[
    {
        "title": "Chk1 regulates the S phase checkpoint by coupling the physiological turnover and ionizing radiation-induced accelerated proteolysis of Cdc25A.",
        "journal": "Cancer cell",
        "date": "2003",
        "authors": "Sorensen CS, Syljuasen RG, Falck J, Schroeder T, Ronnstrand L, Khanna KK, Zhou BB, Bartek J, Lukas J",
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    {
        "title": "Chk1 mediates S and G2 arrests through Cdc25A degradation in response to DNA-damaging agents.",
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                "uniprot_canonical_ac": "Q6PCT2-1",
                "protein_name": "F-box/LRR-repeat protein 19",
                "gene_name": "FBXL19",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N461-1",
                "protein_name": "F-box/LRR-repeat protein 16",
                "gene_name": "FBXL16",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25789-1",
                "protein_name": "Proteasome subunit alpha type-4",
                "gene_name": "PSMA4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H2C0-1",
                "protein_name": "Gigaxonin",
                "gene_name": "GAN",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15345-2",
                "protein_name": "Leucine-rich repeat-containing protein 41",
                "gene_name": "LRRC41",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96MP8-1",
                "protein_name": "BTB/POZ domain-containing protein KCTD7",
                "gene_name": "KCTD7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9JR72-1",
                "protein_name": "Kelch repeat and BTB domain-containing protein 13",
                "gene_name": "KBTBD13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H0H3-1",
                "protein_name": "Kelch-like protein 25",
                "gene_name": "KLHL25",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UJP4-1",
                "protein_name": "Kelch-like protein 21",
                "gene_name": "KLHL21",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96L50-1",
                "protein_name": "Leucine-rich repeat protein 1",
                "gene_name": "LRR1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62191-1",
                "protein_name": "26S proteasome regulatory subunit 4",
                "gene_name": "PSMC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UBW8-1",
                "protein_name": "COP9 signalosome complex subunit 7a",
                "gene_name": "COPS7A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99627-1",
                "protein_name": "COP9 signalosome complex subunit 8",
                "gene_name": "COPS8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O75147-3",
                "protein_name": "Obscurin-like protein 1",
                "gene_name": "OBSL1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49720-1",
                "protein_name": "Proteasome subunit beta type-3",
                "gene_name": "PSMB3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99460-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 1",
                "gene_name": "PSMD1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UNM6-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 13",
                "gene_name": "PSMD13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P51665-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 7",
                "gene_name": "PSMD7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NSE2-1",
                "protein_name": "Cytokine-inducible SH2-containing protein",
                "gene_name": "CISH",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13309-1",
                "protein_name": "S-phase kinase-associated protein 2",
                "gene_name": "SKP2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Z2X8-1",
                "protein_name": "Kelch-like ECH-associated protein 1",
                "gene_name": "Keap1",
                "tax_name": "Mouse"
            },
            {
                "uniprot_canonical_ac": "Q9BR09-1",
                "protein_name": "Neuralized-like protein 2",
                "gene_name": "NEURL2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28074-1",
                "protein_name": "Proteasome subunit beta type-5",
                "gene_name": "PSMB5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P35998-1",
                "protein_name": "26S proteasome regulatory subunit 7",
                "gene_name": "PSMC2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P43686-1",
                "protein_name": "26S proteasome regulatory subunit 6B",
                "gene_name": "PSMC4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99436-1",
                "protein_name": "Proteasome subunit beta type-7",
                "gene_name": "PSMB7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15392-1",
                "protein_name": "Baculoviral IAP repeat-containing protein 5",
                "gene_name": "BIRC5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5XUX0-1",
                "protein_name": "F-box only protein 31",
                "gene_name": "FBXO31",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15370-1",
                "protein_name": "Elongin-B",
                "gene_name": "ELOB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61077-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 D3",
                "gene_name": "UBE2D3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P51668-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 D1",
                "gene_name": "UBE2D1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O14508-1",
                "protein_name": "Suppressor of cytokine signaling 2",
                "gene_name": "SOCS2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q16531-1",
                "protein_name": "DNA damage-binding protein 1",
                "gene_name": "DDB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXI3-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 10",
                "gene_name": "ASB10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13200-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 2",
                "gene_name": "PSMD2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96GG9-1",
                "protein_name": "DCN1-like protein 1",
                "gene_name": "DCUN1D1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXK1-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 15",
                "gene_name": "ASB15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H765-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 8",
                "gene_name": "ASB8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y576-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 1",
                "gene_name": "ASB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96NS5-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 16",
                "gene_name": "ASB16",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXH4-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 11",
                "gene_name": "ASB11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXJ9-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 17",
                "gene_name": "ASB17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXK3-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 13",
                "gene_name": "ASB13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXK4-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 12",
                "gene_name": "ASB12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NWX5-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 6",
                "gene_name": "ASB6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y575-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 3",
                "gene_name": "ASB3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99814-1",
                "protein_name": "Endothelial PAS domain-containing protein 1",
                "gene_name": "EPAS1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BW61-1",
                "protein_name": "DET1- and DDB1-associated protein 1",
                "gene_name": "DDA1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N668-1",
                "protein_name": "COMM domain-containing protein 1",
                "gene_name": "COMMD1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62333-1",
                "protein_name": "26S proteasome regulatory subunit 10B",
                "gene_name": "PSMC6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WWX0-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 5",
                "gene_name": "ASB5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96DX5-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 9",
                "gene_name": "ASB9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UBI1-1",
                "protein_name": "COMM domain-containing protein 3",
                "gene_name": "COMMD3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61201-1",
                "protein_name": "COP9 signalosome complex subunit 2",
                "gene_name": "COPS2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7Z4G1-1",
                "protein_name": "COMM domain-containing protein 6",
                "gene_name": "COMMD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H0A8-1",
                "protein_name": "COMM domain-containing protein 4",
                "gene_name": "COMMD4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y6G5-1",
                "protein_name": "COMM domain-containing protein 10",
                "gene_name": "COMMD10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43242-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 3",
                "gene_name": "PSMD3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H0W5-1",
                "protein_name": "Coiled-coil domain-containing protein 8",
                "gene_name": "CCDC8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86X83-1",
                "protein_name": "COMM domain-containing protein 2",
                "gene_name": "COMMD2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86VX2-1",
                "protein_name": "COMM domain-containing protein 7",
                "gene_name": "COMMD7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9P000-1",
                "protein_name": "COMM domain-containing protein 9",
                "gene_name": "COMMD9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q969H0-1",
                "protein_name": "F-box/WD repeat-containing protein 7",
                "gene_name": "FBXW7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NX08-1",
                "protein_name": "COMM domain-containing protein 8",
                "gene_name": "COMMD8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9GZQ3-1",
                "protein_name": "COMM domain-containing protein 5",
                "gene_name": "COMMD5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5H9S7-1",
                "protein_name": "DDB1- and CUL4-associated factor 17",
                "gene_name": "DCAF17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61962-1",
                "protein_name": "DDB1- and CUL4-associated factor 7",
                "gene_name": "DCAF7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WV16-1",
                "protein_name": "DDB1- and CUL4-associated factor 4",
                "gene_name": "DCAF4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q53GT1-1",
                "protein_name": "Kelch-like protein 22",
                "gene_name": "KLHL22",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5QP82-1",
                "protein_name": "DDB1- and CUL4-associated factor 10",
                "gene_name": "DCAF10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O60662-1",
                "protein_name": "Kelch-like protein 41",
                "gene_name": "KLHL41",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9P2J3-1",
                "protein_name": "Kelch-like protein 9",
                "gene_name": "KLHL9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WWI1-1",
                "protein_name": "LIM domain only protein 7",
                "gene_name": "LMO7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NVR0-1",
                "protein_name": "Kelch-like protein 11",
                "gene_name": "KLHL11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9P2N7-1",
                "protein_name": "Kelch-like protein 13",
                "gene_name": "KLHL13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49721-1",
                "protein_name": "Proteasome subunit beta type-2",
                "gene_name": "PSMB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P20618-1",
                "protein_name": "Proteasome subunit beta type-1",
                "gene_name": "PSMB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15205-1",
                "protein_name": "Ubiquitin D",
                "gene_name": "UBD",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q16236-1",
                "protein_name": "Nuclear factor erythroid 2-related factor 2",
                "gene_name": "NFE2L2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96PQ7-1",
                "protein_name": "Kelch-like protein 5",
                "gene_name": "KLHL5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P15374-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase isozyme L3",
                "gene_name": "UCHL3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NYS7-1",
                "protein_name": "WD repeat and SOCS box-containing protein 2",
                "gene_name": "WSB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y6I7-1",
                "protein_name": "WD repeat and SOCS box-containing protein 1",
                "gene_name": "WSB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H9Q2-1",
                "protein_name": "COP9 signalosome complex subunit 7b",
                "gene_name": "COPS7B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92466-1",
                "protein_name": "DNA damage-binding protein 2",
                "gene_name": "DDB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q14999-1",
                "protein_name": "Cullin-7",
                "gene_name": "CUL7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O94888-1",
                "protein_name": "UBX domain-containing protein 7",
                "gene_name": "UBXN7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13098-4",
                "protein_name": "COP9 signalosome complex subunit 1",
                "gene_name": "GPS1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BT78-1",
                "protein_name": "COP9 signalosome complex subunit 4",
                "gene_name": "COPS4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62877-1",
                "protein_name": "E3 ubiquitin-protein ligase RBX1",
                "gene_name": "RBX1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15843-1",
                "protein_name": "Ubiquitin-like protein NEDD8",
                "gene_name": "NEDD8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61081-1",
                "protein_name": "NEDD8-conjugating enzyme Ubc12",
                "gene_name": "UBE2M",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28070-1",
                "protein_name": "Proteasome subunit beta type-4",
                "gene_name": "PSMB4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86V97-1",
                "protein_name": "Kelch repeat and BTB domain-containing protein 6",
                "gene_name": "KBTBD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WVZ9-1",
                "protein_name": "Kelch repeat and BTB domain-containing protein 7",
                "gene_name": "KBTBD7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NRJ4-1",
                "protein_name": "Tubby-related protein 4",
                "gene_name": "TULP4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61964-1",
                "protein_name": "WD repeat-containing protein 5",
                "gene_name": "WDR5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P55072-1",
                "protein_name": "Transitional endoplasmic reticulum ATPase",
                "gene_name": "VCP",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13618-1",
                "protein_name": "Cullin-3",
                "gene_name": "CUL3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25786-1",
                "protein_name": "Proteasome subunit alpha type-1",
                "gene_name": "PSMA1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NHY2-1",
                "protein_name": "E3 ubiquitin-protein ligase COP1",
                "gene_name": "COP1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7L5N1-1",
                "protein_name": "COP9 signalosome complex subunit 6",
                "gene_name": "COPS6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P40337-1",
                "protein_name": "von Hippel-Lindau disease tumor suppressor",
                "gene_name": "VHL",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5TAQ9-1",
                "protein_name": "DDB1- and CUL4-associated factor 8",
                "gene_name": "DCAF8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96BD6-1",
                "protein_name": "SPRY domain-containing SOCS box protein 1",
                "gene_name": "SPSB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5JTC6-1",
                "protein_name": "APC membrane recruitment protein 1",
                "gene_name": "AMER1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P17980-1",
                "protein_name": "26S proteasome regulatory subunit 6A",
                "gene_name": "PSMC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99619-1",
                "protein_name": "SPRY domain-containing SOCS box protein 2",
                "gene_name": "SPSB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O60826-1",
                "protein_name": "Coiled-coil domain-containing protein 22",
                "gene_name": "CCDC22",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NC69-1",
                "protein_name": "BTB/POZ domain-containing protein KCTD6",
                "gene_name": "KCTD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y297-1",
                "protein_name": "F-box/WD repeat-containing protein 1A",
                "gene_name": "BTRC",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O14544-1",
                "protein_name": "Suppressor of cytokine signaling 6",
                "gene_name": "SOCS6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKB1-1",
                "protein_name": "F-box/WD repeat-containing protein 11",
                "gene_name": "FBXW11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25788-1",
                "protein_name": "Proteasome subunit alpha type-3",
                "gene_name": "PSMA3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8IWE4-1",
                "protein_name": "DCN1-like protein 3",
                "gene_name": "DCUN1D3",
                "tax_name": "Human"
            },
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    {
        "title": "Phosphorylation at serine 75 is required for UV-mediated degradation of human Cdc25A phosphatase at the S-phase checkpoint.",
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                "tax_name": "Human"
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                "uniprot_canonical_ac": "Q15370-1",
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                "tax_name": "Human"
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                "tax_name": "Human"
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                "protein_name": "Endothelial PAS domain-containing protein 1",
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                "protein_name": "26S proteasome regulatory subunit 10B",
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                "protein_name": "Ankyrin repeat and SOCS box protein 5",
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                "tax_name": "Human"
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                "protein_name": "COP9 signalosome complex subunit 2",
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                "tax_name": "Human"
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                "tax_name": "Human"
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                "uniprot_canonical_ac": "O43242-1",
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                "uniprot_canonical_ac": "Q9H0W5-1",
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                "tax_name": "Human"
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                "uniprot_canonical_ac": "Q9NX08-1",
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                "tax_name": "Human"
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                "protein_name": "COMM domain-containing protein 5",
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                "tax_name": "Human"
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                "uniprot_canonical_ac": "P61962-1",
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                "uniprot_canonical_ac": "Q8WV16-1",
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                "tax_name": "Human"
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                "uniprot_canonical_ac": "Q5QP82-1",
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                "gene_name": "DCAF10",
                "tax_name": "Human"
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                "uniprot_canonical_ac": "O60662-1",
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                "protein_name": "Kelch-like protein 9",
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                "uniprot_canonical_ac": "Q8WWI1-1",
                "protein_name": "LIM domain only protein 7",
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                "tax_name": "Human"
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                "uniprot_canonical_ac": "P49721-1",
                "protein_name": "Proteasome subunit beta type-2",
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                "uniprot_canonical_ac": "P20618-1",
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                "protein_name": "Ubiquitin D",
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                "protein_name": "Nuclear factor erythroid 2-related factor 2",
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                "protein_name": "Ubiquitin carboxyl-terminal hydrolase isozyme L3",
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                "uniprot_canonical_ac": "Q9Y6I7-1",
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                "protein_name": "E3 ubiquitin-protein ligase RBX1",
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                "uniprot_canonical_ac": "P40337-1",
                "protein_name": "von Hippel-Lindau disease tumor suppressor",
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                "tax_name": "Human"
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            {
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                "protein_name": "APC membrane recruitment protein 1",
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                "protein_name": "26S proteasome regulatory subunit 6A",
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                "uniprot_canonical_ac": "Q99619-1",
                "protein_name": "SPRY domain-containing SOCS box protein 2",
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            {
                "uniprot_canonical_ac": "O60826-1",
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                "uniprot_canonical_ac": "Q8NC69-1",
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                "tax_name": "Human"
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                "uniprot_canonical_ac": "Q9Y297-1",
                "protein_name": "F-box/WD repeat-containing protein 1A",
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                "tax_name": "Human"
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                "uniprot_canonical_ac": "O14544-1",
                "protein_name": "Suppressor of cytokine signaling 6",
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                "uniprot_canonical_ac": "Q9UKB1-1",
                "protein_name": "F-box/WD repeat-containing protein 11",
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                "tax_name": "Human"
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            {
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                "protein_name": "Proteasome subunit alpha type-3",
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                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "Q8IWE4-1",
                "protein_name": "DCN1-like protein 3",
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                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "Q9UH77-1",
                "protein_name": "Kelch-like protein 3",
                "gene_name": "KLHL3",
                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "Q969P5-1",
                "protein_name": "F-box only protein 32",
                "gene_name": "FBXO32",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y3I1-1",
                "protein_name": "F-box only protein 7",
                "gene_name": "FBXO7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H469-1",
                "protein_name": "F-box/LRR-repeat protein 15",
                "gene_name": "FBXL15",
                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "Q96CD0-1",
                "protein_name": "F-box/LRR-repeat protein 8",
                "gene_name": "FBXL8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NEE6-1",
                "protein_name": "F-box and leucine-rich repeat protein 13",
                "gene_name": "FBXL13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKT7-1",
                "protein_name": "F-box/LRR-repeat protein 3",
                "gene_name": "FBXL3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96EF6-1",
                "protein_name": "F-box only protein 17",
                "gene_name": "FBXO17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UK22-1",
                "protein_name": "F-box only protein 2",
                "gene_name": "FBXO2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P57775-1",
                "protein_name": "F-box/WD repeat-containing protein 4",
                "gene_name": "FBXW4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N1E6-1",
                "protein_name": "F-box/LRR-repeat protein 14",
                "gene_name": "FBXL14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96ME1-4",
                "protein_name": "F-box/LRR-repeat protein 18",
                "gene_name": "FBXL18",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UJT9-1",
                "protein_name": "F-box/LRR-repeat protein 7",
                "gene_name": "FBXL7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKT6-1",
                "protein_name": "Putative F-box/LRR-repeat protein 21",
                "gene_name": "FBXL21P",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O14543-1",
                "protein_name": "Suppressor of cytokine signaling 3",
                "gene_name": "SOCS3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N5D0-1",
                "protein_name": "WD and tetratricopeptide repeats protein 1",
                "gene_name": "WDTC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13501-1",
                "protein_name": "Sequestosome-1",
                "gene_name": "SQSTM1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q969U6-1",
                "protein_name": "F-box/WD repeat-containing protein 5",
                "gene_name": "FBXW5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86XK2-1",
                "protein_name": "F-box only protein 11",
                "gene_name": "FBXO11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P60900-1",
                "protein_name": "Proteasome subunit alpha type-6",
                "gene_name": "PSMA6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62979-1",
                "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein",
                "gene_name": "RPS27A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86YC2-1",
                "protein_name": "Partner and localizer of BRCA2",
                "gene_name": "PALB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H4M3-1",
                "protein_name": "F-box only protein 44",
                "gene_name": "FBXO44",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96KE9-3",
                "protein_name": "BTB/POZ domain-containing protein 6",
                "gene_name": "BTBD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92905-1",
                "protein_name": "COP9 signalosome complex subunit 5",
                "gene_name": "COPS5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13617-1",
                "protein_name": "Cullin-2",
                "gene_name": "CUL2",
                "tax_name": "Human"
            },
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    {
        "title": "Prophase destruction of Emi1 by the SCF(betaTrCP/Slimb) ubiquitin ligase activates the anaphase promoting complex to allow progression beyond prometaphase.",
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        "authors": "Margottin-Goguet F, Hsu JY, Loktev A, Hsieh HM, Reimann JD, Jackson PK",
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    {
        "title": "Regulation of the NEDD8 conjugation system by a splicing variant, NUB1L.",
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                "uniprot_canonical_ac": "Q15291-1",
                "protein_name": "Retinoblastoma-binding protein 5",
                "gene_name": "RBBP5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6ZVZ8-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 18",
                "gene_name": "ASB18",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TAT6-1",
                "protein_name": "Nuclear protein localization protein 4 homolog",
                "gene_name": "NPLOC4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92890-2",
                "protein_name": "Ubiquitin recognition factor in ER-associated degradation protein 1",
                "gene_name": "UFD1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P41002-1",
                "protein_name": "Cyclin-F",
                "gene_name": "CCNF",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q05516-1",
                "protein_name": "Zinc finger and BTB domain-containing protein 16",
                "gene_name": "ZBTB16",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15369-1",
                "protein_name": "Elongin-C",
                "gene_name": "ELOC",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8IWT3-1",
                "protein_name": "Cullin-9",
                "gene_name": "CUL9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TBC4-1",
                "protein_name": "NEDD8-activating enzyme E1 catalytic subunit",
                "gene_name": "UBA3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13216-1",
                "protein_name": "DNA excision repair protein ERCC-8",
                "gene_name": "ERCC8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62195-1",
                "protein_name": "26S proteasome regulatory subunit 8",
                "gene_name": "PSMC5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q16576-1",
                "protein_name": "Histone-binding protein RBBP7",
                "gene_name": "RBBP7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NI29-1",
                "protein_name": "F-box only protein 27",
                "gene_name": "FBXO27",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6P050-1",
                "protein_name": "F-box and leucine-rich protein 22",
                "gene_name": "FBXL22",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NEZ5-1",
                "protein_name": "F-box only protein 22",
                "gene_name": "FBXO22",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NRD1-1",
                "protein_name": "F-box only protein 6",
                "gene_name": "FBXO6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5XUX1-3",
                "protein_name": "F-box/WD repeat-containing protein 9",
                "gene_name": "FBXW9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N3Y1-1",
                "protein_name": "F-box/WD repeat-containing protein 8",
                "gene_name": "FBXW8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UK97-1",
                "protein_name": "F-box only protein 9",
                "gene_name": "FBXO9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKA1-1",
                "protein_name": "F-box/LRR-repeat protein 5",
                "gene_name": "FBXL5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKA2-1",
                "protein_name": "F-box/LRR-repeat protein 4",
                "gene_name": "FBXL4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6PCT2-1",
                "protein_name": "F-box/LRR-repeat protein 19",
                "gene_name": "FBXL19",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N461-1",
                "protein_name": "F-box/LRR-repeat protein 16",
                "gene_name": "FBXL16",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25789-1",
                "protein_name": "Proteasome subunit alpha type-4",
                "gene_name": "PSMA4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H2C0-1",
                "protein_name": "Gigaxonin",
                "gene_name": "GAN",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15345-2",
                "protein_name": "Leucine-rich repeat-containing protein 41",
                "gene_name": "LRRC41",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96MP8-1",
                "protein_name": "BTB/POZ domain-containing protein KCTD7",
                "gene_name": "KCTD7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9JR72-1",
                "protein_name": "Kelch repeat and BTB domain-containing protein 13",
                "gene_name": "KBTBD13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H0H3-1",
                "protein_name": "Kelch-like protein 25",
                "gene_name": "KLHL25",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UJP4-1",
                "protein_name": "Kelch-like protein 21",
                "gene_name": "KLHL21",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96L50-1",
                "protein_name": "Leucine-rich repeat protein 1",
                "gene_name": "LRR1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62191-1",
                "protein_name": "26S proteasome regulatory subunit 4",
                "gene_name": "PSMC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UBW8-1",
                "protein_name": "COP9 signalosome complex subunit 7a",
                "gene_name": "COPS7A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99627-1",
                "protein_name": "COP9 signalosome complex subunit 8",
                "gene_name": "COPS8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O75147-3",
                "protein_name": "Obscurin-like protein 1",
                "gene_name": "OBSL1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49720-1",
                "protein_name": "Proteasome subunit beta type-3",
                "gene_name": "PSMB3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99460-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 1",
                "gene_name": "PSMD1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UNM6-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 13",
                "gene_name": "PSMD13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P51665-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 7",
                "gene_name": "PSMD7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NSE2-1",
                "protein_name": "Cytokine-inducible SH2-containing protein",
                "gene_name": "CISH",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13309-1",
                "protein_name": "S-phase kinase-associated protein 2",
                "gene_name": "SKP2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BR09-1",
                "protein_name": "Neuralized-like protein 2",
                "gene_name": "NEURL2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28074-1",
                "protein_name": "Proteasome subunit beta type-5",
                "gene_name": "PSMB5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P35998-1",
                "protein_name": "26S proteasome regulatory subunit 7",
                "gene_name": "PSMC2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P43686-1",
                "protein_name": "26S proteasome regulatory subunit 6B",
                "gene_name": "PSMC4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99436-1",
                "protein_name": "Proteasome subunit beta type-7",
                "gene_name": "PSMB7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15392-1",
                "protein_name": "Baculoviral IAP repeat-containing protein 5",
                "gene_name": "BIRC5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5XUX0-1",
                "protein_name": "F-box only protein 31",
                "gene_name": "FBXO31",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15370-1",
                "protein_name": "Elongin-B",
                "gene_name": "ELOB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61077-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 D3",
                "gene_name": "UBE2D3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P51668-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 D1",
                "gene_name": "UBE2D1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O14508-1",
                "protein_name": "Suppressor of cytokine signaling 2",
                "gene_name": "SOCS2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q16531-1",
                "protein_name": "DNA damage-binding protein 1",
                "gene_name": "DDB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXI3-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 10",
                "gene_name": "ASB10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13200-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 2",
                "gene_name": "PSMD2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96GG9-1",
                "protein_name": "DCN1-like protein 1",
                "gene_name": "DCUN1D1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXK1-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 15",
                "gene_name": "ASB15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H765-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 8",
                "gene_name": "ASB8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y576-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 1",
                "gene_name": "ASB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96NS5-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 16",
                "gene_name": "ASB16",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXH4-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 11",
                "gene_name": "ASB11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXJ9-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 17",
                "gene_name": "ASB17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXK3-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 13",
                "gene_name": "ASB13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXK4-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 12",
                "gene_name": "ASB12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NWX5-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 6",
                "gene_name": "ASB6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y575-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 3",
                "gene_name": "ASB3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99814-1",
                "protein_name": "Endothelial PAS domain-containing protein 1",
                "gene_name": "EPAS1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BW61-1",
                "protein_name": "DET1- and DDB1-associated protein 1",
                "gene_name": "DDA1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N668-1",
                "protein_name": "COMM domain-containing protein 1",
                "gene_name": "COMMD1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62333-1",
                "protein_name": "26S proteasome regulatory subunit 10B",
                "gene_name": "PSMC6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WWX0-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 5",
                "gene_name": "ASB5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96DX5-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 9",
                "gene_name": "ASB9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UBI1-1",
                "protein_name": "COMM domain-containing protein 3",
                "gene_name": "COMMD3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61201-1",
                "protein_name": "COP9 signalosome complex subunit 2",
                "gene_name": "COPS2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7Z4G1-1",
                "protein_name": "COMM domain-containing protein 6",
                "gene_name": "COMMD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H0A8-1",
                "protein_name": "COMM domain-containing protein 4",
                "gene_name": "COMMD4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y6G5-1",
                "protein_name": "COMM domain-containing protein 10",
                "gene_name": "COMMD10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43242-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 3",
                "gene_name": "PSMD3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H0W5-1",
                "protein_name": "Coiled-coil domain-containing protein 8",
                "gene_name": "CCDC8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86X83-1",
                "protein_name": "COMM domain-containing protein 2",
                "gene_name": "COMMD2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86VX2-1",
                "protein_name": "COMM domain-containing protein 7",
                "gene_name": "COMMD7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9P000-1",
                "protein_name": "COMM domain-containing protein 9",
                "gene_name": "COMMD9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q969H0-1",
                "protein_name": "F-box/WD repeat-containing protein 7",
                "gene_name": "FBXW7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NX08-1",
                "protein_name": "COMM domain-containing protein 8",
                "gene_name": "COMMD8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9GZQ3-1",
                "protein_name": "COMM domain-containing protein 5",
                "gene_name": "COMMD5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5H9S7-1",
                "protein_name": "DDB1- and CUL4-associated factor 17",
                "gene_name": "DCAF17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61962-1",
                "protein_name": "DDB1- and CUL4-associated factor 7",
                "gene_name": "DCAF7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WV16-1",
                "protein_name": "DDB1- and CUL4-associated factor 4",
                "gene_name": "DCAF4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q53GT1-1",
                "protein_name": "Kelch-like protein 22",
                "gene_name": "KLHL22",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5QP82-1",
                "protein_name": "DDB1- and CUL4-associated factor 10",
                "gene_name": "DCAF10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O60662-1",
                "protein_name": "Kelch-like protein 41",
                "gene_name": "KLHL41",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9P2J3-1",
                "protein_name": "Kelch-like protein 9",
                "gene_name": "KLHL9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WWI1-1",
                "protein_name": "LIM domain only protein 7",
                "gene_name": "LMO7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P54729-1",
                "protein_name": "NEDD8 ultimate buster 1",
                "gene_name": "Nub1",
                "tax_name": "Mouse"
            },
            {
                "uniprot_canonical_ac": "Q9NVR0-1",
                "protein_name": "Kelch-like protein 11",
                "gene_name": "KLHL11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9P2N7-1",
                "protein_name": "Kelch-like protein 13",
                "gene_name": "KLHL13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49721-1",
                "protein_name": "Proteasome subunit beta type-2",
                "gene_name": "PSMB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P20618-1",
                "protein_name": "Proteasome subunit beta type-1",
                "gene_name": "PSMB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15205-1",
                "protein_name": "Ubiquitin D",
                "gene_name": "UBD",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q16236-1",
                "protein_name": "Nuclear factor erythroid 2-related factor 2",
                "gene_name": "NFE2L2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96PQ7-1",
                "protein_name": "Kelch-like protein 5",
                "gene_name": "KLHL5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P15374-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase isozyme L3",
                "gene_name": "UCHL3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NYS7-1",
                "protein_name": "WD repeat and SOCS box-containing protein 2",
                "gene_name": "WSB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y6I7-1",
                "protein_name": "WD repeat and SOCS box-containing protein 1",
                "gene_name": "WSB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H9Q2-1",
                "protein_name": "COP9 signalosome complex subunit 7b",
                "gene_name": "COPS7B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92466-1",
                "protein_name": "DNA damage-binding protein 2",
                "gene_name": "DDB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q14999-1",
                "protein_name": "Cullin-7",
                "gene_name": "CUL7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O94888-1",
                "protein_name": "UBX domain-containing protein 7",
                "gene_name": "UBXN7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13098-4",
                "protein_name": "COP9 signalosome complex subunit 1",
                "gene_name": "GPS1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BT78-1",
                "protein_name": "COP9 signalosome complex subunit 4",
                "gene_name": "COPS4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62877-1",
                "protein_name": "E3 ubiquitin-protein ligase RBX1",
                "gene_name": "RBX1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15843-1",
                "protein_name": "Ubiquitin-like protein NEDD8",
                "gene_name": "NEDD8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61081-1",
                "protein_name": "NEDD8-conjugating enzyme Ubc12",
                "gene_name": "UBE2M",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28070-1",
                "protein_name": "Proteasome subunit beta type-4",
                "gene_name": "PSMB4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86V97-1",
                "protein_name": "Kelch repeat and BTB domain-containing protein 6",
                "gene_name": "KBTBD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WVZ9-1",
                "protein_name": "Kelch repeat and BTB domain-containing protein 7",
                "gene_name": "KBTBD7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NRJ4-1",
                "protein_name": "Tubby-related protein 4",
                "gene_name": "TULP4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y5A7-1",
                "protein_name": "NEDD8 ultimate buster 1",
                "gene_name": "NUB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61964-1",
                "protein_name": "WD repeat-containing protein 5",
                "gene_name": "WDR5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P55072-1",
                "protein_name": "Transitional endoplasmic reticulum ATPase",
                "gene_name": "VCP",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13618-1",
                "protein_name": "Cullin-3",
                "gene_name": "CUL3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25786-1",
                "protein_name": "Proteasome subunit alpha type-1",
                "gene_name": "PSMA1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NHY2-1",
                "protein_name": "E3 ubiquitin-protein ligase COP1",
                "gene_name": "COP1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7L5N1-1",
                "protein_name": "COP9 signalosome complex subunit 6",
                "gene_name": "COPS6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P40337-1",
                "protein_name": "von Hippel-Lindau disease tumor suppressor",
                "gene_name": "VHL",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5TAQ9-1",
                "protein_name": "DDB1- and CUL4-associated factor 8",
                "gene_name": "DCAF8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96BD6-1",
                "protein_name": "SPRY domain-containing SOCS box protein 1",
                "gene_name": "SPSB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5JTC6-1",
                "protein_name": "APC membrane recruitment protein 1",
                "gene_name": "AMER1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P17980-1",
                "protein_name": "26S proteasome regulatory subunit 6A",
                "gene_name": "PSMC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99619-1",
                "protein_name": "SPRY domain-containing SOCS box protein 2",
                "gene_name": "SPSB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O60826-1",
                "protein_name": "Coiled-coil domain-containing protein 22",
                "gene_name": "CCDC22",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NC69-1",
                "protein_name": "BTB/POZ domain-containing protein KCTD6",
                "gene_name": "KCTD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y297-1",
                "protein_name": "F-box/WD repeat-containing protein 1A",
                "gene_name": "BTRC",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O14544-1",
                "protein_name": "Suppressor of cytokine signaling 6",
                "gene_name": "SOCS6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKB1-1",
                "protein_name": "F-box/WD repeat-containing protein 11",
                "gene_name": "FBXW11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25788-1",
                "protein_name": "Proteasome subunit alpha type-3",
                "gene_name": "PSMA3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8IWE4-1",
                "protein_name": "DCN1-like protein 3",
                "gene_name": "DCUN1D3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UH77-1",
                "protein_name": "Kelch-like protein 3",
                "gene_name": "KLHL3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q969P5-1",
                "protein_name": "F-box only protein 32",
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                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y3I1-1",
                "protein_name": "F-box only protein 7",
                "gene_name": "FBXO7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H469-1",
                "protein_name": "F-box/LRR-repeat protein 15",
                "gene_name": "FBXL15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96CD0-1",
                "protein_name": "F-box/LRR-repeat protein 8",
                "gene_name": "FBXL8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NEE6-1",
                "protein_name": "F-box and leucine-rich repeat protein 13",
                "gene_name": "FBXL13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKT7-1",
                "protein_name": "F-box/LRR-repeat protein 3",
                "gene_name": "FBXL3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96EF6-1",
                "protein_name": "F-box only protein 17",
                "gene_name": "FBXO17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UK22-1",
                "protein_name": "F-box only protein 2",
                "gene_name": "FBXO2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P57775-1",
                "protein_name": "F-box/WD repeat-containing protein 4",
                "gene_name": "FBXW4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N1E6-1",
                "protein_name": "F-box/LRR-repeat protein 14",
                "gene_name": "FBXL14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96ME1-4",
                "protein_name": "F-box/LRR-repeat protein 18",
                "gene_name": "FBXL18",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UJT9-1",
                "protein_name": "F-box/LRR-repeat protein 7",
                "gene_name": "FBXL7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKT6-1",
                "protein_name": "Putative F-box/LRR-repeat protein 21",
                "gene_name": "FBXL21P",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O14543-1",
                "protein_name": "Suppressor of cytokine signaling 3",
                "gene_name": "SOCS3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N5D0-1",
                "protein_name": "WD and tetratricopeptide repeats protein 1",
                "gene_name": "WDTC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13501-1",
                "protein_name": "Sequestosome-1",
                "gene_name": "SQSTM1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q969U6-1",
                "protein_name": "F-box/WD repeat-containing protein 5",
                "gene_name": "FBXW5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86XK2-1",
                "protein_name": "F-box only protein 11",
                "gene_name": "FBXO11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P60900-1",
                "protein_name": "Proteasome subunit alpha type-6",
                "gene_name": "PSMA6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62979-1",
                "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein",
                "gene_name": "RPS27A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86YC2-1",
                "protein_name": "Partner and localizer of BRCA2",
                "gene_name": "PALB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H4M3-1",
                "protein_name": "F-box only protein 44",
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                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96KE9-3",
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                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92905-1",
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            {
                "uniprot_canonical_ac": "Q13617-1",
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                "tax_name": "Human"
            },
            {
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                "protein_name": "Cullin-4A",
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                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "Q86VP6-1",
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            {
                "uniprot_canonical_ac": "P62837-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 D2",
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                "tax_name": "Human"
