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Biol. Chem.", "date": "1998", "authors": "Pauly P C, Harris D A", "reference": { "type": "PubMed", "id": "9837873", "url": "https://pubmed.ncbi.nlm.nih.gov/9837873" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P04925-1", "protein_name": "Major prion protein", "gene_name": "Prnp", "tax_name": "Mouse" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P04925", "url": "https://www.uniprot.org/uniprotkb/P04925" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "record_id": "pubmed.9837873", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": 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J.", "date": "1991", "authors": "Carr\u00e9-Eus\u00e8be D, Lederer F, L\u00ea K H, Elsevier S M", "reference": { "type": "PubMed", "id": "1854346", "url": "https://pubmed.ncbi.nlm.nih.gov/1854346" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P07978-1", "protein_name": "Protamine-2", "gene_name": "Prm2", "tax_name": "Mouse" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P07978", "url": "https://www.uniprot.org/uniprotkb/P07978" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "record_id": "pubmed.1854346", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Processing of the precursor of protamine P2 in mouse. 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Biochem.", "date": "1991", "authors": "Elsevier SM, Noiran J, Carre-Eusebe D", "reference": { "type": "PubMed", "id": "2001695", "url": "https://pubmed.ncbi.nlm.nih.gov/2001695" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P07978-1", "protein_name": "Protamine-2", "gene_name": "Prm2", "tax_name": "Mouse" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P07978", "url": "https://www.uniprot.org/uniprotkb/P07978" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "record_id": "pubmed.2001695", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "TDRP deficiency contributes to low sperm motility and is a potential risk factor for male infertility.", "journal": "Am. J. Transl. Res.", "date": "2016", "authors": "Mao Shanhua, Wu Fei, Cao Xinyi, He Min, Liu Naijia, Wu Huihui, Yang Zhihong, Ding Qiang, Wang Xuanchun", "reference": { "type": "PubMed", "id": "27069551", "url": "https://pubmed.ncbi.nlm.nih.gov/27069551" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P07978-1", "protein_name": "Protamine-2", "gene_name": "Prm2", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q86YL5-1", "protein_name": "Testis development-related protein", "gene_name": "TDRP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8C5P7-1", "protein_name": "Testis development-related protein", "gene_name": "Tdrp", "tax_name": "Mouse" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P07978", "url": "https://www.uniprot.org/uniprotkb/P07978" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "record_id": "pubmed.27069551", "abstract": "", 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Mutations in the small GTP-ase late endosomal protein RAB7 cause Charcot-Marie-Tooth type 2B neuropathy.", "journal": "Am. J. Hum. Genet.", "date": "2003", "authors": "Verhoeven K, De Jonghe P, Coen K, Verpoorten N, Auer-Grumbach M, Kwon JM, FitzPatrick D, Schmedding E, De Vriendt E, Jacobs A, Van Gerwen V, Wagner K, Hartung HP, Timmerman V", "reference": { "type": "PubMed", "id": "12545426", "url": "https://pubmed.ncbi.nlm.nih.gov/12545426" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P51150-1", "protein_name": "Ras-related protein Rab-7a", "gene_name": "Rab7a; Rab7", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "P51149-1", "protein_name": "Ras-related protein Rab-7a", "gene_name": "RAB7A", "tax_name": "Human" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P51150", "url": "https://www.uniprot.org/uniprotkb/P51150" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "record_id": "pubmed.12545426", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Rabring7, a novel Rab7 target protein with a RING finger motif.", "journal": "Mol. Biol. Cell", "date": "2003", "authors": "Mizuno K, Kitamura A, Sasaki T", "reference": { "type": "PubMed", "id": "12972561", "url": "https://pubmed.ncbi.nlm.nih.gov/12972561" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P51150-1", "protein_name": "Ras-related protein Rab-7a", "gene_name": "Rab7a; Rab7", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q9D0C1-1", "protein_name": "E3 ubiquitin-protein ligase RNF115", "gene_name": "Rnf115", "tax_name": "Mouse" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P51150", "url": "https://www.uniprot.org/uniprotkb/P51150" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "record_id": "pubmed.12972561", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "TBC-domain GAPs for Rab GTPases accelerate GTP hydrolysis by a dual-finger mechanism.", "journal": "Nature", "date": "2006", "authors": "Pan X, Eathiraj S, Munson M, Lambright DG", "reference": { "type": "PubMed", "id": "16855591", "url": "https://pubmed.ncbi.nlm.nih.gov/16855591" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P51150-1", "protein_name": "Ras-related protein Rab-7a", "gene_name": "Rab7a; 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Biol. Chem.", "date": "2010", "authors": "Kloer DP, Rojas R, Ivan V, Moriyama K, van Vlijmen T, Murthy N, Ghirlando R, van der Sluijs P, Hurley JH, Bonifacino JS", "reference": { "type": "PubMed", "id": "20048159", "url": "https://pubmed.ncbi.nlm.nih.gov/20048159" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P51150-1", "protein_name": "Ras-related protein Rab-7a", "gene_name": "Rab7a; Rab7", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q99KG7-1", "protein_name": "BLOC-3 