url": "https://pubmed.ncbi.nlm.nih.gov/25667991" }, { "database": "PubMed", "id": "25799226", "url": "https://pubmed.ncbi.nlm.nih.gov/25799226" }, { "database": "PubMed", "id": "30381640", "url": "https://pubmed.ncbi.nlm.nih.gov/30381640" } ], "site_lbl": "Ser639", "uniprot_canonical_ac": "P35568-1" } ], "record_id": "pubmed.14769130", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 4 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Activation of the hexosamine pathway leads to phosphorylation of insulin receptor substrate-1 on Ser307 and Ser612 and impairs the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin insulin biosynthetic pathway in RIN pancreatic beta-cells.", "journal": "Endocrinology", "date": "2004", "authors": "Andreozzi F, D'Alessandris C, Federici M, Laratta E, Del Guerra S, Del Prato S, Marchetti P, Lauro R, Perticone F, Sesti G", "reference": { "type": "PubMed", "id": "15001544", "url": "https://pubmed.ncbi.nlm.nih.gov/15001544" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 616, "end_pos": 616, "kinase_uniprot_canonical_ac": "P27361-1", "kinase_gene_name": "MAPK3", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "9395471", "url": "https://pubmed.ncbi.nlm.nih.gov/9395471" }, { "database": "PubMed", "id": "15001544", "url": "https://pubmed.ncbi.nlm.nih.gov/15001544" } ], "site_lbl": "Ser616", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 616, "end_pos": 616, "kinase_uniprot_canonical_ac": "P28482-1", "kinase_gene_name": "MAPK1", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "16131083", "url": "https://pubmed.ncbi.nlm.nih.gov/16131083" }, { "database": "PubMed", "id": "9395471", "url": "https://pubmed.ncbi.nlm.nih.gov/9395471" }, { "database": "PubMed", "id": "15001544", "url": "https://pubmed.ncbi.nlm.nih.gov/15001544" } ], "site_lbl": "Ser616", "uniprot_canonical_ac": "P35568-1" } ], "record_id": "pubmed.15001544", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Mammalian target of rapamycin regulates IRS-1 serine 307 phosphorylation.", "journal": "Biochemical and biophysical research communications", "date": "2004", "authors": "Carlson CJ, White MF, Rondinone CM", "reference": { "type": "PubMed", "id": "15020250", "url": "https://pubmed.ncbi.nlm.nih.gov/15020250" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 307, "end_pos": 307, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by RPS6KB1", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "11160134", "url": "https://pubmed.ncbi.nlm.nih.gov/11160134" }, { "database": "PubMed", "id": "11606564", "url": "https://pubmed.ncbi.nlm.nih.gov/11606564" }, { "database": "PubMed", "id": "12409308", "url": "https://pubmed.ncbi.nlm.nih.gov/12409308" }, { "database": "PubMed", "id": "12714600", "url": "https://pubmed.ncbi.nlm.nih.gov/12714600" }, { "database": "PubMed", "id": "12730242", "url": "https://pubmed.ncbi.nlm.nih.gov/12730242" }, { "database": "PubMed", "id": "14556646", "url": "https://pubmed.ncbi.nlm.nih.gov/14556646" }, { "database": "PubMed", "id": "14583092", "url": "https://pubmed.ncbi.nlm.nih.gov/14583092" }, { "database": "PubMed", "id": "14641015", "url": "https://pubmed.ncbi.nlm.nih.gov/14641015" }, { "database": "PubMed", "id": "14697666", "url": "https://pubmed.ncbi.nlm.nih.gov/14697666" }, { "database": "PubMed", "id": "15020250", "url": "https://pubmed.ncbi.nlm.nih.gov/15020250" }, { "database": "PubMed", "id": "15153564", "url": "https://pubmed.ncbi.nlm.nih.gov/15153564" }, { "database": "PubMed", "id": "15582605", "url": "https://pubmed.ncbi.nlm.nih.gov/15582605" }, { "database": "PubMed", "id": "15802620", "url": "https://pubmed.ncbi.nlm.nih.gov/15802620" }, { "database": "PubMed", "id": "16046301", "url": "https://pubmed.ncbi.nlm.nih.gov/16046301" }, { "database": "PubMed", "id": "16055440", "url": "https://pubmed.ncbi.nlm.nih.gov/16055440" }, { "database": "PubMed", "id": "16099428", "url": "https://pubmed.ncbi.nlm.nih.gov/16099428" }, { "database": "PubMed", "id": "16210322", "url": "https://pubmed.ncbi.nlm.nih.gov/16210322" }, { "database": "PubMed", "id": "16269459", "url": "https://pubmed.ncbi.nlm.nih.gov/16269459" }, { "database": "PubMed", "id": "16516141", "url": "https://pubmed.ncbi.nlm.nih.gov/16516141" }, { "database": "PubMed", "id": "16754954", "url": "https://pubmed.ncbi.nlm.nih.gov/16754954" }, { "database": "PubMed", "id": "16839860", "url": "https://pubmed.ncbi.nlm.nih.gov/16839860" }, { "database": "PubMed", "id": "17077083", "url": "https://pubmed.ncbi.nlm.nih.gov/17077083" }, { "database": "PubMed", "id": "17095576", "url": "https://pubmed.ncbi.nlm.nih.gov/17095576" }, { "database": "PubMed", "id": "17276034", "url": "https://pubmed.ncbi.nlm.nih.gov/17276034" }, { "database": "PubMed", "id": "17481767", "url": "https://pubmed.ncbi.nlm.nih.gov/17481767" }, { "database": "PubMed", "id": "17575262", "url": "https://pubmed.ncbi.nlm.nih.gov/17575262" }, { "database": "PubMed", "id": "18187553", "url": "https://pubmed.ncbi.nlm.nih.gov/18187553" }, { "database": "PubMed", "id": "18372392", "url": "https://pubmed.ncbi.nlm.nih.gov/18372392" }, { "database": "PubMed", "id": "18380932", "url": "https://pubmed.ncbi.nlm.nih.gov/18380932" }, { "database": "PubMed", "id": "18496818", "url": "https://pubmed.ncbi.nlm.nih.gov/18496818" }, { "database": "PubMed", "id": "18952604", "url": "https://pubmed.ncbi.nlm.nih.gov/18952604" }, { "database": "PubMed", "id": "19095745", "url": "https://pubmed.ncbi.nlm.nih.gov/19095745" }, { "database": "PubMed", "id": "19524129", "url": "https://pubmed.ncbi.nlm.nih.gov/19524129" }, { "database": "PubMed", "id": "19897715", "url": "https://pubmed.ncbi.nlm.nih.gov/19897715" }, { "database": "PubMed", "id": "20351777", "url": "https://pubmed.ncbi.nlm.nih.gov/20351777" }, { "database": "PubMed", "id": "20382011", "url": "https://pubmed.ncbi.nlm.nih.gov/20382011" }, { "database": "PubMed", "id": "20384568", "url": "https://pubmed.ncbi.nlm.nih.gov/20384568" }, { "database": "PubMed", "id": "20541543", "url": "https://pubmed.ncbi.nlm.nih.gov/20541543" }, { "database": "PubMed", "id": "20587749", "url": "https://pubmed.ncbi.nlm.nih.gov/20587749" }, { "database": "PubMed", "id": "20594161", "url": "https://pubmed.ncbi.nlm.nih.gov/20594161" }, { "database": "PubMed", "id": "20594757", "url": "https://pubmed.ncbi.nlm.nih.gov/20594757" }, { "database": "PubMed", "id": "20702573", "url": "https://pubmed.ncbi.nlm.nih.gov/20702573" }, { "database": "PubMed", "id": "21119656", "url": "https://pubmed.ncbi.nlm.nih.gov/21119656" }, { "database": "PubMed", "id": "21478152", "url": "https://pubmed.ncbi.nlm.nih.gov/21478152" }, { "database": "PubMed", "id": "21505982", "url": "https://pubmed.ncbi.nlm.nih.gov/21505982" }, { "database": "PubMed", "id": "21786209", "url": "https://pubmed.ncbi.nlm.nih.gov/21786209" }, { "database": "PubMed", "id": "21852229", "url": "https://pubmed.ncbi.nlm.nih.gov/21852229" }, { "database": "PubMed", "id": "21900690", "url": "https://pubmed.ncbi.nlm.nih.gov/21900690" }, { "database": "PubMed", "id": "22046423", "url": "https://pubmed.ncbi.nlm.nih.gov/22046423" }, { "database": "PubMed", "id": "22227580", "url": "https://pubmed.ncbi.nlm.nih.gov/22227580" }, { "database": "PubMed", "id": "22266116", "url": "https://pubmed.ncbi.nlm.nih.gov/22266116" }, { "database": "PubMed", "id": "22328823", "url": "https://pubmed.ncbi.nlm.nih.gov/22328823" }, { "database": "PubMed", "id": "22348058", "url": "https://pubmed.ncbi.nlm.nih.gov/22348058" }, { "database": "PubMed", "id": "22491740", "url": "https://pubmed.ncbi.nlm.nih.gov/22491740" }, { "database": "PubMed", "id": "22728372", "url": "https://pubmed.ncbi.nlm.nih.gov/22728372" }, { "database": "PubMed", "id": "22766331", "url": "https://pubmed.ncbi.nlm.nih.gov/22766331" }, { "database": "PubMed", "id": "23095254", "url": "https://pubmed.ncbi.nlm.nih.gov/23095254" }, { "database": "PubMed", "id": "23174405", "url": "https://pubmed.ncbi.nlm.nih.gov/23174405" }, { "database": "PubMed", "id": "23182460", "url": "https://pubmed.ncbi.nlm.nih.gov/23182460" }, { "database": "PubMed", "id": "23481042", "url": "https://pubmed.ncbi.nlm.nih.gov/23481042" }, { "database": "PubMed", "id": "23566306", "url": "https://pubmed.ncbi.nlm.nih.gov/23566306" }, { "database": "PubMed", "id": "23592917", "url": "https://pubmed.ncbi.nlm.nih.gov/23592917" }, { "database": "PubMed", "id": "23891856", "url": "https://pubmed.ncbi.nlm.nih.gov/23891856" }, { "database": "PubMed", "id": "23958494", "url": "https://pubmed.ncbi.nlm.nih.gov/23958494" }, { "database": "PubMed", "id": "24068326", "url": "https://pubmed.ncbi.nlm.nih.gov/24068326" }, { "database": "PubMed", "id": "24846082", "url": "https://pubmed.ncbi.nlm.nih.gov/24846082" }, { "database": "PubMed", "id": "25120613", "url": "https://pubmed.ncbi.nlm.nih.gov/25120613" }, { "database": "PubMed", "id": "25355439", "url": "https://pubmed.ncbi.nlm.nih.gov/25355439" }, { "database": "PubMed", "id": "25645159", "url": "https://pubmed.ncbi.nlm.nih.gov/25645159" }, { "database": "PubMed", "id": "25799226", "url": "https://pubmed.ncbi.nlm.nih.gov/25799226" }, { "database": "PubMed", "id": "26604643", "url": "https://pubmed.ncbi.nlm.nih.gov/26604643" }, { "database": "PubMed", "id": "26698173", "url": "https://pubmed.ncbi.nlm.nih.gov/26698173" }, { "database": "PubMed", "id": "26704265", "url": "https://pubmed.ncbi.nlm.nih.gov/26704265" }, { "database": "PubMed", "id": "26899161", "url": "https://pubmed.ncbi.nlm.nih.gov/26899161" }, { "database": "PubMed", "id": "26983645", "url": "https://pubmed.ncbi.nlm.nih.gov/26983645" }, { "database": "PubMed", "id": "27222060", "url": "https://pubmed.ncbi.nlm.nih.gov/27222060" }, { "database": "PubMed", "id": "27506476", "url": "https://pubmed.ncbi.nlm.nih.gov/27506476" }, { "database": "PubMed", "id": "27544192", "url": "https://pubmed.ncbi.nlm.nih.gov/27544192" }, { "database": "PubMed", "id": "27686967", "url": "https://pubmed.ncbi.nlm.nih.gov/27686967" }, { "database": "PubMed", "id": "27936435", "url": "https://pubmed.ncbi.nlm.nih.gov/27936435" }, { "database": "PubMed", "id": "28161417", "url": "https://pubmed.ncbi.nlm.nih.gov/28161417" }, { "database": "PubMed", "id": "28656239", "url": "https://pubmed.ncbi.nlm.nih.gov/28656239" }, { "database": "PubMed", "id": "28731188", "url": "https://pubmed.ncbi.nlm.nih.gov/28731188" }, { "database": "PubMed", "id": "28790390", "url": "https://pubmed.ncbi.nlm.nih.gov/28790390" }, { "database": "PubMed", "id": "28934129", "url": "https://pubmed.ncbi.nlm.nih.gov/28934129" }, { "database": "PubMed", "id": "29177868", "url": "https://pubmed.ncbi.nlm.nih.gov/29177868" }, { "database": "PubMed", "id": "29311680", "url": "https://pubmed.ncbi.nlm.nih.gov/29311680" }, { "database": "PubMed", "id": "29393871", "url": "https://pubmed.ncbi.nlm.nih.gov/29393871" }, { "database": "PubMed", "id": "29432553", "url": "https://pubmed.ncbi.nlm.nih.gov/29432553" }, { "database": "PubMed", "id": "29698741", "url": "https://pubmed.ncbi.nlm.nih.gov/29698741" }, { "database": "PubMed", "id": "29738527", "url": "https://pubmed.ncbi.nlm.nih.gov/29738527" }, { "database": "PubMed", "id": "30240640", "url": "https://pubmed.ncbi.nlm.nih.gov/30240640" }, { "database": "PubMed", "id": "30374127", "url": "https://pubmed.ncbi.nlm.nih.gov/30374127" }, { "database": "PubMed", "id": "30572687", "url": "https://pubmed.ncbi.nlm.nih.gov/30572687" }, { "database": "PubMed", "id": "31137828", "url": "https://pubmed.ncbi.nlm.nih.gov/31137828" }, { "database": "PubMed", "id": "31311314", "url": "https://pubmed.ncbi.nlm.nih.gov/31311314" }, { "database": "PubMed", "id": "31396538", "url": "https://pubmed.ncbi.nlm.nih.gov/31396538" }, { "database": "PubMed", "id": "32875583", "url": "https://pubmed.ncbi.nlm.nih.gov/32875583" }, { "database": "PubMed", "id": "33723215", "url": "https://pubmed.ncbi.nlm.nih.gov/33723215" }, { "database": "PubMed", "id": "35656886", "url": "https://pubmed.ncbi.nlm.nih.gov/35656886" }, { "database": "PubMed", "id": "18498745", "url": "https://pubmed.ncbi.nlm.nih.gov/18498745" } ], "site_lbl": "Ser307", "uniprot_canonical_ac": "P35568-1" } ], "record_id": "pubmed.15020250", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Angiotensin II impairs the insulin signaling pathway promoting production of nitric oxide by inducing phosphorylation of insulin receptor substrate-1 on Ser312 and Ser616 in human umbilical vein endothelial cells.", "journal": "Circulation research", "date": "2004", "authors": "Andreozzi F, Laratta E, Sciacqua A, Perticone F, Sesti G", "reference": { "type": "PubMed", "id": "15044323", "url": "https://pubmed.ncbi.nlm.nih.gov/15044323" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 312, "end_pos": 312, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by IKKB, MAPK8 and RPS6KB1", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "12351658", "url": "https://pubmed.ncbi.nlm.nih.gov/12351658" }, { "database": "PubMed", "id": "12510059", "url": "https://pubmed.ncbi.nlm.nih.gov/12510059" }, { "database": "PubMed", "id": "14769130", "url": "https://pubmed.ncbi.nlm.nih.gov/14769130" }, { "database": "PubMed", "id": "15044323", "url": "https://pubmed.ncbi.nlm.nih.gov/15044323" }, { "database": "PubMed", "id": "15613682", "url": "https://pubmed.ncbi.nlm.nih.gov/15613682" }, { "database": "PubMed", "id": "15713122", "url": "https://pubmed.ncbi.nlm.nih.gov/15713122" }, { "database": "PubMed", "id": "15952059", "url": "https://pubmed.ncbi.nlm.nih.gov/15952059" }, { "database": "PubMed", "id": "16123357", "url": "https://pubmed.ncbi.nlm.nih.gov/16123357" }, { "database": "PubMed", "id": "16284649", "url": "https://pubmed.ncbi.nlm.nih.gov/16284649" }, { "database": "PubMed", "id": "16505239", "url": "https://pubmed.ncbi.nlm.nih.gov/16505239" }, { "database": "PubMed", "id": "16505244", "url": "https://pubmed.ncbi.nlm.nih.gov/16505244" }, { "database": "PubMed", "id": "16516141", "url": "https://pubmed.ncbi.nlm.nih.gov/16516141" }, { "database": "PubMed", "id": "16960890", "url": "https://pubmed.ncbi.nlm.nih.gov/16960890" }, { "database": "PubMed", "id": "17204522", "url": "https://pubmed.ncbi.nlm.nih.gov/17204522" }, { "database": "PubMed", "id": "17242212", "url": "https://pubmed.ncbi.nlm.nih.gov/17242212" }, { "database": "PubMed", "id": "17360977", "url": "https://pubmed.ncbi.nlm.nih.gov/17360977" }, { "database": "PubMed", "id": "17647275", "url": "https://pubmed.ncbi.nlm.nih.gov/17647275" }, { "database": "PubMed", "id": "18160431", "url": "https://pubmed.ncbi.nlm.nih.gov/18160431" }, { "database": "PubMed", "id": "19501568", "url": "https://pubmed.ncbi.nlm.nih.gov/19501568" }, { "database": "PubMed", "id": "19567513", "url": "https://pubmed.ncbi.nlm.nih.gov/19567513" }, { "database": "PubMed", "id": "19593406", "url": "https://pubmed.ncbi.nlm.nih.gov/19593406" }, { "database": "PubMed", "id": "20393162", "url": "https://pubmed.ncbi.nlm.nih.gov/20393162" }, { "database": "PubMed", "id": "20685959", "url": "https://pubmed.ncbi.nlm.nih.gov/20685959" }, { "database": "PubMed", "id": "20863384", "url": "https://pubmed.ncbi.nlm.nih.gov/20863384" }, { "database": "PubMed", "id": "21040800", "url": "https://pubmed.ncbi.nlm.nih.gov/21040800" }, { "database": "PubMed", "id": "21252690", "url": "https://pubmed.ncbi.nlm.nih.gov/21252690" }, { "database": "PubMed", "id": "21589939", "url": "https://pubmed.ncbi.nlm.nih.gov/21589939" }, { "database": "PubMed", "id": "21852229", "url": "https://pubmed.ncbi.nlm.nih.gov/21852229" }, { "database": "PubMed", "id": "21937042", "url": "https://pubmed.ncbi.nlm.nih.gov/21937042" }, { "database": "PubMed", "id": "22348058", "url": "https://pubmed.ncbi.nlm.nih.gov/22348058" }, { "database": "PubMed", "id": "22457223", "url": "https://pubmed.ncbi.nlm.nih.gov/22457223" }, { "database": "PubMed", "id": "22862962", "url": "https://pubmed.ncbi.nlm.nih.gov/22862962" }, { "database": "PubMed", "id": "25580119", "url": "https://pubmed.ncbi.nlm.nih.gov/25580119" }, { "database": "PubMed", "id": "27207509", "url": "https://pubmed.ncbi.nlm.nih.gov/27207509" }, { "database": "PubMed", "id": "27340831", "url": "https://pubmed.ncbi.nlm.nih.gov/27340831" }, { "database": "PubMed", "id": "32536688", "url": "https://pubmed.ncbi.nlm.nih.gov/32536688" }, { "database": "PubMed", "id": "33173197", "url": "https://pubmed.ncbi.nlm.nih.gov/33173197" }, { "database": "PubMed", "id": "35833836", "url": "https://pubmed.ncbi.nlm.nih.gov/35833836" }, { "database": "PubMed", "id": "18498745", "url": "https://pubmed.ncbi.nlm.nih.gov/18498745" } ], "site_lbl": "Ser312", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 612, "end_pos": 612, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by INSR", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "12220227", "url": "https://pubmed.ncbi.nlm.nih.gov/12220227" }, { "database": "IntAct", "id": "P35568", "url": "https://www.ebi.ac.uk/intact/interactors/id:P35568*" }, { "database": "PubMed", "id": "16230374", "url": "https://pubmed.ncbi.nlm.nih.gov/16230374" }, { "database": "PubMed", "id": "11416002", "url": "https://pubmed.ncbi.nlm.nih.gov/11416002" }, { "database": "PRO", "id": "P35568", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=P35568" }, { "database": "PubMed", "id": "15044323", "url": "https://pubmed.ncbi.nlm.nih.gov/15044323" }, { "database": "PubMed", "id": "16188907", "url": "https://pubmed.ncbi.nlm.nih.gov/16188907" }, { "database": "PubMed", "id": "17242212", "url": "https://pubmed.ncbi.nlm.nih.gov/17242212" }, { "database": "PubMed", "id": "17902048", "url": "https://pubmed.ncbi.nlm.nih.gov/17902048" }, { "database": "PubMed", "id": "19762915", "url": "https://pubmed.ncbi.nlm.nih.gov/19762915" }, { "database": "PubMed", "id": "20150288", "url": "https://pubmed.ncbi.nlm.nih.gov/20150288" }, { "database": "PubMed", "id": "21829658", "url": "https://pubmed.ncbi.nlm.nih.gov/21829658" }, { "database": "PubMed", "id": "21939528", "url": "https://pubmed.ncbi.nlm.nih.gov/21939528" }, { "database": "PubMed", "id": "23360399", "url": "https://pubmed.ncbi.nlm.nih.gov/23360399" }, { "database": "PubMed", "id": "23460259", "url": "https://pubmed.ncbi.nlm.nih.gov/23460259" }, { "database": "PubMed", "id": "23688189", "url": "https://pubmed.ncbi.nlm.nih.gov/23688189" }, { "database": "PubMed", "id": "25302072", "url": "https://pubmed.ncbi.nlm.nih.gov/25302072" }, { "database": "PubMed", "id": "25886138", "url": "https://pubmed.ncbi.nlm.nih.gov/25886138" }, { "database": "PubMed", "id": "26297026", "url": "https://pubmed.ncbi.nlm.nih.gov/26297026" }, { "database": "PubMed", "id": "26874193", "url": "https://pubmed.ncbi.nlm.nih.gov/26874193" }, { "database": "PubMed", "id": "28161417", "url": "https://pubmed.ncbi.nlm.nih.gov/28161417" }, { "database": "PubMed", "id": "28345670", "url": "https://pubmed.ncbi.nlm.nih.gov/28345670" }, { "database": "PubMed", "id": "28414818", "url": "https://pubmed.ncbi.nlm.nih.gov/28414818" }, { "database": "PubMed", "id": "28934129", "url": "https://pubmed.ncbi.nlm.nih.gov/28934129" }, { "database": "PubMed", "id": "28955049", "url": "https://pubmed.ncbi.nlm.nih.gov/28955049" }, { "database": "PubMed", "id": "29259227", "url": "https://pubmed.ncbi.nlm.nih.gov/29259227" }, { "database": "PubMed", "id": "29486856", "url": "https://pubmed.ncbi.nlm.nih.gov/29486856" }, { "database": "PubMed", "id": "30092354", "url": "https://pubmed.ncbi.nlm.nih.gov/30092354" }, { "database": "PubMed", "id": "23401856", "url": "https://pubmed.ncbi.nlm.nih.gov/23401856" } ], "site_lbl": "Tyr612", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 616, "end_pos": 616, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "16354680", "url": "https://pubmed.ncbi.nlm.nih.gov/16354680" }, { "database": "PubMed", "id": "8626671", "url": "https://pubmed.ncbi.nlm.nih.gov/8626671" }, { "database": "PubMed", "id": "14769130", "url": "https://pubmed.ncbi.nlm.nih.gov/14769130" }, { "database": "PubMed", "id": "15044323", "url": "https://pubmed.ncbi.nlm.nih.gov/15044323" }, { "database": "PubMed", "id": "15713122", "url": "https://pubmed.ncbi.nlm.nih.gov/15713122" }, { "database": "PubMed", "id": "17242212", "url": "https://pubmed.ncbi.nlm.nih.gov/17242212" }, { "database": "PubMed", "id": "17360977", "url": "https://pubmed.ncbi.nlm.nih.gov/17360977" }, { "database": "PubMed", "id": "17640984", "url": "https://pubmed.ncbi.nlm.nih.gov/17640984" }, { "database": "PubMed", "id": "21937042", "url": "https://pubmed.ncbi.nlm.nih.gov/21937042" }, { "database": "PubMed", "id": "22476197", "url": "https://pubmed.ncbi.nlm.nih.gov/22476197" }, { "database": "PubMed", "id": "26297026", "url": "https://pubmed.ncbi.nlm.nih.gov/26297026" } ], "site_lbl": "Ser616", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 632, "end_pos": 632, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by INSR", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "IntAct", "id": "P35568", "url": "https://www.ebi.ac.uk/intact/interactors/id:P35568*" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "11416002", "url": "https://pubmed.ncbi.nlm.nih.gov/11416002" }, { "database": "PubMed", "id": "7680095", "url": "https://pubmed.ncbi.nlm.nih.gov/7680095" }, { "database": "PubMed", "id": "7680644", "url": "https://pubmed.ncbi.nlm.nih.gov/7680644" }, { "database": "PubMed", "id": "8382612", "url": "https://pubmed.ncbi.nlm.nih.gov/8382612" }, { "database": "PubMed", "id": "15044323", "url": "https://pubmed.ncbi.nlm.nih.gov/15044323" }, { "database": "PubMed", "id": "17279354", "url": "https://pubmed.ncbi.nlm.nih.gov/17279354" }, { "database": "PubMed", "id": "17640984", "url": "https://pubmed.ncbi.nlm.nih.gov/17640984" }, { "database": "PubMed", "id": "22558377", "url": "https://pubmed.ncbi.nlm.nih.gov/22558377" }, { "database": "PubMed", "id": "23404947", "url": "https://pubmed.ncbi.nlm.nih.gov/23404947" }, { "database": "PubMed", "id": "26077338", "url": "https://pubmed.ncbi.nlm.nih.gov/26077338" }, { "database": "PubMed", "id": "28414818", "url": "https://pubmed.ncbi.nlm.nih.gov/28414818" }, { "database": "PubMed", "id": "28934129", "url": "https://pubmed.ncbi.nlm.nih.gov/28934129" }, { "database": "PubMed", "id": "29698741", "url": "https://pubmed.ncbi.nlm.nih.gov/29698741" }, { "database": "PubMed", "id": "30863203", "url": "https://pubmed.ncbi.nlm.nih.gov/30863203" }, { "database": "PubMed", "id": "31137828", "url": "https://pubmed.ncbi.nlm.nih.gov/31137828" }, { "database": "PubMed", "id": "31620609", "url": "https://pubmed.ncbi.nlm.nih.gov/31620609" }, { "database": "PubMed", "id": "23401856", "url": "https://pubmed.ncbi.nlm.nih.gov/23401856" } ], "site_lbl": "Tyr632", "uniprot_canonical_ac": "P35568-1" } ], "record_id": "pubmed.15044323", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 4 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Regulation of muscle protein degradation: coordinated control of apoptotic and ubiquitin-proteasome systems by phosphatidylinositol 3 kinase.", "journal": "Journal of the American Society of Nephrology : JASN", "date": "2004", "authors": "Lee SW, Dai G, Hu Z, Wang X, Du J, Mitch WE", "reference": { "type": "PubMed", "id": "15153564", "url": "https://pubmed.ncbi.nlm.nih.gov/15153564" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 307, "end_pos": 307, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by RPS6KB1", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "11160134", "url": "https://pubmed.ncbi.nlm.nih.gov/11160134" }, { "database": "PubMed", "id": "11606564", "url": "https://pubmed.ncbi.nlm.nih.gov/11606564" }, { "database": "PubMed", "id": "12409308", "url": "https://pubmed.ncbi.nlm.nih.gov/12409308" }, { "database": "PubMed", "id": "12714600", "url": "https://pubmed.ncbi.nlm.nih.gov/12714600" }, { "database": "PubMed", "id": "12730242", "url": "https://pubmed.ncbi.nlm.nih.gov/12730242" }, { "database": "PubMed", "id": "14556646", "url": "https://pubmed.ncbi.nlm.nih.gov/14556646" }, { "database": "PubMed", "id": "14583092", "url": "https://pubmed.ncbi.nlm.nih.gov/14583092" }, { "database": "PubMed", "id": "14641015", "url": "https://pubmed.ncbi.nlm.nih.gov/14641015" }, { "database": "PubMed", "id": "14697666", "url": "https://pubmed.ncbi.nlm.nih.gov/14697666" }, { "database": "PubMed", "id": "15020250", "url": "https://pubmed.ncbi.nlm.nih.gov/15020250" }, { "database": "PubMed", "id": "15153564", "url": "https://pubmed.ncbi.nlm.nih.gov/15153564" }, { "database": "PubMed", "id": "15582605", "url": "https://pubmed.ncbi.nlm.nih.gov/15582605" }, { "database": "PubMed", "id": "15802620", "url": "https://pubmed.ncbi.nlm.nih.gov/15802620" }, { "database": "PubMed", "id": "16046301", "url": "https://pubmed.ncbi.nlm.nih.gov/16046301" }, { "database": "PubMed", "id": "16055440", "url": "https://pubmed.ncbi.nlm.nih.gov/16055440" }, { "database": "PubMed", "id": "16099428", "url": "https://pubmed.ncbi.nlm.nih.gov/16099428" }, { "database": "PubMed", "id": "16210322", "url": "https://pubmed.ncbi.nlm.nih.gov/16210322" }, { "database": "PubMed", "id": "16269459", "url": "https://pubmed.ncbi.nlm.nih.gov/16269459" }, { "database": "PubMed", "id": "16516141", "url": "https://pubmed.ncbi.nlm.nih.gov/16516141" }, { "database": "PubMed", "id": "16754954", "url": "https://pubmed.ncbi.nlm.nih.gov/16754954" }, { "database": "PubMed", "id": "16839860", "url": "https://pubmed.ncbi.nlm.nih.gov/16839860" }, { "database": "PubMed", "id": "17077083", "url": "https://pubmed.ncbi.nlm.nih.gov/17077083" }, { "database": "PubMed", "id": "17095576", "url": "https://pubmed.ncbi.nlm.nih.gov/17095576" }, { "database": "PubMed", "id": "17276034", "url": "https://pubmed.ncbi.nlm.nih.gov/17276034" }, { "database": "PubMed", "id": "17481767", "url": "https://pubmed.ncbi.nlm.nih.gov/17481767" }, { "database": "PubMed", "id": "17575262", "url": "https://pubmed.ncbi.nlm.nih.gov/17575262" }, { "database": "PubMed", "id": "18187553", "url": "https://pubmed.ncbi.nlm.nih.gov/18187553" }, { "database": "PubMed", "id": "18372392", "url": "https://pubmed.ncbi.nlm.nih.gov/18372392" }, { "database": "PubMed", "id": "18380932", "url": "https://pubmed.ncbi.nlm.nih.gov/18380932" }, { "database": "PubMed", "id": "18496818", "url": "https://pubmed.ncbi.nlm.nih.gov/18496818" }, { "database": "PubMed", "id": "18952604", "url": "https://pubmed.ncbi.nlm.nih.gov/18952604" }, { "database": "PubMed", "id": "19095745", "url": "https://pubmed.ncbi.nlm.nih.gov/19095745" }, { "database": "PubMed", "id": "19524129", "url": "https://pubmed.ncbi.nlm.nih.gov/19524129" }, { "database": "PubMed", "id": "19897715", "url": "https://pubmed.ncbi.nlm.nih.gov/19897715" }, { "database": "PubMed", "id": "20351777", "url": "https://pubmed.ncbi.nlm.nih.gov/20351777" }, { "database": "PubMed", "id": "20382011", "url": "https://pubmed.ncbi.nlm.nih.gov/20382011" }, { "database": "PubMed", "id": "20384568", "url": "https://pubmed.ncbi.nlm.nih.gov/20384568" }, { "database": "PubMed", "id": "20541543", "url": "https://pubmed.ncbi.nlm.nih.gov/20541543" }, { "database": "PubMed", "id": "20587749", "url": "https://pubmed.ncbi.nlm.nih.gov/20587749" }, { "database": "PubMed", "id": "20594161", "url": "https://pubmed.ncbi.nlm.nih.gov/20594161" }, { "database": "PubMed", "id": "20594757", "url": "https://pubmed.ncbi.nlm.nih.gov/20594757" }, { "database": "PubMed", "id": "20702573", "url": "https://pubmed.ncbi.nlm.nih.gov/20702573" }, { "database": "PubMed", "id": "21119656", "url": "https://pubmed.ncbi.nlm.nih.gov/21119656" }, { "database": "PubMed", "id": "21478152", "url": "https://pubmed.ncbi.nlm.nih.gov/21478152" }, { "database": "PubMed", "id": "21505982", "url": "https://pubmed.ncbi.nlm.nih.gov/21505982" }, { "database": "PubMed", "id": "21786209", "url": "https://pubmed.ncbi.nlm.nih.gov/21786209" }, { "database": "PubMed", "id": "21852229", "url": "https://pubmed.ncbi.nlm.nih.gov/21852229" }, { "database": "PubMed", "id": "21900690", "url": "https://pubmed.ncbi.nlm.nih.gov/21900690" }, { "database": "PubMed", "id": "22046423", "url": "https://pubmed.ncbi.nlm.nih.gov/22046423" }, { "database": "PubMed", "id": "22227580", "url": "https://pubmed.ncbi.nlm.nih.gov/22227580" }, { "database": "PubMed", "id": "22266116", "url": "https://pubmed.ncbi.nlm.nih.gov/22266116" }, { "database": "PubMed", "id": "22328823", "url": "https://pubmed.ncbi.nlm.nih.gov/22328823" }, { "database": "PubMed", "id": "22348058", "url": "https://pubmed.ncbi.nlm.nih.gov/22348058" }, { "database": "PubMed", "id": "22491740", "url": "https://pubmed.ncbi.nlm.nih.gov/22491740" }, { "database": "PubMed", "id": "22728372", "url": "https://pubmed.ncbi.nlm.nih.gov/22728372" }, { "database": "PubMed", "id": "22766331", "url": "https://pubmed.ncbi.nlm.nih.gov/22766331" }, { "database": "PubMed", "id": "23095254", "url": "https://pubmed.ncbi.nlm.nih.gov/23095254" }, { "database": "PubMed", "id": "23174405", "url": "https://pubmed.ncbi.nlm.nih.gov/23174405" }, { "database": "PubMed", "id": "23182460", "url": "https://pubmed.ncbi.nlm.nih.gov/23182460" }, { "database": "PubMed", "id": "23481042", "url": "https://pubmed.ncbi.nlm.nih.gov/23481042" }, { "database": "PubMed", "id": "23566306", "url": "https://pubmed.ncbi.nlm.nih.gov/23566306" }, { "database": "PubMed", "id": "23592917", "url": "https://pubmed.ncbi.nlm.nih.gov/23592917" }, { "database": "PubMed", "id": "23891856", "url": "https://pubmed.ncbi.nlm.nih.gov/23891856" }, { "database": "PubMed", "id": "23958494", "url": "https://pubmed.ncbi.nlm.nih.gov/23958494" }, { "database": "PubMed", "id": "24068326", "url": "https://pubmed.ncbi.nlm.nih.gov/24068326" }, { "database": "PubMed", "id": "24846082", "url": "https://pubmed.ncbi.nlm.nih.gov/24846082" }, { "database": "PubMed", "id": "25120613", "url": "https://pubmed.ncbi.nlm.nih.gov/25120613" }, { "database": "PubMed", "id": "25355439", "url": "https://pubmed.ncbi.nlm.nih.gov/25355439" }, { "database": "PubMed", "id": "25645159", "url": "https://pubmed.ncbi.nlm.nih.gov/25645159" }, { "database": "PubMed", "id": "25799226", "url": "https://pubmed.ncbi.nlm.nih.gov/25799226" }, { "database": "PubMed", "id": "26604643", "url": "https://pubmed.ncbi.nlm.nih.gov/26604643" }, { "database": "PubMed", "id": "26698173", "url": "https://pubmed.ncbi.nlm.nih.gov/26698173" }, { "database": "PubMed", "id": "26704265", "url": "https://pubmed.ncbi.nlm.nih.gov/26704265" }, { "database": "PubMed", "id": "26899161", "url": "https://pubmed.ncbi.nlm.nih.gov/26899161" }, { "database": "PubMed", "id": "26983645", "url": "https://pubmed.ncbi.nlm.nih.gov/26983645" }, { "database": "PubMed", "id": "27222060", "url": "https://pubmed.ncbi.nlm.nih.gov/27222060" }, { "database": "PubMed", "id": "27506476", "url": "https://pubmed.ncbi.nlm.nih.gov/27506476" }, { "database": "PubMed", "id": "27544192", "url": "https://pubmed.ncbi.nlm.nih.gov/27544192" }, { "database": "PubMed", "id": "27686967", "url": "https://pubmed.ncbi.nlm.nih.gov/27686967" }, { "database": "PubMed", "id": "27936435", "url": "https://pubmed.ncbi.nlm.nih.gov/27936435" }, { "database": "PubMed", "id": "28161417", "url": "https://pubmed.ncbi.nlm.nih.gov/28161417" }, { "database": "PubMed", "id": "28656239", "url": "https://pubmed.ncbi.nlm.nih.gov/28656239" }, { "database": "PubMed", "id": "28731188", "url": "https://pubmed.ncbi.nlm.nih.gov/28731188" }, { "database": "PubMed", "id": "28790390", "url": "https://pubmed.ncbi.nlm.nih.gov/28790390" }, { "database": "PubMed", "id": "28934129", "url": "https://pubmed.ncbi.nlm.nih.gov/28934129" }, { "database": "PubMed", "id": "29177868", "url": "https://pubmed.ncbi.nlm.nih.gov/29177868" }, { "database": "PubMed", "id": "29311680", "url": "https://pubmed.ncbi.nlm.nih.gov/29311680" }, { "database": "PubMed", "id": "29393871", "url": "https://pubmed.ncbi.nlm.nih.gov/29393871" }, { "database": "PubMed", "id": "29432553", "url": "https://pubmed.ncbi.nlm.nih.gov/29432553" }, { "database": "PubMed", "id": "29698741", "url": "https://pubmed.ncbi.nlm.nih.gov/29698741" }, { "database": "PubMed", "id": "29738527", "url": "https://pubmed.ncbi.nlm.nih.gov/29738527" }, { "database": "PubMed", "id": "30240640", "url": "https://pubmed.ncbi.nlm.nih.gov/30240640" }, { "database": "PubMed", "id": "30374127", "url": "https://pubmed.ncbi.nlm.nih.gov/30374127" }, { "database": "PubMed", "id": "30572687", "url": "https://pubmed.ncbi.nlm.nih.gov/30572687" }, { "database": "PubMed", "id": "31137828", "url": "https://pubmed.ncbi.nlm.nih.gov/31137828" }, { "database": "PubMed", "id": "31311314", "url": "https://pubmed.ncbi.nlm.nih.gov/31311314" }, { "database": "PubMed", "id": "31396538", "url": "https://pubmed.ncbi.nlm.nih.gov/31396538" }, { "database": "PubMed", "id": "32875583", "url": "https://pubmed.ncbi.nlm.nih.gov/32875583" }, { "database": "PubMed", "id": "33723215", "url": "https://pubmed.ncbi.nlm.nih.gov/33723215" }, { "database": "PubMed", "id": "35656886", "url": "https://pubmed.ncbi.nlm.nih.gov/35656886" }, { "database": "PubMed", "id": "18498745", "url": "https://pubmed.ncbi.nlm.nih.gov/18498745" } ], "site_lbl": "Ser307", "uniprot_canonical_ac": "P35568-1" } ], "record_id": "pubmed.15153564", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Activation of the mammalian target of rapamycin pathway acutely inhibits insulin signaling to Akt and glucose transport in 3T3-L1 and human adipocytes.", "journal": "Endocrinology", "date": "2005", "authors": "Tremblay F, Gagnon A, Veilleux A, Sorisky A, Marette A", "reference": { "type": "PubMed", "id": "15576463", "url": "https://pubmed.ncbi.nlm.nih.gov/15576463" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 636, "end_pos": 636, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by