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            {
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                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "Q9H0C5-1",
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            {
                "uniprot_canonical_ac": "Q9NXF7-1",
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                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "Q9Y2N7-1",
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                "tax_name": "Human"
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            {
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            {
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            {
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            {
                "uniprot_canonical_ac": "O00232-1",
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                "tax_name": "Human"
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            {
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                "protein_name": "Proteasome subunit alpha type-2",
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            {
                "uniprot_canonical_ac": "P28066-1",
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            {
                "uniprot_canonical_ac": "Q8NCQ5-1",
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                "tax_name": "Human"
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            {
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                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "Q8TB52-1",
                "protein_name": "F-box only protein 30",
                "gene_name": "FBXO30",
                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "Q96JP0-1",
                "protein_name": "Protein fem-1 homolog C",
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                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "Q9UH90-1",
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            {
                "uniprot_canonical_ac": "Q969M7-1",
                "protein_name": "NEDD8-conjugating enzyme UBE2F",
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            {
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            {
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            {
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            {
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            {
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            {
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            {
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            {
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            {
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            {
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            {
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        ],
        "species": [
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                "name": "Homo sapiens",
                "taxid": 9606,
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                        "url": "https://www.uniprot.org/uniprotkb/O14818"
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                ],
                "common_name": "Human",
                "glygen_name": "Human",
                "reference_species": "Homo sapiens [9606]"
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        ],
        "mutagenesis": [
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                "start_pos": 448,
                "end_pos": 448,
                "sequence_org": "A",
                "sequence_mut": "V",
                "comment": "No effect on NEDD8-binding.",
                "evidence": [
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                        "id": "Q9Y5A7",
                        "url": "https://www.uniprot.org/uniprotkb/Q9Y5A7"
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                "sequence_org": "L",
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                "comment": "Partial inhibition of NEDD8-binding.",
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                        "url": "https://www.uniprot.org/uniprotkb/Q9Y5A7"
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                "uniprot_canonical_ac": "Q9Y5A7-1"
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                "sequence_org": "L",
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                "comment": "Partial inhibition of NEDD8-binding.",
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                "uniprot_canonical_ac": "Q9Y5A7-1"
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            {
                "start_pos": 468,
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                "sequence_org": "L",
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                "comment": "Partial inhibition of NEDD8-binding.",
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    {
        "title": "Characterization of Pellino2, a substrate of IRAK1 and IRAK4.",
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        "date": "2003",
        "authors": "Strelow A, Kollewe C, Wesche H",
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    {
        "title": "HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1alpha in normoxia.",
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    {
        "title": "CYLD is a deubiquitinating enzyme that negatively regulates NF-kappaB activation by TNFR family members.",
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                "uniprot_canonical_ac": "Q9NQC7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase CYLD",
                "gene_name": "CYLD",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O95786-1",
                "protein_name": "Antiviral innate immune response receptor RIG-I",
                "gene_name": "DDX58; RIGI",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y265-1",
                "protein_name": "RuvB-like 1",
                "gene_name": "RUVBL1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UK80-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 21",
                "gene_name": "USP21",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NZL9-1",
                "protein_name": "Methionine adenosyltransferase 2 subunit beta",
                "gene_name": "MAT2B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92830-1",
                "protein_name": "Histone acetyltransferase KAT2A",
                "gene_name": "KAT2A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49721-1",
                "protein_name": "Proteasome subunit beta type-2",
                "gene_name": "PSMB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P20618-1",
                "protein_name": "Proteasome subunit beta type-1",
                "gene_name": "PSMB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43255-1",
                "protein_name": "E3 ubiquitin-protein ligase SIAH2",
                "gene_name": "SIAH2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43318-1",
                "protein_name": "Mitogen-activated protein kinase kinase kinase 7",
                "gene_name": "MAP3K7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8IXI2-1",
                "protein_name": "Mitochondrial Rho GTPase 1",
                "gene_name": "RHOT1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P54578-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 14",
                "gene_name": "USP14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86TJ2-1",
                "protein_name": "Transcriptional adapter 2-beta",
                "gene_name": "TADA2B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92466-1",
                "protein_name": "DNA damage-binding protein 2",
                "gene_name": "DDB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28070-1",
                "protein_name": "Proteasome subunit beta type-4",
                "gene_name": "PSMB4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UMW8-1",
                "protein_name": "Ubl carboxyl-terminal hydrolase 18",
                "gene_name": "USP18",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9JJH3-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 10",
                "gene_name": "USP17L10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "A6NCW7-1",
                "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 4",
                "gene_name": "USP17L4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P45880-3",
                "protein_name": "Non-selective voltage-gated ion channel VDAC2",
                "gene_name": "VDAC2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P06746-1",
                "protein_name": "DNA polymerase beta",
                "gene_name": "POLB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P07550-1",
                "protein_name": "Beta-2 adrenergic receptor",
                "gene_name": "ADRB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0C0S8-1",
                "protein_name": "Histone H2A type 1",
                "gene_name": "H2AC11; H2AC13; H2AC15; H2AC16; H2AC17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P36897-1",
                "protein_name": "TGF-beta receptor type-1",
                "gene_name": "TGFBR1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15105-1",
                "protein_name": "SMAD family member 7",
                "gene_name": "SMAD7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P32121-1",
                "protein_name": "Beta-arrestin-2",
                "gene_name": "ARRB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H2K2-1",
                "protein_name": "Poly [ADP-ribose] polymerase tankyrase-2",
                "gene_name": "TNKS2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25786-1",
                "protein_name": "Proteasome subunit alpha type-1",
                "gene_name": "PSMA1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49407-1",
                "protein_name": "Beta-arrestin-1",
                "gene_name": "ARRB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P98177-1",
                "protein_name": "Forkhead box protein O4",
                "gene_name": "FOXO4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P17980-1",
                "protein_name": "26S proteasome regulatory subunit 6A",
                "gene_name": "PSMC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y2T1-1",
                "protein_name": "Axin-2",
                "gene_name": "AXIN2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P23771-1",
                "protein_name": "Trans-acting T-cell-specific transcription factor GATA-3",
                "gene_name": "GATA3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q16778-1",
                "protein_name": "Histone H2B type 2-E",
                "gene_name": "H2BC21",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15169-1",
                "protein_name": "Axin-1",
                "gene_name": "AXIN1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62807-1",
                "protein_name": "Histone H2B type 1-C/E/F/G/I",
                "gene_name": "H2BC10; H2BC4; H2BC6; H2BC7; H2BC8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P84022-1",
                "protein_name": "SMAD family member 3",
                "gene_name": "SMAD3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15797-1",
                "protein_name": "SMAD family member 1",
                "gene_name": "SMAD1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25788-1",
                "protein_name": "Proteasome subunit alpha type-3",
                "gene_name": "PSMA3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q14694-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 10",
                "gene_name": "USP10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9HAU4-1",
                "protein_name": "E3 ubiquitin-protein ligase SMURF2",
                "gene_name": "SMURF2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H0E7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 44",
                "gene_name": "USP44",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86UV5-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 48",
                "gene_name": "USP48",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6RBQ6-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 17",
                "gene_name": "USP17L17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q70CQ3-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 30",
                "gene_name": "USP30",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TEY7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 33",
                "gene_name": "USP33",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6RCP7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 19",
                "gene_name": "USP17L19",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9JLJ4-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 13",
                "gene_name": "USP17L13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6RJB6-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 20",
                "gene_name": "USP17L20",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15388-1",
                "protein_name": "Mitochondrial import receptor subunit TOM20 homolog",
                "gene_name": "TOMM20",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "A6NCW0-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 3",
                "gene_name": "USP17L3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "A8MUK1-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 5",
                "gene_name": "USP17L5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9J2P7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 15",
                "gene_name": "USP17L15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9JVI0-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 11",
                "gene_name": "USP17L11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6R9N7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 18",
                "gene_name": "USP17L18",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6RA61-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 22",
                "gene_name": "USP17L22",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0C7I0-1",
                "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 8",
                "gene_name": "USP17L8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6R901-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 21",
                "gene_name": "USP17L21",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q0WX57-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 24",
                "gene_name": "USP17L24; USP17L25; USP17L26; USP17L27; USP17L28; USP17L29; USP17L30",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P60900-1",
                "protein_name": "Proteasome subunit alpha type-6",
                "gene_name": "PSMA6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13490-1",
                "protein_name": "Baculoviral IAP repeat-containing protein 2",
                "gene_name": "BIRC2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62979-1",
                "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein",
                "gene_name": "RPS27A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P60484-1",
                "protein_name": "Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN",
                "gene_name": "PTEN",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P51784-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 11",
                "gene_name": "USP11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H7L9-1",
                "protein_name": "Sin3 histone deacetylase corepressor complex component SDS3",
                "gene_name": "SUDS3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01106-2",
                "protein_name": "Myc proto-oncogene protein",
                "gene_name": "MYC",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P21796-1",
                "protein_name": "Non-selective voltage-gated ion channel VDAC1",
                "gene_name": "VDAC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y4A5-1",
                "protein_name": "Transformation/transcription domain-associated protein",
                "gene_name": "TRRAP",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96FW1-1",
                "protein_name": "Ubiquitin thioesterase OTUB1",
                "gene_name": "OTUB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P13569-1",
                "protein_name": "Cystic fibrosis transmembrane conductance regulator",
                "gene_name": "CFTR",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13489-1",
                "protein_name": "Baculoviral IAP repeat-containing protein 3",
                "gene_name": "BIRC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5QNW6-1",
                "protein_name": "Histone H2B type 2-F",
                "gene_name": "H2BC18",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P33778-1",
                "protein_name": "Histone H2B type 1-B",
                "gene_name": "H2BC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P58876-1",
                "protein_name": "Histone H2B type 1-D",
                "gene_name": "H2BC5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96A08-1",
                "protein_name": "Histone H2B type 1-A",
                "gene_name": "H2BC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P23527-1",
                "protein_name": "Histone H2B type 1-O",
                "gene_name": "H2BC17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BYX4-1",
                "protein_name": "Interferon-induced helicase C domain-containing protein 1",
                "gene_name": "IFIH1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UHP3-2",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 25",
                "gene_name": "USP25",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H9J4-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 42",
                "gene_name": "USP42",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P48556-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 8",
                "gene_name": "PSMD8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15008-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 6",
                "gene_name": "PSMD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28072-1",
                "protein_name": "Proteasome subunit beta type-6",
                "gene_name": "PSMB6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O00232-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 12",
                "gene_name": "PSMD12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25787-1",
                "protein_name": "Proteasome subunit alpha type-2",
                "gene_name": "PSMA2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28066-1",
                "protein_name": "Proteasome subunit alpha type-5",
                "gene_name": "PSMA5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5XPI4-1",
                "protein_name": "E3 ubiquitin-protein ligase RNF123",
                "gene_name": "RNF123",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q93008-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 9X",
                "gene_name": "USP9X",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O60814-1",
                "protein_name": "Histone H2B type 1-K",
                "gene_name": "H2BC12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q93077-1",
                "protein_name": "Histone H2A type 1-C",
                "gene_name": "H2AC6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q93079-1",
                "protein_name": "Histone H2B type 1-H",
                "gene_name": "H2BC9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96KK5-1",
                "protein_name": "Histone H2A type 1-H",
                "gene_name": "H2AC12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99879-1",
                "protein_name": "Histone H2B type 1-M",
                "gene_name": "H2BC14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y6I4-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 3",
                "gene_name": "USP3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96RU2-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 28",
                "gene_name": "USP28",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q70CQ2-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 34",
                "gene_name": "USP34",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O94826-1",
                "protein_name": "Mitochondrial import receptor subunit TOM70",
                "gene_name": "TOMM70",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86T82-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 37",
                "gene_name": "USP37",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BXU7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 26",
                "gene_name": "USP26",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6R6M4-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17",
                "gene_name": "USP17L2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7RTZ2-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 1",
                "gene_name": "USP17L1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9HBM6-1",
                "protein_name": "Transcription initiation factor TFIID subunit 9B",
                "gene_name": "TAF9B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y277-1",
                "protein_name": "Non-selective voltage-gated ion channel VDAC3",
                "gene_name": "VDAC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O75317-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 12",
                "gene_name": "USP12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9JPN9-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 12",
                "gene_name": "USP17L12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O75528-1",
                "protein_name": "Transcriptional adapter 3",
                "gene_name": "TADA3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q12962-1",
                "protein_name": "Transcription initiation factor TFIID subunit 10",
                "gene_name": "TAF10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y4E8-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 15",
                "gene_name": "USP15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0CG47-1",
                "protein_name": "Polyubiquitin-B",
                "gene_name": "UBB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9HAW4-1",
                "protein_name": "Claspin",
                "gene_name": "CLSPN",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TBZ3-1",
                "protein_name": "WD repeat-containing protein 20",
                "gene_name": "WDR20",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P45974-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 5",
                "gene_name": "USP5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62987-1",
                "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein",
                "gene_name": "UBA52",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O00487-1",
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                "uniprot_canonical_ac": "P28074-1",
                "protein_name": "Proteasome subunit beta type-5",
                "gene_name": "PSMB5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P35998-1",
                "protein_name": "26S proteasome regulatory subunit 7",
                "gene_name": "PSMC2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P43686-1",
                "protein_name": "26S proteasome regulatory subunit 6B",
                "gene_name": "PSMC4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99436-1",
                "protein_name": "Proteasome subunit beta type-7",
                "gene_name": "PSMB7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O14920-1",
                "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit beta",
                "gene_name": "IKBKB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q93009-1",
                "protein_name": "Ubiquitin C-terminal hydrolase 7",
                "gene_name": "USP7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y2K6-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 20",
                "gene_name": "USP20",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q14318-1",
                "protein_name": "Peptidyl-prolyl cis-trans isomerase FKBP8",
                "gene_name": "FKBP8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13200-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 2",
                "gene_name": "PSMD2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96J02-1",
                "protein_name": "E3 ubiquitin-protein ligase Itchy homolog",
                "gene_name": "ITCH",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62333-1",
                "protein_name": "26S proteasome regulatory subunit 10B",
                "gene_name": "PSMC6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P42575-1",
                "protein_name": "Caspase-2",
                "gene_name": "CASP2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49662-1",
                "protein_name": "Caspase-4",
                "gene_name": "CASP4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P78396-1",
                "protein_name": "Cyclin-A1",
                "gene_name": "CCNA1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43303-1",
                "protein_name": "Centriolar coiled-coil protein of 110 kDa",
                "gene_name": "CCP110",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43242-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 3",
                "gene_name": "PSMD3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P14735-1",
                "protein_name": "Insulin-degrading enzyme",
                "gene_name": "IDE",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NQC7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase CYLD",
                "gene_name": "CYLD",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O95786-1",
                "protein_name": "Antiviral innate immune response receptor RIG-I",
                "gene_name": "DDX58; RIGI",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y265-1",
                "protein_name": "RuvB-like 1",
                "gene_name": "RUVBL1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UK80-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 21",
                "gene_name": "USP21",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P53778-1",
                "protein_name": "Mitogen-activated protein kinase 12",
                "gene_name": "MAPK12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NZL9-1",
                "protein_name": "Methionine adenosyltransferase 2 subunit beta",
                "gene_name": "MAT2B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92830-1",
                "protein_name": "Histone acetyltransferase KAT2A",
                "gene_name": "KAT2A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49721-1",
                "protein_name": "Proteasome subunit beta type-2",
                "gene_name": "PSMB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P20618-1",
                "protein_name": "Proteasome subunit beta type-1",
                "gene_name": "PSMB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43255-1",
                "protein_name": "E3 ubiquitin-protein ligase SIAH2",
                "gene_name": "SIAH2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43318-1",
                "protein_name": "Mitogen-activated protein kinase kinase kinase 7",
                "gene_name": "MAP3K7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8IXI2-1",
                "protein_name": "Mitochondrial Rho GTPase 1",
                "gene_name": "RHOT1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P54578-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 14",
                "gene_name": "USP14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86TJ2-1",
                "protein_name": "Transcriptional adapter 2-beta",
                "gene_name": "TADA2B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92466-1",
                "protein_name": "DNA damage-binding protein 2",
                "gene_name": "DDB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28070-1",
                "protein_name": "Proteasome subunit beta type-4",
                "gene_name": "PSMB4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UMW8-1",
                "protein_name": "Ubl carboxyl-terminal hydrolase 18",
                "gene_name": "USP18",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9JJH3-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 10",
                "gene_name": "USP17L10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "A6NCW7-1",
                "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 4",
                "gene_name": "USP17L4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P45880-3",
                "protein_name": "Non-selective voltage-gated ion channel VDAC2",
                "gene_name": "VDAC2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P06746-1",
                "protein_name": "DNA polymerase beta",
                "gene_name": "POLB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P07550-1",
                "protein_name": "Beta-2 adrenergic receptor",
                "gene_name": "ADRB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H257-1",
                "protein_name": "Caspase recruitment domain-containing protein 9",
                "gene_name": "CARD9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0C0S8-1",
                "protein_name": "Histone H2A type 1",
                "gene_name": "H2AC11; H2AC13; H2AC15; H2AC16; H2AC17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P36897-1",
                "protein_name": "TGF-beta receptor type-1",
                "gene_name": "TGFBR1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15105-1",
                "protein_name": "SMAD family member 7",
                "gene_name": "SMAD7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P32121-1",
                "protein_name": "Beta-arrestin-2",
                "gene_name": "ARRB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9HC29-1",
                "protein_name": "Nucleotide-binding oligomerization domain-containing protein 2",
                "gene_name": "NOD2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H2K2-1",
                "protein_name": "Poly [ADP-ribose] polymerase tankyrase-2",
                "gene_name": "TNKS2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25786-1",
                "protein_name": "Proteasome subunit alpha type-1",
                "gene_name": "PSMA1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49407-1",
                "protein_name": "Beta-arrestin-1",
                "gene_name": "ARRB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P98177-1",
                "protein_name": "Forkhead box protein O4",
                "gene_name": "FOXO4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P17980-1",
                "protein_name": "26S proteasome regulatory subunit 6A",
                "gene_name": "PSMC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y2T1-1",
                "protein_name": "Axin-2",
                "gene_name": "AXIN2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P23771-1",
                "protein_name": "Trans-acting T-cell-specific transcription factor GATA-3",
                "gene_name": "GATA3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q16778-1",
                "protein_name": "Histone H2B type 2-E",
                "gene_name": "H2BC21",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15169-1",
                "protein_name": "Axin-1",
                "gene_name": "AXIN1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62807-1",
                "protein_name": "Histone H2B type 1-C/E/F/G/I",
                "gene_name": "H2BC10; H2BC4; H2BC6; H2BC7; H2BC8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P84022-1",
                "protein_name": "SMAD family member 3",
                "gene_name": "SMAD3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15797-1",
                "protein_name": "SMAD family member 1",
                "gene_name": "SMAD1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25788-1",
                "protein_name": "Proteasome subunit alpha type-3",
                "gene_name": "PSMA3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q14790-1",
                "protein_name": "Caspase-8",
                "gene_name": "CASP8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q14694-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 10",
                "gene_name": "USP10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9HAU4-1",
                "protein_name": "E3 ubiquitin-protein ligase SMURF2",
                "gene_name": "SMURF2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H0E7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 44",
                "gene_name": "USP44",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86UV5-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 48",
                "gene_name": "USP48",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6RBQ6-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 17",
                "gene_name": "USP17L17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q70CQ3-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 30",
                "gene_name": "USP30",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TEY7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 33",
                "gene_name": "USP33",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6RCP7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 19",
                "gene_name": "USP17L19",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9JLJ4-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 13",
                "gene_name": "USP17L13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6RJB6-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 20",
                "gene_name": "USP17L20",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15388-1",
                "protein_name": "Mitochondrial import receptor subunit TOM20 homolog",
                "gene_name": "TOMM20",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "A6NCW0-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 3",
                "gene_name": "USP17L3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "A8MUK1-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 5",
                "gene_name": "USP17L5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9J2P7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 15",
                "gene_name": "USP17L15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9JVI0-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 11",
                "gene_name": "USP17L11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6R9N7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 18",
                "gene_name": "USP17L18",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6RA61-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 22",
                "gene_name": "USP17L22",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0C7I0-1",
                "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 8",
                "gene_name": "USP17L8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6R901-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 21",
                "gene_name": "USP17L21",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q0WX57-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 24",
                "gene_name": "USP17L24; USP17L25; USP17L26; USP17L27; USP17L28; USP17L29; USP17L30",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N5C8-1",
                "protein_name": "TGF-beta-activated kinase 1 and MAP3K7-binding protein 3",
                "gene_name": "TAB3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P60900-1",
                "protein_name": "Proteasome subunit alpha type-6",
                "gene_name": "PSMA6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13490-1",
                "protein_name": "Baculoviral IAP repeat-containing protein 2",
                "gene_name": "BIRC2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NYJ8-1",
                "protein_name": "TGF-beta-activated kinase 1 and MAP3K7-binding protein 2",
                "gene_name": "TAB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62979-1",
                "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein",
                "gene_name": "RPS27A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P60484-1",
                "protein_name": "Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN",
                "gene_name": "PTEN",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P51784-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 11",
                "gene_name": "USP11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H7L9-1",
                "protein_name": "Sin3 histone deacetylase corepressor complex component SDS3",
                "gene_name": "SUDS3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01106-2",
                "protein_name": "Myc proto-oncogene protein",
                "gene_name": "MYC",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P21796-1",
                "protein_name": "Non-selective voltage-gated ion channel VDAC1",
                "gene_name": "VDAC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43353-1",
                "protein_name": "Receptor-interacting serine/threonine-protein kinase 2",
                "gene_name": "RIPK2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y4A5-1",
                "protein_name": "Transformation/transcription domain-associated protein",
                "gene_name": "TRRAP",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61088-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 N",
                "gene_name": "UBE2N",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96FW1-1",
                "protein_name": "Ubiquitin thioesterase OTUB1",
                "gene_name": "OTUB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P13569-1",
                "protein_name": "Cystic fibrosis transmembrane conductance regulator",
                "gene_name": "CFTR",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13489-1",
                "protein_name": "Baculoviral IAP repeat-containing protein 3",
                "gene_name": "BIRC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5QNW6-1",
                "protein_name": "Histone H2B type 2-F",
                "gene_name": "H2BC18",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P33778-1",
                "protein_name": "Histone H2B type 1-B",
                "gene_name": "H2BC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P58876-1",
                "protein_name": "Histone H2B type 1-D",
                "gene_name": "H2BC5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96A08-1",
                "protein_name": "Histone H2B type 1-A",
                "gene_name": "H2BC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P23527-1",
                "protein_name": "Histone H2B type 1-O",
                "gene_name": "H2BC17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BYX4-1",
                "protein_name": "Interferon-induced helicase C domain-containing protein 1",
                "gene_name": "IFIH1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UHP3-2",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 25",
                "gene_name": "USP25",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H9J4-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 42",
                "gene_name": "USP42",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P48556-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 8",
                "gene_name": "PSMD8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15008-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 6",
                "gene_name": "PSMD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28072-1",
                "protein_name": "Proteasome subunit beta type-6",
                "gene_name": "PSMB6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O00232-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 12",
                "gene_name": "PSMD12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25787-1",
                "protein_name": "Proteasome subunit alpha type-2",
                "gene_name": "PSMA2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28066-1",
                "protein_name": "Proteasome subunit alpha type-5",
                "gene_name": "PSMA5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5XPI4-1",
                "protein_name": "E3 ubiquitin-protein ligase RNF123",
                "gene_name": "RNF123",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q93008-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 9X",
                "gene_name": "USP9X",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O60814-1",
                "protein_name": "Histone H2B type 1-K",
                "gene_name": "H2BC12",
                "tax_name": "Human"
            },
            {
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        "title": "Stat1 functions as a cytoplasmic attenuator of Runx2 in the transcriptional program of osteoblast differentiation.",
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    {
        "title": "Regulation of human Cdc25A stability by Serine 75 phosphorylation is not sufficient to activate a S phase checkpoint.",
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        "title": "P-glycoprotein but not topoisomerase II and glutathione-S-transferase-pi accounts for enhanced intracellular drug-resistance in LoVo MDR human cell lines.",
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        "title": "Signal-induced ubiquitination of I kappaB Kinase-beta.",
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                "protein_name": "Ubiquitin carboxyl-terminal hydrolase CYLD",
                "gene_name": "CYLD",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P04432-1",
                "protein_name": "Immunoglobulin kappa variable 1D-39",
                "gene_name": "IGKV1D-39",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P06315-1",
                "protein_name": "Immunoglobulin kappa variable 5-2",
                "gene_name": "IGKV5-2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01699-1",
                "protein_name": "Immunoglobulin lambda variable 1-44",
                "gene_name": "IGLV1-44",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01701-1",
                "protein_name": "Immunoglobulin lambda variable 1-51",
                "gene_name": "IGLV1-51",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01704-1",
                "protein_name": "Immunoglobulin lambda variable 2-14",
                "gene_name": "IGLV2-14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01706-1",
                "protein_name": "Immunoglobulin lambda variable 2-11",
                "gene_name": "IGLV2-11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01709-1",
                "protein_name": "Immunoglobulin lambda variable 2-8",
                "gene_name": "IGLV2-8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01717-1",
                "protein_name": "Immunoglobulin lambda variable 3-25",
                "gene_name": "IGLV3-25",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01721-1",
                "protein_name": "Immunoglobulin lambda variable 6-57",
                "gene_name": "IGLV6-57",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01703-1",
                "protein_name": "Immunoglobulin lambda variable 1-40",
                "gene_name": "IGLV1-40",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01705-1",
                "protein_name": "Immunoglobulin lambda variable 2-23",
                "gene_name": "IGLV2-23",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01715-1",
                "protein_name": "Immunoglobulin lambda variable 3-1",
                "gene_name": "IGLV3-1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01718-1",
                "protein_name": "Immunoglobulin lambda variable 3-27",
                "gene_name": "IGLV3-27",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P04211-1",
                "protein_name": "Immunoglobulin lambda variable 7-43",
                "gene_name": "IGLV7-43",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P53778-1",
                "protein_name": "Mitogen-activated protein kinase 12",
                "gene_name": "MAPK12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49721-1",
                "protein_name": "Proteasome subunit beta type-2",
                "gene_name": "PSMB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P20618-1",
                "protein_name": "Proteasome subunit beta type-1",
                "gene_name": "PSMB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43318-1",
                "protein_name": "Mitogen-activated protein kinase kinase kinase 7",
                "gene_name": "MAP3K7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49427-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 R1",
                "gene_name": "CDC34",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P20036-1",
                "protein_name": "HLA class II histocompatibility antigen, DP alpha 1 chain",
                "gene_name": "HLA-DPA1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28070-1",
                "protein_name": "Proteasome subunit beta type-4",
                "gene_name": "PSMB4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0CF74-1",
                "protein_name": "Immunoglobulin lambda constant 6",
                "gene_name": "IGLC6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01737-1",
                "protein_name": "T cell receptor alpha variable 8-4",
                "gene_name": "TRAV8-4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P04437-1",
                "protein_name": "T cell receptor alpha variable 29/delta variable 5",
                "gene_name": "TRAV29DV5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "A0A0A6YYK7-1",
                "protein_name": "T cell receptor alpha variable 19",
                "gene_name": "TRAV19",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01920-1",
                "protein_name": "HLA class II histocompatibility antigen, DQ beta 1 chain",
                "gene_name": "HLA-DQB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01906-1",
                "protein_name": "HLA class II histocompatibility antigen, DQ alpha 2 chain",
                "gene_name": "HLA-DQA2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BXN2-1",
                "protein_name": "C-type lectin domain family 7 member A",
                "gene_name": "CLEC7A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H257-1",
                "protein_name": "Caspase recruitment domain-containing protein 9",
                "gene_name": "CARD9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01911-1",
                "protein_name": "HLA class II histocompatibility antigen, DRB1 beta chain",
                "gene_name": "HLA-DRB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9HC29-1",
                "protein_name": "Nucleotide-binding oligomerization domain-containing protein 2",
                "gene_name": "NOD2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25786-1",
                "protein_name": "Proteasome subunit alpha type-1",
                "gene_name": "PSMA1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P17980-1",
                "protein_name": "26S proteasome regulatory subunit 6A",
                "gene_name": "PSMC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O00459-1",
                "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta",
                "gene_name": "PIK3R2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y297-1",
                "protein_name": "F-box/WD repeat-containing protein 1A",
                "gene_name": "BTRC",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P06239-1",
                "protein_name": "Tyrosine-protein kinase Lck",
                "gene_name": "LCK",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P07948-1",
                "protein_name": "Tyrosine-protein kinase Lyn",
                "gene_name": "LYN",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKB1-1",
                "protein_name": "F-box/WD repeat-containing protein 11",
                "gene_name": "FBXW11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P16885-1",
                "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2",
                "gene_name": "PLCG2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25788-1",
                "protein_name": "Proteasome subunit alpha type-3",
                "gene_name": "PSMA3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q14790-1",
                "protein_name": "Caspase-8",
                "gene_name": "CASP8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P04435-1",
                "protein_name": "T cell receptor beta variable 7-9",
                "gene_name": "TRBV7-9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01733-1",
                "protein_name": "T cell receptor beta variable 12-3",
                "gene_name": "TRBV12-3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N5C8-1",
                "protein_name": "TGF-beta-activated kinase 1 and MAP3K7-binding protein 3",
                "gene_name": "TAB3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P60900-1",
                "protein_name": "Proteasome subunit alpha type-6",
                "gene_name": "PSMA6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13490-1",
                "protein_name": "Baculoviral IAP repeat-containing protein 2",
                "gene_name": "BIRC2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NYJ8-1",
                "protein_name": "TGF-beta-activated kinase 1 and MAP3K7-binding protein 2",
                "gene_name": "TAB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62979-1",
                "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein",
                "gene_name": "RPS27A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P60484-1",
                "protein_name": "Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN",
                "gene_name": "PTEN",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q04759-1",
                "protein_name": "Protein kinase C theta type",
                "gene_name": "PRKCQ",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43353-1",
                "protein_name": "Receptor-interacting serine/threonine-protein kinase 2",
                "gene_name": "RIPK2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61088-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 N",
                "gene_name": "UBE2N",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62837-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 D2",
                "gene_name": "UBE2D2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13489-1",
                "protein_name": "Baculoviral IAP repeat-containing protein 3",
                "gene_name": "BIRC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01825-1",
                "protein_name": "Immunoglobulin heavy variable 4-59",
                "gene_name": "IGHV4-59",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P42338-1",
                "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform",
                "gene_name": "PIK3CB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01817-1",
                "protein_name": "Immunoglobulin heavy variable 2-5",
                "gene_name": "IGHV2-5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01824-1",
                "protein_name": "Immunoglobulin heavy variable 4-39",
                "gene_name": "IGHV4-39",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P23083-1",
                "protein_name": "Immunoglobulin heavy variable 1-2",
                "gene_name": "IGHV1-2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P48556-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 8",
                "gene_name": "PSMD8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15008-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 6",
                "gene_name": "PSMD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28072-1",
                "protein_name": "Proteasome subunit beta type-6",
                "gene_name": "PSMB6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O00232-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 12",
                "gene_name": "PSMD12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25787-1",
                "protein_name": "Proteasome subunit alpha type-2",
                "gene_name": "PSMA2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28066-1",
                "protein_name": "Proteasome subunit alpha type-5",
                "gene_name": "PSMA5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01742-1",
                "protein_name": "Immunoglobulin heavy variable 1-69",
                "gene_name": "IGHV1-69",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01768-1",
                "protein_name": "Immunoglobulin heavy variable 3-30",
                "gene_name": "IGHV3-30",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O95267-1",
                "protein_name": "RAS guanyl-releasing protein 1",
                "gene_name": "RASGRP1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01814-1",
                "protein_name": "Immunoglobulin heavy variable 2-70",
                "gene_name": "IGHV2-70",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01772-1",
                "protein_name": "Immunoglobulin heavy variable 3-33",
                "gene_name": "IGHV3-33",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01762-1",
                "protein_name": "Immunoglobulin heavy variable 3-11",
                "gene_name": "IGHV3-11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01763-1",
                "protein_name": "Immunoglobulin heavy variable 3-48",
                "gene_name": "IGHV3-48",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01764-1",
                "protein_name": "Immunoglobulin heavy variable 3-23",
                "gene_name": "IGHV3-23",
                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "P01766-1",
                "protein_name": "Immunoglobulin heavy variable 3-13",
                "gene_name": "IGHV3-13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01780-1",
                "protein_name": "Immunoglobulin heavy variable 3-7",
                "gene_name": "IGHV3-7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01782-1",
                "protein_name": "Immunoglobulin heavy variable 3-9",
                "gene_name": "IGHV3-9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P51617-1",
                "protein_name": "Interleukin-1 receptor-associated kinase 1",
                "gene_name": "IRAK1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "A0M8Q6-1",
                "protein_name": "Immunoglobulin lambda constant 7",
                "gene_name": "IGLC7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01834-1",
                "protein_name": "Immunoglobulin kappa constant",
                "gene_name": "IGKC",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0CG04-1",
                "protein_name": "Immunoglobulin lambda constant 1",
                "gene_name": "IGLC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0DOY3-1",
                "protein_name": "Immunoglobulin lambda constant 3",
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                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01848-1",
                "protein_name": "T cell receptor alpha chain constant",