complex member HPS4", "gene_name": "Hps4", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "P51159-1", "protein_name": "Ras-related protein Rab-27A", "gene_name": "RAB27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQG7-1", "protein_name": "BLOC-3 complex member HPS4", "gene_name": "HPS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92902-1", "protein_name": "BLOC-3 complex member HPS1", "gene_name": "HPS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P56371-1", "protein_name": "Ras-related protein Rab-4A", "gene_name": "Rab4a", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "P51151-1", "protein_name": "Ras-related protein Rab-9A", "gene_name": "RAB9A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9R0M6-1", "protein_name": "Ras-related protein Rab-9A", "gene_name": "Rab9a; 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Inhibits SARS-CoV-2 infection.", "evidence": [ { "database": "UniProtKB", "id": "P51149", "url": "https://www.uniprot.org/uniprotkb/P51149" }, { "database": "PubMed", "id": "12944476", "url": "https://pubmed.ncbi.nlm.nih.gov/12944476" }, { "database": "PubMed", "id": "34159616", "url": "https://pubmed.ncbi.nlm.nih.gov/34159616" }, { "database": "PubMed", "id": "23179371", "url": "https://pubmed.ncbi.nlm.nih.gov/23179371" }, { "database": "PubMed", "id": "30709847", "url": "https://pubmed.ncbi.nlm.nih.gov/30709847" }, { "database": "PubMed", "id": "22431521", "url": "https://pubmed.ncbi.nlm.nih.gov/22431521" } ], "uniprot_canonical_ac": "P51149-1" }, { "start_pos": 67, "end_pos": 67, "sequence_org": "Q", "sequence_mut": "L", "comment": "Does not abolish localization on late endosomes, lysosomes and phagosomes and does not reduce phagosomal fusions. No loss of interaction with CLN5 and VPS13A. Increases interaction with PRPH. Inhibits SARS-CoV-2 infection.", "evidence": [ { "database": "UniProtKB", "id": "P51149", "url": "https://www.uniprot.org/uniprotkb/P51149" }, { "database": "PubMed", "id": "12944476", "url": "https://pubmed.ncbi.nlm.nih.gov/12944476" }, { "database": "PubMed", "id": "34159616", "url": "https://pubmed.ncbi.nlm.nih.gov/34159616" }, { "database": "PubMed", "id": "22431521", "url": "https://pubmed.ncbi.nlm.nih.gov/22431521" }, { "database": "PubMed", "id": "23179371", "url": "https://pubmed.ncbi.nlm.nih.gov/23179371" }, { "database": "PubMed", "id": "30709847", "url": "https://pubmed.ncbi.nlm.nih.gov/30709847" } ], "uniprot_canonical_ac": "P51149-1" } ], "record_id": "pubmed.23179371", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "\u03b2-adrenergic receptor-stimulated lipolysis requires the RAB7-mediated autolysosomal lipid degradation.", "journal": "Autophagy", "date": "2013-08", "authors": "Lizaso Analyn, Tan Kien-Thiam, Lee Ying-Hue", "reference": { "type": "PubMed", "id": "23708524", "url": "https://pubmed.ncbi.nlm.nih.gov/23708524" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P51150-1", "protein_name": "Ras-related protein Rab-7a", "gene_name": "Rab7a; 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Mol. Genet.", "date": "2014", "authors": "Farg Manal A, Sundaramoorthy Vinod, Sultana Jessica M, Yang Shu, Atkinson Rachel A K, Levina Vita, Halloran Mark A, Gleeson Paul A, Blair Ian P, Soo Kai Y, King Anna E, Atkin Julie D", "reference": { "type": "PubMed", "id": "24549040", "url": "https://pubmed.ncbi.nlm.nih.gov/24549040" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P51150-1", "protein_name": "Ras-related protein Rab-7a", "gene_name": "Rab7a; Rab7", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "P09651-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein A1", "gene_name": "HNRNPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62821-1", "protein_name": "Ras-related protein Rab-1A", "gene_name": "Rab1a", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q96LT7-1", "protein_name": "Guanine nucleotide exchange factor C9orf72", "gene_name": "C9orf72", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UHD9-1", "protein_name": 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Biophys. Acta", "date": "1995", "authors": "Vitelli R, Chiariello M, Bruni CB, Bucci C", "reference": { "type": "PubMed", "id": "8547311", "url": "https://pubmed.ncbi.nlm.nih.gov/8547311" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P51150-1", "protein_name": "Ras-related protein Rab-7a", "gene_name": "Rab7a; Rab7", "tax_name": "Mouse" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P51150", "url": "https://www.uniprot.org/uniprotkb/P51150" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "record_id": "pubmed.8547311", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": 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Life sciences", "date": "2024-06", "authors": "Liu Jiaming, Li Liangkui, Xu Dijin, Li Yuqi, Chen Tao, Liu Yeyang, Bao Yuqian, Wang Yan, Yang Longyan, Li Peng, Xu Li", "reference": { "type": "PubMed", "id": "38523235", "url": "https://pubmed.ncbi.nlm.nih.gov/38523235" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35293-1", "protein_name": "Ras-related protein Rab-18", "gene_name": "Rab18", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NP72-1", "protein_name": "Ras-related protein Rab-18", "gene_name": "RAB18", "tax_name": "Human" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P35293", "url": "https://www.uniprot.org/uniprotkb/P35293" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "record_id": "pubmed.38523235", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], 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"journal": "Journal of cell science", "date": "1994", "authors": "Lutcke A, Parton RG, Murphy C, Olkkonen VM, Dupree