RPS6KB1", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "16131083", "url": "https://pubmed.ncbi.nlm.nih.gov/16131083" }, { "database": "PubMed", "id": "19651622", "url": "https://pubmed.ncbi.nlm.nih.gov/19651622" }, { "database": "PubMed", "id": "16354680", "url": "https://pubmed.ncbi.nlm.nih.gov/16354680" }, { "database": "PubMed", "id": "11287630", "url": "https://pubmed.ncbi.nlm.nih.gov/11287630" }, { "database": "PubMed", "id": "12765939", "url": "https://pubmed.ncbi.nlm.nih.gov/12765939" }, { "database": "PubMed", "id": "14769130", "url": "https://pubmed.ncbi.nlm.nih.gov/14769130" }, { "database": "PubMed", "id": "15576463", "url": "https://pubmed.ncbi.nlm.nih.gov/15576463" }, { "database": "PubMed", "id": "16123357", "url": "https://pubmed.ncbi.nlm.nih.gov/16123357" }, { "database": "PubMed", "id": "16284649", "url": "https://pubmed.ncbi.nlm.nih.gov/16284649" }, { "database": "PubMed", "id": "17360977", "url": "https://pubmed.ncbi.nlm.nih.gov/17360977" }, { "database": "PubMed", "id": "17640984", "url": "https://pubmed.ncbi.nlm.nih.gov/17640984" }, { "database": "PubMed", "id": "18597775", "url": "https://pubmed.ncbi.nlm.nih.gov/18597775" }, { "database": "PubMed", "id": "18952604", "url": "https://pubmed.ncbi.nlm.nih.gov/18952604" }, { "database": "PubMed", "id": "19561084", "url": "https://pubmed.ncbi.nlm.nih.gov/19561084" }, { "database": "PubMed", "id": "19581421", "url": "https://pubmed.ncbi.nlm.nih.gov/19581421" }, { "database": "PubMed", "id": "20203102", "url": "https://pubmed.ncbi.nlm.nih.gov/20203102" }, { "database": "PubMed", "id": "21478152", "url": "https://pubmed.ncbi.nlm.nih.gov/21478152" }, { "database": "PubMed", "id": "21829658", "url": "https://pubmed.ncbi.nlm.nih.gov/21829658" }, { "database": "PubMed", "id": "22348058", "url": "https://pubmed.ncbi.nlm.nih.gov/22348058" }, { "database": "PubMed", "id": "22966072", "url": "https://pubmed.ncbi.nlm.nih.gov/22966072" }, { "database": "PubMed", "id": "23512499", "url": "https://pubmed.ncbi.nlm.nih.gov/23512499" }, { "database": "PubMed", "id": "25667991", "url": "https://pubmed.ncbi.nlm.nih.gov/25667991" }, { "database": "PubMed", "id": "25799226", "url": "https://pubmed.ncbi.nlm.nih.gov/25799226" }, { "database": "PubMed", "id": "25813876", "url": "https://pubmed.ncbi.nlm.nih.gov/25813876" }, { "database": "PubMed", "id": "26077338", "url": "https://pubmed.ncbi.nlm.nih.gov/26077338" }, { "database": "PubMed", "id": "27434075", "url": "https://pubmed.ncbi.nlm.nih.gov/27434075" }, { "database": "PubMed", "id": "28652303", "url": "https://pubmed.ncbi.nlm.nih.gov/28652303" }, { "database": "PubMed", "id": "28934129", "url": "https://pubmed.ncbi.nlm.nih.gov/28934129" }, { "database": "PubMed", "id": "30381640", "url": "https://pubmed.ncbi.nlm.nih.gov/30381640" }, { "database": "PubMed", "id": "36111162", "url": "https://pubmed.ncbi.nlm.nih.gov/36111162" }, { "database": "PubMed", "id": "18498745", "url": "https://pubmed.ncbi.nlm.nih.gov/18498745" }, { "database": "PubMed", "id": "17081983", "url": "https://pubmed.ncbi.nlm.nih.gov/17081983" } ], "site_lbl": "Ser636", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 639, "end_pos": 639, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "16354680", "url": "https://pubmed.ncbi.nlm.nih.gov/16354680" }, { "database": "PubMed", "id": "11287630", "url": "https://pubmed.ncbi.nlm.nih.gov/11287630" }, { "database": "PubMed", "id": "14769130", "url": "https://pubmed.ncbi.nlm.nih.gov/14769130" }, { "database": "PubMed", "id": "15576463", "url": "https://pubmed.ncbi.nlm.nih.gov/15576463" }, { "database": "PubMed", "id": "16123357", "url": "https://pubmed.ncbi.nlm.nih.gov/16123357" }, { "database": "PubMed", "id": "19561084", "url": "https://pubmed.ncbi.nlm.nih.gov/19561084" }, { "database": "PubMed", "id": "20203102", "url": "https://pubmed.ncbi.nlm.nih.gov/20203102" }, { "database": "PubMed", "id": "21478152", "url": "https://pubmed.ncbi.nlm.nih.gov/21478152" }, { "database": "PubMed", "id": "21829658", "url": "https://pubmed.ncbi.nlm.nih.gov/21829658" }, { "database": "PubMed", "id": "23512499", "url": "https://pubmed.ncbi.nlm.nih.gov/23512499" }, { "database": "PubMed", "id": "25667991", "url": "https://pubmed.ncbi.nlm.nih.gov/25667991" }, { "database": "PubMed", "id": "25799226", "url": "https://pubmed.ncbi.nlm.nih.gov/25799226" }, { "database": "PubMed", "id": "30381640", "url": "https://pubmed.ncbi.nlm.nih.gov/30381640" } ], "site_lbl": "Ser639", "uniprot_canonical_ac": "P35568-1" } ], "record_id": "pubmed.15576463", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Negative regulation of adipogenesis from human mesenchymal stem cells by Jun N-terminal kinase.", "journal": "Biochemical and biophysical research communications", "date": "2005", "authors": "Tominaga S, Yamaguchi T, Takahashi S, Hirose F, Osumi T", "reference": { "type": "PubMed", "id": "15582605", "url": "https://pubmed.ncbi.nlm.nih.gov/15582605" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 307, "end_pos": 307, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by RPS6KB1", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "11160134", "url": "https://pubmed.ncbi.nlm.nih.gov/11160134" }, { "database": "PubMed", "id": "11606564", "url": "https://pubmed.ncbi.nlm.nih.gov/11606564" }, { "database": "PubMed", "id": "12409308", "url": "https://pubmed.ncbi.nlm.nih.gov/12409308" }, { "database": "PubMed", "id": "12714600", "url": "https://pubmed.ncbi.nlm.nih.gov/12714600" }, { "database": "PubMed", "id": "12730242", "url": "https://pubmed.ncbi.nlm.nih.gov/12730242" }, { "database": "PubMed", "id": "14556646", "url": "https://pubmed.ncbi.nlm.nih.gov/14556646" }, { "database": "PubMed", "id": "14583092", "url": "https://pubmed.ncbi.nlm.nih.gov/14583092" }, { "database": "PubMed", "id": "14641015", "url": "https://pubmed.ncbi.nlm.nih.gov/14641015" }, { "database": "PubMed", "id": "14697666", "url": "https://pubmed.ncbi.nlm.nih.gov/14697666" }, { "database": "PubMed", "id": "15020250", "url": "https://pubmed.ncbi.nlm.nih.gov/15020250" }, { "database": "PubMed", "id": "15153564", "url": "https://pubmed.ncbi.nlm.nih.gov/15153564" }, { "database": "PubMed", "id": "15582605", "url": "https://pubmed.ncbi.nlm.nih.gov/15582605" }, { "database": "PubMed", "id": "15802620", "url": "https://pubmed.ncbi.nlm.nih.gov/15802620" }, { "database": "PubMed", "id": "16046301", "url": "https://pubmed.ncbi.nlm.nih.gov/16046301" }, { "database": "PubMed", "id": "16055440", "url": "https://pubmed.ncbi.nlm.nih.gov/16055440" }, { "database": "PubMed", "id": "16099428", "url": "https://pubmed.ncbi.nlm.nih.gov/16099428" }, { "database": "PubMed", "id": "16210322", "url": "https://pubmed.ncbi.nlm.nih.gov/16210322" }, { "database": "PubMed", "id": "16269459", "url": "https://pubmed.ncbi.nlm.nih.gov/16269459" }, { "database": "PubMed", "id": "16516141", "url": "https://pubmed.ncbi.nlm.nih.gov/16516141" }, { "database": "PubMed", "id": "16754954", "url": "https://pubmed.ncbi.nlm.nih.gov/16754954" }, { "database": "PubMed", "id": "16839860", "url": "https://pubmed.ncbi.nlm.nih.gov/16839860" }, { "database": "PubMed", "id": "17077083", "url": "https://pubmed.ncbi.nlm.nih.gov/17077083" }, { "database": "PubMed", "id": "17095576", "url": "https://pubmed.ncbi.nlm.nih.gov/17095576" }, { "database": "PubMed", "id": "17276034", "url": "https://pubmed.ncbi.nlm.nih.gov/17276034" }, { "database": "PubMed", "id": "17481767", "url": "https://pubmed.ncbi.nlm.nih.gov/17481767" }, { "database": "PubMed", "id": "17575262", "url": "https://pubmed.ncbi.nlm.nih.gov/17575262" }, { "database": "PubMed", "id": "18187553", "url": "https://pubmed.ncbi.nlm.nih.gov/18187553" }, { "database": "PubMed", "id": "18372392", "url": "https://pubmed.ncbi.nlm.nih.gov/18372392" }, { "database": "PubMed", "id": "18380932", "url": "https://pubmed.ncbi.nlm.nih.gov/18380932" }, { "database": "PubMed", "id": "18496818", "url": "https://pubmed.ncbi.nlm.nih.gov/18496818" }, { "database": "PubMed", "id": "18952604", "url": "https://pubmed.ncbi.nlm.nih.gov/18952604" }, { "database": "PubMed", "id": "19095745", "url": "https://pubmed.ncbi.nlm.nih.gov/19095745" }, { "database": "PubMed", "id": "19524129", "url": "https://pubmed.ncbi.nlm.nih.gov/19524129" }, { "database": "PubMed", "id": "19897715", "url": "https://pubmed.ncbi.nlm.nih.gov/19897715" }, { "database": "PubMed", "id": "20351777", "url": "https://pubmed.ncbi.nlm.nih.gov/20351777" }, { "database": "PubMed", "id": "20382011", "url": "https://pubmed.ncbi.nlm.nih.gov/20382011" }, { "database": "PubMed", "id": "20384568", "url": "https://pubmed.ncbi.nlm.nih.gov/20384568" }, { "database": "PubMed", "id": "20541543", "url": "https://pubmed.ncbi.nlm.nih.gov/20541543" }, { "database": "PubMed", "id": "20587749", "url": "https://pubmed.ncbi.nlm.nih.gov/20587749" }, { "database": "PubMed", "id": "20594161", "url": "https://pubmed.ncbi.nlm.nih.gov/20594161" }, { "database": "PubMed", "id": "20594757", "url": "https://pubmed.ncbi.nlm.nih.gov/20594757" }, { "database": "PubMed", "id": "20702573", "url": "https://pubmed.ncbi.nlm.nih.gov/20702573" }, { "database": "PubMed", "id": "21119656", "url": "https://pubmed.ncbi.nlm.nih.gov/21119656" }, { "database": "PubMed", "id": "21478152", "url": "https://pubmed.ncbi.nlm.nih.gov/21478152" }, { "database": "PubMed", "id": "21505982", "url": "https://pubmed.ncbi.nlm.nih.gov/21505982" }, { "database": "PubMed", "id": "21786209", "url": "https://pubmed.ncbi.nlm.nih.gov/21786209" }, { "database": "PubMed", "id": "21852229", "url": "https://pubmed.ncbi.nlm.nih.gov/21852229" }, { "database": "PubMed", "id": "21900690", "url": "https://pubmed.ncbi.nlm.nih.gov/21900690" }, { "database": "PubMed", "id": "22046423", "url": "https://pubmed.ncbi.nlm.nih.gov/22046423" }, { "database": "PubMed", "id": "22227580", "url": "https://pubmed.ncbi.nlm.nih.gov/22227580" }, { "database": "PubMed", "id": "22266116", "url": "https://pubmed.ncbi.nlm.nih.gov/22266116" }, { "database": "PubMed", "id": "22328823", "url": "https://pubmed.ncbi.nlm.nih.gov/22328823" }, { "database": "PubMed", "id": "22348058", "url": "https://pubmed.ncbi.nlm.nih.gov/22348058" }, { "database": "PubMed", "id": "22491740", "url": "https://pubmed.ncbi.nlm.nih.gov/22491740" }, { "database": "PubMed", "id": "22728372", "url": "https://pubmed.ncbi.nlm.nih.gov/22728372" }, { "database": "PubMed", "id": "22766331", "url": "https://pubmed.ncbi.nlm.nih.gov/22766331" }, { "database": "PubMed", "id": "23095254", "url": "https://pubmed.ncbi.nlm.nih.gov/23095254" }, { "database": "PubMed", "id": "23174405", "url": "https://pubmed.ncbi.nlm.nih.gov/23174405" }, { "database": "PubMed", "id": "23182460", "url": "https://pubmed.ncbi.nlm.nih.gov/23182460" }, { "database": "PubMed", "id": "23481042", "url": "https://pubmed.ncbi.nlm.nih.gov/23481042" }, { "database": "PubMed", "id": "23566306", "url": "https://pubmed.ncbi.nlm.nih.gov/23566306" }, { "database": "PubMed", "id": "23592917", "url": "https://pubmed.ncbi.nlm.nih.gov/23592917" }, { "database": "PubMed", "id": "23891856", "url": "https://pubmed.ncbi.nlm.nih.gov/23891856" }, { "database": "PubMed", "id": "23958494", "url": "https://pubmed.ncbi.nlm.nih.gov/23958494" }, { "database": "PubMed", "id": "24068326", "url": "https://pubmed.ncbi.nlm.nih.gov/24068326" }, { "database": "PubMed", "id": "24846082", "url": "https://pubmed.ncbi.nlm.nih.gov/24846082" }, { "database": "PubMed", "id": "25120613", "url": "https://pubmed.ncbi.nlm.nih.gov/25120613" }, { "database": "PubMed", "id": "25355439", "url": "https://pubmed.ncbi.nlm.nih.gov/25355439" }, { "database": "PubMed", "id": "25645159", "url": "https://pubmed.ncbi.nlm.nih.gov/25645159" }, { "database": "PubMed", "id": "25799226", "url": "https://pubmed.ncbi.nlm.nih.gov/25799226" }, { "database": "PubMed", "id": "26604643", "url": "https://pubmed.ncbi.nlm.nih.gov/26604643" }, { "database": "PubMed", "id": "26698173", "url": "https://pubmed.ncbi.nlm.nih.gov/26698173" }, { "database": "PubMed", "id": "26704265", "url": "https://pubmed.ncbi.nlm.nih.gov/26704265" }, { "database": "PubMed", "id": "26899161", "url": "https://pubmed.ncbi.nlm.nih.gov/26899161" }, { "database": "PubMed", "id": "26983645", "url": "https://pubmed.ncbi.nlm.nih.gov/26983645" }, { "database": "PubMed", "id": "27222060", "url": "https://pubmed.ncbi.nlm.nih.gov/27222060" }, { "database": "PubMed", "id": "27506476", "url": "https://pubmed.ncbi.nlm.nih.gov/27506476" }, { "database": "PubMed", "id": "27544192", "url": "https://pubmed.ncbi.nlm.nih.gov/27544192" }, { "database": "PubMed", "id": "27686967", "url": "https://pubmed.ncbi.nlm.nih.gov/27686967" }, { "database": "PubMed", "id": "27936435", "url": "https://pubmed.ncbi.nlm.nih.gov/27936435" }, { "database": "PubMed", "id": "28161417", "url": "https://pubmed.ncbi.nlm.nih.gov/28161417" }, { "database": "PubMed", "id": "28656239", "url": "https://pubmed.ncbi.nlm.nih.gov/28656239" }, { "database": "PubMed", "id": "28731188", "url": "https://pubmed.ncbi.nlm.nih.gov/28731188" }, { "database": "PubMed", "id": "28790390", "url": "https://pubmed.ncbi.nlm.nih.gov/28790390" }, { "database": "PubMed", "id": "28934129", "url": "https://pubmed.ncbi.nlm.nih.gov/28934129" }, { "database": "PubMed", "id": "29177868", "url": "https://pubmed.ncbi.nlm.nih.gov/29177868" }, { "database": "PubMed", "id": "29311680", "url": "https://pubmed.ncbi.nlm.nih.gov/29311680" }, { "database": "PubMed", "id": "29393871", "url": "https://pubmed.ncbi.nlm.nih.gov/29393871" }, { "database": "PubMed", "id": "29432553", "url": "https://pubmed.ncbi.nlm.nih.gov/29432553" }, { "database": "PubMed", "id": "29698741", "url": "https://pubmed.ncbi.nlm.nih.gov/29698741" }, { "database": "PubMed", "id": "29738527", "url": "https://pubmed.ncbi.nlm.nih.gov/29738527" }, { "database": "PubMed", "id": "30240640", "url": "https://pubmed.ncbi.nlm.nih.gov/30240640" }, { "database": "PubMed", "id": "30374127", "url": "https://pubmed.ncbi.nlm.nih.gov/30374127" }, { "database": "PubMed", "id": "30572687", "url": "https://pubmed.ncbi.nlm.nih.gov/30572687" }, { "database": "PubMed", "id": "31137828", "url": "https://pubmed.ncbi.nlm.nih.gov/31137828" }, { "database": "PubMed", "id": "31311314", "url": "https://pubmed.ncbi.nlm.nih.gov/31311314" }, { "database": "PubMed", "id": "31396538", "url": "https://pubmed.ncbi.nlm.nih.gov/31396538" }, { "database": "PubMed", "id": "32875583", "url": "https://pubmed.ncbi.nlm.nih.gov/32875583" }, { "database": "PubMed", "id": "33723215", "url": "https://pubmed.ncbi.nlm.nih.gov/33723215" }, { "database": "PubMed", "id": "35656886", "url": "https://pubmed.ncbi.nlm.nih.gov/35656886" }, { "database": "PubMed", "id": "18498745", "url": "https://pubmed.ncbi.nlm.nih.gov/18498745" } ], "site_lbl": "Ser307", "uniprot_canonical_ac": "P35568-1" } ], "record_id": "pubmed.15582605", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Human insulin receptor substrate-1 (IRS-1) polymorphism G972R causes IRS-1 to associate with the insulin receptor and inhibit receptor autophosphorylation.", "journal": "J. Biol. Chem.", "date": "2005", "authors": "McGettrick Aileen J, Feener Edward P, Kahn C Ronald", "reference": { "type": "PubMed", "id": "15590636", "url": "https://pubmed.ncbi.nlm.nih.gov/15590636" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.15590636", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Insulin resistance in the skeletal muscle of women with PCOS involves intrinsic and acquired defects in insulin signaling.", "journal": "American journal of physiology. Endocrinology and metabolism", "date": "2005", "authors": "Corbould A, Kim YB, Youngren JF, Pender C, Kahn BB, Lee A, Dunaif A", "reference": { "type": "PubMed", "id": "15613682", "url": "https://pubmed.ncbi.nlm.nih.gov/15613682" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 312, "end_pos": 312, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by IKKB, MAPK8 and RPS6KB1", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "12351658", "url": "https://pubmed.ncbi.nlm.nih.gov/12351658" }, { "database": "PubMed", "id": "12510059", "url": "https://pubmed.ncbi.nlm.nih.gov/12510059" }, { "database": "PubMed", "id": "14769130", "url": "https://pubmed.ncbi.nlm.nih.gov/14769130" }, { "database": "PubMed", "id": "15044323", "url": "https://pubmed.ncbi.nlm.nih.gov/15044323" }, { "database": "PubMed", "id": "15613682", "url": "https://pubmed.ncbi.nlm.nih.gov/15613682" }, { "database": "PubMed", "id": "15713122", "url": "https://pubmed.ncbi.nlm.nih.gov/15713122" }, { "database": "PubMed", "id": "15952059", "url": "https://pubmed.ncbi.nlm.nih.gov/15952059" }, { "database": "PubMed", "id": "16123357", "url": "https://pubmed.ncbi.nlm.nih.gov/16123357" }, { "database": "PubMed", "id": "16284649", "url": "https://pubmed.ncbi.nlm.nih.gov/16284649" }, { "database": "PubMed", "id": "16505239", "url": "https://pubmed.ncbi.nlm.nih.gov/16505239" }, { "database": "PubMed", "id": "16505244", "url": "https://pubmed.ncbi.nlm.nih.gov/16505244" }, { "database": "PubMed", "id": "16516141", "url": "https://pubmed.ncbi.nlm.nih.gov/16516141" }, { "database": "PubMed", "id": "16960890", "url": "https://pubmed.ncbi.nlm.nih.gov/16960890" }, { "database": "PubMed", "id": "17204522", "url": "https://pubmed.ncbi.nlm.nih.gov/17204522" }, { "database": "PubMed", "id": "17242212", "url": "https://pubmed.ncbi.nlm.nih.gov/17242212" }, { "database": "PubMed", "id": "17360977", "url": "https://pubmed.ncbi.nlm.nih.gov/17360977" }, { "database": "PubMed", "id": "17647275", "url": "https://pubmed.ncbi.nlm.nih.gov/17647275" }, { "database": "PubMed", "id": "18160431", "url": "https://pubmed.ncbi.nlm.nih.gov/18160431" }, { "database": "PubMed", "id": "19501568", "url": "https://pubmed.ncbi.nlm.nih.gov/19501568" }, { "database": "PubMed", "id": "19567513", "url": "https://pubmed.ncbi.nlm.nih.gov/19567513" }, { "database": "PubMed", "id": "19593406", "url": "https://pubmed.ncbi.nlm.nih.gov/19593406" }, { "database": "PubMed", "id": "20393162", "url": "https://pubmed.ncbi.nlm.nih.gov/20393162" }, { "database": "PubMed", "id": "20685959", "url": "https://pubmed.ncbi.nlm.nih.gov/20685959" }, { "database": "PubMed", "id": "20863384", "url": "https://pubmed.ncbi.nlm.nih.gov/20863384" }, { "database": "PubMed", "id": "21040800", "url": "https://pubmed.ncbi.nlm.nih.gov/21040800" }, { "database": "PubMed", "id": "21252690", "url": "https://pubmed.ncbi.nlm.nih.gov/21252690" }, { "database": "PubMed", "id": "21589939", "url": "https://pubmed.ncbi.nlm.nih.gov/21589939" }, { "database": "PubMed", "id": "21852229", "url": "https://pubmed.ncbi.nlm.nih.gov/21852229" }, { "database": "PubMed", "id": "21937042", "url": "https://pubmed.ncbi.nlm.nih.gov/21937042" }, { "database": "PubMed", "id": "22348058", "url": "https://pubmed.ncbi.nlm.nih.gov/22348058" }, { "database": "PubMed", "id": "22457223", "url": "https://pubmed.ncbi.nlm.nih.gov/22457223" }, { "database": "PubMed", "id": "22862962", "url": "https://pubmed.ncbi.nlm.nih.gov/22862962" }, { "database": "PubMed", "id": "25580119", "url": "https://pubmed.ncbi.nlm.nih.gov/25580119" }, { "database": "PubMed", "id": "27207509", "url": "https://pubmed.ncbi.nlm.nih.gov/27207509" }, { "database": "PubMed", "id": "27340831", "url": "https://pubmed.ncbi.nlm.nih.gov/27340831" }, { "database": "PubMed", "id": "32536688", "url": "https://pubmed.ncbi.nlm.nih.gov/32536688" }, { "database": "PubMed", "id": "33173197", "url": "https://pubmed.ncbi.nlm.nih.gov/33173197" }, { "database": "PubMed", "id": "35833836", "url": "https://pubmed.ncbi.nlm.nih.gov/35833836" }, { "database": "PubMed", "id": "18498745", "url": "https://pubmed.ncbi.nlm.nih.gov/18498745" } ], "site_lbl": "Ser312", "uniprot_canonical_ac": "P35568-1" } ], "record_id": "pubmed.15613682", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Mechanism of feedback regulation of insulin receptor substrate-1 phosphorylation in primary adipocytes.", "journal": "The Biochemical journal", "date": "2005", "authors": "Hers I, Tavare JM", "reference": { "type": "PubMed", "id": "15713122", "url": "https://pubmed.ncbi.nlm.nih.gov/15713122" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 312, "end_pos": 312, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by IKKB, MAPK8 and RPS6KB1", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "12351658", "url": "https://pubmed.ncbi.nlm.nih.gov/12351658" }, { "database": "PubMed", "id": "12510059", "url": "https://pubmed.ncbi.nlm.nih.gov/12510059" }, { "database": "PubMed", "id": "14769130", "url": "https://pubmed.ncbi.nlm.nih.gov/14769130" }, { "database": "PubMed", "id": "15044323", "url": "https://pubmed.ncbi.nlm.nih.gov/15044323" }, { "database": "PubMed", "id": "15613682", "url": "https://pubmed.ncbi.nlm.nih.gov/15613682" }, { "database": "PubMed", "id": "15713122", "url": "https://pubmed.ncbi.nlm.nih.gov/15713122" }, { "database": "PubMed", "id": "15952059", "url": "https://pubmed.ncbi.nlm.nih.gov/15952059" }, { "database": "PubMed", "id": "16123357", "url": "https://pubmed.ncbi.nlm.nih.gov/16123357" }, { "database": "PubMed", "id": "16284649", "url": "https://pubmed.ncbi.nlm.nih.gov/16284649" }, { "database": "PubMed", "id": "16505239", "url": "https://pubmed.ncbi.nlm.nih.gov/16505239" }, { "database": "PubMed", "id": "16505244", "url": "https://pubmed.ncbi.nlm.nih.gov/16505244" }, { "database": "PubMed", "id": "16516141", "url": "https://pubmed.ncbi.nlm.nih.gov/16516141" }, { "database": "PubMed", "id": "16960890", "url": "https://pubmed.ncbi.nlm.nih.gov/16960890" }, { "database": "PubMed", "id": "17204522", "url": "https://pubmed.ncbi.nlm.nih.gov/17204522" }, { "database": "PubMed", "id": "17242212", "url": "https://pubmed.ncbi.nlm.nih.gov/17242212" }, { "database": "PubMed", "id": "17360977", "url": "https://pubmed.ncbi.nlm.nih.gov/17360977" }, { "database": "PubMed", "id": "17647275", "url": "https://pubmed.ncbi.nlm.nih.gov/17647275" }, { "database": "PubMed", "id": "18160431", "url": "https://pubmed.ncbi.nlm.nih.gov/18160431" }, { "database": "PubMed", "id": "19501568", "url": "https://pubmed.ncbi.nlm.nih.gov/19501568" }, { "database": "PubMed", "id": "19567513", "url": "https://pubmed.ncbi.nlm.nih.gov/19567513" }, { "database": "PubMed", "id": "19593406", "url": "https://pubmed.ncbi.nlm.nih.gov/19593406" }, { "database": "PubMed", "id": "20393162", "url": "https://pubmed.ncbi.nlm.nih.gov/20393162" }, { "database": "PubMed", "id": "20685959", "url": "https://pubmed.ncbi.nlm.nih.gov/20685959" }, { "database": "PubMed", "id": "20863384", "url": "https://pubmed.ncbi.nlm.nih.gov/20863384" }, { "database": "PubMed", "id": "21040800", "url": "https://pubmed.ncbi.nlm.nih.gov/21040800" }, { "database": "PubMed", "id": "21252690", "url": "https://pubmed.ncbi.nlm.nih.gov/21252690" }, { "database": "PubMed", "id": "21589939", "url": "https://pubmed.ncbi.nlm.nih.gov/21589939" }, { "database": "PubMed", "id": "21852229", "url": "https://pubmed.ncbi.nlm.nih.gov/21852229" }, { "database": "PubMed", "id": "21937042", "url": "https://pubmed.ncbi.nlm.nih.gov/21937042" }, { "database": "PubMed", "id": "22348058", "url": "https://pubmed.ncbi.nlm.nih.gov/22348058" }, { "database": "PubMed", "id": "22457223", "url": "https://pubmed.ncbi.nlm.nih.gov/22457223" }, { "database": "PubMed", "id": "22862962", "url": "https://pubmed.ncbi.nlm.nih.gov/22862962" }, { "database": "PubMed", "id": "25580119", "url": "https://pubmed.ncbi.nlm.nih.gov/25580119" }, { "database": "PubMed", "id": "27207509", "url": "https://pubmed.ncbi.nlm.nih.gov/27207509" }, { "database": "PubMed", "id": "27340831", "url": "https://pubmed.ncbi.nlm.nih.gov/27340831" }, { "database": "PubMed", "id": "32536688", "url": "https://pubmed.ncbi.nlm.nih.gov/32536688" }, { "database": "PubMed", "id": "33173197", "url": "https://pubmed.ncbi.nlm.nih.gov/33173197" }, { "database": "PubMed", "id": "35833836", "url": "https://pubmed.ncbi.nlm.nih.gov/35833836" }, { "database": "PubMed", "id": "18498745", "url": "https://pubmed.ncbi.nlm.nih.gov/18498745" } ], "site_lbl": "Ser312", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 616, "end_pos": 616, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "16354680", "url": "https://pubmed.ncbi.nlm.nih.gov/16354680" }, { "database": "PubMed", "id": "8626671", "url": "https://pubmed.ncbi.nlm.nih.gov/8626671" }, { "database": "PubMed", "id": "14769130", "url": "https://pubmed.ncbi.nlm.nih.gov/14769130" }, { "database": "PubMed", "id": "15044323", "url": "https://pubmed.ncbi.nlm.nih.gov/15044323" }, { "database": "PubMed", "id": "15713122", "url": "https://pubmed.ncbi.nlm.nih.gov/15713122" }, { "database": "PubMed", "id": "17242212", "url": "https://pubmed.ncbi.nlm.nih.gov/17242212" }, { "database": "PubMed", "id": "17360977", "url": "https://pubmed.ncbi.nlm.nih.gov/17360977" }, { "database": "PubMed", "id": "17640984", "url": "https://pubmed.ncbi.nlm.nih.gov/17640984" }, { "database": "PubMed", "id": "21937042", "url": "https://pubmed.ncbi.nlm.nih.gov/21937042" }, { "database": "PubMed", "id": "22476197", "url": "https://pubmed.ncbi.nlm.nih.gov/22476197" }, { "database": "PubMed", "id": "26297026", "url": "https://pubmed.ncbi.nlm.nih.gov/26297026" } ], "site_lbl": "Ser616", "uniprot_canonical_ac": "P35568-1" } ], "record_id": "pubmed.15713122", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Mechanisms of reactive oxygen species-dependent downregulation of insulin receptor substrate-1 by angiotensin II.", "journal": "Arteriosclerosis, thrombosis, and vascular biology", "date": "2005", "authors": "Taniyama Y, Hitomi H, Shah A, Alexander RW, Griendling KK", "reference": { "type": "PubMed", "id": "15802620", "url": "https://pubmed.ncbi.nlm.nih.gov/15802620" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 307, "end_pos": 307, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by RPS6KB1", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "11160134", "url": "https://pubmed.ncbi.nlm.nih.gov/11160134" }, { "database": "PubMed", "id": "11606564", "url": "https://pubmed.ncbi.nlm.nih.gov/11606564" }, { "database": "PubMed", "id": "12409308", "url": "https://pubmed.ncbi.nlm.nih.gov/12409308" }, { "database": "PubMed", "id": "12714600", "url": "https://pubmed.ncbi.nlm.nih.gov/12714600" }, { "database": "PubMed", "id": "12730242", "url": "https://pubmed.ncbi.nlm.nih.gov/12730242" }, { "database": "PubMed", "id": "14556646", "url": "https://pubmed.ncbi.nlm.nih.gov/14556646" }, { "database": "PubMed", "id": "14583092", "url": "https://pubmed.ncbi.nlm.nih.gov/14583092" }, { "database": "PubMed", "id": "14641015", "url": "https://pubmed.ncbi.nlm.nih.gov/14641015" }, { "database": "PubMed", "id": "14697666", "url": "https://pubmed.ncbi.nlm.nih.gov/14697666" }, { "database": "PubMed", "id": "15020250", "url": "https://pubmed.ncbi.nlm.nih.gov/15020250" }, { "database": "PubMed", "id": "15153564", "url": "https://pubmed.ncbi.nlm.nih.gov/15153564" }, { "database": "PubMed", "id": "15582605", "url": "https://pubmed.ncbi.nlm.nih.gov/15582605" }, { "database": "PubMed", "id": "15802620", "url": "https://pubmed.ncbi.nlm.nih.gov/15802620" }, { "database": "PubMed", "id": "16046301", "url": "https://pubmed.ncbi.nlm.nih.gov/16046301" }, { "database": "PubMed", "id": "16055440", "url": "https://pubmed.ncbi.nlm.nih.gov/16055440" }, { "database": "PubMed", "id": "16099428", "url": "https://pubmed.ncbi.nlm.nih.gov/16099428" }, { "database": "PubMed", "id": "16210322", "url": "https://pubmed.ncbi.nlm.nih.gov/16210322" }, { "database": "PubMed", "id": "16269459", "url": "https://pubmed.ncbi.nlm.nih.gov/16269459" }, { "database": "PubMed", "id": "16516141", "url": "https://pubmed.ncbi.nlm.nih.gov/16516141" }, { "database": "PubMed", "id": "16754954", "url": "https://pubmed.ncbi.nlm.nih.gov/16754954" }, { "database": "PubMed", "id": "16839860", "url": "https://pubmed.ncbi.nlm.nih.gov/16839860" }, { "database": "PubMed", "id": "17077083", "url": "https://pubmed.ncbi.nlm.nih.gov/17077083" }, { "database": "PubMed", "id": "17095576", "url": "https://pubmed.ncbi.nlm.nih.gov/17095576" }, { "database": "PubMed", "id": "17276034", "url": "https://pubmed.ncbi.nlm.nih.gov/17276034" }, { "database": "PubMed", "id": "17481767", "url": "https://pubmed.ncbi.nlm.nih.gov/17481767" }, { "database": "PubMed", "id": "17575262", "url": "https://pubmed.ncbi.nlm.nih.gov/17575262" }, { "database": "PubMed", "id": "18187553", "url": "https://pubmed.ncbi.nlm.nih.gov/18187553" }, { "database": "PubMed", "id": "18372392", "url": "https://pubmed.ncbi.nlm.nih.gov/18372392" }, { "database": "PubMed", "id": "18380932", "url": "https://pubmed.ncbi.nlm.nih.gov/18380932" }, { "database": "PubMed", "id": "18496818", "url": "https://pubmed.ncbi.nlm.nih.gov/18496818" }, { "database": "PubMed", "id": "18952604", "url": "https://pubmed.ncbi.nlm.nih.gov/18952604" }, { "database": "PubMed", "id": "19095745", "url": "https://pubmed.ncbi.nlm.nih.gov/19095745" }, { "database": "PubMed", "id": "19524129", "url": "https://pubmed.ncbi.nlm.nih.gov/19524129" }, { "database": "PubMed", "id": "19897715", "url": "https://pubmed.ncbi.nlm.nih.gov/19897715" }, { "database": "PubMed", "id": "20351777", "url": "https://pubmed.ncbi.nlm.nih.gov/20351777" }, { "database": "PubMed", "id": "20382011", "url": "https://pubmed.ncbi.nlm.nih.gov/20382011" }, { "database": "PubMed", "id": "20384568", "url": "https://pubmed.ncbi.nlm.nih.gov/20384568" }, { "database": "PubMed", "id": "20541543", "url": "https://pubmed.ncbi.nlm.nih.gov/20541543" }, { "database": "PubMed", "id": "20587749", "url": "https://pubmed.ncbi.nlm.nih.gov/20587749" }, { "database": "PubMed", "id": "20594161", "url": "https://pubmed.ncbi.nlm.nih.gov/20594161" }, { "database": "PubMed", "id": "20594757", "url": "https://pubmed.ncbi.nlm.nih.gov/20594757" }, { "database": "PubMed", "id": "20702573", "url": "https://pubmed.ncbi.nlm.nih.gov/20702573" }, { "database": "PubMed", "id": "21119656", "url": "https://pubmed.ncbi.nlm.nih.gov/21119656" }, { "database": "PubMed", "id": "21478152", "url": "https://pubmed.ncbi.nlm.nih.gov/21478152" }, { "database": "PubMed", "id": "21505982", "url": "https://pubmed.ncbi.nlm.nih.gov/21505982" }, { "database": "PubMed", "id": "21786209", "url": "https://pubmed.ncbi.nlm.nih.gov/21786209" }, { "database": "PubMed", "id": "21852229", "url": "https://pubmed.ncbi.nlm.nih.gov/21852229" }, { "database": "PubMed", "id": "21900690", "url": "https://pubmed.ncbi.nlm.nih.gov/21900690" }, { "database": "PubMed", "id": "22046423", "url": "https://pubmed.ncbi.nlm.nih.gov/22046423" }, { "database": "PubMed", "id": "22227580", "url": "https://pubmed.ncbi.nlm.nih.gov/22227580" }, { "database": "PubMed", "id": "22266116", "url": "https://pubmed.ncbi.nlm.nih.gov/22266116" }, { "database": "PubMed", "id": "22328823", "url": "https://pubmed.ncbi.nlm.nih.gov/22328823" }, { "database": "PubMed", "id": "22348058", "url": "https://pubmed.ncbi.nlm.nih.gov/22348058" }, { "database": "PubMed", "id": "22491740", "url": "https://pubmed.ncbi.nlm.nih.gov/22491740" }, { "database": "PubMed", "id": "22728372", "url": "https://pubmed.ncbi.nlm.nih.gov/22728372" }, { "database": "PubMed", "id": "22766331", "url": "https://pubmed.ncbi.nlm.nih.gov/22766331" }, { "database": "PubMed", "id": "23095254", "url": "https://pubmed.ncbi.nlm.nih.gov/23095254" }, { "database": "PubMed", "id": "23174405", "url": "https://pubmed.ncbi.nlm.nih.gov/23174405" }, { "database": "PubMed", "id": "23182460", "url": "https://pubmed.ncbi.nlm.nih.gov/23182460" }, { "database": "PubMed", "id": "23481042", "url": "https://pubmed.ncbi.nlm.nih.gov/23481042" }, { "database": "PubMed", "id": "23566306", "url": "https://pubmed.ncbi.nlm.nih.gov/23566306" }, { "database": "PubMed", "id": "23592917", "url": "https://pubmed.ncbi.nlm.nih.gov/23592917" }, { "database": "PubMed", "id": "23891856", "url": "https://pubmed.ncbi.nlm.nih.gov/23891856" }, { "database": "PubMed", "id": "23958494", "url": "https://pubmed.ncbi.nlm.nih.gov/23958494" }, { "database": "PubMed", "id": "24068326", "url": "https://pubmed.ncbi.nlm.nih.gov/24068326" }, { "database": "PubMed", "id": "24846082", "url": "https://pubmed.ncbi.nlm.nih.gov/24846082" }, { "database": "PubMed", "id": "25120613", "url": "https://pubmed.ncbi.nlm.nih.gov/25120613" }, { "database": "PubMed", "id": "25355439", "url": "https://pubmed.ncbi.nlm.nih.gov/25355439" }, { "database": "PubMed", "id": "25645159", "url": "https://pubmed.ncbi.nlm.nih.gov/25645159" }, { "database": "PubMed", "id": "25799226", "url": "https://pubmed.ncbi.nlm.nih.gov/25799226" }, { "database": "PubMed", "id": "26604643", "url": "https://pubmed.ncbi.nlm.nih.gov/26604643" }, { "database": "PubMed", "id": "26698173", "url": "https://pubmed.ncbi.nlm.nih.gov/26698173" }, { "database": "PubMed", "id": "26704265", "url": "https://pubmed.ncbi.nlm.nih.gov/26704265" }, { "database": "PubMed", "id": "26899161", "url": "https://pubmed.ncbi.nlm.nih.gov/26899161" }, { "database": "PubMed", "id": "26983645", "url": "https://pubmed.ncbi.nlm.nih.gov/26983645" }, { "database": "PubMed", "id": "27222060", "url": "https://pubmed.ncbi.nlm.nih.gov/27222060" }, { "database": "PubMed", "id": "27506476", "url": "https://pubmed.ncbi.nlm.nih.gov/27506476" }, { "database": "PubMed", "id": "27544192", "url": "https://pubmed.ncbi.nlm.nih.gov/27544192" }, { "database": "PubMed", "id": "27686967", "url": "https://pubmed.ncbi.nlm.nih.gov/27686967" }, { "database": "PubMed", "id": "27936435", "url": "https://pubmed.ncbi.nlm.nih.gov/27936435" }, { "database": "PubMed", "id": "28161417", "url": "https://pubmed.ncbi.nlm.nih.gov/28161417" }, { "database": "PubMed", "id": "28656239", "url": "https://pubmed.ncbi.nlm.nih.gov/28656239" }, { "database": "PubMed", "id": "28731188", "url": "https://pubmed.ncbi.nlm.nih.gov/28731188" }, { "database": "PubMed", "id": "28790390", "url": "https://pubmed.ncbi.nlm.nih.gov/28790390" }, { "database": "PubMed", "id": "28934129", "url": "https://pubmed.ncbi.nlm.nih.gov/28934129" }, { "database": "PubMed", "id": "29177868", "url": "https://pubmed.ncbi.nlm.nih.gov/29177868" }, { "database": "PubMed", "id": "29311680", "url": "https://pubmed.ncbi.nlm.nih.gov/29311680" }, { "database": "PubMed", "id": "29393871", "url": "https://pubmed.ncbi.nlm.nih.gov/29393871" }, { "database": "PubMed", "id": "29432553", "url": "https://pubmed.ncbi.nlm.nih.gov/29432553" }, { "database": "PubMed", "id": "29698741", "url": "https://pubmed.ncbi.nlm.nih.gov/29698741" }, { "database": "PubMed", "id": "29738527", "url": "https://pubmed.ncbi.nlm.nih.gov/29738527" }, { "database": "PubMed", "id": "30240640", "url": "https://pubmed.ncbi.nlm.nih.gov/30240640" }, { "database": "PubMed", "id": "30374127", "url": "https://pubmed.ncbi.nlm.nih.gov/30374127" }, { "database": "PubMed", "id": "30572687", "url": "https://pubmed.ncbi.nlm.nih.gov/30572687" }, { "database": "PubMed", "id": "31137828", "url": "https://pubmed.ncbi.nlm.nih.gov/31137828" }, { "database": "PubMed", "id": "31311314", "url": "https://pubmed.ncbi.nlm.nih.gov/31311314" }, { "database": "PubMed", "id": "31396538", "url": "https://pubmed.ncbi.nlm.nih.gov/31396538" }, { "database": "PubMed", "id": "32875583", "url": "https://pubmed.ncbi.nlm.nih.gov/32875583" }, { "database": "PubMed", "id": "33723215", "url": "https://pubmed.ncbi.nlm.nih.gov/33723215" }, { "database": "PubMed", "id": "35656886", "url": "https://pubmed.ncbi.nlm.nih.gov/35656886" }, { "database": "PubMed", "id": "18498745", "url": "https://pubmed.ncbi.nlm.nih.gov/18498745" } ], "site_lbl": "Ser307", "uniprot_canonical_ac": "P35568-1" } ], "record_id": "pubmed.15802620", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "PKCdelta