                "gene_name": "TRAC",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01850-1",
                "protein_name": "T cell receptor beta constant 1",
                "gene_name": "TRBC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y239-1",
                "protein_name": "Nucleotide-binding oligomerization domain-containing protein 1",
                "gene_name": "NOD1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P07766-1",
                "protein_name": "T-cell surface glycoprotein CD3 epsilon chain",
                "gene_name": "CD3E",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01730-1",
                "protein_name": "T-cell surface glycoprotein CD4",
                "gene_name": "CD4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0CG47-1",
                "protein_name": "Polyubiquitin-B",
                "gene_name": "UBB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62987-1",
                "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein",
                "gene_name": "UBA52",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01909-1",
                "protein_name": "HLA class II histocompatibility antigen, DQ alpha 1 chain",
                "gene_name": "HLA-DQA1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P04440-1",
                "protein_name": "HLA class II histocompatibility antigen, DP beta 1 chain",
                "gene_name": "HLA-DPB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P05538-1",
                "protein_name": "HLA class II histocompatibility antigen, DQ beta 2 chain",
                "gene_name": "HLA-DQB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P13762-1",
                "protein_name": "HLA class II histocompatibility antigen, DR beta 4 chain",
                "gene_name": "HLA-DRB4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q30154-1",
                "protein_name": "HLA class II histocompatibility antigen, DR beta 5 chain",
                "gene_name": "HLA-DRB5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01903-1",
                "protein_name": "HLA class II histocompatibility antigen, DR alpha chain",
                "gene_name": "HLA-DRA",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O00487-1",
                "protein_name": "Ubiquitin C-terminal hydrolase PSMD14",
                "gene_name": "PSMD14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P79483-1",
                "protein_name": "HLA class II histocompatibility antigen, DR beta 3 chain",
                "gene_name": "HLA-DRB3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01743-1",
                "protein_name": "Immunoglobulin heavy variable 1-46",
                "gene_name": "IGHV1-46",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01854-2",
                "protein_name": "Immunoglobulin heavy constant epsilon",
                "gene_name": "IGHE",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13404-4",
                "protein_name": "Ubiquitin-conjugating enzyme E2 variant 1",
                "gene_name": "UBE2V1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "A0A0C4DH73-1",
                "protein_name": "Immunoglobulin kappa variable 1-12",
                "gene_name": "IGKV1-12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "A2NJV5-1",
                "protein_name": "Immunoglobulin kappa variable 2-29",
                "gene_name": "IGKV2-29",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01594-1",
                "protein_name": "Immunoglobulin kappa variable 1-33",
                "gene_name": "IGKV1-33",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P04430-1",
                "protein_name": "Immunoglobulin kappa variable 1-16",
                "gene_name": "IGKV1-16",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15759-1",
                "protein_name": "Mitogen-activated protein kinase 11",
                "gene_name": "MAPK11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P12319-1",
                "protein_name": "High affinity immunoglobulin epsilon receptor subunit alpha",
                "gene_name": "FCER1A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P27986-1",
                "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha",
                "gene_name": "PIK3R1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y6K9-1",
                "protein_name": "NF-kappa-B essential modulator",
                "gene_name": "IKBKG",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13685-1",
                "protein_name": "Angio-associated migratory cell protein",
                "gene_name": "AAMP",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0CG48-1",
                "protein_name": "Polyubiquitin-C",
                "gene_name": "UBC",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P63208-1",
                "protein_name": "S-phase kinase-associated protein 1",
                "gene_name": "SKP1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q04206-1",
                "protein_name": "Transcription factor p65",
                "gene_name": "RELA",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15530-1",
                "protein_name": "3-phosphoinositide-dependent protein kinase 1",
                "gene_name": "PDPK1",
                "tax_name": "Human"
            }
        ],
        "species": [
            {
                "name": "Homo sapiens",
                "taxid": 9606,
                "evidence": [
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        "title": "Tyrosine phosphorylation of plakoglobin causes contrary effects on its association with desmosomes and adherens junction components and modulates beta-catenin-mediated transcription.",
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    {
        "title": "The antiretroviral enzyme APOBEC3G is degraded by the proteasome in response to HIV-1 Vif.",
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    {
        "title": "Distinct cysteine residues in Keap1 are required for Keap1-dependent ubiquitination of Nrf2 and for stabilization of Nrf2 by chemopreventive agents and oxidative stress.",
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    {
        "title": "The negative regulator of Gli, Suppressor of fused (Sufu), interacts with SAP18, Galectin3 and other nuclear proteins.",
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            {
                "uniprot_canonical_ac": "Q96G74-1",
                "protein_name": "OTU domain-containing protein 5",
                "gene_name": "OTUD5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TE49-1",
                "protein_name": "OTU domain-containing protein 7A",
                "gene_name": "OTUD7A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5T2D3-1",
                "protein_name": "OTU domain-containing protein 3",
                "gene_name": "OTUD3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62195-1",
                "protein_name": "26S proteasome regulatory subunit 8",
                "gene_name": "PSMC5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q70CQ1-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 49",
                "gene_name": "USP49",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25789-1",
                "protein_name": "Proteasome subunit alpha type-4",
                "gene_name": "PSMA4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62191-1",
                "protein_name": "26S proteasome regulatory subunit 4",
                "gene_name": "PSMC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P40818-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 8",
                "gene_name": "USP8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49720-1",
                "protein_name": "Proteasome subunit beta type-3",
                "gene_name": "PSMB3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99460-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 1",
                "gene_name": "PSMD1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UNM6-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 13",
                "gene_name": "PSMD13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P51665-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 7",
                "gene_name": "PSMD7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13309-1",
                "protein_name": "S-phase kinase-associated protein 2",
                "gene_name": "SKP2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O95271-1",
                "protein_name": "Poly [ADP-ribose] polymerase tankyrase-1",
                "gene_name": "TNKS",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28074-1",
                "protein_name": "Proteasome subunit beta type-5",
                "gene_name": "PSMB5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P35998-1",
                "protein_name": "26S proteasome regulatory subunit 7",
                "gene_name": "PSMC2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P43686-1",
                "protein_name": "26S proteasome regulatory subunit 6B",
                "gene_name": "PSMC4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99436-1",
                "protein_name": "Proteasome subunit beta type-7",
                "gene_name": "PSMB7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q93009-1",
                "protein_name": "Ubiquitin C-terminal hydrolase 7",
                "gene_name": "USP7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y2K6-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 20",
                "gene_name": "USP20",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q14318-1",
                "protein_name": "Peptidyl-prolyl cis-trans isomerase FKBP8",
                "gene_name": "FKBP8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q14258-1",
                "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25",
                "gene_name": "TRIM25",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P51668-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 D1",
                "gene_name": "UBE2D1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13200-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 2",
                "gene_name": "PSMD2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62333-1",
                "protein_name": "26S proteasome regulatory subunit 10B",
                "gene_name": "PSMC6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P06493-1",
                "protein_name": "Cyclin-dependent kinase 1",
                "gene_name": "CDK1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P78396-1",
                "protein_name": "Cyclin-A1",
                "gene_name": "CCNA1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43303-1",
                "protein_name": "Centriolar coiled-coil protein of 110 kDa",
                "gene_name": "CCP110",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43242-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 3",
                "gene_name": "PSMD3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6GQQ9-1",
                "protein_name": "OTU domain-containing protein 7B",
                "gene_name": "OTUD7B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P14735-1",
                "protein_name": "Insulin-degrading enzyme",
                "gene_name": "IDE",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NQC7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase CYLD",
                "gene_name": "CYLD",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O95786-1",
                "protein_name": "Antiviral innate immune response receptor RIG-I",
                "gene_name": "DDX58; RIGI",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y265-1",
                "protein_name": "RuvB-like 1",
                "gene_name": "RUVBL1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UK80-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 21",
                "gene_name": "USP21",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5VVQ6-1",
                "protein_name": "Ubiquitin thioesterase OTU1",
                "gene_name": "YOD1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7TQI3-1",
                "protein_name": "Ubiquitin thioesterase OTUB1",
                "gene_name": "Otub1",
                "tax_name": "Mouse"
            },
            {
                "uniprot_canonical_ac": "Q9NZL9-1",
                "protein_name": "Methionine adenosyltransferase 2 subunit beta",
                "gene_name": "MAT2B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92830-1",
                "protein_name": "Histone acetyltransferase KAT2A",
                "gene_name": "KAT2A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49721-1",
                "protein_name": "Proteasome subunit beta type-2",
                "gene_name": "PSMB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P20618-1",
                "protein_name": "Proteasome subunit beta type-1",
                "gene_name": "PSMB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43255-1",
                "protein_name": "E3 ubiquitin-protein ligase SIAH2",
                "gene_name": "SIAH2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43318-1",
                "protein_name": "Mitogen-activated protein kinase kinase kinase 7",
                "gene_name": "MAP3K7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8IXI2-1",
                "protein_name": "Mitochondrial Rho GTPase 1",
                "gene_name": "RHOT1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P54578-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 14",
                "gene_name": "USP14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86TJ2-1",
                "protein_name": "Transcriptional adapter 2-beta",
                "gene_name": "TADA2B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96JH7-1",
                "protein_name": "Deubiquitinating protein VCPIP1",
                "gene_name": "VCPIP1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92466-1",
                "protein_name": "DNA damage-binding protein 2",
                "gene_name": "DDB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28070-1",
                "protein_name": "Proteasome subunit beta type-4",
                "gene_name": "PSMB4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UMW8-1",
                "protein_name": "Ubl carboxyl-terminal hydrolase 18",
                "gene_name": "USP18",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NFZ5-1",
                "protein_name": "TNFAIP3-interacting protein 2",
                "gene_name": "TNIP2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9JJH3-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 10",
                "gene_name": "USP17L10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9C037-1",
                "protein_name": "E3 ubiquitin-protein ligase TRIM4",
                "gene_name": "TRIM4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "A6NCW7-1",
                "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 4",
                "gene_name": "USP17L4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P45880-3",
                "protein_name": "Non-selective voltage-gated ion channel VDAC2",
                "gene_name": "VDAC2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P06746-1",
                "protein_name": "DNA polymerase beta",
                "gene_name": "POLB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P07550-1",
                "protein_name": "Beta-2 adrenergic receptor",
                "gene_name": "ADRB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7Z434-1",
                "protein_name": "Mitochondrial antiviral-signaling protein",
                "gene_name": "MAVS",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0C0S8-1",
                "protein_name": "Histone H2A type 1",
                "gene_name": "H2AC11; H2AC13; H2AC15; H2AC16; H2AC17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P36897-1",
                "protein_name": "TGF-beta receptor type-1",
                "gene_name": "TGFBR1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15105-1",
                "protein_name": "SMAD family member 7",
                "gene_name": "SMAD7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P32121-1",
                "protein_name": "Beta-arrestin-2",
                "gene_name": "ARRB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9HC29-1",
                "protein_name": "Nucleotide-binding oligomerization domain-containing protein 2",
                "gene_name": "NOD2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H2K2-1",
                "protein_name": "Poly [ADP-ribose] polymerase tankyrase-2",
                "gene_name": "TNKS2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P55072-1",
                "protein_name": "Transitional endoplasmic reticulum ATPase",
                "gene_name": "VCP",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25786-1",
                "protein_name": "Proteasome subunit alpha type-1",
                "gene_name": "PSMA1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49407-1",
                "protein_name": "Beta-arrestin-1",
                "gene_name": "ARRB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P98177-1",
                "protein_name": "Forkhead box protein O4",
                "gene_name": "FOXO4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25054-1",
                "protein_name": "Adenomatous polyposis coli protein",
                "gene_name": "APC",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15025-1",
                "protein_name": "TNFAIP3-interacting protein 1",
                "gene_name": "TNIP1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P17980-1",
                "protein_name": "26S proteasome regulatory subunit 6A",
                "gene_name": "PSMC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P03372-1",
                "protein_name": "Estrogen receptor",
                "gene_name": "ESR1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y2T1-1",
                "protein_name": "Axin-2",
                "gene_name": "AXIN2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P23771-1",
                "protein_name": "Trans-acting T-cell-specific transcription factor GATA-3",
                "gene_name": "GATA3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q16778-1",
                "protein_name": "Histone H2B type 2-E",
                "gene_name": "H2BC21",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15169-1",
                "protein_name": "Axin-1",
                "gene_name": "AXIN1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62807-1",
                "protein_name": "Histone H2B type 1-C/E/F/G/I",
                "gene_name": "H2BC10; H2BC4; H2BC6; H2BC7; H2BC8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P84022-1",
                "protein_name": "SMAD family member 3",
                "gene_name": "SMAD3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15797-1",
                "protein_name": "SMAD family member 1",
                "gene_name": "SMAD1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25788-1",
                "protein_name": "Proteasome subunit alpha type-3",
                "gene_name": "PSMA3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q80U87-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 8",
                "gene_name": "Usp8",
                "tax_name": "Mouse"
            },
            {
                "uniprot_canonical_ac": "Q8IUD6-1",
                "protein_name": "E3 ubiquitin-protein ligase RNF135",
                "gene_name": "RNF135",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q14694-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 10",
                "gene_name": "USP10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9HAU4-1",
                "protein_name": "E3 ubiquitin-protein ligase SMURF2",
                "gene_name": "SMURF2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H0E7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 44",
                "gene_name": "USP44",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86UV5-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 48",
                "gene_name": "USP48",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6RBQ6-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 17",
                "gene_name": "USP17L17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q70CQ3-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 30",
                "gene_name": "USP30",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TEY7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 33",
                "gene_name": "USP33",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6RCP7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 19",
                "gene_name": "USP17L19",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9JLJ4-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 13",
                "gene_name": "USP17L13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6RJB6-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 20",
                "gene_name": "USP17L20",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15388-1",
                "protein_name": "Mitochondrial import receptor subunit TOM20 homolog",
                "gene_name": "TOMM20",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "A6NCW0-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 3",
                "gene_name": "USP17L3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "A8MUK1-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 5",
                "gene_name": "USP17L5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9J2P7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 15",
                "gene_name": "USP17L15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9JVI0-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 11",
                "gene_name": "USP17L11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6R9N7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 18",
                "gene_name": "USP17L18",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6RA61-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 22",
                "gene_name": "USP17L22",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0C7I0-1",
                "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 8",
                "gene_name": "USP17L8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6R901-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 21",
                "gene_name": "USP17L21",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q0WX57-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 24",
                "gene_name": "USP17L24; USP17L25; USP17L26; USP17L27; USP17L28; USP17L29; USP17L30",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P60900-1",
                "protein_name": "Proteasome subunit alpha type-6",
                "gene_name": "PSMA6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13490-1",
                "protein_name": "Baculoviral IAP repeat-containing protein 2",
                "gene_name": "BIRC2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62979-1",
                "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein",
                "gene_name": "RPS27A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P60484-1",
                "protein_name": "Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN",
                "gene_name": "PTEN",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P51784-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 11",
                "gene_name": "USP11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H7L9-1",
                "protein_name": "Sin3 histone deacetylase corepressor complex component SDS3",
                "gene_name": "SUDS3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01106-2",
                "protein_name": "Myc proto-oncogene protein",
                "gene_name": "MYC",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P21796-1",
                "protein_name": "Non-selective voltage-gated ion channel VDAC1",
                "gene_name": "VDAC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43353-1",
                "protein_name": "Receptor-interacting serine/threonine-protein kinase 2",
                "gene_name": "RIPK2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y4A5-1",
                "protein_name": "Transformation/transcription domain-associated protein",
                "gene_name": "TRRAP",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96FW1-1",
                "protein_name": "Ubiquitin thioesterase OTUB1",
                "gene_name": "OTUB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P13569-1",
                "protein_name": "Cystic fibrosis transmembrane conductance regulator",
                "gene_name": "CFTR",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13489-1",
                "protein_name": "Baculoviral IAP repeat-containing protein 3",
                "gene_name": "BIRC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5QNW6-1",
                "protein_name": "Histone H2B type 2-F",
                "gene_name": "H2BC18",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P33778-1",
                "protein_name": "Histone H2B type 1-B",
                "gene_name": "H2BC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P58876-1",
                "protein_name": "Histone H2B type 1-D",
                "gene_name": "H2BC5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96A08-1",
                "protein_name": "Histone H2B type 1-A",
                "gene_name": "H2BC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P23527-1",
                "protein_name": "Histone H2B type 1-O",
                "gene_name": "H2BC17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BYX4-1",
                "protein_name": "Interferon-induced helicase C domain-containing protein 1",
                "gene_name": "IFIH1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UHP3-2",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 25",
                "gene_name": "USP25",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H9J4-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 42",
                "gene_name": "USP42",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P48556-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 8",
                "gene_name": "PSMD8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15008-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 6",
                "gene_name": "PSMD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28072-1",
                "protein_name": "Proteasome subunit beta type-6",
                "gene_name": "PSMB6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O00232-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 12",
                "gene_name": "PSMD12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25787-1",
                "protein_name": "Proteasome subunit alpha type-2",
                "gene_name": "PSMA2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28066-1",
                "protein_name": "Proteasome subunit alpha type-5",
                "gene_name": "PSMA5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5XPI4-1",
                "protein_name": "E3 ubiquitin-protein ligase RNF123",
                "gene_name": "RNF123",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q93008-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 9X",
                "gene_name": "USP9X",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O60814-1",
                "protein_name": "Histone H2B type 1-K",
                "gene_name": "H2BC12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q93077-1",
                "protein_name": "Histone H2A type 1-C",
                "gene_name": "H2AC6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q93079-1",
                "protein_name": "Histone H2B type 1-H",
                "gene_name": "H2BC9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96KK5-1",
                "protein_name": "Histone H2A type 1-H",
                "gene_name": "H2AC12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99879-1",
                "protein_name": "Histone H2B type 1-M",
                "gene_name": "H2BC14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y6I4-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 3",
                "gene_name": "USP3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96RU2-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 28",
                "gene_name": "USP28",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q70CQ2-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 34",
                "gene_name": "USP34",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O94826-1",
                "protein_name": "Mitochondrial import receptor subunit TOM70",
                "gene_name": "TOMM70",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86T82-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 37",
                "gene_name": "USP37",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BXU7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 26",
                "gene_name": "USP26",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y239-1",
                "protein_name": "Nucleotide-binding oligomerization domain-containing protein 1",
                "gene_name": "NOD1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6R6M4-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17",
                "gene_name": "USP17L2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7RTZ2-1",
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                "gene_name": "USP17L1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9HBM6-1",
                "protein_name": "Transcription initiation factor TFIID subunit 9B",
                "gene_name": "TAF9B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y277-1",
                "protein_name": "Non-selective voltage-gated ion channel VDAC3",
                "gene_name": "VDAC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O75317-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 12",
                "gene_name": "USP12",
                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "C9JPN9-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 12",
                "gene_name": "USP17L12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O75528-1",
                "protein_name": "Transcriptional adapter 3",
                "gene_name": "TADA3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q12962-1",
                "protein_name": "Transcription initiation factor TFIID subunit 10",
                "gene_name": "TAF10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y4E8-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 15",
                "gene_name": "USP15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0CG47-1",
                "protein_name": "Polyubiquitin-B",
                "gene_name": "UBB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13114-1",
                "protein_name": "TNF receptor-associated factor 3",
                "gene_name": "TRAF3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9HAW4-1",
                "protein_name": "Claspin",
                "gene_name": "CLSPN",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TBZ3-1",
                "protein_name": "WD repeat-containing protein 20",
                "gene_name": "WDR20",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P45974-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 5",
                "gene_name": "USP5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62987-1",
                "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein",
                "gene_name": "UBA52",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96KP6-1",
                "protein_name": "TNFAIP3-interacting protein 3",
                "gene_name": "TNIP3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O00487-1",
                "protein_name": "Ubiquitin C-terminal hydrolase PSMD14",
                "gene_name": "PSMD14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y256-1",
                "protein_name": "CAAX prenyl protease 2",
                "gene_name": "RCE1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NTX7-1",
                "protein_name": "E3 ubiquitin-protein ligase RNF146",
                "gene_name": "RNF146",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O95760-1",
                "protein_name": "Interleukin-33",
                "gene_name": "IL33",
                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "P04908-1",
                "protein_name": "Histone H2A type 1-B/E",
                "gene_name": "H2AC4; H2AC8",
                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "P06899-1",
                "protein_name": "Histone H2B type 1-J",
                "gene_name": "H2BC11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P20671-1",
                "protein_name": "Histone H2A type 1-D",
                "gene_name": "H2AC7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q16777-1",
                "protein_name": "Histone H2A type 2-C",
                "gene_name": "H2AC20",
                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "Q6FI13-1",
                "protein_name": "Histone H2A type 2-A",
                "gene_name": "H2AC18; H2AC19",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7L7L0-1",
                "protein_name": "Histone H2A type 3",
                "gene_name": "H2AC25",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8IUE6-1",
                "protein_name": "Histone H2A type 2-B",
                "gene_name": "H2AC21",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N257-1",
                "protein_name": "Histone H2B type 3-B",
                "gene_name": "H2BC26",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96QV6-1",
                "protein_name": "Histone H2A type 1-A",
                "gene_name": "H2AC1",
                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "Q99877-1",
                "protein_name": "Histone H2B type 1-N",
                "gene_name": "H2BC15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99878-1",
                "protein_name": "Histone H2A type 1-J",
                "gene_name": "H2AC14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99880-1",
                "protein_name": "Histone H2B type 1-L",
                "gene_name": "H2BC13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92995-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 13",
                "gene_name": "USP13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O94966-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 19",
                "gene_name": "USP19",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y5T5-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 16",
                "gene_name": "USP16",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UPU5-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 24",
                "gene_name": "USP24",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TAF3-1",
                "protein_name": "WD repeat-containing protein 48",
                "gene_name": "WDR48",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q12933-1",
                "protein_name": "TNF receptor-associated factor 2",
                "gene_name": "TRAF2",
                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "Q9Y6K9-1",
                "protein_name": "NF-kappa-B essential modulator",
                "gene_name": "IKBKG",
                "tax_name": "Human"
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            {
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            {
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            {
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            {
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            {
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            {
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            {
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            {
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            {
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                "protein_name": "Androgen receptor",
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            {
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                "protein_name": "Cellular tumor antigen p53",
                "gene_name": "TP53",
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                "common_name": "Human",
                "glygen_name": "Human",
                "reference_species": "Homo sapiens [9606]"
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        "mutagenesis": [
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                "start_pos": 748,
                "end_pos": 748,
                "sequence_org": "C",
                "sequence_mut": "A",
                "comment": "Impairs deubiquitination of EPS15, RNF128 and RNF41.",
                "evidence": [
                    {
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                        "id": "Q80U87",
                        "url": "https://www.uniprot.org/uniprotkb/Q80U87"
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                    {
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                ],
                "uniprot_canonical_ac": "Q80U87-1"
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            {
                "start_pos": 176,
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                "sequence_org": "R",
                "sequence_mut": "L",
                "comment": "No effect on RNF128.",
                "evidence": [
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                        "database": "UniProtKB",
                        "id": "Q96FW1",
                        "url": "https://www.uniprot.org/uniprotkb/Q96FW1"
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                    {
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                        "url": "https://pubmed.ncbi.nlm.nih.gov/14661020"
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                ],
                "uniprot_canonical_ac": "Q96FW1-1"
            },
            {
                "start_pos": 212,
                "end_pos": 212,
                "sequence_org": "C",
                "sequence_mut": "A",
                "comment": "No effect on RNF128.",
                "evidence": [
                    {
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                        "id": "Q96FW1",
                        "url": "https://www.uniprot.org/uniprotkb/Q96FW1"
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                    {
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                    {
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                ],
                "uniprot_canonical_ac": "Q96FW1-1"
            },
            {
                "start_pos": 91,
                "end_pos": 91,
                "sequence_org": "C",
                "sequence_mut": "A",
                "comment": "Prevents RNF128 autoubiquitination, and stabilizes RNF128 in vivo. Abolishes both ubiquitin-binding and adduct formation with ubiquitin-vinylsulfone. Does not affect ability to deubiquitinate RPTOR; when associated with A-88 and A-265.",
                "evidence": [
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                        "id": "Q96FW1",
                        "url": "https://www.uniprot.org/uniprotkb/Q96FW1"
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                    {
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                    {
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                        "url": "https://pubmed.ncbi.nlm.nih.gov/35927303"
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                "uniprot_canonical_ac": "Q96FW1-1"
            },
            {
                "start_pos": 91,
                "end_pos": 91,
                "sequence_org": "C",
                "sequence_mut": "S",
                "comment": "Abolishes hydrolase activity in vitro. Does not affect ability to inhibit RNF168. Does not affect ability to deubiquitinate DEPTOR. Abolishes ability to inhibit RNF168; when associated with E-88 and A-265.",
                "evidence": [
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                        "database": "UniProtKB",
                        "id": "Q96FW1",
                        "url": "https://www.uniprot.org/uniprotkb/Q96FW1"
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                        "id": "20725033",
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                        "url": "https://pubmed.ncbi.nlm.nih.gov/22325355"
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                        "id": "19211026",
                        "url": "https://pubmed.ncbi.nlm.nih.gov/19211026"
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                    {
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                        "id": "12704427",
                        "url": "https://pubmed.ncbi.nlm.nih.gov/12704427"
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                    {
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                        "url": "https://pubmed.ncbi.nlm.nih.gov/19383985"
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                "uniprot_canonical_ac": "Q96FW1-1"
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    {
        "title": "Structural determinants of P-glycoprotein-mediated transport of glucocorticoids.",
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        "title": "Mechanism of processing of the NF-kappa B2 p100 precursor: identification of the specific polyubiquitin chain-anchoring lysine residue and analysis of the role of NEDD8-modification on the SCF(beta-TrCP) ubiquitin ligase.",
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    {
        "title": "SCFbeta-TRCP links Chk1 signaling to degradation of the Cdc25A protein phosphatase.",
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        ]
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    {
        "title": "The structure of the APPBP1-UBA3-NEDD8-ATP complex reveals the basis for selective ubiquitin-like protein activation by an E1.",
        "journal": "Molecular cell",
        "date": "2003",
        "authors": "Walden H, Podgorski MS, Huang DT, Miller DW, Howard RJ, Minor DL Jr, Holton JM, Schulman BA",
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            },
            {
                "uniprot_canonical_ac": "Q53GT1-1",
                "protein_name": "Kelch-like protein 22",
                "gene_name": "KLHL22",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5QP82-1",
                "protein_name": "DDB1- and CUL4-associated factor 10",
                "gene_name": "DCAF10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O60662-1",
                "protein_name": "Kelch-like protein 41",
                "gene_name": "KLHL41",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9P2J3-1",
                "protein_name": "Kelch-like protein 9",
                "gene_name": "KLHL9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WWI1-1",
                "protein_name": "LIM domain only protein 7",
                "gene_name": "LMO7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NVR0-1",
                "protein_name": "Kelch-like protein 11",
                "gene_name": "KLHL11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9P2N7-1",
                "protein_name": "Kelch-like protein 13",
                "gene_name": "KLHL13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49721-1",
                "protein_name": "Proteasome subunit beta type-2",
                "gene_name": "PSMB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P20618-1",
                "protein_name": "Proteasome subunit beta type-1",
                "gene_name": "PSMB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15205-1",
                "protein_name": "Ubiquitin D",
                "gene_name": "UBD",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q16236-1",
                "protein_name": "Nuclear factor erythroid 2-related factor 2",
                "gene_name": "NFE2L2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96PQ7-1",
                "protein_name": "Kelch-like protein 5",
                "gene_name": "KLHL5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P15374-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase isozyme L3",
                "gene_name": "UCHL3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NYS7-1",
                "protein_name": "WD repeat and SOCS box-containing protein 2",
                "gene_name": "WSB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y6I7-1",
                "protein_name": "WD repeat and SOCS box-containing protein 1",
                "gene_name": "WSB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H9Q2-1",
                "protein_name": "COP9 signalosome complex subunit 7b",
                "gene_name": "COPS7B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92466-1",
                "protein_name": "DNA damage-binding protein 2",
                "gene_name": "DDB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q14999-1",
                "protein_name": "Cullin-7",
                "gene_name": "CUL7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O94888-1",
                "protein_name": "UBX domain-containing protein 7",
                "gene_name": "UBXN7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13098-4",
                "protein_name": "COP9 signalosome complex subunit 1",
                "gene_name": "GPS1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BT78-1",
                "protein_name": "COP9 signalosome complex subunit 4",
                "gene_name": "COPS4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62877-1",
                "protein_name": "E3 ubiquitin-protein ligase RBX1",
                "gene_name": "RBX1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15843-1",
                "protein_name": "Ubiquitin-like protein NEDD8",
                "gene_name": "NEDD8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61081-1",
                "protein_name": "NEDD8-conjugating enzyme Ubc12",
                "gene_name": "UBE2M",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28070-1",
                "protein_name": "Proteasome subunit beta type-4",
                "gene_name": "PSMB4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86V97-1",
                "protein_name": "Kelch repeat and BTB domain-containing protein 6",
                "gene_name": "KBTBD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WVZ9-1",
                "protein_name": "Kelch repeat and BTB domain-containing protein 7",
                "gene_name": "KBTBD7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NRJ4-1",
                "protein_name": "Tubby-related protein 4",
                "gene_name": "TULP4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61964-1",
                "protein_name": "WD repeat-containing protein 5",
                "gene_name": "WDR5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P55072-1",
                "protein_name": "Transitional endoplasmic reticulum ATPase",
                "gene_name": "VCP",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13618-1",
                "protein_name": "Cullin-3",
                "gene_name": "CUL3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25786-1",
                "protein_name": "Proteasome subunit alpha type-1",
                "gene_name": "PSMA1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NHY2-1",
                "protein_name": "E3 ubiquitin-protein ligase COP1",
                "gene_name": "COP1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7L5N1-1",
                "protein_name": "COP9 signalosome complex subunit 6",
                "gene_name": "COPS6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P40337-1",
                "protein_name": "von Hippel-Lindau disease tumor suppressor",
                "gene_name": "VHL",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5TAQ9-1",
                "protein_name": "DDB1- and CUL4-associated factor 8",
                "gene_name": "DCAF8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96BD6-1",
                "protein_name": "SPRY domain-containing SOCS box protein 1",
                "gene_name": "SPSB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5JTC6-1",
                "protein_name": "APC membrane recruitment protein 1",
                "gene_name": "AMER1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P17980-1",
                "protein_name": "26S proteasome regulatory subunit 6A",
                "gene_name": "PSMC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99619-1",
                "protein_name": "SPRY domain-containing SOCS box protein 2",
                "gene_name": "SPSB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O60826-1",
                "protein_name": "Coiled-coil domain-containing protein 22",
                "gene_name": "CCDC22",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NC69-1",
                "protein_name": "BTB/POZ domain-containing protein KCTD6",
                "gene_name": "KCTD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y297-1",
                "protein_name": "F-box/WD repeat-containing protein 1A",
                "gene_name": "BTRC",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O14544-1",
                "protein_name": "Suppressor of cytokine signaling 6",
                "gene_name": "SOCS6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKB1-1",
                "protein_name": "F-box/WD repeat-containing protein 11",
                "gene_name": "FBXW11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25788-1",
                "protein_name": "Proteasome subunit alpha type-3",
                "gene_name": "PSMA3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8IWE4-1",
                "protein_name": "DCN1-like protein 3",
                "gene_name": "DCUN1D3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UH77-1",
                "protein_name": "Kelch-like protein 3",
                "gene_name": "KLHL3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q969P5-1",
                "protein_name": "F-box only protein 32",
                "gene_name": "FBXO32",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y3I1-1",
                "protein_name": "F-box only protein 7",
                "gene_name": "FBXO7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H469-1",
                "protein_name": "F-box/LRR-repeat protein 15",
                "gene_name": "FBXL15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96CD0-1",
                "protein_name": "F-box/LRR-repeat protein 8",
                "gene_name": "FBXL8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NEE6-1",
                "protein_name": "F-box and leucine-rich repeat protein 13",
                "gene_name": "FBXL13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKT7-1",
                "protein_name": "F-box/LRR-repeat protein 3",
                "gene_name": "FBXL3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96EF6-1",
                "protein_name": "F-box only protein 17",
                "gene_name": "FBXO17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UK22-1",
                "protein_name": "F-box only protein 2",
                "gene_name": "FBXO2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P57775-1",
                "protein_name": "F-box/WD repeat-containing protein 4",
                "gene_name": "FBXW4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N1E6-1",
                "protein_name": "F-box/LRR-repeat protein 14",
                "gene_name": "FBXL14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96ME1-4",
                "protein_name": "F-box/LRR-repeat protein 18",
                "gene_name": "FBXL18",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UJT9-1",
                "protein_name": "F-box/LRR-repeat protein 7",
                "gene_name": "FBXL7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKT6-1",
                "protein_name": "Putative F-box/LRR-repeat protein 21",
                "gene_name": "FBXL21P",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O14543-1",
                "protein_name": "Suppressor of cytokine signaling 3",
                "gene_name": "SOCS3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N5D0-1",
                "protein_name": "WD and tetratricopeptide repeats protein 1",
                "gene_name": "WDTC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13501-1",
                "protein_name": "Sequestosome-1",
                "gene_name": "SQSTM1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q969U6-1",
                "protein_name": "F-box/WD repeat-containing protein 5",
                "gene_name": "FBXW5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86XK2-1",
                "protein_name": "F-box only protein 11",
                "gene_name": "FBXO11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P60900-1",
                "protein_name": "Proteasome subunit alpha type-6",
                "gene_name": "PSMA6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62979-1",
                "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein",
                "gene_name": "RPS27A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86YC2-1",
                "protein_name": "Partner and localizer of BRCA2",
                "gene_name": "PALB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H4M3-1",
                "protein_name": "F-box only protein 44",
                "gene_name": "FBXO44",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96KE9-3",
                "protein_name": "BTB/POZ domain-containing protein 6",
                "gene_name": "BTBD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92905-1",
                "protein_name": "COP9 signalosome complex subunit 5",
                "gene_name": "COPS5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13617-1",
                "protein_name": "Cullin-2",
                "gene_name": "CUL2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13619-1",
                "protein_name": "Cullin-4A",
                "gene_name": "CUL4A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86VP6-1",
                "protein_name": "Cullin-associated NEDD8-dissociated protein 1",
                "gene_name": "CAND1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62837-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 D2",
                "gene_name": "UBE2D2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13620-2",
                "protein_name": "Cullin-4B",
                "gene_name": "CUL4B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H0C5-1",
                "protein_name": "BTB/POZ domain-containing protein 1",
                "gene_name": "BTBD1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NXF7-1",
                "protein_name": "DDB1- and CUL4-associated factor 16",
                "gene_name": "DCAF16",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y2N7-1",
                "protein_name": "Hypoxia-inducible factor 3-alpha",
                "gene_name": "HIF3A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P48556-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 8",
                "gene_name": "PSMD8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15008-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 6",
                "gene_name": "PSMD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28072-1",
                "protein_name": "Proteasome subunit beta type-6",
                "gene_name": "PSMB6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O00232-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 12",
                "gene_name": "PSMD12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25787-1",
                "protein_name": "Proteasome subunit alpha type-2",
                "gene_name": "PSMA2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28066-1",
                "protein_name": "Proteasome subunit alpha type-5",