P, Valencia A, Simons K, Zerial M", "reference": { "type": "PubMed", "id": "7706395", "url": "https://pubmed.ncbi.nlm.nih.gov/7706395" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P35293-1", "protein_name": "Ras-related protein Rab-18", "gene_name": "Rab18", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "P35295-1", "protein_name": "Ras-related protein Rab-20", "gene_name": "Rab20", "tax_name": "Mouse" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P35293", "url": "https://www.uniprot.org/uniprotkb/P35293" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "record_id": "pubmed.7706395", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": 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Natl. Acad. Sci. U.S.A.", "date": "1999", "authors": "Wong P M, Kang A, Chen H, Yuan Q, Fan P, Sultzer B M, Kan Y W, Chung S W", "reference": { "type": "PubMed", "id": "10500213", "url": "https://pubmed.ncbi.nlm.nih.gov/10500213" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P62827-1", "protein_name": "GTP-binding nuclear protein Ran", "gene_name": "Ran", "tax_name": "Mouse" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P62827", "url": "https://www.uniprot.org/uniprotkb/P62827" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "record_id": "pubmed.10500213", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The mammalian Mog1 protein is a guanine nucleotide release factor for Ran.", "journal": "The Journal of biological chemistry", "date": "2000", "authors": "Steggerda SM, Paschal BM", "reference": { "type": "PubMed", "id": "10811801", "url": "https://pubmed.ncbi.nlm.nih.gov/10811801" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P62827-1", "protein_name": "GTP-binding nuclear protein Ran", "gene_name": "Ran", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JIB0-1", "protein_name": "Ran guanine nucleotide release factor", "gene_name": "Rangrf", "tax_name": "Mouse" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P62827", "url": "https://www.uniprot.org/uniprotkb/P62827" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "mutagenesis": [ { "start_pos": 69, "end_pos": 69, "sequence_org": "Q", "sequence_mut": "L", "comment": "Strongly decreases interaction with RANGRF. 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"count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "RanBP10 is a cytoplasmic guanine nucleotide exchange factor that modulates noncentrosomal microtubules.", "journal": "The Journal of biological chemistry", "date": "2008", "authors": "Schulze H, Dose M, Korpal M, Meyer I, Italiano JE Jr, Shivdasani RA", "reference": { "type": "PubMed", "id": "18347012", "url": "https://pubmed.ncbi.nlm.nih.gov/18347012" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P62827-1", "protein_name": "GTP-binding nuclear protein Ran", "gene_name": "Ran", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q6VN19-1", "protein_name": "Ran-binding protein 10", "gene_name": "Ranbp10", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q6VN20-1", "protein_name": "Ran-binding protein 10", "gene_name": "RANBP10", "tax_name": "Human" }, { "uniprot_canonical_ac": "P99024-1", "protein_name": "Tubulin 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No effect on interaction with NEMP1 and KPNB1.", "evidence": [ { "database": "UniProtKB", "id": "P62827", "url": "https://www.uniprot.org/uniprotkb/P62827" }, { "database": "PubMed", "id": "18347012", "url": "https://pubmed.ncbi.nlm.nih.gov/18347012" }, { "database": "PubMed", "id": "10811801", "url": "https://pubmed.ncbi.nlm.nih.gov/10811801" }, { "database": "PubMed", "id": "25946333", "url": "https://pubmed.ncbi.nlm.nih.gov/25946333" } ], "uniprot_canonical_ac": "P62827-1" }, { "start_pos": 301, "end_pos": 301, "sequence_org": "L", "sequence_mut": "I", "comment": "Complete loss RAN-GEF activity. Partial loss of RAN-binding.", "evidence": [ { "database": "UniProtKB", "id": "Q6VN19", "url": "https://www.uniprot.org/uniprotkb/Q6VN19" }, { "database": "PubMed", "id": "18347012", "url": "https://pubmed.ncbi.nlm.nih.gov/18347012" } ], "uniprot_canonical_ac": "Q6VN19-1" } ], "record_id": "pubmed.18347012", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 6 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The Inner Nuclear Membrane Protein Nemp1 Is a New Type of RanGTP-Binding Protein in Eukaryotes.", "journal": "PloS one", "date": "2015", "authors": "Shibano T, Mamada H, Hakuno F, Takahashi S, Taira M", "reference": { "type": "PubMed", "id": "25946333", "url": "https://pubmed.ncbi.nlm.nih.gov/25946333" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P62827-1", "protein_name": "GTP-binding nuclear protein Ran", "gene_name": "Ran", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "P70168-1", "protein_name": "Importin subunit beta-1", "gene_name": "Kpnb1", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q6ZQE4-1", "protein_name": "Nuclear envelope integral membrane protein 1", "gene_name": "Nemp1", "tax_name": "Mouse" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P62827", "url": "https://www.uniprot.org/uniprotkb/P62827" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "mutagenesis": [ { "start_pos": 24, "end_pos": 24, "sequence_org": "T", "sequence_mut": "N", "comment": "No effect on RANBP10-binding. 