and mTOR interact to regulate stress and IGF-I induced IRS-1 Ser312 phosphorylation in breast cancer cells.", "journal": "Breast cancer research and treatment", "date": "2005", "authors": "Mingo-Sion AM, Ferguson HA, Koller E, Reyland ME, Van Den Berg CL", "reference": { "type": "PubMed", "id": "15952059", "url": "https://pubmed.ncbi.nlm.nih.gov/15952059" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 312, "end_pos": 312, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by IKKB, MAPK8 and RPS6KB1", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "12351658", "url": "https://pubmed.ncbi.nlm.nih.gov/12351658" }, { "database": "PubMed", "id": "12510059", "url": "https://pubmed.ncbi.nlm.nih.gov/12510059" }, { "database": "PubMed", "id": "14769130", "url": "https://pubmed.ncbi.nlm.nih.gov/14769130" }, { "database": "PubMed", "id": "15044323", "url": "https://pubmed.ncbi.nlm.nih.gov/15044323" }, { "database": "PubMed", "id": "15613682", "url": "https://pubmed.ncbi.nlm.nih.gov/15613682" }, { "database": "PubMed", "id": "15713122", "url": "https://pubmed.ncbi.nlm.nih.gov/15713122" }, { "database": "PubMed", "id": "15952059", "url": "https://pubmed.ncbi.nlm.nih.gov/15952059" }, { "database": "PubMed", "id": "16123357", "url": "https://pubmed.ncbi.nlm.nih.gov/16123357" }, { "database": "PubMed", "id": "16284649", "url": "https://pubmed.ncbi.nlm.nih.gov/16284649" }, { "database": "PubMed", "id": "16505239", "url": "https://pubmed.ncbi.nlm.nih.gov/16505239" }, { "database": "PubMed", "id": "16505244", "url": "https://pubmed.ncbi.nlm.nih.gov/16505244" }, { "database": "PubMed", "id": "16516141", "url": "https://pubmed.ncbi.nlm.nih.gov/16516141" }, { "database": "PubMed", "id": "16960890", "url": "https://pubmed.ncbi.nlm.nih.gov/16960890" }, { "database": "PubMed", "id": "17204522", "url": "https://pubmed.ncbi.nlm.nih.gov/17204522" }, { "database": "PubMed", "id": "17242212", "url": "https://pubmed.ncbi.nlm.nih.gov/17242212" }, { "database": "PubMed", "id": "17360977", "url": "https://pubmed.ncbi.nlm.nih.gov/17360977" }, { "database": "PubMed", "id": "17647275", "url": "https://pubmed.ncbi.nlm.nih.gov/17647275" }, { "database": "PubMed", "id": "18160431", "url": "https://pubmed.ncbi.nlm.nih.gov/18160431" }, { "database": "PubMed", "id": "19501568", "url": "https://pubmed.ncbi.nlm.nih.gov/19501568" }, { "database": "PubMed", "id": "19567513", "url": "https://pubmed.ncbi.nlm.nih.gov/19567513" }, { "database": "PubMed", "id": "19593406", "url": "https://pubmed.ncbi.nlm.nih.gov/19593406" }, { "database": "PubMed", "id": "20393162", "url": "https://pubmed.ncbi.nlm.nih.gov/20393162" }, { "database": "PubMed", "id": "20685959", "url": "https://pubmed.ncbi.nlm.nih.gov/20685959" }, { "database": "PubMed", "id": "20863384", "url": "https://pubmed.ncbi.nlm.nih.gov/20863384" }, { "database": "PubMed", "id": "21040800", "url": "https://pubmed.ncbi.nlm.nih.gov/21040800" }, { "database": "PubMed", "id": "21252690", "url": "https://pubmed.ncbi.nlm.nih.gov/21252690" }, { "database": "PubMed", "id": "21589939", "url": "https://pubmed.ncbi.nlm.nih.gov/21589939" }, { "database": "PubMed", "id": "21852229", "url": "https://pubmed.ncbi.nlm.nih.gov/21852229" }, { "database": "PubMed", "id": "21937042", "url": "https://pubmed.ncbi.nlm.nih.gov/21937042" }, { "database": "PubMed", "id": "22348058", "url": "https://pubmed.ncbi.nlm.nih.gov/22348058" }, { "database": "PubMed", "id": "22457223", "url": "https://pubmed.ncbi.nlm.nih.gov/22457223" }, { "database": "PubMed", "id": "22862962", "url": "https://pubmed.ncbi.nlm.nih.gov/22862962" }, { "database": "PubMed", "id": "25580119", "url": "https://pubmed.ncbi.nlm.nih.gov/25580119" }, { "database": "PubMed", "id": "27207509", "url": "https://pubmed.ncbi.nlm.nih.gov/27207509" }, { "database": "PubMed", "id": "27340831", "url": "https://pubmed.ncbi.nlm.nih.gov/27340831" }, { "database": "PubMed", "id": "32536688", "url": "https://pubmed.ncbi.nlm.nih.gov/32536688" }, { "database": "PubMed", "id": "33173197", "url": "https://pubmed.ncbi.nlm.nih.gov/33173197" }, { "database": "PubMed", "id": "35833836", "url": "https://pubmed.ncbi.nlm.nih.gov/35833836" }, { "database": "PubMed", "id": "18498745", "url": "https://pubmed.ncbi.nlm.nih.gov/18498745" } ], "site_lbl": "Ser312", "uniprot_canonical_ac": "P35568-1" } ], "record_id": "pubmed.15952059", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Identification of insulin receptor substrate 1 serine/threonine phosphorylation sites using mass spectrometry analysis: regulatory role of serine 1223.", "journal": "Endocrinology", "date": "2005", "authors": "Luo M, Reyna S, Wang L, Yi Z, Carroll C, Dong LQ, Langlais P, Weintraub ST, Mandarino LJ", "reference": { "type": "PubMed", "id": "16020478", "url": "https://pubmed.ncbi.nlm.nih.gov/16020478" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 1223, "end_pos": 1223, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "16131083", "url": "https://pubmed.ncbi.nlm.nih.gov/16131083" }, { "database": "PubMed", "id": "16020478", "url": "https://pubmed.ncbi.nlm.nih.gov/16020478" }, { "database": "PubMed", "id": "17360977", "url": "https://pubmed.ncbi.nlm.nih.gov/17360977" } ], "site_lbl": "Ser1223", "uniprot_canonical_ac": "P35568-1" } ], "record_id": "pubmed.16020478", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Increased p85/55/50 expression and decreased phosphotidylinositol 3-kinase activity in insulin-resistant human skeletal muscle.", "journal": "Diabetes", "date": "2005", "authors": "Bandyopadhyay GK, Yu JG, Ofrecio J, Olefsky JM", "reference": { "type": "PubMed", "id": "16046301", "url": "https://pubmed.ncbi.nlm.nih.gov/16046301" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 307, "end_pos": 307, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by RPS6KB1", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "11160134", "url": "https://pubmed.ncbi.nlm.nih.gov/11160134" }, { "database": "PubMed", "id": "11606564", "url": "https://pubmed.ncbi.nlm.nih.gov/11606564" }, { "database": "PubMed", "id": "12409308", "url": "https://pubmed.ncbi.nlm.nih.gov/12409308" }, { "database": "PubMed", "id": "12714600", "url": "https://pubmed.ncbi.nlm.nih.gov/12714600" }, { "database": "PubMed", "id": "12730242", "url": "https://pubmed.ncbi.nlm.nih.gov/12730242" }, { "database": "PubMed", "id": "14556646", "url": "https://pubmed.ncbi.nlm.nih.gov/14556646" }, { "database": "PubMed", "id": "14583092", "url": "https://pubmed.ncbi.nlm.nih.gov/14583092" }, { "database": "PubMed", "id": "14641015", "url": "https://pubmed.ncbi.nlm.nih.gov/14641015" }, { "database": "PubMed", "id": "14697666", "url": "https://pubmed.ncbi.nlm.nih.gov/14697666" }, { "database": "PubMed", "id": "15020250", "url": "https://pubmed.ncbi.nlm.nih.gov/15020250" }, { "database": "PubMed", "id": "15153564", "url": "https://pubmed.ncbi.nlm.nih.gov/15153564" }, { "database": "PubMed", "id": "15582605", "url": "https://pubmed.ncbi.nlm.nih.gov/15582605" }, { "database": "PubMed", "id": "15802620", "url": "https://pubmed.ncbi.nlm.nih.gov/15802620" }, { "database": "PubMed", "id": "16046301", "url": "https://pubmed.ncbi.nlm.nih.gov/16046301" }, { "database": "PubMed", "id": "16055440", "url": "https://pubmed.ncbi.nlm.nih.gov/16055440" }, { "database": "PubMed", "id": "16099428", "url": "https://pubmed.ncbi.nlm.nih.gov/16099428" }, { "database": "PubMed", "id": "16210322", "url": "https://pubmed.ncbi.nlm.nih.gov/16210322" }, { "database": "PubMed", "id": "16269459", "url": "https://pubmed.ncbi.nlm.nih.gov/16269459" }, { "database": "PubMed", "id": "16516141", "url": "https://pubmed.ncbi.nlm.nih.gov/16516141" }, { "database": "PubMed", "id": "16754954", "url": "https://pubmed.ncbi.nlm.nih.gov/16754954" }, { "database": "PubMed", "id": "16839860", "url": "https://pubmed.ncbi.nlm.nih.gov/16839860" }, { "database": "PubMed", "id": "17077083", "url": "https://pubmed.ncbi.nlm.nih.gov/17077083" }, { "database": "PubMed", "id": "17095576", "url": "https://pubmed.ncbi.nlm.nih.gov/17095576" }, { "database": "PubMed", "id": "17276034", "url": "https://pubmed.ncbi.nlm.nih.gov/17276034" }, { "database": "PubMed", "id": "17481767", "url": "https://pubmed.ncbi.nlm.nih.gov/17481767" }, { "database": "PubMed", "id": "17575262", "url": "https://pubmed.ncbi.nlm.nih.gov/17575262" }, { "database": "PubMed", "id": "18187553", "url": "https://pubmed.ncbi.nlm.nih.gov/18187553" }, { "database": "PubMed", "id": "18372392", "url": "https://pubmed.ncbi.nlm.nih.gov/18372392" }, { "database": "PubMed", "id": "18380932", "url": "https://pubmed.ncbi.nlm.nih.gov/18380932" }, { "database": "PubMed", "id": "18496818", "url": "https://pubmed.ncbi.nlm.nih.gov/18496818" }, { "database": "PubMed", "id": "18952604", "url": "https://pubmed.ncbi.nlm.nih.gov/18952604" }, { "database": "PubMed", "id": "19095745", "url": "https://pubmed.ncbi.nlm.nih.gov/19095745" }, { "database": "PubMed", "id": "19524129", "url": "https://pubmed.ncbi.nlm.nih.gov/19524129" }, { "database": "PubMed", "id": "19897715", "url": "https://pubmed.ncbi.nlm.nih.gov/19897715" }, { "database": "PubMed", "id": "20351777", "url": "https://pubmed.ncbi.nlm.nih.gov/20351777" }, { "database": "PubMed", "id": "20382011", "url": "https://pubmed.ncbi.nlm.nih.gov/20382011" }, { "database": "PubMed", "id": "20384568", "url": "https://pubmed.ncbi.nlm.nih.gov/20384568" }, { "database": "PubMed", "id": "20541543", "url": "https://pubmed.ncbi.nlm.nih.gov/20541543" }, { "database": "PubMed", "id": "20587749", "url": "https://pubmed.ncbi.nlm.nih.gov/20587749" }, { "database": "PubMed", "id": "20594161", "url": "https://pubmed.ncbi.nlm.nih.gov/20594161" }, { "database": "PubMed", "id": "20594757", "url": "https://pubmed.ncbi.nlm.nih.gov/20594757" }, { "database": "PubMed", "id": "20702573", "url": "https://pubmed.ncbi.nlm.nih.gov/20702573" }, { "database": "PubMed", "id": "21119656", "url": "https://pubmed.ncbi.nlm.nih.gov/21119656" }, { "database": "PubMed", "id": "21478152", "url": "https://pubmed.ncbi.nlm.nih.gov/21478152" }, { "database": "PubMed", "id": "21505982", "url": "https://pubmed.ncbi.nlm.nih.gov/21505982" }, { "database": "PubMed", "id": "21786209", "url": "https://pubmed.ncbi.nlm.nih.gov/21786209" }, { "database": "PubMed", "id": "21852229", "url": "https://pubmed.ncbi.nlm.nih.gov/21852229" }, { "database": "PubMed", "id": "21900690", "url": "https://pubmed.ncbi.nlm.nih.gov/21900690" }, { "database": "PubMed", "id": "22046423", "url": "https://pubmed.ncbi.nlm.nih.gov/22046423" }, { "database": "PubMed", "id": "22227580", "url": "https://pubmed.ncbi.nlm.nih.gov/22227580" }, { "database": "PubMed", "id": "22266116", "url": "https://pubmed.ncbi.nlm.nih.gov/22266116" }, { "database": "PubMed", "id": "22328823", "url": "https://pubmed.ncbi.nlm.nih.gov/22328823" }, { "database": "PubMed", "id": "22348058", "url": "https://pubmed.ncbi.nlm.nih.gov/22348058" }, { "database": "PubMed", "id": "22491740", "url": "https://pubmed.ncbi.nlm.nih.gov/22491740" }, { "database": "PubMed", "id": "22728372", "url": "https://pubmed.ncbi.nlm.nih.gov/22728372" }, { "database": "PubMed", "id": "22766331", "url": "https://pubmed.ncbi.nlm.nih.gov/22766331" }, { "database": "PubMed", "id": "23095254", "url": "https://pubmed.ncbi.nlm.nih.gov/23095254" }, { "database": "PubMed", "id": "23174405", "url": "https://pubmed.ncbi.nlm.nih.gov/23174405" }, { "database": "PubMed", "id": "23182460", "url": "https://pubmed.ncbi.nlm.nih.gov/23182460" }, { "database": "PubMed", "id": "23481042", "url": "https://pubmed.ncbi.nlm.nih.gov/23481042" }, { "database": "PubMed", "id": "23566306", "url": "https://pubmed.ncbi.nlm.nih.gov/23566306" }, { "database": "PubMed", "id": "23592917", "url": "https://pubmed.ncbi.nlm.nih.gov/23592917" }, { "database": "PubMed", "id": "23891856", "url": "https://pubmed.ncbi.nlm.nih.gov/23891856" }, { "database": "PubMed", "id": "23958494", "url": "https://pubmed.ncbi.nlm.nih.gov/23958494" }, { "database": "PubMed", "id": "24068326", "url": "https://pubmed.ncbi.nlm.nih.gov/24068326" }, { "database": "PubMed", "id": "24846082", "url": "https://pubmed.ncbi.nlm.nih.gov/24846082" }, { "database": "PubMed", "id": "25120613", "url": "https://pubmed.ncbi.nlm.nih.gov/25120613" }, { "database": "PubMed", "id": "25355439", "url": "https://pubmed.ncbi.nlm.nih.gov/25355439" }, { "database": "PubMed", "id": "25645159", "url": "https://pubmed.ncbi.nlm.nih.gov/25645159" }, { "database": "PubMed", "id": "25799226", "url": "https://pubmed.ncbi.nlm.nih.gov/25799226" }, { "database": "PubMed", "id": "26604643", "url": "https://pubmed.ncbi.nlm.nih.gov/26604643" }, { "database": "PubMed", "id": "26698173", "url": "https://pubmed.ncbi.nlm.nih.gov/26698173" }, { "database": "PubMed", "id": "26704265", "url": "https://pubmed.ncbi.nlm.nih.gov/26704265" }, { "database": "PubMed", "id": "26899161", "url": "https://pubmed.ncbi.nlm.nih.gov/26899161" }, { "database": "PubMed", "id": "26983645", "url": "https://pubmed.ncbi.nlm.nih.gov/26983645" }, { "database": "PubMed", "id": "27222060", "url": "https://pubmed.ncbi.nlm.nih.gov/27222060" }, { "database": "PubMed", "id": "27506476", "url": "https://pubmed.ncbi.nlm.nih.gov/27506476" }, { "database": "PubMed", "id": "27544192", "url": "https://pubmed.ncbi.nlm.nih.gov/27544192" }, { "database": "PubMed", "id": "27686967", "url": "https://pubmed.ncbi.nlm.nih.gov/27686967" }, { "database": "PubMed", "id": "27936435", "url": "https://pubmed.ncbi.nlm.nih.gov/27936435" }, { "database": "PubMed", "id": "28161417", "url": "https://pubmed.ncbi.nlm.nih.gov/28161417" }, { "database": "PubMed", "id": "28656239", "url": "https://pubmed.ncbi.nlm.nih.gov/28656239" }, { "database": "PubMed", "id": "28731188", "url": "https://pubmed.ncbi.nlm.nih.gov/28731188" }, { "database": "PubMed", "id": "28790390", "url": "https://pubmed.ncbi.nlm.nih.gov/28790390" }, { "database": "PubMed", "id": "28934129", "url": "https://pubmed.ncbi.nlm.nih.gov/28934129" }, { "database": "PubMed", "id": "29177868", "url": "https://pubmed.ncbi.nlm.nih.gov/29177868" }, { "database": "PubMed", "id": "29311680", "url": "https://pubmed.ncbi.nlm.nih.gov/29311680" }, { "database": "PubMed", "id": "29393871", "url": "https://pubmed.ncbi.nlm.nih.gov/29393871" }, { "database": "PubMed", "id": "29432553", "url": "https://pubmed.ncbi.nlm.nih.gov/29432553" }, { "database": "PubMed", "id": "29698741", "url": "https://pubmed.ncbi.nlm.nih.gov/29698741" }, { "database": "PubMed", "id": "29738527", "url": "https://pubmed.ncbi.nlm.nih.gov/29738527" }, { "database": "PubMed", "id": "30240640", "url": "https://pubmed.ncbi.nlm.nih.gov/30240640" }, { "database": "PubMed", "id": "30374127", "url": "https://pubmed.ncbi.nlm.nih.gov/30374127" }, { "database": "PubMed", "id": "30572687", "url": "https://pubmed.ncbi.nlm.nih.gov/30572687" }, { "database": "PubMed", "id": "31137828", "url": "https://pubmed.ncbi.nlm.nih.gov/31137828" }, { "database": "PubMed", "id": "31311314", "url": "https://pubmed.ncbi.nlm.nih.gov/31311314" }, { "database": "PubMed", "id": "31396538", "url": "https://pubmed.ncbi.nlm.nih.gov/31396538" }, { "database": "PubMed", "id": "32875583", "url": "https://pubmed.ncbi.nlm.nih.gov/32875583" }, { "database": "PubMed", "id": "33723215", "url": "https://pubmed.ncbi.nlm.nih.gov/33723215" }, { "database": "PubMed", "id": "35656886", "url": "https://pubmed.ncbi.nlm.nih.gov/35656886" }, { "database": "PubMed", "id": "18498745", "url": "https://pubmed.ncbi.nlm.nih.gov/18498745" } ], "site_lbl": "Ser307", "uniprot_canonical_ac": "P35568-1" } ], "record_id": "pubmed.16046301", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Roles of mTOR and JNK in serine phosphorylation, translocation, and degradation of IRS-1.", "journal": "Biochemical and biophysical research communications", "date": "2005", "authors": "Hiratani K, Haruta T, Tani A, Kawahara J, Usui I, Kobayashi M", "reference": { "type": "PubMed", "id": "16099428", "url": "https://pubmed.ncbi.nlm.nih.gov/16099428" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 307, "end_pos": 307, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by RPS6KB1", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "11160134", "url": "https://pubmed.ncbi.nlm.nih.gov/11160134" }, { "database": "PubMed", "id": "11606564", "url": "https://pubmed.ncbi.nlm.nih.gov/11606564" }, { "database": "PubMed", "id": "12409308", "url": "https://pubmed.ncbi.nlm.nih.gov/12409308" }, { "database": "PubMed", "id": "12714600", "url": "https://pubmed.ncbi.nlm.nih.gov/12714600" }, { "database": "PubMed", "id": "12730242", "url": "https://pubmed.ncbi.nlm.nih.gov/12730242" }, { "database": "PubMed", "id": "14556646", "url": "https://pubmed.ncbi.nlm.nih.gov/14556646" }, { "database": "PubMed", "id": "14583092", "url": "https://pubmed.ncbi.nlm.nih.gov/14583092" }, { "database": "PubMed", "id": "14641015", "url": "https://pubmed.ncbi.nlm.nih.gov/14641015" }, { "database": "PubMed", "id": "14697666", "url": "https://pubmed.ncbi.nlm.nih.gov/14697666" }, { "database": "PubMed", "id": "15020250", "url": "https://pubmed.ncbi.nlm.nih.gov/15020250" }, { "database": "PubMed", "id": "15153564", "url": "https://pubmed.ncbi.nlm.nih.gov/15153564" }, { "database": "PubMed", "id": "15582605", "url": "https://pubmed.ncbi.nlm.nih.gov/15582605" }, { "database": "PubMed", "id": "15802620", "url": "https://pubmed.ncbi.nlm.nih.gov/15802620" }, { "database": "PubMed", "id": "16046301", "url": "https://pubmed.ncbi.nlm.nih.gov/16046301" }, { "database": "PubMed", "id": "16055440", "url": "https://pubmed.ncbi.nlm.nih.gov/16055440" }, { "database": "PubMed", "id": "16099428", "url": "https://pubmed.ncbi.nlm.nih.gov/16099428" }, { "database": "PubMed", "id": "16210322", "url": "https://pubmed.ncbi.nlm.nih.gov/16210322" }, { "database": "PubMed", "id": "16269459", "url": "https://pubmed.ncbi.nlm.nih.gov/16269459" }, { "database": "PubMed", "id": "16516141", "url": "https://pubmed.ncbi.nlm.nih.gov/16516141" }, { "database": "PubMed", "id": "16754954", "url": "https://pubmed.ncbi.nlm.nih.gov/16754954" }, { "database": "PubMed", "id": "16839860", "url": "https://pubmed.ncbi.nlm.nih.gov/16839860" }, { "database": "PubMed", "id": "17077083", "url": "https://pubmed.ncbi.nlm.nih.gov/17077083" }, { "database": "PubMed", "id": "17095576", "url": "https://pubmed.ncbi.nlm.nih.gov/17095576" }, { "database": "PubMed", "id": "17276034", "url": "https://pubmed.ncbi.nlm.nih.gov/17276034" }, { "database": "PubMed", "id": "17481767", "url": "https://pubmed.ncbi.nlm.nih.gov/17481767" }, { "database": "PubMed", "id": "17575262", "url": "https://pubmed.ncbi.nlm.nih.gov/17575262" }, { "database": "PubMed", "id": "18187553", "url": "https://pubmed.ncbi.nlm.nih.gov/18187553" }, { "database": "PubMed", "id": "18372392", "url": "https://pubmed.ncbi.nlm.nih.gov/18372392" }, { "database": "PubMed", "id": "18380932", "url": "https://pubmed.ncbi.nlm.nih.gov/18380932" }, { "database": "PubMed", "id": "18496818", "url": "https://pubmed.ncbi.nlm.nih.gov/18496818" }, { "database": "PubMed", "id": "18952604", "url": "https://pubmed.ncbi.nlm.nih.gov/18952604" }, { "database": "PubMed", "id": "19095745", "url": "https://pubmed.ncbi.nlm.nih.gov/19095745" }, { "database": "PubMed", "id": "19524129", "url": "https://pubmed.ncbi.nlm.nih.gov/19524129" }, { "database": "PubMed", "id": "19897715", "url": "https://pubmed.ncbi.nlm.nih.gov/19897715" }, { "database": "PubMed", "id": "20351777", "url": "https://pubmed.ncbi.nlm.nih.gov/20351777" }, { "database": "PubMed", "id": "20382011", "url": "https://pubmed.ncbi.nlm.nih.gov/20382011" }, { "database": "PubMed", "id": "20384568", "url": "https://pubmed.ncbi.nlm.nih.gov/20384568" }, { "database": "PubMed", "id": "20541543", "url": "https://pubmed.ncbi.nlm.nih.gov/20541543" }, { "database": "PubMed", "id": "20587749", "url": "https://pubmed.ncbi.nlm.nih.gov/20587749" }, { "database": "PubMed", "id": "20594161", "url": "https://pubmed.ncbi.nlm.nih.gov/20594161" }, { "database": "PubMed", "id": "20594757", "url": "https://pubmed.ncbi.nlm.nih.gov/20594757" }, { "database": "PubMed", "id": "20702573", "url": "https://pubmed.ncbi.nlm.nih.gov/20702573" }, { "database": "PubMed", "id": "21119656", "url": "https://pubmed.ncbi.nlm.nih.gov/21119656" }, { "database": "PubMed", "id": "21478152", "url": "https://pubmed.ncbi.nlm.nih.gov/21478152" }, { "database": "PubMed", "id": "21505982", "url": "https://pubmed.ncbi.nlm.nih.gov/21505982" }, { "database": "PubMed", "id": "21786209", "url": "https://pubmed.ncbi.nlm.nih.gov/21786209" }, { "database": "PubMed", "id": "21852229", "url": "https://pubmed.ncbi.nlm.nih.gov/21852229" }, { "database": "PubMed", "id": "21900690", "url": "https://pubmed.ncbi.nlm.nih.gov/21900690" }, { "database": "PubMed", "id": "22046423", "url": "https://pubmed.ncbi.nlm.nih.gov/22046423" }, { "database": "PubMed", "id": "22227580", "url": "https://pubmed.ncbi.nlm.nih.gov/22227580" }, { "database": "PubMed", "id": "22266116", "url": "https://pubmed.ncbi.nlm.nih.gov/22266116" }, { "database": "PubMed", "id": "22328823", "url": "https://pubmed.ncbi.nlm.nih.gov/22328823" }, { "database": "PubMed", "id": "22348058", "url": "https://pubmed.ncbi.nlm.nih.gov/22348058" }, { "database": "PubMed", "id": "22491740", "url": "https://pubmed.ncbi.nlm.nih.gov/22491740" }, { "database": "PubMed", "id": "22728372", "url": "https://pubmed.ncbi.nlm.nih.gov/22728372" }, { "database": "PubMed", "id": "22766331", "url": "https://pubmed.ncbi.nlm.nih.gov/22766331" }, { "database": "PubMed", "id": "23095254", "url": "https://pubmed.ncbi.nlm.nih.gov/23095254" }, { "database": "PubMed", "id": "23174405", "url": "https://pubmed.ncbi.nlm.nih.gov/23174405" }, { "database": "PubMed", "id": "23182460", "url": "https://pubmed.ncbi.nlm.nih.gov/23182460" }, { "database": "PubMed", "id": "23481042", "url": "https://pubmed.ncbi.nlm.nih.gov/23481042" }, { "database": "PubMed", "id": "23566306", "url": "https://pubmed.ncbi.nlm.nih.gov/23566306" }, { "database": "PubMed", "id": "23592917", "url": "https://pubmed.ncbi.nlm.nih.gov/23592917" }, { "database": "PubMed", "id": "23891856", "url": "https://pubmed.ncbi.nlm.nih.gov/23891856" }, { "database": "PubMed", "id": "23958494", "url": "https://pubmed.ncbi.nlm.nih.gov/23958494" }, { "database": "PubMed", "id": "24068326", "url": "https://pubmed.ncbi.nlm.nih.gov/24068326" }, { "database": "PubMed", "id": "24846082", "url": "https://pubmed.ncbi.nlm.nih.gov/24846082" }, { "database": "PubMed", "id": "25120613", "url": "https://pubmed.ncbi.nlm.nih.gov/25120613" }, { "database": "PubMed", "id": "25355439", "url": "https://pubmed.ncbi.nlm.nih.gov/25355439" }, { "database": "PubMed", "id": "25645159", "url": "https://pubmed.ncbi.nlm.nih.gov/25645159" }, { "database": "PubMed", "id": "25799226", "url": "https://pubmed.ncbi.nlm.nih.gov/25799226" }, { "database": "PubMed", "id": "26604643", "url": "https://pubmed.ncbi.nlm.nih.gov/26604643" }, { "database": "PubMed", "id": "26698173", "url": "https://pubmed.ncbi.nlm.nih.gov/26698173" }, { "database": "PubMed", "id": "26704265", "url": "https://pubmed.ncbi.nlm.nih.gov/26704265" }, { "database": "PubMed", "id": "26899161", "url": "https://pubmed.ncbi.nlm.nih.gov/26899161" }, { "database": "PubMed", "id": "26983645", "url": "https://pubmed.ncbi.nlm.nih.gov/26983645" }, { "database": "PubMed", "id": "27222060", "url": "https://pubmed.ncbi.nlm.nih.gov/27222060" }, { "database": "PubMed", "id": "27506476", "url": "https://pubmed.ncbi.nlm.nih.gov/27506476" }, { "database": "PubMed", "id": "27544192", "url": "https://pubmed.ncbi.nlm.nih.gov/27544192" }, { "database": "PubMed", "id": "27686967", "url": "https://pubmed.ncbi.nlm.nih.gov/27686967" }, { "database": "PubMed", "id": "27936435", "url": "https://pubmed.ncbi.nlm.nih.gov/27936435" }, { "database": "PubMed", "id": "28161417", "url": "https://pubmed.ncbi.nlm.nih.gov/28161417" }, { "database": "PubMed", "id": "28656239", "url": "https://pubmed.ncbi.nlm.nih.gov/28656239" }, { "database": "PubMed", "id": "28731188", "url": "https://pubmed.ncbi.nlm.nih.gov/28731188" }, { "database": "PubMed", "id": "28790390", "url": "https://pubmed.ncbi.nlm.nih.gov/28790390" }, { "database": "PubMed", "id": "28934129", "url": "https://pubmed.ncbi.nlm.nih.gov/28934129" }, { "database": "PubMed", "id": "29177868", "url": "https://pubmed.ncbi.nlm.nih.gov/29177868" }, { "database": "PubMed", "id": "29311680", "url": "https://pubmed.ncbi.nlm.nih.gov/29311680" }, { "database": "PubMed", "id": "29393871", "url": "https://pubmed.ncbi.nlm.nih.gov/29393871" }, { "database": "PubMed", "id": "29432553", "url": "https://pubmed.ncbi.nlm.nih.gov/29432553" }, { "database": "PubMed", "id": "29698741", "url": "https://pubmed.ncbi.nlm.nih.gov/29698741" }, { "database": "PubMed", "id": "29738527", "url": "https://pubmed.ncbi.nlm.nih.gov/29738527" }, { "database": "PubMed", "id": "30240640", "url": "https://pubmed.ncbi.nlm.nih.gov/30240640" }, { "database": "PubMed", "id": "30374127", "url": "https://pubmed.ncbi.nlm.nih.gov/30374127" }, { "database": "PubMed", "id": "30572687", "url": "https://pubmed.ncbi.nlm.nih.gov/30572687" }, { "database": "PubMed", "id": "31137828", "url": "https://pubmed.ncbi.nlm.nih.gov/31137828" }, { "database": "PubMed", "id": "31311314", "url": "https://pubmed.ncbi.nlm.nih.gov/31311314" }, { "database": "PubMed", "id": "31396538", "url": "https://pubmed.ncbi.nlm.nih.gov/31396538" }, { "database": "PubMed", "id": "32875583", "url": "https://pubmed.ncbi.nlm.nih.gov/32875583" }, { "database": "PubMed", "id": "33723215", "url": "https://pubmed.ncbi.nlm.nih.gov/33723215" }, { "database": "PubMed", "id": "35656886", "url": "https://pubmed.ncbi.nlm.nih.gov/35656886" }, { "database": "PubMed", "id": "18498745", "url": "https://pubmed.ncbi.nlm.nih.gov/18498745" } ], "site_lbl": "Ser307", "uniprot_canonical_ac": "P35568-1" } ], "record_id": "pubmed.16099428", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Overactivation of S6 kinase 1 as a cause of human insulin resistance during increased amino acid availability.", "journal": "Diabetes", "date": "2005", "authors": "Tremblay F, Krebs M, Dombrowski L, Brehm A, Bernroider E, Roth E, Nowotny P, Waldhausl W, Marette A, Roden M", "reference": { "type": "PubMed", "id": "16123357", "url": "https://pubmed.ncbi.nlm.nih.gov/16123357" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 312, "end_pos": 312, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by IKKB, MAPK8 and RPS6KB1", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "12351658", "url": "https://pubmed.ncbi.nlm.nih.gov/12351658" }, { "database": "PubMed", "id": "12510059", "url": "https://pubmed.ncbi.nlm.nih.gov/12510059" }, { "database": "PubMed", "id": "14769130", "url": "https://pubmed.ncbi.nlm.nih.gov/14769130" }, { "database": "PubMed", "id": "15044323", "url": "https://pubmed.ncbi.nlm.nih.gov/15044323" }, { "database": "PubMed", "id": "15613682", "url": "https://pubmed.ncbi.nlm.nih.gov/15613682" }, { "database": "PubMed", "id": "15713122", "url": "https://pubmed.ncbi.nlm.nih.gov/15713122" }, { "database": "PubMed", "id": "15952059", "url": "https://pubmed.ncbi.nlm.nih.gov/15952059" }, { "database": "PubMed", "id": "16123357", "url": "https://pubmed.ncbi.nlm.nih.gov/16123357" }, { "database": "PubMed", "id": "16284649", "url": "https://pubmed.ncbi.nlm.nih.gov/16284649" }, { "database": "PubMed", "id": "16505239", "url": "https://pubmed.ncbi.nlm.nih.gov/16505239" }, { "database": "PubMed", "id": "16505244", "url": "https://pubmed.ncbi.nlm.nih.gov/16505244" }, { "database": "PubMed", "id": "16516141", "url": "https://pubmed.ncbi.nlm.nih.gov/16516141" }, { "database": "PubMed", "id": "16960890", "url": "https://pubmed.ncbi.nlm.nih.gov/16960890" }, { "database": "PubMed", "id": "17204522", "url": "https://pubmed.ncbi.nlm.nih.gov/17204522" }, { "database": "PubMed", "id": "17242212", "url": "https://pubmed.ncbi.nlm.nih.gov/17242212" }, { "database": "PubMed", "id": "17360977", "url": "https://pubmed.ncbi.nlm.nih.gov/17360977" }, { "database": "PubMed", "id": "17647275", "url": "https://pubmed.ncbi.nlm.nih.gov/17647275" }, { "database": "PubMed", "id": "18160431", "url": "https://pubmed.ncbi.nlm.nih.gov/18160431" }, { "database": "PubMed", "id": "19501568", "url": "https://pubmed.ncbi.nlm.nih.gov/19501568" }, { "database": "PubMed", "id": "19567513", "url": "https://pubmed.ncbi.nlm.nih.gov/19567513" }, { "database": "PubMed", "id": "19593406", "url": "https://pubmed.ncbi.nlm.nih.gov/19593406" }, { "database": "PubMed", "id": "20393162", "url": "https://pubmed.ncbi.nlm.nih.gov/20393162" }, { "database": "PubMed", "id": "20685959", "url": "https://pubmed.ncbi.nlm.nih.gov/20685959" }, { "database": "PubMed", "id": "20863384", "url": "https://pubmed.ncbi.nlm.nih.gov/20863384" }, { "database": "PubMed", "id": "21040800", "url": "https://pubmed.ncbi.nlm.nih.gov/21040800" }, { "database": "PubMed", "id": "21252690", "url": "https://pubmed.ncbi.nlm.nih.gov/21252690" }, { "database": "PubMed", "id": "21589939", "url": "https://pubmed.ncbi.nlm.nih.gov/21589939" }, { "database": "PubMed", "id": "21852229", "url": "https://pubmed.ncbi.nlm.nih.gov/21852229" }, { "database": "PubMed", "id": "21937042", "url": "https://pubmed.ncbi.nlm.nih.gov/21937042" }, { "database": "PubMed", "id": "22348058", "url": "https://pubmed.ncbi.nlm.nih.gov/22348058" }, { "database": "PubMed", "id": "22457223", "url": "https://pubmed.ncbi.nlm.nih.gov/22457223" }, { "database": "PubMed", "id": "22862962", "url": "https://pubmed.ncbi.nlm.nih.gov/22862962" }, { "database": "PubMed", "id": "25580119", "url": "https://pubmed.ncbi.nlm.nih.gov/25580119" }, { "database": "PubMed", "id": "27207509", "url": "https://pubmed.ncbi.nlm.nih.gov/27207509" }, { "database": "PubMed", "id": "27340831", "url": "https://pubmed.ncbi.nlm.nih.gov/27340831" }, { "database": "PubMed", "id": "32536688", "url": "https://pubmed.ncbi.nlm.nih.gov/32536688" }, { "database": "PubMed", "id": "33173197", "url": "https://pubmed.ncbi.nlm.nih.gov/33173197" }, { "database": "PubMed", "id": "35833836", "url": "https://pubmed.ncbi.nlm.nih.gov/35833836" }, { "database": "PubMed", "id": "18498745", "url": "https://pubmed.ncbi.nlm.nih.gov/18498745" } ], "site_lbl": "Ser312", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 636, "end_pos": 636, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by RPS6KB1", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "16131083", "url": "https://pubmed.ncbi.nlm.nih.gov/16131083" }, { "database": "PubMed", "id": "19651622", "url": "https://pubmed.ncbi.nlm.nih.gov/19651622" }, { "database": "PubMed", "id": "16354680", "url": "https://pubmed.ncbi.nlm.nih.gov/16354680" }, { "database": "PubMed", "id": "11287630", "url": "https://pubmed.ncbi.nlm.nih.gov/11287630" }, { "database": "PubMed", "id": "12765939", "url": "https://pubmed.ncbi.nlm.nih.gov/12765939" }, { "database": "PubMed", "id": "14769130", "url": "https://pubmed.ncbi.nlm.nih.gov/14769130" }, { "database": "PubMed", "id": "15576463", "url": "https://pubmed.ncbi.nlm.nih.gov/15576463" }, { "database": "PubMed", "id": "16123357", "url": "https://pubmed.ncbi.nlm.nih.gov/16123357" }, { "database": "PubMed", "id": "16284649", "url": "https://pubmed.ncbi.nlm.nih.gov/16284649" }, { "database": "PubMed", "id": "17360977", "url": "https://pubmed.ncbi.nlm.nih.gov/17360977" }, { "database": "PubMed", "id": "17640984", "url": "https://pubmed.ncbi.nlm.nih.gov/17640984" }, { "database": "PubMed", "id": "18597775", "url": "https://pubmed.ncbi.nlm.nih.gov/18597775" }, { "database": "PubMed", "id": "18952604", "url": "https://pubmed.ncbi.nlm.nih.gov/18952604" }, { "database": "PubMed", "id": "19561084", "url": "https://pubmed.ncbi.nlm.nih.gov/19561084" }, { "database": "PubMed", "id": "19581421", "url": "https://pubmed.ncbi.nlm.nih.gov/19581421" }, { "database": "PubMed", "id": "20203102", "url": "https://pubmed.ncbi.nlm.nih.gov/20203102" }, { "database": "PubMed", "id": "21478152", "url": "https://pubmed.ncbi.nlm.nih.gov/21478152" }, { "database": "PubMed", "id": "21829658", "url": "https://pubmed.ncbi.nlm.nih.gov/21829658" }, { "database": "PubMed", "id": "22348058", "url": "https://pubmed.ncbi.nlm.nih.gov/22348058" }, { "database": "PubMed", "id": "22966072", "url": "https://pubmed.ncbi.nlm.nih.gov/22966072" }, { "database": "PubMed", "id": "23512499", "url": "https://pubmed.ncbi.nlm.nih.gov/23512499" }, { "database": "PubMed", "id": "25667991", "url": "https://pubmed.ncbi.nlm.nih.gov/25667991" }, { "database": "PubMed", "id": "25799226", "url": "https://pubmed.ncbi.nlm.nih.gov/25799226" }, { "database": "PubMed", "id": "25813876", "url": "https://pubmed.ncbi.nlm.nih.gov/25813876" }, { "database": "PubMed", "id": "26077338", "url": "https://pubmed.ncbi.nlm.nih.gov/26077338" }, { "database": "PubMed", "id": "27434075", "url": "https://pubmed.ncbi.nlm.nih.gov/27434075" }, { "database": "PubMed", "id": "28652303", "url": "https://pubmed.ncbi.nlm.nih.gov/28652303" }, { "database": "PubMed", "id": "28934129", "url": "https://pubmed.ncbi.nlm.nih.gov/28934129" }, { "database": "PubMed", "id": "30381640", "url": "https://pubmed.ncbi.nlm.nih.gov/30381640" }, { "database": "PubMed", "id": "36111162", "url": "https://pubmed.ncbi.nlm.nih.gov/36111162" }, { "database": "PubMed", "id": "18498745", "url": "https://pubmed.ncbi.nlm.nih.gov/18498745" }, { "database": "PubMed", "id": "17081983", "url": "https://pubmed.ncbi.nlm.nih.gov/17081983" } ], "site_lbl": "Ser636", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 639, "end_pos": 639, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "16354680", "url": "https://pubmed.ncbi.nlm.nih.gov/16354680" }, { "database": "PubMed", "id": "11287630", "url": "https://pubmed.ncbi.nlm.nih.gov/11287630" }, { "database": "PubMed", "id": "14769130", "url": "https://pubmed.ncbi.nlm.nih.gov/14769130" }, { "database": "PubMed", "id": "15576463", "url": "https://pubmed.ncbi.nlm.nih.gov/15576463" }, { "database": "PubMed", "id": "16123357", "url": "https://pubmed.ncbi.nlm.nih.gov/16123357" }, { "database": "PubMed", "id": "19561084", "url": "https://pubmed.ncbi.nlm.nih.gov/19561084" }, { "database": "PubMed", "id": "20203102", "url": "https://pubmed.ncbi.nlm.nih.gov/20203102" }, { "database": "PubMed", "id": "21478152", "url": "https://pubmed.ncbi.nlm.nih.gov/21478152" }, { "database": "PubMed", "id": "21829658", "url": "https://pubmed.ncbi.nlm.nih.gov/21829658" }, { "database": "PubMed", "id": "23512499", "url": "https://pubmed.ncbi.nlm.nih.gov/23512499" }, { "database": "PubMed", "id": "25667991", "url": "https://pubmed.ncbi.nlm.nih.gov/25667991" }, { "database": "PubMed", "id": "25799226", "url": "https://pubmed.ncbi.nlm.nih.gov/25799226" }, { "database": "PubMed", "id": "30381640", "url": "https://pubmed.ncbi.nlm.nih.gov/30381640" } ], "site_lbl": "Ser639", "uniprot_canonical_ac": "P35568-1" } ], "record_id": "pubmed.16123357", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Identification of phosphorylation sites in insulin receptor substrate-1 by hypothesis-driven high-performance liquid chromatography-electrospray ionization tandem mass spectrometry.", "journal": "Analytical chemistry", "date": "2005", "authors": "Yi Z, Luo M, Carroll CA, Weintraub ST, Mandarino LJ", "reference": { "type": "PubMed", "id": "16131083", "url": "https://pubmed.ncbi.nlm.nih.gov/16131083" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 1223, "end_pos": 1223, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "16131083", "url": "https://pubmed.ncbi.nlm.nih.gov/16131083" }, { "database": "PubMed", "id": "16020478", "url": "https://pubmed.ncbi.nlm.nih.gov/16020478" }, { "database": "PubMed", "id": "17360977", "url": "https://pubmed.ncbi.nlm.nih.gov/17360977" } ], "site_lbl": "Ser1223", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 574, "end_pos": 574, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "16131083", "url": "https://pubmed.ncbi.nlm.nih.gov/16131083" }, { "database": "PubMed", "id": "14583092", "url": "https://pubmed.ncbi.nlm.nih.gov/14583092" } ], "site_lbl": "Ser574", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 616, "end_pos": 616, "kinase_uniprot_canonical_ac": "P28482-1", "kinase_gene_name": "MAPK1", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "16131083", "url": "https://pubmed.ncbi.nlm.nih.gov/16131083" }, { "database": "PubMed", "id": "9395471", "url": "https://pubmed.ncbi.nlm.nih.gov/9395471" }, { "database": "PubMed", "id": "15001544", "url": "https://pubmed.ncbi.nlm.nih.gov/15001544" } ], "site_lbl": "Ser616", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 629, "end_pos": 629, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "PubMed", "id": "24275569", "url": "https://pubmed.ncbi.nlm.nih.gov/24275569" }, { "database": "PubMed", "id": "17081983", "url": "https://pubmed.ncbi.nlm.nih.gov/17081983" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "16131083", "url": "https://pubmed.ncbi.nlm.nih.gov/16131083" }, { "database": "PubMed", "id": "19651622", "url": "https://pubmed.ncbi.nlm.nih.gov/19651622" }, { "database": "PubMed", "id": "17640984", "url": "https://pubmed.ncbi.nlm.nih.gov/17640984" } ], "site_lbl": "Ser629", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 636, "end_pos": 636, "kinase_uniprot_canonical_ac": "P28482-1", "kinase_gene_name": "MAPK1", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "16131083", "url": "https://pubmed.ncbi.nlm.nih.gov/16131083" }, { "database": "PubMed", "id": "19651622", "url": "https://pubmed.ncbi.nlm.nih.gov/19651622" }, { "database": "PubMed", "id": "17640984", "url": "https://pubmed.ncbi.nlm.nih.gov/17640984" }, { "database": "PubMed", "id": "12510059", "url": "https://pubmed.ncbi.nlm.nih.gov/12510059" } ], "site_lbl": "Ser636", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 636, "end_pos": 636, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by RPS6KB1", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "16131083", "url": "https://pubmed.ncbi.nlm.nih.gov/16131083" }, { "database": "PubMed", "id": "19651622", "url": "https://pubmed.ncbi.nlm.nih.gov/19651622" }, { "database": "PubMed", "id": "16354680", "url": "https://pubmed.ncbi.nlm.nih.gov/16354680" }, { "database": "PubMed", "id": "11287630", "url": "https://pubmed.ncbi.nlm.nih.gov/11287630" }, { "database": "PubMed", "id": "12765939", "url": "https://pubmed.ncbi.nlm.nih.gov/12765939" }, { "database": "PubMed", "id": "14769130", "url": "https://pubmed.ncbi.nlm.nih.gov/14769130" }, { "database": "PubMed", "id": "15576463", "url": "https://pubmed.ncbi.nlm.nih.gov/15576463" }, { "database": "PubMed", "id": "16123357", "url": "https://pubmed.ncbi.nlm.nih.gov/16123357" }, { "database": "PubMed", "id": "16284649", "url": "https://pubmed.ncbi.nlm.nih.gov/16284649" }, { "database": "PubMed", "id": "17360977", "url": "https://pubmed.ncbi.nlm.nih.gov/17360977" }, { "database": "PubMed", "id": "17640984", "url": "https://pubmed.ncbi.nlm.nih.gov/17640984" }, { "database": "PubMed", "id": "18597775", "url": "https://pubmed.ncbi.nlm.nih.gov/18597775" }, { "database": "PubMed", "id": "18952604", "url": "https://pubmed.ncbi.nlm.nih.gov/18952604" }, { "database": "PubMed", "id": "19561084", "url": "https://pubmed.ncbi.nlm.nih.gov/19561084" }, { "database": "PubMed", "id": "19581421", "url": "https://pubmed.ncbi.nlm.nih.gov/19581421" }, { "database": "PubMed", "id": "20203102", "url": "https://pubmed.ncbi.nlm.nih.gov/20203102" }, { "database": "PubMed", "id": "21478152", "url": "https://pubmed.ncbi.nlm.nih.gov/21478152" }, { "database": "PubMed", "id": "21829658", "url": "https://pubmed.ncbi.nlm.nih.gov/21829658" }, { "database": "PubMed", "id": "22348058", "url": "https://pubmed.ncbi.nlm.nih.gov/22348058" }, { "database": "PubMed", "id": "22966072", "url": "https://pubmed.ncbi.nlm.nih.gov/22966072" }, { "database": "PubMed", "id": "23512499", "url": "https://pubmed.ncbi.nlm.nih.gov/23512499" }, { "database": "PubMed", "id": "25667991", "url": "https://pubmed.ncbi.nlm.nih.gov/25667991" }, { "database": "PubMed", "id": "25799226", "url": "https://pubmed.ncbi.nlm.nih.gov/25799226" }, { "database": "PubMed", "id": "25813876", "url": "https://pubmed.ncbi.nlm.nih.gov/25813876" }, { "database": "PubMed", "id": "26077338", "url": "https://pubmed.ncbi.nlm.nih.gov/26077338" }, { "database": "PubMed", "id": "27434075", "url": "https://pubmed.ncbi.nlm.nih.gov/27434075" }, { "database": "PubMed", "id": "28652303", "url": "https://pubmed.ncbi.nlm.nih.gov/28652303" }, { "database": "PubMed", "id": "28934129", "url": "https://pubmed.ncbi.nlm.nih.gov/28934129" }, { "database": "PubMed", "id": "30381640", "url": "https://pubmed.ncbi.nlm.nih.gov/30381640" }, { "database": "PubMed", "id": "36111162", "url": "https://pubmed.ncbi.nlm.nih.gov/36111162" }, { "database": "PubMed", "id": "18498745", "url": "https://pubmed.ncbi.nlm.nih.gov/18498745" }, { "database": "PubMed", "id": "17081983", "url": "https://pubmed.ncbi.nlm.nih.gov/17081983" } ], "site_lbl": "Ser636", "uniprot_canonical_ac": "P35568-1" } ], "record_id": "pubmed.16131083", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 6 }, { "field": "total_sites", "count": 5 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Exercise does not alter subcellular localization, but increases phosphorylation of insulin-signaling proteins in human skeletal muscle.", "journal": "American journal of physiology. Endocrinology and metabolism", "date": "2006", "authors": "Wilson C, Hargreaves M, Howlett KF", "reference": { "type": "PubMed", "id": "16188907", "url": "https://pubmed.ncbi.nlm.nih.gov/16188907" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 612, "end_pos": 612, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by INSR", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "12220227", "url": "https://pubmed.ncbi.nlm.nih.gov/12220227" }, { "database": "IntAct", "id": "P35568", "url": "https://www.ebi.ac.uk/intact/interactors/id:P35568*" }, { "database": "PubMed", "id": "16230374", "url": "https://pubmed.ncbi.nlm.nih.gov/16230374" }, { "database": "PubMed", "id": "11416002", "url": "https://pubmed.ncbi.nlm.nih.gov/11416002" }, { "database": "PRO", "id": "P35568", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=P35568" }, { "database": "PubMed", "id": "15044323", "url": "https://pubmed.ncbi.nlm.nih.gov/15044323" }, { "database": "PubMed", "id": "16188907", "url": "https://pubmed.ncbi.nlm.nih.gov/16188907" }, { "database": "PubMed", "id": "17242212", "url": "https://pubmed.ncbi.nlm.nih.gov/17242212" }, { "database": "PubMed", "id": "17902048", "url": "https://pubmed.ncbi.nlm.nih.gov/17902048" }, { "database": "PubMed", "id": "19762915", "url": "https://pubmed.ncbi.nlm.nih.gov/19762915" }, { "database": "PubMed", "id": "20150288", "url": "https://pubmed.ncbi.nlm.nih.gov/20150288" }, { "database": "PubMed", "id": "21829658", "url": "https://pubmed.ncbi.nlm.nih.gov/21829658" }, { "database": "PubMed", "id": "21939528", "url": "https://pubmed.ncbi.nlm.nih.gov/21939528" }, { "database": "PubMed", "id": "23360399", "url": "https://pubmed.ncbi.nlm.nih.gov/23360399" }, { "database": "PubMed", "id": "23460259", "url": "https://pubmed.ncbi.nlm.nih.gov/23460259" }, { "database": "PubMed", "id": "23688189", "url": "https://pubmed.ncbi.nlm.nih.gov/23688189" }, { "database": "PubMed", "id": "25302072", "url": "https://pubmed.ncbi.nlm.nih.gov/25302072" }, { "database": "PubMed", "id": "25886138", "url": "https://pubmed.ncbi.nlm.nih.gov/25886138" }, { "database": "PubMed", "id": "26297026", "url": "https://pubmed.ncbi.nlm.nih.gov/26297026" }, { "database": "PubMed", "id": "26874193", "url": "https://pubmed.ncbi.nlm.nih.gov/26874193" }, { "database": "PubMed", "id": "28161417", "url": "https://pubmed.ncbi.nlm.nih.gov/28161417" }, { "database": "PubMed", "id": "28345670", "url": "https://pubmed.ncbi.nlm.nih.gov/28345670" }, { "database": "PubMed", "id": "28414818", "url": "https://pubmed.ncbi.nlm.nih.gov/28414818" }, { "database": "PubMed", "id": "28934129", "url": "https://pubmed.ncbi.nlm.nih.gov/28934129" }, { "database": "PubMed", "id": "28955049", "url": "https://pubmed.ncbi.nlm.nih.gov/28955049" }, { "database": "PubMed", "id": "29259227", "url": "https://pubmed.ncbi.nlm.nih.gov/29259227" }, { "database": "PubMed", "id": "29486856", "url": "https://pubmed.ncbi.nlm.nih.gov/29486856" }, { "database": "PubMed", "id": "30092354", "url": "https://pubmed.ncbi.nlm.nih.gov/30092354" }, { "database": "PubMed", "id": "23401856", "url": "https://pubmed.ncbi.nlm.nih.gov/23401856" } ], "site_lbl": "Tyr612", "uniprot_canonical_ac": "P35568-1" } ], "record_id": "pubmed.16188907", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Insulin receptor substrate is a mediator of phosphoinositide 3-kinase activation in quiescent pancreatic cancer cells.", "journal": "Cancer research", "date": "2005-10-15", "authors": "Asano Takayuki, Yao Yixin, Shin Sonyo, McCubrey James, Abbruzzese James L, Reddy Shrikanth A G", "reference": { "type": "PubMed", "id": "16230374", "url": "https://pubmed.ncbi.nlm.nih.gov/16230374" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 612, "end_pos": 612, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by INSR", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "12220227", "url": "https://pubmed.ncbi.nlm.nih.gov/12220227" }, { "database": "IntAct", "id": "P35568", "url": "https://www.ebi.ac.uk/intact/interactors/id:P35568*" }, { "database": "PubMed", "id": "16230374", "url": "https://pubmed.ncbi.nlm.nih.gov/16230374" }, { "database": "PubMed", "id": "11416002", "url": "https://pubmed.ncbi.nlm.nih.gov/11416002" }, { "database": "PRO", "id": "P35568", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=P35568" }, { "database": "PubMed", "id": "15044323", "url": "https://pubmed.ncbi.nlm.nih.gov/15044323" }, { "database": "PubMed", "id": "16188907", "url": "https://pubmed.ncbi.nlm.nih.gov/16188907" }, { "database": "PubMed", "id": "17242212", "url": "https://pubmed.ncbi.nlm.nih.gov/17242212" }, { "database": "PubMed", "id": "17902048", "url": "https://pubmed.ncbi.nlm.nih.gov/17902048" }, { "database": "PubMed", "id": "19762915", "url": "https://pubmed.ncbi.nlm.nih.gov/19762915" }, { "database": "PubMed", "id": "20150288", "url": "https://pubmed.ncbi.nlm.nih.gov/20150288" }, { "database": "PubMed", "id": "21829658", "url": "https://pubmed.ncbi.nlm.nih.gov/21829658" }, { "database": "PubMed", "id": "21939528", "url": "https://pubmed.ncbi.nlm.nih.gov/21939528" }, { "database": "PubMed", "id": "23360399", "url": "https://pubmed.ncbi.nlm.nih.gov/23360399" }, { "database": "PubMed", "id": "23460259", "url": "https://pubmed.ncbi.nlm.nih.gov/23460259" }, { "database": "PubMed", "id": "23688189", "url": "https://pubmed.ncbi.nlm.nih.gov/23688189" }, { "database": "PubMed", "id": "25302072", "url": "https://pubmed.ncbi.nlm.nih.gov/25302072" }, { "database": "PubMed", "id": "25886138", "url": "https://pubmed.ncbi.nlm.nih.gov/25886138" }, { "database": "PubMed", "id": "26297026", "url": "https://pubmed.ncbi.nlm.nih.gov/26297026" }, { "database": "PubMed", "id": "26874193", "url": "https://pubmed.ncbi.nlm.nih.gov/26874193" }, { "database": "PubMed", "id": "28161417", "url": "https://pubmed.ncbi.nlm.nih.gov/28161417" }, { "database": "PubMed", "id": "28345670", "url": "https://pubmed.ncbi.nlm.nih.gov/28345670" }, { "database": "PubMed", "id": "28414818", "url": "https://pubmed.ncbi.nlm.nih.gov/28414818" }, { "database": "PubMed", "id": "28934129", "url": "https://pubmed.ncbi.nlm.nih.gov/28934129" }, { "database": "PubMed", "id": "28955049", "url": "https://pubmed.ncbi.nlm.nih.gov/28955049" }, { "database": "PubMed", "id": "29259227", "url": "https://pubmed.ncbi.nlm.nih.gov/29259227" }, { "database": "PubMed", "id": "29486856", "url": "https://pubmed.ncbi.nlm.nih.gov/29486856" }, { "database": "PubMed", "id": "30092354", "url": "https://pubmed.ncbi.nlm.nih.gov/30092354" }, { "database": "PubMed", "id": "23401856", "url": "https://pubmed.ncbi.nlm.nih.gov/23401856" } ], "site_lbl": "Tyr612", "uniprot_canonical_ac": "P35568-1" } ], "record_id": "pubmed.16230374", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Altered subcellular distribution of estrogen receptor alpha is implicated in estradiol-induced dual regulation of insulin signaling in 3T3-L1 adipocytes.", "journal": "Endocrinology", "date": "2006", "authors": "Nagira K, Sasaoka T, Wada T, Fukui K, Ikubo M, Hori S, Tsuneki H, Saito S, Kobayashi M", "reference": { "type": "PubMed", "id": "16269459", "url": "https://pubmed.ncbi.nlm.nih.gov/16269459" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 307, "end_pos": 307, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by RPS6KB1", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "11160134", "url": "https://pubmed.ncbi.nlm.nih.gov/11160134" }, { "database": "PubMed", "id": "11606564", "url": "https://pubmed.ncbi.nlm.nih.gov/11606564" }, { "database": "PubMed", "id": "12409308", "url": "https://pubmed.ncbi.nlm.nih.gov/12409308" }, { "database": "PubMed", "id": "12714600", "url": "https://pubmed.ncbi.nlm.nih.gov/12714600" }, { "database": "PubMed", "id": "12730242", "url": "https://pubmed.ncbi.nlm.nih.gov/12730242" }, { "database": "PubMed", "id": "14556646", "url": "https://pubmed.ncbi.nlm.nih.gov/14556646" }, { "database": "PubMed", "id": "14583092", "url": "https://pubmed.ncbi.nlm.nih.gov/14583092" }, { "database": "PubMed", "id": "14641015", "url": "https://pubmed.ncbi.nlm.nih.gov/14641015" }, { "database": "PubMed", "id": "14697666", "url": "https://pubmed.ncbi.nlm.nih.gov/14697666" }, { "database": "PubMed", "id": "15020250", "url": "https://pubmed.ncbi.nlm.nih.gov/15020250" }, { "database": "PubMed", "id": "15153564", "url": "https://pubmed.ncbi.nlm.nih.gov/15153564" }, { "database": "PubMed", "id": "15582605", "url": "https://pubmed.ncbi.nlm.nih.gov/15582605" }, { "database": "PubMed", "id": "15802620", "url": "https://pubmed.ncbi.nlm.nih.gov/15802620" }, { "database": "PubMed", "id": "16046301", "url": "https://pubmed.ncbi.nlm.nih.gov/16046301" }, { "database": "PubMed", "id": "16055440", "url": "https://pubmed.ncbi.nlm.nih.gov/16055440" }, { "database": "PubMed", "id": "16099428", "url": "https://pubmed.ncbi.nlm.nih.gov/16099428" }, { "database": "PubMed", "id": "16210322", "url": "https://pubmed.ncbi.nlm.nih.gov/16210322" }, { "database": "PubMed", "id": "16269459", "url": "https://pubmed.ncbi.nlm.nih.gov/16269459" }, { "database": "PubMed", "id": "16516141", "url": "https://pubmed.ncbi.nlm.nih.gov/16516141" }, { "database": "PubMed", "id": "16754954", "url": "https://pubmed.ncbi.nlm.nih.gov/16754954" }, { "database": "PubMed", "id": "16839860", "url": "https://pubmed.ncbi.nlm.nih.gov/16839860" }, { "database": "PubMed", "id": "17077083", "url": "https://pubmed.ncbi.nlm.nih.gov/17077083" }, { "database": "PubMed", "id": "17095576", "url": "https://pubmed.ncbi.nlm.nih.gov/17095576" }, { "database": "PubMed", "id": "17276034", "url": "https://pubmed.ncbi.nlm.nih.gov/17276034" }, { "database": "PubMed", "id": "17481767", "url": "https://pubmed.ncbi.nlm.nih.gov/17481767" }, { "database": "PubMed", "id": "17575262", "url": "https://pubmed.ncbi.nlm.nih.gov/17575262" }, { "database": "PubMed", "id": "18187553", "url": "https://pubmed.ncbi.nlm.nih.gov/18187553" }, { "database": "PubMed", "id": "18372392", "url": "https://pubmed.ncbi.nlm.nih.gov/18372392" }, { "database": "PubMed", "id": "18380932", "url": "https://pubmed.ncbi.nlm.nih.gov/18380932" }, { "database": "PubMed", "id": "18496818", "url": "https://pubmed.ncbi.nlm.nih.gov/18496818" }, { "database": "PubMed", "id": "18952604", "url": "https://pubmed.ncbi.nlm.nih.gov/18952604" }, { "database": "PubMed", "id": "19095745", "url": "https://pubmed.ncbi.nlm.nih.gov/19095745" }, { "database": "PubMed", "id": "19524129", "url": "https://pubmed.ncbi.nlm.nih.gov/19524129" }, { "database": "PubMed", "id": "19897715", "url": "https://pubmed.ncbi.nlm.nih.gov/19897715" }, { "database": "PubMed", "id": "20351777", "url": "https://pubmed.ncbi.nlm.nih.gov/20351777" }, { "database": "PubMed", "id": "20382011", "url": "https://pubmed.ncbi.nlm.nih.gov/20382011" }, { "database": "PubMed", "id": "20384568", "url": "https://pubmed.ncbi.nlm.nih.gov/20384568" }, { "database": "PubMed", "id": "20541543", "url": "https://pubmed.ncbi.nlm.nih.gov/20541543" }, { "database": "PubMed", "id": "20587749", "url": "https://pubmed.ncbi.nlm.nih.gov/20587749" }, { "database": "PubMed", "id": "20594161", "url": "https://pubmed.ncbi.nlm.nih.gov/20594161" }, { "database": "PubMed", "id": "20594757", "url": "https://pubmed.ncbi.nlm.nih.gov/20594757" }, { "database": "PubMed", "id": "20702573", "url": "https://pubmed.ncbi.nlm.nih.gov/20702573" }, { "database": "PubMed", "id": "21119656", "url": "https://pubmed.ncbi.nlm.nih.gov/21119656" }, { "database": "PubMed", "id": "21478152", "url": "https://pubmed.ncbi.nlm.nih.gov/21478152" }, { "database": "PubMed", "id": "21505982", "url": "https://pubmed.ncbi.nlm.nih.gov/21505982" }, { "database": "PubMed", "id": "21786209", "url": "https://pubmed.ncbi.nlm.nih.gov/21786209" }, { "database": "PubMed", "id": "21852229", "url": "https://pubmed.ncbi.nlm.nih.gov/21852229" }, { "database": "PubMed", "id": "21900690", "url": "https://pubmed.ncbi.nlm.nih.gov/21900690" }, { "database": "PubMed", "id": "22046423", "url": "https://pubmed.ncbi.nlm.nih.gov/22046423" }, { "database": "PubMed", "id": "22227580", "url": "https://pubmed.ncbi.nlm.nih.gov/22227580" }, { "database": "PubMed", "id": "22266116", "url": "https://pubmed.ncbi.nlm.nih.gov/22266116" }, { "database": "PubMed", "id": "22328823", "url": "https://pubmed.ncbi.nlm.nih.gov/22328823" }, { "database": "PubMed", "id": "22348058", "url": "https://pubmed.ncbi.nlm.nih.gov/22348058" }, { "database": "PubMed", "id": "22491740", "url": "https://pubmed.ncbi.nlm.nih.gov/22491740" }, { "database": "PubMed", "id": "22728372", "url": "https://pubmed.ncbi.nlm.nih.gov/22728372" }, { "database": "PubMed", "id": "22766331", "url": "https://pubmed.ncbi.nlm.nih.gov/22766331" }, { "database": "PubMed", "id": "23095254", "url": "https://pubmed.ncbi.nlm.nih.gov/23095254" }, { "database": "PubMed", "id": "23174405", "url": "https://pubmed.ncbi.nlm.nih.gov/23174405" }, { "database": "PubMed", "id": "23182460", "url": "https://pubmed.ncbi.nlm.nih.gov/23182460" }, { "database": "PubMed", "id": "23481042", "url": "https://pubmed.ncbi.nlm.nih.gov/23481042" }, { "database": "PubMed", "id": "23566306", "url": "https://pubmed.ncbi.nlm.nih.gov/23566306" }, { "database": "PubMed", "id": "23592917", "url": "https://pubmed.ncbi.nlm.nih.gov/23592917" }, { "database": "PubMed", "id": "23891856", "url": "https://pubmed.ncbi.nlm.nih.gov/23891856" }, { "database": "PubMed", "id": "23958494", "url": "https://pubmed.ncbi.nlm.nih.gov/23958494" }, { "database": "PubMed", "id": "24068326", "url": "https://pubmed.ncbi.nlm.nih.gov/24068326" }, { "database": "PubMed", "id": "24846082", "url": "https://pubmed.ncbi.nlm.nih.gov/24846082" }, { "database": "PubMed", "id": "25120613", "url": "https://pubmed.ncbi.nlm.nih.gov/25120613" }, { "database": "PubMed", "id": "25355439", "url": "https://pubmed.ncbi.nlm.nih.gov/25355439" }, { "database": "PubMed", "id": "25645159", "url": "https://pubmed.ncbi.nlm.nih.gov/25645159" }, { "database": "PubMed", "id": "25799226", "url": "https://pubmed.ncbi.nlm.nih.gov/25799226" }, { "database": "PubMed", "id": "26604643", "url": "https://pubmed.ncbi.nlm.nih.gov/26604643" }, { "database": "PubMed", "id": "26698173", "url": "https://pubmed.ncbi.nlm.nih.gov/26698173" }, { "database": "PubMed", "id": "26704265", "url": "https://pubmed.ncbi.nlm.nih.gov/26704265" }, { "database": "PubMed", "id": "26899161", "url": "https://pubmed.ncbi.nlm.nih.gov/26899161" }, { "database": "PubMed", "id": "26983645", "url": "https://pubmed.ncbi.nlm.nih.gov/26983645" }, { "database": "PubMed", "id": "27222060", "url": "https://pubmed.ncbi.nlm.nih.gov/27222060" }, { "database": "PubMed", "id": "27506476", "url": "https://pubmed.ncbi.nlm.nih.gov/27506476" }, { "database": "PubMed", "id": "27544192", "url": "https://pubmed.ncbi.nlm.nih.gov/27544192" }, { "database": "PubMed", "id": "27686967", "url": "https://pubmed.ncbi.nlm.nih.gov/27686967" }, { "database": "PubMed", "id": "27936435", "url": "https://pubmed.ncbi.nlm.nih.gov/27936435" }, { "database": "PubMed", "id": "28161417", "url": "https://pubmed.ncbi.nlm.nih.gov/28161417" }, { "database": "PubMed", "id": "28656239", "url": "https://pubmed.ncbi.nlm.nih.gov/28656239" }, { "database": "PubMed", "id": "28731188", "url": "https://pubmed.ncbi.nlm.nih.gov/28731188" }, { "database": "PubMed", "id": "28790390", "url": "https://pubmed.ncbi.nlm.nih.gov/28790390" }, { "database": "PubMed", "id": "28934129", "url": "https://pubmed.ncbi.nlm.nih.gov/28934129" }, { "database": "PubMed", "id": "29177868", "url": "https://pubmed.ncbi.nlm.nih.gov/29177868" }, { "database": "PubMed", "id": "29311680", "url": "https://pubmed.ncbi.nlm.nih.gov/29311680" }, { "database": "PubMed", "id": "29393871", "url": "https://pubmed.ncbi.nlm.nih.gov/29393871" }, { "database": "PubMed", "id": "29432553", "url": "https://pubmed.ncbi.nlm.nih.gov/29432553" }, { "database": "PubMed", "id": "29698741", "url": "https://pubmed.ncbi.nlm.nih.gov/29698741" }, { "database": "PubMed", "id": "29738527", "url": "https://pubmed.ncbi.nlm.nih.gov/29738527" }, { "database": "PubMed", "id": "30240640", "url": "https://pubmed.ncbi.nlm.nih.gov/30240640" }, { "database": "PubMed", "id": "30374127", "url": "https://pubmed.ncbi.nlm.nih.gov/30374127" }, { "database": "PubMed", "id": "30572687", "url": "https://pubmed.ncbi.nlm.nih.gov/30572687" }, { "database": "PubMed", "id": "31137828", "url": "https://pubmed.ncbi.nlm.nih.gov/31137828" }, { "database": "PubMed", "id": "31311314", "url": "https://pubmed.ncbi.nlm.nih.gov/31311314" }, { "database": "PubMed", "id": "31396538", "url": "https://pubmed.ncbi.nlm.nih.gov/31396538" }, { "database": "PubMed", "id": "32875583", "url": "https://pubmed.ncbi.nlm.nih.gov/32875583" }, { "database": "PubMed", "id": "33723215", "url": "https://pubmed.ncbi.nlm.nih.gov/33723215" }, { "database": "PubMed", "id": "35656886", "url": "https://pubmed.ncbi.nlm.nih.gov/35656886" }, { "database": "PubMed", "id": "18498745", "url": "https://pubmed.ncbi.nlm.nih.gov/18498745" } ], "site_lbl": "Ser307", "uniprot_canonical_ac": "P35568-1" } ], "record_id": "pubmed.16269459", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Reduced mitochondrial density and increased IRS-1 serine phosphorylation in muscle of insulin-resistant offspring of type 2 diabetic parents.", "journal": "The Journal of clinical investigation", "date": "2005", "authors": "Morino K, Petersen KF, Dufour S, Befroy D, Frattini J, Shatzkes N, Neschen S, White MF, Bilz S, Sono S, Pypaert M, Shulman GI", "reference": { "type": "PubMed", "id": "16284649", "url": "https://pubmed.ncbi.nlm.nih.gov/16284649" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 312, "end_pos": 312, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by IKKB, MAPK8 and RPS6KB1", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "12351658", "url": "https://pubmed.ncbi.nlm.nih.gov/12351658" }, { "database": "PubMed", "id": "12510059", "url": "https://pubmed.ncbi.nlm.nih.gov/12510059" }, { "database": "PubMed", "id": "14769130", "url": "https://pubmed.ncbi.nlm.nih.gov/14769130" }, { "database": "PubMed", "id": "15044323", "url": "https://pubmed.ncbi.nlm.nih.gov/15044323" }, { "database": "PubMed", "id": "15613682", "url": "https://pubmed.ncbi.nlm.nih.gov/15613682" }, { "database": "PubMed", "id": "15713122", "url": "https://pubmed.ncbi.nlm.nih.gov/15713122" }, { "database": "PubMed", "id": "15952059", "url": "https://pubmed.ncbi.nlm.nih.gov/15952059" }, { "database": "PubMed", "id": "16123357", "url": "https://pubmed.ncbi.nlm.nih.gov/16123357" }, { "database": "PubMed", "id": "16284649", "url": "https://pubmed.ncbi.nlm.nih.gov/16284649" }, { "database": "PubMed", "id": "16505239", "url": "https://pubmed.ncbi.nlm.nih.gov/16505239" }, { "database": "PubMed", "id": "16505244", "url": "https://pubmed.ncbi.nlm.nih.gov/16505244" }, { "database": "PubMed", "id": "16516141", "url": "https://pubmed.ncbi.nlm.nih.gov/16516141" }, { "database": "PubMed", "id": "16960890", "url": "https://pubmed.ncbi.nlm.nih.gov/16960890" }, { "database": "PubMed", "id": "17204522", "url": "https://pubmed.ncbi.nlm.nih.gov/17204522" }, { "database": "PubMed", "id": "17242212", "url": "https://pubmed.ncbi.nlm.nih.gov/17242212" }, { "database": "PubMed", "id": "17360977", "url": "https://pubmed.ncbi.nlm.nih.gov/17360977" }, { "database": "PubMed", "id": "17647275", "url": "https://pubmed.ncbi.nlm.nih.gov/17647275" }, { "database": "PubMed", "id": "18160431", "url": "https://pubmed.ncbi.nlm.nih.gov/18160431" }, { "database": "PubMed", "id": "19501568", "url": "https://pubmed.ncbi.nlm.nih.gov/19501568" }, { "database": "PubMed", "id": "19567513", "url": "https://pubmed.ncbi.nlm.nih.gov/19567513" }, { "database": "PubMed", "id": "19593406", "url": "https://pubmed.ncbi.nlm.nih.gov/19593406" }, { "database": "PubMed", "id": "20393162", "url": "https://pubmed.ncbi.nlm.nih.gov/20393162" }, { "database": "PubMed", "id": "20685959", "url": "https://pubmed.ncbi.nlm.nih.gov/20685959" }, { "database": "PubMed", "id": "20863384", "url": "https://pubmed.ncbi.nlm.nih.gov/20863384" }, { "database": "PubMed", "id": "21040800", "url": "https://pubmed.ncbi.nlm.nih.gov/21040800" }, { "database": "PubMed", "id": "21252690", "url": "https://pubmed.ncbi.nlm.nih.gov/21252690" }, { "database": "PubMed", "id": "21589939", "url": "https://pubmed.ncbi.nlm.nih.gov/21589939" }, { "database": "PubMed", "id": "21852229", "url": "https://pubmed.ncbi.nlm.nih.gov/21852229" }, { "database": "PubMed", "id": "21937042", "url": "https://pubmed.ncbi.nlm.nih.gov/21937042" }, { "database": "PubMed", "id": "22348058", "url": "https://pubmed.ncbi.nlm.nih.gov/22348058" }, { "database": "PubMed", "id": "22457223", "url": "https://pubmed.ncbi.nlm.nih.gov/22457223" }, { "database": "PubMed", "id": "22862962", "url": "https://pubmed.ncbi.nlm.nih.gov/22862962" }, { "database": "PubMed", "id": "25580119", "url": "https://pubmed.ncbi.nlm.nih.gov/25580119" }, { "database": "PubMed", "id": "27207509", "url": "https://pubmed.ncbi.nlm.nih.gov/27207509" }, { "database": "PubMed", "id": "27340831", "url": "https://pubmed.ncbi.nlm.nih.gov/27340831" }, { "database": "PubMed", "id": "32536688", "url": "https://pubmed.ncbi.nlm.nih.gov/32536688" }, { "database": "PubMed", "id": "33173197", "url": "https://pubmed.ncbi.nlm.nih.gov/33173197" }, { "database": "PubMed", "id": "35833836", "url": "https://pubmed.ncbi.nlm.nih.gov/35833836" }, { "database": "PubMed", "id": "18498745", "url": "https://pubmed.ncbi.nlm.nih.gov/18498745" } ], "site_lbl": "Ser312", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 636, "end_pos": 636, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by RPS6KB1", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "16131083", "url": "https://pubmed.ncbi.nlm.nih.gov/16131083" }, { "database": "PubMed", "id": "19651622", "url": "https://pubmed.ncbi.nlm.nih.gov/19651622" }, { "database": "PubMed", "id": "16354680", "url": "https://pubmed.ncbi.nlm.nih.gov/16354680" }, { "database": "PubMed", "id": "11287630", "url": "https://pubmed.ncbi.nlm.nih.gov/11287630" }, { "database": "PubMed", "id": "12765939", "url": "https://pubmed.ncbi.nlm.nih.gov/12765939" }, { "database": "PubMed", "id": "14769130", "url": "https://pubmed.ncbi.nlm.nih.gov/14769130" }, { "database": "PubMed", "id": "15576463", "url": "https://pubmed.ncbi.nlm.nih.gov/15576463" }, { "database": "PubMed", "id": "16123357", "url": "https://pubmed.ncbi.nlm.nih.gov/16123357" }, { "database": "PubMed", "id": "16284649", "url": "https://pubmed.ncbi.nlm.nih.gov/16284649" }, { "database": "PubMed", "id": "17360977", "url": "https://pubmed.ncbi.nlm.nih.gov/17360977" }, { "database": "PubMed", "id": "17640984", "url": "https://pubmed.ncbi.nlm.nih.gov/17640984" }, { "database": "PubMed", "id": "18597775", "url": "https://pubmed.ncbi.nlm.nih.gov/18597775" }, { "database": "PubMed", "id": "18952604", "url": "https://pubmed.ncbi.nlm.nih.gov/18952604" }, { "database": "PubMed", "id": "19561084", "url": "https://pubmed.ncbi.nlm.nih.gov/19561084" }, { "database": "PubMed", "id": "19581421", "url": "https://pubmed.ncbi.nlm.nih.gov/19581421" }, { "database": "PubMed", "id": "20203102", "url": "https://pubmed.ncbi.nlm.nih.gov/20203102" }, { "database": "PubMed", "id": "21478152", "url": "https://pubmed.ncbi.nlm.nih.gov/21478152" }, { "database": "PubMed", "id": "21829658", "url": "https://pubmed.ncbi.nlm.nih.gov/21829658" }, { "database": "PubMed", "id": "22348058", "url": "https://pubmed.ncbi.nlm.nih.gov/22348058" }, { "database": "PubMed", "id": "22966072", "url": "https://pubmed.ncbi.nlm.nih.gov/22966072" }, { "database": "PubMed", "id": "23512499", "url": "https://pubmed.ncbi.nlm.nih.gov/23512499" }, { "database": "PubMed", "id": "25667991", "url": "https://pubmed.ncbi.nlm.nih.gov/25667991" }, { "database": "PubMed", "id": "25799226", "url": "https://pubmed.ncbi.nlm.nih.gov/25799226" }, { "database": "PubMed", "id": "25813876", "url": "https://pubmed.ncbi.nlm.nih.gov/25813876" }, { "database": "PubMed", "id": "26077338", "url": "https://pubmed.ncbi.nlm.nih.gov/26077338" }, { "database": "PubMed", "id": "27434075", "url": "https://pubmed.ncbi.nlm.nih.gov/27434075" }, { "database": "PubMed", "id": "28652303", "url": "https://pubmed.ncbi.nlm.nih.gov/28652303" }, { "database": "PubMed", "id": "28934129", "url": "https://pubmed.ncbi.nlm.nih.gov/28934129" }, { "database": "PubMed", "id": "30381640", "url": "https://pubmed.ncbi.nlm.nih.gov/30381640" }, { "database": "PubMed", "id": "36111162", "url": "https://pubmed.ncbi.nlm.nih.gov/36111162" }, { "database": "PubMed", "id": "18498745", "url": "https://pubmed.ncbi.nlm.nih.gov/18498745" }, { "database": "PubMed", "id": "17081983", "url": "https://pubmed.ncbi.nlm.nih.gov/17081983" } ], "site_lbl": "Ser636", "uniprot_canonical_ac": "P35568-1" } ], "record_id": "pubmed.16284649", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Nutrients suppress phosphatidylinositol 3-kinase/Akt signaling via raptor-dependent mTOR-mediated insulin receptor substrate 1 phosphorylation.", "journal": "Molecular and cellular biology", "date": "2006", "authors": "Tzatsos A, Kandror KV", "reference": { "type": "PubMed", "id": "16354680", "url": "https://pubmed.ncbi.nlm.nih.gov/16354680" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 616, "end_pos": 616, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "16354680", "url": "https://pubmed.ncbi.nlm.nih.gov/16354680" }, { "database": "PubMed", "id": "8626671", "url": "https://pubmed.ncbi.nlm.nih.gov/8626671" }, { "database": "PubMed", "id": "14769130", "url": "https://pubmed.ncbi.nlm.nih.gov/14769130" }, { "database": "PubMed", "id": "15044323", "url": "https://pubmed.ncbi.nlm.nih.gov/15044323" }, { "database": "PubMed", "id": "15713122", "url": "https://pubmed.ncbi.nlm.nih.gov/15713122" }, { "database": "PubMed", "id": "17242212", "url": "https://pubmed.ncbi.nlm.nih.gov/17242212" }, { "database": "PubMed", "id": "17360977", "url": "https://pubmed.ncbi.nlm.nih.gov/17360977" }, { "database": "PubMed", "id": "17640984", "url": "https://pubmed.ncbi.nlm.nih.gov/17640984" }, { "database": "PubMed", "id": "21937042", "url": "https://pubmed.ncbi.nlm.nih.gov/21937042" }, { "database": "PubMed", "id": "22476197", "url": "https://pubmed.ncbi.nlm.nih.gov/22476197" }, { "database": "PubMed", "id": "26297026", "url": "https://pubmed.ncbi.nlm.nih.gov/26297026" } ], "site_lbl": "Ser616", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 636, "end_pos": 636, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by