                "gene_name": "PSMA5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NCQ5-1",
                "protein_name": "F-box only protein 15",
                "gene_name": "FBXO15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UK96-1",
                "protein_name": "F-box only protein 10",
                "gene_name": "FBXO10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TB52-1",
                "protein_name": "F-box only protein 30",
                "gene_name": "FBXO30",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96JP0-1",
                "protein_name": "Protein fem-1 homolog C",
                "gene_name": "FEM1C",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UH90-1",
                "protein_name": "F-box only protein 40",
                "gene_name": "FBXO40",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q969M7-1",
                "protein_name": "NEDD8-conjugating enzyme UBE2F",
                "gene_name": "UBE2F-SCLY; UBE2F",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96LD8-1",
                "protein_name": "Sentrin-specific protease 8",
                "gene_name": "SENP8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13564-1",
                "protein_name": "NEDD8-activating enzyme E1 regulatory subunit",
                "gene_name": "NAE1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O95198-1",
                "protein_name": "Kelch-like protein 2",
                "gene_name": "KLHL2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P38936-1",
                "protein_name": "Cyclin-dependent kinase inhibitor 1",
                "gene_name": "CDKN1A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NXK8-1",
                "protein_name": "F-box/LRR-repeat protein 12",
                "gene_name": "FBXL12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0CG47-1",
                "protein_name": "Polyubiquitin-B",
                "gene_name": "UBB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKT8-1",
                "protein_name": "F-box/WD repeat-containing protein 2",
                "gene_name": "FBXW2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TEB1-1",
                "protein_name": "DDB1- and CUL4-associated factor 11",
                "gene_name": "DCAF11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TB72-1",
                "protein_name": "Pumilio homolog 2",
                "gene_name": "PUM2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BTE7-1",
                "protein_name": "DCN1-like protein 5",
                "gene_name": "DCUN1D5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q58WW2-1",
                "protein_name": "DDB1- and CUL4-associated factor 6",
                "gene_name": "DCAF6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6PH85-1",
                "protein_name": "DCN1-like protein 2",
                "gene_name": "DCUN1D2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92564-1",
                "protein_name": "DCN1-like protein 4",
                "gene_name": "DCUN1D4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96JK2-1",
                "protein_name": "DDB1- and CUL4-associated factor 5",
                "gene_name": "DCAF5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62987-1",
                "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein",
                "gene_name": "UBA52",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NZJ0-1",
                "protein_name": "Denticleless protein homolog",
                "gene_name": "DTL",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NV06-1",
                "protein_name": "DDB1- and CUL4-associated factor 13",
                "gene_name": "DCAF13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NY33-1",
                "protein_name": "Dipeptidyl peptidase 3",
                "gene_name": "DPP3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O00487-1",
                "protein_name": "Ubiquitin C-terminal hydrolase PSMD14",
                "gene_name": "PSMD14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O94952-2",
                "protein_name": "F-box only protein 21",
                "gene_name": "FBXO21",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TF61-1",
                "protein_name": "F-box only protein 41",
                "gene_name": "FBXO41",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BSK4-1",
                "protein_name": "Protein fem-1 homolog A",
                "gene_name": "FEM1A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96IG2-1",
                "protein_name": "F-box/LRR-repeat protein 20",
                "gene_name": "FBXL20",
                "tax_name": "Human"
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                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O14933-1",
                "protein_name": "Ubiquitin/ISG15-conjugating enzyme E2 L6",
                "gene_name": "UBE2L6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13191-1",
                "protein_name": "E3 ubiquitin-protein ligase CBL-B",
                "gene_name": "CBLB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6ZVZ8-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 18",
                "gene_name": "ASB18",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N6D2-1",
                "protein_name": "E3 ubiquitin-protein ligase RNF182",
                "gene_name": "RNF182",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NV58-1",
                "protein_name": "E3 ubiquitin-protein ligase RNF19A",
                "gene_name": "RNF19A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TC41-1",
                "protein_name": "E3 ubiquitin-protein ligase RNF217",
                "gene_name": "RNF217",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P41002-1",
                "protein_name": "Cyclin-F",
                "gene_name": "CCNF",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61086-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 K",
                "gene_name": "UBE2K",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15524-1",
                "protein_name": "Suppressor of cytokine signaling 1",
                "gene_name": "SOCS1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q05516-1",
                "protein_name": "Zinc finger and BTB domain-containing protein 16",
                "gene_name": "ZBTB16",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15369-1",
                "protein_name": "Elongin-C",
                "gene_name": "ELOC",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P46934-1",
                "protein_name": "E3 ubiquitin-protein ligase NEDD4",
                "gene_name": "NEDD4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TBC4-1",
                "protein_name": "NEDD8-activating enzyme E1 catalytic subunit",
                "gene_name": "UBA3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7L5Y6-1",
                "protein_name": "DET1 homolog",
                "gene_name": "DET1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62195-1",
                "protein_name": "26S proteasome regulatory subunit 8",
                "gene_name": "PSMC5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NI29-1",
                "protein_name": "F-box only protein 27",
                "gene_name": "FBXO27",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6P050-1",
                "protein_name": "F-box and leucine-rich protein 22",
                "gene_name": "FBXL22",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NEZ5-1",
                "protein_name": "F-box only protein 22",
                "gene_name": "FBXO22",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P22314-1",
                "protein_name": "Ubiquitin-like modifier-activating enzyme 1",
                "gene_name": "UBA1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NRD1-1",
                "protein_name": "F-box only protein 6",
                "gene_name": "FBXO6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5XUX1-3",
                "protein_name": "F-box/WD repeat-containing protein 9",
                "gene_name": "FBXW9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N3Y1-1",
                "protein_name": "F-box/WD repeat-containing protein 8",
                "gene_name": "FBXW8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UK97-1",
                "protein_name": "F-box only protein 9",
                "gene_name": "FBXO9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKA1-1",
                "protein_name": "F-box/LRR-repeat protein 5",
                "gene_name": "FBXL5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKA2-1",
                "protein_name": "F-box/LRR-repeat protein 4",
                "gene_name": "FBXL4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6PCT2-1",
                "protein_name": "F-box/LRR-repeat protein 19",
                "gene_name": "FBXL19",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N461-1",
                "protein_name": "F-box/LRR-repeat protein 16",
                "gene_name": "FBXL16",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92990-1",
                "protein_name": "Glomulin",
                "gene_name": "GLMN",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WVD3-1",
                "protein_name": "E3 ubiquitin-protein ligase RNF138",
                "gene_name": "RNF138",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25789-1",
                "protein_name": "Proteasome subunit alpha type-4",
                "gene_name": "PSMA4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H2C0-1",
                "protein_name": "Gigaxonin",
                "gene_name": "GAN",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86XS8-1",
                "protein_name": "E3 ubiquitin-protein ligase RNF130",
                "gene_name": "RNF130",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15386-1",
                "protein_name": "Ubiquitin-protein ligase E3C",
                "gene_name": "UBE3C",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5VVX9-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 U",
                "gene_name": "UBE2U",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15345-2",
                "protein_name": "Leucine-rich repeat-containing protein 41",
                "gene_name": "LRRC41",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96MP8-1",
                "protein_name": "BTB/POZ domain-containing protein KCTD7",
                "gene_name": "KCTD7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9JR72-1",
                "protein_name": "Kelch repeat and BTB domain-containing protein 13",
                "gene_name": "KBTBD13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O94822-1",
                "protein_name": "E3 ubiquitin-protein ligase listerin",
                "gene_name": "LTN1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H0H3-1",
                "protein_name": "Kelch-like protein 25",
                "gene_name": "KLHL25",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UJP4-1",
                "protein_name": "Kelch-like protein 21",
                "gene_name": "KLHL21",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q2Q1W2-1",
                "protein_name": "E3 ubiquitin-protein ligase TRIM71",
                "gene_name": "TRIM71",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96L50-1",
                "protein_name": "Leucine-rich repeat protein 1",
                "gene_name": "LRR1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O60291-1",
                "protein_name": "E3 ubiquitin-protein ligase MGRN1",
                "gene_name": "MGRN1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62191-1",
                "protein_name": "26S proteasome regulatory subunit 4",
                "gene_name": "PSMC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BYM8-1",
                "protein_name": "RanBP-type and C3HC4-type zinc finger-containing protein 1",
                "gene_name": "RBCK1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H832-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 Z",
                "gene_name": "UBE2Z",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "A0AVT1-1",
                "protein_name": "Ubiquitin-like modifier-activating enzyme 6",
                "gene_name": "UBA6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49720-1",
                "protein_name": "Proteasome subunit beta type-3",
                "gene_name": "PSMB3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99460-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 1",
                "gene_name": "PSMD1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UNM6-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 13",
                "gene_name": "PSMD13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q969T4-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 E3",
                "gene_name": "UBE2E3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P51665-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 7",
                "gene_name": "PSMD7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13309-1",
                "protein_name": "S-phase kinase-associated protein 2",
                "gene_name": "SKP2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7Z7E8-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 Q1",
                "gene_name": "UBE2Q1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5U5Q3-1",
                "protein_name": "RNA-binding E3 ubiquitin-protein ligase MEX3C",
                "gene_name": "MEX3C",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96F44-1",
                "protein_name": "E3 ubiquitin-protein ligase TRIM11",
                "gene_name": "TRIM11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96AX9-1",
                "protein_name": "E3 ubiquitin-protein ligase MIB2",
                "gene_name": "MIB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28074-1",
                "protein_name": "Proteasome subunit beta type-5",
                "gene_name": "PSMB5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P35998-1",
                "protein_name": "26S proteasome regulatory subunit 7",
                "gene_name": "PSMC2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P43686-1",
                "protein_name": "26S proteasome regulatory subunit 6B",
                "gene_name": "PSMC4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99436-1",
                "protein_name": "Proteasome subunit beta type-7",
                "gene_name": "PSMB7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NVW2-1",
                "protein_name": "E3 ubiquitin-protein ligase RLIM",
                "gene_name": "RLIM",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q63HN8-3",
                "protein_name": "E3 ubiquitin-protein ligase RNF213",
                "gene_name": "RNF213",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5VTB9-1",
                "protein_name": "E3 ubiquitin-protein ligase RNF220",
                "gene_name": "RNF220",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6ZMZ0-1",
                "protein_name": "E3 ubiquitin-protein ligase RNF19B",
                "gene_name": "RNF19B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5XUX0-1",
                "protein_name": "F-box only protein 31",
                "gene_name": "FBXO31",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9C0C9-1",
                "protein_name": "(E3-independent) E2 ubiquitin-conjugating enzyme",
                "gene_name": "UBE2O",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15370-1",
                "protein_name": "Elongin-B",
                "gene_name": "ELOB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61077-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 D3",
                "gene_name": "UBE2D3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P51668-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 D1",
                "gene_name": "UBE2D1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXI3-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 10",
                "gene_name": "ASB10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13200-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 2",
                "gene_name": "PSMD2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXK1-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 15",
                "gene_name": "ASB15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H765-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 8",
                "gene_name": "ASB8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y576-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 1",
                "gene_name": "ASB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96NS5-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 16",
                "gene_name": "ASB16",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXH4-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 11",
                "gene_name": "ASB11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXJ9-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 17",
                "gene_name": "ASB17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXK3-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 13",
                "gene_name": "ASB13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXK4-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 12",
                "gene_name": "ASB12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NWX5-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 6",
                "gene_name": "ASB6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y575-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 3",
                "gene_name": "ASB3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96LR5-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 E2",
                "gene_name": "UBE2E2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O95352-1",
                "protein_name": "Ubiquitin-like modifier-activating enzyme ATG7",
                "gene_name": "ATG7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7Z419-1",
                "protein_name": "E3 ubiquitin-protein ligase RNF144B",
                "gene_name": "RNF144B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BV68-1",
                "protein_name": "E3 ubiquitin-protein ligase RNF126",
                "gene_name": "RNF126",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96J02-1",
                "protein_name": "E3 ubiquitin-protein ligase Itchy homolog",
                "gene_name": "ITCH",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62333-1",
                "protein_name": "26S proteasome regulatory subunit 10B",
                "gene_name": "PSMC6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WWX0-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 5",
                "gene_name": "ASB5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96DX5-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 9",
                "gene_name": "ASB9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43242-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 3",
                "gene_name": "PSMD3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q969H0-1",
                "protein_name": "F-box/WD repeat-containing protein 7",
                "gene_name": "FBXW7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q969Q1-1",
                "protein_name": "E3 ubiquitin-protein ligase TRIM63",
                "gene_name": "TRIM63",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WY64-1",
                "protein_name": "E3 ubiquitin-protein ligase MYLIP",
                "gene_name": "MYLIP",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q53GT1-1",
                "protein_name": "Kelch-like protein 22",
                "gene_name": "KLHL22",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y4B6-1",
                "protein_name": "DDB1- and CUL4-associated factor 1",
                "gene_name": "DCAF1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O60662-1",
                "protein_name": "Kelch-like protein 41",
                "gene_name": "KLHL41",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6Q0C0-1",
                "protein_name": "E3 ubiquitin-protein ligase TRAF7",
                "gene_name": "TRAF7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9P2J3-1",
                "protein_name": "Kelch-like protein 9",
                "gene_name": "KLHL9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6UWE0-1",
                "protein_name": "E3 ubiquitin-protein ligase LRSAM1",
                "gene_name": "LRSAM1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WWI1-1",
                "protein_name": "LIM domain only protein 7",
                "gene_name": "LMO7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NQ86-1",
                "protein_name": "E3 ubiquitin-protein ligase TRIM36",
                "gene_name": "TRIM36",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NVR0-1",
                "protein_name": "Kelch-like protein 11",
                "gene_name": "KLHL11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9P2N7-1",
                "protein_name": "Kelch-like protein 13",
                "gene_name": "KLHL13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49721-1",
                "protein_name": "Proteasome subunit beta type-2",
                "gene_name": "PSMB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P20618-1",
                "protein_name": "Proteasome subunit beta type-1",
                "gene_name": "PSMB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43255-1",
                "protein_name": "E3 ubiquitin-protein ligase SIAH2",
                "gene_name": "SIAH2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96PQ7-1",
                "protein_name": "Kelch-like protein 5",
                "gene_name": "KLHL5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96BH1-1",
                "protein_name": "E3 ubiquitin-protein ligase RNF25",
                "gene_name": "RNF25",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y6I7-1",
                "protein_name": "WD repeat and SOCS box-containing protein 1",
                "gene_name": "WSB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q14999-1",
                "protein_name": "Cullin-7",
                "gene_name": "CUL7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49427-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 R1",
                "gene_name": "CDC34",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62877-1",
                "protein_name": "E3 ubiquitin-protein ligase RBX1",
                "gene_name": "RBX1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61081-1",
                "protein_name": "NEDD8-conjugating enzyme Ubc12",
                "gene_name": "UBE2M",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28070-1",
                "protein_name": "Proteasome subunit beta type-4",
                "gene_name": "PSMB4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9GZZ9-1",
                "protein_name": "Ubiquitin-like modifier-activating enzyme 5",
                "gene_name": "UBA5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86V97-1",
                "protein_name": "Kelch repeat and BTB domain-containing protein 6",
                "gene_name": "KBTBD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WVZ9-1",
                "protein_name": "Kelch repeat and BTB domain-containing protein 7",
                "gene_name": "KBTBD7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62256-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 H",
                "gene_name": "UBE2H",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P41226-1",
                "protein_name": "Ubiquitin-like modifier-activating enzyme 7",
                "gene_name": "UBA7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q14139-1",
                "protein_name": "Ubiquitin conjugation factor E4 A",
                "gene_name": "UBE4A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96B02-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 W",
                "gene_name": "UBE2W",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9C037-1",
                "protein_name": "E3 ubiquitin-protein ligase TRIM4",
                "gene_name": "TRIM4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P29144-1",
                "protein_name": "Tripeptidyl-peptidase 2",
                "gene_name": "TPP2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13618-1",
                "protein_name": "Cullin-3",
                "gene_name": "CUL3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25786-1",
                "protein_name": "Proteasome subunit alpha type-1",
                "gene_name": "PSMA1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q17RB8-1",
                "protein_name": "LON peptidase N-terminal domain and RING finger protein 1",
                "gene_name": "LONRF1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q16763-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 S",
                "gene_name": "UBE2S",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P40337-1",
                "protein_name": "von Hippel-Lindau disease tumor suppressor",
                "gene_name": "VHL",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86Y13-1",
                "protein_name": "E3 ubiquitin-protein ligase DZIP3",
                "gene_name": "DZIP3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96BD6-1",
                "protein_name": "SPRY domain-containing SOCS box protein 1",
                "gene_name": "SPSB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BS18-1",
                "protein_name": "Anaphase-promoting complex subunit 13",
                "gene_name": "ANAPC13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P17980-1",
                "protein_name": "26S proteasome regulatory subunit 6A",
                "gene_name": "PSMC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99619-1",
                "protein_name": "SPRY domain-containing SOCS box protein 2",
                "gene_name": "SPSB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UM13-1",
                "protein_name": "Anaphase-promoting complex subunit 10",
                "gene_name": "ANAPC10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TBB1-1",
                "protein_name": "E3 ubiquitin-protein ligase LNX",
                "gene_name": "LNX1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WV44-1",
                "protein_name": "E3 ubiquitin-protein ligase TRIM41",
                "gene_name": "TRIM41",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UJX6-1",
                "protein_name": "Anaphase-promoting complex subunit 2",
                "gene_name": "ANAPC2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NC69-1",
                "protein_name": "BTB/POZ domain-containing protein KCTD6",
                "gene_name": "KCTD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UJX2-1",
                "protein_name": "Cell division cycle protein 23 homolog",
                "gene_name": "CDC23",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96PM5-1",
                "protein_name": "RING finger and CHY zinc finger domain-containing protein 1",
                "gene_name": "RCHY1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NYG5-1",
                "protein_name": "Anaphase-promoting complex subunit 11",
                "gene_name": "ANAPC11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y297-1",
                "protein_name": "F-box/WD repeat-containing protein 1A",
                "gene_name": "BTRC",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O60260-1",
                "protein_name": "E3 ubiquitin-protein ligase parkin",
                "gene_name": "PRKN",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKB1-1",
                "protein_name": "F-box/WD repeat-containing protein 11",
                "gene_name": "FBXW11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9C026-1",
                "protein_name": "E3 ubiquitin-protein ligase TRIM9",
                "gene_name": "TRIM9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UBS8-1",
                "protein_name": "E3 ubiquitin-protein ligase RNF14",
                "gene_name": "RNF14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P30260-1",
                "protein_name": "Cell division cycle protein 27 homolog",
                "gene_name": "CDC27",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25788-1",
                "protein_name": "Proteasome subunit alpha type-3",
                "gene_name": "PSMA3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H0M0-1",
                "protein_name": "NEDD4-like E3 ubiquitin-protein ligase WWP1",
                "gene_name": "WWP1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UH77-1",
                "protein_name": "Kelch-like protein 3",
                "gene_name": "KLHL3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q969P5-1",
                "protein_name": "F-box only protein 32",
                "gene_name": "FBXO32",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y3I1-1",
                "protein_name": "F-box only protein 7",
                "gene_name": "FBXO7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9HCE7-1",
                "protein_name": "E3 ubiquitin-protein ligase SMURF1",
                "gene_name": "SMURF1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H469-1",
                "protein_name": "F-box/LRR-repeat protein 15",
                "gene_name": "FBXL15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96CD0-1",
                "protein_name": "F-box/LRR-repeat protein 8",
                "gene_name": "FBXL8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NEE6-1",
                "protein_name": "F-box and leucine-rich repeat protein 13",
                "gene_name": "FBXL13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKT7-1",
                "protein_name": "F-box/LRR-repeat protein 3",
                "gene_name": "FBXL3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96EF6-1",
                "protein_name": "F-box only protein 17",
                "gene_name": "FBXO17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UK22-1",
                "protein_name": "F-box only protein 2",
                "gene_name": "FBXO2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P57775-1",
                "protein_name": "F-box/WD repeat-containing protein 4",
                "gene_name": "FBXW4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N1E6-1",
                "protein_name": "F-box/LRR-repeat protein 14",
                "gene_name": "FBXL14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96ME1-4",
                "protein_name": "F-box/LRR-repeat protein 18",
                "gene_name": "FBXL18",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UJT9-1",
                "protein_name": "F-box/LRR-repeat protein 7",
                "gene_name": "FBXL7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKT6-1",
                "protein_name": "Putative F-box/LRR-repeat protein 21",
                "gene_name": "FBXL21P",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9HAU4-1",
                "protein_name": "E3 ubiquitin-protein ligase SMURF2",
                "gene_name": "SMURF2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O14543-1",
                "protein_name": "Suppressor of cytokine signaling 3",
                "gene_name": "SOCS3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N2K1-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 J2",
                "gene_name": "UBE2J2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O00762-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 C",
                "gene_name": "UBE2C",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WVN8-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 Q2",
                "gene_name": "UBE2Q2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q969U6-1",
                "protein_name": "F-box/WD repeat-containing protein 5",
                "gene_name": "FBXW5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86XK2-1",
                "protein_name": "F-box only protein 11",
                "gene_name": "FBXO11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P60900-1",
                "protein_name": "Proteasome subunit alpha type-6",
                "gene_name": "PSMA6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62979-1",
                "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein",
                "gene_name": "RPS27A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H4M3-1",
                "protein_name": "F-box only protein 44",
                "gene_name": "FBXO44",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96KE9-3",
                "protein_name": "BTB/POZ domain-containing protein 6",
                "gene_name": "BTBD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61088-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 N",
                "gene_name": "UBE2N",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13617-1",
                "protein_name": "Cullin-2",
                "gene_name": "CUL2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6ZNA4-1",
                "protein_name": "E3 ubiquitin-protein ligase Arkadia",
                "gene_name": "RNF111",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P51965-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 E1",
                "gene_name": "UBE2E1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62837-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 D2",
                "gene_name": "UBE2D2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H0C5-1",
                "protein_name": "BTB/POZ domain-containing protein 1",
                "gene_name": "BTBD1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UII4-1",
                "protein_name": "E3 ISG15--protein ligase HERC5",
                "gene_name": "HERC5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15751-1",
                "protein_name": "Probable E3 ubiquitin-protein ligase HERC1",
                "gene_name": "HERC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5T447-1",
                "protein_name": "E3 ubiquitin-protein ligase HECTD3",
                "gene_name": "HECTD3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q05086-1",
                "protein_name": "Ubiquitin-protein ligase E3A",
                "gene_name": "UBE3A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43164-1",
                "protein_name": "E3 ubiquitin-protein ligase Praja-2",
                "gene_name": "PJA2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86XT4-1",
                "protein_name": "E3 ubiquitin-protein ligase TRIM50",
                "gene_name": "TRIM50",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P55786-1",
                "protein_name": "Puromycin-sensitive aminopeptidase",
                "gene_name": "NPEPPS",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P78317-1",
                "protein_name": "E3 ubiquitin-protein ligase RNF4",
                "gene_name": "RNF4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49459-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 A",
                "gene_name": "UBE2A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P48556-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 8",
                "gene_name": "PSMD8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15008-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 6",
                "gene_name": "PSMD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28072-1",
                "protein_name": "Proteasome subunit beta type-6",
                "gene_name": "PSMB6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O00232-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 12",
                "gene_name": "PSMD12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7Z6E9-1",
                "protein_name": "E3 ubiquitin-protein ligase RBBP6",
                "gene_name": "RBBP6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25787-1",
                "protein_name": "Proteasome subunit alpha type-2",
                "gene_name": "PSMA2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28066-1",
                "protein_name": "Proteasome subunit alpha type-5",
                "gene_name": "PSMA5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5XPI4-1",
                "protein_name": "E3 ubiquitin-protein ligase RNF123",
                "gene_name": "RNF123",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9ULT8-1",
                "protein_name": "E3 ubiquitin-protein ligase HECTD1",
                "gene_name": "HECTD1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NCQ5-1",
                "protein_name": "F-box only protein 15",
                "gene_name": "FBXO15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5GLZ8-1",
                "protein_name": "Probable E3 ubiquitin-protein ligase HERC4",
                "gene_name": "HERC4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8IVU3-1",
                "protein_name": "Probable E3 ubiquitin-protein ligase HERC6",
                "gene_name": "HERC6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UK96-1",
                "protein_name": "F-box only protein 10",
                "gene_name": "FBXO10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P63146-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 B",
                "gene_name": "UBE2B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5U5R9-1",
                "protein_name": "Probable E3 ubiquitin-protein ligase HECTD2",
                "gene_name": "HECTD2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TB52-1",
                "protein_name": "F-box only protein 30",
                "gene_name": "FBXO30",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UH90-1",
                "protein_name": "F-box only protein 40",
                "gene_name": "FBXO40",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7Z6J0-1",
                "protein_name": "E3 ubiquitin-protein ligase SH3RF1",
                "gene_name": "SH3RF1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H9P5-4",
                "protein_name": "Putative E3 ubiquitin-protein ligase UNKL",
                "gene_name": "UNKL",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8IWV7-1",
                "protein_name": "E3 ubiquitin-protein ligase UBR1",
                "gene_name": "UBR1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q969M7-1",
                "protein_name": "NEDD8-conjugating enzyme UBE2F",
                "gene_name": "UBE2F-SCLY; UBE2F",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15819-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 variant 2",
                "gene_name": "UBE2V2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62253-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 G1",
                "gene_name": "UBE2G1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7Z6J8-1",
                "protein_name": "E3 ubiquitin-protein ligase E3D",
                "gene_name": "UBE3D",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8ND25-1",
                "protein_name": "E3 ubiquitin-protein ligase ZNRF1",
                "gene_name": "ZNRF1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8IWV8-1",
                "protein_name": "E3 ubiquitin-protein ligase UBR2",
                "gene_name": "UBR2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5T4S7-1",
                "protein_name": "E3 ubiquitin-protein ligase UBR4",
                "gene_name": "UBR4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y385-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 J1",
                "gene_name": "UBE2J1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N7E2-1",
                "protein_name": "E3 ubiquitin-protein ligase CBLL2",
                "gene_name": "CBLL2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NHG8-1",
                "protein_name": "E3 ubiquitin-protein ligase ZNRF2",
                "gene_name": "ZNRF2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O95198-1",
                "protein_name": "Kelch-like protein 2",
                "gene_name": "KLHL2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13042-1",
                "protein_name": "Cell division cycle protein 16 homolog",
                "gene_name": "CDC16",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9HCM9-1",
                "protein_name": "E3 ubiquitin-protein ligase TRIM39",
                "gene_name": "TRIM39",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UM11-1",
                "protein_name": "Fizzy-related protein homolog",
                "gene_name": "FZR1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NXK8-1",
                "protein_name": "F-box/LRR-repeat protein 12",
                "gene_name": "FBXL12",
                "tax_name": "Human"
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                "uniprot_canonical_ac": "P62191-1",
                "protein_name": "26S proteasome regulatory subunit 4",
                "gene_name": "PSMC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UBW8-1",
                "protein_name": "COP9 signalosome complex subunit 7a",
                "gene_name": "COPS7A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99627-1",
                "protein_name": "COP9 signalosome complex subunit 8",
                "gene_name": "COPS8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O75147-3",
                "protein_name": "Obscurin-like protein 1",
                "gene_name": "OBSL1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49720-1",
                "protein_name": "Proteasome subunit beta type-3",
                "gene_name": "PSMB3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99460-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 1",
                "gene_name": "PSMD1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UNM6-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 13",
                "gene_name": "PSMD13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P51665-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 7",
                "gene_name": "PSMD7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NSE2-1",
                "protein_name": "Cytokine-inducible SH2-containing protein",
                "gene_name": "CISH",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13309-1",
                "protein_name": "S-phase kinase-associated protein 2",
                "gene_name": "SKP2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BR09-1",
                "protein_name": "Neuralized-like protein 2",
                "gene_name": "NEURL2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28074-1",
                "protein_name": "Proteasome subunit beta type-5",
                "gene_name": "PSMB5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P35998-1",
                "protein_name": "26S proteasome regulatory subunit 7",
                "gene_name": "PSMC2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P43686-1",
                "protein_name": "26S proteasome regulatory subunit 6B",
                "gene_name": "PSMC4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99436-1",
                "protein_name": "Proteasome subunit beta type-7",
                "gene_name": "PSMB7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15392-1",
                "protein_name": "Baculoviral IAP repeat-containing protein 5",
                "gene_name": "BIRC5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5XUX0-1",
                "protein_name": "F-box only protein 31",
                "gene_name": "FBXO31",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15370-1",
                "protein_name": "Elongin-B",
                "gene_name": "ELOB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61077-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 D3",
                "gene_name": "UBE2D3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P51668-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 D1",
                "gene_name": "UBE2D1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O14508-1",
                "protein_name": "Suppressor of cytokine signaling 2",
                "gene_name": "SOCS2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q16531-1",
                "protein_name": "DNA damage-binding protein 1",
                "gene_name": "DDB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXI3-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 10",
                "gene_name": "ASB10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13200-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 2",
                "gene_name": "PSMD2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96GG9-1",
                "protein_name": "DCN1-like protein 1",
                "gene_name": "DCUN1D1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXK1-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 15",
                "gene_name": "ASB15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H765-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 8",
                "gene_name": "ASB8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y576-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 1",
                "gene_name": "ASB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96NS5-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 16",
                "gene_name": "ASB16",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXH4-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 11",
                "gene_name": "ASB11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXJ9-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 17",
                "gene_name": "ASB17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXK3-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 13",
                "gene_name": "ASB13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXK4-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 12",
                "gene_name": "ASB12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NWX5-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 6",
                "gene_name": "ASB6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y575-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 3",
                "gene_name": "ASB3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99814-1",
                "protein_name": "Endothelial PAS domain-containing protein 1",
                "gene_name": "EPAS1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BW61-1",
                "protein_name": "DET1- and DDB1-associated protein 1",
                "gene_name": "DDA1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N668-1",
                "protein_name": "COMM domain-containing protein 1",
                "gene_name": "COMMD1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62333-1",
                "protein_name": "26S proteasome regulatory subunit 10B",
                "gene_name": "PSMC6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WWX0-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 5",
                "gene_name": "ASB5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96DX5-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 9",
                "gene_name": "ASB9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UBI1-1",
                "protein_name": "COMM domain-containing protein 3",
                "gene_name": "COMMD3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61201-1",
                "protein_name": "COP9 signalosome complex subunit 2",
                "gene_name": "COPS2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7Z4G1-1",
                "protein_name": "COMM domain-containing protein 6",
                "gene_name": "COMMD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H0A8-1",
                "protein_name": "COMM domain-containing protein 4",
                "gene_name": "COMMD4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y6G5-1",
                "protein_name": "COMM domain-containing protein 10",
                "gene_name": "COMMD10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43242-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 3",
                "gene_name": "PSMD3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H0W5-1",
                "protein_name": "Coiled-coil domain-containing protein 8",
                "gene_name": "CCDC8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86X83-1",
                "protein_name": "COMM domain-containing protein 2",
                "gene_name": "COMMD2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86VX2-1",
                "protein_name": "COMM domain-containing protein 7",
                "gene_name": "COMMD7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9P000-1",
                "protein_name": "COMM domain-containing protein 9",
                "gene_name": "COMMD9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q969H0-1",
                "protein_name": "F-box/WD repeat-containing protein 7",
                "gene_name": "FBXW7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NX08-1",
                "protein_name": "COMM domain-containing protein 8",
                "gene_name": "COMMD8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9GZQ3-1",
                "protein_name": "COMM domain-containing protein 5",
                "gene_name": "COMMD5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5H9S7-1",
                "protein_name": "DDB1- and CUL4-associated factor 17",
                "gene_name": "DCAF17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61962-1",
                "protein_name": "DDB1- and CUL4-associated factor 7",
                "gene_name": "DCAF7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WV16-1",
                "protein_name": "DDB1- and CUL4-associated factor 4",
                "gene_name": "DCAF4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q53GT1-1",
                "protein_name": "Kelch-like protein 22",
                "gene_name": "KLHL22",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5QP82-1",
                "protein_name": "DDB1- and CUL4-associated factor 10",
                "gene_name": "DCAF10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O60662-1",
                "protein_name": "Kelch-like protein 41",
                "gene_name": "KLHL41",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9P2J3-1",
                "protein_name": "Kelch-like protein 9",
                "gene_name": "KLHL9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WWI1-1",
                "protein_name": "LIM domain only protein 7",
                "gene_name": "LMO7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NVR0-1",
                "protein_name": "Kelch-like protein 11",
                "gene_name": "KLHL11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9P2N7-1",
                "protein_name": "Kelch-like protein 13",
                "gene_name": "KLHL13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49721-1",
                "protein_name": "Proteasome subunit beta type-2",
                "gene_name": "PSMB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P20618-1",
                "protein_name": "Proteasome subunit beta type-1",
                "gene_name": "PSMB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15205-1",
                "protein_name": "Ubiquitin D",
                "gene_name": "UBD",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q16236-1",
                "protein_name": "Nuclear factor erythroid 2-related factor 2",
                "gene_name": "NFE2L2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96PQ7-1",
                "protein_name": "Kelch-like protein 5",
                "gene_name": "KLHL5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P15374-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase isozyme L3",
                "gene_name": "UCHL3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NYS7-1",
                "protein_name": "WD repeat and SOCS box-containing protein 2",
                "gene_name": "WSB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y6I7-1",
                "protein_name": "WD repeat and SOCS box-containing protein 1",
                "gene_name": "WSB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H9Q2-1",
                "protein_name": "COP9 signalosome complex subunit 7b",
                "gene_name": "COPS7B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92466-1",
                "protein_name": "DNA damage-binding protein 2",
                "gene_name": "DDB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q14999-1",
                "protein_name": "Cullin-7",
                "gene_name": "CUL7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O94888-1",
                "protein_name": "UBX domain-containing protein 7",
                "gene_name": "UBXN7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13098-4",
                "protein_name": "COP9 signalosome complex subunit 1",
                "gene_name": "GPS1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BT78-1",
                "protein_name": "COP9 signalosome complex subunit 4",
                "gene_name": "COPS4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62877-1",
                "protein_name": "E3 ubiquitin-protein ligase RBX1",
                "gene_name": "RBX1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15843-1",
                "protein_name": "Ubiquitin-like protein NEDD8",
                "gene_name": "NEDD8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61081-1",
                "protein_name": "NEDD8-conjugating enzyme Ubc12",
                "gene_name": "UBE2M",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28070-1",
                "protein_name": "Proteasome subunit beta type-4",
                "gene_name": "PSMB4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86V97-1",
                "protein_name": "Kelch repeat and BTB domain-containing protein 6",
                "gene_name": "KBTBD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WVZ9-1",
                "protein_name": "Kelch repeat and BTB domain-containing protein 7",
                "gene_name": "KBTBD7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NRJ4-1",
                "protein_name": "Tubby-related protein 4",
                "gene_name": "TULP4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y5A7-1",
                "protein_name": "NEDD8 ultimate buster 1",
                "gene_name": "NUB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61964-1",
                "protein_name": "WD repeat-containing protein 5",
                "gene_name": "WDR5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P55072-1",
                "protein_name": "Transitional endoplasmic reticulum ATPase",
                "gene_name": "VCP",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13618-1",
                "protein_name": "Cullin-3",
                "gene_name": "CUL3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25786-1",
                "protein_name": "Proteasome subunit alpha type-1",
                "gene_name": "PSMA1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NHY2-1",
                "protein_name": "E3 ubiquitin-protein ligase COP1",
                "gene_name": "COP1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7L5N1-1",
                "protein_name": "COP9 signalosome complex subunit 6",
                "gene_name": "COPS6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P40337-1",
                "protein_name": "von Hippel-Lindau disease tumor suppressor",
                "gene_name": "VHL",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5TAQ9-1",
                "protein_name": "DDB1- and CUL4-associated factor 8",
                "gene_name": "DCAF8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96BD6-1",
                "protein_name": "SPRY domain-containing SOCS box protein 1",
                "gene_name": "SPSB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5JTC6-1",
                "protein_name": "APC membrane recruitment protein 1",
                "gene_name": "AMER1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P17980-1",