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No effect on interaction with NEMP1 and KPNB1.", "evidence": [ { "database": "UniProtKB", "id": "P62827", "url": "https://www.uniprot.org/uniprotkb/P62827" }, { "database": "PubMed", "id": "18347012", "url": "https://pubmed.ncbi.nlm.nih.gov/18347012" }, { "database": "PubMed", "id": "10811801", "url": "https://pubmed.ncbi.nlm.nih.gov/10811801" }, { "database": "PubMed", "id": "25946333", "url": "https://pubmed.ncbi.nlm.nih.gov/25946333" } ], "uniprot_canonical_ac": "P62827-1" }, { "start_pos": 366, "end_pos": 366, "sequence_org": "S", "sequence_mut": "A", "comment": "Partial loss of phosphorylation and loss of interaction with RAN-GTP; when associated with A/E-376; A/E-380; A/E-419 and A/E-420.", "evidence": [ { "database": "UniProtKB", "id": "Q6ZQE4", "url": "https://www.uniprot.org/uniprotkb/Q6ZQE4" }, { "database": "PubMed", "id": "25946333", "url": "https://pubmed.ncbi.nlm.nih.gov/25946333" } ], "uniprot_canonical_ac": "Q6ZQE4-1" }, { "start_pos": 366, "end_pos": 366, "sequence_org": "S", "sequence_mut": "E", "comment": "Partial loss of phosphorylation and loss of interaction with RAN-GTP; when associated with A/E-376; A/E-380; A/E-419 and A/E-420.", "evidence": [ { "database": "UniProtKB", "id": "Q6ZQE4", "url": "https://www.uniprot.org/uniprotkb/Q6ZQE4" }, { "database": "PubMed", "id": "25946333", "url": "https://pubmed.ncbi.nlm.nih.gov/25946333" } ], "uniprot_canonical_ac": "Q6ZQE4-1" }, { "start_pos": 376, "end_pos": 376, "sequence_org": "S", "sequence_mut": "A", "comment": "Partial loss of phosphorylation and loss of interaction with RAN-GTP; when associated with A/E-366; A/E-380; A/E-419 and A/E-420.", "evidence": [ { "database": "UniProtKB", "id": "Q6ZQE4", "url": "https://www.uniprot.org/uniprotkb/Q6ZQE4" }, { "database": "PubMed", "id": "25946333", "url": "https://pubmed.ncbi.nlm.nih.gov/25946333" } ], "uniprot_canonical_ac": "Q6ZQE4-1" }, { "start_pos": 376, "end_pos": 376, "sequence_org": "S", "sequence_mut": "E", "comment": "Partial loss of phosphorylation and loss of interaction with RAN-GTP; when associated with A/E-366; A/E-380; A/E-419 and A/E-420.", "evidence": [ { "database": "UniProtKB", "id": "Q6ZQE4", "url": "https://www.uniprot.org/uniprotkb/Q6ZQE4" }, { "database": "PubMed", "id": "25946333", "url": "https://pubmed.ncbi.nlm.nih.gov/25946333" } ], "uniprot_canonical_ac": "Q6ZQE4-1" }, { "start_pos": 380, "end_pos": 380, "sequence_org": "S", "sequence_mut": "A", "comment": "Partial loss of phosphorylation and loss of interaction with RAN-GTP; when associated with A/E-366; A/E-376; A/E-419 and A/E-420.", "evidence": [ { "database": "UniProtKB", "id": "Q6ZQE4", "url": "https://www.uniprot.org/uniprotkb/Q6ZQE4" }, { "database": "PubMed", "id": "25946333", "url": "https://pubmed.ncbi.nlm.nih.gov/25946333" } ], "uniprot_canonical_ac": "Q6ZQE4-1" }, { "start_pos": 380, "end_pos": 380, "sequence_org": "S", "sequence_mut": "E", "comment": "Partial loss of phosphorylation and loss of interaction with RAN-GTP; when associated with A/E-366; A/E-376; A/E-419 and A/E-420.", "evidence": [ { "database": "UniProtKB", "id": "Q6ZQE4", "url": "https://www.uniprot.org/uniprotkb/Q6ZQE4" }, { "database": "PubMed", "id": "25946333", "url": "https://pubmed.ncbi.nlm.nih.gov/25946333" } ], "uniprot_canonical_ac": "Q6ZQE4-1" }, { "start_pos": 419, "end_pos": 419, "sequence_org": "S", "sequence_mut": "A", "comment": "Partial loss of phosphorylation and loss of interaction with RAN; when associated with A/E-366; A/E-376; A/E-380 and A/E-420.", "evidence": [ { "database": "UniProtKB", "id": "Q6ZQE4", "url": "https://www.uniprot.org/uniprotkb/Q6ZQE4" }, { "database": "PubMed", "id": "25946333", "url": "https://pubmed.ncbi.nlm.nih.gov/25946333" } ], "uniprot_canonical_ac": "Q6ZQE4-1" }, { "start_pos": 419, "end_pos": 419, "sequence_org": "S", "sequence_mut": "E", "comment": "Partial loss of phosphorylation and loss of interaction with RAN; when associated with A/E-366; A/E-376; A/E-380 and A/E-420.", "evidence": [ { "database": "UniProtKB", "id": "Q6ZQE4", "url": "https://www.uniprot.org/uniprotkb/Q6ZQE4" }, { "database": "PubMed", "id": "25946333", "url": "https://pubmed.ncbi.nlm.nih.gov/25946333" } ], "uniprot_canonical_ac": "Q6ZQE4-1" }, { "start_pos": 420, "end_pos": 420, "sequence_org": "S", "sequence_mut": "A", "comment": "Partial loss of phosphorylation and loss of interaction with RAN-GTP; when associated with A/E-366; A/E-376; A/E-380 and A/E-419.", "evidence": [ { "database": "UniProtKB", "id": "Q6ZQE4", "url": "https://www.uniprot.org/uniprotkb/Q6ZQE4" }, { "database": "PubMed", "id": "25946333", "url": "https://pubmed.ncbi.nlm.nih.gov/25946333" } ], "uniprot_canonical_ac": "Q6ZQE4-1" }, { "start_pos": 420, "end_pos": 420, "sequence_org": "S", "sequence_mut": "E", "comment": "Partial loss of phosphorylation and loss of interaction with RAN-GTP; when associated with A/E-366; A/E-376; A/E-380 and A/E-419.", "evidence": [ { "database": "UniProtKB", "id": "Q6ZQE4", "url": "https://www.uniprot.org/uniprotkb/Q6ZQE4" }, { "database": "PubMed", "id": "25946333", "url": "https://pubmed.ncbi.nlm.nih.gov/25946333" } ], "uniprot_canonical_ac": "Q6ZQE4-1" } ], "record_id": "pubmed.25946333", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "MYCBP2 is a guanosine exchange factor for Ran protein and determines its localization in neurons of dorsal root ganglia.", "journal": "J. Biol. Chem.", "date": "2015", "authors": "Dorr A, Pierre S, Zhang DD, Henke M, Holland S, Scholich K", "reference": { "type": "PubMed", "id": "26304119", "url": "https://pubmed.ncbi.nlm.nih.gov/26304119" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P62827-1", "protein_name": "GTP-binding nuclear protein Ran", "gene_name": "Ran", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "P62826-1", "protein_name": "GTP-binding nuclear protein Ran", "gene_name": "RAN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46061-1", "protein_name": "Ran GTPase-activating protein 1", "gene_name": "Rangap1", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "O75592-1", "protein_name": "E3 