RPS6KB1", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "16131083", "url": "https://pubmed.ncbi.nlm.nih.gov/16131083" }, { "database": "PubMed", "id": "19651622", "url": "https://pubmed.ncbi.nlm.nih.gov/19651622" }, { "database": "PubMed", "id": "16354680", "url": "https://pubmed.ncbi.nlm.nih.gov/16354680" }, { "database": "PubMed", "id": "11287630", "url": "https://pubmed.ncbi.nlm.nih.gov/11287630" }, { "database": "PubMed", "id": "12765939", "url": "https://pubmed.ncbi.nlm.nih.gov/12765939" }, { "database": "PubMed", "id": "14769130", "url": "https://pubmed.ncbi.nlm.nih.gov/14769130" }, { "database": "PubMed", "id": "15576463", "url": "https://pubmed.ncbi.nlm.nih.gov/15576463" }, { "database": "PubMed", "id": "16123357", "url": "https://pubmed.ncbi.nlm.nih.gov/16123357" }, { "database": "PubMed", "id": "16284649", "url": "https://pubmed.ncbi.nlm.nih.gov/16284649" }, { "database": "PubMed", "id": "17360977", "url": "https://pubmed.ncbi.nlm.nih.gov/17360977" }, { "database": "PubMed", "id": "17640984", "url": "https://pubmed.ncbi.nlm.nih.gov/17640984" }, { "database": "PubMed", "id": "18597775", "url": "https://pubmed.ncbi.nlm.nih.gov/18597775" }, { "database": "PubMed", "id": "18952604", "url": "https://pubmed.ncbi.nlm.nih.gov/18952604" }, { "database": "PubMed", "id": "19561084", "url": "https://pubmed.ncbi.nlm.nih.gov/19561084" }, { "database": "PubMed", "id": "19581421", "url": "https://pubmed.ncbi.nlm.nih.gov/19581421" }, { "database": "PubMed", "id": "20203102", "url": "https://pubmed.ncbi.nlm.nih.gov/20203102" }, { "database": "PubMed", "id": "21478152", "url": "https://pubmed.ncbi.nlm.nih.gov/21478152" }, { "database": "PubMed", "id": "21829658", "url": "https://pubmed.ncbi.nlm.nih.gov/21829658" }, { "database": "PubMed", "id": "22348058", "url": "https://pubmed.ncbi.nlm.nih.gov/22348058" }, { "database": "PubMed", "id": "22966072", "url": "https://pubmed.ncbi.nlm.nih.gov/22966072" }, { "database": "PubMed", "id": "23512499", "url": "https://pubmed.ncbi.nlm.nih.gov/23512499" }, { "database": "PubMed", "id": "25667991", "url": "https://pubmed.ncbi.nlm.nih.gov/25667991" }, { "database": "PubMed", "id": "25799226", "url": "https://pubmed.ncbi.nlm.nih.gov/25799226" }, { "database": "PubMed", "id": "25813876", "url": "https://pubmed.ncbi.nlm.nih.gov/25813876" }, { "database": "PubMed", "id": "26077338", "url": "https://pubmed.ncbi.nlm.nih.gov/26077338" }, { "database": "PubMed", "id": "27434075", "url": "https://pubmed.ncbi.nlm.nih.gov/27434075" }, { "database": "PubMed", "id": "28652303", "url": "https://pubmed.ncbi.nlm.nih.gov/28652303" }, { "database": "PubMed", "id": "28934129", "url": "https://pubmed.ncbi.nlm.nih.gov/28934129" }, { "database": "PubMed", "id": "30381640", "url": "https://pubmed.ncbi.nlm.nih.gov/30381640" }, { "database": "PubMed", "id": "36111162", "url": "https://pubmed.ncbi.nlm.nih.gov/36111162" }, { "database": "PubMed", "id": "18498745", "url": "https://pubmed.ncbi.nlm.nih.gov/18498745" }, { "database": "PubMed", "id": "17081983", "url": "https://pubmed.ncbi.nlm.nih.gov/17081983" } ], "site_lbl": "Ser636", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 639, "end_pos": 639, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "16354680", "url": "https://pubmed.ncbi.nlm.nih.gov/16354680" }, { "database": "PubMed", "id": "11287630", "url": "https://pubmed.ncbi.nlm.nih.gov/11287630" }, { "database": "PubMed", "id": "14769130", "url": "https://pubmed.ncbi.nlm.nih.gov/14769130" }, { "database": "PubMed", "id": "15576463", "url": "https://pubmed.ncbi.nlm.nih.gov/15576463" }, { "database": "PubMed", "id": "16123357", "url": "https://pubmed.ncbi.nlm.nih.gov/16123357" }, { "database": "PubMed", "id": "19561084", "url": "https://pubmed.ncbi.nlm.nih.gov/19561084" }, { "database": "PubMed", "id": "20203102", "url": "https://pubmed.ncbi.nlm.nih.gov/20203102" }, { "database": "PubMed", "id": "21478152", "url": "https://pubmed.ncbi.nlm.nih.gov/21478152" }, { "database": "PubMed", "id": "21829658", "url": "https://pubmed.ncbi.nlm.nih.gov/21829658" }, { "database": "PubMed", "id": "23512499", "url": "https://pubmed.ncbi.nlm.nih.gov/23512499" }, { "database": "PubMed", "id": "25667991", "url": "https://pubmed.ncbi.nlm.nih.gov/25667991" }, { "database": "PubMed", "id": "25799226", "url": "https://pubmed.ncbi.nlm.nih.gov/25799226" }, { "database": "PubMed", "id": "30381640", "url": "https://pubmed.ncbi.nlm.nih.gov/30381640" } ], "site_lbl": "Ser639", "uniprot_canonical_ac": "P35568-1" } ], "record_id": "pubmed.16354680", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Enhanced mitogenic signaling in skeletal muscle of women with polycystic ovary syndrome.", "journal": "Diabetes", "date": "2006", "authors": "Corbould A, Zhao H, Mirzoeva S, Aird F, Dunaif A", "reference": { "type": "PubMed", "id": "16505239", "url": "https://pubmed.ncbi.nlm.nih.gov/16505239" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 312, "end_pos": 312, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by IKKB, MAPK8 and RPS6KB1", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "12351658", "url": "https://pubmed.ncbi.nlm.nih.gov/12351658" }, { "database": "PubMed", "id": "12510059", "url": "https://pubmed.ncbi.nlm.nih.gov/12510059" }, { "database": "PubMed", "id": "14769130", "url": "https://pubmed.ncbi.nlm.nih.gov/14769130" }, { "database": "PubMed", "id": "15044323", "url": "https://pubmed.ncbi.nlm.nih.gov/15044323" }, { "database": "PubMed", "id": "15613682", "url": "https://pubmed.ncbi.nlm.nih.gov/15613682" }, { "database": "PubMed", "id": "15713122", "url": "https://pubmed.ncbi.nlm.nih.gov/15713122" }, { "database": "PubMed", "id": "15952059", "url": "https://pubmed.ncbi.nlm.nih.gov/15952059" }, { "database": "PubMed", "id": "16123357", "url": "https://pubmed.ncbi.nlm.nih.gov/16123357" }, { "database": "PubMed", "id": "16284649", "url": "https://pubmed.ncbi.nlm.nih.gov/16284649" }, { "database": "PubMed", "id": "16505239", "url": "https://pubmed.ncbi.nlm.nih.gov/16505239" }, { "database": "PubMed", "id": "16505244", "url": "https://pubmed.ncbi.nlm.nih.gov/16505244" }, { "database": "PubMed", "id": "16516141", "url": "https://pubmed.ncbi.nlm.nih.gov/16516141" }, { "database": "PubMed", "id": "16960890", "url": "https://pubmed.ncbi.nlm.nih.gov/16960890" }, { "database": "PubMed", "id": "17204522", "url": "https://pubmed.ncbi.nlm.nih.gov/17204522" }, { "database": "PubMed", "id": "17242212", "url": "https://pubmed.ncbi.nlm.nih.gov/17242212" }, { "database": "PubMed", "id": "17360977", "url": "https://pubmed.ncbi.nlm.nih.gov/17360977" }, { "database": "PubMed", "id": "17647275", "url": "https://pubmed.ncbi.nlm.nih.gov/17647275" }, { "database": "PubMed", "id": "18160431", "url": "https://pubmed.ncbi.nlm.nih.gov/18160431" }, { "database": "PubMed", "id": "19501568", "url": "https://pubmed.ncbi.nlm.nih.gov/19501568" }, { "database": "PubMed", "id": "19567513", "url": "https://pubmed.ncbi.nlm.nih.gov/19567513" }, { "database": "PubMed", "id": "19593406", "url": "https://pubmed.ncbi.nlm.nih.gov/19593406" }, { "database": "PubMed", "id": "20393162", "url": "https://pubmed.ncbi.nlm.nih.gov/20393162" }, { "database": "PubMed", "id": "20685959", "url": "https://pubmed.ncbi.nlm.nih.gov/20685959" }, { "database": "PubMed", "id": "20863384", "url": "https://pubmed.ncbi.nlm.nih.gov/20863384" }, { "database": "PubMed", "id": "21040800", "url": "https://pubmed.ncbi.nlm.nih.gov/21040800" }, { "database": "PubMed", "id": "21252690", "url": "https://pubmed.ncbi.nlm.nih.gov/21252690" }, { "database": "PubMed", "id": "21589939", "url": "https://pubmed.ncbi.nlm.nih.gov/21589939" }, { "database": "PubMed", "id": "21852229", "url": "https://pubmed.ncbi.nlm.nih.gov/21852229" }, { "database": "PubMed", "id": "21937042", "url": "https://pubmed.ncbi.nlm.nih.gov/21937042" }, { "database": "PubMed", "id": "22348058", "url": "https://pubmed.ncbi.nlm.nih.gov/22348058" }, { "database": "PubMed", "id": "22457223", "url": "https://pubmed.ncbi.nlm.nih.gov/22457223" }, { "database": "PubMed", "id": "22862962", "url": "https://pubmed.ncbi.nlm.nih.gov/22862962" }, { "database": "PubMed", "id": "25580119", "url": "https://pubmed.ncbi.nlm.nih.gov/25580119" }, { "database": "PubMed", "id": "27207509", "url": "https://pubmed.ncbi.nlm.nih.gov/27207509" }, { "database": "PubMed", "id": "27340831", "url": "https://pubmed.ncbi.nlm.nih.gov/27340831" }, { "database": "PubMed", "id": "32536688", "url": "https://pubmed.ncbi.nlm.nih.gov/32536688" }, { "database": "PubMed", "id": "33173197", "url": "https://pubmed.ncbi.nlm.nih.gov/33173197" }, { "database": "PubMed", "id": "35833836", "url": "https://pubmed.ncbi.nlm.nih.gov/35833836" }, { "database": "PubMed", "id": "18498745", "url": "https://pubmed.ncbi.nlm.nih.gov/18498745" } ], "site_lbl": "Ser312", "uniprot_canonical_ac": "P35568-1" } ], "record_id": "pubmed.16505239", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "IRS-1 serine phosphorylation and insulin resistance in skeletal muscle from pancreas transplant recipients.", "journal": "Diabetes", "date": "2006", "authors": "Bouzakri K, Karlsson HK, Vestergaard H, Madsbad S, Christiansen E, Zierath JR", "reference": { "type": "PubMed", "id": "16505244", "url": "https://pubmed.ncbi.nlm.nih.gov/16505244" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 312, "end_pos": 312, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by IKKB, MAPK8 and RPS6KB1", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "12351658", "url": "https://pubmed.ncbi.nlm.nih.gov/12351658" }, { "database": "PubMed", "id": "12510059", "url": "https://pubmed.ncbi.nlm.nih.gov/12510059" }, { "database": "PubMed", "id": "14769130", "url": "https://pubmed.ncbi.nlm.nih.gov/14769130" }, { "database": "PubMed", "id": "15044323", "url": "https://pubmed.ncbi.nlm.nih.gov/15044323" }, { "database": "PubMed", "id": "15613682", "url": "https://pubmed.ncbi.nlm.nih.gov/15613682" }, { "database": "PubMed", "id": "15713122", "url": "https://pubmed.ncbi.nlm.nih.gov/15713122" }, { "database": "PubMed", "id": "15952059", "url": "https://pubmed.ncbi.nlm.nih.gov/15952059" }, { "database": "PubMed", "id": "16123357", "url": "https://pubmed.ncbi.nlm.nih.gov/16123357" }, { "database": "PubMed", "id": "16284649", "url": "https://pubmed.ncbi.nlm.nih.gov/16284649" }, { "database": "PubMed", "id": "16505239", "url": "https://pubmed.ncbi.nlm.nih.gov/16505239" }, { "database": "PubMed", "id": "16505244", "url": "https://pubmed.ncbi.nlm.nih.gov/16505244" }, { "database": "PubMed", "id": "16516141", "url": "https://pubmed.ncbi.nlm.nih.gov/16516141" }, { "database": "PubMed", "id": "16960890", "url": "https://pubmed.ncbi.nlm.nih.gov/16960890" }, { "database": "PubMed", "id": "17204522", "url": "https://pubmed.ncbi.nlm.nih.gov/17204522" }, { "database": "PubMed", "id": "17242212", "url": "https://pubmed.ncbi.nlm.nih.gov/17242212" }, { "database": "PubMed", "id": "17360977", "url": "https://pubmed.ncbi.nlm.nih.gov/17360977" }, { "database": "PubMed", "id": "17647275", "url": "https://pubmed.ncbi.nlm.nih.gov/17647275" }, { "database": "PubMed", "id": "18160431", "url": "https://pubmed.ncbi.nlm.nih.gov/18160431" }, { "database": "PubMed", "id": "19501568", "url": "https://pubmed.ncbi.nlm.nih.gov/19501568" }, { "database": "PubMed", "id": "19567513", "url": "https://pubmed.ncbi.nlm.nih.gov/19567513" }, { "database": "PubMed", "id": "19593406", "url": "https://pubmed.ncbi.nlm.nih.gov/19593406" }, { "database": "PubMed", "id": "20393162", "url": "https://pubmed.ncbi.nlm.nih.gov/20393162" }, { "database": "PubMed", "id": "20685959", "url": "https://pubmed.ncbi.nlm.nih.gov/20685959" }, { "database": "PubMed", "id": "20863384", "url": "https://pubmed.ncbi.nlm.nih.gov/20863384" }, { "database": "PubMed", "id": "21040800", "url": "https://pubmed.ncbi.nlm.nih.gov/21040800" }, { "database": "PubMed", "id": "21252690", "url": "https://pubmed.ncbi.nlm.nih.gov/21252690" }, { "database": "PubMed", "id": "21589939", "url": "https://pubmed.ncbi.nlm.nih.gov/21589939" }, { "database": "PubMed", "id": "21852229", "url": "https://pubmed.ncbi.nlm.nih.gov/21852229" }, { "database": "PubMed", "id": "21937042", "url": "https://pubmed.ncbi.nlm.nih.gov/21937042" }, { "database": "PubMed", "id": "22348058", "url": "https://pubmed.ncbi.nlm.nih.gov/22348058" }, { "database": "PubMed", "id": "22457223", "url": "https://pubmed.ncbi.nlm.nih.gov/22457223" }, { "database": "PubMed", "id": "22862962", "url": "https://pubmed.ncbi.nlm.nih.gov/22862962" }, { "database": "PubMed", "id": "25580119", "url": "https://pubmed.ncbi.nlm.nih.gov/25580119" }, { "database": "PubMed", "id": "27207509", "url": "https://pubmed.ncbi.nlm.nih.gov/27207509" }, { "database": "PubMed", "id": "27340831", "url": "https://pubmed.ncbi.nlm.nih.gov/27340831" }, { "database": "PubMed", "id": "32536688", "url": "https://pubmed.ncbi.nlm.nih.gov/32536688" }, { "database": "PubMed", "id": "33173197", "url": "https://pubmed.ncbi.nlm.nih.gov/33173197" }, { "database": "PubMed", "id": "35833836", "url": "https://pubmed.ncbi.nlm.nih.gov/35833836" }, { "database": "PubMed", "id": "18498745", "url": "https://pubmed.ncbi.nlm.nih.gov/18498745" } ], "site_lbl": "Ser312", "uniprot_canonical_ac": "P35568-1" } ], "record_id": "pubmed.16505244", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Phosphorylation of IRS1 at serine 307 and serine 312 in response to insulin in human adipocytes.", "journal": "Biochemical and biophysical research communications", "date": "2006", "authors": "Danielsson A, Nystrom FH, Stralfors P", "reference": { "type": "PubMed", "id": "16516141", "url": "https://pubmed.ncbi.nlm.nih.gov/16516141" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 307, "end_pos": 307, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by RPS6KB1", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "11160134", "url": "https://pubmed.ncbi.nlm.nih.gov/11160134" }, { "database": "PubMed", "id": "11606564", "url": "https://pubmed.ncbi.nlm.nih.gov/11606564" }, { "database": "PubMed", "id": "12409308", "url": "https://pubmed.ncbi.nlm.nih.gov/12409308" }, { "database": "PubMed", "id": "12714600", "url": "https://pubmed.ncbi.nlm.nih.gov/12714600" }, { "database": "PubMed", "id": "12730242", "url": "https://pubmed.ncbi.nlm.nih.gov/12730242" }, { "database": "PubMed", "id": "14556646", "url": "https://pubmed.ncbi.nlm.nih.gov/14556646" }, { "database": "PubMed", "id": "14583092", "url": "https://pubmed.ncbi.nlm.nih.gov/14583092" }, { "database": "PubMed", "id": "14641015", "url": "https://pubmed.ncbi.nlm.nih.gov/14641015" }, { "database": "PubMed", "id": "14697666", "url": "https://pubmed.ncbi.nlm.nih.gov/14697666" }, { "database": "PubMed", "id": "15020250", "url": "https://pubmed.ncbi.nlm.nih.gov/15020250" }, { "database": "PubMed", "id": "15153564", "url": "https://pubmed.ncbi.nlm.nih.gov/15153564" }, { "database": "PubMed", "id": "15582605", "url": "https://pubmed.ncbi.nlm.nih.gov/15582605" }, { "database": "PubMed", "id": "15802620", "url": "https://pubmed.ncbi.nlm.nih.gov/15802620" }, { "database": "PubMed", "id": "16046301", "url": "https://pubmed.ncbi.nlm.nih.gov/16046301" }, { "database": "PubMed", "id": "16055440", "url": "https://pubmed.ncbi.nlm.nih.gov/16055440" }, { "database": "PubMed", "id": "16099428", "url": "https://pubmed.ncbi.nlm.nih.gov/16099428" }, { "database": "PubMed", "id": "16210322", "url": "https://pubmed.ncbi.nlm.nih.gov/16210322" }, { "database": "PubMed", "id": "16269459", "url": "https://pubmed.ncbi.nlm.nih.gov/16269459" }, { "database": "PubMed", "id": "16516141", "url": "https://pubmed.ncbi.nlm.nih.gov/16516141" }, { "database": "PubMed", "id": "16754954", "url": "https://pubmed.ncbi.nlm.nih.gov/16754954" }, { "database": "PubMed", "id": "16839860", "url": "https://pubmed.ncbi.nlm.nih.gov/16839860" }, { "database": "PubMed", "id": "17077083", "url": "https://pubmed.ncbi.nlm.nih.gov/17077083" }, { "database": "PubMed", "id": "17095576", "url": "https://pubmed.ncbi.nlm.nih.gov/17095576" }, { "database": "PubMed", "id": "17276034", "url": "https://pubmed.ncbi.nlm.nih.gov/17276034" }, { "database": "PubMed", "id": "17481767", "url": "https://pubmed.ncbi.nlm.nih.gov/17481767" }, { "database": "PubMed", "id": "17575262", "url": "https://pubmed.ncbi.nlm.nih.gov/17575262" }, { "database": "PubMed", "id": "18187553", "url": "https://pubmed.ncbi.nlm.nih.gov/18187553" }, { "database": "PubMed", "id": "18372392", "url": "https://pubmed.ncbi.nlm.nih.gov/18372392" }, { "database": "PubMed", "id": "18380932", "url": "https://pubmed.ncbi.nlm.nih.gov/18380932" }, { "database": "PubMed", "id": "18496818", "url": "https://pubmed.ncbi.nlm.nih.gov/18496818" }, { "database": "PubMed", "id": "18952604", "url": "https://pubmed.ncbi.nlm.nih.gov/18952604" }, { "database": "PubMed", "id": "19095745", "url": "https://pubmed.ncbi.nlm.nih.gov/19095745" }, { "database": "PubMed", "id": "19524129", "url": "https://pubmed.ncbi.nlm.nih.gov/19524129" }, { "database": "PubMed", "id": "19897715", "url": "https://pubmed.ncbi.nlm.nih.gov/19897715" }, { "database": "PubMed", "id": "20351777", "url": "https://pubmed.ncbi.nlm.nih.gov/20351777" }, { "database": "PubMed", "id": "20382011", "url": "https://pubmed.ncbi.nlm.nih.gov/20382011" }, { "database": "PubMed", "id": "20384568", "url": "https://pubmed.ncbi.nlm.nih.gov/20384568" }, { "database": "PubMed", "id": "20541543", "url": "https://pubmed.ncbi.nlm.nih.gov/20541543" }, { "database": "PubMed", "id": "20587749", "url": "https://pubmed.ncbi.nlm.nih.gov/20587749" }, { "database": "PubMed", "id": "20594161", "url": "https://pubmed.ncbi.nlm.nih.gov/20594161" }, { "database": "PubMed", "id": "20594757", "url": "https://pubmed.ncbi.nlm.nih.gov/20594757" }, { "database": "PubMed", "id": "20702573", "url": "https://pubmed.ncbi.nlm.nih.gov/20702573" }, { "database": "PubMed", "id": "21119656", "url": "https://pubmed.ncbi.nlm.nih.gov/21119656" }, { "database": "PubMed", "id": "21478152", "url": "https://pubmed.ncbi.nlm.nih.gov/21478152" }, { "database": "PubMed", "id": "21505982", "url": "https://pubmed.ncbi.nlm.nih.gov/21505982" }, { "database": "PubMed", "id": "21786209", "url": "https://pubmed.ncbi.nlm.nih.gov/21786209" }, { "database": "PubMed", "id": "21852229", "url": "https://pubmed.ncbi.nlm.nih.gov/21852229" }, { "database": "PubMed", "id": "21900690", "url": "https://pubmed.ncbi.nlm.nih.gov/21900690" }, { "database": "PubMed", "id": "22046423", "url": "https://pubmed.ncbi.nlm.nih.gov/22046423" }, { "database": "PubMed", "id": "22227580", "url": "https://pubmed.ncbi.nlm.nih.gov/22227580" }, { "database": "PubMed", "id": "22266116", "url": "https://pubmed.ncbi.nlm.nih.gov/22266116" }, { "database": "PubMed", "id": "22328823", "url": "https://pubmed.ncbi.nlm.nih.gov/22328823" }, { "database": "PubMed", "id": "22348058", "url": "https://pubmed.ncbi.nlm.nih.gov/22348058" }, { "database": "PubMed", "id": "22491740", "url": "https://pubmed.ncbi.nlm.nih.gov/22491740" }, { "database": "PubMed", "id": "22728372", "url": "https://pubmed.ncbi.nlm.nih.gov/22728372" }, { "database": "PubMed", "id": "22766331", "url": "https://pubmed.ncbi.nlm.nih.gov/22766331" }, { "database": "PubMed", "id": "23095254", "url": "https://pubmed.ncbi.nlm.nih.gov/23095254" }, { "database": "PubMed", "id": "23174405", "url": "https://pubmed.ncbi.nlm.nih.gov/23174405" }, { "database": "PubMed", "id": "23182460", "url": "https://pubmed.ncbi.nlm.nih.gov/23182460" }, { "database": "PubMed", "id": "23481042", "url": "https://pubmed.ncbi.nlm.nih.gov/23481042" }, { "database": "PubMed", "id": "23566306", "url": "https://pubmed.ncbi.nlm.nih.gov/23566306" }, { "database": "PubMed", "id": "23592917", "url": "https://pubmed.ncbi.nlm.nih.gov/23592917" }, { "database": "PubMed", "id": "23891856", "url": "https://pubmed.ncbi.nlm.nih.gov/23891856" }, { "database": "PubMed", "id": "23958494", "url": "https://pubmed.ncbi.nlm.nih.gov/23958494" }, { "database": "PubMed", "id": "24068326", "url": "https://pubmed.ncbi.nlm.nih.gov/24068326" }, { "database": "PubMed", "id": "24846082", "url": "https://pubmed.ncbi.nlm.nih.gov/24846082" }, { "database": "PubMed", "id": "25120613", "url": "https://pubmed.ncbi.nlm.nih.gov/25120613" }, { "database": "PubMed", "id": "25355439", "url": "https://pubmed.ncbi.nlm.nih.gov/25355439" }, { "database": "PubMed", "id": "25645159", "url": "https://pubmed.ncbi.nlm.nih.gov/25645159" }, { "database": "PubMed", "id": "25799226", "url": "https://pubmed.ncbi.nlm.nih.gov/25799226" }, { "database": "PubMed", "id": "26604643", "url": "https://pubmed.ncbi.nlm.nih.gov/26604643" }, { "database": "PubMed", "id": "26698173", "url": "https://pubmed.ncbi.nlm.nih.gov/26698173" }, { "database": "PubMed", "id": "26704265", "url": "https://pubmed.ncbi.nlm.nih.gov/26704265" }, { "database": "PubMed", "id": "26899161", "url": "https://pubmed.ncbi.nlm.nih.gov/26899161" }, { "database": "PubMed", "id": "26983645", "url": "https://pubmed.ncbi.nlm.nih.gov/26983645" }, { "database": "PubMed", "id": "27222060", "url": "https://pubmed.ncbi.nlm.nih.gov/27222060" }, { "database": "PubMed", "id": "27506476", "url": "https://pubmed.ncbi.nlm.nih.gov/27506476" }, { "database": "PubMed", "id": "27544192", "url": "https://pubmed.ncbi.nlm.nih.gov/27544192" }, { "database": "PubMed", "id": "27686967", "url": "https://pubmed.ncbi.nlm.nih.gov/27686967" }, { "database": "PubMed", "id": "27936435", "url": "https://pubmed.ncbi.nlm.nih.gov/27936435" }, { "database": "PubMed", "id": "28161417", "url": "https://pubmed.ncbi.nlm.nih.gov/28161417" }, { "database": "PubMed", "id": "28656239", "url": "https://pubmed.ncbi.nlm.nih.gov/28656239" }, { "database": "PubMed", "id": "28731188", "url": "https://pubmed.ncbi.nlm.nih.gov/28731188" }, { "database": "PubMed", "id": "28790390", "url": "https://pubmed.ncbi.nlm.nih.gov/28790390" }, { "database": "PubMed", "id": "28934129", "url": "https://pubmed.ncbi.nlm.nih.gov/28934129" }, { "database": "PubMed", "id": "29177868", "url": "https://pubmed.ncbi.nlm.nih.gov/29177868" }, { "database": "PubMed", "id": "29311680", "url": "https://pubmed.ncbi.nlm.nih.gov/29311680" }, { "database": "PubMed", "id": "29393871", "url": "https://pubmed.ncbi.nlm.nih.gov/29393871" }, { "database": "PubMed", "id": "29432553", "url": "https://pubmed.ncbi.nlm.nih.gov/29432553" }, { "database": "PubMed", "id": "29698741", "url": "https://pubmed.ncbi.nlm.nih.gov/29698741" }, { "database": "PubMed", "id": "29738527", "url": "https://pubmed.ncbi.nlm.nih.gov/29738527" }, { "database": "PubMed", "id": "30240640", "url": "https://pubmed.ncbi.nlm.nih.gov/30240640" }, { "database": "PubMed", "id": "30374127", "url": "https://pubmed.ncbi.nlm.nih.gov/30374127" }, { "database": "PubMed", "id": "30572687", "url": "https://pubmed.ncbi.nlm.nih.gov/30572687" }, { "database": "PubMed", "id": "31137828", "url": "https://pubmed.ncbi.nlm.nih.gov/31137828" }, { "database": "PubMed", "id": "31311314", "url": "https://pubmed.ncbi.nlm.nih.gov/31311314" }, { "database": "PubMed", "id": "31396538", "url": "https://pubmed.ncbi.nlm.nih.gov/31396538" }, { "database": "PubMed", "id": "32875583", "url": "https://pubmed.ncbi.nlm.nih.gov/32875583" }, { "database": "PubMed", "id": "33723215", "url": "https://pubmed.ncbi.nlm.nih.gov/33723215" }, { "database": "PubMed", "id": "35656886", "url": "https://pubmed.ncbi.nlm.nih.gov/35656886" }, { "database": "PubMed", "id": "18498745", "url": "https://pubmed.ncbi.nlm.nih.gov/18498745" } ], "site_lbl": "Ser307", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 312, "end_pos": 312, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by IKKB, MAPK8 and RPS6KB1", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "12351658", "url": "https://pubmed.ncbi.nlm.nih.gov/12351658" }, { "database": "PubMed", "id": "12510059", "url": "https://pubmed.ncbi.nlm.nih.gov/12510059" }, { "database": "PubMed", "id": "14769130", "url": "https://pubmed.ncbi.nlm.nih.gov/14769130" }, { "database": "PubMed", "id": "15044323", "url": "https://pubmed.ncbi.nlm.nih.gov/15044323" }, { "database": "PubMed", "id": "15613682", "url": "https://pubmed.ncbi.nlm.nih.gov/15613682" }, { "database": "PubMed", "id": "15713122", "url": "https://pubmed.ncbi.nlm.nih.gov/15713122" }, { "database": "PubMed", "id": "15952059", "url": "https://pubmed.ncbi.nlm.nih.gov/15952059" }, { "database": "PubMed", "id": "16123357", "url": "https://pubmed.ncbi.nlm.nih.gov/16123357" }, { "database": "PubMed", "id": "16284649", "url": "https://pubmed.ncbi.nlm.nih.gov/16284649" }, { "database": "PubMed", "id": "16505239", "url": "https://pubmed.ncbi.nlm.nih.gov/16505239" }, { "database": "PubMed", "id": "16505244", "url": "https://pubmed.ncbi.nlm.nih.gov/16505244" }, { "database": "PubMed", "id": "16516141", "url": "https://pubmed.ncbi.nlm.nih.gov/16516141" }, { "database": "PubMed", "id": "16960890", "url": "https://pubmed.ncbi.nlm.nih.gov/16960890" }, { "database": "PubMed", "id": "17204522", "url": "https://pubmed.ncbi.nlm.nih.gov/17204522" }, { "database": "PubMed", "id": "17242212", "url": "https://pubmed.ncbi.nlm.nih.gov/17242212" }, { "database": "PubMed", "id": "17360977", "url": "https://pubmed.ncbi.nlm.nih.gov/17360977" }, { "database": "PubMed", "id": "17647275", "url": "https://pubmed.ncbi.nlm.nih.gov/17647275" }, { "database": "PubMed", "id": "18160431", "url": "https://pubmed.ncbi.nlm.nih.gov/18160431" }, { "database": "PubMed", "id": "19501568", "url": "https://pubmed.ncbi.nlm.nih.gov/19501568" }, { "database": "PubMed", "id": "19567513", "url": "https://pubmed.ncbi.nlm.nih.gov/19567513" }, { "database": "PubMed", "id": "19593406", "url": "https://pubmed.ncbi.nlm.nih.gov/19593406" }, { "database": "PubMed", "id": "20393162", "url": "https://pubmed.ncbi.nlm.nih.gov/20393162" }, { "database": "PubMed", "id": "20685959", "url": "https://pubmed.ncbi.nlm.nih.gov/20685959" }, { "database": "PubMed", "id": "20863384", "url": "https://pubmed.ncbi.nlm.nih.gov/20863384" }, { "database": "PubMed", "id": "21040800", "url": "https://pubmed.ncbi.nlm.nih.gov/21040800" }, { "database": "PubMed", "id": "21252690", "url": "https://pubmed.ncbi.nlm.nih.gov/21252690" }, { "database": "PubMed", "id": "21589939", "url": "https://pubmed.ncbi.nlm.nih.gov/21589939" }, { "database": "PubMed", "id": "21852229", "url": "https://pubmed.ncbi.nlm.nih.gov/21852229" }, { "database": "PubMed", "id": "21937042", "url": "https://pubmed.ncbi.nlm.nih.gov/21937042" }, { "database": "PubMed", "id": "22348058", "url": "https://pubmed.ncbi.nlm.nih.gov/22348058" }, { "database": "PubMed", "id": "22457223", "url": "https://pubmed.ncbi.nlm.nih.gov/22457223" }, { "database": "PubMed", "id": "22862962", "url": "https://pubmed.ncbi.nlm.nih.gov/22862962" }, { "database": "PubMed", "id": "25580119", "url": "https://pubmed.ncbi.nlm.nih.gov/25580119" }, { "database": "PubMed", "id": "27207509", "url": "https://pubmed.ncbi.nlm.nih.gov/27207509" }, { "database": "PubMed", "id": "27340831", "url": "https://pubmed.ncbi.nlm.nih.gov/27340831" }, { "database": "PubMed", "id": "32536688", "url": "https://pubmed.ncbi.nlm.nih.gov/32536688" }, { "database": "PubMed", "id": "33173197", "url": "https://pubmed.ncbi.nlm.nih.gov/33173197" }, { "database": "PubMed", "id": "35833836", "url": "https://pubmed.ncbi.nlm.nih.gov/35833836" }, { "database": "PubMed", "id": "18498745", "url": "https://pubmed.ncbi.nlm.nih.gov/18498745" } ], "site_lbl": "Ser312", "uniprot_canonical_ac": "P35568-1" } ], "record_id": "pubmed.16516141", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Regulation of insulin receptor substrate 1 pleckstrin homology domain by protein kinase C: role of serine 24 phosphorylation.", "journal": "Molecular endocrinology (Baltimore, Md.)", "date": "2006", "authors": "Nawaratne R, Gray A, Jorgensen CH, Downes CP, Siddle K, Sethi JK", "reference": { "type": "PubMed", "id": "16574739", "url": "https://pubmed.ncbi.nlm.nih.gov/16574739" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 24, "end_pos": 24, "kinase_uniprot_canonical_ac": "P17252-1", "kinase_gene_name": "PRKCA", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "16574739", "url": "https://pubmed.ncbi.nlm.nih.gov/16574739" } ], "site_lbl": "Ser24", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 24, "end_pos": 24, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "16574739", "url": "https://pubmed.ncbi.nlm.nih.gov/16574739" }, { "database": "PubMed", "id": "16970908", "url": "https://pubmed.ncbi.nlm.nih.gov/16970908" }, { "database": "PubMed", "id": "25330241", "url": "https://pubmed.ncbi.nlm.nih.gov/25330241" } ], "site_lbl": "Ser24", "uniprot_canonical_ac": "P35568-1" } ], "record_id": "pubmed.16574739", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Leptin down-regulates insulin action through phosphorylation of serine-318 in insulin receptor substrate 1.", "journal": "FASEB journal : official publication of the Federation of American Societies for Experimental Biology", "date": "2006", "authors": "Hennige AM, Stefan N, Kapp K, Lehmann R, Weigert C, Beck A, Moeschel K, Mushack J, Schleicher E, Haring HU", "reference": { "type": "PubMed", "id": "16611834", "url": "https://pubmed.ncbi.nlm.nih.gov/16611834" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 323, "end_pos": 323, "kinase_uniprot_canonical_ac": "Q05655-1", "kinase_gene_name": "PRKCD", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "15069075", "url": "https://pubmed.ncbi.nlm.nih.gov/15069075" }, { "database": "PubMed", "id": "16611834", "url": "https://pubmed.ncbi.nlm.nih.gov/16611834" } ], "site_lbl": "Ser323", "uniprot_canonical_ac": "P35568-1" } ], "record_id": "pubmed.16611834", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Myosin motor Myo1c and its receptor NEMO/IKK-gamma promote TNF-alpha-induced serine307 phosphorylation of IRS-1.", "journal": "The Journal of cell biology", "date": "2006", "authors": "Nakamori Y, Emoto M, Fukuda N, Taguchi A, Okuya S, Tajiri M, Miyagishi M, Taira K, Wada Y, Tanizawa Y", "reference": { "type": "PubMed", "id": "16754954", "url": "https://pubmed.ncbi.nlm.nih.gov/16754954" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 307, "end_pos": 307, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by