                "protein_name": "26S proteasome regulatory subunit 6A",
                "gene_name": "PSMC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99619-1",
                "protein_name": "SPRY domain-containing SOCS box protein 2",
                "gene_name": "SPSB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O60826-1",
                "protein_name": "Coiled-coil domain-containing protein 22",
                "gene_name": "CCDC22",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NC69-1",
                "protein_name": "BTB/POZ domain-containing protein KCTD6",
                "gene_name": "KCTD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y297-1",
                "protein_name": "F-box/WD repeat-containing protein 1A",
                "gene_name": "BTRC",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O14544-1",
                "protein_name": "Suppressor of cytokine signaling 6",
                "gene_name": "SOCS6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKB1-1",
                "protein_name": "F-box/WD repeat-containing protein 11",
                "gene_name": "FBXW11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25788-1",
                "protein_name": "Proteasome subunit alpha type-3",
                "gene_name": "PSMA3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8IWE4-1",
                "protein_name": "DCN1-like protein 3",
                "gene_name": "DCUN1D3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UH77-1",
                "protein_name": "Kelch-like protein 3",
                "gene_name": "KLHL3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q969P5-1",
                "protein_name": "F-box only protein 32",
                "gene_name": "FBXO32",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y3I1-1",
                "protein_name": "F-box only protein 7",
                "gene_name": "FBXO7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H469-1",
                "protein_name": "F-box/LRR-repeat protein 15",
                "gene_name": "FBXL15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96CD0-1",
                "protein_name": "F-box/LRR-repeat protein 8",
                "gene_name": "FBXL8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NEE6-1",
                "protein_name": "F-box and leucine-rich repeat protein 13",
                "gene_name": "FBXL13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKT7-1",
                "protein_name": "F-box/LRR-repeat protein 3",
                "gene_name": "FBXL3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96EF6-1",
                "protein_name": "F-box only protein 17",
                "gene_name": "FBXO17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UK22-1",
                "protein_name": "F-box only protein 2",
                "gene_name": "FBXO2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P57775-1",
                "protein_name": "F-box/WD repeat-containing protein 4",
                "gene_name": "FBXW4",
                "tax_name": "Human"
            },
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    {
        "title": "Protection against electrophile and oxidant stress by induction of the phase 2 response: fate of cysteines of the Keap1 sensor modified by inducers.",
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                "uniprot_canonical_ac": "P78396-1",
                "protein_name": "Cyclin-A1",
                "gene_name": "CCNA1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43303-1",
                "protein_name": "Centriolar coiled-coil protein of 110 kDa",
                "gene_name": "CCP110",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43242-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 3",
                "gene_name": "PSMD3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P14735-1",
                "protein_name": "Insulin-degrading enzyme",
                "gene_name": "IDE",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NQC7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase CYLD",
                "gene_name": "CYLD",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O95786-1",
                "protein_name": "Antiviral innate immune response receptor RIG-I",
                "gene_name": "DDX58; RIGI",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y265-1",
                "protein_name": "RuvB-like 1",
                "gene_name": "RUVBL1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UK80-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 21",
                "gene_name": "USP21",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6R327-1",
                "protein_name": "Rapamycin-insensitive companion of mTOR",
                "gene_name": "RICTOR",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NZL9-1",
                "protein_name": "Methionine adenosyltransferase 2 subunit beta",
                "gene_name": "MAT2B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92830-1",
                "protein_name": "Histone acetyltransferase KAT2A",
                "gene_name": "KAT2A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49721-1",
                "protein_name": "Proteasome subunit beta type-2",
                "gene_name": "PSMB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P20618-1",
                "protein_name": "Proteasome subunit beta type-1",
                "gene_name": "PSMB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43255-1",
                "protein_name": "E3 ubiquitin-protein ligase SIAH2",
                "gene_name": "SIAH2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43318-1",
                "protein_name": "Mitogen-activated protein kinase kinase kinase 7",
                "gene_name": "MAP3K7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8IXI2-1",
                "protein_name": "Mitochondrial Rho GTPase 1",
                "gene_name": "RHOT1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P54578-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 14",
                "gene_name": "USP14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86TJ2-1",
                "protein_name": "Transcriptional adapter 2-beta",
                "gene_name": "TADA2B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92466-1",
                "protein_name": "DNA damage-binding protein 2",
                "gene_name": "DDB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28070-1",
                "protein_name": "Proteasome subunit beta type-4",
                "gene_name": "PSMB4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UMW8-1",
                "protein_name": "Ubl carboxyl-terminal hydrolase 18",
                "gene_name": "USP18",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BVC4-1",
                "protein_name": "Target of rapamycin complex subunit LST8",
                "gene_name": "MLST8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9JJH3-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 10",
                "gene_name": "USP17L10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "A6NCW7-1",
                "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 4",
                "gene_name": "USP17L4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P45880-3",
                "protein_name": "Non-selective voltage-gated ion channel VDAC2",
                "gene_name": "VDAC2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P06746-1",
                "protein_name": "DNA polymerase beta",
                "gene_name": "POLB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P07550-1",
                "protein_name": "Beta-2 adrenergic receptor",
                "gene_name": "ADRB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0C0S8-1",
                "protein_name": "Histone H2A type 1",
                "gene_name": "H2AC11; H2AC13; H2AC15; H2AC16; H2AC17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P36897-1",
                "protein_name": "TGF-beta receptor type-1",
                "gene_name": "TGFBR1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15105-1",
                "protein_name": "SMAD family member 7",
                "gene_name": "SMAD7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P32121-1",
                "protein_name": "Beta-arrestin-2",
                "gene_name": "ARRB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H2K2-1",
                "protein_name": "Poly [ADP-ribose] polymerase tankyrase-2",
                "gene_name": "TNKS2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P51959-1",
                "protein_name": "Cyclin-G1",
                "gene_name": "CCNG1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25786-1",
                "protein_name": "Proteasome subunit alpha type-1",
                "gene_name": "PSMA1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49407-1",
                "protein_name": "Beta-arrestin-1",
                "gene_name": "ARRB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P31749-1",
                "protein_name": "RAC-alpha serine/threonine-protein kinase",
                "gene_name": "AKT1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P42345-1",
                "protein_name": "Serine/threonine-protein kinase mTOR",
                "gene_name": "MTOR",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P98177-1",
                "protein_name": "Forkhead box protein O4",
                "gene_name": "FOXO4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P17980-1",
                "protein_name": "26S proteasome regulatory subunit 6A",
                "gene_name": "PSMC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y2T1-1",
                "protein_name": "Axin-2",
                "gene_name": "AXIN2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P23771-1",
                "protein_name": "Trans-acting T-cell-specific transcription factor GATA-3",
                "gene_name": "GATA3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q16778-1",
                "protein_name": "Histone H2B type 2-E",
                "gene_name": "H2BC21",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15169-1",
                "protein_name": "Axin-1",
                "gene_name": "AXIN1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62807-1",
                "protein_name": "Histone H2B type 1-C/E/F/G/I",
                "gene_name": "H2BC10; H2BC4; H2BC6; H2BC7; H2BC8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P84022-1",
                "protein_name": "SMAD family member 3",
                "gene_name": "SMAD3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P31751-1",
                "protein_name": "RAC-beta serine/threonine-protein kinase",
                "gene_name": "AKT2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15797-1",
                "protein_name": "SMAD family member 1",
                "gene_name": "SMAD1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25788-1",
                "protein_name": "Proteasome subunit alpha type-3",
                "gene_name": "PSMA3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q14694-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 10",
                "gene_name": "USP10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9HAU4-1",
                "protein_name": "E3 ubiquitin-protein ligase SMURF2",
                "gene_name": "SMURF2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H0E7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 44",
                "gene_name": "USP44",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86UV5-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 48",
                "gene_name": "USP48",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6RBQ6-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 17",
                "gene_name": "USP17L17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q70CQ3-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 30",
                "gene_name": "USP30",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TEY7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 33",
                "gene_name": "USP33",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6RCP7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 19",
                "gene_name": "USP17L19",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9JLJ4-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 13",
                "gene_name": "USP17L13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6RJB6-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 20",
                "gene_name": "USP17L20",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15388-1",
                "protein_name": "Mitochondrial import receptor subunit TOM20 homolog",
                "gene_name": "TOMM20",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "A6NCW0-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 3",
                "gene_name": "USP17L3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "A8MUK1-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 5",
                "gene_name": "USP17L5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9J2P7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 15",
                "gene_name": "USP17L15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9JVI0-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 11",
                "gene_name": "USP17L11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6R9N7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 18",
                "gene_name": "USP17L18",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6RA61-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 22",
                "gene_name": "USP17L22",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0C7I0-1",
                "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 8",
                "gene_name": "USP17L8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6R901-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 21",
                "gene_name": "USP17L21",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q0WX57-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 24",
                "gene_name": "USP17L24; USP17L25; USP17L26; USP17L27; USP17L28; USP17L29; USP17L30",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P60900-1",
                "protein_name": "Proteasome subunit alpha type-6",
                "gene_name": "PSMA6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13490-1",
                "protein_name": "Baculoviral IAP repeat-containing protein 2",
                "gene_name": "BIRC2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62979-1",
                "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein",
                "gene_name": "RPS27A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P60484-1",
                "protein_name": "Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN",
                "gene_name": "PTEN",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P51784-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 11",
                "gene_name": "USP11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H7L9-1",
                "protein_name": "Sin3 histone deacetylase corepressor complex component SDS3",
                "gene_name": "SUDS3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01106-2",
                "protein_name": "Myc proto-oncogene protein",
                "gene_name": "MYC",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P21796-1",
                "protein_name": "Non-selective voltage-gated ion channel VDAC1",
                "gene_name": "VDAC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y4A5-1",
                "protein_name": "Transformation/transcription domain-associated protein",
                "gene_name": "TRRAP",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96FW1-1",
                "protein_name": "Ubiquitin thioesterase OTUB1",
                "gene_name": "OTUB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P13569-1",
                "protein_name": "Cystic fibrosis transmembrane conductance regulator",
                "gene_name": "CFTR",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13489-1",
                "protein_name": "Baculoviral IAP repeat-containing protein 3",
                "gene_name": "BIRC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5QNW6-1",
                "protein_name": "Histone H2B type 2-F",
                "gene_name": "H2BC18",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P33778-1",
                "protein_name": "Histone H2B type 1-B",
                "gene_name": "H2BC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P58876-1",
                "protein_name": "Histone H2B type 1-D",
                "gene_name": "H2BC5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96A08-1",
                "protein_name": "Histone H2B type 1-A",
                "gene_name": "H2BC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P23527-1",
                "protein_name": "Histone H2B type 1-O",
                "gene_name": "H2BC17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BVI0-1",
                "protein_name": "PHD finger protein 20",
                "gene_name": "PHF20",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BYX4-1",
                "protein_name": "Interferon-induced helicase C domain-containing protein 1",
                "gene_name": "IFIH1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UHP3-2",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 25",
                "gene_name": "USP25",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H9J4-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 42",
                "gene_name": "USP42",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P48556-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 8",
                "gene_name": "PSMD8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15008-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 6",
                "gene_name": "PSMD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28072-1",
                "protein_name": "Proteasome subunit beta type-6",
                "gene_name": "PSMB6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O00232-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 12",
                "gene_name": "PSMD12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25787-1",
                "protein_name": "Proteasome subunit alpha type-2",
                "gene_name": "PSMA2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28066-1",
                "protein_name": "Proteasome subunit alpha type-5",
                "gene_name": "PSMA5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5XPI4-1",
                "protein_name": "E3 ubiquitin-protein ligase RNF123",
                "gene_name": "RNF123",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q93008-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 9X",
                "gene_name": "USP9X",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O60814-1",
                "protein_name": "Histone H2B type 1-K",
                "gene_name": "H2BC12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q93077-1",
                "protein_name": "Histone H2A type 1-C",
                "gene_name": "H2AC6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q93079-1",
                "protein_name": "Histone H2B type 1-H",
                "gene_name": "H2BC9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96KK5-1",
                "protein_name": "Histone H2A type 1-H",
                "gene_name": "H2AC12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99879-1",
                "protein_name": "Histone H2B type 1-M",
                "gene_name": "H2BC14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y6I4-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 3",
                "gene_name": "USP3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96RU2-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 28",
                "gene_name": "USP28",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q70CQ2-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 34",
                "gene_name": "USP34",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O94826-1",
                "protein_name": "Mitochondrial import receptor subunit TOM70",
                "gene_name": "TOMM70",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86T82-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 37",
                "gene_name": "USP37",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BXU7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 26",
                "gene_name": "USP26",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6R6M4-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17",
                "gene_name": "USP17L2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7RTZ2-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 1",
                "gene_name": "USP17L1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9HBM6-1",
                "protein_name": "Transcription initiation factor TFIID subunit 9B",
                "gene_name": "TAF9B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y277-1",
                "protein_name": "Non-selective voltage-gated ion channel VDAC3",
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    {
        "title": "The TRAF6 ubiquitin ligase and TAK1 kinase mediate IKK activation by BCL10 and MALT1 in T lymphocytes.",
        "journal": "Molecular cell",
        "date": "2004",
        "authors": "Sun L, Deng L, Ea CK, Xia ZP, Chen ZJ",
        "reference": {
            "type": "PubMed",
            "id": "15125833",
            "url": "https://pubmed.ncbi.nlm.nih.gov/15125833"
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        "title": "Transforming growth factor-beta stimulates p300-dependent RUNX3 acetylation, which inhibits ubiquitination-mediated degradation.",
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    {
        "title": "iguana encodes a novel zinc-finger protein with coiled-coil domains essential for Hedgehog signal transduction in the zebrafish embryo.",
        "journal": "Genes &amp; development",
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        "authors": "Wolff C, Roy S, Lewis KE, Schauerte H, Joerg-Rauch G, Kirn A, Weiler C, Geisler R, Haffter P, Ingham PW",
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                "uniprot_canonical_ac": "P25789-1",
                "protein_name": "Proteasome subunit alpha type-4",
                "gene_name": "PSMA4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H2C0-1",
                "protein_name": "Gigaxonin",
                "gene_name": "GAN",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86XS8-1",
                "protein_name": "E3 ubiquitin-protein ligase RNF130",
                "gene_name": "RNF130",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15386-1",
                "protein_name": "Ubiquitin-protein ligase E3C",
                "gene_name": "UBE3C",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5VVX9-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 U",
                "gene_name": "UBE2U",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15345-2",
                "protein_name": "Leucine-rich repeat-containing protein 41",
                "gene_name": "LRRC41",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96MP8-1",
                "protein_name": "BTB/POZ domain-containing protein KCTD7",
                "gene_name": "KCTD7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9JR72-1",
                "protein_name": "Kelch repeat and BTB domain-containing protein 13",
                "gene_name": "KBTBD13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O94822-1",
                "protein_name": "E3 ubiquitin-protein ligase listerin",
                "gene_name": "LTN1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H0H3-1",
                "protein_name": "Kelch-like protein 25",
                "gene_name": "KLHL25",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UJP4-1",
                "protein_name": "Kelch-like protein 21",
                "gene_name": "KLHL21",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q2Q1W2-1",
                "protein_name": "E3 ubiquitin-protein ligase TRIM71",
                "gene_name": "TRIM71",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96L50-1",
                "protein_name": "Leucine-rich repeat protein 1",
                "gene_name": "LRR1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O60291-1",
                "protein_name": "E3 ubiquitin-protein ligase MGRN1",
                "gene_name": "MGRN1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62191-1",
                "protein_name": "26S proteasome regulatory subunit 4",
                "gene_name": "PSMC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BYM8-1",
                "protein_name": "RanBP-type and C3HC4-type zinc finger-containing protein 1",
                "gene_name": "RBCK1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H832-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 Z",
                "gene_name": "UBE2Z",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "A0AVT1-1",
                "protein_name": "Ubiquitin-like modifier-activating enzyme 6",
                "gene_name": "UBA6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49720-1",
                "protein_name": "Proteasome subunit beta type-3",
                "gene_name": "PSMB3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99460-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 1",
                "gene_name": "PSMD1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UNM6-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 13",
                "gene_name": "PSMD13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q969T4-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 E3",
                "gene_name": "UBE2E3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P51665-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 7",
                "gene_name": "PSMD7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13309-1",
                "protein_name": "S-phase kinase-associated protein 2",
                "gene_name": "SKP2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7Z7E8-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 Q1",
                "gene_name": "UBE2Q1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5U5Q3-1",
                "protein_name": "RNA-binding E3 ubiquitin-protein ligase MEX3C",
                "gene_name": "MEX3C",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96F44-1",
                "protein_name": "E3 ubiquitin-protein ligase TRIM11",
                "gene_name": "TRIM11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96AX9-1",
                "protein_name": "E3 ubiquitin-protein ligase MIB2",
                "gene_name": "MIB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28074-1",
                "protein_name": "Proteasome subunit beta type-5",
                "gene_name": "PSMB5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P35998-1",
                "protein_name": "26S proteasome regulatory subunit 7",
                "gene_name": "PSMC2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P43686-1",
                "protein_name": "26S proteasome regulatory subunit 6B",
                "gene_name": "PSMC4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99436-1",
                "protein_name": "Proteasome subunit beta type-7",
                "gene_name": "PSMB7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NVW2-1",
                "protein_name": "E3 ubiquitin-protein ligase RLIM",
                "gene_name": "RLIM",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q63HN8-3",
                "protein_name": "E3 ubiquitin-protein ligase RNF213",
                "gene_name": "RNF213",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5VTB9-1",
                "protein_name": "E3 ubiquitin-protein ligase RNF220",
                "gene_name": "RNF220",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6ZMZ0-1",
                "protein_name": "E3 ubiquitin-protein ligase RNF19B",
                "gene_name": "RNF19B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5XUX0-1",
                "protein_name": "F-box only protein 31",
                "gene_name": "FBXO31",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9C0C9-1",
                "protein_name": "(E3-independent) E2 ubiquitin-conjugating enzyme",
                "gene_name": "UBE2O",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15370-1",
                "protein_name": "Elongin-B",
                "gene_name": "ELOB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61077-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 D3",
                "gene_name": "UBE2D3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P51668-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 D1",
                "gene_name": "UBE2D1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXI3-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 10",
                "gene_name": "ASB10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13200-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 2",
                "gene_name": "PSMD2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXK1-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 15",
                "gene_name": "ASB15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H765-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 8",
                "gene_name": "ASB8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y576-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 1",
                "gene_name": "ASB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96NS5-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 16",
                "gene_name": "ASB16",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXH4-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 11",
                "gene_name": "ASB11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXJ9-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 17",
                "gene_name": "ASB17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXK3-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 13",
                "gene_name": "ASB13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXK4-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 12",
                "gene_name": "ASB12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NWX5-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 6",
                "gene_name": "ASB6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y575-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 3",
                "gene_name": "ASB3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96LR5-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 E2",
                "gene_name": "UBE2E2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O95352-1",
                "protein_name": "Ubiquitin-like modifier-activating enzyme ATG7",
                "gene_name": "ATG7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7Z419-1",
                "protein_name": "E3 ubiquitin-protein ligase RNF144B",
                "gene_name": "RNF144B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BV68-1",
                "protein_name": "E3 ubiquitin-protein ligase RNF126",
                "gene_name": "RNF126",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96J02-1",
                "protein_name": "E3 ubiquitin-protein ligase Itchy homolog",
                "gene_name": "ITCH",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62333-1",
                "protein_name": "26S proteasome regulatory subunit 10B",
                "gene_name": "PSMC6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WWX0-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 5",
                "gene_name": "ASB5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96DX5-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 9",
                "gene_name": "ASB9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43242-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 3",
                "gene_name": "PSMD3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q969H0-1",
                "protein_name": "F-box/WD repeat-containing protein 7",
                "gene_name": "FBXW7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q969Q1-1",
                "protein_name": "E3 ubiquitin-protein ligase TRIM63",
                "gene_name": "TRIM63",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WY64-1",
                "protein_name": "E3 ubiquitin-protein ligase MYLIP",
                "gene_name": "MYLIP",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q53GT1-1",
                "protein_name": "Kelch-like protein 22",
                "gene_name": "KLHL22",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y4B6-1",
                "protein_name": "DDB1- and CUL4-associated factor 1",
                "gene_name": "DCAF1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O60662-1",
                "protein_name": "Kelch-like protein 41",
                "gene_name": "KLHL41",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6Q0C0-1",
                "protein_name": "E3 ubiquitin-protein ligase TRAF7",
                "gene_name": "TRAF7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9P2J3-1",
                "protein_name": "Kelch-like protein 9",
                "gene_name": "KLHL9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6UWE0-1",
                "protein_name": "E3 ubiquitin-protein ligase LRSAM1",
                "gene_name": "LRSAM1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WWI1-1",
                "protein_name": "LIM domain only protein 7",
                "gene_name": "LMO7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NQ86-1",
                "protein_name": "E3 ubiquitin-protein ligase TRIM36",
                "gene_name": "TRIM36",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NVR0-1",
                "protein_name": "Kelch-like protein 11",
                "gene_name": "KLHL11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9P2N7-1",
                "protein_name": "Kelch-like protein 13",
                "gene_name": "KLHL13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49721-1",
                "protein_name": "Proteasome subunit beta type-2",
                "gene_name": "PSMB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P20618-1",
                "protein_name": "Proteasome subunit beta type-1",
                "gene_name": "PSMB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43255-1",
                "protein_name": "E3 ubiquitin-protein ligase SIAH2",
                "gene_name": "SIAH2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96PQ7-1",
                "protein_name": "Kelch-like protein 5",
                "gene_name": "KLHL5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96BH1-1",
                "protein_name": "E3 ubiquitin-protein ligase RNF25",
                "gene_name": "RNF25",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y6I7-1",
                "protein_name": "WD repeat and SOCS box-containing protein 1",
                "gene_name": "WSB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q14999-1",
                "protein_name": "Cullin-7",
                "gene_name": "CUL7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49427-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 R1",
                "gene_name": "CDC34",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62877-1",
                "protein_name": "E3 ubiquitin-protein ligase RBX1",
                "gene_name": "RBX1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61081-1",
                "protein_name": "NEDD8-conjugating enzyme Ubc12",
                "gene_name": "UBE2M",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28070-1",
                "protein_name": "Proteasome subunit beta type-4",
                "gene_name": "PSMB4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9GZZ9-1",
                "protein_name": "Ubiquitin-like modifier-activating enzyme 5",
                "gene_name": "UBA5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86V97-1",
                "protein_name": "Kelch repeat and BTB domain-containing protein 6",
                "gene_name": "KBTBD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WVZ9-1",
                "protein_name": "Kelch repeat and BTB domain-containing protein 7",
                "gene_name": "KBTBD7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62256-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 H",
                "gene_name": "UBE2H",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P41226-1",
                "protein_name": "Ubiquitin-like modifier-activating enzyme 7",
                "gene_name": "UBA7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q14139-1",
                "protein_name": "Ubiquitin conjugation factor E4 A",
                "gene_name": "UBE4A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96B02-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 W",
                "gene_name": "UBE2W",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9C037-1",
                "protein_name": "E3 ubiquitin-protein ligase TRIM4",
                "gene_name": "TRIM4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P29144-1",
                "protein_name": "Tripeptidyl-peptidase 2",
                "gene_name": "TPP2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13618-1",
                "protein_name": "Cullin-3",
                "gene_name": "CUL3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25786-1",
                "protein_name": "Proteasome subunit alpha type-1",
                "gene_name": "PSMA1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q17RB8-1",
                "protein_name": "LON peptidase N-terminal domain and RING finger protein 1",
                "gene_name": "LONRF1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q16763-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 S",
                "gene_name": "UBE2S",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P40337-1",
                "protein_name": "von Hippel-Lindau disease tumor suppressor",
                "gene_name": "VHL",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86Y13-1",
                "protein_name": "E3 ubiquitin-protein ligase DZIP3",
                "gene_name": "DZIP3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96BD6-1",
                "protein_name": "SPRY domain-containing SOCS box protein 1",
                "gene_name": "SPSB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BS18-1",
                "protein_name": "Anaphase-promoting complex subunit 13",
                "gene_name": "ANAPC13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P17980-1",
                "protein_name": "26S proteasome regulatory subunit 6A",
                "gene_name": "PSMC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99619-1",
                "protein_name": "SPRY domain-containing SOCS box protein 2",
                "gene_name": "SPSB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UM13-1",
                "protein_name": "Anaphase-promoting complex subunit 10",
                "gene_name": "ANAPC10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TBB1-1",
                "protein_name": "E3 ubiquitin-protein ligase LNX",
                "gene_name": "LNX1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WV44-1",
                "protein_name": "E3 ubiquitin-protein ligase TRIM41",
                "gene_name": "TRIM41",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UJX6-1",
                "protein_name": "Anaphase-promoting complex subunit 2",
                "gene_name": "ANAPC2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NC69-1",
                "protein_name": "BTB/POZ domain-containing protein KCTD6",
                "gene_name": "KCTD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UJX2-1",
                "protein_name": "Cell division cycle protein 23 homolog",
                "gene_name": "CDC23",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96PM5-1",
                "protein_name": "RING finger and CHY zinc finger domain-containing protein 1",
                "gene_name": "RCHY1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NYG5-1",
                "protein_name": "Anaphase-promoting complex subunit 11",
                "gene_name": "ANAPC11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y297-1",
                "protein_name": "F-box/WD repeat-containing protein 1A",
                "gene_name": "BTRC",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O60260-1",
                "protein_name": "E3 ubiquitin-protein ligase parkin",
                "gene_name": "PRKN",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKB1-1",
                "protein_name": "F-box/WD repeat-containing protein 11",
                "gene_name": "FBXW11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9C026-1",
                "protein_name": "E3 ubiquitin-protein ligase TRIM9",
                "gene_name": "TRIM9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UBS8-1",
                "protein_name": "E3 ubiquitin-protein ligase RNF14",
                "gene_name": "RNF14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P30260-1",
                "protein_name": "Cell division cycle protein 27 homolog",
                "gene_name": "CDC27",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25788-1",
                "protein_name": "Proteasome subunit alpha type-3",
                "gene_name": "PSMA3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H0M0-1",
                "protein_name": "NEDD4-like E3 ubiquitin-protein ligase WWP1",
                "gene_name": "WWP1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UH77-1",
                "protein_name": "Kelch-like protein 3",
                "gene_name": "KLHL3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q969P5-1",
                "protein_name": "F-box only protein 32",
                "gene_name": "FBXO32",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y3I1-1",
                "protein_name": "F-box only protein 7",
                "gene_name": "FBXO7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9HCE7-1",
                "protein_name": "E3 ubiquitin-protein ligase SMURF1",
                "gene_name": "SMURF1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H469-1",
                "protein_name": "F-box/LRR-repeat protein 15",
                "gene_name": "FBXL15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96CD0-1",
                "protein_name": "F-box/LRR-repeat protein 8",
                "gene_name": "FBXL8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NEE6-1",
                "protein_name": "F-box and leucine-rich repeat protein 13",
                "gene_name": "FBXL13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKT7-1",
                "protein_name": "F-box/LRR-repeat protein 3",
                "gene_name": "FBXL3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96EF6-1",
                "protein_name": "F-box only protein 17",
                "gene_name": "FBXO17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UK22-1",
                "protein_name": "F-box only protein 2",
                "gene_name": "FBXO2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P57775-1",
                "protein_name": "F-box/WD repeat-containing protein 4",
                "gene_name": "FBXW4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N1E6-1",
                "protein_name": "F-box/LRR-repeat protein 14",
                "gene_name": "FBXL14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96ME1-4",
                "protein_name": "F-box/LRR-repeat protein 18",
                "gene_name": "FBXL18",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UJT9-1",
                "protein_name": "F-box/LRR-repeat protein 7",
                "gene_name": "FBXL7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKT6-1",
                "protein_name": "Putative F-box/LRR-repeat protein 21",
                "gene_name": "FBXL21P",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9HAU4-1",
                "protein_name": "E3 ubiquitin-protein ligase SMURF2",
                "gene_name": "SMURF2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O14543-1",
                "protein_name": "Suppressor of cytokine signaling 3",
                "gene_name": "SOCS3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N2K1-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 J2",
                "gene_name": "UBE2J2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O00762-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 C",
                "gene_name": "UBE2C",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WVN8-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 Q2",
                "gene_name": "UBE2Q2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q969U6-1",
                "protein_name": "F-box/WD repeat-containing protein 5",
                "gene_name": "FBXW5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86XK2-1",
                "protein_name": "F-box only protein 11",
                "gene_name": "FBXO11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P60900-1",
                "protein_name": "Proteasome subunit alpha type-6",
                "gene_name": "PSMA6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62979-1",
                "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein",
                "gene_name": "RPS27A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H4M3-1",
                "protein_name": "F-box only protein 44",
                "gene_name": "FBXO44",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96KE9-3",
                "protein_name": "BTB/POZ domain-containing protein 6",
                "gene_name": "BTBD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61088-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 N",
                "gene_name": "UBE2N",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13617-1",
                "protein_name": "Cullin-2",
                "gene_name": "CUL2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6ZNA4-1",
                "protein_name": "E3 ubiquitin-protein ligase Arkadia",
                "gene_name": "RNF111",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P51965-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 E1",
                "gene_name": "UBE2E1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62837-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 D2",
                "gene_name": "UBE2D2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H0C5-1",
                "protein_name": "BTB/POZ domain-containing protein 1",
                "gene_name": "BTBD1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UII4-1",
                "protein_name": "E3 ISG15--protein ligase HERC5",
                "gene_name": "HERC5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15751-1",
                "protein_name": "Probable E3 ubiquitin-protein ligase HERC1",
                "gene_name": "HERC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5T447-1",
                "protein_name": "E3 ubiquitin-protein ligase HECTD3",
                "gene_name": "HECTD3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q05086-1",
                "protein_name": "Ubiquitin-protein ligase E3A",
                "gene_name": "UBE3A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43164-1",
                "protein_name": "E3 ubiquitin-protein ligase Praja-2",
                "gene_name": "PJA2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86XT4-1",
                "protein_name": "E3 ubiquitin-protein ligase TRIM50",
                "gene_name": "TRIM50",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P55786-1",
                "protein_name": "Puromycin-sensitive aminopeptidase",
                "gene_name": "NPEPPS",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P78317-1",
                "protein_name": "E3 ubiquitin-protein ligase RNF4",
                "gene_name": "RNF4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49459-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 A",
                "gene_name": "UBE2A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P48556-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 8",
                "gene_name": "PSMD8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15008-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 6",
                "gene_name": "PSMD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28072-1",
                "protein_name": "Proteasome subunit beta type-6",
                "gene_name": "PSMB6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O00232-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 12",
                "gene_name": "PSMD12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7Z6E9-1",
                "protein_name": "E3 ubiquitin-protein ligase RBBP6",
                "gene_name": "RBBP6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25787-1",
                "protein_name": "Proteasome subunit alpha type-2",
                "gene_name": "PSMA2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28066-1",
                "protein_name": "Proteasome subunit alpha type-5",
                "gene_name": "PSMA5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5XPI4-1",
                "protein_name": "E3 ubiquitin-protein ligase RNF123",
                "gene_name": "RNF123",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9ULT8-1",
                "protein_name": "E3 ubiquitin-protein ligase HECTD1",
                "gene_name": "HECTD1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NCQ5-1",
                "protein_name": "F-box only protein 15",
                "gene_name": "FBXO15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5GLZ8-1",
                "protein_name": "Probable E3 ubiquitin-protein ligase HERC4",
                "gene_name": "HERC4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8IVU3-1",
                "protein_name": "Probable E3 ubiquitin-protein ligase HERC6",
                "gene_name": "HERC6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UK96-1",
                "protein_name": "F-box only protein 10",
                "gene_name": "FBXO10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P63146-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 B",
                "gene_name": "UBE2B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5U5R9-1",
                "protein_name": "Probable E3 ubiquitin-protein ligase HECTD2",
                "gene_name": "HECTD2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TB52-1",
                "protein_name": "F-box only protein 30",
                "gene_name": "FBXO30",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UH90-1",
                "protein_name": "F-box only protein 40",
                "gene_name": "FBXO40",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7Z6J0-1",
                "protein_name": "E3 ubiquitin-protein ligase SH3RF1",
                "gene_name": "SH3RF1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H9P5-4",
                "protein_name": "Putative E3 ubiquitin-protein ligase UNKL",
                "gene_name": "UNKL",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8IWV7-1",
                "protein_name": "E3 ubiquitin-protein ligase UBR1",
                "gene_name": "UBR1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q969M7-1",
                "protein_name": "NEDD8-conjugating enzyme UBE2F",
                "gene_name": "UBE2F-SCLY; UBE2F",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15819-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 variant 2",
                "gene_name": "UBE2V2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62253-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 G1",
                "gene_name": "UBE2G1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7Z6J8-1",
                "protein_name": "E3 ubiquitin-protein ligase E3D",
                "gene_name": "UBE3D",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8ND25-1",
                "protein_name": "E3 ubiquitin-protein ligase ZNRF1",
                "gene_name": "ZNRF1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8IWV8-1",
                "protein_name": "E3 ubiquitin-protein ligase UBR2",
                "gene_name": "UBR2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5T4S7-1",
                "protein_name": "E3 ubiquitin-protein ligase UBR4",
                "gene_name": "UBR4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y385-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 J1",
                "gene_name": "UBE2J1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N7E2-1",
                "protein_name": "E3 ubiquitin-protein ligase CBLL2",
                "gene_name": "CBLL2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NHG8-1",
                "protein_name": "E3 ubiquitin-protein ligase ZNRF2",
                "gene_name": "ZNRF2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O95198-1",
                "protein_name": "Kelch-like protein 2",
                "gene_name": "KLHL2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13042-1",
                "protein_name": "Cell division cycle protein 16 homolog",
                "gene_name": "CDC16",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9HCM9-1",
                "protein_name": "E3 ubiquitin-protein ligase TRIM39",
                "gene_name": "TRIM39",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UM11-1",
                "protein_name": "Fizzy-related protein homolog",
                "gene_name": "FZR1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NXK8-1",
                "protein_name": "F-box/LRR-repeat protein 12",
                "gene_name": "FBXL12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P19474-1",
                "protein_name": "E3 ubiquitin-protein ligase TRIM21",
                "gene_name": "TRIM21",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0CG47-1",
                "protein_name": "Polyubiquitin-B",
                "gene_name": "UBB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKT8-1",
                "protein_name": "F-box/WD repeat-containing protein 2",
                "gene_name": "FBXW2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NHZ8-1",
                "protein_name": "Anaphase-promoting complex subunit CDC26",
                "gene_name": "CDC26",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96PU5-1",
                "protein_name": "E3 ubiquitin-protein ligase NEDD4-like",
                "gene_name": "NEDD4L",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UHC7-1",
                "protein_name": "E3 ubiquitin-protein ligase makorin-1",
                "gene_name": "MKRN1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BSL1-1",
                "protein_name": "Ubiquitin-associated domain-containing protein 1",
                "gene_name": "UBAC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62987-1",
                "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein",
                "gene_name": "UBA52",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y2X8-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 D4",
                "gene_name": "UBE2D4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TDB6-1",
                "protein_name": "E3 ubiquitin-protein ligase DTX3L",
                "gene_name": "DTX3L",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y4L5-1",
                "protein_name": "E3 ubiquitin-protein ligase RNF115",
                "gene_name": "RNF115",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O00487-1",
                "protein_name": "Ubiquitin C-terminal hydrolase PSMD14",
                "gene_name": "PSMD14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O94952-2",
                "protein_name": "F-box only protein 21",
                "gene_name": "FBXO21",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UIQ6-1",
                "protein_name": "Leucyl-cystinyl aminopeptidase",
                "gene_name": "LNPEP",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TF61-1",
                "protein_name": "F-box only protein 41",