ubiquitin-protein ligase MYCBP2", "gene_name": "MYCBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46060-1", "protein_name": "Ran GTPase-activating protein 1", "gene_name": "RANGAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7TPH6-1", "protein_name": "E3 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Genome", "date": "1994", "authors": "Coutavas E E, Hsieh C M, Ren M, Drivas G T, Rush M G, D'Eustachio P D", "reference": { "type": "PubMed", "id": "7849398", "url": "https://pubmed.ncbi.nlm.nih.gov/7849398" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P62827-1", "protein_name": "GTP-binding nuclear protein Ran", "gene_name": "Ran", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q61820-1", "protein_name": "GTP-binding nuclear protein Ran, testis-specific isoform", "gene_name": "Rasl2-9", "tax_name": "Mouse" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P62827", "url": "https://www.uniprot.org/uniprotkb/P62827" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "record_id": "pubmed.7849398", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Separate domains of the Ran GTPase interact with different factors to regulate nuclear protein import and RNA processing.", "journal": "Mol. Cell. Biol.", "date": "1995", "authors": "Ren M, Villamarin A, Shih A, Coutavas E, Moore MS, LoCurcio M, Clarke V, Oppenheim JD, D'Eustachio P, Rush MG", "reference": { "type": "PubMed", "id": "7891706", "url": "https://pubmed.ncbi.nlm.nih.gov/7891706" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P62827-1", "protein_name": "GTP-binding nuclear protein Ran", "gene_name": "Ran", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "P62826-1", "protein_name": "GTP-binding nuclear protein Ran", "gene_name": "RAN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46061-1", "protein_name": "Ran GTPase-activating protein 1", "gene_name": "Rangap1", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "P34022-1", "protein_name": "Ran-specific GTPase-activating protein", "gene_name": "Ranbp1", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "P43487-1", "protein_name": "Ran-specific GTPase-activating protein", "gene_name": "RANBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46060-1", "protein_name": "Ran GTPase-activating protein 1", "gene_name": "RANGAP1", "tax_name": "Human" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P62827", "url": "https://www.uniprot.org/uniprotkb/P62827" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "mutagenesis": [ { "start_pos": 211, "end_pos": 216, "sequence_org": "DEDDDL", "sequence_mut": "", "comment": "No effect on GTPase activity. 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"RASEF/Rab45 regulates the formation and sorting of zymogen granules and secretion of digestive enzymes by pancreatic acinar cells.", "journal": "Biochimica et biophysica acta. 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Biophys. Res. Commun.", "date": "2006", "authors": "Tsukamoto Satoshi, Ihara Ryo, Aizawa Akira, Kishida Shosei, Kikuchi Akira, Imai Hiroshi, Minami Naojiro", "reference": { "type": "PubMed", "id": "16580637", "url": "https://pubmed.ncbi.nlm.nih.gov/16580637" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q61411-1", "protein_name": "GTPase HRas", "gene_name": "Hras", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q03385-1", "protein_name": "Ral guanine nucleotide dissociation stimulator", "gene_name": "Ralgds", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q5G7-1", "protein_name": "Oogenesin-1", "gene_name": "Gm2042; Oog1", "tax_name": "Mouse" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q61411", "url": "https://www.uniprot.org/uniprotkb/Q61411" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "record_id": "pubmed.16580637", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Ras is an indispensable coregulator of the class IB phosphoinositide 3-kinase p87/p110gamma.", "journal": "Proc. 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U.S.A.", "date": "2009", "authors": "Kurig Barbara, Shymanets Aliaksei, Bohnacker Thomas, Prajwal , Brock Carsten, Ahmadian Mohammad Reza, Schaefer Michael, Gohla Antje, Harteneck Christian, Wymann Matthias P, Jeanclos Elisabeth, N\u00fcrnberg Bernd", "reference": { "type": "PubMed", "id": "19906996", "url": "https://pubmed.ncbi.nlm.nih.gov/19906996" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q61411-1", "protein_name": "GTPase HRas", "gene_name": "Hras", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q3U6Q4-1", "protein_name": "Phosphoinositide 3-kinase regulatory subunit 6", "gene_name": "Pik3r6", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JHG7-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform", "gene_name": "Pik3cg", "tax_name": "Mouse" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q61411", "url": 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differentiation via the SASP-lipid 15d-PGJ2 mediated modification and control of HRas.", "journal": "eLife", "date": "2024-08-28", "authors": "Pundlik Swarang Sachin, Barik Alok, Venkateshvaran Ashwin, Sahoo Snehasudha Subhadarshini, Jaysingh Mahapatra Anshuman, Math Raviswamy G H, Lal Heera, Hashmi Maroof Athar, Ramanathan Arvind", "reference": { "type": "PubMed", "id": "39196610", "url": "https://pubmed.ncbi.nlm.nih.gov/39196610" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q61411-1", "protein_name": "GTPase HRas", "gene_name": "Hras", "tax_name": "Mouse" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q61411", "url": "https://www.uniprot.org/uniprotkb/Q61411" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "record_id": "pubmed.39196610", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], 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"species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q60855", "url": "https://www.uniprot.org/uniprotkb/Q60855" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "record_id": "pubmed.18239685", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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Biol. 