RPS6KB1", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "11160134", "url": "https://pubmed.ncbi.nlm.nih.gov/11160134" }, { "database": "PubMed", "id": "11606564", "url": "https://pubmed.ncbi.nlm.nih.gov/11606564" }, { "database": "PubMed", "id": "12409308", "url": "https://pubmed.ncbi.nlm.nih.gov/12409308" }, { "database": "PubMed", "id": "12714600", "url": "https://pubmed.ncbi.nlm.nih.gov/12714600" }, { "database": "PubMed", "id": "12730242", "url": "https://pubmed.ncbi.nlm.nih.gov/12730242" }, { "database": "PubMed", "id": "14556646", "url": "https://pubmed.ncbi.nlm.nih.gov/14556646" }, { "database": "PubMed", "id": "14583092", "url": "https://pubmed.ncbi.nlm.nih.gov/14583092" }, { "database": "PubMed", "id": "14641015", "url": "https://pubmed.ncbi.nlm.nih.gov/14641015" }, { "database": "PubMed", "id": "14697666", "url": "https://pubmed.ncbi.nlm.nih.gov/14697666" }, { "database": "PubMed", "id": "15020250", "url": "https://pubmed.ncbi.nlm.nih.gov/15020250" }, { "database": "PubMed", "id": "15153564", "url": "https://pubmed.ncbi.nlm.nih.gov/15153564" }, { "database": "PubMed", "id": "15582605", "url": "https://pubmed.ncbi.nlm.nih.gov/15582605" }, { "database": "PubMed", "id": "15802620", "url": "https://pubmed.ncbi.nlm.nih.gov/15802620" }, { "database": "PubMed", "id": "16046301", "url": "https://pubmed.ncbi.nlm.nih.gov/16046301" }, { "database": "PubMed", "id": "16055440", "url": "https://pubmed.ncbi.nlm.nih.gov/16055440" }, { "database": "PubMed", "id": "16099428", "url": "https://pubmed.ncbi.nlm.nih.gov/16099428" }, { "database": "PubMed", "id": "16210322", "url": "https://pubmed.ncbi.nlm.nih.gov/16210322" }, { "database": "PubMed", "id": "16269459", "url": "https://pubmed.ncbi.nlm.nih.gov/16269459" }, { "database": "PubMed", "id": "16516141", "url": "https://pubmed.ncbi.nlm.nih.gov/16516141" }, { "database": "PubMed", "id": "16754954", "url": "https://pubmed.ncbi.nlm.nih.gov/16754954" }, { "database": "PubMed", "id": "16839860", "url": "https://pubmed.ncbi.nlm.nih.gov/16839860" }, { "database": "PubMed", "id": "17077083", "url": "https://pubmed.ncbi.nlm.nih.gov/17077083" }, { "database": "PubMed", "id": "17095576", "url": "https://pubmed.ncbi.nlm.nih.gov/17095576" }, { "database": "PubMed", "id": "17276034", "url": "https://pubmed.ncbi.nlm.nih.gov/17276034" }, { "database": "PubMed", "id": "17481767", "url": "https://pubmed.ncbi.nlm.nih.gov/17481767" }, { "database": "PubMed", "id": "17575262", "url": "https://pubmed.ncbi.nlm.nih.gov/17575262" }, { "database": "PubMed", "id": "18187553", "url": "https://pubmed.ncbi.nlm.nih.gov/18187553" }, { "database": "PubMed", "id": "18372392", "url": "https://pubmed.ncbi.nlm.nih.gov/18372392" }, { "database": "PubMed", "id": "18380932", "url": "https://pubmed.ncbi.nlm.nih.gov/18380932" }, { "database": "PubMed", "id": "18496818", "url": "https://pubmed.ncbi.nlm.nih.gov/18496818" }, { "database": "PubMed", "id": "18952604", "url": "https://pubmed.ncbi.nlm.nih.gov/18952604" }, { "database": "PubMed", "id": "19095745", "url": "https://pubmed.ncbi.nlm.nih.gov/19095745" }, { "database": "PubMed", "id": "19524129", "url": "https://pubmed.ncbi.nlm.nih.gov/19524129" }, { "database": "PubMed", "id": "19897715", "url": "https://pubmed.ncbi.nlm.nih.gov/19897715" }, { "database": "PubMed", "id": "20351777", "url": "https://pubmed.ncbi.nlm.nih.gov/20351777" }, { "database": "PubMed", "id": "20382011", "url": "https://pubmed.ncbi.nlm.nih.gov/20382011" }, { "database": "PubMed", "id": "20384568", "url": "https://pubmed.ncbi.nlm.nih.gov/20384568" }, { "database": "PubMed", "id": "20541543", "url": "https://pubmed.ncbi.nlm.nih.gov/20541543" }, { "database": "PubMed", "id": "20587749", "url": "https://pubmed.ncbi.nlm.nih.gov/20587749" }, { "database": "PubMed", "id": "20594161", "url": "https://pubmed.ncbi.nlm.nih.gov/20594161" }, { "database": "PubMed", "id": "20594757", "url": "https://pubmed.ncbi.nlm.nih.gov/20594757" }, { "database": "PubMed", "id": "20702573", "url": "https://pubmed.ncbi.nlm.nih.gov/20702573" }, { "database": "PubMed", "id": "21119656", "url": "https://pubmed.ncbi.nlm.nih.gov/21119656" }, { "database": "PubMed", "id": "21478152", "url": "https://pubmed.ncbi.nlm.nih.gov/21478152" }, { "database": "PubMed", "id": "21505982", "url": "https://pubmed.ncbi.nlm.nih.gov/21505982" }, { "database": "PubMed", "id": "21786209", "url": "https://pubmed.ncbi.nlm.nih.gov/21786209" }, { "database": "PubMed", "id": "21852229", "url": "https://pubmed.ncbi.nlm.nih.gov/21852229" }, { "database": "PubMed", "id": "21900690", "url": "https://pubmed.ncbi.nlm.nih.gov/21900690" }, { "database": "PubMed", "id": "22046423", "url": "https://pubmed.ncbi.nlm.nih.gov/22046423" }, { "database": "PubMed", "id": "22227580", "url": "https://pubmed.ncbi.nlm.nih.gov/22227580" }, { "database": "PubMed", "id": "22266116", "url": "https://pubmed.ncbi.nlm.nih.gov/22266116" }, { "database": "PubMed", "id": "22328823", "url": "https://pubmed.ncbi.nlm.nih.gov/22328823" }, { "database": "PubMed", "id": "22348058", "url": "https://pubmed.ncbi.nlm.nih.gov/22348058" }, { "database": "PubMed", "id": "22491740", "url": "https://pubmed.ncbi.nlm.nih.gov/22491740" }, { "database": "PubMed", "id": "22728372", "url": "https://pubmed.ncbi.nlm.nih.gov/22728372" }, { "database": "PubMed", "id": "22766331", "url": "https://pubmed.ncbi.nlm.nih.gov/22766331" }, { "database": "PubMed", "id": "23095254", "url": "https://pubmed.ncbi.nlm.nih.gov/23095254" }, { "database": "PubMed", "id": "23174405", "url": "https://pubmed.ncbi.nlm.nih.gov/23174405" }, { "database": "PubMed", "id": "23182460", "url": "https://pubmed.ncbi.nlm.nih.gov/23182460" }, { "database": "PubMed", "id": "23481042", "url": "https://pubmed.ncbi.nlm.nih.gov/23481042" }, { "database": "PubMed", "id": "23566306", "url": "https://pubmed.ncbi.nlm.nih.gov/23566306" }, { "database": "PubMed", "id": "23592917", "url": "https://pubmed.ncbi.nlm.nih.gov/23592917" }, { "database": "PubMed", "id": "23891856", "url": "https://pubmed.ncbi.nlm.nih.gov/23891856" }, { "database": "PubMed", "id": "23958494", "url": "https://pubmed.ncbi.nlm.nih.gov/23958494" }, { "database": "PubMed", "id": "24068326", "url": "https://pubmed.ncbi.nlm.nih.gov/24068326" }, { "database": "PubMed", "id": "24846082", "url": "https://pubmed.ncbi.nlm.nih.gov/24846082" }, { "database": "PubMed", "id": "25120613", "url": "https://pubmed.ncbi.nlm.nih.gov/25120613" }, { "database": "PubMed", "id": "25355439", "url": "https://pubmed.ncbi.nlm.nih.gov/25355439" }, { "database": "PubMed", "id": "25645159", "url": "https://pubmed.ncbi.nlm.nih.gov/25645159" }, { "database": "PubMed", "id": "25799226", "url": "https://pubmed.ncbi.nlm.nih.gov/25799226" }, { "database": "PubMed", "id": "26604643", "url": "https://pubmed.ncbi.nlm.nih.gov/26604643" }, { "database": "PubMed", "id": "26698173", "url": "https://pubmed.ncbi.nlm.nih.gov/26698173" }, { "database": "PubMed", "id": "26704265", "url": "https://pubmed.ncbi.nlm.nih.gov/26704265" }, { "database": "PubMed", "id": "26899161", "url": "https://pubmed.ncbi.nlm.nih.gov/26899161" }, { "database": "PubMed", "id": "26983645", "url": "https://pubmed.ncbi.nlm.nih.gov/26983645" }, { "database": "PubMed", "id": "27222060", "url": "https://pubmed.ncbi.nlm.nih.gov/27222060" }, { "database": "PubMed", "id": "27506476", "url": "https://pubmed.ncbi.nlm.nih.gov/27506476" }, { "database": "PubMed", "id": "27544192", "url": "https://pubmed.ncbi.nlm.nih.gov/27544192" }, { "database": "PubMed", "id": "27686967", "url": "https://pubmed.ncbi.nlm.nih.gov/27686967" }, { "database": "PubMed", "id": "27936435", "url": "https://pubmed.ncbi.nlm.nih.gov/27936435" }, { "database": "PubMed", "id": "28161417", "url": "https://pubmed.ncbi.nlm.nih.gov/28161417" }, { "database": "PubMed", "id": "28656239", "url": "https://pubmed.ncbi.nlm.nih.gov/28656239" }, { "database": "PubMed", "id": "28731188", "url": "https://pubmed.ncbi.nlm.nih.gov/28731188" }, { "database": "PubMed", "id": "28790390", "url": "https://pubmed.ncbi.nlm.nih.gov/28790390" }, { "database": "PubMed", "id": "28934129", "url": "https://pubmed.ncbi.nlm.nih.gov/28934129" }, { "database": "PubMed", "id": "29177868", "url": "https://pubmed.ncbi.nlm.nih.gov/29177868" }, { "database": "PubMed", "id": "29311680", "url": "https://pubmed.ncbi.nlm.nih.gov/29311680" }, { "database": "PubMed", "id": "29393871", "url": "https://pubmed.ncbi.nlm.nih.gov/29393871" }, { "database": "PubMed", "id": "29432553", "url": "https://pubmed.ncbi.nlm.nih.gov/29432553" }, { "database": "PubMed", "id": "29698741", "url": "https://pubmed.ncbi.nlm.nih.gov/29698741" }, { "database": "PubMed", "id": "29738527", "url": "https://pubmed.ncbi.nlm.nih.gov/29738527" }, { "database": "PubMed", "id": "30240640", "url": "https://pubmed.ncbi.nlm.nih.gov/30240640" }, { "database": "PubMed", "id": "30374127", "url": "https://pubmed.ncbi.nlm.nih.gov/30374127" }, { "database": "PubMed", "id": "30572687", "url": "https://pubmed.ncbi.nlm.nih.gov/30572687" }, { "database": "PubMed", "id": "31137828", "url": "https://pubmed.ncbi.nlm.nih.gov/31137828" }, { "database": "PubMed", "id": "31311314", "url": "https://pubmed.ncbi.nlm.nih.gov/31311314" }, { "database": "PubMed", "id": "31396538", "url": "https://pubmed.ncbi.nlm.nih.gov/31396538" }, { "database": "PubMed", "id": "32875583", "url": "https://pubmed.ncbi.nlm.nih.gov/32875583" }, { "database": "PubMed", "id": "33723215", "url": "https://pubmed.ncbi.nlm.nih.gov/33723215" }, { "database": "PubMed", "id": "35656886", "url": "https://pubmed.ncbi.nlm.nih.gov/35656886" }, { "database": "PubMed", "id": "18498745", "url": "https://pubmed.ncbi.nlm.nih.gov/18498745" } ], "site_lbl": "Ser307", "uniprot_canonical_ac": "P35568-1" } ], "record_id": "pubmed.16754954", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Insulin resistance and cardiovascular risk: New insights from molecular and cellular biology.", "journal": "Trends in cardiovascular medicine", "date": "2006", "authors": "Morisco C, Lembo G, Trimarco B", "reference": { "type": "PubMed", "id": "16839860", "url": "https://pubmed.ncbi.nlm.nih.gov/16839860" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 307, "end_pos": 307, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by RPS6KB1", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "11160134", "url": "https://pubmed.ncbi.nlm.nih.gov/11160134" }, { "database": "PubMed", "id": "11606564", "url": "https://pubmed.ncbi.nlm.nih.gov/11606564" }, { "database": "PubMed", "id": "12409308", "url": "https://pubmed.ncbi.nlm.nih.gov/12409308" }, { "database": "PubMed", "id": "12714600", "url": "https://pubmed.ncbi.nlm.nih.gov/12714600" }, { "database": "PubMed", "id": "12730242", "url": "https://pubmed.ncbi.nlm.nih.gov/12730242" }, { "database": "PubMed", "id": "14556646", "url": "https://pubmed.ncbi.nlm.nih.gov/14556646" }, { "database": "PubMed", "id": "14583092", "url": "https://pubmed.ncbi.nlm.nih.gov/14583092" }, { "database": "PubMed", "id": "14641015", "url": "https://pubmed.ncbi.nlm.nih.gov/14641015" }, { "database": "PubMed", "id": "14697666", "url": "https://pubmed.ncbi.nlm.nih.gov/14697666" }, { "database": "PubMed", "id": "15020250", "url": "https://pubmed.ncbi.nlm.nih.gov/15020250" }, { "database": "PubMed", "id": "15153564", "url": "https://pubmed.ncbi.nlm.nih.gov/15153564" }, { "database": "PubMed", "id": "15582605", "url": "https://pubmed.ncbi.nlm.nih.gov/15582605" }, { "database": "PubMed", "id": "15802620", "url": "https://pubmed.ncbi.nlm.nih.gov/15802620" }, { "database": "PubMed", "id": "16046301", "url": "https://pubmed.ncbi.nlm.nih.gov/16046301" }, { "database": "PubMed", "id": "16055440", "url": "https://pubmed.ncbi.nlm.nih.gov/16055440" }, { "database": "PubMed", "id": "16099428", "url": "https://pubmed.ncbi.nlm.nih.gov/16099428" }, { "database": "PubMed", "id": "16210322", "url": "https://pubmed.ncbi.nlm.nih.gov/16210322" }, { "database": "PubMed", "id": "16269459", "url": "https://pubmed.ncbi.nlm.nih.gov/16269459" }, { "database": "PubMed", "id": "16516141", "url": "https://pubmed.ncbi.nlm.nih.gov/16516141" }, { "database": "PubMed", "id": "16754954", "url": "https://pubmed.ncbi.nlm.nih.gov/16754954" }, { "database": "PubMed", "id": "16839860", "url": "https://pubmed.ncbi.nlm.nih.gov/16839860" }, { "database": "PubMed", "id": "17077083", "url": "https://pubmed.ncbi.nlm.nih.gov/17077083" }, { "database": "PubMed", "id": "17095576", "url": "https://pubmed.ncbi.nlm.nih.gov/17095576" }, { "database": "PubMed", "id": "17276034", "url": "https://pubmed.ncbi.nlm.nih.gov/17276034" }, { "database": "PubMed", "id": "17481767", "url": "https://pubmed.ncbi.nlm.nih.gov/17481767" }, { "database": "PubMed", "id": "17575262", "url": "https://pubmed.ncbi.nlm.nih.gov/17575262" }, { "database": "PubMed", "id": "18187553", "url": "https://pubmed.ncbi.nlm.nih.gov/18187553" }, { "database": "PubMed", "id": "18372392", "url": "https://pubmed.ncbi.nlm.nih.gov/18372392" }, { "database": "PubMed", "id": "18380932", "url": "https://pubmed.ncbi.nlm.nih.gov/18380932" }, { "database": "PubMed", "id": "18496818", "url": "https://pubmed.ncbi.nlm.nih.gov/18496818" }, { "database": "PubMed", "id": "18952604", "url": "https://pubmed.ncbi.nlm.nih.gov/18952604" }, { "database": "PubMed", "id": "19095745", "url": "https://pubmed.ncbi.nlm.nih.gov/19095745" }, { "database": "PubMed", "id": "19524129", "url": "https://pubmed.ncbi.nlm.nih.gov/19524129" }, { "database": "PubMed", "id": "19897715", "url": "https://pubmed.ncbi.nlm.nih.gov/19897715" }, { "database": "PubMed", "id": "20351777", "url": "https://pubmed.ncbi.nlm.nih.gov/20351777" }, { "database": "PubMed", "id": "20382011", "url": "https://pubmed.ncbi.nlm.nih.gov/20382011" }, { "database": "PubMed", "id": "20384568", "url": "https://pubmed.ncbi.nlm.nih.gov/20384568" }, { "database": "PubMed", "id": "20541543", "url": "https://pubmed.ncbi.nlm.nih.gov/20541543" }, { "database": "PubMed", "id": "20587749", "url": "https://pubmed.ncbi.nlm.nih.gov/20587749" }, { "database": "PubMed", "id": "20594161", "url": "https://pubmed.ncbi.nlm.nih.gov/20594161" }, { "database": "PubMed", "id": "20594757", "url": "https://pubmed.ncbi.nlm.nih.gov/20594757" }, { "database": "PubMed", "id": "20702573", "url": "https://pubmed.ncbi.nlm.nih.gov/20702573" }, { "database": "PubMed", "id": "21119656", "url": "https://pubmed.ncbi.nlm.nih.gov/21119656" }, { "database": "PubMed", "id": "21478152", "url": "https://pubmed.ncbi.nlm.nih.gov/21478152" }, { "database": "PubMed", "id": "21505982", "url": "https://pubmed.ncbi.nlm.nih.gov/21505982" }, { "database": "PubMed", "id": "21786209", "url": "https://pubmed.ncbi.nlm.nih.gov/21786209" }, { "database": "PubMed", "id": "21852229", "url": "https://pubmed.ncbi.nlm.nih.gov/21852229" }, { "database": "PubMed", "id": "21900690", "url": "https://pubmed.ncbi.nlm.nih.gov/21900690" }, { "database": "PubMed", "id": "22046423", "url": "https://pubmed.ncbi.nlm.nih.gov/22046423" }, { "database": "PubMed", "id": "22227580", "url": "https://pubmed.ncbi.nlm.nih.gov/22227580" }, { "database": "PubMed", "id": "22266116", "url": "https://pubmed.ncbi.nlm.nih.gov/22266116" }, { "database": "PubMed", "id": "22328823", "url": "https://pubmed.ncbi.nlm.nih.gov/22328823" }, { "database": "PubMed", "id": "22348058", "url": "https://pubmed.ncbi.nlm.nih.gov/22348058" }, { "database": "PubMed", "id": "22491740", "url": "https://pubmed.ncbi.nlm.nih.gov/22491740" }, { "database": "PubMed", "id": "22728372", "url": "https://pubmed.ncbi.nlm.nih.gov/22728372" }, { "database": "PubMed", "id": "22766331", "url": "https://pubmed.ncbi.nlm.nih.gov/22766331" }, { "database": "PubMed", "id": "23095254", "url": "https://pubmed.ncbi.nlm.nih.gov/23095254" }, { "database": "PubMed", "id": "23174405", "url": "https://pubmed.ncbi.nlm.nih.gov/23174405" }, { "database": "PubMed", "id": "23182460", "url": "https://pubmed.ncbi.nlm.nih.gov/23182460" }, { "database": "PubMed", "id": "23481042", "url": "https://pubmed.ncbi.nlm.nih.gov/23481042" }, { "database": "PubMed", "id": "23566306", "url": "https://pubmed.ncbi.nlm.nih.gov/23566306" }, { "database": "PubMed", "id": "23592917", "url": "https://pubmed.ncbi.nlm.nih.gov/23592917" }, { "database": "PubMed", "id": "23891856", "url": "https://pubmed.ncbi.nlm.nih.gov/23891856" }, { "database": "PubMed", "id": "23958494", "url": "https://pubmed.ncbi.nlm.nih.gov/23958494" }, { "database": "PubMed", "id": "24068326", "url": "https://pubmed.ncbi.nlm.nih.gov/24068326" }, { "database": "PubMed", "id": "24846082", "url": "https://pubmed.ncbi.nlm.nih.gov/24846082" }, { "database": "PubMed", "id": "25120613", "url": "https://pubmed.ncbi.nlm.nih.gov/25120613" }, { "database": "PubMed", "id": "25355439", "url": "https://pubmed.ncbi.nlm.nih.gov/25355439" }, { "database": "PubMed", "id": "25645159", "url": "https://pubmed.ncbi.nlm.nih.gov/25645159" }, { "database": "PubMed", "id": "25799226", "url": "https://pubmed.ncbi.nlm.nih.gov/25799226" }, { "database": "PubMed", "id": "26604643", "url": "https://pubmed.ncbi.nlm.nih.gov/26604643" }, { "database": "PubMed", "id": "26698173", "url": "https://pubmed.ncbi.nlm.nih.gov/26698173" }, { "database": "PubMed", "id": "26704265", "url": "https://pubmed.ncbi.nlm.nih.gov/26704265" }, { "database": "PubMed", "id": "26899161", "url": "https://pubmed.ncbi.nlm.nih.gov/26899161" }, { "database": "PubMed", "id": "26983645", "url": "https://pubmed.ncbi.nlm.nih.gov/26983645" }, { "database": "PubMed", "id": "27222060", "url": "https://pubmed.ncbi.nlm.nih.gov/27222060" }, { "database": "PubMed", "id": "27506476", "url": "https://pubmed.ncbi.nlm.nih.gov/27506476" }, { "database": "PubMed", "id": "27544192", "url": "https://pubmed.ncbi.nlm.nih.gov/27544192" }, { "database": "PubMed", "id": "27686967", "url": "https://pubmed.ncbi.nlm.nih.gov/27686967" }, { "database": "PubMed", "id": "27936435", "url": "https://pubmed.ncbi.nlm.nih.gov/27936435" }, { "database": "PubMed", "id": "28161417", "url": "https://pubmed.ncbi.nlm.nih.gov/28161417" }, { "database": "PubMed", "id": "28656239", "url": "https://pubmed.ncbi.nlm.nih.gov/28656239" }, { "database": "PubMed", "id": "28731188", "url": "https://pubmed.ncbi.nlm.nih.gov/28731188" }, { "database": "PubMed", "id": "28790390", "url": "https://pubmed.ncbi.nlm.nih.gov/28790390" }, { "database": "PubMed", "id": "28934129", "url": "https://pubmed.ncbi.nlm.nih.gov/28934129" }, { "database": "PubMed", "id": "29177868", "url": "https://pubmed.ncbi.nlm.nih.gov/29177868" }, { "database": "PubMed", "id": "29311680", "url": "https://pubmed.ncbi.nlm.nih.gov/29311680" }, { "database": "PubMed", "id": "29393871", "url": "https://pubmed.ncbi.nlm.nih.gov/29393871" }, { "database": "PubMed", "id": "29432553", "url": "https://pubmed.ncbi.nlm.nih.gov/29432553" }, { "database": "PubMed", "id": "29698741", "url": "https://pubmed.ncbi.nlm.nih.gov/29698741" }, { "database": "PubMed", "id": "29738527", "url": "https://pubmed.ncbi.nlm.nih.gov/29738527" }, { "database": "PubMed", "id": "30240640", "url": "https://pubmed.ncbi.nlm.nih.gov/30240640" }, { "database": "PubMed", "id": "30374127", "url": "https://pubmed.ncbi.nlm.nih.gov/30374127" }, { "database": "PubMed", "id": "30572687", "url": "https://pubmed.ncbi.nlm.nih.gov/30572687" }, { "database": "PubMed", "id": "31137828", "url": "https://pubmed.ncbi.nlm.nih.gov/31137828" }, { "database": "PubMed", "id": "31311314", "url": "https://pubmed.ncbi.nlm.nih.gov/31311314" }, { "database": "PubMed", "id": "31396538", "url": "https://pubmed.ncbi.nlm.nih.gov/31396538" }, { "database": "PubMed", "id": "32875583", "url": "https://pubmed.ncbi.nlm.nih.gov/32875583" }, { "database": "PubMed", "id": "33723215", "url": "https://pubmed.ncbi.nlm.nih.gov/33723215" }, { "database": "PubMed", "id": "35656886", "url": "https://pubmed.ncbi.nlm.nih.gov/35656886" }, { "database": "PubMed", "id": "18498745", "url": "https://pubmed.ncbi.nlm.nih.gov/18498745" } ], "site_lbl": "Ser307", "uniprot_canonical_ac": "P35568-1" } ], "record_id": "pubmed.16839860", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Turnover of the active fraction of IRS1 involves raptor-mTOR- and S6K1-dependent serine phosphorylation in cell culture models of tuberous sclerosis.", "journal": "Molecular and cellular biology", "date": "2006", "authors": "Shah OJ, Hunter T", "reference": { "type": "PubMed", "id": "16914728", "url": "https://pubmed.ncbi.nlm.nih.gov/16914728" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 527, "end_pos": 527, "kinase_uniprot_canonical_ac": "P23443-1", "kinase_gene_name": "RPS6KB1", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "16914728", "url": "https://pubmed.ncbi.nlm.nih.gov/16914728" } ], "site_lbl": "Ser527", "uniprot_canonical_ac": "P35568-1" } ], "record_id": "pubmed.16914728", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Long-term effects of tumor necrosis factor-alpha treatment on insulin signaling pathway in HepG2 cells and HepG2 cells overexpressing constitutively active Akt/PKB.", "journal": "Journal of cellular biochemistry", "date": "2007", "authors": "Gupta D, Varma S, Khandelwal RL", "reference": { "type": "PubMed", "id": "16960890", "url": "https://pubmed.ncbi.nlm.nih.gov/16960890" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 312, "end_pos": 312, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by IKKB, MAPK8 and RPS6KB1", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "12351658", "url": "https://pubmed.ncbi.nlm.nih.gov/12351658" }, { "database": "PubMed", "id": "12510059", "url": "https://pubmed.ncbi.nlm.nih.gov/12510059" }, { "database": "PubMed", "id": "14769130", "url": "https://pubmed.ncbi.nlm.nih.gov/14769130" }, { "database": "PubMed", "id": "15044323", "url": "https://pubmed.ncbi.nlm.nih.gov/15044323" }, { "database": "PubMed", "id": "15613682", "url": "https://pubmed.ncbi.nlm.nih.gov/15613682" }, { "database": "PubMed", "id": "15713122", "url": "https://pubmed.ncbi.nlm.nih.gov/15713122" }, { "database": "PubMed", "id": "15952059", "url": "https://pubmed.ncbi.nlm.nih.gov/15952059" }, { "database": "PubMed", "id": "16123357", "url": "https://pubmed.ncbi.nlm.nih.gov/16123357" }, { "database": "PubMed", "id": "16284649", "url": "https://pubmed.ncbi.nlm.nih.gov/16284649" }, { "database": "PubMed", "id": "16505239", "url": "https://pubmed.ncbi.nlm.nih.gov/16505239" }, { "database": "PubMed", "id": "16505244", "url": "https://pubmed.ncbi.nlm.nih.gov/16505244" }, { "database": "PubMed", "id": "16516141", "url": "https://pubmed.ncbi.nlm.nih.gov/16516141" }, { "database": "PubMed", "id": "16960890", "url": "https://pubmed.ncbi.nlm.nih.gov/16960890" }, { "database": "PubMed", "id": "17204522", "url": "https://pubmed.ncbi.nlm.nih.gov/17204522" }, { "database": "PubMed", "id": "17242212", "url": "https://pubmed.ncbi.nlm.nih.gov/17242212" }, { "database": "PubMed", "id": "17360977", "url": "https://pubmed.ncbi.nlm.nih.gov/17360977" }, { "database": "PubMed", "id": "17647275", "url": "https://pubmed.ncbi.nlm.nih.gov/17647275" }, { "database": "PubMed", "id": "18160431", "url": "https://pubmed.ncbi.nlm.nih.gov/18160431" }, { "database": "PubMed", "id": "19501568", "url": "https://pubmed.ncbi.nlm.nih.gov/19501568" }, { "database": "PubMed", "id": "19567513", "url": "https://pubmed.ncbi.nlm.nih.gov/19567513" }, { "database": "PubMed", "id": "19593406", "url": "https://pubmed.ncbi.nlm.nih.gov/19593406" }, { "database": "PubMed", "id": "20393162", "url": "https://pubmed.ncbi.nlm.nih.gov/20393162" }, { "database": "PubMed", "id": "20685959", "url": "https://pubmed.ncbi.nlm.nih.gov/20685959" }, { "database": "PubMed", "id": "20863384", "url": "https://pubmed.ncbi.nlm.nih.gov/20863384" }, { "database": "PubMed", "id": "21040800", "url": "https://pubmed.ncbi.nlm.nih.gov/21040800" }, { "database": "PubMed", "id": "21252690", "url": "https://pubmed.ncbi.nlm.nih.gov/21252690" }, { "database": "PubMed", "id": "21589939", "url": "https://pubmed.ncbi.nlm.nih.gov/21589939" }, { "database": "PubMed", "id": "21852229", "url": "https://pubmed.ncbi.nlm.nih.gov/21852229" }, { "database": "PubMed", "id": "21937042", "url": "https://pubmed.ncbi.nlm.nih.gov/21937042" }, { "database": "PubMed", "id": "22348058", "url": "https://pubmed.ncbi.nlm.nih.gov/22348058" }, { "database": "PubMed", "id": "22457223", "url": "https://pubmed.ncbi.nlm.nih.gov/22457223" }, { "database": "PubMed", "id": "22862962", "url": "https://pubmed.ncbi.nlm.nih.gov/22862962" }, { "database": "PubMed", "id": "25580119", "url": "https://pubmed.ncbi.nlm.nih.gov/25580119" }, { "database": "PubMed", "id": "27207509", "url": "https://pubmed.ncbi.nlm.nih.gov/27207509" }, { "database": "PubMed", "id": "27340831", "url": "https://pubmed.ncbi.nlm.nih.gov/27340831" }, { "database": "PubMed", "id": "32536688", "url": "https://pubmed.ncbi.nlm.nih.gov/32536688" }, { "database": "PubMed", "id": "33173197", "url": "https://pubmed.ncbi.nlm.nih.gov/33173197" }, { "database": "PubMed", "id": "35833836", "url": "https://pubmed.ncbi.nlm.nih.gov/35833836" }, { "database": "PubMed", "id": "18498745", "url": "https://pubmed.ncbi.nlm.nih.gov/18498745" } ], "site_lbl": "Ser312", "uniprot_canonical_ac": "P35568-1" } ], "record_id": "pubmed.16960890", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "PKCdelta-mediated IRS-1 Ser24 phosphorylation negatively regulates IRS-1 function.", "journal": "Biochemical and biophysical research communications", "date": "2006", "authors": "Greene MW, Ruhoff MS, Roth RA, Kim JA, Quon MJ, Krause JA", "reference": { "type": "PubMed", "id": "16970908", "url": "https://pubmed.ncbi.nlm.nih.gov/16970908" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 24, "end_pos": 24, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "16574739", "url": "https://pubmed.ncbi.nlm.nih.gov/16574739" }, { "database": "PubMed", "id": "16970908", "url": "https://pubmed.ncbi.nlm.nih.gov/16970908" }, { "database": "PubMed", "id": "25330241", "url": "https://pubmed.ncbi.nlm.nih.gov/25330241" } ], "site_lbl": "Ser24", "uniprot_canonical_ac": "P35568-1" } ], "record_id": "pubmed.16970908", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Interaction of FoxO1 and TSC2 induces insulin resistance through activation of the mammalian target of rapamycin/p70 S6K pathway.", "journal": "The Journal of biological chemistry", "date": "2006", "authors": "Cao Y, Kamioka Y, Yokoi N, Kobayashi T, Hino O, Onodera M, Mochizuki N, Nakae J", "reference": { "type": "PubMed", "id": "17077083", "url": "https://pubmed.ncbi.nlm.nih.gov/17077083" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 307, "end_pos": 307, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by RPS6KB1", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "11160134", "url": "https://pubmed.ncbi.nlm.nih.gov/11160134" }, { "database": "PubMed", "id": "11606564", "url": "https://pubmed.ncbi.nlm.nih.gov/11606564" }, { "database": "PubMed", "id": "12409308", "url": "https://pubmed.ncbi.nlm.nih.gov/12409308" }, { "database": "PubMed", "id": "12714600", "url": "https://pubmed.ncbi.nlm.nih.gov/12714600" }, { "database": "PubMed", "id": "12730242", "url": "https://pubmed.ncbi.nlm.nih.gov/12730242" }, { "database": "PubMed", "id": "14556646", "url": "https://pubmed.ncbi.nlm.nih.gov/14556646" }, { "database": "PubMed", "id": "14583092", "url": "https://pubmed.ncbi.nlm.nih.gov/14583092" }, { "database": "PubMed", "id": "14641015", "url": "https://pubmed.ncbi.nlm.nih.gov/14641015" }, { "database": "PubMed", "id": "14697666", "url": "https://pubmed.ncbi.nlm.nih.gov/14697666" }, { "database": "PubMed", "id": "15020250", "url": "https://pubmed.ncbi.nlm.nih.gov/15020250" }, { "database": "PubMed", "id": "15153564", "url": "https://pubmed.ncbi.nlm.nih.gov/15153564" }, { "database": "PubMed", "id": "15582605", "url": "https://pubmed.ncbi.nlm.nih.gov/15582605" }, { "database": "PubMed", "id": "15802620", "url": "https://pubmed.ncbi.nlm.nih.gov/15802620" }, { "database": "PubMed", "id": "16046301", "url": "https://pubmed.ncbi.nlm.nih.gov/16046301" }, { "database": "PubMed", "id": "16055440", "url": "https://pubmed.ncbi.nlm.nih.gov/16055440" }, { "database": "PubMed", "id": "16099428", "url": "https://pubmed.ncbi.nlm.nih.gov/16099428" }, { "database": "PubMed", "id": "16210322", "url": "https://pubmed.ncbi.nlm.nih.gov/16210322" }, { "database": "PubMed", "id": "16269459", "url": "https://pubmed.ncbi.nlm.nih.gov/16269459" }, { "database": "PubMed", "id": "16516141", "url": "https://pubmed.ncbi.nlm.nih.gov/16516141" }, { "database": "PubMed", "id": "16754954", "url": "https://pubmed.ncbi.nlm.nih.gov/16754954" }, { "database": "PubMed", "id": "16839860", "url": "https://pubmed.ncbi.nlm.nih.gov/16839860" }, { "database": "PubMed", "id": "17077083", "url": "https://pubmed.ncbi.nlm.nih.gov/17077083" }, { "database": "PubMed", "id": "17095576", "url": "https://pubmed.ncbi.nlm.nih.gov/17095576" }, { "database": "PubMed", "id": "17276034", "url": "https://pubmed.ncbi.nlm.nih.gov/17276034" }, { "database": "PubMed", "id": "17481767", "url": "https://pubmed.ncbi.nlm.nih.gov/17481767" }, { "database": "PubMed", "id": "17575262", "url": "https://pubmed.ncbi.nlm.nih.gov/17575262" }, { "database": "PubMed", "id": "18187553", "url": "https://pubmed.ncbi.nlm.nih.gov/18187553" }, { "database": "PubMed", "id": "18372392", "url": "https://pubmed.ncbi.nlm.nih.gov/18372392" }, { "database": "PubMed", "id": "18380932", "url": "https://pubmed.ncbi.nlm.nih.gov/18380932" }, { "database": "PubMed", "id": "18496818", "url": "https://pubmed.ncbi.nlm.nih.gov/18496818" }, { "database": "PubMed", "id": "18952604", "url": "https://pubmed.ncbi.nlm.nih.gov/18952604" }, { "database": "PubMed", "id": "19095745", "url": "https://pubmed.ncbi.nlm.nih.gov/19095745" }, { "database": "PubMed", "id": "19524129", "url": "https://pubmed.ncbi.nlm.nih.gov/19524129" }, { "database": "PubMed", "id": "19897715", "url": "https://pubmed.ncbi.nlm.nih.gov/19897715" }, { "database": "PubMed", "id": "20351777", "url": "https://pubmed.ncbi.nlm.nih.gov/20351777" }, { "database": "PubMed", "id": "20382011", "url": "https://pubmed.ncbi.nlm.nih.gov/20382011" }, { "database": "PubMed", "id": "20384568", "url": "https://pubmed.ncbi.nlm.nih.gov/20384568" }, { "database": "PubMed", "id": "20541543", "url": "https://pubmed.ncbi.nlm.nih.gov/20541543" }, { "database": "PubMed", "id": "20587749", "url": "https://pubmed.ncbi.nlm.nih.gov/20587749" }, { "database": "PubMed", "id": "20594161", "url": "https://pubmed.ncbi.nlm.nih.gov/20594161" }, { "database": "PubMed", "id": "20594757", "url": "https://pubmed.ncbi.nlm.nih.gov/20594757" }, { "database": "PubMed", "id": "20702573", "url": "https://pubmed.ncbi.nlm.nih.gov/20702573" }, { "database": "PubMed", "id": "21119656", "url": "https://pubmed.ncbi.nlm.nih.gov/21119656" }, { "database": "PubMed", "id": "21478152", "url": "https://pubmed.ncbi.nlm.nih.gov/21478152" }, { "database": "PubMed", "id": "21505982", "url": "https://pubmed.ncbi.nlm.nih.gov/21505982" }, { "database": "PubMed", "id": "21786209", "url": "https://pubmed.ncbi.nlm.nih.gov/21786209" }, { "database": "PubMed", "id": "21852229", "url": "https://pubmed.ncbi.nlm.nih.gov/21852229" }, { "database": "PubMed", "id": "21900690", "url": "https://pubmed.ncbi.nlm.nih.gov/21900690" }, { "database": "PubMed", "id": "22046423", "url": "https://pubmed.ncbi.nlm.nih.gov/22046423" }, { "database": "PubMed", "id": "22227580", "url": "https://pubmed.ncbi.nlm.nih.gov/22227580" }, { "database": "PubMed", "id": "22266116", "url": "https://pubmed.ncbi.nlm.nih.gov/22266116" }, { "database": "PubMed", "id": "22328823", "url": "https://pubmed.ncbi.nlm.nih.gov/22328823" }, { "database": "PubMed", "id": "22348058", "url": "https://pubmed.ncbi.nlm.nih.gov/22348058" }, { "database": "PubMed", "id": "22491740", "url": "https://pubmed.ncbi.nlm.nih.gov/22491740" }, { "database": "PubMed", "id": "22728372", "url": "https://pubmed.ncbi.nlm.nih.gov/22728372" }, { "database": "PubMed", "id": "22766331", "url": "https://pubmed.ncbi.nlm.nih.gov/22766331" }, { "database": "PubMed", "id": "23095254", "url": "https://pubmed.ncbi.nlm.nih.gov/23095254" }, { "database": "PubMed", "id": "23174405", "url": "https://pubmed.ncbi.nlm.nih.gov/23174405" }, { "database": "PubMed", "id": "23182460", "url": "https://pubmed.ncbi.nlm.nih.gov/23182460" }, { "database": "PubMed", "id": "23481042", "url": "https://pubmed.ncbi.nlm.nih.gov/23481042" }, { "database": "PubMed", "id": "23566306", "url": "https://pubmed.ncbi.nlm.nih.gov/23566306" }, { "database": "PubMed", "id": "23592917", "url": "https://pubmed.ncbi.nlm.nih.gov/23592917" }, { "database": "PubMed", "id": "23891856", "url": "https://pubmed.ncbi.nlm.nih.gov/23891856" }, { "database": "PubMed", "id": "23958494", "url": "https://pubmed.ncbi.nlm.nih.gov/23958494" }, { "database": "PubMed", "id": "24068326", "url": "https://pubmed.ncbi.nlm.nih.gov/24068326" }, { "database": "PubMed", "id": "24846082", "url": "https://pubmed.ncbi.nlm.nih.gov/24846082" }, { "database": "PubMed", "id": "25120613", "url": "https://pubmed.ncbi.nlm.nih.gov/25120613" }, { "database": "PubMed", "id": "25355439", "url": "https://pubmed.ncbi.nlm.nih.gov/25355439" }, { "database": "PubMed", "id": "25645159", "url": "https://pubmed.ncbi.nlm.nih.gov/25645159" }, { "database": "PubMed", "id": "25799226", "url": "https://pubmed.ncbi.nlm.nih.gov/25799226" }, { "database": "PubMed", "id": "26604643", "url": "https://pubmed.ncbi.nlm.nih.gov/26604643" }, { "database": "PubMed", "id": "26698173", "url": "https://pubmed.ncbi.nlm.nih.gov/26698173" }, { "database": "PubMed", "id": "26704265", "url": "https://pubmed.ncbi.nlm.nih.gov/26704265" }, { "database": "PubMed", "id": "26899161", "url": "https://pubmed.ncbi.nlm.nih.gov/26899161" }, { "database": "PubMed", "id": "26983645", "url": "https://pubmed.ncbi.nlm.nih.gov/26983645" }, { "database": "PubMed", "id": "27222060", "url": "https://pubmed.ncbi.nlm.nih.gov/27222060" }, { "database": "PubMed", "id": "27506476", "url": "https://pubmed.ncbi.nlm.nih.gov/27506476" }, { "database": "PubMed", "id": "27544192", "url": "https://pubmed.ncbi.nlm.nih.gov/27544192" }, { "database": "PubMed", "id": "27686967", "url": "https://pubmed.ncbi.nlm.nih.gov/27686967" }, { "database": "PubMed", "id": "27936435", "url": "https://pubmed.ncbi.nlm.nih.gov/27936435" }, { "database": "PubMed", "id": "28161417", "url": "https://pubmed.ncbi.nlm.nih.gov/28161417" }, { "database": "PubMed", "id": "28656239", "url": "https://pubmed.ncbi.nlm.nih.gov/28656239" }, { "database": "PubMed", "id": "28731188", "url": "https://pubmed.ncbi.nlm.nih.gov/28731188" }, { "database": "PubMed", "id": "28790390", "url": "https://pubmed.ncbi.nlm.nih.gov/28790390" }, { "database": "PubMed", "id": "28934129", "url": "https://pubmed.ncbi.nlm.nih.gov/28934129" }, { "database": "PubMed", "id": "29177868", "url": "https://pubmed.ncbi.nlm.nih.gov/29177868" }, { "database": "PubMed", "id": "29311680", "url": "https://pubmed.ncbi.nlm.nih.gov/29311680" }, { "database": "PubMed", "id": "29393871", "url": "https://pubmed.ncbi.nlm.nih.gov/29393871" }, { "database": "PubMed", "id": "29432553", "url": "https://pubmed.ncbi.nlm.nih.gov/29432553" }, { "database": "PubMed", "id": "29698741", "url": "https://pubmed.ncbi.nlm.nih.gov/29698741" }, { "database": "PubMed", "id": "29738527", "url": "https://pubmed.ncbi.nlm.nih.gov/29738527" }, { "database": "PubMed", "id": "30240640", "url": "https://pubmed.ncbi.nlm.nih.gov/30240640" }, { "database": "PubMed", "id": "30374127", "url": "https://pubmed.ncbi.nlm.nih.gov/30374127" }, { "database": "PubMed", "id": "30572687", "url": "https://pubmed.ncbi.nlm.nih.gov/30572687" }, { "database": "PubMed", "id": "31137828", "url": "https://pubmed.ncbi.nlm.nih.gov/31137828" }, { "database": "PubMed", "id": "31311314", "url": "https://pubmed.ncbi.nlm.nih.gov/31311314" }, { "database": "PubMed", "id": "31396538", "url": "https://pubmed.ncbi.nlm.nih.gov/31396538" }, { "database": "PubMed", "id": "32875583", "url": "https://pubmed.ncbi.nlm.nih.gov/32875583" }, { "database": "PubMed", "id": "33723215", "url": "https://pubmed.ncbi.nlm.nih.gov/33723215" }, { "database": "PubMed", "id": "35656886", "url": "https://pubmed.ncbi.nlm.nih.gov/35656886" }, { "database": "PubMed", "id": "18498745", "url": "https://pubmed.ncbi.nlm.nih.gov/18498745" } ], "site_lbl": "Ser307", "uniprot_canonical_ac": "P35568-1" } ], "record_id": "pubmed.17077083", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Amelioration of insulin resistance in women with PCOS via reduced insulin receptor substrate-1 Ser312 phosphorylation following laparoscopic ovarian electrocautery.", "journal": "Human reproduction (Oxford, England)", "date": "2007", "authors": "Seow KM, Juan CC, Hsu YP, Hwang JL, Huang LW, Ho LT", "reference": { "type": "PubMed", "id": "17204522", "url": "https://pubmed.ncbi.nlm.nih.gov/17204522" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 312, "end_pos": 312, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by IKKB, MAPK8 and