                "gene_name": "FBXO41",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96IG2-1",
                "protein_name": "F-box/LRR-repeat protein 20",
                "gene_name": "FBXL20",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NFY9-1",
                "protein_name": "Kelch repeat and BTB domain-containing protein 8",
                "gene_name": "KBTBD8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O95714-1",
                "protein_name": "E3 ubiquitin-protein ligase HERC2",
                "gene_name": "HERC2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15034-1",
                "protein_name": "Probable E3 ubiquitin-protein ligase HERC3",
                "gene_name": "HERC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8IYU2-1",
                "protein_name": "E3 ubiquitin-protein ligase HACE1",
                "gene_name": "HACE1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13404-4",
                "protein_name": "Ubiquitin-conjugating enzyme E2 variant 1",
                "gene_name": "UBE2V1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9P2P5-1",
                "protein_name": "E3 ubiquitin-protein ligase HECW2",
                "gene_name": "HECW2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NG27-1",
                "protein_name": "E3 ubiquitin-protein ligase Praja-1",
                "gene_name": "PJA1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BWF2-1",
                "protein_name": "E3 ubiquitin-protein ligase TRAIP",
                "gene_name": "TRAIP",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O94941-1",
                "protein_name": "RING finger protein 37",
                "gene_name": "UBOX5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6X9E4-1",
                "protein_name": "F-box/WD repeat-containing protein 12",
                "gene_name": "FBXW12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5XX13-1",
                "protein_name": "F-box/WD repeat-containing protein 10",
                "gene_name": "FBXW10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O94874-1",
                "protein_name": "E3 UFM1-protein ligase 1",
                "gene_name": "UFL1",
                "tax_name": "Human"
            },
            {
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                "protein_name": "RanBP-type and C3HC4-type zinc finger-containing protein 1",
                "gene_name": "RBCK1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H832-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 Z",
                "gene_name": "UBE2Z",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "A0AVT1-1",
                "protein_name": "Ubiquitin-like modifier-activating enzyme 6",
                "gene_name": "UBA6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49720-1",
                "protein_name": "Proteasome subunit beta type-3",
                "gene_name": "PSMB3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99460-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 1",
                "gene_name": "PSMD1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UNM6-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 13",
                "gene_name": "PSMD13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q969T4-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 E3",
                "gene_name": "UBE2E3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P51665-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 7",
                "gene_name": "PSMD7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13309-1",
                "protein_name": "S-phase kinase-associated protein 2",
                "gene_name": "SKP2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7Z7E8-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 Q1",
                "gene_name": "UBE2Q1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5U5Q3-1",
                "protein_name": "RNA-binding E3 ubiquitin-protein ligase MEX3C",
                "gene_name": "MEX3C",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96F44-1",
                "protein_name": "E3 ubiquitin-protein ligase TRIM11",
                "gene_name": "TRIM11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96AX9-1",
                "protein_name": "E3 ubiquitin-protein ligase MIB2",
                "gene_name": "MIB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28074-1",
                "protein_name": "Proteasome subunit beta type-5",
                "gene_name": "PSMB5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P35998-1",
                "protein_name": "26S proteasome regulatory subunit 7",
                "gene_name": "PSMC2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P43686-1",
                "protein_name": "26S proteasome regulatory subunit 6B",
                "gene_name": "PSMC4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99436-1",
                "protein_name": "Proteasome subunit beta type-7",
                "gene_name": "PSMB7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NVW2-1",
                "protein_name": "E3 ubiquitin-protein ligase RLIM",
                "gene_name": "RLIM",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q63HN8-3",
                "protein_name": "E3 ubiquitin-protein ligase RNF213",
                "gene_name": "RNF213",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5VTB9-1",
                "protein_name": "E3 ubiquitin-protein ligase RNF220",
                "gene_name": "RNF220",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6ZMZ0-1",
                "protein_name": "E3 ubiquitin-protein ligase RNF19B",
                "gene_name": "RNF19B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5XUX0-1",
                "protein_name": "F-box only protein 31",
                "gene_name": "FBXO31",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9C0C9-1",
                "protein_name": "(E3-independent) E2 ubiquitin-conjugating enzyme",
                "gene_name": "UBE2O",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15370-1",
                "protein_name": "Elongin-B",
                "gene_name": "ELOB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61077-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 D3",
                "gene_name": "UBE2D3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P51668-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 D1",
                "gene_name": "UBE2D1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXI3-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 10",
                "gene_name": "ASB10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13200-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 2",
                "gene_name": "PSMD2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXK1-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 15",
                "gene_name": "ASB15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H765-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 8",
                "gene_name": "ASB8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y576-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 1",
                "gene_name": "ASB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96NS5-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 16",
                "gene_name": "ASB16",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXH4-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 11",
                "gene_name": "ASB11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXJ9-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 17",
                "gene_name": "ASB17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXK3-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 13",
                "gene_name": "ASB13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXK4-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 12",
                "gene_name": "ASB12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NWX5-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 6",
                "gene_name": "ASB6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y575-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 3",
                "gene_name": "ASB3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96LR5-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 E2",
                "gene_name": "UBE2E2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O95352-1",
                "protein_name": "Ubiquitin-like modifier-activating enzyme ATG7",
                "gene_name": "ATG7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7Z419-1",
                "protein_name": "E3 ubiquitin-protein ligase RNF144B",
                "gene_name": "RNF144B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BV68-1",
                "protein_name": "E3 ubiquitin-protein ligase RNF126",
                "gene_name": "RNF126",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96J02-1",
                "protein_name": "E3 ubiquitin-protein ligase Itchy homolog",
                "gene_name": "ITCH",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62333-1",
                "protein_name": "26S proteasome regulatory subunit 10B",
                "gene_name": "PSMC6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WWX0-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 5",
                "gene_name": "ASB5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96DX5-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 9",
                "gene_name": "ASB9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43242-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 3",
                "gene_name": "PSMD3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q969H0-1",
                "protein_name": "F-box/WD repeat-containing protein 7",
                "gene_name": "FBXW7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q969Q1-1",
                "protein_name": "E3 ubiquitin-protein ligase TRIM63",
                "gene_name": "TRIM63",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WY64-1",
                "protein_name": "E3 ubiquitin-protein ligase MYLIP",
                "gene_name": "MYLIP",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q53GT1-1",
                "protein_name": "Kelch-like protein 22",
                "gene_name": "KLHL22",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y4B6-1",
                "protein_name": "DDB1- and CUL4-associated factor 1",
                "gene_name": "DCAF1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O60662-1",
                "protein_name": "Kelch-like protein 41",
                "gene_name": "KLHL41",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6Q0C0-1",
                "protein_name": "E3 ubiquitin-protein ligase TRAF7",
                "gene_name": "TRAF7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9P2J3-1",
                "protein_name": "Kelch-like protein 9",
                "gene_name": "KLHL9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6UWE0-1",
                "protein_name": "E3 ubiquitin-protein ligase LRSAM1",
                "gene_name": "LRSAM1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WWI1-1",
                "protein_name": "LIM domain only protein 7",
                "gene_name": "LMO7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NQ86-1",
                "protein_name": "E3 ubiquitin-protein ligase TRIM36",
                "gene_name": "TRIM36",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NVR0-1",
                "protein_name": "Kelch-like protein 11",
                "gene_name": "KLHL11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9P2N7-1",
                "protein_name": "Kelch-like protein 13",
                "gene_name": "KLHL13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49721-1",
                "protein_name": "Proteasome subunit beta type-2",
                "gene_name": "PSMB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P20618-1",
                "protein_name": "Proteasome subunit beta type-1",
                "gene_name": "PSMB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43255-1",
                "protein_name": "E3 ubiquitin-protein ligase SIAH2",
                "gene_name": "SIAH2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96PQ7-1",
                "protein_name": "Kelch-like protein 5",
                "gene_name": "KLHL5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96BH1-1",
                "protein_name": "E3 ubiquitin-protein ligase RNF25",
                "gene_name": "RNF25",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y6I7-1",
                "protein_name": "WD repeat and SOCS box-containing protein 1",
                "gene_name": "WSB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q14999-1",
                "protein_name": "Cullin-7",
                "gene_name": "CUL7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49427-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 R1",
                "gene_name": "CDC34",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62877-1",
                "protein_name": "E3 ubiquitin-protein ligase RBX1",
                "gene_name": "RBX1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61081-1",
                "protein_name": "NEDD8-conjugating enzyme Ubc12",
                "gene_name": "UBE2M",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28070-1",
                "protein_name": "Proteasome subunit beta type-4",
                "gene_name": "PSMB4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9GZZ9-1",
                "protein_name": "Ubiquitin-like modifier-activating enzyme 5",
                "gene_name": "UBA5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86V97-1",
                "protein_name": "Kelch repeat and BTB domain-containing protein 6",
                "gene_name": "KBTBD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WVZ9-1",
                "protein_name": "Kelch repeat and BTB domain-containing protein 7",
                "gene_name": "KBTBD7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62256-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 H",
                "gene_name": "UBE2H",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P41226-1",
                "protein_name": "Ubiquitin-like modifier-activating enzyme 7",
                "gene_name": "UBA7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q14139-1",
                "protein_name": "Ubiquitin conjugation factor E4 A",
                "gene_name": "UBE4A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96B02-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 W",
                "gene_name": "UBE2W",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9C037-1",
                "protein_name": "E3 ubiquitin-protein ligase TRIM4",
                "gene_name": "TRIM4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P29144-1",
                "protein_name": "Tripeptidyl-peptidase 2",
                "gene_name": "TPP2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13618-1",
                "protein_name": "Cullin-3",
                "gene_name": "CUL3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25786-1",
                "protein_name": "Proteasome subunit alpha type-1",
                "gene_name": "PSMA1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q17RB8-1",
                "protein_name": "LON peptidase N-terminal domain and RING finger protein 1",
                "gene_name": "LONRF1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q16763-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 S",
                "gene_name": "UBE2S",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P40337-1",
                "protein_name": "von Hippel-Lindau disease tumor suppressor",
                "gene_name": "VHL",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86Y13-1",
                "protein_name": "E3 ubiquitin-protein ligase DZIP3",
                "gene_name": "DZIP3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96BD6-1",
                "protein_name": "SPRY domain-containing SOCS box protein 1",
                "gene_name": "SPSB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BS18-1",
                "protein_name": "Anaphase-promoting complex subunit 13",
                "gene_name": "ANAPC13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P17980-1",
                "protein_name": "26S proteasome regulatory subunit 6A",
                "gene_name": "PSMC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99619-1",
                "protein_name": "SPRY domain-containing SOCS box protein 2",
                "gene_name": "SPSB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UM13-1",
                "protein_name": "Anaphase-promoting complex subunit 10",
                "gene_name": "ANAPC10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TBB1-1",
                "protein_name": "E3 ubiquitin-protein ligase LNX",
                "gene_name": "LNX1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WV44-1",
                "protein_name": "E3 ubiquitin-protein ligase TRIM41",
                "gene_name": "TRIM41",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UJX6-1",
                "protein_name": "Anaphase-promoting complex subunit 2",
                "gene_name": "ANAPC2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NC69-1",
                "protein_name": "BTB/POZ domain-containing protein KCTD6",
                "gene_name": "KCTD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UJX2-1",
                "protein_name": "Cell division cycle protein 23 homolog",
                "gene_name": "CDC23",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96PM5-1",
                "protein_name": "RING finger and CHY zinc finger domain-containing protein 1",
                "gene_name": "RCHY1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NYG5-1",
                "protein_name": "Anaphase-promoting complex subunit 11",
                "gene_name": "ANAPC11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y297-1",
                "protein_name": "F-box/WD repeat-containing protein 1A",
                "gene_name": "BTRC",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O60260-1",
                "protein_name": "E3 ubiquitin-protein ligase parkin",
                "gene_name": "PRKN",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKB1-1",
                "protein_name": "F-box/WD repeat-containing protein 11",
                "gene_name": "FBXW11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9C026-1",
                "protein_name": "E3 ubiquitin-protein ligase TRIM9",
                "gene_name": "TRIM9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UBS8-1",
                "protein_name": "E3 ubiquitin-protein ligase RNF14",
                "gene_name": "RNF14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P30260-1",
                "protein_name": "Cell division cycle protein 27 homolog",
                "gene_name": "CDC27",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25788-1",
                "protein_name": "Proteasome subunit alpha type-3",
                "gene_name": "PSMA3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H0M0-1",
                "protein_name": "NEDD4-like E3 ubiquitin-protein ligase WWP1",
                "gene_name": "WWP1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UH77-1",
                "protein_name": "Kelch-like protein 3",
                "gene_name": "KLHL3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q969P5-1",
                "protein_name": "F-box only protein 32",
                "gene_name": "FBXO32",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y3I1-1",
                "protein_name": "F-box only protein 7",
                "gene_name": "FBXO7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9HCE7-1",
                "protein_name": "E3 ubiquitin-protein ligase SMURF1",
                "gene_name": "SMURF1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H469-1",
                "protein_name": "F-box/LRR-repeat protein 15",
                "gene_name": "FBXL15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96CD0-1",
                "protein_name": "F-box/LRR-repeat protein 8",
                "gene_name": "FBXL8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NEE6-1",
                "protein_name": "F-box and leucine-rich repeat protein 13",
                "gene_name": "FBXL13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKT7-1",
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            {
                "uniprot_canonical_ac": "Q8IVU3-1",
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            },
            {
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            },
            {
                "uniprot_canonical_ac": "Q8TB52-1",
                "protein_name": "F-box only protein 30",
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                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UH90-1",
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            },
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            },
            {
                "uniprot_canonical_ac": "P62253-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 G1",
                "gene_name": "UBE2G1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7Z6J8-1",
                "protein_name": "E3 ubiquitin-protein ligase E3D",
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                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8ND25-1",
                "protein_name": "E3 ubiquitin-protein ligase ZNRF1",
                "gene_name": "ZNRF1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8IWV8-1",
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            },
            {
                "uniprot_canonical_ac": "Q5T4S7-1",
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            },
            {
                "uniprot_canonical_ac": "Q8N7E2-1",
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                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "Q8NHG8-1",
                "protein_name": "E3 ubiquitin-protein ligase ZNRF2",
                "gene_name": "ZNRF2",
                "tax_name": "Human"
            },
            {
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            },
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            {
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            },
            {
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                "gene_name": "FZR1",
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            {
                "uniprot_canonical_ac": "Q9NXK8-1",
                "protein_name": "F-box/LRR-repeat protein 12",
                "gene_name": "FBXL12",
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            },
            {
                "uniprot_canonical_ac": "P19474-1",
                "protein_name": "E3 ubiquitin-protein ligase TRIM21",
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            },
            {
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            },
            {
                "uniprot_canonical_ac": "Q9UKT8-1",
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            },
            {
                "uniprot_canonical_ac": "Q8NHZ8-1",
                "protein_name": "Anaphase-promoting complex subunit CDC26",
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                "uniprot_canonical_ac": "Q96PU5-1",
                "protein_name": "E3 ubiquitin-protein ligase NEDD4-like",
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            {
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            },
            {
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            },
            {
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                "protein_name": "Leucyl-cystinyl aminopeptidase",
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            },
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            },
            {
                "uniprot_canonical_ac": "O95714-1",
                "protein_name": "E3 ubiquitin-protein ligase HERC2",
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            },
            {
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            },
            {
                "uniprot_canonical_ac": "Q8IYU2-1",
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            },
            {
                "uniprot_canonical_ac": "Q13404-4",
                "protein_name": "Ubiquitin-conjugating enzyme E2 variant 1",
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            },
            {
                "uniprot_canonical_ac": "Q9P2P5-1",
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                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NG27-1",
                "protein_name": "E3 ubiquitin-protein ligase Praja-1",
                "gene_name": "PJA1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BWF2-1",
                "protein_name": "E3 ubiquitin-protein ligase TRAIP",
                "gene_name": "TRAIP",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O94941-1",
                "protein_name": "RING finger protein 37",
                "gene_name": "UBOX5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6X9E4-1",
                "protein_name": "F-box/WD repeat-containing protein 12",
                "gene_name": "FBXW12",
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            {
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            },
            {
                "uniprot_canonical_ac": "O94874-1",
                "protein_name": "E3 UFM1-protein ligase 1",
                "gene_name": "UFL1",
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            },
            {
                "uniprot_canonical_ac": "Q7Z3V4-1",
                "protein_name": "Ubiquitin-protein ligase E3B",
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                "uniprot_canonical_ac": "Q8IUQ4-1",
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            },
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                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q14145-1",
                "protein_name": "Kelch-like ECH-associated protein 1",
                "gene_name": "KEAP1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P63208-1",
                "protein_name": "S-phase kinase-associated protein 1",
                "gene_name": "SKP1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13049-1",
                "protein_name": "E3 ubiquitin-protein ligase TRIM32",
                "gene_name": "TRIM32",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKT5-1",
                "protein_name": "F-box only protein 4",
                "gene_name": "FBXO4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UNE7-1",
                "protein_name": "E3 ubiquitin-protein ligase CHIP",
                "gene_name": "STUB1",
                "tax_name": "Human"
            }
        ],
        "species": [
            {
                "name": "Homo sapiens",
                "taxid": 9606,
                "evidence": [
                    {
                        "database": "UniProtKB",
                        "id": "O14818",
                        "url": "https://www.uniprot.org/uniprotkb/O14818"
                    }
                ],
                "common_name": "Human",
                "glygen_name": "Human",
                "reference_species": "Homo sapiens [9606]"
            }
        ],
        "record_id": "pubmed.15224092",
        "abstract": "",
        "glycosylation": [],
        "mutagenesis": [],
        "snv": [],
        "phosphorylation": [],
        "glycation": [],
        "section_stats": [
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                "uniprot_canonical_ac": "Q6ZVZ8-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 18",
                "gene_name": "ASB18",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TAT6-1",
                "protein_name": "Nuclear protein localization protein 4 homolog",
                "gene_name": "NPLOC4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92890-2",
                "protein_name": "Ubiquitin recognition factor in ER-associated degradation protein 1",
                "gene_name": "UFD1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P41002-1",
                "protein_name": "Cyclin-F",
                "gene_name": "CCNF",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q05516-1",
                "protein_name": "Zinc finger and BTB domain-containing protein 16",
                "gene_name": "ZBTB16",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15369-1",
                "protein_name": "Elongin-C",
                "gene_name": "ELOC",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8IWT3-1",
                "protein_name": "Cullin-9",
                "gene_name": "CUL9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TBC4-1",
                "protein_name": "NEDD8-activating enzyme E1 catalytic subunit",
                "gene_name": "UBA3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13216-1",
                "protein_name": "DNA excision repair protein ERCC-8",
                "gene_name": "ERCC8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62195-1",
                "protein_name": "26S proteasome regulatory subunit 8",
                "gene_name": "PSMC5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q16576-1",
                "protein_name": "Histone-binding protein RBBP7",
                "gene_name": "RBBP7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NI29-1",
                "protein_name": "F-box only protein 27",
                "gene_name": "FBXO27",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6P050-1",
                "protein_name": "F-box and leucine-rich protein 22",
                "gene_name": "FBXL22",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NEZ5-1",
                "protein_name": "F-box only protein 22",
                "gene_name": "FBXO22",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NRD1-1",
                "protein_name": "F-box only protein 6",
                "gene_name": "FBXO6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5XUX1-3",
                "protein_name": "F-box/WD repeat-containing protein 9",
                "gene_name": "FBXW9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N3Y1-1",
                "protein_name": "F-box/WD repeat-containing protein 8",
                "gene_name": "FBXW8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UK97-1",
                "protein_name": "F-box only protein 9",
                "gene_name": "FBXO9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKA1-1",
                "protein_name": "F-box/LRR-repeat protein 5",
                "gene_name": "FBXL5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKA2-1",
                "protein_name": "F-box/LRR-repeat protein 4",
                "gene_name": "FBXL4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6PCT2-1",
                "protein_name": "F-box/LRR-repeat protein 19",
                "gene_name": "FBXL19",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N461-1",
                "protein_name": "F-box/LRR-repeat protein 16",
                "gene_name": "FBXL16",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25789-1",
                "protein_name": "Proteasome subunit alpha type-4",
                "gene_name": "PSMA4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H2C0-1",
                "protein_name": "Gigaxonin",
                "gene_name": "GAN",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15345-2",
                "protein_name": "Leucine-rich repeat-containing protein 41",
                "gene_name": "LRRC41",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96MP8-1",
                "protein_name": "BTB/POZ domain-containing protein KCTD7",
                "gene_name": "KCTD7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9JR72-1",
                "protein_name": "Kelch repeat and BTB domain-containing protein 13",
                "gene_name": "KBTBD13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H0H3-1",
                "protein_name": "Kelch-like protein 25",
                "gene_name": "KLHL25",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UJP4-1",
                "protein_name": "Kelch-like protein 21",
                "gene_name": "KLHL21",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96L50-1",
                "protein_name": "Leucine-rich repeat protein 1",
                "gene_name": "LRR1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62191-1",
                "protein_name": "26S proteasome regulatory subunit 4",
                "gene_name": "PSMC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UBW8-1",
                "protein_name": "COP9 signalosome complex subunit 7a",
                "gene_name": "COPS7A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99627-1",
                "protein_name": "COP9 signalosome complex subunit 8",
                "gene_name": "COPS8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O75147-3",
                "protein_name": "Obscurin-like protein 1",
                "gene_name": "OBSL1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49720-1",
                "protein_name": "Proteasome subunit beta type-3",
                "gene_name": "PSMB3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99460-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 1",
                "gene_name": "PSMD1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UNM6-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 13",
                "gene_name": "PSMD13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P51665-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 7",
                "gene_name": "PSMD7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NSE2-1",
                "protein_name": "Cytokine-inducible SH2-containing protein",
                "gene_name": "CISH",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13309-1",
                "protein_name": "S-phase kinase-associated protein 2",
                "gene_name": "SKP2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q60795-1",
                "protein_name": "Nuclear factor erythroid 2-related factor 2",
                "gene_name": "Nfe2l2",
                "tax_name": "Mouse"
            },
            {
                "uniprot_canonical_ac": "Q9Z2X8-1",
                "protein_name": "Kelch-like ECH-associated protein 1",
                "gene_name": "Keap1",
                "tax_name": "Mouse"
            },
            {
                "uniprot_canonical_ac": "Q9BR09-1",
                "protein_name": "Neuralized-like protein 2",
                "gene_name": "NEURL2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28074-1",
                "protein_name": "Proteasome subunit beta type-5",
                "gene_name": "PSMB5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P35998-1",
                "protein_name": "26S proteasome regulatory subunit 7",
                "gene_name": "PSMC2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P43686-1",
                "protein_name": "26S proteasome regulatory subunit 6B",
                "gene_name": "PSMC4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99436-1",
                "protein_name": "Proteasome subunit beta type-7",
                "gene_name": "PSMB7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9JLV5-1",
                "protein_name": "Cullin-3",
                "gene_name": "Cul3",
                "tax_name": "Mouse"
            },
            {
                "uniprot_canonical_ac": "O15392-1",
                "protein_name": "Baculoviral IAP repeat-containing protein 5",
                "gene_name": "BIRC5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5XUX0-1",
                "protein_name": "F-box only protein 31",
                "gene_name": "FBXO31",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15370-1",
                "protein_name": "Elongin-B",
                "gene_name": "ELOB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61077-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 D3",
                "gene_name": "UBE2D3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P51668-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 D1",
                "gene_name": "UBE2D1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O14508-1",
                "protein_name": "Suppressor of cytokine signaling 2",
                "gene_name": "SOCS2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q16531-1",
                "protein_name": "DNA damage-binding protein 1",
                "gene_name": "DDB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXI3-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 10",
                "gene_name": "ASB10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13200-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 2",
                "gene_name": "PSMD2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96GG9-1",
                "protein_name": "DCN1-like protein 1",
                "gene_name": "DCUN1D1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXK1-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 15",
                "gene_name": "ASB15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H765-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 8",
                "gene_name": "ASB8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y576-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 1",
                "gene_name": "ASB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96NS5-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 16",
                "gene_name": "ASB16",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXH4-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 11",
                "gene_name": "ASB11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXJ9-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 17",
                "gene_name": "ASB17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXK3-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 13",
                "gene_name": "ASB13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXK4-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 12",
                "gene_name": "ASB12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NWX5-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 6",
                "gene_name": "ASB6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y575-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 3",
                "gene_name": "ASB3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99814-1",
                "protein_name": "Endothelial PAS domain-containing protein 1",
                "gene_name": "EPAS1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BW61-1",
                "protein_name": "DET1- and DDB1-associated protein 1",
                "gene_name": "DDA1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N668-1",
                "protein_name": "COMM domain-containing protein 1",
                "gene_name": "COMMD1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62333-1",
                "protein_name": "26S proteasome regulatory subunit 10B",
                "gene_name": "PSMC6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WWX0-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 5",
                "gene_name": "ASB5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96DX5-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 9",
                "gene_name": "ASB9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UBI1-1",
                "protein_name": "COMM domain-containing protein 3",
                "gene_name": "COMMD3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61201-1",
                "protein_name": "COP9 signalosome complex subunit 2",
                "gene_name": "COPS2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7Z4G1-1",
                "protein_name": "COMM domain-containing protein 6",
                "gene_name": "COMMD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H0A8-1",
                "protein_name": "COMM domain-containing protein 4",
                "gene_name": "COMMD4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y6G5-1",
                "protein_name": "COMM domain-containing protein 10",
                "gene_name": "COMMD10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43242-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 3",
                "gene_name": "PSMD3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H0W5-1",
                "protein_name": "Coiled-coil domain-containing protein 8",
                "gene_name": "CCDC8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86X83-1",
                "protein_name": "COMM domain-containing protein 2",
                "gene_name": "COMMD2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86VX2-1",
                "protein_name": "COMM domain-containing protein 7",
                "gene_name": "COMMD7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9P000-1",
                "protein_name": "COMM domain-containing protein 9",
                "gene_name": "COMMD9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q969H0-1",
                "protein_name": "F-box/WD repeat-containing protein 7",
                "gene_name": "FBXW7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NX08-1",
                "protein_name": "COMM domain-containing protein 8",
                "gene_name": "COMMD8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9GZQ3-1",
                "protein_name": "COMM domain-containing protein 5",
                "gene_name": "COMMD5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5H9S7-1",
                "protein_name": "DDB1- and CUL4-associated factor 17",
                "gene_name": "DCAF17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61962-1",
                "protein_name": "DDB1- and CUL4-associated factor 7",
                "gene_name": "DCAF7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WV16-1",
                "protein_name": "DDB1- and CUL4-associated factor 4",
                "gene_name": "DCAF4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q53GT1-1",
                "protein_name": "Kelch-like protein 22",
                "gene_name": "KLHL22",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5QP82-1",
                "protein_name": "DDB1- and CUL4-associated factor 10",
                "gene_name": "DCAF10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O60662-1",
                "protein_name": "Kelch-like protein 41",
                "gene_name": "KLHL41",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9P2J3-1",
                "protein_name": "Kelch-like protein 9",
                "gene_name": "KLHL9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WWI1-1",
                "protein_name": "LIM domain only protein 7",
                "gene_name": "LMO7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NVR0-1",
                "protein_name": "Kelch-like protein 11",
                "gene_name": "KLHL11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9P2N7-1",
                "protein_name": "Kelch-like protein 13",
                "gene_name": "KLHL13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49721-1",
                "protein_name": "Proteasome subunit beta type-2",
                "gene_name": "PSMB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P20618-1",
                "protein_name": "Proteasome subunit beta type-1",
                "gene_name": "PSMB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15205-1",
                "protein_name": "Ubiquitin D",
                "gene_name": "UBD",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q16236-1",
                "protein_name": "Nuclear factor erythroid 2-related factor 2",
                "gene_name": "NFE2L2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96PQ7-1",
                "protein_name": "Kelch-like protein 5",
                "gene_name": "KLHL5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P15374-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase isozyme L3",
                "gene_name": "UCHL3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NYS7-1",
                "protein_name": "WD repeat and SOCS box-containing protein 2",
                "gene_name": "WSB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y6I7-1",
                "protein_name": "WD repeat and SOCS box-containing protein 1",
                "gene_name": "WSB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H9Q2-1",
                "protein_name": "COP9 signalosome complex subunit 7b",
                "gene_name": "COPS7B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92466-1",
                "protein_name": "DNA damage-binding protein 2",
                "gene_name": "DDB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q14999-1",
                "protein_name": "Cullin-7",
                "gene_name": "CUL7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O94888-1",
                "protein_name": "UBX domain-containing protein 7",
                "gene_name": "UBXN7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13098-4",
                "protein_name": "COP9 signalosome complex subunit 1",
                "gene_name": "GPS1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BT78-1",
                "protein_name": "COP9 signalosome complex subunit 4",
                "gene_name": "COPS4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62877-1",
                "protein_name": "E3 ubiquitin-protein ligase RBX1",
                "gene_name": "RBX1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15843-1",
                "protein_name": "Ubiquitin-like protein NEDD8",
                "gene_name": "NEDD8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61081-1",
                "protein_name": "NEDD8-conjugating enzyme Ubc12",
                "gene_name": "UBE2M",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28070-1",
                "protein_name": "Proteasome subunit beta type-4",
                "gene_name": "PSMB4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86V97-1",
                "protein_name": "Kelch repeat and BTB domain-containing protein 6",
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                "sequence_org": "ETGE",
                "sequence_mut": "",
                "comment": "Abolished interaction with KEAP1.",
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        "abstract": "",
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    {
        "title": "Crystal structure of a beta-catenin/APC complex reveals a critical role for APC phosphorylation in APC function.",
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        "authors": "Xing Y, Clements WK, Le Trong I, Hinds TR, Stenkamp R, Kimelman D, Xu W",
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    {
        "title": "TAB2 and TAB3 activate the NF-kappaB pathway through binding to polyubiquitin chains.",
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        "authors": "Kanayama A, Seth RB, Sun L, Ea CK, Hong M, Shaito A, Chiu YH, Deng L, Chen ZJ",
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            },
            {
                "uniprot_canonical_ac": "O95999-1",
                "protein_name": "B-cell lymphoma/leukemia 10",
                "gene_name": "BCL10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15111-1",
                "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit alpha",
                "gene_name": "CHUK",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15750-1",
                "protein_name": "TGF-beta-activated kinase 1 and MAP3K7-binding protein 1",
                "gene_name": "TAB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25963-1",
                "protein_name": "NF-kappa-B inhibitor alpha",
                "gene_name": "NFKBIA",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P55211-1",
                "protein_name": "Caspase-9",
                "gene_name": "CASP9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43187-1",
                "protein_name": "Interleukin-1 receptor-associated kinase-like 2",
                "gene_name": "IRAK2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y4K3-1",
                "protein_name": "TNF receptor-associated factor 6",
                "gene_name": "TRAF6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P21580-1",
                "protein_name": "Tumor necrosis factor alpha-induced protein 3",
                "gene_name": "TNFAIP3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P29466-1",
                "protein_name": "Caspase-1",
                "gene_name": "CASP1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13616-1",
                "protein_name": "Cullin-1",
                "gene_name": "CUL1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P43405-1",
                "protein_name": "Tyrosine-protein kinase SYK",
                "gene_name": "SYK",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P19838-1",
                "protein_name": "Nuclear factor NF-kappa-B p105 subunit",
                "gene_name": "NFKB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P52564-1",
                "protein_name": "Dual specificity mitogen-activated protein kinase kinase 6",
                "gene_name": "MAP2K6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62195-1",
                "protein_name": "26S proteasome regulatory subunit 8",
                "gene_name": "PSMC5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q01362-1",
                "protein_name": "High affinity immunoglobulin epsilon receptor subunit beta",
                "gene_name": "MS4A2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P30273-1",
                "protein_name": "High affinity immunoglobulin epsilon receptor subunit gamma",
                "gene_name": "FCER1G",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15264-1",
                "protein_name": "Mitogen-activated protein kinase 13",
                "gene_name": "MAPK13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25789-1",
                "protein_name": "Proteasome subunit alpha type-4",
                "gene_name": "PSMA4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7LDG7-1",
                "protein_name": "RAS guanyl-releasing protein 2",
                "gene_name": "RASGRP2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TDF6-1",
                "protein_name": "RAS guanyl-releasing protein 4",
                "gene_name": "RASGRP4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01767-1",
                "protein_name": "Immunoglobulin heavy variable 3-53",
                "gene_name": "IGHV3-53",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P06331-1",
                "protein_name": "Immunoglobulin heavy variable 4-34",
                "gene_name": "IGHV4-34",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01597-1",
                "protein_name": "Immunoglobulin kappa variable 1-39",
                "gene_name": "IGKV1-39",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P06310-1",
                "protein_name": "Immunoglobulin kappa variable 2-30",
                "gene_name": "IGKV2-30",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P06312-1",
                "protein_name": "Immunoglobulin kappa variable 4-1",
                "gene_name": "IGKV4-1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62191-1",
                "protein_name": "26S proteasome regulatory subunit 4",
                "gene_name": "PSMC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01614-1",
                "protein_name": "Immunoglobulin kappa variable 2D-40",
                "gene_name": "IGKV2D-40",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q05655-1",
                "protein_name": "Protein kinase C delta type",
                "gene_name": "PRKCD",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0DOY2-1",
                "protein_name": "Immunoglobulin lambda constant 2",
                "gene_name": "IGLC2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49720-1",
                "protein_name": "Proteasome subunit beta type-3",
                "gene_name": "PSMB3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99460-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 1",
                "gene_name": "PSMD1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UNM6-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 13",
                "gene_name": "PSMD13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P51665-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 7",
                "gene_name": "PSMD7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28074-1",
                "protein_name": "Proteasome subunit beta type-5",
                "gene_name": "PSMB5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P35998-1",
                "protein_name": "26S proteasome regulatory subunit 7",
                "gene_name": "PSMC2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P43686-1",
                "protein_name": "26S proteasome regulatory subunit 6B",
                "gene_name": "PSMC4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99436-1",
                "protein_name": "Proteasome subunit beta type-7",
                "gene_name": "PSMB7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O14920-1",
                "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit beta",
                "gene_name": "IKBKB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BXL7-1",
                "protein_name": "Caspase recruitment domain-containing protein 11",
                "gene_name": "CARD11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UDY8-1",
                "protein_name": "Mucosa-associated lymphoid tissue lymphoma translocation protein 1",
                "gene_name": "MALT1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P51668-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 D1",
                "gene_name": "UBE2D1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13200-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 2",
                "gene_name": "PSMD2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96J02-1",
                "protein_name": "E3 ubiquitin-protein ligase Itchy homolog",
                "gene_name": "ITCH",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62333-1",
                "protein_name": "26S proteasome regulatory subunit 10B",
                "gene_name": "PSMC6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P42575-1",
                "protein_name": "Caspase-2",
                "gene_name": "CASP2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49662-1",
                "protein_name": "Caspase-4",
                "gene_name": "CASP4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43242-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 3",
                "gene_name": "PSMD3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NQC7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase CYLD",
                "gene_name": "CYLD",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O00206-1",
                "protein_name": "Toll-like receptor 4",
                "gene_name": "TLR4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P04432-1",
                "protein_name": "Immunoglobulin kappa variable 1D-39",
                "gene_name": "IGKV1D-39",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P06315-1",
                "protein_name": "Immunoglobulin kappa variable 5-2",
                "gene_name": "IGKV5-2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01699-1",
                "protein_name": "Immunoglobulin lambda variable 1-44",
                "gene_name": "IGLV1-44",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01701-1",
                "protein_name": "Immunoglobulin lambda variable 1-51",
                "gene_name": "IGLV1-51",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01704-1",
                "protein_name": "Immunoglobulin lambda variable 2-14",
                "gene_name": "IGLV2-14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01706-1",
                "protein_name": "Immunoglobulin lambda variable 2-11",