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Knockin mice are viable.", "evidence": [ { "database": "UniProtKB", "id": "Q60855", "url": "https://www.uniprot.org/uniprotkb/Q60855" }, { "database": "PubMed", "id": "24557836", "url": "https://pubmed.ncbi.nlm.nih.gov/24557836" } ], "uniprot_canonical_ac": "Q60855-1" }, { "start_pos": 161, "end_pos": 161, "sequence_org": "D", "sequence_mut": "N", "comment": "Abolished protein kinase activity and ability to activate necroptosis. Knockin mice die during embryogenesis due to constitutive Ripk1- and Casp8-dependent apoptosis. 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Death-domain dimerization-mediated activation of RIPK1 controls necroptosis and RIPK1-dependent apoptosis.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2018", "authors": "Meng H, Liu Z, Li X, Wang H, Jin T, Wu G, Shan B, Christofferson DE, Qi C, Yu Q, Li Y, Yuan J", "reference": { "type": "PubMed", "id": "29440439", "url": "https://pubmed.ncbi.nlm.nih.gov/29440439" }, 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"Blocks homodimerization, activation of its kinase activity, formation of complex IIa, necroptosis and apoptosis.", "evidence": [ { "database": "UniProtKB", "id": "Q60855", "url": "https://www.uniprot.org/uniprotkb/Q60855" }, { "database": "PubMed", "id": "29440439", "url": "https://pubmed.ncbi.nlm.nih.gov/29440439" } ], "uniprot_canonical_ac": "Q60855-1" }, { "start_pos": 599, "end_pos": 599, "sequence_org": "K", "sequence_mut": "R", "comment": "Blocks homodimerization, necroptosis and apoptosis.", "evidence": [ { "database": "UniProtKB", "id": "Q13546", "url": "https://www.uniprot.org/uniprotkb/Q13546" }, { "database": "PubMed", "id": "29440439", "url": "https://pubmed.ncbi.nlm.nih.gov/29440439" } ], "uniprot_canonical_ac": "Q13546-1" } ], "phosphorylation": [ { "start_pos": 166, "end_pos": 166, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by autocatalysis", "evidence": [ { "database": "UniProtKB", "id": "Q60855", "url": 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"field": "total", "count": 4 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "PELI1 selectively targets kinase-active RIP3 for ubiquitylation-dependent proteasomal degradation.", "journal": "Mol. Cell", "date": "2018", "authors": "Choi SW, Park HH, Kim S, Chung JM, Noh HJ, Kim SK, Song HK, Lee CW, Morgan MJ, Kang HC, Kim YS", "reference": { "type": "PubMed", "id": "29883609", "url": "https://pubmed.ncbi.nlm.nih.gov/29883609" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q60855-1", "protein_name": "Receptor-interacting serine/threonine-protein kinase 1", "gene_name": "Ripk1", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q16543-1", "protein_name": "Hsp90 co-chaperone Cdc37", "gene_name": "CDC37", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98170-1", "protein_name": "E3 ubiquitin-protein ligase XIAP", "gene_name": "XIAP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13546-1", "protein_name": "Receptor-interacting serine/threonine-protein kinase 1", "gene_name": "RIPK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68036-1", "protein_name": "Ubiquitin-conjugating enzyme E2 L3", "gene_name": "UBE2L3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96FA3-1", "protein_name": "E3 ubiquitin-protein ligase pellino homolog 1", "gene_name": "PELI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96J02-1", "protein_name": "E3 ubiquitin-protein ligase Itchy homolog", "gene_name": "ITCH", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUM4-1", "protein_name": "Programmed cell death 6-interacting protein", "gene_name": "PDCD6IP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13158-1", "protein_name": "FAS-associated death domain protein", "gene_name": "FADD", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07900-1", "protein_name": "Heat shock protein HSP 90-alpha", "gene_name": "HSP90AA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60260-1", "protein_name": "E3 ubiquitin-protein ligase parkin", "gene_name": "PRKN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14790-1", "protein_name": "Caspase-8", "gene_name": "CASP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15628-1", "protein_name": "Tumor necrosis factor receptor type 1-associated DEATH domain protein", "gene_name": "TRADD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13490-1", "protein_name": "Baculoviral IAP repeat-containing protein 2", "gene_name": "BIRC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y572-1", "protein_name": "Receptor-interacting serine/threonine-protein kinase 3", "gene_name": "RIPK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13489-1", "protein_name": "Baculoviral IAP repeat-containing protein 3", "gene_name": "BIRC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8C669-1", "protein_name": "E3 ubiquitin-protein ligase pellino homolog 1", "gene_name": "Peli1", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "O15294-1", "protein_name": "UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit", "gene_name": "OGT", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51617-1", "protein_name": "Interleukin-1 receptor-associated kinase 