RPS6KB1", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "12351658", "url": "https://pubmed.ncbi.nlm.nih.gov/12351658" }, { "database": "PubMed", "id": "12510059", "url": "https://pubmed.ncbi.nlm.nih.gov/12510059" }, { "database": "PubMed", "id": "14769130", "url": "https://pubmed.ncbi.nlm.nih.gov/14769130" }, { "database": "PubMed", "id": "15044323", "url": "https://pubmed.ncbi.nlm.nih.gov/15044323" }, { "database": "PubMed", "id": "15613682", "url": "https://pubmed.ncbi.nlm.nih.gov/15613682" }, { "database": "PubMed", "id": "15713122", "url": "https://pubmed.ncbi.nlm.nih.gov/15713122" }, { "database": "PubMed", "id": "15952059", "url": "https://pubmed.ncbi.nlm.nih.gov/15952059" }, { "database": "PubMed", "id": "16123357", "url": "https://pubmed.ncbi.nlm.nih.gov/16123357" }, { "database": "PubMed", "id": "16284649", "url": "https://pubmed.ncbi.nlm.nih.gov/16284649" }, { "database": "PubMed", "id": "16505239", "url": "https://pubmed.ncbi.nlm.nih.gov/16505239" }, { "database": "PubMed", "id": "16505244", "url": "https://pubmed.ncbi.nlm.nih.gov/16505244" }, { "database": "PubMed", "id": "16516141", "url": "https://pubmed.ncbi.nlm.nih.gov/16516141" }, { "database": "PubMed", "id": "16960890", "url": "https://pubmed.ncbi.nlm.nih.gov/16960890" }, { "database": "PubMed", "id": "17204522", "url": "https://pubmed.ncbi.nlm.nih.gov/17204522" }, { "database": "PubMed", "id": "17242212", "url": "https://pubmed.ncbi.nlm.nih.gov/17242212" }, { "database": "PubMed", "id": "17360977", "url": "https://pubmed.ncbi.nlm.nih.gov/17360977" }, { "database": "PubMed", "id": "17647275", "url": "https://pubmed.ncbi.nlm.nih.gov/17647275" }, { "database": "PubMed", "id": "18160431", "url": "https://pubmed.ncbi.nlm.nih.gov/18160431" }, { "database": "PubMed", "id": "19501568", "url": "https://pubmed.ncbi.nlm.nih.gov/19501568" }, { "database": "PubMed", "id": "19567513", "url": "https://pubmed.ncbi.nlm.nih.gov/19567513" }, { "database": "PubMed", "id": "19593406", "url": "https://pubmed.ncbi.nlm.nih.gov/19593406" }, { "database": "PubMed", "id": "20393162", "url": "https://pubmed.ncbi.nlm.nih.gov/20393162" }, { "database": "PubMed", "id": "20685959", "url": "https://pubmed.ncbi.nlm.nih.gov/20685959" }, { "database": "PubMed", "id": "20863384", "url": "https://pubmed.ncbi.nlm.nih.gov/20863384" }, { "database": "PubMed", "id": "21040800", "url": "https://pubmed.ncbi.nlm.nih.gov/21040800" }, { "database": "PubMed", "id": "21252690", "url": "https://pubmed.ncbi.nlm.nih.gov/21252690" }, { "database": "PubMed", "id": "21589939", "url": "https://pubmed.ncbi.nlm.nih.gov/21589939" }, { "database": "PubMed", "id": "21852229", "url": "https://pubmed.ncbi.nlm.nih.gov/21852229" }, { "database": "PubMed", "id": "21937042", "url": "https://pubmed.ncbi.nlm.nih.gov/21937042" }, { "database": "PubMed", "id": "22348058", "url": "https://pubmed.ncbi.nlm.nih.gov/22348058" }, { "database": "PubMed", "id": "22457223", "url": "https://pubmed.ncbi.nlm.nih.gov/22457223" }, { "database": "PubMed", "id": "22862962", "url": "https://pubmed.ncbi.nlm.nih.gov/22862962" }, { "database": "PubMed", "id": "25580119", "url": "https://pubmed.ncbi.nlm.nih.gov/25580119" }, { "database": "PubMed", "id": "27207509", "url": "https://pubmed.ncbi.nlm.nih.gov/27207509" }, { "database": "PubMed", "id": "27340831", "url": "https://pubmed.ncbi.nlm.nih.gov/27340831" }, { "database": "PubMed", "id": "32536688", "url": "https://pubmed.ncbi.nlm.nih.gov/32536688" }, { "database": "PubMed", "id": "33173197", "url": "https://pubmed.ncbi.nlm.nih.gov/33173197" }, { "database": "PubMed", "id": "35833836", "url": "https://pubmed.ncbi.nlm.nih.gov/35833836" }, { "database": "PubMed", "id": "18498745", "url": "https://pubmed.ncbi.nlm.nih.gov/18498745" } ], "site_lbl": "Ser312", "uniprot_canonical_ac": "P35568-1" } ], "record_id": "pubmed.17204522", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Interleukin-6 impairs the insulin signaling pathway, promoting production of nitric oxide in human umbilical vein endothelial cells.", "journal": "Molecular and cellular biology", "date": "2007", "authors": "Andreozzi F, Laratta E, Procopio C, Hribal ML, Sciacqua A, Perticone M, Miele C, Perticone F, Sesti G", "reference": { "type": "PubMed", "id": "17242212", "url": "https://pubmed.ncbi.nlm.nih.gov/17242212" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 312, "end_pos": 312, "kinase_uniprot_canonical_ac": "P28482-1", "kinase_gene_name": "MAPK1", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "17242212", "url": "https://pubmed.ncbi.nlm.nih.gov/17242212" } ], "site_lbl": "Ser312", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 312, "end_pos": 312, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by IKKB, MAPK8 and RPS6KB1", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "12351658", "url": "https://pubmed.ncbi.nlm.nih.gov/12351658" }, { "database": "PubMed", "id": "12510059", "url": "https://pubmed.ncbi.nlm.nih.gov/12510059" }, { "database": "PubMed", "id": "14769130", "url": "https://pubmed.ncbi.nlm.nih.gov/14769130" }, { "database": "PubMed", "id": "15044323", "url": "https://pubmed.ncbi.nlm.nih.gov/15044323" }, { "database": "PubMed", "id": "15613682", "url": "https://pubmed.ncbi.nlm.nih.gov/15613682" }, { "database": "PubMed", "id": "15713122", "url": "https://pubmed.ncbi.nlm.nih.gov/15713122" }, { "database": "PubMed", "id": "15952059", "url": "https://pubmed.ncbi.nlm.nih.gov/15952059" }, { "database": "PubMed", "id": "16123357", "url": "https://pubmed.ncbi.nlm.nih.gov/16123357" }, { "database": "PubMed", "id": "16284649", "url": "https://pubmed.ncbi.nlm.nih.gov/16284649" }, { "database": "PubMed", "id": "16505239", "url": "https://pubmed.ncbi.nlm.nih.gov/16505239" }, { "database": "PubMed", "id": "16505244", "url": "https://pubmed.ncbi.nlm.nih.gov/16505244" }, { "database": "PubMed", "id": "16516141", "url": "https://pubmed.ncbi.nlm.nih.gov/16516141" }, { "database": "PubMed", "id": "16960890", "url": "https://pubmed.ncbi.nlm.nih.gov/16960890" }, { "database": "PubMed", "id": "17204522", "url": "https://pubmed.ncbi.nlm.nih.gov/17204522" }, { "database": "PubMed", "id": "17242212", "url": "https://pubmed.ncbi.nlm.nih.gov/17242212" }, { "database": "PubMed", "id": "17360977", "url": "https://pubmed.ncbi.nlm.nih.gov/17360977" }, { "database": "PubMed", "id": "17647275", "url": "https://pubmed.ncbi.nlm.nih.gov/17647275" }, { "database": "PubMed", "id": "18160431", "url": "https://pubmed.ncbi.nlm.nih.gov/18160431" }, { "database": "PubMed", "id": "19501568", "url": "https://pubmed.ncbi.nlm.nih.gov/19501568" }, { "database": "PubMed", "id": "19567513", "url": "https://pubmed.ncbi.nlm.nih.gov/19567513" }, { "database": "PubMed", "id": "19593406", "url": "https://pubmed.ncbi.nlm.nih.gov/19593406" }, { "database": "PubMed", "id": "20393162", "url": "https://pubmed.ncbi.nlm.nih.gov/20393162" }, { "database": "PubMed", "id": "20685959", "url": "https://pubmed.ncbi.nlm.nih.gov/20685959" }, { "database": "PubMed", "id": "20863384", "url": "https://pubmed.ncbi.nlm.nih.gov/20863384" }, { "database": "PubMed", "id": "21040800", "url": "https://pubmed.ncbi.nlm.nih.gov/21040800" }, { "database": "PubMed", "id": "21252690", "url": "https://pubmed.ncbi.nlm.nih.gov/21252690" }, { "database": "PubMed", "id": "21589939", "url": "https://pubmed.ncbi.nlm.nih.gov/21589939" }, { "database": "PubMed", "id": "21852229", "url": "https://pubmed.ncbi.nlm.nih.gov/21852229" }, { "database": "PubMed", "id": "21937042", "url": "https://pubmed.ncbi.nlm.nih.gov/21937042" }, { "database": "PubMed", "id": "22348058", "url": "https://pubmed.ncbi.nlm.nih.gov/22348058" }, { "database": "PubMed", "id": "22457223", "url": "https://pubmed.ncbi.nlm.nih.gov/22457223" }, { "database": "PubMed", "id": "22862962", "url": "https://pubmed.ncbi.nlm.nih.gov/22862962" }, { "database": "PubMed", "id": "25580119", "url": "https://pubmed.ncbi.nlm.nih.gov/25580119" }, { "database": "PubMed", "id": "27207509", "url": "https://pubmed.ncbi.nlm.nih.gov/27207509" }, { "database": "PubMed", "id": "27340831", "url": "https://pubmed.ncbi.nlm.nih.gov/27340831" }, { "database": "PubMed", "id": "32536688", "url": "https://pubmed.ncbi.nlm.nih.gov/32536688" }, { "database": "PubMed", "id": "33173197", "url": "https://pubmed.ncbi.nlm.nih.gov/33173197" }, { "database": "PubMed", "id": "35833836", "url": "https://pubmed.ncbi.nlm.nih.gov/35833836" }, { "database": "PubMed", "id": "18498745", "url": "https://pubmed.ncbi.nlm.nih.gov/18498745" } ], "site_lbl": "Ser312", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 612, "end_pos": 612, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by INSR", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "12220227", "url": "https://pubmed.ncbi.nlm.nih.gov/12220227" }, { "database": "IntAct", "id": "P35568", "url": "https://www.ebi.ac.uk/intact/interactors/id:P35568*" }, { "database": "PubMed", "id": "16230374", "url": "https://pubmed.ncbi.nlm.nih.gov/16230374" }, { "database": "PubMed", "id": "11416002", "url": "https://pubmed.ncbi.nlm.nih.gov/11416002" }, { "database": "PRO", "id": "P35568", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=P35568" }, { "database": "PubMed", "id": "15044323", "url": "https://pubmed.ncbi.nlm.nih.gov/15044323" }, { "database": "PubMed", "id": "16188907", "url": "https://pubmed.ncbi.nlm.nih.gov/16188907" }, { "database": "PubMed", "id": "17242212", "url": "https://pubmed.ncbi.nlm.nih.gov/17242212" }, { "database": "PubMed", "id": "17902048", "url": "https://pubmed.ncbi.nlm.nih.gov/17902048" }, { "database": "PubMed", "id": "19762915", "url": "https://pubmed.ncbi.nlm.nih.gov/19762915" }, { "database": "PubMed", "id": "20150288", "url": "https://pubmed.ncbi.nlm.nih.gov/20150288" }, { "database": "PubMed", "id": "21829658", "url": "https://pubmed.ncbi.nlm.nih.gov/21829658" }, { "database": "PubMed", "id": "21939528", "url": "https://pubmed.ncbi.nlm.nih.gov/21939528" }, { "database": "PubMed", "id": "23360399", "url": "https://pubmed.ncbi.nlm.nih.gov/23360399" }, { "database": "PubMed", "id": "23460259", "url": "https://pubmed.ncbi.nlm.nih.gov/23460259" }, { "database": "PubMed", "id": "23688189", "url": "https://pubmed.ncbi.nlm.nih.gov/23688189" }, { "database": "PubMed", "id": "25302072", "url": "https://pubmed.ncbi.nlm.nih.gov/25302072" }, { "database": "PubMed", "id": "25886138", "url": "https://pubmed.ncbi.nlm.nih.gov/25886138" }, { "database": "PubMed", "id": "26297026", "url": "https://pubmed.ncbi.nlm.nih.gov/26297026" }, { "database": "PubMed", "id": "26874193", "url": "https://pubmed.ncbi.nlm.nih.gov/26874193" }, { "database": "PubMed", "id": "28161417", "url": "https://pubmed.ncbi.nlm.nih.gov/28161417" }, { "database": "PubMed", "id": "28345670", "url": "https://pubmed.ncbi.nlm.nih.gov/28345670" }, { "database": "PubMed", "id": "28414818", "url": "https://pubmed.ncbi.nlm.nih.gov/28414818" }, { "database": "PubMed", "id": "28934129", "url": "https://pubmed.ncbi.nlm.nih.gov/28934129" }, { "database": "PubMed", "id": "28955049", "url": "https://pubmed.ncbi.nlm.nih.gov/28955049" }, { "database": "PubMed", "id": "29259227", "url": "https://pubmed.ncbi.nlm.nih.gov/29259227" }, { "database": "PubMed", "id": "29486856", "url": "https://pubmed.ncbi.nlm.nih.gov/29486856" }, { "database": "PubMed", "id": "30092354", "url": "https://pubmed.ncbi.nlm.nih.gov/30092354" }, { "database": "PubMed", "id": "23401856", "url": "https://pubmed.ncbi.nlm.nih.gov/23401856" } ], "site_lbl": "Tyr612", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 616, "end_pos": 616, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "16354680", "url": "https://pubmed.ncbi.nlm.nih.gov/16354680" }, { "database": "PubMed", "id": "8626671", "url": "https://pubmed.ncbi.nlm.nih.gov/8626671" }, { "database": "PubMed", "id": "14769130", "url": "https://pubmed.ncbi.nlm.nih.gov/14769130" }, { "database": "PubMed", "id": "15044323", "url": "https://pubmed.ncbi.nlm.nih.gov/15044323" }, { "database": "PubMed", "id": "15713122", "url": "https://pubmed.ncbi.nlm.nih.gov/15713122" }, { "database": "PubMed", "id": "17242212", "url": "https://pubmed.ncbi.nlm.nih.gov/17242212" }, { "database": "PubMed", "id": "17360977", "url": "https://pubmed.ncbi.nlm.nih.gov/17360977" }, { "database": "PubMed", "id": "17640984", "url": "https://pubmed.ncbi.nlm.nih.gov/17640984" }, { "database": "PubMed", "id": "21937042", "url": "https://pubmed.ncbi.nlm.nih.gov/21937042" }, { "database": "PubMed", "id": "22476197", "url": "https://pubmed.ncbi.nlm.nih.gov/22476197" }, { "database": "PubMed", "id": "26297026", "url": "https://pubmed.ncbi.nlm.nih.gov/26297026" } ], "site_lbl": "Ser616", "uniprot_canonical_ac": "P35568-1" } ], "record_id": "pubmed.17242212", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 3 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "C-reactive protein induces phosphorylation of insulin receptor substrate-1 on Ser307 and Ser 612 in L6 myocytes, thereby impairing the insulin signalling pathway that promotes glucose transport.", "journal": "Diabetologia", "date": "2007", "authors": "D'Alessandris C, Lauro R, Presta I, Sesti G", "reference": { "type": "PubMed", "id": "17279354", "url": "https://pubmed.ncbi.nlm.nih.gov/17279354" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 632, "end_pos": 632, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by INSR", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "IntAct", "id": "P35568", "url": "https://www.ebi.ac.uk/intact/interactors/id:P35568*" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "11416002", "url": "https://pubmed.ncbi.nlm.nih.gov/11416002" }, { "database": "PubMed", "id": "7680095", "url": "https://pubmed.ncbi.nlm.nih.gov/7680095" }, { "database": "PubMed", "id": "7680644", "url": "https://pubmed.ncbi.nlm.nih.gov/7680644" }, { "database": "PubMed", "id": "8382612", "url": "https://pubmed.ncbi.nlm.nih.gov/8382612" }, { "database": "PubMed", "id": "15044323", "url": "https://pubmed.ncbi.nlm.nih.gov/15044323" }, { "database": "PubMed", "id": "17279354", "url": "https://pubmed.ncbi.nlm.nih.gov/17279354" }, { "database": "PubMed", "id": "17640984", "url": "https://pubmed.ncbi.nlm.nih.gov/17640984" }, { "database": "PubMed", "id": "22558377", "url": "https://pubmed.ncbi.nlm.nih.gov/22558377" }, { "database": "PubMed", "id": "23404947", "url": "https://pubmed.ncbi.nlm.nih.gov/23404947" }, { "database": "PubMed", "id": "26077338", "url": "https://pubmed.ncbi.nlm.nih.gov/26077338" }, { "database": "PubMed", "id": "28414818", "url": "https://pubmed.ncbi.nlm.nih.gov/28414818" }, { "database": "PubMed", "id": "28934129", "url": "https://pubmed.ncbi.nlm.nih.gov/28934129" }, { "database": "PubMed", "id": "29698741", "url": "https://pubmed.ncbi.nlm.nih.gov/29698741" }, { "database": "PubMed", "id": "30863203", "url": "https://pubmed.ncbi.nlm.nih.gov/30863203" }, { "database": "PubMed", "id": "31137828", "url": "https://pubmed.ncbi.nlm.nih.gov/31137828" }, { "database": "PubMed", "id": "31620609", "url": "https://pubmed.ncbi.nlm.nih.gov/31620609" }, { "database": "PubMed", "id": "23401856", "url": "https://pubmed.ncbi.nlm.nih.gov/23401856" } ], "site_lbl": "Tyr632", "uniprot_canonical_ac": "P35568-1" } ], "record_id": "pubmed.17279354", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Global assessment of regulation of phosphorylation of insulin receptor substrate-1 by insulin in vivo in human muscle.", "journal": "Diabetes", "date": "2007", "authors": "Yi Z, Langlais P, De Filippis EA, Luo M, Flynn CR, Schroeder S, Weintraub ST, Mapes R, Mandarino LJ", "reference": { "type": "PubMed", "id": "17360977", "url": "https://pubmed.ncbi.nlm.nih.gov/17360977" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 1005, "end_pos": 1005, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "17360977", "url": "https://pubmed.ncbi.nlm.nih.gov/17360977" } ], "site_lbl": "Ser1005", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 1100, "end_pos": 1100, "kinase_uniprot_canonical_ac": "P17612-1", "kinase_gene_name": "PRKACA", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "17360977", "url": "https://pubmed.ncbi.nlm.nih.gov/17360977" } ], "site_lbl": "Ser1100", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 1101, "end_pos": 1101, "kinase_uniprot_canonical_ac": "Q05513-1", "kinase_gene_name": "PRKCZ", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "17360977", "url": "https://pubmed.ncbi.nlm.nih.gov/17360977" } ], "site_lbl": "Ser1101", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 1101, "end_pos": 1101, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by RPS6KB1 and PKC/PRKCQ", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "15364919", "url": "https://pubmed.ncbi.nlm.nih.gov/15364919" }, { "database": "PubMed", "id": "17360977", "url": "https://pubmed.ncbi.nlm.nih.gov/17360977" }, { "database": "PubMed", "id": "17647275", "url": "https://pubmed.ncbi.nlm.nih.gov/17647275" }, { "database": "PubMed", "id": "17709744", "url": "https://pubmed.ncbi.nlm.nih.gov/17709744" }, { "database": "PubMed", "id": "18952604", "url": "https://pubmed.ncbi.nlm.nih.gov/18952604" }, { "database": "PubMed", "id": "20203102", "url": "https://pubmed.ncbi.nlm.nih.gov/20203102" }, { "database": "PubMed", "id": "22046423", "url": "https://pubmed.ncbi.nlm.nih.gov/22046423" }, { "database": "PubMed", "id": "24810050", "url": "https://pubmed.ncbi.nlm.nih.gov/24810050" }, { "database": "PubMed", "id": "24979806", "url": "https://pubmed.ncbi.nlm.nih.gov/24979806" }, { "database": "PubMed", "id": "25580119", "url": "https://pubmed.ncbi.nlm.nih.gov/25580119" }, { "database": "PubMed", "id": "26298773", "url": "https://pubmed.ncbi.nlm.nih.gov/26298773" }, { "database": "PubMed", "id": "28674284", "url": "https://pubmed.ncbi.nlm.nih.gov/28674284" }, { "database": "PubMed", "id": "28934129", "url": "https://pubmed.ncbi.nlm.nih.gov/28934129" }, { "database": "PubMed", "id": "29738527", "url": "https://pubmed.ncbi.nlm.nih.gov/29738527" }, { "database": "PubMed", "id": "30374127", "url": "https://pubmed.ncbi.nlm.nih.gov/30374127" }, { "database": "PubMed", "id": "32576196", "url": "https://pubmed.ncbi.nlm.nih.gov/32576196" } ], "site_lbl": "Ser1101", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 1222, "end_pos": 1222, "kinase_uniprot_canonical_ac": "P17612-1", "kinase_gene_name": "PRKACA", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "17360977", "url": "https://pubmed.ncbi.nlm.nih.gov/17360977" } ], "site_lbl": "Ser1222", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 1223, "end_pos": 1223, "kinase_uniprot_canonical_ac": "P17612-1", "kinase_gene_name": "PRKACA", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "17360977", "url": "https://pubmed.ncbi.nlm.nih.gov/17360977" } ], "site_lbl": "Ser1223", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 1223, "end_pos": 1223, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "16131083", "url": "https://pubmed.ncbi.nlm.nih.gov/16131083" }, { "database": "PubMed", "id": "16020478", "url": "https://pubmed.ncbi.nlm.nih.gov/16020478" }, { "database": "PubMed", "id": "17360977", "url": "https://pubmed.ncbi.nlm.nih.gov/17360977" } ], "site_lbl": "Ser1223", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 312, "end_pos": 312, "kinase_uniprot_canonical_ac": "O14733-1", "kinase_gene_name": "MAP2K7", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "17360977", "url": "https://pubmed.ncbi.nlm.nih.gov/17360977" } ], "site_lbl": "Ser312", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 312, "end_pos": 312, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by IKKB, MAPK8 and RPS6KB1", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "12351658", "url": "https://pubmed.ncbi.nlm.nih.gov/12351658" }, { "database": "PubMed", "id": "12510059", "url": "https://pubmed.ncbi.nlm.nih.gov/12510059" }, { "database": "PubMed", "id": "14769130", "url": "https://pubmed.ncbi.nlm.nih.gov/14769130" }, { "database": "PubMed", "id": "15044323", "url": "https://pubmed.ncbi.nlm.nih.gov/15044323" }, { "database": "PubMed", "id": "15613682", "url": "https://pubmed.ncbi.nlm.nih.gov/15613682" }, { "database": "PubMed", "id": "15713122", "url": "https://pubmed.ncbi.nlm.nih.gov/15713122" }, { "database": "PubMed", "id": "15952059", "url": "https://pubmed.ncbi.nlm.nih.gov/15952059" }, { "database": "PubMed", "id": "16123357", "url": "https://pubmed.ncbi.nlm.nih.gov/16123357" }, { "database": "PubMed", "id": "16284649", "url": "https://pubmed.ncbi.nlm.nih.gov/16284649" }, { "database": "PubMed", "id": "16505239", "url": "https://pubmed.ncbi.nlm.nih.gov/16505239" }, { "database": "PubMed", "id": "16505244", "url": "https://pubmed.ncbi.nlm.nih.gov/16505244" }, { "database": "PubMed", "id": "16516141", "url": "https://pubmed.ncbi.nlm.nih.gov/16516141" }, { "database": "PubMed", "id": "16960890", "url": "https://pubmed.ncbi.nlm.nih.gov/16960890" }, { "database": "PubMed", "id": "17204522", "url": "https://pubmed.ncbi.nlm.nih.gov/17204522" }, { "database": "PubMed", "id": "17242212", "url": "https://pubmed.ncbi.nlm.nih.gov/17242212" }, { "database": "PubMed", "id": "17360977", "url": "https://pubmed.ncbi.nlm.nih.gov/17360977" }, { "database": "PubMed", "id": "17647275", "url": "https://pubmed.ncbi.nlm.nih.gov/17647275" }, { "database": "PubMed", "id": "18160431", "url": "https://pubmed.ncbi.nlm.nih.gov/18160431" }, { "database": "PubMed", "id": "19501568", "url": "https://pubmed.ncbi.nlm.nih.gov/19501568" }, { "database": "PubMed", "id": "19567513", "url": "https://pubmed.ncbi.nlm.nih.gov/19567513" }, { "database": "PubMed", "id": "19593406", "url": "https://pubmed.ncbi.nlm.nih.gov/19593406" }, { "database": "PubMed", "id": "20393162", "url": "https://pubmed.ncbi.nlm.nih.gov/20393162" }, { "database": "PubMed", "id": "20685959", "url": "https://pubmed.ncbi.nlm.nih.gov/20685959" }, { "database": "PubMed", "id": "20863384", "url": "https://pubmed.ncbi.nlm.nih.gov/20863384" }, { "database": "PubMed", "id": "21040800", "url": "https://pubmed.ncbi.nlm.nih.gov/21040800" }, { "database": "PubMed", "id": "21252690", "url": "https://pubmed.ncbi.nlm.nih.gov/21252690" }, { "database": "PubMed", "id": "21589939", "url": "https://pubmed.ncbi.nlm.nih.gov/21589939" }, { "database": "PubMed", "id": "21852229", "url": "https://pubmed.ncbi.nlm.nih.gov/21852229" }, { "database": "PubMed", "id": "21937042", "url": "https://pubmed.ncbi.nlm.nih.gov/21937042" }, { "database": "PubMed", "id": "22348058", "url": "https://pubmed.ncbi.nlm.nih.gov/22348058" }, { "database": "PubMed", "id": "22457223", "url": "https://pubmed.ncbi.nlm.nih.gov/22457223" }, { "database": "PubMed", "id": "22862962", "url": "https://pubmed.ncbi.nlm.nih.gov/22862962" }, { "database": "PubMed", "id": "25580119", "url": "https://pubmed.ncbi.nlm.nih.gov/25580119" }, { "database": "PubMed", "id": "27207509", "url": "https://pubmed.ncbi.nlm.nih.gov/27207509" }, { "database": "PubMed", "id": "27340831", "url": "https://pubmed.ncbi.nlm.nih.gov/27340831" }, { "database": "PubMed", "id": "32536688", "url": "https://pubmed.ncbi.nlm.nih.gov/32536688" }, { "database": "PubMed", "id": "33173197", "url": "https://pubmed.ncbi.nlm.nih.gov/33173197" }, { "database": "PubMed", "id": "35833836", "url": "https://pubmed.ncbi.nlm.nih.gov/35833836" }, { "database": "PubMed", "id": "18498745", "url": "https://pubmed.ncbi.nlm.nih.gov/18498745" } ], "site_lbl": "Ser312", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 348, "end_pos": 348, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "PubMed", "id": "19690332", "url": "https://pubmed.ncbi.nlm.nih.gov/19690332" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "17360977", "url": "https://pubmed.ncbi.nlm.nih.gov/17360977" } ], "site_lbl": "Ser348", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 446, "end_pos": 446, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "17360977", "url": "https://pubmed.ncbi.nlm.nih.gov/17360977" } ], "site_lbl": "Thr446", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 495, "end_pos": 495, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "17360977", "url": "https://pubmed.ncbi.nlm.nih.gov/17360977" } ], "site_lbl": "Thr495", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 616, "end_pos": 616, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "16354680", "url": "https://pubmed.ncbi.nlm.nih.gov/16354680" }, { "database": "PubMed", "id": "8626671", "url": "https://pubmed.ncbi.nlm.nih.gov/8626671" }, { "database": "PubMed", "id": "14769130", "url": "https://pubmed.ncbi.nlm.nih.gov/14769130" }, { "database": "PubMed", "id": "15044323", "url": "https://pubmed.ncbi.nlm.nih.gov/15044323" }, { "database": "PubMed", "id": "15713122", "url": "https://pubmed.ncbi.nlm.nih.gov/15713122" }, { "database": "PubMed", "id": "17242212", "url": "https://pubmed.ncbi.nlm.nih.gov/17242212" }, { "database": "PubMed", "id": "17360977", "url": "https://pubmed.ncbi.nlm.nih.gov/17360977" }, { "database": "PubMed", "id": "17640984", "url": "https://pubmed.ncbi.nlm.nih.gov/17640984" }, { "database": "PubMed", "id": "21937042", "url": "https://pubmed.ncbi.nlm.nih.gov/21937042" }, { "database": "PubMed", "id": "22476197", "url": "https://pubmed.ncbi.nlm.nih.gov/22476197" }, { "database": "PubMed", "id": "26297026", "url": "https://pubmed.ncbi.nlm.nih.gov/26297026" } ], "site_lbl": "Ser616", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 636, "end_pos": 636, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by RPS6KB1", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "16131083", "url": "https://pubmed.ncbi.nlm.nih.gov/16131083" }, { "database": "PubMed", "id": "19651622", "url": "https://pubmed.ncbi.nlm.nih.gov/19651622" }, { "database": "PubMed", "id": "16354680", "url": "https://pubmed.ncbi.nlm.nih.gov/16354680" }, { "database": "PubMed", "id": "11287630", "url": "https://pubmed.ncbi.nlm.nih.gov/11287630" }, { "database": "PubMed", "id": "12765939", "url": "https://pubmed.ncbi.nlm.nih.gov/12765939" }, { "database": "PubMed", "id": "14769130", "url": "https://pubmed.ncbi.nlm.nih.gov/14769130" }, { "database": "PubMed", "id": "15576463", "url": "https://pubmed.ncbi.nlm.nih.gov/15576463" }, { "database": "PubMed", "id": "16123357", "url": "https://pubmed.ncbi.nlm.nih.gov/16123357" }, { "database": "PubMed", "id": "16284649", "url": "https://pubmed.ncbi.nlm.nih.gov/16284649" }, { "database": "PubMed", "id": "17360977", "url": "https://pubmed.ncbi.nlm.nih.gov/17360977" }, { "database": "PubMed", "id": "17640984", "url": "https://pubmed.ncbi.nlm.nih.gov/17640984" }, { "database": "PubMed", "id": "18597775", "url": "https://pubmed.ncbi.nlm.nih.gov/18597775" }, { "database": "PubMed", "id": "18952604", "url": "https://pubmed.ncbi.nlm.nih.gov/18952604" }, { "database": "PubMed", "id": "19561084", "url": "https://pubmed.ncbi.nlm.nih.gov/19561084" }, { "database": "PubMed", "id": "19581421", "url": "https://pubmed.ncbi.nlm.nih.gov/19581421" }, { "database": "PubMed", "id": "20203102", "url": "https://pubmed.ncbi.nlm.nih.gov/20203102" }, { "database": "PubMed", "id": "21478152", "url": "https://pubmed.ncbi.nlm.nih.gov/21478152" }, { "database": "PubMed", "id": "21829658", "url": "https://pubmed.ncbi.nlm.nih.gov/21829658" }, { "database": "PubMed", "id": "22348058", "url": "https://pubmed.ncbi.nlm.nih.gov/22348058" }, { "database": "PubMed", "id": "22966072", "url": "https://pubmed.ncbi.nlm.nih.gov/22966072" }, { "database": "PubMed", "id": "23512499", "url": "https://pubmed.ncbi.nlm.nih.gov/23512499" }, { "database": "PubMed", "id": "25667991", "url": "https://pubmed.ncbi.nlm.nih.gov/25667991" }, { "database": "PubMed", "id": "25799226", "url": "https://pubmed.ncbi.nlm.nih.gov/25799226" }, { "database": "PubMed", "id": "25813876", "url": "https://pubmed.ncbi.nlm.nih.gov/25813876" }, { "database": "PubMed", "id": "26077338", "url": "https://pubmed.ncbi.nlm.nih.gov/26077338" }, { "database": "PubMed", "id": "27434075", "url": "https://pubmed.ncbi.nlm.nih.gov/27434075" }, { "database": "PubMed", "id": "28652303", "url": "https://pubmed.ncbi.nlm.nih.gov/28652303" }, { "database": "PubMed", "id": "28934129", "url": "https://pubmed.ncbi.nlm.nih.gov/28934129" }, { "database": "PubMed", "id": "30381640", "url": "https://pubmed.ncbi.nlm.nih.gov/30381640" }, { "database": "PubMed", "id": "36111162", "url": "https://pubmed.ncbi.nlm.nih.gov/36111162" }, { "database": "PubMed", "id": "18498745", "url": "https://pubmed.ncbi.nlm.nih.gov/18498745" }, { "database": "PubMed", "id": "17081983", "url": "https://pubmed.ncbi.nlm.nih.gov/17081983" } ], "site_lbl": "Ser636", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 892, "end_pos": 892, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "17360977", "url": "https://pubmed.ncbi.nlm.nih.gov/17360977" } ], "site_lbl": "Ser892", "uniprot_canonical_ac": "P35568-1" } ], "record_id": "pubmed.17360977", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 15 }, { "field": "total_sites", "count": 12 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Energy depletion inhibits phosphatidylinositol 3-kinase/Akt signaling and induces apoptosis via AMP-activated protein kinase-dependent phosphorylation of IRS-1 at Ser-794.", "journal": "The Journal of biological chemistry", "date": "2007", "authors": "Tzatsos A, Tsichlis PN", "reference": { "type": "PubMed", "id": "17459875", "url": "https://pubmed.ncbi.nlm.nih.gov/17459875" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 794, "end_pos": 794, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by AMPK and SIK2", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "12006586", "url": "https://pubmed.ncbi.nlm.nih.gov/12006586" }, { "database": "PubMed", "id": "12624099", "url": "https://pubmed.ncbi.nlm.nih.gov/12624099" }, { "database": "PubMed", "id": "17459875", "url": "https://pubmed.ncbi.nlm.nih.gov/17459875" }, { "database": "PubMed", "id": "20363874", "url": "https://pubmed.ncbi.nlm.nih.gov/20363874" }, { "database": "PubMed", "id": "20863384", "url": "https://pubmed.ncbi.nlm.nih.gov/20863384" }, { "database": "PubMed", "id": "31446747", "url": "https://pubmed.ncbi.nlm.nih.gov/31446747" } ], "site_lbl": "Ser794", "uniprot_canonical_ac": "P35568-1" } ], "record_id": "pubmed.17459875", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Impact of mitochondrial ROS production in the pathogenesis of insulin resistance.", "journal": "Diabetes research and clinical practice", "date": "2007", "authors": "Nishikawa T, Kukidome D, Sonoda K, Fujisawa K, Matsuhisa T, Motoshima H, Matsumura T, Araki E", "reference": { "type": "PubMed", "id": "17481767", "url": "https://pubmed.ncbi.nlm.nih.gov/17481767" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 307, "end_pos": 307, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by RPS6KB1", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "11160134", "url": "https://pubmed.ncbi.nlm.nih.gov/11160134" }, { "database": "PubMed", "id": "11606564", "url": "https://pubmed.ncbi.nlm.nih.gov/11606564" }, { "database": "PubMed", "id": "12409308", "url": "https://pubmed.ncbi.nlm.nih.gov/12409308" }, { "database": "PubMed", "id": "12714600", "url": "https://pubmed.ncbi.nlm.nih.gov/12714600" }, { "database": "PubMed", "id": "12730242", "url": "https://pubmed.ncbi.nlm.nih.gov/12730242" }, { "database": "PubMed", "id": "14556646", "url": "https://pubmed.ncbi.nlm.nih.gov/14556646" }, { "database": "PubMed", "id": "14583092", "url": "https://pubmed.ncbi.nlm.nih.gov/14583092" }, { "database": "PubMed", "id": "14641015", "url": "https://pubmed.ncbi.nlm.nih.gov/14641015" }, { "database": "PubMed", "id": "14697666", "url": "https://pubmed.ncbi.nlm.nih.gov/14697666" }, { "database": "PubMed", "id": "15020250", "url": "https://pubmed.ncbi.nlm.nih.gov/15020250" }, { "database": "PubMed", "id": "15153564", "url": "https://pubmed.ncbi.nlm.nih.gov/15153564" }, { "database": "PubMed", "id": "15582605", "url": "https://pubmed.ncbi.nlm.nih.gov/15582605" }, { "database": "PubMed", "id": "15802620", "url": "https://pubmed.ncbi.nlm.nih.gov/15802620" }, { "database": "PubMed", "id": "16046301", "url": "https://pubmed.ncbi.nlm.nih.gov/16046301" }, { "database": "PubMed", "id": "16055440", "url": "https://pubmed.ncbi.nlm.nih.gov/16055440" }, { "database": "PubMed", "id": "16099428", "url": "https://pubmed.ncbi.nlm.nih.gov/16099428" }, { "database": "PubMed", "id": "16210322", "url": "https://pubmed.ncbi.nlm.nih.gov/16210322" }, { "database": "PubMed", "id": "16269459", "url": "https://pubmed.ncbi.nlm.nih.gov/16269459" }, { "database": "PubMed", "id": "16516141", "url": "https://pubmed.ncbi.nlm.nih.gov/16516141" }, { "database": "PubMed", "id": "16754954", "url": "https://pubmed.ncbi.nlm.nih.gov/16754954" }, { "database": "PubMed", "id": "16839860", "url": "https://pubmed.ncbi.nlm.nih.gov/16839860" }, { "database": "PubMed", "id": "17077083", "url": "https://pubmed.ncbi.nlm.nih.gov/17077083" }, { "database": "PubMed", "id": "17095576", "url": "https://pubmed.ncbi.nlm.nih.gov/17095576" }, { "database": "PubMed", "id": "17276034", "url": "https://pubmed.ncbi.nlm.nih.gov/17276034" }, { "database": "PubMed", "id": "17481767", "url": "https://pubmed.ncbi.nlm.nih.gov/17481767" }, { "database": "PubMed", "id": "17575262", "url": "https://pubmed.ncbi.nlm.nih.gov/17575262" }, { "database": "PubMed", "id": "18187553", "url": "https://pubmed.ncbi.nlm.nih.gov/18187553" }, { "database": "PubMed", "id": "18372392", "url": "https://pubmed.ncbi.nlm.nih.gov/18372392" }, { "database": "PubMed", "id": "18380932", "url": "https://pubmed.ncbi.nlm.nih.gov/18380932" }, { "database": "PubMed", "id": "18496818", "url": "https://pubmed.ncbi.nlm.nih.gov/18496818" }, { "database": "PubMed", "id": "18952604", "url": "https://pubmed.ncbi.nlm.nih.gov/18952604" }, { "database": "PubMed", "id": "19095745", "url": "https://pubmed.ncbi.nlm.nih.gov/19095745" }, { "database": "PubMed", "id": "19524129", "url": "https://pubmed.ncbi.nlm.nih.gov/19524129" }, { "database": "PubMed", "id": "19897715", "url": "https://pubmed.ncbi.nlm.nih.gov/19897715" }, { "database": "PubMed", "id": "20351777", "url": "https://pubmed.ncbi.nlm.nih.gov/20351777" }, { "database": "PubMed", "id": "20382011", "url": "https://pubmed.ncbi.nlm.nih.gov/20382011" }, { "database": "PubMed", "id": "20384568", "url": "https://pubmed.ncbi.nlm.nih.gov/20384568" }, { "database": "PubMed", "id": "20541543", "url": "https://pubmed.ncbi.nlm.nih.gov/20541543" }, { "database": "PubMed", "id": "20587749", "url": "https://pubmed.ncbi.nlm.nih.gov/20587749" }, { "database": "PubMed", "id": "20594161", "url": "https://pubmed.ncbi.nlm.nih.gov/20594161" }, { "database": "PubMed", "id": "20594757", "url": "https://pubmed.ncbi.nlm.nih.gov/20594757" }, { "database": "PubMed", "id": "20702573", "url": "https://pubmed.ncbi.nlm.nih.gov/20702573" }, { "database": "PubMed", "id": "21119656", "url": "https://pubmed.ncbi.nlm.nih.gov/21119656" }, { "database": "PubMed", "id": "21478152", "url": "https://pubmed.ncbi.nlm.nih.gov/21478152" }, { "database": "PubMed", "id": "21505982", "url": "https://pubmed.ncbi.nlm.nih.gov/21505982" }, { "database": "PubMed", "id": "21786209", "url": "https://pubmed.ncbi.nlm.nih.gov/21786209" }, { "database": "PubMed", "id": "21852229", "url": "https://pubmed.ncbi.nlm.nih.gov/21852229" }, { "database": "PubMed", "id": "21900690", "url": "https://pubmed.ncbi.nlm.nih.gov/21900690" }, { "database": "PubMed", "id": "22046423", "url": "https://pubmed.ncbi.nlm.nih.gov/22046423" }, { "database": "PubMed", "id": "22227580", "url": "https://pubmed.ncbi.nlm.nih.gov/22227580" }, { "database": "PubMed", "id": "22266116", "url": "https://pubmed.ncbi.nlm.nih.gov/22266116" }, { "database": "PubMed", "id": "22328823", "url": "https://pubmed.ncbi.nlm.nih.gov/22328823" }, { "database": "PubMed", "id": "22348058", "url": "https://pubmed.ncbi.nlm.nih.gov/22348058" }, { "database": "PubMed", "id": "22491740", "url": "https://pubmed.ncbi.nlm.nih.gov/22491740" }, { "database": "PubMed", "id": "22728372", "url": "https://pubmed.ncbi.nlm.nih.gov/22728372" }, { "database": "PubMed", "id": "22766331", "url": "https://pubmed.ncbi.nlm.nih.gov/22766331" }, { "database": "PubMed", "id": "23095254", "url": "https://pubmed.ncbi.nlm.nih.gov/23095254" }, { "database": "PubMed", "id": "23174405", "url": "https://pubmed.ncbi.nlm.nih.gov/23174405" }, { "database": "PubMed", "id": "23182460", "url": "https://pubmed.ncbi.nlm.nih.gov/23182460" }, { "database": "PubMed", "id": "23481042", "url": "https://pubmed.ncbi.nlm.nih.gov/23481042" }, { "database": "PubMed", "id": "23566306", "url": "https://pubmed.ncbi.nlm.nih.gov/23566306" }, { "database": "PubMed", "id": "23592917", "url": "https://pubmed.ncbi.nlm.nih.gov/23592917" }, { "database": "PubMed", "id": "23891856", "url": "https://pubmed.ncbi.nlm.nih.gov/23891856" }, { "database": "PubMed", "id": "23958494", "url": "https://pubmed.ncbi.nlm.nih.gov/23958494" }, { "database": "PubMed", "id": "24068326", "url": "https://pubmed.ncbi.nlm.nih.gov/24068326" }, { "database": "PubMed", "id": "24846082", "url": "https://pubmed.ncbi.nlm.nih.gov/24846082" }, { "database": "PubMed", "id": "25120613", "url": "https://pubmed.ncbi.nlm.nih.gov/25120613" }, { "database": "PubMed", "id": "25355439", "url": "https://pubmed.ncbi.nlm.nih.gov/25355439" }, { "database": "PubMed", "id": "25645159", "url": "https://pubmed.ncbi.nlm.nih.gov/25645159" }, { "database": "PubMed", "id": "25799226", "url": "https://pubmed.ncbi.nlm.nih.gov/25799226" }, { "database": "PubMed", "id": "26604643", "url": "https://pubmed.ncbi.nlm.nih.gov/26604643" }, { "database": "PubMed", "id": "26698173", "url": "https://pubmed.ncbi.nlm.nih.gov/26698173" }, { "database": "PubMed", "id": "26704265", "url": "https://pubmed.ncbi.nlm.nih.gov/26704265" }, { "database": "PubMed", "id": "26899161", "url": "https://pubmed.ncbi.nlm.nih.gov/26899161" }, { "database": "PubMed", "id": "26983645", "url": "https://pubmed.ncbi.nlm.nih.gov/26983645" }, { "database": "PubMed", "id": "27222060", "url": "https://pubmed.ncbi.nlm.nih.gov/27222060" }, { "database": "PubMed", "id": "27506476", "url": "https://pubmed.ncbi.nlm.nih.gov/27506476" }, { "database": "PubMed", "id": "27544192", "url": "https://pubmed.ncbi.nlm.nih.gov/27544192" }, { "database": "PubMed", "id": "27686967", "url": "https://pubmed.ncbi.nlm.nih.gov/27686967" }, { "database": "PubMed", "id": "27936435", "url": "https://pubmed.ncbi.nlm.nih.gov/27936435" }, { "database": "PubMed", "id": "28161417", "url": "https://pubmed.ncbi.nlm.nih.gov/28161417" }, { "database": "PubMed", "id": "28656239", "url": "https://pubmed.ncbi.nlm.nih.gov/28656239" }, { "database": "PubMed", "id": "28731188", "url": "https://pubmed.ncbi.nlm.nih.gov/28731188" }, { "database": "PubMed", "id": "28790390", "url": "https://pubmed.ncbi.nlm.nih.gov/28790390" }, { "database": "PubMed", "id": "28934129", "url": "https://pubmed.ncbi.nlm.nih.gov/28934129" }, { "database": "PubMed", "id": "29177868", "url": "https://pubmed.ncbi.nlm.nih.gov/29177868" }, { "database": "PubMed", "id": "29311680", "url": "https://pubmed.ncbi.nlm.nih.gov/29311680" }, { "database": "PubMed", "id": "29393871", "url": "https://pubmed.ncbi.nlm.nih.gov/29393871" }, { "database": "PubMed", "id": "29432553", "url": "https://pubmed.ncbi.nlm.nih.gov/29432553" }, { "database": "PubMed", "id": "29698741", "url": "https://pubmed.ncbi.nlm.nih.gov/29698741" }, { "database": "PubMed", "id": "29738527", "url": "https://pubmed.ncbi.nlm.nih.gov/29738527" }, { "database": "PubMed", "id": "30240640", "url": "https://pubmed.ncbi.nlm.nih.gov/30240640" }, { "database": "PubMed", "id": "30374127", "url": "https://pubmed.ncbi.nlm.nih.gov/30374127" }, { "database": "PubMed", "id": "30572687", "url": "https://pubmed.ncbi.nlm.nih.gov/30572687" }, { "database": "PubMed", "id": "31137828", "url": "https://pubmed.ncbi.nlm.nih.gov/31137828" }, { "database": "PubMed", "id": "31311314", "url": "https://pubmed.ncbi.nlm.nih.gov/31311314" }, { "database": "PubMed", "id": "31396538", "url": "https://pubmed.ncbi.nlm.nih.gov/31396538" }, { "database": "PubMed", "id": "32875583", "url": "https://pubmed.ncbi.nlm.nih.gov/32875583" }, { "database": "PubMed", "id": "33723215", "url": "https://pubmed.ncbi.nlm.nih.gov/33723215" }, { "database": "PubMed", "id": "35656886", "url": "https://pubmed.ncbi.nlm.nih.gov/35656886" }, { "database": "PubMed", "id": "18498745", "url": "https://pubmed.ncbi.nlm.nih.gov/18498745" } ], "site_lbl": "Ser307", "uniprot_canonical_ac": "P35568-1" } ], "record_id": "pubmed.17481767", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Secretion