                "gene_name": "IGLV2-11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01709-1",
                "protein_name": "Immunoglobulin lambda variable 2-8",
                "gene_name": "IGLV2-8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01717-1",
                "protein_name": "Immunoglobulin lambda variable 3-25",
                "gene_name": "IGLV3-25",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01721-1",
                "protein_name": "Immunoglobulin lambda variable 6-57",
                "gene_name": "IGLV6-57",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01703-1",
                "protein_name": "Immunoglobulin lambda variable 1-40",
                "gene_name": "IGLV1-40",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01705-1",
                "protein_name": "Immunoglobulin lambda variable 2-23",
                "gene_name": "IGLV2-23",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01715-1",
                "protein_name": "Immunoglobulin lambda variable 3-1",
                "gene_name": "IGLV3-1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01718-1",
                "protein_name": "Immunoglobulin lambda variable 3-27",
                "gene_name": "IGLV3-27",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P04211-1",
                "protein_name": "Immunoglobulin lambda variable 7-43",
                "gene_name": "IGLV7-43",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P53778-1",
                "protein_name": "Mitogen-activated protein kinase 12",
                "gene_name": "MAPK12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y6Y9-1",
                "protein_name": "Lymphocyte antigen 96",
                "gene_name": "LY96",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49721-1",
                "protein_name": "Proteasome subunit beta type-2",
                "gene_name": "PSMB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P20618-1",
                "protein_name": "Proteasome subunit beta type-1",
                "gene_name": "PSMB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43318-1",
                "protein_name": "Mitogen-activated protein kinase kinase kinase 7",
                "gene_name": "MAP3K7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49427-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 R1",
                "gene_name": "CDC34",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28070-1",
                "protein_name": "Proteasome subunit beta type-4",
                "gene_name": "PSMB4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0CF74-1",
                "protein_name": "Immunoglobulin lambda constant 6",
                "gene_name": "IGLC6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BXN2-1",
                "protein_name": "C-type lectin domain family 7 member A",
                "gene_name": "CLEC7A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H257-1",
                "protein_name": "Caspase recruitment domain-containing protein 9",
                "gene_name": "CARD9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9HC29-1",
                "protein_name": "Nucleotide-binding oligomerization domain-containing protein 2",
                "gene_name": "NOD2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25786-1",
                "protein_name": "Proteasome subunit alpha type-1",
                "gene_name": "PSMA1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96CG3-1",
                "protein_name": "TRAF-interacting protein with FHA domain-containing protein A",
                "gene_name": "TIFA",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P17980-1",
                "protein_name": "26S proteasome regulatory subunit 6A",
                "gene_name": "PSMC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y297-1",
                "protein_name": "F-box/WD repeat-containing protein 1A",
                "gene_name": "BTRC",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P07948-1",
                "protein_name": "Tyrosine-protein kinase Lyn",
                "gene_name": "LYN",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKB1-1",
                "protein_name": "F-box/WD repeat-containing protein 11",
                "gene_name": "FBXW11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P16885-1",
                "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2",
                "gene_name": "PLCG2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25788-1",
                "protein_name": "Proteasome subunit alpha type-3",
                "gene_name": "PSMA3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q14790-1",
                "protein_name": "Caspase-8",
                "gene_name": "CASP8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N5C8-1",
                "protein_name": "TGF-beta-activated kinase 1 and MAP3K7-binding protein 3",
                "gene_name": "TAB3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P60900-1",
                "protein_name": "Proteasome subunit alpha type-6",
                "gene_name": "PSMA6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13490-1",
                "protein_name": "Baculoviral IAP repeat-containing protein 2",
                "gene_name": "BIRC2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NYJ8-1",
                "protein_name": "TGF-beta-activated kinase 1 and MAP3K7-binding protein 2",
                "gene_name": "TAB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62979-1",
                "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein",
                "gene_name": "RPS27A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q04759-1",
                "protein_name": "Protein kinase C theta type",
                "gene_name": "PRKCQ",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43353-1",
                "protein_name": "Receptor-interacting serine/threonine-protein kinase 2",
                "gene_name": "RIPK2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61088-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 N",
                "gene_name": "UBE2N",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62837-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 D2",
                "gene_name": "UBE2D2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13489-1",
                "protein_name": "Baculoviral IAP repeat-containing protein 3",
                "gene_name": "BIRC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01825-1",
                "protein_name": "Immunoglobulin heavy variable 4-59",
                "gene_name": "IGHV4-59",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01817-1",
                "protein_name": "Immunoglobulin heavy variable 2-5",
                "gene_name": "IGHV2-5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01824-1",
                "protein_name": "Immunoglobulin heavy variable 4-39",
                "gene_name": "IGHV4-39",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P23083-1",
                "protein_name": "Immunoglobulin heavy variable 1-2",
                "gene_name": "IGHV1-2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15455-1",
                "protein_name": "Toll-like receptor 3",
                "gene_name": "TLR3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P48556-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 8",
                "gene_name": "PSMD8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15008-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 6",
                "gene_name": "PSMD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28072-1",
                "protein_name": "Proteasome subunit beta type-6",
                "gene_name": "PSMB6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O00232-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 12",
                "gene_name": "PSMD12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25787-1",
                "protein_name": "Proteasome subunit alpha type-2",
                "gene_name": "PSMA2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28066-1",
                "protein_name": "Proteasome subunit alpha type-5",
                "gene_name": "PSMA5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01742-1",
                "protein_name": "Immunoglobulin heavy variable 1-69",
                "gene_name": "IGHV1-69",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01768-1",
                "protein_name": "Immunoglobulin heavy variable 3-30",
                "gene_name": "IGHV3-30",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O95267-1",
                "protein_name": "RAS guanyl-releasing protein 1",
                "gene_name": "RASGRP1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01814-1",
                "protein_name": "Immunoglobulin heavy variable 2-70",
                "gene_name": "IGHV2-70",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01772-1",
                "protein_name": "Immunoglobulin heavy variable 3-33",
                "gene_name": "IGHV3-33",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01762-1",
                "protein_name": "Immunoglobulin heavy variable 3-11",
                "gene_name": "IGHV3-11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01763-1",
                "protein_name": "Immunoglobulin heavy variable 3-48",
                "gene_name": "IGHV3-48",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01764-1",
                "protein_name": "Immunoglobulin heavy variable 3-23",
                "gene_name": "IGHV3-23",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01766-1",
                "protein_name": "Immunoglobulin heavy variable 3-13",
                "gene_name": "IGHV3-13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01780-1",
                "protein_name": "Immunoglobulin heavy variable 3-7",
                "gene_name": "IGHV3-7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01782-1",
                "protein_name": "Immunoglobulin heavy variable 3-9",
                "gene_name": "IGHV3-9",
                "tax_name": "Human"
            },
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        "title": "A unique E1-E2 interaction required for optimal conjugation of the ubiquitin-like protein NEDD8.",
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                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NX08-1",
                "protein_name": "COMM domain-containing protein 8",
                "gene_name": "COMMD8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9GZQ3-1",
                "protein_name": "COMM domain-containing protein 5",
                "gene_name": "COMMD5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5H9S7-1",
                "protein_name": "DDB1- and CUL4-associated factor 17",
                "gene_name": "DCAF17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61962-1",
                "protein_name": "DDB1- and CUL4-associated factor 7",
                "gene_name": "DCAF7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WV16-1",
                "protein_name": "DDB1- and CUL4-associated factor 4",
                "gene_name": "DCAF4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q53GT1-1",
                "protein_name": "Kelch-like protein 22",
                "gene_name": "KLHL22",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5QP82-1",
                "protein_name": "DDB1- and CUL4-associated factor 10",
                "gene_name": "DCAF10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O60662-1",
                "protein_name": "Kelch-like protein 41",
                "gene_name": "KLHL41",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9P2J3-1",
                "protein_name": "Kelch-like protein 9",
                "gene_name": "KLHL9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WWI1-1",
                "protein_name": "LIM domain only protein 7",
                "gene_name": "LMO7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NVR0-1",
                "protein_name": "Kelch-like protein 11",
                "gene_name": "KLHL11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9P2N7-1",
                "protein_name": "Kelch-like protein 13",
                "gene_name": "KLHL13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49721-1",
                "protein_name": "Proteasome subunit beta type-2",
                "gene_name": "PSMB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P20618-1",
                "protein_name": "Proteasome subunit beta type-1",
                "gene_name": "PSMB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15205-1",
                "protein_name": "Ubiquitin D",
                "gene_name": "UBD",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q16236-1",
                "protein_name": "Nuclear factor erythroid 2-related factor 2",
                "gene_name": "NFE2L2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96PQ7-1",
                "protein_name": "Kelch-like protein 5",
                "gene_name": "KLHL5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P15374-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase isozyme L3",
                "gene_name": "UCHL3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NYS7-1",
                "protein_name": "WD repeat and SOCS box-containing protein 2",
                "gene_name": "WSB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y6I7-1",
                "protein_name": "WD repeat and SOCS box-containing protein 1",
                "gene_name": "WSB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H9Q2-1",
                "protein_name": "COP9 signalosome complex subunit 7b",
                "gene_name": "COPS7B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92466-1",
                "protein_name": "DNA damage-binding protein 2",
                "gene_name": "DDB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q14999-1",
                "protein_name": "Cullin-7",
                "gene_name": "CUL7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O94888-1",
                "protein_name": "UBX domain-containing protein 7",
                "gene_name": "UBXN7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13098-4",
                "protein_name": "COP9 signalosome complex subunit 1",
                "gene_name": "GPS1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BT78-1",
                "protein_name": "COP9 signalosome complex subunit 4",
                "gene_name": "COPS4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62877-1",
                "protein_name": "E3 ubiquitin-protein ligase RBX1",
                "gene_name": "RBX1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15843-1",
                "protein_name": "Ubiquitin-like protein NEDD8",
                "gene_name": "NEDD8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61081-1",
                "protein_name": "NEDD8-conjugating enzyme Ubc12",
                "gene_name": "UBE2M",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28070-1",
                "protein_name": "Proteasome subunit beta type-4",
                "gene_name": "PSMB4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86V97-1",
                "protein_name": "Kelch repeat and BTB domain-containing protein 6",
                "gene_name": "KBTBD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WVZ9-1",
                "protein_name": "Kelch repeat and BTB domain-containing protein 7",
                "gene_name": "KBTBD7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NRJ4-1",
                "protein_name": "Tubby-related protein 4",
                "gene_name": "TULP4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61964-1",
                "protein_name": "WD repeat-containing protein 5",
                "gene_name": "WDR5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P55072-1",
                "protein_name": "Transitional endoplasmic reticulum ATPase",
                "gene_name": "VCP",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13618-1",
                "protein_name": "Cullin-3",
                "gene_name": "CUL3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25786-1",
                "protein_name": "Proteasome subunit alpha type-1",
                "gene_name": "PSMA1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NHY2-1",
                "protein_name": "E3 ubiquitin-protein ligase COP1",
                "gene_name": "COP1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7L5N1-1",
                "protein_name": "COP9 signalosome complex subunit 6",
                "gene_name": "COPS6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P40337-1",
                "protein_name": "von Hippel-Lindau disease tumor suppressor",
                "gene_name": "VHL",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5TAQ9-1",
                "protein_name": "DDB1- and CUL4-associated factor 8",
                "gene_name": "DCAF8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96BD6-1",
                "protein_name": "SPRY domain-containing SOCS box protein 1",
                "gene_name": "SPSB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5JTC6-1",
                "protein_name": "APC membrane recruitment protein 1",
                "gene_name": "AMER1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P17980-1",
                "protein_name": "26S proteasome regulatory subunit 6A",
                "gene_name": "PSMC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99619-1",
                "protein_name": "SPRY domain-containing SOCS box protein 2",
                "gene_name": "SPSB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O60826-1",
                "protein_name": "Coiled-coil domain-containing protein 22",
                "gene_name": "CCDC22",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NC69-1",
                "protein_name": "BTB/POZ domain-containing protein KCTD6",
                "gene_name": "KCTD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y297-1",
                "protein_name": "F-box/WD repeat-containing protein 1A",
                "gene_name": "BTRC",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O14544-1",
                "protein_name": "Suppressor of cytokine signaling 6",
                "gene_name": "SOCS6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKB1-1",
                "protein_name": "F-box/WD repeat-containing protein 11",
                "gene_name": "FBXW11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25788-1",
                "protein_name": "Proteasome subunit alpha type-3",
                "gene_name": "PSMA3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8IWE4-1",
                "protein_name": "DCN1-like protein 3",
                "gene_name": "DCUN1D3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UH77-1",
                "protein_name": "Kelch-like protein 3",
                "gene_name": "KLHL3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q969P5-1",
                "protein_name": "F-box only protein 32",
                "gene_name": "FBXO32",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y3I1-1",
                "protein_name": "F-box only protein 7",
                "gene_name": "FBXO7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H469-1",
                "protein_name": "F-box/LRR-repeat protein 15",
                "gene_name": "FBXL15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96CD0-1",
                "protein_name": "F-box/LRR-repeat protein 8",
                "gene_name": "FBXL8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NEE6-1",
                "protein_name": "F-box and leucine-rich repeat protein 13",
                "gene_name": "FBXL13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKT7-1",
                "protein_name": "F-box/LRR-repeat protein 3",
                "gene_name": "FBXL3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96EF6-1",
                "protein_name": "F-box only protein 17",
                "gene_name": "FBXO17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UK22-1",
                "protein_name": "F-box only protein 2",
                "gene_name": "FBXO2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P57775-1",
                "protein_name": "F-box/WD repeat-containing protein 4",
                "gene_name": "FBXW4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N1E6-1",
                "protein_name": "F-box/LRR-repeat protein 14",
                "gene_name": "FBXL14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96ME1-4",
                "protein_name": "F-box/LRR-repeat protein 18",
                "gene_name": "FBXL18",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UJT9-1",
                "protein_name": "F-box/LRR-repeat protein 7",
                "gene_name": "FBXL7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKT6-1",
                "protein_name": "Putative F-box/LRR-repeat protein 21",
                "gene_name": "FBXL21P",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O14543-1",
                "protein_name": "Suppressor of cytokine signaling 3",
                "gene_name": "SOCS3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N5D0-1",
                "protein_name": "WD and tetratricopeptide repeats protein 1",
                "gene_name": "WDTC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13501-1",
                "protein_name": "Sequestosome-1",
                "gene_name": "SQSTM1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q969U6-1",
                "protein_name": "F-box/WD repeat-containing protein 5",
                "gene_name": "FBXW5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86XK2-1",
                "protein_name": "F-box only protein 11",
                "gene_name": "FBXO11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P60900-1",
                "protein_name": "Proteasome subunit alpha type-6",
                "gene_name": "PSMA6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62979-1",
                "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein",
                "gene_name": "RPS27A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86YC2-1",
                "protein_name": "Partner and localizer of BRCA2",
                "gene_name": "PALB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H4M3-1",
                "protein_name": "F-box only protein 44",
                "gene_name": "FBXO44",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96KE9-3",
                "protein_name": "BTB/POZ domain-containing protein 6",
                "gene_name": "BTBD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92905-1",
                "protein_name": "COP9 signalosome complex subunit 5",
                "gene_name": "COPS5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13617-1",
                "protein_name": "Cullin-2",
                "gene_name": "CUL2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13619-1",
                "protein_name": "Cullin-4A",
                "gene_name": "CUL4A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86VP6-1",
                "protein_name": "Cullin-associated NEDD8-dissociated protein 1",
                "gene_name": "CAND1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62837-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 D2",
                "gene_name": "UBE2D2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13620-2",
                "protein_name": "Cullin-4B",
                "gene_name": "CUL4B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H0C5-1",
                "protein_name": "BTB/POZ domain-containing protein 1",
                "gene_name": "BTBD1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NXF7-1",
                "protein_name": "DDB1- and CUL4-associated factor 16",
                "gene_name": "DCAF16",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y2N7-1",
                "protein_name": "Hypoxia-inducible factor 3-alpha",
                "gene_name": "HIF3A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P48556-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 8",
                "gene_name": "PSMD8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15008-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 6",
                "gene_name": "PSMD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28072-1",
                "protein_name": "Proteasome subunit beta type-6",
                "gene_name": "PSMB6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O00232-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 12",
                "gene_name": "PSMD12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25787-1",
                "protein_name": "Proteasome subunit alpha type-2",
                "gene_name": "PSMA2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28066-1",
                "protein_name": "Proteasome subunit alpha type-5",
                "gene_name": "PSMA5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NCQ5-1",
                "protein_name": "F-box only protein 15",
                "gene_name": "FBXO15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UK96-1",
                "protein_name": "F-box only protein 10",
                "gene_name": "FBXO10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TB52-1",
                "protein_name": "F-box only protein 30",
                "gene_name": "FBXO30",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96JP0-1",
                "protein_name": "Protein fem-1 homolog C",
                "gene_name": "FEM1C",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UH90-1",
                "protein_name": "F-box only protein 40",
                "gene_name": "FBXO40",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q969M7-1",
                "protein_name": "NEDD8-conjugating enzyme UBE2F",
                "gene_name": "UBE2F-SCLY; UBE2F",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96LD8-1",
                "protein_name": "Sentrin-specific protease 8",
                "gene_name": "SENP8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13564-1",
                "protein_name": "NEDD8-activating enzyme E1 regulatory subunit",
                "gene_name": "NAE1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O95198-1",
                "protein_name": "Kelch-like protein 2",
                "gene_name": "KLHL2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P38936-1",
                "protein_name": "Cyclin-dependent kinase inhibitor 1",
                "gene_name": "CDKN1A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NXK8-1",
                "protein_name": "F-box/LRR-repeat protein 12",
                "gene_name": "FBXL12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0CG47-1",
                "protein_name": "Polyubiquitin-B",
                "gene_name": "UBB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKT8-1",
                "protein_name": "F-box/WD repeat-containing protein 2",
                "gene_name": "FBXW2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TEB1-1",
                "protein_name": "DDB1- and CUL4-associated factor 11",
                "gene_name": "DCAF11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TB72-1",
                "protein_name": "Pumilio homolog 2",
                "gene_name": "PUM2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BTE7-1",
                "protein_name": "DCN1-like protein 5",
                "gene_name": "DCUN1D5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q58WW2-1",
                "protein_name": "DDB1- and CUL4-associated factor 6",
                "gene_name": "DCAF6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6PH85-1",
                "protein_name": "DCN1-like protein 2",
                "gene_name": "DCUN1D2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92564-1",
                "protein_name": "DCN1-like protein 4",
                "gene_name": "DCUN1D4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96JK2-1",
                "protein_name": "DDB1- and CUL4-associated factor 5",
                "gene_name": "DCAF5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62987-1",
                "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein",
                "gene_name": "UBA52",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NZJ0-1",
                "protein_name": "Denticleless protein homolog",
                "gene_name": "DTL",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NV06-1",
                "protein_name": "DDB1- and CUL4-associated factor 13",
                "gene_name": "DCAF13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NY33-1",
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    {
        "title": "The Keap1-BTB protein is an adaptor that bridges Nrf2 to a Cul3-based E3 ligase: oxidative stress sensing by a Cul3-Keap1 ligase.",
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                "uniprot_canonical_ac": "Q15291-1",
                "protein_name": "Retinoblastoma-binding protein 5",
                "gene_name": "RBBP5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6ZVZ8-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 18",
                "gene_name": "ASB18",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TAT6-1",
                "protein_name": "Nuclear protein localization protein 4 homolog",
                "gene_name": "NPLOC4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92890-2",
                "protein_name": "Ubiquitin recognition factor in ER-associated degradation protein 1",
                "gene_name": "UFD1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P41002-1",
                "protein_name": "Cyclin-F",
                "gene_name": "CCNF",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q05516-1",
                "protein_name": "Zinc finger and BTB domain-containing protein 16",
                "gene_name": "ZBTB16",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15369-1",
                "protein_name": "Elongin-C",
                "gene_name": "ELOC",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8IWT3-1",
                "protein_name": "Cullin-9",
                "gene_name": "CUL9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TBC4-1",
                "protein_name": "NEDD8-activating enzyme E1 catalytic subunit",
                "gene_name": "UBA3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13216-1",
                "protein_name": "DNA excision repair protein ERCC-8",
                "gene_name": "ERCC8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62195-1",
                "protein_name": "26S proteasome regulatory subunit 8",
                "gene_name": "PSMC5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q16576-1",
                "protein_name": "Histone-binding protein RBBP7",
                "gene_name": "RBBP7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NI29-1",
                "protein_name": "F-box only protein 27",
                "gene_name": "FBXO27",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6P050-1",
                "protein_name": "F-box and leucine-rich protein 22",
                "gene_name": "FBXL22",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NEZ5-1",
                "protein_name": "F-box only protein 22",
                "gene_name": "FBXO22",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NRD1-1",
                "protein_name": "F-box only protein 6",
                "gene_name": "FBXO6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5XUX1-3",
                "protein_name": "F-box/WD repeat-containing protein 9",
                "gene_name": "FBXW9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N3Y1-1",
                "protein_name": "F-box/WD repeat-containing protein 8",
                "gene_name": "FBXW8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UK97-1",
                "protein_name": "F-box only protein 9",
                "gene_name": "FBXO9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKA1-1",
                "protein_name": "F-box/LRR-repeat protein 5",
                "gene_name": "FBXL5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKA2-1",
                "protein_name": "F-box/LRR-repeat protein 4",
                "gene_name": "FBXL4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6PCT2-1",
                "protein_name": "F-box/LRR-repeat protein 19",
                "gene_name": "FBXL19",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N461-1",
                "protein_name": "F-box/LRR-repeat protein 16",
                "gene_name": "FBXL16",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25789-1",
                "protein_name": "Proteasome subunit alpha type-4",
                "gene_name": "PSMA4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H2C0-1",
                "protein_name": "Gigaxonin",
                "gene_name": "GAN",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15345-2",
                "protein_name": "Leucine-rich repeat-containing protein 41",
                "gene_name": "LRRC41",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96MP8-1",
                "protein_name": "BTB/POZ domain-containing protein KCTD7",
                "gene_name": "KCTD7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9JR72-1",
                "protein_name": "Kelch repeat and BTB domain-containing protein 13",
                "gene_name": "KBTBD13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H0H3-1",
                "protein_name": "Kelch-like protein 25",
                "gene_name": "KLHL25",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UJP4-1",
                "protein_name": "Kelch-like protein 21",
                "gene_name": "KLHL21",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96L50-1",
                "protein_name": "Leucine-rich repeat protein 1",
                "gene_name": "LRR1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62191-1",
                "protein_name": "26S proteasome regulatory subunit 4",
                "gene_name": "PSMC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UBW8-1",
                "protein_name": "COP9 signalosome complex subunit 7a",
                "gene_name": "COPS7A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99627-1",
                "protein_name": "COP9 signalosome complex subunit 8",
                "gene_name": "COPS8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O75147-3",
                "protein_name": "Obscurin-like protein 1",
                "gene_name": "OBSL1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49720-1",
                "protein_name": "Proteasome subunit beta type-3",
                "gene_name": "PSMB3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99460-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 1",
                "gene_name": "PSMD1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UNM6-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 13",
                "gene_name": "PSMD13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P51665-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 7",
                "gene_name": "PSMD7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NSE2-1",
                "protein_name": "Cytokine-inducible SH2-containing protein",
                "gene_name": "CISH",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13309-1",
                "protein_name": "S-phase kinase-associated protein 2",
                "gene_name": "SKP2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q60795-1",
                "protein_name": "Nuclear factor erythroid 2-related factor 2",
                "gene_name": "Nfe2l2",
                "tax_name": "Mouse"
            },
            {
                "uniprot_canonical_ac": "Q9Z2X8-1",
                "protein_name": "Kelch-like ECH-associated protein 1",
                "gene_name": "Keap1",
                "tax_name": "Mouse"
            },
            {
                "uniprot_canonical_ac": "Q9BR09-1",
                "protein_name": "Neuralized-like protein 2",
                "gene_name": "NEURL2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28074-1",
                "protein_name": "Proteasome subunit beta type-5",
                "gene_name": "PSMB5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P35998-1",
                "protein_name": "26S proteasome regulatory subunit 7",
                "gene_name": "PSMC2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P43686-1",
                "protein_name": "26S proteasome regulatory subunit 6B",
                "gene_name": "PSMC4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99436-1",
                "protein_name": "Proteasome subunit beta type-7",
                "gene_name": "PSMB7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15392-1",
                "protein_name": "Baculoviral IAP repeat-containing protein 5",
                "gene_name": "BIRC5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5XUX0-1",
                "protein_name": "F-box only protein 31",
                "gene_name": "FBXO31",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15370-1",
                "protein_name": "Elongin-B",
                "gene_name": "ELOB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61077-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 D3",
                "gene_name": "UBE2D3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P51668-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 D1",
                "gene_name": "UBE2D1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O14508-1",
                "protein_name": "Suppressor of cytokine signaling 2",
                "gene_name": "SOCS2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q16531-1",
                "protein_name": "DNA damage-binding protein 1",
                "gene_name": "DDB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXI3-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 10",
                "gene_name": "ASB10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13200-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 2",
                "gene_name": "PSMD2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96GG9-1",
                "protein_name": "DCN1-like protein 1",
                "gene_name": "DCUN1D1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXK1-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 15",
                "gene_name": "ASB15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H765-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 8",
                "gene_name": "ASB8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y576-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 1",
                "gene_name": "ASB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96NS5-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 16",
                "gene_name": "ASB16",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXH4-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 11",
                "gene_name": "ASB11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXJ9-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 17",
                "gene_name": "ASB17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXK3-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 13",
                "gene_name": "ASB13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXK4-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 12",
                "gene_name": "ASB12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NWX5-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 6",
                "gene_name": "ASB6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y575-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 3",
                "gene_name": "ASB3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99814-1",
                "protein_name": "Endothelial PAS domain-containing protein 1",
                "gene_name": "EPAS1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BW61-1",
                "protein_name": "DET1- and DDB1-associated protein 1",
                "gene_name": "DDA1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N668-1",
                "protein_name": "COMM domain-containing protein 1",
                "gene_name": "COMMD1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62333-1",
                "protein_name": "26S proteasome regulatory subunit 10B",
                "gene_name": "PSMC6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WWX0-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 5",
                "gene_name": "ASB5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96DX5-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 9",
                "gene_name": "ASB9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UBI1-1",
                "protein_name": "COMM domain-containing protein 3",
                "gene_name": "COMMD3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61201-1",
                "protein_name": "COP9 signalosome complex subunit 2",
                "gene_name": "COPS2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7Z4G1-1",
                "protein_name": "COMM domain-containing protein 6",
                "gene_name": "COMMD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H0A8-1",
                "protein_name": "COMM domain-containing protein 4",
                "gene_name": "COMMD4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y6G5-1",
                "protein_name": "COMM domain-containing protein 10",
                "gene_name": "COMMD10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43242-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 3",
                "gene_name": "PSMD3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H0W5-1",
                "protein_name": "Coiled-coil domain-containing protein 8",
                "gene_name": "CCDC8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86X83-1",
                "protein_name": "COMM domain-containing protein 2",
                "gene_name": "COMMD2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86VX2-1",
                "protein_name": "COMM domain-containing protein 7",
                "gene_name": "COMMD7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9P000-1",
                "protein_name": "COMM domain-containing protein 9",
                "gene_name": "COMMD9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q969H0-1",
                "protein_name": "F-box/WD repeat-containing protein 7",
                "gene_name": "FBXW7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NX08-1",
                "protein_name": "COMM domain-containing protein 8",
                "gene_name": "COMMD8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9GZQ3-1",
                "protein_name": "COMM domain-containing protein 5",
                "gene_name": "COMMD5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5H9S7-1",
                "protein_name": "DDB1- and CUL4-associated factor 17",
                "gene_name": "DCAF17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61962-1",
                "protein_name": "DDB1- and CUL4-associated factor 7",
                "gene_name": "DCAF7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WV16-1",
                "protein_name": "DDB1- and CUL4-associated factor 4",
                "gene_name": "DCAF4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q53GT1-1",
                "protein_name": "Kelch-like protein 22",
                "gene_name": "KLHL22",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5QP82-1",
                "protein_name": "DDB1- and CUL4-associated factor 10",
                "gene_name": "DCAF10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O60662-1",
                "protein_name": "Kelch-like protein 41",
                "gene_name": "KLHL41",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9P2J3-1",
                "protein_name": "Kelch-like protein 9",
                "gene_name": "KLHL9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WWI1-1",
                "protein_name": "LIM domain only protein 7",
                "gene_name": "LMO7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NVR0-1",
                "protein_name": "Kelch-like protein 11",
                "gene_name": "KLHL11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9P2N7-1",
                "protein_name": "Kelch-like protein 13",
                "gene_name": "KLHL13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49721-1",
                "protein_name": "Proteasome subunit beta type-2",
                "gene_name": "PSMB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P20618-1",
                "protein_name": "Proteasome subunit beta type-1",
                "gene_name": "PSMB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15205-1",
                "protein_name": "Ubiquitin D",
                "gene_name": "UBD",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q16236-1",
                "protein_name": "Nuclear factor erythroid 2-related factor 2",
                "gene_name": "NFE2L2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96PQ7-1",
                "protein_name": "Kelch-like protein 5",
                "gene_name": "KLHL5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P15374-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase isozyme L3",
                "gene_name": "UCHL3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NYS7-1",
                "protein_name": "WD repeat and SOCS box-containing protein 2",
                "gene_name": "WSB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y6I7-1",
                "protein_name": "WD repeat and SOCS box-containing protein 1",
                "gene_name": "WSB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H9Q2-1",
                "protein_name": "COP9 signalosome complex subunit 7b",
                "gene_name": "COPS7B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92466-1",
                "protein_name": "DNA damage-binding protein 2",
                "gene_name": "DDB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q14999-1",
                "protein_name": "Cullin-7",
                "gene_name": "CUL7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O94888-1",
                "protein_name": "UBX domain-containing protein 7",
                "gene_name": "UBXN7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13098-4",
                "protein_name": "COP9 signalosome complex subunit 1",
                "gene_name": "GPS1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BT78-1",
                "protein_name": "COP9 signalosome complex subunit 4",
                "gene_name": "COPS4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62877-1",
                "protein_name": "E3 ubiquitin-protein ligase RBX1",
                "gene_name": "RBX1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15843-1",
                "protein_name": "Ubiquitin-like protein NEDD8",
                "gene_name": "NEDD8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61081-1",
                "protein_name": "NEDD8-conjugating enzyme Ubc12",
                "gene_name": "UBE2M",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28070-1",
                "protein_name": "Proteasome subunit beta type-4",
                "gene_name": "PSMB4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86V97-1",
                "protein_name": "Kelch repeat and BTB domain-containing protein 6",
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                "glygen_name": "Human",
                "reference_species": "Homo sapiens [9606]"
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        ],
        "record_id": "pubmed.15367669",
        "abstract": "",
        "glycosylation": [],
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    {
        "title": "Signaling to NF-kappaB.",
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    {
        "title": "Plk1 regulates activation of the anaphase promoting complex by phosphorylating and triggering SCFbetaTrCP-dependent destruction of the APC Inhibitor Emi1.",
        "journal": "Molecular biology of the cell",
        "date": "2004",
        "authors": "Hansen DV, Loktev AV, Ban KH, Jackson PK",
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            "id": "15469984",
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                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "P25789-1",
                "protein_name": "Proteasome subunit alpha type-4",
                "gene_name": "PSMA4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62191-1",
                "protein_name": "26S proteasome regulatory subunit 4",
                "gene_name": "PSMC1",
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            {
                "uniprot_canonical_ac": "P49720-1",
                "protein_name": "Proteasome subunit beta type-3",
                "gene_name": "PSMB3",
                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "Q99460-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 1",
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                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UNM6-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 13",
                "gene_name": "PSMD13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P51665-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 7",
                "gene_name": "PSMD7",
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                "protein_name": "Proteasome subunit beta type-5",
                "gene_name": "PSMB5",
                "tax_name": "Human"
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                "tax_name": "Human"
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            {
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                "protein_name": "26S proteasome regulatory subunit 6B",
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            {
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                "uniprot_canonical_ac": "P53350-1",
                "protein_name": "Serine/threonine-protein kinase PLK1",
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                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "O00487-1",
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                "protein_name": "F-box/LRR-repeat protein 5",
                "gene_name": "FBXL5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKA2-1",
                "protein_name": "F-box/LRR-repeat protein 4",
                "gene_name": "FBXL4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6PCT2-1",
                "protein_name": "F-box/LRR-repeat protein 19",
                "gene_name": "FBXL19",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N461-1",
                "protein_name": "F-box/LRR-repeat protein 16",
                "gene_name": "FBXL16",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25789-1",
                "protein_name": "Proteasome subunit alpha type-4",
                "gene_name": "PSMA4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H2C0-1",
                "protein_name": "Gigaxonin",
                "gene_name": "GAN",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P09601-1",
                "protein_name": "Heme oxygenase 1",
                "gene_name": "HMOX1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15345-2",
                "protein_name": "Leucine-rich repeat-containing protein 41",
                "gene_name": "LRRC41",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96MP8-1",
                "protein_name": "BTB/POZ domain-containing protein KCTD7",
                "gene_name": "KCTD7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9JR72-1",
                "protein_name": "Kelch repeat and BTB domain-containing protein 13",
                "gene_name": "KBTBD13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H0H3-1",
                "protein_name": "Kelch-like protein 25",
                "gene_name": "KLHL25",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UJP4-1",
                "protein_name": "Kelch-like protein 21",
                "gene_name": "KLHL21",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96L50-1",
                "protein_name": "Leucine-rich repeat protein 1",
                "gene_name": "LRR1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62191-1",
                "protein_name": "26S proteasome regulatory subunit 4",
                "gene_name": "PSMC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UBW8-1",
                "protein_name": "COP9 signalosome complex subunit 7a",
                "gene_name": "COPS7A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99627-1",
                "protein_name": "COP9 signalosome complex subunit 8",
                "gene_name": "COPS8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O75147-3",
                "protein_name": "Obscurin-like protein 1",
                "gene_name": "OBSL1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96NT5-1",
                "protein_name": "Proton-coupled folate transporter",
                "gene_name": "SLC46A1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49720-1",
                "protein_name": "Proteasome subunit beta type-3",
                "gene_name": "PSMB3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99460-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 1",
                "gene_name": "PSMD1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UNM6-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 13",
                "gene_name": "PSMD13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P51665-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 7",
                "gene_name": "PSMD7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NSE2-1",
                "protein_name": "Cytokine-inducible SH2-containing protein",
                "gene_name": "CISH",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13309-1",
                "protein_name": "S-phase kinase-associated protein 2",
                "gene_name": "SKP2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BR09-1",
                "protein_name": "Neuralized-like protein 2",
                "gene_name": "NEURL2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28074-1",
                "protein_name": "Proteasome subunit beta type-5",
                "gene_name": "PSMB5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P35998-1",
                "protein_name": "26S proteasome regulatory subunit 7",
                "gene_name": "PSMC2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P43686-1",
                "protein_name": "26S proteasome regulatory subunit 6B",
                "gene_name": "PSMC4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99436-1",
                "protein_name": "Proteasome subunit beta type-7",
                "gene_name": "PSMB7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WUG5-1",
                "protein_name": "Solute carrier family 22 member 17",
                "gene_name": "SLC22A17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15392-1",
                "protein_name": "Baculoviral IAP repeat-containing protein 5",
                "gene_name": "BIRC5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5XUX0-1",
                "protein_name": "F-box only protein 31",
                "gene_name": "FBXO31",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15370-1",
                "protein_name": "Elongin-B",
                "gene_name": "ELOB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61077-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 D3",
                "gene_name": "UBE2D3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P51668-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 D1",
                "gene_name": "UBE2D1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O14508-1",
                "protein_name": "Suppressor of cytokine signaling 2",
                "gene_name": "SOCS2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q16531-1",
                "protein_name": "DNA damage-binding protein 1",
                "gene_name": "DDB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXI3-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 10",
                "gene_name": "ASB10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13200-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 2",
                "gene_name": "PSMD2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96GG9-1",