1", "gene_name": "IRAK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60566-1", "protein_name": "Mitotic checkpoint serine/threonine-protein kinase BUB1 beta", "gene_name": "BUB1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14254-1", "protein_name": "Flotillin-2", "gene_name": "FLOT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NB16-1", "protein_name": "Mixed lineage kinase domain-like protein", "gene_name": "MLKL", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75955-1", "protein_name": "Flotillin-1", "gene_name": "FLOT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12933-1", "protein_name": "TNF receptor-associated factor 2", "gene_name": "TRAF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00560-1", "protein_name": "Syntenin-1", "gene_name": "SDCBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNE7-1", "protein_name": "E3 ubiquitin-protein ligase CHIP", "gene_name": "STUB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9QZL0-1", "protein_name": "Receptor-interacting serine/threonine-protein kinase 3", "gene_name": "Ripk3", "tax_name": "Mouse" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q60855", "url": "https://www.uniprot.org/uniprotkb/Q60855" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "mutagenesis": [ { "start_pos": 104, "end_pos": 104, "sequence_org": "R", "sequence_mut": "A", "comment": "Loss of ability to ubiquitinate RIPK3. Loss of interaction with RIPK1, IRAK1 and RIPK3.", "evidence": [ { "database": "UniProtKB", "id": "Q96FA3", "url": "https://www.uniprot.org/uniprotkb/Q96FA3" }, { "database": "PubMed", "id": "29883609", "url": "https://pubmed.ncbi.nlm.nih.gov/29883609" } ], "uniprot_canonical_ac": "Q96FA3-1" }, { "start_pos": 313, "end_pos": 313, "sequence_org": "H", "sequence_mut": "A", "comment": "Loss of ability to ubiquitinate RIPK3 and NBN. No loss of interaction with RIPK3.", "evidence": [ { "database": "UniProtKB", "id": "Q96FA3", "url": "https://www.uniprot.org/uniprotkb/Q96FA3" }, { "database": "PubMed", "id": "29883609", "url": "https://pubmed.ncbi.nlm.nih.gov/29883609" }, { "database": "PubMed", "id": "30952868", "url": "https://pubmed.ncbi.nlm.nih.gov/30952868" } ], "uniprot_canonical_ac": "Q96FA3-1" }, { "start_pos": 336, "end_pos": 336, "sequence_org": "C", "sequence_mut": "A", "comment": "Loss of ability to ubiquitinate RIPK3 and NBN. No loss of interaction with RIPK3.", "evidence": [ { "database": "UniProtKB", "id": "Q96FA3", "url": "https://www.uniprot.org/uniprotkb/Q96FA3" }, { "database": "PubMed", "id": "29883609", "url": "https://pubmed.ncbi.nlm.nih.gov/29883609" }, { "database": "PubMed", "id": "30952868", "url": "https://pubmed.ncbi.nlm.nih.gov/30952868" } ], "uniprot_canonical_ac": "Q96FA3-1" }, { "start_pos": 182, "end_pos": 182, "sequence_org": "T", "sequence_mut": "A", "comment": "Abolishes kinase activity. Loss of interaction with PELI1 and PELI1-mediated ubiquitination. No loss of interaction with STUB1 and STUB1-mediated ubiquitination. No loss of interaction with RIPK1. Loss of ability to mediate TNF-induced necroptosis. Loss of autophosphorylation at Ser-227.", "evidence": [ { "database": "UniProtKB", "id": "Q9Y572", "url": "https://www.uniprot.org/uniprotkb/Q9Y572" }, { "database": "PubMed", "id": "29883609", "url": "https://pubmed.ncbi.nlm.nih.gov/29883609" } ], "uniprot_canonical_ac": "Q9Y572-1" }, { "start_pos": 182, "end_pos": 182, "sequence_org": "T", "sequence_mut": "S", "comment": "No loss of interaction with PELI1 and PELI1-mediated ubiquitination. No loss of interaction with RIPK1 and MLKL.", "evidence": [ { "database": "UniProtKB", "id": "Q9Y572", "url": "https://www.uniprot.org/uniprotkb/Q9Y572" }, { "database": "PubMed", "id": "29883609", "url": "https://pubmed.ncbi.nlm.nih.gov/29883609" } ], "uniprot_canonical_ac": "Q9Y572-1" }, { "start_pos": 185, "end_pos": 185, "sequence_org": "Y", "sequence_mut": "A", "comment": "Loss of interaction with PELI1 and PELI1-mediated ubiquitination.", "evidence": [ { "database": "UniProtKB", "id": "Q9Y572", "url": "https://www.uniprot.org/uniprotkb/Q9Y572" }, { "database": "PubMed", "id": "29883609", "url": "https://pubmed.ncbi.nlm.nih.gov/29883609" } ], "uniprot_canonical_ac": "Q9Y572-1" }, { "start_pos": 185, "end_pos": 185, "sequence_org": "Y", "sequence_mut": "F", "comment": "Loss of interaction with PELI1 and PELI1-mediated ubiquitination.", "evidence": [ { "database": "UniProtKB", "id": "Q9Y572", "url": "https://www.uniprot.org/uniprotkb/Q9Y572" }, { "database": "PubMed", "id": "29883609", "url": "https://pubmed.ncbi.nlm.nih.gov/29883609" } ], "uniprot_canonical_ac": "Q9Y572-1" }, { "start_pos": 227, "end_pos": 227, "sequence_org": "S", "sequence_mut": "A", "comment": "Abolishes ability to mediate necroptosis. Partial loss of kinase activity. No loss of PELI1-mediated degradation.", "evidence": [ { "database": "UniProtKB", "id": "Q9Y572", "url": "https://www.uniprot.org/uniprotkb/Q9Y572" }, { "database": "PubMed", "id": "22265413", "url": "https://pubmed.ncbi.nlm.nih.gov/22265413" }, { "database": "PubMed", "id": "29883609", "url": "https://pubmed.ncbi.nlm.nih.gov/29883609" } ], "uniprot_canonical_ac": "Q9Y572-1" }, { "start_pos": 227, "end_pos": 227, "sequence_org": "S", "sequence_mut": "D", "comment": "No loss of PELI1-mediated degradation.", "evidence": [ { "database": "UniProtKB", "id": "Q9Y572", "url": "https://www.uniprot.org/uniprotkb/Q9Y572" }, { "database": "PubMed", "id": "29883609", "url": "https://pubmed.ncbi.nlm.nih.gov/29883609" } ], "uniprot_canonical_ac": "Q9Y572-1" }, { "start_pos": 363, "end_pos": 363, "sequence_org": "K", "sequence_mut": "R", "comment": "Loss of PELI1-mediated ubiquitination. 