of atherogenic risk factor apolipoprotein B-100 is increased by a potential mechanism of JNK/PKC-mediated insulin resistance in liver cells.", "journal": "Journal of cellular biochemistry", "date": "2008", "authors": "Jin UH, Kang YJ, Chang YC, Kim CH", "reference": { "type": "PubMed", "id": "17647275", "url": "https://pubmed.ncbi.nlm.nih.gov/17647275" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 1101, "end_pos": 1101, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by RPS6KB1 and PKC/PRKCQ", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "15364919", "url": "https://pubmed.ncbi.nlm.nih.gov/15364919" }, { "database": "PubMed", "id": "17360977", "url": "https://pubmed.ncbi.nlm.nih.gov/17360977" }, { "database": "PubMed", "id": "17647275", "url": "https://pubmed.ncbi.nlm.nih.gov/17647275" }, { "database": "PubMed", "id": "17709744", "url": "https://pubmed.ncbi.nlm.nih.gov/17709744" }, { "database": "PubMed", "id": "18952604", "url": "https://pubmed.ncbi.nlm.nih.gov/18952604" }, { "database": "PubMed", "id": "20203102", "url": "https://pubmed.ncbi.nlm.nih.gov/20203102" }, { "database": "PubMed", "id": "22046423", "url": "https://pubmed.ncbi.nlm.nih.gov/22046423" }, { "database": "PubMed", "id": "24810050", "url": "https://pubmed.ncbi.nlm.nih.gov/24810050" }, { "database": "PubMed", "id": "24979806", "url": "https://pubmed.ncbi.nlm.nih.gov/24979806" }, { "database": "PubMed", "id": "25580119", "url": "https://pubmed.ncbi.nlm.nih.gov/25580119" }, { "database": "PubMed", "id": "26298773", "url": "https://pubmed.ncbi.nlm.nih.gov/26298773" }, { "database": "PubMed", "id": "28674284", "url": "https://pubmed.ncbi.nlm.nih.gov/28674284" }, { "database": "PubMed", "id": "28934129", "url": "https://pubmed.ncbi.nlm.nih.gov/28934129" }, { "database": "PubMed", "id": "29738527", "url": "https://pubmed.ncbi.nlm.nih.gov/29738527" }, { "database": "PubMed", "id": "30374127", "url": "https://pubmed.ncbi.nlm.nih.gov/30374127" }, { "database": "PubMed", "id": "32576196", "url": "https://pubmed.ncbi.nlm.nih.gov/32576196" } ], "site_lbl": "Ser1101", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 312, "end_pos": 312, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by IKKB, MAPK8 and RPS6KB1", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "12351658", "url": "https://pubmed.ncbi.nlm.nih.gov/12351658" }, { "database": "PubMed", "id": "12510059", "url": "https://pubmed.ncbi.nlm.nih.gov/12510059" }, { "database": "PubMed", "id": "14769130", "url": "https://pubmed.ncbi.nlm.nih.gov/14769130" }, { "database": "PubMed", "id": "15044323", "url": "https://pubmed.ncbi.nlm.nih.gov/15044323" }, { "database": "PubMed", "id": "15613682", "url": "https://pubmed.ncbi.nlm.nih.gov/15613682" }, { "database": "PubMed", "id": "15713122", "url": "https://pubmed.ncbi.nlm.nih.gov/15713122" }, { "database": "PubMed", "id": "15952059", "url": "https://pubmed.ncbi.nlm.nih.gov/15952059" }, { "database": "PubMed", "id": "16123357", "url": "https://pubmed.ncbi.nlm.nih.gov/16123357" }, { "database": "PubMed", "id": "16284649", "url": "https://pubmed.ncbi.nlm.nih.gov/16284649" }, { "database": "PubMed", "id": "16505239", "url": "https://pubmed.ncbi.nlm.nih.gov/16505239" }, { "database": "PubMed", "id": "16505244", "url": "https://pubmed.ncbi.nlm.nih.gov/16505244" }, { "database": "PubMed", "id": "16516141", "url": "https://pubmed.ncbi.nlm.nih.gov/16516141" }, { "database": "PubMed", "id": "16960890", "url": "https://pubmed.ncbi.nlm.nih.gov/16960890" }, { "database": "PubMed", "id": "17204522", "url": "https://pubmed.ncbi.nlm.nih.gov/17204522" }, { "database": "PubMed", "id": "17242212", "url": "https://pubmed.ncbi.nlm.nih.gov/17242212" }, { "database": "PubMed", "id": "17360977", "url": "https://pubmed.ncbi.nlm.nih.gov/17360977" }, { "database": "PubMed", "id": "17647275", "url": "https://pubmed.ncbi.nlm.nih.gov/17647275" }, { "database": "PubMed", "id": "18160431", "url": "https://pubmed.ncbi.nlm.nih.gov/18160431" }, { "database": "PubMed", "id": "19501568", "url": "https://pubmed.ncbi.nlm.nih.gov/19501568" }, { "database": "PubMed", "id": "19567513", "url": "https://pubmed.ncbi.nlm.nih.gov/19567513" }, { "database": "PubMed", "id": "19593406", "url": "https://pubmed.ncbi.nlm.nih.gov/19593406" }, { "database": "PubMed", "id": "20393162", "url": "https://pubmed.ncbi.nlm.nih.gov/20393162" }, { "database": "PubMed", "id": "20685959", "url": "https://pubmed.ncbi.nlm.nih.gov/20685959" }, { "database": "PubMed", "id": "20863384", "url": "https://pubmed.ncbi.nlm.nih.gov/20863384" }, { "database": "PubMed", "id": "21040800", "url": "https://pubmed.ncbi.nlm.nih.gov/21040800" }, { "database": "PubMed", "id": "21252690", "url": "https://pubmed.ncbi.nlm.nih.gov/21252690" }, { "database": "PubMed", "id": "21589939", "url": "https://pubmed.ncbi.nlm.nih.gov/21589939" }, { "database": "PubMed", "id": "21852229", "url": "https://pubmed.ncbi.nlm.nih.gov/21852229" }, { "database": "PubMed", "id": "21937042", "url": "https://pubmed.ncbi.nlm.nih.gov/21937042" }, { "database": "PubMed", "id": "22348058", "url": "https://pubmed.ncbi.nlm.nih.gov/22348058" }, { "database": "PubMed", "id": "22457223", "url": "https://pubmed.ncbi.nlm.nih.gov/22457223" }, { "database": "PubMed", "id": "22862962", "url": "https://pubmed.ncbi.nlm.nih.gov/22862962" }, { "database": "PubMed", "id": "25580119", "url": "https://pubmed.ncbi.nlm.nih.gov/25580119" }, { "database": "PubMed", "id": "27207509", "url": "https://pubmed.ncbi.nlm.nih.gov/27207509" }, { "database": "PubMed", "id": "27340831", "url": "https://pubmed.ncbi.nlm.nih.gov/27340831" }, { "database": "PubMed", "id": "32536688", "url": "https://pubmed.ncbi.nlm.nih.gov/32536688" }, { "database": "PubMed", "id": "33173197", "url": "https://pubmed.ncbi.nlm.nih.gov/33173197" }, { "database": "PubMed", "id": "35833836", "url": "https://pubmed.ncbi.nlm.nih.gov/35833836" }, { "database": "PubMed", "id": "18498745", "url": "https://pubmed.ncbi.nlm.nih.gov/18498745" } ], "site_lbl": "Ser312", "uniprot_canonical_ac": "P35568-1" } ], "record_id": "pubmed.17647275", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Insulin-like growth factor-1 potentiates platelet activation via the IRS/PI3Kalpha pathway.", "journal": "Blood", "date": "2007", "authors": "Hers I", "reference": { "type": "PubMed", "id": "17827393", "url": "https://pubmed.ncbi.nlm.nih.gov/17827393" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 1179, "end_pos": 1179, "kinase_uniprot_canonical_ac": "P08069-1", "kinase_gene_name": "IGF1R", "residue": "Tyr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "17827393", "url": "https://pubmed.ncbi.nlm.nih.gov/17827393" } ], "site_lbl": "Tyr1179", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 1229, "end_pos": 1229, "kinase_uniprot_canonical_ac": "P08069-1", "kinase_gene_name": "IGF1R", "residue": "Tyr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "17827393", "url": "https://pubmed.ncbi.nlm.nih.gov/17827393" } ], "site_lbl": "Tyr1229", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 465, "end_pos": 465, "kinase_uniprot_canonical_ac": "P08069-1", "kinase_gene_name": "IGF1R", "residue": "Tyr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "17827393", "url": "https://pubmed.ncbi.nlm.nih.gov/17827393" } ], "site_lbl": "Tyr465", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 612, "end_pos": 612, "kinase_uniprot_canonical_ac": "P08069-1", "kinase_gene_name": "IGF1R", "residue": "Tyr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "17827393", "url": "https://pubmed.ncbi.nlm.nih.gov/17827393" } ], "site_lbl": "Tyr612", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 632, "end_pos": 632, "kinase_uniprot_canonical_ac": "P08069-1", "kinase_gene_name": "IGF1R", "residue": "Tyr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "17827393", "url": "https://pubmed.ncbi.nlm.nih.gov/17827393" } ], "site_lbl": "Tyr632", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 896, "end_pos": 896, "kinase_uniprot_canonical_ac": "P08069-1", "kinase_gene_name": "IGF1R", "residue": "Tyr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "8530377", "url": "https://pubmed.ncbi.nlm.nih.gov/8530377" }, { "database": "PubMed", "id": "17827393", "url": "https://pubmed.ncbi.nlm.nih.gov/17827393" } ], "site_lbl": "Tyr896", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 941, "end_pos": 941, "kinase_uniprot_canonical_ac": "P08069-1", "kinase_gene_name": "IGF1R", "residue": "Tyr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "17827393", "url": "https://pubmed.ncbi.nlm.nih.gov/17827393" } ], "site_lbl": "Tyr941", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 989, "end_pos": 989, "kinase_uniprot_canonical_ac": "P08069-1", "kinase_gene_name": "IGF1R", "residue": "Tyr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "17827393", "url": "https://pubmed.ncbi.nlm.nih.gov/17827393" } ], "site_lbl": "Tyr989", "uniprot_canonical_ac": "P35568-1" } ], "record_id": "pubmed.17827393", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 8 }, { "field": "total_sites", "count": 8 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Insulin receptor substrate-1 involvement in epidermal growth factor receptor and insulin-like growth factor receptor signalling: implication for Gefitinib ('Iressa') response and resistance.", "journal": "Breast cancer research and treatment", "date": "2008", "authors": "Knowlden JM, Jones HE, Barrow D, Gee JM, Nicholson RI, Hutcheson IR", "reference": { "type": "PubMed", "id": "17902048", "url": "https://pubmed.ncbi.nlm.nih.gov/17902048" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 612, "end_pos": 612, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by INSR", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "12220227", "url": "https://pubmed.ncbi.nlm.nih.gov/12220227" }, { "database": "IntAct", "id": "P35568", "url": "https://www.ebi.ac.uk/intact/interactors/id:P35568*" }, { "database": "PubMed", "id": "16230374", "url": "https://pubmed.ncbi.nlm.nih.gov/16230374" }, { "database": "PubMed", "id": "11416002", "url": "https://pubmed.ncbi.nlm.nih.gov/11416002" }, { "database": "PRO", "id": "P35568", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=P35568" }, { "database": "PubMed", "id": "15044323", "url": "https://pubmed.ncbi.nlm.nih.gov/15044323" }, { "database": "PubMed", "id": "16188907", "url": "https://pubmed.ncbi.nlm.nih.gov/16188907" }, { "database": "PubMed", "id": "17242212", "url": "https://pubmed.ncbi.nlm.nih.gov/17242212" }, { "database": "PubMed", "id": "17902048", "url": "https://pubmed.ncbi.nlm.nih.gov/17902048" }, { "database": "PubMed", "id": "19762915", "url": "https://pubmed.ncbi.nlm.nih.gov/19762915" }, { "database": "PubMed", "id": "20150288", "url": "https://pubmed.ncbi.nlm.nih.gov/20150288" }, { "database": "PubMed", "id": "21829658", "url": "https://pubmed.ncbi.nlm.nih.gov/21829658" }, { "database": "PubMed", "id": "21939528", "url": "https://pubmed.ncbi.nlm.nih.gov/21939528" }, { "database": "PubMed", "id": "23360399", "url": "https://pubmed.ncbi.nlm.nih.gov/23360399" }, { "database": "PubMed", "id": "23460259", "url": "https://pubmed.ncbi.nlm.nih.gov/23460259" }, { "database": "PubMed", "id": "23688189", "url": "https://pubmed.ncbi.nlm.nih.gov/23688189" }, { "database": "PubMed", "id": "25302072", "url": "https://pubmed.ncbi.nlm.nih.gov/25302072" }, { "database": "PubMed", "id": "25886138", "url": "https://pubmed.ncbi.nlm.nih.gov/25886138" }, { "database": "PubMed", "id": "26297026", "url": "https://pubmed.ncbi.nlm.nih.gov/26297026" }, { "database": "PubMed", "id": "26874193", "url": "https://pubmed.ncbi.nlm.nih.gov/26874193" }, { "database": "PubMed", "id": "28161417", "url": "https://pubmed.ncbi.nlm.nih.gov/28161417" }, { "database": "PubMed", "id": "28345670", "url": "https://pubmed.ncbi.nlm.nih.gov/28345670" }, { "database": "PubMed", "id": "28414818", "url": "https://pubmed.ncbi.nlm.nih.gov/28414818" }, { "database": "PubMed", "id": "28934129", "url": "https://pubmed.ncbi.nlm.nih.gov/28934129" }, { "database": "PubMed", "id": "28955049", "url": "https://pubmed.ncbi.nlm.nih.gov/28955049" }, { "database": "PubMed", "id": "29259227", "url": "https://pubmed.ncbi.nlm.nih.gov/29259227" }, { "database": "PubMed", "id": "29486856", "url": "https://pubmed.ncbi.nlm.nih.gov/29486856" }, { "database": "PubMed", "id": "30092354", "url": "https://pubmed.ncbi.nlm.nih.gov/30092354" }, { "database": "PubMed", "id": "23401856", "url": "https://pubmed.ncbi.nlm.nih.gov/23401856" } ], "site_lbl": "Tyr612", "uniprot_canonical_ac": "P35568-1" }, { "start_pos": 896, "end_pos": 896, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by INSR", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "12220227", "url": "https://pubmed.ncbi.nlm.nih.gov/12220227" }, { "database": "IntAct", "id": "P35568", "url": "https://www.ebi.ac.uk/intact/interactors/id:P35568*" }, { "database": "PubMed", "id": "7513703", "url": "https://pubmed.ncbi.nlm.nih.gov/7513703" }, { "database": "PRO", "id": "P35568", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=P35568" }, { "database": "PubMed", "id": "17902048", "url": "https://pubmed.ncbi.nlm.nih.gov/17902048" }, { "database": "PubMed", "id": "21939528", "url": "https://pubmed.ncbi.nlm.nih.gov/21939528" }, { "database": "PubMed", "id": "23983791", "url": "https://pubmed.ncbi.nlm.nih.gov/23983791" }, { "database": "PubMed", "id": "25886138", "url": "https://pubmed.ncbi.nlm.nih.gov/25886138" }, { "database": "PubMed", "id": "31620609", "url": "https://pubmed.ncbi.nlm.nih.gov/31620609" }, { "database": "PubMed", "id": "23401856", "url": "https://pubmed.ncbi.nlm.nih.gov/23401856" } ], "site_lbl": "Tyr896", "uniprot_canonical_ac": "P35568-1" } ], "record_id": "pubmed.17902048", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Hepatitis C virus core protein upregulates serine phosphorylation of insulin receptor substrate-1 and impairs the downstream akt/protein kinase B signaling pathway for insulin resistance.", "journal": "Journal of virology", "date": "2008", "authors": "Banerjee S, Saito K, Ait-Goughoulte M, Meyer K, Ray RB, Ray R", "reference": { "type": "PubMed", "id": "18160431", "url": "https://pubmed.ncbi.nlm.nih.gov/18160431" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 312, "end_pos": 312, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by IKKB, MAPK8 and RPS6KB1", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "12351658", "url": "https://pubmed.ncbi.nlm.nih.gov/12351658" }, { "database": "PubMed", "id": "12510059", "url": "https://pubmed.ncbi.nlm.nih.gov/12510059" }, { "database": "PubMed", "id": "14769130", "url": "https://pubmed.ncbi.nlm.nih.gov/14769130" }, { "database": "PubMed", "id": "15044323", "url": "https://pubmed.ncbi.nlm.nih.gov/15044323" }, { "database": "PubMed", "id": "15613682", "url": "https://pubmed.ncbi.nlm.nih.gov/15613682" }, { "database": "PubMed", "id": "15713122", "url": "https://pubmed.ncbi.nlm.nih.gov/15713122" }, { "database": "PubMed", "id": "15952059", "url": "https://pubmed.ncbi.nlm.nih.gov/15952059" }, { "database": "PubMed", "id": "16123357", "url": "https://pubmed.ncbi.nlm.nih.gov/16123357" }, { "database": "PubMed", "id": "16284649", "url": "https://pubmed.ncbi.nlm.nih.gov/16284649" }, { "database": "PubMed", "id": "16505239", "url": "https://pubmed.ncbi.nlm.nih.gov/16505239" }, { "database": "PubMed", "id": "16505244", "url": "https://pubmed.ncbi.nlm.nih.gov/16505244" }, { "database": "PubMed", "id": "16516141", "url": "https://pubmed.ncbi.nlm.nih.gov/16516141" }, { "database": "PubMed", "id": "16960890", "url": "https://pubmed.ncbi.nlm.nih.gov/16960890" }, { "database": "PubMed", "id": "17204522", "url": "https://pubmed.ncbi.nlm.nih.gov/17204522" }, { "database": "PubMed", "id": "17242212", "url": "https://pubmed.ncbi.nlm.nih.gov/17242212" }, { "database": "PubMed", "id": "17360977", "url": "https://pubmed.ncbi.nlm.nih.gov/17360977" }, { "database": "PubMed", "id": "17647275", "url": "https://pubmed.ncbi.nlm.nih.gov/17647275" }, { "database": "PubMed", "id": "18160431", "url": "https://pubmed.ncbi.nlm.nih.gov/18160431" }, { "database": "PubMed", "id": "19501568", "url": "https://pubmed.ncbi.nlm.nih.gov/19501568" }, { "database": "PubMed", "id": "19567513", "url": "https://pubmed.ncbi.nlm.nih.gov/19567513" }, { "database": "PubMed", "id": "19593406", "url": "https://pubmed.ncbi.nlm.nih.gov/19593406" }, { "database": "PubMed", "id": "20393162", "url": "https://pubmed.ncbi.nlm.nih.gov/20393162" }, { "database": "PubMed", "id": "20685959", "url": "https://pubmed.ncbi.nlm.nih.gov/20685959" }, { "database": "PubMed", "id": "20863384", "url": "https://pubmed.ncbi.nlm.nih.gov/20863384" }, { "database": "PubMed", "id": "21040800", "url": "https://pubmed.ncbi.nlm.nih.gov/21040800" }, { "database": "PubMed", "id": "21252690", "url": "https://pubmed.ncbi.nlm.nih.gov/21252690" }, { "database": "PubMed", "id": "21589939", "url": "https://pubmed.ncbi.nlm.nih.gov/21589939" }, { "database": "PubMed", "id": "21852229", "url": "https://pubmed.ncbi.nlm.nih.gov/21852229" }, { "database": "PubMed", "id": "21937042", "url": "https://pubmed.ncbi.nlm.nih.gov/21937042" }, { "database": "PubMed", "id": "22348058", "url": "https://pubmed.ncbi.nlm.nih.gov/22348058" }, { "database": "PubMed", "id": "22457223", "url": "https://pubmed.ncbi.nlm.nih.gov/22457223" }, { "database": "PubMed", "id": "22862962", "url": "https://pubmed.ncbi.nlm.nih.gov/22862962" }, { "database": "PubMed", "id": "25580119", "url": "https://pubmed.ncbi.nlm.nih.gov/25580119" }, { "database": "PubMed", "id": "27207509", "url": "https://pubmed.ncbi.nlm.nih.gov/27207509" }, { "database": "PubMed", "id": "27340831", "url": "https://pubmed.ncbi.nlm.nih.gov/27340831" }, { "database": "PubMed", "id": "32536688", "url": "https://pubmed.ncbi.nlm.nih.gov/32536688" }, { "database": "PubMed", "id": "33173197", "url": "https://pubmed.ncbi.nlm.nih.gov/33173197" }, { "database": "PubMed", "id": "35833836", "url": "https://pubmed.ncbi.nlm.nih.gov/35833836" }, { "database": "PubMed", "id": "18498745", "url": "https://pubmed.ncbi.nlm.nih.gov/18498745" } ], "site_lbl": "Ser312", "uniprot_canonical_ac": "P35568-1" } ], "record_id": "pubmed.18160431", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Trauma and hemorrhage-induced acute hepatic insulin resistance: dominant role of tumor necrosis factor-alpha.", "journal": "Endocrinology", "date": "2008", "authors": "Xu J, Kim HT, Ma Y, Zhao L, Zhai L, Kokorina N, Wang P, Messina JL", "reference": { "type": "PubMed", "id": "18187553", "url": "https://pubmed.ncbi.nlm.nih.gov/18187553" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 307, "end_pos": 307, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by RPS6KB1", "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" }, { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "11160134", "url": "https://pubmed.ncbi.nlm.nih.gov/11160134" }, { "database": "PubMed", "id": "11606564", "url": "https://pubmed.ncbi.nlm.nih.gov/11606564" }, { "database": "PubMed", "id": "12409308", "url": "https://pubmed.ncbi.nlm.nih.gov/12409308" }, { "database": "PubMed", "id": "12714600", "url": "https://pubmed.ncbi.nlm.nih.gov/12714600" }, { "database": "PubMed", "id": "12730242", "url": "https://pubmed.ncbi.nlm.nih.gov/12730242" }, { "database": "PubMed", "id": "14556646", "url": "https://pubmed.ncbi.nlm.nih.gov/14556646" }, { "database": "PubMed", "id": "14583092", "url": "https://pubmed.ncbi.nlm.nih.gov/14583092" }, { "database": "PubMed", "id": "14641015", "url": "https://pubmed.ncbi.nlm.nih.gov/14641015" }, { "database": "PubMed", "id": "14697666", "url": "https://pubmed.ncbi.nlm.nih.gov/14697666" }, { "database": "PubMed", "id": "15020250", "url": "https://pubmed.ncbi.nlm.nih.gov/15020250" }, { "database": "PubMed", "id": "15153564", "url": "https://pubmed.ncbi.nlm.nih.gov/15153564" }, { "database": "PubMed", "id": "15582605", "url": "https://pubmed.ncbi.nlm.nih.gov/15582605" }, { "database": "PubMed", "id": "15802620", "url": "https://pubmed.ncbi.nlm.nih.gov/15802620" }, { "database": "PubMed", "id": "16046301", "url": "https://pubmed.ncbi.nlm.nih.gov/16046301" }, { "database": "PubMed", "id": "16055440", "url": "https://pubmed.ncbi.nlm.nih.gov/16055440" }, { "database": "PubMed", "id": "16099428", "url": "https://pubmed.ncbi.nlm.nih.gov/16099428" }, { "database": "PubMed", "id": "16210322", "url": "https://pubmed.ncbi.nlm.nih.gov/16210322" }, { "database": "PubMed", "id": "16269459", "url": "https://pubmed.ncbi.nlm.nih.gov/16269459" }, { "database": "PubMed", "id": "16516141", "url": "https://pubmed.ncbi.nlm.nih.gov/16516141" }, { "database": "PubMed", "id": "16754954", "url": "https://pubmed.ncbi.nlm.nih.gov/16754954" }, { "database": "PubMed", "id": "16839860", "url": "https://pubmed.ncbi.nlm.nih.gov/16839860" }, { "database": "PubMed", "id": "17077083", "url": "https://pubmed.ncbi.nlm.nih.gov/17077083" }, { "database": "PubMed", "id": "17095576", "url": "https://pubmed.ncbi.nlm.nih.gov/17095576" }, { "database": "PubMed", "id": "17276034", "url": "https://pubmed.ncbi.nlm.nih.gov/17276034" }, { "database": "PubMed", "id": "17481767", "url": "https://pubmed.ncbi.nlm.nih.gov/17481767" }, { "database": "PubMed", "id": "17575262", "url": "https://pubmed.ncbi.nlm.nih.gov/17575262" }, { "database": "PubMed", "id": "18187553", "url": "https://pubmed.ncbi.nlm.nih.gov/18187553" }, { "database": "PubMed", "id": "18372392", "url": "https://pubmed.ncbi.nlm.nih.gov/18372392" }, { "database": "PubMed", "id": "18380932", "url": "https://pubmed.ncbi.nlm.nih.gov/18380932" }, { "database": "PubMed", "id": "18496818", "url": "https://pubmed.ncbi.nlm.nih.gov/18496818" }, { "database": "PubMed", "id": "18952604", "url": "https://pubmed.ncbi.nlm.nih.gov/18952604" }, { "database": "PubMed", "id": "19095745", "url": "https://pubmed.ncbi.nlm.nih.gov/19095745" }, { "database": "PubMed", "id": "19524129", "url": "https://pubmed.ncbi.nlm.nih.gov/19524129" }, { "database": "PubMed", "id": "19897715", "url": "https://pubmed.ncbi.nlm.nih.gov/19897715" }, { "database": "PubMed", "id": "20351777", "url": "https://pubmed.ncbi.nlm.nih.gov/20351777" }, { "database": "PubMed", "id": "20382011", "url": "https://pubmed.ncbi.nlm.nih.gov/20382011" }, { "database": "PubMed", "id": "20384568", "url": "https://pubmed.ncbi.nlm.nih.gov/20384568" }, { "database": "PubMed", "id": "20541543", "url": "https://pubmed.ncbi.nlm.nih.gov/20541543" }, { "database": "PubMed", "id": "20587749", "url": "https://pubmed.ncbi.nlm.nih.gov/20587749" }, { "database": "PubMed", "id": "20594161", "url": "https://pubmed.ncbi.nlm.nih.gov/20594161" }, { "database": "PubMed", "id": "20594757", "url": "https://pubmed.ncbi.nlm.nih.gov/20594757" }, { "database": "PubMed", "id": "20702573", "url": "https://pubmed.ncbi.nlm.nih.gov/20702573" }, { "database": "PubMed", "id": "21119656", "url": "https://pubmed.ncbi.nlm.nih.gov/21119656" }, { "database": "PubMed", "id": "21478152", "url": "https://pubmed.ncbi.nlm.nih.gov/21478152" }, { "database": "PubMed", "id": "21505982", "url": "https://pubmed.ncbi.nlm.nih.gov/21505982" }, { "database": "PubMed", "id": "21786209", "url": "https://pubmed.ncbi.nlm.nih.gov/21786209" }, { "database": "PubMed", "id": "21852229", "url": "https://pubmed.ncbi.nlm.nih.gov/21852229" }, { "database": "PubMed", "id": "21900690", "url": "https://pubmed.ncbi.nlm.nih.gov/21900690" }, { "database": "PubMed", "id": "22046423", "url": "https://pubmed.ncbi.nlm.nih.gov/22046423" }, { "database": "PubMed", "id": "22227580", "url": "https://pubmed.ncbi.nlm.nih.gov/22227580" }, { "database": "PubMed", "id": "22266116", "url": "https://pubmed.ncbi.nlm.nih.gov/22266116" }, { "database": "PubMed", "id": "22328823", "url": "https://pubmed.ncbi.nlm.nih.gov/22328823" }, { "database": "PubMed", "id": "22348058", "url": "https://pubmed.ncbi.nlm.nih.gov/22348058" }, { "database": "PubMed", "id": "22491740", "url": "https://pubmed.ncbi.nlm.nih.gov/22491740" }, { "database": "PubMed", "id": "22728372", "url": "https://pubmed.ncbi.nlm.nih.gov/22728372" }, { "database": "PubMed", "id": "22766331", "url": "https://pubmed.ncbi.nlm.nih.gov/22766331" }, { "database": "PubMed", "id": "23095254", "url": "https://pubmed.ncbi.nlm.nih.gov/23095254" }, { "database": "PubMed", "id": "23174405", "url": "https://pubmed.ncbi.nlm.nih.gov/23174405" }, { "database": "PubMed", "id": "23182460", "url": "https://pubmed.ncbi.nlm.nih.gov/23182460" }, { "database": "PubMed", "id": "23481042", "url": "https://pubmed.ncbi.nlm.nih.gov/23481042" }, { "database": "PubMed", "id": "23566306", "url": "https://pubmed.ncbi.nlm.nih.gov/23566306" }, { "database": "PubMed", "id": "23592917", "url": "https://pubmed.ncbi.nlm.nih.gov/23592917" }, { "database": "PubMed", "id": "23891856", "url": "https://pubmed.ncbi.nlm.nih.gov/23891856" }, { "database": "PubMed", "id": "23958494", "url": "https://pubmed.ncbi.nlm.nih.gov/23958494" }, { "database": "PubMed", "id": "24068326", "url": "https://pubmed.ncbi.nlm.nih.gov/24068326" }, { "database": "PubMed", "id": "24846082", "url": "https://pubmed.ncbi.nlm.nih.gov/24846082" }, { "database": "PubMed", "id": "25120613", "url": "https://pubmed.ncbi.nlm.nih.gov/25120613" }, { "database": "PubMed", "id": "25355439", "url": "https://pubmed.ncbi.nlm.nih.gov/25355439" }, { "database": "PubMed", "id": "25645159", "url": "https://pubmed.ncbi.nlm.nih.gov/25645159" }, { "database": "PubMed", "id": "25799226", "url": "https://pubmed.ncbi.nlm.nih.gov/25799226" }, { "database": "PubMed", "id": "26604643", "url": "https://pubmed.ncbi.nlm.nih.gov/26604643" }, { "database": "PubMed", "id": "26698173", "url": "https://pubmed.ncbi.nlm.nih.gov/26698173" }, { "database": "PubMed", "id": "26704265", "url": "https://pubmed.ncbi.nlm.nih.gov/26704265" }, { "database": "PubMed", "id": "26899161", "url": "https://pubmed.ncbi.nlm.nih.gov/26899161" }, { "database": "PubMed", "id": "26983645", "url": "https://pubmed.ncbi.nlm.nih.gov/26983645" }, { "database": "PubMed", "id": "27222060", "url": "https://pubmed.ncbi.nlm.nih.gov/27222060" }, { "database": "PubMed", "id": "27506476", "url": "https://pubmed.ncbi.nlm.nih.gov/27506476" }, { "database": "PubMed", "id": "27544192", "url": "https://pubmed.ncbi.nlm.nih.gov/27544192" }, { "database": "PubMed", "id": "27686967", "url": "https://pubmed.ncbi.nlm.nih.gov/27686967" }, { "database": "PubMed", "id": "27936435", "url": "https://pubmed.ncbi.nlm.nih.gov/27936435" }, { "database": "PubMed", "id": "28161417", "url": "https://pubmed.ncbi.nlm.nih.gov/28161417" }, { "database": "PubMed", "id": "28656239", "url": "https://pubmed.ncbi.nlm.nih.gov/28656239" }, { "database": "PubMed", "id": "28731188", "url": "https://pubmed.ncbi.nlm.nih.gov/28731188" }, { "database": "PubMed", "id": "28790390", "url": "https://pubmed.ncbi.nlm.nih.gov/28790390" }, { "database": "PubMed", "id": "28934129", "url": "https://pubmed.ncbi.nlm.nih.gov/28934129" }, { "database": "PubMed", "id": "29177868", "url": "https://pubmed.ncbi.nlm.nih.gov/29177868" }, { "database": "PubMed", "id": "29311680", "url": "https://pubmed.ncbi.nlm.nih.gov/29311680" }, { "database": "PubMed", "id": "29393871", "url": "https://pubmed.ncbi.nlm.nih.gov/29393871" }, { "database": "PubMed", "id": "29432553", "url": "https://pubmed.ncbi.nlm.nih.gov/29432553" }, { "database": "PubMed", "id": "29698741", "url": "https://pubmed.ncbi.nlm.nih.gov/29698741" }, { "database": "PubMed", "id": "29738527", "url": "https://pubmed.ncbi.nlm.nih.gov/29738527" }, { "database": "PubMed", "id": "30240640", "url": "https://pubmed.ncbi.nlm.nih.gov/30240640" }, { "database": "PubMed", "id": "30374127", "url": "https://pubmed.ncbi.nlm.nih.gov/30374127" }, { "database": "PubMed", "id": "30572687", "url": "https://pubmed.ncbi.nlm.nih.gov/30572687" }, { "database": "PubMed", "id": "31137828", "url": "https://pubmed.ncbi.nlm.nih.gov/31137828" }, { "database": "PubMed", "id": "31311314", "url": "https://pubmed.ncbi.nlm.nih.gov/31311314" }, { "database": "PubMed", "id": "31396538", "url": "https://pubmed.ncbi.nlm.nih.gov/31396538" }, { "database": "PubMed", "id": "32875583", "url": "https://pubmed.ncbi.nlm.nih.gov/32875583" }, { "database": "PubMed", "id": "33723215", "url": "https://pubmed.ncbi.nlm.nih.gov/33723215" }, { "database": "PubMed", "id": "35656886", "url": "https://pubmed.ncbi.nlm.nih.gov/35656886" }, { "database": "PubMed", "id": "18498745", "url": "https://pubmed.ncbi.nlm.nih.gov/18498745" } ], "site_lbl": "Ser307", "uniprot_canonical_ac": "P35568-1" } ], "record_id": "pubmed.18187553", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Phosphorylation of Ser357 of rat insulin receptor substrate-1 mediates adverse effects of protein kinase C-delta on insulin action in skeletal muscle cells.", "journal": "The Journal of biological chemistry", "date": "2008", "authors": "Waraich RS, Weigert C, Kalbacher H, Hennige AM, Lutz SZ, Haring HU, Schleicher ED, Voelter W, Lehmann R", "reference": { "type": "PubMed", "id": "18285345", "url": "https://pubmed.ncbi.nlm.nih.gov/18285345" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P35568", "url": "https://www.uniprot.org/uniprotkb/P35568" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 362, "end_pos": 362, "kinase_uniprot_canonical_ac": "Q05655-1", "kinase_gene_name": "PRKCD", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P35568", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35568" }, { "database": "PubMed", "id": "14583092", "url": "https://pubmed.ncbi.nlm.nih.gov/14583092" }, { "database": "PubMed", "id": "18285345", "url": "https://pubmed.ncbi.nlm.nih.gov/18285345" } ], "site_lbl": "Ser362", "uniprot_canonical_ac": "P35568-1" } ], "record_id": "pubmed.18285345", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] } ]