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"count": 0 } ], "sort_fields": [] } ] }, { "title": "RIPK1 prevents TRADD-driven, but TNFR1 independent, apoptosis during development.", "journal": "Cell death and differentiation", "date": "2019", "authors": "Anderton H, Bandala-Sanchez E, Simpson DS, Rickard JA, Ng AP, Di Rago L, Hall C, Vince JE, Silke J, Liccardi G, Feltham R", "reference": { "type": "PubMed", "id": "30185824", "url": "https://pubmed.ncbi.nlm.nih.gov/30185824" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q60855-1", "protein_name": "Receptor-interacting serine/threonine-protein kinase 1", "gene_name": "Ripk1", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q61160-1", "protein_name": "FAS-associated death domain protein", "gene_name": "Fadd", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q3U0V2-1", "protein_name": "Tumor necrosis factor receptor type 1-associated DEATH domain protein", "gene_name": "Tradd", "tax_name": "Mouse" } ], "species": [ { "name": "Mus musculus", 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], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Ripoptocide - A Spark for Inflammation.", "journal": "Front. Cell Dev. Biol.", "date": "2019", "authors": "Ang Rosalind L, Chan Mark, Ting Adrian T", "reference": { "type": "PubMed", "id": "31457011", "url": "https://pubmed.ncbi.nlm.nih.gov/31457011" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q60855-1", "protein_name": "Receptor-interacting serine/threonine-protein kinase 1", "gene_name": "Ripk1", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q13546-1", "protein_name": "Receptor-interacting serine/threonine-protein kinase 1", "gene_name": "RIPK1", "tax_name": "Human" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q60855", "url": "https://www.uniprot.org/uniprotkb/Q60855" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "record_id": "pubmed.31457011", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Cleavage of RIPK1 by caspase-8 is crucial for limiting apoptosis and necroptosis.", "journal": "Nature", "date": "2019", "authors": "Newton K, Wickliffe KE, Dugger DL, Maltzman A, Roose-Girma M, Dohse M, Komuves L, Webster JD, Dixit VM", "reference": { "type": "PubMed", "id": "31511692", "url": "https://pubmed.ncbi.nlm.nih.gov/31511692" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q60855-1", "protein_name": "Receptor-interacting serine/threonine-protein kinase 1", "gene_name": "Ripk1", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q14164-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit epsilon", "gene_name": "IKBKE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UHD2-1", "protein_name": "Serine/threonine-protein kinase TBK1", "gene_name": "TBK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15111-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit alpha", "gene_name": "CHUK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98170-1", "protein_name": "E3 ubiquitin-protein ligase XIAP", "gene_name": "XIAP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13546-1", "protein_name": "Receptor-interacting serine/threonine-protein kinase 1", "gene_name": "RIPK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75385-1", "protein_name": 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Promotes both FADD-dependent apoptosis and RIPK3-dependent necroptosis, thus leading to embryonic lethality at midgestation stages in knockin mice. 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Genome", "date": "2001", "authors": "Fauser S, Aslanukov A, Roepman R, Ferreira P A", "reference": { "type": "PubMed", "id": "11353387", "url": "https://pubmed.ncbi.nlm.nih.gov/11353387" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9ERU9-1", "protein_name": "E3 SUMO-protein ligase RanBP2", "gene_name": "Ranbp2", "tax_name": "Mouse" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ERU9", "url": "https://www.uniprot.org/uniprotkb/Q9ERU9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "record_id": "pubmed.11353387", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Parkin ubiquitinates and promotes the degradation of RanBP2.", "journal": "J. Biol. Chem.", "date": "2006", "authors": "Um JW, Min DS, Rhim H, Kim J, Paik SR, Chung KC", "reference": { "type": "PubMed", "id": "16332688", "url": "https://pubmed.ncbi.nlm.nih.gov/16332688" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9ERU9-1", "protein_name": "E3 SUMO-protein ligase RanBP2", "gene_name": "Ranbp2", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "O60260-1", "protein_name": "E3 ubiquitin-protein ligase parkin", "gene_name": "PRKN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49792-1", "protein_name": "E3 SUMO-protein ligase RanBP2", "gene_name": "RANBP2", "tax_name": "Human" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ERU9", "url": "https://www.uniprot.org/uniprotkb/Q9ERU9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "record_id": "pubmed.16332688", "abstract": "", "glycosylation": [], "mutagenesis": [], 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Cell Biol.", "date": "1995", "authors": "Wilken N, Sen\u00e9cal J L, Scheer U, Dabauvalle M C", "reference": { "type": "PubMed", "id": "8603673", "url": "https://pubmed.ncbi.nlm.nih.gov/8603673" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9ERU9-1", "protein_name": "E3 SUMO-protein ligase RanBP2", "gene_name": "Ranbp2", "tax_name": "Mouse" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ERU9", "url": "https://www.uniprot.org/uniprotkb/Q9ERU9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "record_id": "pubmed.8603673", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": 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