                "protein_name": "DCN1-like protein 1",
                "gene_name": "DCUN1D1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXK1-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 15",
                "gene_name": "ASB15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H765-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 8",
                "gene_name": "ASB8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y576-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 1",
                "gene_name": "ASB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96NS5-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 16",
                "gene_name": "ASB16",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXH4-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 11",
                "gene_name": "ASB11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXJ9-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 17",
                "gene_name": "ASB17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXK3-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 13",
                "gene_name": "ASB13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXK4-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 12",
                "gene_name": "ASB12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NWX5-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 6",
                "gene_name": "ASB6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y575-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 3",
                "gene_name": "ASB3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99814-1",
                "protein_name": "Endothelial PAS domain-containing protein 1",
                "gene_name": "EPAS1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BW61-1",
                "protein_name": "DET1- and DDB1-associated protein 1",
                "gene_name": "DDA1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N668-1",
                "protein_name": "COMM domain-containing protein 1",
                "gene_name": "COMMD1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62333-1",
                "protein_name": "26S proteasome regulatory subunit 10B",
                "gene_name": "PSMC6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WWX0-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 5",
                "gene_name": "ASB5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96DX5-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 9",
                "gene_name": "ASB9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UBI1-1",
                "protein_name": "COMM domain-containing protein 3",
                "gene_name": "COMMD3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61201-1",
                "protein_name": "COP9 signalosome complex subunit 2",
                "gene_name": "COPS2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7Z4G1-1",
                "protein_name": "COMM domain-containing protein 6",
                "gene_name": "COMMD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H0A8-1",
                "protein_name": "COMM domain-containing protein 4",
                "gene_name": "COMMD4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y6G5-1",
                "protein_name": "COMM domain-containing protein 10",
                "gene_name": "COMMD10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43242-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 3",
                "gene_name": "PSMD3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H0W5-1",
                "protein_name": "Coiled-coil domain-containing protein 8",
                "gene_name": "CCDC8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P00450-1",
                "protein_name": "Ceruloplasmin",
                "gene_name": "CP",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86X83-1",
                "protein_name": "COMM domain-containing protein 2",
                "gene_name": "COMMD2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86VX2-1",
                "protein_name": "COMM domain-containing protein 7",
                "gene_name": "COMMD7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9P000-1",
                "protein_name": "COMM domain-containing protein 9",
                "gene_name": "COMMD9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q969H0-1",
                "protein_name": "F-box/WD repeat-containing protein 7",
                "gene_name": "FBXW7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NX08-1",
                "protein_name": "COMM domain-containing protein 8",
                "gene_name": "COMMD8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9GZQ3-1",
                "protein_name": "COMM domain-containing protein 5",
                "gene_name": "COMMD5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5H9S7-1",
                "protein_name": "DDB1- and CUL4-associated factor 17",
                "gene_name": "DCAF17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61962-1",
                "protein_name": "DDB1- and CUL4-associated factor 7",
                "gene_name": "DCAF7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WV16-1",
                "protein_name": "DDB1- and CUL4-associated factor 4",
                "gene_name": "DCAF4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q53GT1-1",
                "protein_name": "Kelch-like protein 22",
                "gene_name": "KLHL22",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5QP82-1",
                "protein_name": "DDB1- and CUL4-associated factor 10",
                "gene_name": "DCAF10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O60662-1",
                "protein_name": "Kelch-like protein 41",
                "gene_name": "KLHL41",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9P2J3-1",
                "protein_name": "Kelch-like protein 9",
                "gene_name": "KLHL9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WWI1-1",
                "protein_name": "LIM domain only protein 7",
                "gene_name": "LMO7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P48200-1",
                "protein_name": "Iron-responsive element-binding protein 2",
                "gene_name": "IREB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NVR0-1",
                "protein_name": "Kelch-like protein 11",
                "gene_name": "KLHL11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9P2N7-1",
                "protein_name": "Kelch-like protein 13",
                "gene_name": "KLHL13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49721-1",
                "protein_name": "Proteasome subunit beta type-2",
                "gene_name": "PSMB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P20618-1",
                "protein_name": "Proteasome subunit beta type-1",
                "gene_name": "PSMB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15205-1",
                "protein_name": "Ubiquitin D",
                "gene_name": "UBD",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q16236-1",
                "protein_name": "Nuclear factor erythroid 2-related factor 2",
                "gene_name": "NFE2L2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96PQ7-1",
                "protein_name": "Kelch-like protein 5",
                "gene_name": "KLHL5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P15374-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase isozyme L3",
                "gene_name": "UCHL3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NYS7-1",
                "protein_name": "WD repeat and SOCS box-containing protein 2",
                "gene_name": "WSB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y6I7-1",
                "protein_name": "WD repeat and SOCS box-containing protein 1",
                "gene_name": "WSB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H9Q2-1",
                "protein_name": "COP9 signalosome complex subunit 7b",
                "gene_name": "COPS7B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92466-1",
                "protein_name": "DNA damage-binding protein 2",
                "gene_name": "DDB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q14999-1",
                "protein_name": "Cullin-7",
                "gene_name": "CUL7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O94888-1",
                "protein_name": "UBX domain-containing protein 7",
                "gene_name": "UBXN7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13098-4",
                "protein_name": "COP9 signalosome complex subunit 1",
                "gene_name": "GPS1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BT78-1",
                "protein_name": "COP9 signalosome complex subunit 4",
                "gene_name": "COPS4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62877-1",
                "protein_name": "E3 ubiquitin-protein ligase RBX1",
                "gene_name": "RBX1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15843-1",
                "protein_name": "Ubiquitin-like protein NEDD8",
                "gene_name": "NEDD8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61081-1",
                "protein_name": "NEDD8-conjugating enzyme Ubc12",
                "gene_name": "UBE2M",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28070-1",
                "protein_name": "Proteasome subunit beta type-4",
                "gene_name": "PSMB4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86V97-1",
                "protein_name": "Kelch repeat and BTB domain-containing protein 6",
                "gene_name": "KBTBD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WVZ9-1",
                "protein_name": "Kelch repeat and BTB domain-containing protein 7",
                "gene_name": "KBTBD7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NRJ4-1",
                "protein_name": "Tubby-related protein 4",
                "gene_name": "TULP4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61964-1",
                "protein_name": "WD repeat-containing protein 5",
                "gene_name": "WDR5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P21399-1",
                "protein_name": "Cytoplasmic aconitate hydratase",
                "gene_name": "ACO1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P55072-1",
                "protein_name": "Transitional endoplasmic reticulum ATPase",
                "gene_name": "VCP",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13618-1",
                "protein_name": "Cullin-3",
                "gene_name": "CUL3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25786-1",
                "protein_name": "Proteasome subunit alpha type-1",
                "gene_name": "PSMA1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NHY2-1",
                "protein_name": "E3 ubiquitin-protein ligase COP1",
                "gene_name": "COP1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7L5N1-1",
                "protein_name": "COP9 signalosome complex subunit 6",
                "gene_name": "COPS6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P40337-1",
                "protein_name": "von Hippel-Lindau disease tumor suppressor",
                "gene_name": "VHL",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5TAQ9-1",
                "protein_name": "DDB1- and CUL4-associated factor 8",
                "gene_name": "DCAF8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96BD6-1",
                "protein_name": "SPRY domain-containing SOCS box protein 1",
                "gene_name": "SPSB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5JTC6-1",
                "protein_name": "APC membrane recruitment protein 1",
                "gene_name": "AMER1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P17980-1",
                "protein_name": "26S proteasome regulatory subunit 6A",
                "gene_name": "PSMC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99619-1",
                "protein_name": "SPRY domain-containing SOCS box protein 2",
                "gene_name": "SPSB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O60826-1",
                "protein_name": "Coiled-coil domain-containing protein 22",
                "gene_name": "CCDC22",
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        ],
        "record_id": "pubmed.15537541",
        "abstract": "",
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        "title": "The roles of CARMA1, Bcl10, and MALT1 in antigen receptor signaling.",
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        "authors": "Lin X, Wang D",
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                "protein_name": "26S proteasome non-ATPase regulatory subunit 13",
                "gene_name": "PSMD13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q969T4-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 E3",
                "gene_name": "UBE2E3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P51665-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 7",
                "gene_name": "PSMD7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13309-1",
                "protein_name": "S-phase kinase-associated protein 2",
                "gene_name": "SKP2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7Z7E8-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 Q1",
                "gene_name": "UBE2Q1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5U5Q3-1",
                "protein_name": "RNA-binding E3 ubiquitin-protein ligase MEX3C",
                "gene_name": "MEX3C",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96F44-1",
                "protein_name": "E3 ubiquitin-protein ligase TRIM11",
                "gene_name": "TRIM11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96AX9-1",
                "protein_name": "E3 ubiquitin-protein ligase MIB2",
                "gene_name": "MIB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28074-1",
                "protein_name": "Proteasome subunit beta type-5",
                "gene_name": "PSMB5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P35998-1",
                "protein_name": "26S proteasome regulatory subunit 7",
                "gene_name": "PSMC2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P43686-1",
                "protein_name": "26S proteasome regulatory subunit 6B",
                "gene_name": "PSMC4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99436-1",
                "protein_name": "Proteasome subunit beta type-7",
                "gene_name": "PSMB7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NVW2-1",
                "protein_name": "E3 ubiquitin-protein ligase RLIM",
                "gene_name": "RLIM",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q63HN8-3",
                "protein_name": "E3 ubiquitin-protein ligase RNF213",
                "gene_name": "RNF213",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5VTB9-1",
                "protein_name": "E3 ubiquitin-protein ligase RNF220",
                "gene_name": "RNF220",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6ZMZ0-1",
                "protein_name": "E3 ubiquitin-protein ligase RNF19B",
                "gene_name": "RNF19B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5XUX0-1",
                "protein_name": "F-box only protein 31",
                "gene_name": "FBXO31",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9C0C9-1",
                "protein_name": "(E3-independent) E2 ubiquitin-conjugating enzyme",
                "gene_name": "UBE2O",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15370-1",
                "protein_name": "Elongin-B",
                "gene_name": "ELOB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61077-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 D3",
                "gene_name": "UBE2D3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P51668-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 D1",
                "gene_name": "UBE2D1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXI3-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 10",
                "gene_name": "ASB10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13200-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 2",
                "gene_name": "PSMD2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXK1-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 15",
                "gene_name": "ASB15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H765-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 8",
                "gene_name": "ASB8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y576-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 1",
                "gene_name": "ASB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96NS5-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 16",
                "gene_name": "ASB16",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXH4-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 11",
                "gene_name": "ASB11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXJ9-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 17",
                "gene_name": "ASB17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXK3-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 13",
                "gene_name": "ASB13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXK4-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 12",
                "gene_name": "ASB12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NWX5-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 6",
                "gene_name": "ASB6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y575-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 3",
                "gene_name": "ASB3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96LR5-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 E2",
                "gene_name": "UBE2E2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O95352-1",
                "protein_name": "Ubiquitin-like modifier-activating enzyme ATG7",
                "gene_name": "ATG7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7Z419-1",
                "protein_name": "E3 ubiquitin-protein ligase RNF144B",
                "gene_name": "RNF144B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BV68-1",
                "protein_name": "E3 ubiquitin-protein ligase RNF126",
                "gene_name": "RNF126",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96J02-1",
                "protein_name": "E3 ubiquitin-protein ligase Itchy homolog",
                "gene_name": "ITCH",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62333-1",
                "protein_name": "26S proteasome regulatory subunit 10B",
                "gene_name": "PSMC6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WWX0-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 5",
                "gene_name": "ASB5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96DX5-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 9",
                "gene_name": "ASB9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43242-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 3",
                "gene_name": "PSMD3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q969H0-1",
                "protein_name": "F-box/WD repeat-containing protein 7",
                "gene_name": "FBXW7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q969Q1-1",
                "protein_name": "E3 ubiquitin-protein ligase TRIM63",
                "gene_name": "TRIM63",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WY64-1",
                "protein_name": "E3 ubiquitin-protein ligase MYLIP",
                "gene_name": "MYLIP",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q53GT1-1",
                "protein_name": "Kelch-like protein 22",
                "gene_name": "KLHL22",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y4B6-1",
                "protein_name": "DDB1- and CUL4-associated factor 1",
                "gene_name": "DCAF1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O60662-1",
                "protein_name": "Kelch-like protein 41",
                "gene_name": "KLHL41",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6Q0C0-1",
                "protein_name": "E3 ubiquitin-protein ligase TRAF7",
                "gene_name": "TRAF7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9P2J3-1",
                "protein_name": "Kelch-like protein 9",
                "gene_name": "KLHL9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6UWE0-1",
                "protein_name": "E3 ubiquitin-protein ligase LRSAM1",
                "gene_name": "LRSAM1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WWI1-1",
                "protein_name": "LIM domain only protein 7",
                "gene_name": "LMO7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NQ86-1",
                "protein_name": "E3 ubiquitin-protein ligase TRIM36",
                "gene_name": "TRIM36",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NVR0-1",
                "protein_name": "Kelch-like protein 11",
                "gene_name": "KLHL11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9P2N7-1",
                "protein_name": "Kelch-like protein 13",
                "gene_name": "KLHL13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49721-1",
                "protein_name": "Proteasome subunit beta type-2",
                "gene_name": "PSMB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P20618-1",
                "protein_name": "Proteasome subunit beta type-1",
                "gene_name": "PSMB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43255-1",
                "protein_name": "E3 ubiquitin-protein ligase SIAH2",
                "gene_name": "SIAH2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96PQ7-1",
                "protein_name": "Kelch-like protein 5",
                "gene_name": "KLHL5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96BH1-1",
                "protein_name": "E3 ubiquitin-protein ligase RNF25",
                "gene_name": "RNF25",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y6I7-1",
                "protein_name": "WD repeat and SOCS box-containing protein 1",
                "gene_name": "WSB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q14999-1",
                "protein_name": "Cullin-7",
                "gene_name": "CUL7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49427-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 R1",
                "gene_name": "CDC34",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62877-1",
                "protein_name": "E3 ubiquitin-protein ligase RBX1",
                "gene_name": "RBX1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61081-1",
                "protein_name": "NEDD8-conjugating enzyme Ubc12",
                "gene_name": "UBE2M",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28070-1",
                "protein_name": "Proteasome subunit beta type-4",
                "gene_name": "PSMB4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9GZZ9-1",
                "protein_name": "Ubiquitin-like modifier-activating enzyme 5",
                "gene_name": "UBA5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86V97-1",
                "protein_name": "Kelch repeat and BTB domain-containing protein 6",
                "gene_name": "KBTBD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WVZ9-1",
                "protein_name": "Kelch repeat and BTB domain-containing protein 7",
                "gene_name": "KBTBD7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62256-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 H",
                "gene_name": "UBE2H",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P41226-1",
                "protein_name": "Ubiquitin-like modifier-activating enzyme 7",
                "gene_name": "UBA7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q14139-1",
                "protein_name": "Ubiquitin conjugation factor E4 A",
                "gene_name": "UBE4A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96B02-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 W",
                "gene_name": "UBE2W",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9C037-1",
                "protein_name": "E3 ubiquitin-protein ligase TRIM4",
                "gene_name": "TRIM4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P29144-1",
                "protein_name": "Tripeptidyl-peptidase 2",
                "gene_name": "TPP2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13618-1",
                "protein_name": "Cullin-3",
                "gene_name": "CUL3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25786-1",
                "protein_name": "Proteasome subunit alpha type-1",
                "gene_name": "PSMA1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q17RB8-1",
                "protein_name": "LON peptidase N-terminal domain and RING finger protein 1",
                "gene_name": "LONRF1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q16763-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 S",
                "gene_name": "UBE2S",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P40337-1",
                "protein_name": "von Hippel-Lindau disease tumor suppressor",
                "gene_name": "VHL",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86Y13-1",
                "protein_name": "E3 ubiquitin-protein ligase DZIP3",
                "gene_name": "DZIP3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96BD6-1",
                "protein_name": "SPRY domain-containing SOCS box protein 1",
                "gene_name": "SPSB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BS18-1",
                "protein_name": "Anaphase-promoting complex subunit 13",
                "gene_name": "ANAPC13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P17980-1",
                "protein_name": "26S proteasome regulatory subunit 6A",
                "gene_name": "PSMC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99619-1",
                "protein_name": "SPRY domain-containing SOCS box protein 2",
                "gene_name": "SPSB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UM13-1",
                "protein_name": "Anaphase-promoting complex subunit 10",
                "gene_name": "ANAPC10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TBB1-1",
                "protein_name": "E3 ubiquitin-protein ligase LNX",
                "gene_name": "LNX1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WV44-1",
                "protein_name": "E3 ubiquitin-protein ligase TRIM41",
                "gene_name": "TRIM41",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UJX6-1",
                "protein_name": "Anaphase-promoting complex subunit 2",
                "gene_name": "ANAPC2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NC69-1",
                "protein_name": "BTB/POZ domain-containing protein KCTD6",
                "gene_name": "KCTD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UJX2-1",
                "protein_name": "Cell division cycle protein 23 homolog",
                "gene_name": "CDC23",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96PM5-1",
                "protein_name": "RING finger and CHY zinc finger domain-containing protein 1",
                "gene_name": "RCHY1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NYG5-1",
                "protein_name": "Anaphase-promoting complex subunit 11",
                "gene_name": "ANAPC11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y297-1",
                "protein_name": "F-box/WD repeat-containing protein 1A",
                "gene_name": "BTRC",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O60260-1",
                "protein_name": "E3 ubiquitin-protein ligase parkin",
                "gene_name": "PRKN",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKB1-1",
                "protein_name": "F-box/WD repeat-containing protein 11",
                "gene_name": "FBXW11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9C026-1",
                "protein_name": "E3 ubiquitin-protein ligase TRIM9",
                "gene_name": "TRIM9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UBS8-1",
                "protein_name": "E3 ubiquitin-protein ligase RNF14",
                "gene_name": "RNF14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P30260-1",
                "protein_name": "Cell division cycle protein 27 homolog",
                "gene_name": "CDC27",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25788-1",
                "protein_name": "Proteasome subunit alpha type-3",
                "gene_name": "PSMA3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H0M0-1",
                "protein_name": "NEDD4-like E3 ubiquitin-protein ligase WWP1",
                "gene_name": "WWP1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UH77-1",
                "protein_name": "Kelch-like protein 3",
                "gene_name": "KLHL3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q969P5-1",
                "protein_name": "F-box only protein 32",
                "gene_name": "FBXO32",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y3I1-1",
                "protein_name": "F-box only protein 7",
                "gene_name": "FBXO7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9HCE7-1",
                "protein_name": "E3 ubiquitin-protein ligase SMURF1",
                "gene_name": "SMURF1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H469-1",
                "protein_name": "F-box/LRR-repeat protein 15",
                "gene_name": "FBXL15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96CD0-1",
                "protein_name": "F-box/LRR-repeat protein 8",
                "gene_name": "FBXL8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NEE6-1",
                "protein_name": "F-box and leucine-rich repeat protein 13",
                "gene_name": "FBXL13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKT7-1",
                "protein_name": "F-box/LRR-repeat protein 3",
                "gene_name": "FBXL3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96EF6-1",
                "protein_name": "F-box only protein 17",
                "gene_name": "FBXO17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UK22-1",
                "protein_name": "F-box only protein 2",
                "gene_name": "FBXO2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P57775-1",
                "protein_name": "F-box/WD repeat-containing protein 4",
                "gene_name": "FBXW4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N1E6-1",
                "protein_name": "F-box/LRR-repeat protein 14",
                "gene_name": "FBXL14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96ME1-4",
                "protein_name": "F-box/LRR-repeat protein 18",
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                "protein_name": "E3 ubiquitin-protein ligase CHIP",
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        ],
        "species": [
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                "name": "Homo sapiens",
                "taxid": 9606,
                "evidence": [
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                        "database": "UniProtKB",
                        "id": "O14818",
                        "url": "https://www.uniprot.org/uniprotkb/O14818"
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                "common_name": "Human",
                "glygen_name": "Human",
                "reference_species": "Homo sapiens [9606]"
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        ],
        "record_id": "pubmed.15571818",
        "abstract": "",
        "glycosylation": [],
        "mutagenesis": [],
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        "phosphorylation": [],
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    {
        "title": "Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex.",
        "journal": "Molecular and cellular biology",
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        "authors": "Zhang DD, Lo SC, Cross JV, Templeton DJ, Hannink M",
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            {
                "uniprot_canonical_ac": "Q9P000-1",
                "protein_name": "COMM domain-containing protein 9",
                "gene_name": "COMMD9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q969H0-1",
                "protein_name": "F-box/WD repeat-containing protein 7",
                "gene_name": "FBXW7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NX08-1",
                "protein_name": "COMM domain-containing protein 8",
                "gene_name": "COMMD8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9GZQ3-1",
                "protein_name": "COMM domain-containing protein 5",
                "gene_name": "COMMD5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5H9S7-1",
                "protein_name": "DDB1- and CUL4-associated factor 17",
                "gene_name": "DCAF17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61962-1",
                "protein_name": "DDB1- and CUL4-associated factor 7",
                "gene_name": "DCAF7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WV16-1",
                "protein_name": "DDB1- and CUL4-associated factor 4",
                "gene_name": "DCAF4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q53GT1-1",
                "protein_name": "Kelch-like protein 22",
                "gene_name": "KLHL22",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5QP82-1",
                "protein_name": "DDB1- and CUL4-associated factor 10",
                "gene_name": "DCAF10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O60662-1",
                "protein_name": "Kelch-like protein 41",
                "gene_name": "KLHL41",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9P2J3-1",
                "protein_name": "Kelch-like protein 9",
                "gene_name": "KLHL9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WWI1-1",
                "protein_name": "LIM domain only protein 7",
                "gene_name": "LMO7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NVR0-1",
                "protein_name": "Kelch-like protein 11",
                "gene_name": "KLHL11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9P2N7-1",
                "protein_name": "Kelch-like protein 13",
                "gene_name": "KLHL13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49721-1",
                "protein_name": "Proteasome subunit beta type-2",
                "gene_name": "PSMB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P20618-1",
                "protein_name": "Proteasome subunit beta type-1",
                "gene_name": "PSMB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15205-1",
                "protein_name": "Ubiquitin D",
                "gene_name": "UBD",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q16236-1",
                "protein_name": "Nuclear factor erythroid 2-related factor 2",
                "gene_name": "NFE2L2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96PQ7-1",
                "protein_name": "Kelch-like protein 5",
                "gene_name": "KLHL5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P15374-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase isozyme L3",
                "gene_name": "UCHL3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NYS7-1",
                "protein_name": "WD repeat and SOCS box-containing protein 2",
                "gene_name": "WSB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y6I7-1",
                "protein_name": "WD repeat and SOCS box-containing protein 1",
                "gene_name": "WSB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H9Q2-1",
                "protein_name": "COP9 signalosome complex subunit 7b",
                "gene_name": "COPS7B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92466-1",
                "protein_name": "DNA damage-binding protein 2",
                "gene_name": "DDB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q14999-1",
                "protein_name": "Cullin-7",
                "gene_name": "CUL7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O94888-1",
                "protein_name": "UBX domain-containing protein 7",
                "gene_name": "UBXN7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13098-4",
                "protein_name": "COP9 signalosome complex subunit 1",
                "gene_name": "GPS1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BT78-1",
                "protein_name": "COP9 signalosome complex subunit 4",
                "gene_name": "COPS4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62877-1",
                "protein_name": "E3 ubiquitin-protein ligase RBX1",
                "gene_name": "RBX1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15843-1",
                "protein_name": "Ubiquitin-like protein NEDD8",
                "gene_name": "NEDD8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61081-1",
                "protein_name": "NEDD8-conjugating enzyme Ubc12",
                "gene_name": "UBE2M",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28070-1",
                "protein_name": "Proteasome subunit beta type-4",
                "gene_name": "PSMB4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86V97-1",
                "protein_name": "Kelch repeat and BTB domain-containing protein 6",
                "gene_name": "KBTBD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WVZ9-1",
                "protein_name": "Kelch repeat and BTB domain-containing protein 7",
                "gene_name": "KBTBD7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NRJ4-1",
                "protein_name": "Tubby-related protein 4",
                "gene_name": "TULP4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61964-1",
                "protein_name": "WD repeat-containing protein 5",
                "gene_name": "WDR5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P55072-1",
                "protein_name": "Transitional endoplasmic reticulum ATPase",
                "gene_name": "VCP",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13618-1",
                "protein_name": "Cullin-3",
                "gene_name": "CUL3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25786-1",
                "protein_name": "Proteasome subunit alpha type-1",
                "gene_name": "PSMA1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NHY2-1",
                "protein_name": "E3 ubiquitin-protein ligase COP1",
                "gene_name": "COP1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7L5N1-1",
                "protein_name": "COP9 signalosome complex subunit 6",
                "gene_name": "COPS6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P40337-1",
                "protein_name": "von Hippel-Lindau disease tumor suppressor",
                "gene_name": "VHL",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5TAQ9-1",
                "protein_name": "DDB1- and CUL4-associated factor 8",
                "gene_name": "DCAF8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96BD6-1",
                "protein_name": "SPRY domain-containing SOCS box protein 1",
                "gene_name": "SPSB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5JTC6-1",
                "protein_name": "APC membrane recruitment protein 1",
                "gene_name": "AMER1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P17980-1",
                "protein_name": "26S proteasome regulatory subunit 6A",
                "gene_name": "PSMC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99619-1",
                "protein_name": "SPRY domain-containing SOCS box protein 2",
                "gene_name": "SPSB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O60826-1",
                "protein_name": "Coiled-coil domain-containing protein 22",
                "gene_name": "CCDC22",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NC69-1",
                "protein_name": "BTB/POZ domain-containing protein KCTD6",
                "gene_name": "KCTD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y297-1",
                "protein_name": "F-box/WD repeat-containing protein 1A",
                "gene_name": "BTRC",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O14544-1",
                "protein_name": "Suppressor of cytokine signaling 6",
                "gene_name": "SOCS6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKB1-1",
                "protein_name": "F-box/WD repeat-containing protein 11",
                "gene_name": "FBXW11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25788-1",
                "protein_name": "Proteasome subunit alpha type-3",
                "gene_name": "PSMA3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8IWE4-1",
                "protein_name": "DCN1-like protein 3",
                "gene_name": "DCUN1D3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UH77-1",
                "protein_name": "Kelch-like protein 3",
                "gene_name": "KLHL3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q969P5-1",
                "protein_name": "F-box only protein 32",
                "gene_name": "FBXO32",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y3I1-1",
                "protein_name": "F-box only protein 7",
                "gene_name": "FBXO7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H469-1",
                "protein_name": "F-box/LRR-repeat protein 15",
                "gene_name": "FBXL15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96CD0-1",
                "protein_name": "F-box/LRR-repeat protein 8",
                "gene_name": "FBXL8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NEE6-1",
                "protein_name": "F-box and leucine-rich repeat protein 13",
                "gene_name": "FBXL13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKT7-1",
                "protein_name": "F-box/LRR-repeat protein 3",
                "gene_name": "FBXL3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96EF6-1",
                "protein_name": "F-box only protein 17",
                "gene_name": "FBXO17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UK22-1",
                "protein_name": "F-box only protein 2",
                "gene_name": "FBXO2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P57775-1",
                "protein_name": "F-box/WD repeat-containing protein 4",
                "gene_name": "FBXW4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N1E6-1",
                "protein_name": "F-box/LRR-repeat protein 14",
                "gene_name": "FBXL14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96ME1-4",
                "protein_name": "F-box/LRR-repeat protein 18",
                "gene_name": "FBXL18",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UJT9-1",
                "protein_name": "F-box/LRR-repeat protein 7",
                "gene_name": "FBXL7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKT6-1",
                "protein_name": "Putative F-box/LRR-repeat protein 21",
                "gene_name": "FBXL21P",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O14543-1",
                "protein_name": "Suppressor of cytokine signaling 3",
                "gene_name": "SOCS3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N5D0-1",
                "protein_name": "WD and tetratricopeptide repeats protein 1",
                "gene_name": "WDTC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13501-1",
                "protein_name": "Sequestosome-1",
                "gene_name": "SQSTM1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q969U6-1",
                "protein_name": "F-box/WD repeat-containing protein 5",
                "gene_name": "FBXW5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86XK2-1",
                "protein_name": "F-box only protein 11",
                "gene_name": "FBXO11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P60900-1",
                "protein_name": "Proteasome subunit alpha type-6",
                "gene_name": "PSMA6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62979-1",
                "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein",
                "gene_name": "RPS27A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86YC2-1",
                "protein_name": "Partner and localizer of BRCA2",
                "gene_name": "PALB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H4M3-1",
                "protein_name": "F-box only protein 44",
                "gene_name": "FBXO44",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96KE9-3",
                "protein_name": "BTB/POZ domain-containing protein 6",
                "gene_name": "BTBD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92905-1",
                "protein_name": "COP9 signalosome complex subunit 5",
                "gene_name": "COPS5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13617-1",
                "protein_name": "Cullin-2",
                "gene_name": "CUL2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13619-1",
                "protein_name": "Cullin-4A",
                "gene_name": "CUL4A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86VP6-1",
                "protein_name": "Cullin-associated NEDD8-dissociated protein 1",
                "gene_name": "CAND1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62837-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 D2",
                "gene_name": "UBE2D2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13620-2",
                "protein_name": "Cullin-4B",
                "gene_name": "CUL4B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H0C5-1",
                "protein_name": "BTB/POZ domain-containing protein 1",
                "gene_name": "BTBD1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NXF7-1",
                "protein_name": "DDB1- and CUL4-associated factor 16",
                "gene_name": "DCAF16",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y2N7-1",
                "protein_name": "Hypoxia-inducible factor 3-alpha",
                "gene_name": "HIF3A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P48556-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 8",
                "gene_name": "PSMD8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15008-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 6",
                "gene_name": "PSMD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28072-1",
                "protein_name": "Proteasome subunit beta type-6",
                "gene_name": "PSMB6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O00232-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 12",
                "gene_name": "PSMD12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25787-1",
                "protein_name": "Proteasome subunit alpha type-2",
                "gene_name": "PSMA2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28066-1",
                "protein_name": "Proteasome subunit alpha type-5",
                "gene_name": "PSMA5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NCQ5-1",
                "protein_name": "F-box only protein 15",
                "gene_name": "FBXO15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UK96-1",
                "protein_name": "F-box only protein 10",
                "gene_name": "FBXO10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TB52-1",
                "protein_name": "F-box only protein 30",
                "gene_name": "FBXO30",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96JP0-1",
                "protein_name": "Protein fem-1 homolog C",
                "gene_name": "FEM1C",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UH90-1",
                "protein_name": "F-box only protein 40",
                "gene_name": "FBXO40",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q969M7-1",
                "protein_name": "NEDD8-conjugating enzyme UBE2F",
                "gene_name": "UBE2F-SCLY; UBE2F",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96LD8-1",
                "protein_name": "Sentrin-specific protease 8",
                "gene_name": "SENP8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13564-1",
                "protein_name": "NEDD8-activating enzyme E1 regulatory subunit",
                "gene_name": "NAE1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O95198-1",
                "protein_name": "Kelch-like protein 2",
                "gene_name": "KLHL2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P38936-1",
                "protein_name": "Cyclin-dependent kinase inhibitor 1",
                "gene_name": "CDKN1A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NXK8-1",
                "protein_name": "F-box/LRR-repeat protein 12",
                "gene_name": "FBXL12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0CG47-1",
                "protein_name": "Polyubiquitin-B",
                "gene_name": "UBB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKT8-1",
                "protein_name": "F-box/WD repeat-containing protein 2",
                "gene_name": "FBXW2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TEB1-1",
                "protein_name": "DDB1- and CUL4-associated factor 11",
                "gene_name": "DCAF11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TB72-1",
                "protein_name": "Pumilio homolog 2",
                "gene_name": "PUM2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BTE7-1",
                "protein_name": "DCN1-like protein 5",
                "gene_name": "DCUN1D5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q58WW2-1",
                "protein_name": "DDB1- and CUL4-associated factor 6",
                "gene_name": "DCAF6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6PH85-1",
                "protein_name": "DCN1-like protein 2",
                "gene_name": "DCUN1D2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92564-1",
                "protein_name": "DCN1-like protein 4",
                "gene_name": "DCUN1D4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96JK2-1",
                "protein_name": "DDB1- and CUL4-associated factor 5",
                "gene_name": "DCAF5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62987-1",
                "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein",
                "gene_name": "UBA52",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NZJ0-1",
                "protein_name": "Denticleless protein homolog",
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                "tax_name": "Human"
            },
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                "tax_name": "Human"
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                "protein_name": "Endothelial PAS domain-containing protein 1",
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            },
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                "uniprot_canonical_ac": "Q9BW61-1",
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                "protein_name": "26S proteasome regulatory subunit 10B",
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                "protein_name": "COP9 signalosome complex subunit 2",
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                "protein_name": "26S proteasome non-ATPase regulatory subunit 3",
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                "uniprot_canonical_ac": "Q9H0W5-1",
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                "tax_name": "Human"
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                "uniprot_canonical_ac": "Q9NX08-1",
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                "protein_name": "COMM domain-containing protein 5",
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                "tax_name": "Human"
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                "uniprot_canonical_ac": "Q53GT1-1",
                "protein_name": "Kelch-like protein 22",
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                "uniprot_canonical_ac": "Q5QP82-1",
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                "tax_name": "Human"
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                "uniprot_canonical_ac": "O60662-1",
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                "tax_name": "Human"
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                "protein_name": "Kelch-like protein 9",
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                "protein_name": "LIM domain only protein 7",
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                "protein_name": "Kelch-like protein 11",
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                "protein_name": "Proteasome subunit beta type-2",
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                "protein_name": "Ubiquitin D",
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                "protein_name": "Nuclear factor erythroid 2-related factor 2",
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                "protein_name": "Ubiquitin carboxyl-terminal hydrolase isozyme L3",
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                "protein_name": "E3 ubiquitin-protein ligase RBX1",
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                "protein_name": "WD repeat-containing protein 5",
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                "protein_name": "Transitional endoplasmic reticulum ATPase",
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                "protein_name": "E3 ubiquitin-protein ligase COP1",
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                "uniprot_canonical_ac": "P40337-1",
                "protein_name": "von Hippel-Lindau disease tumor suppressor",
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                "uniprot_canonical_ac": "Q5TAQ9-1",
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                "tax_name": "Human"
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                "protein_name": "SPRY domain-containing SOCS box protein 1",
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            {
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                "protein_name": "APC membrane recruitment protein 1",
                "gene_name": "AMER1",
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                "protein_name": "26S proteasome regulatory subunit 6A",
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                "uniprot_canonical_ac": "Q99619-1",
                "protein_name": "SPRY domain-containing SOCS box protein 2",
                "gene_name": "SPSB2",
                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "O60826-1",
                "protein_name": "Coiled-coil domain-containing protein 22",
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                "uniprot_canonical_ac": "Q8NC69-1",
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                "tax_name": "Human"
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                "uniprot_canonical_ac": "Q9Y297-1",
                "protein_name": "F-box/WD repeat-containing protein 1A",
                "gene_name": "BTRC",
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                "protein_name": "Suppressor of cytokine signaling 6",
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                "tax_name": "Human"
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                "uniprot_canonical_ac": "Q9UKB1-1",
                "protein_name": "F-box/WD repeat-containing protein 11",
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                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "P25788-1",
                "protein_name": "Proteasome subunit alpha type-3",
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                "tax_name": "Human"
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                "uniprot_canonical_ac": "Q8IWE4-1",
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                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "Q9UH77-1",
                "protein_name": "Kelch-like protein 3",
                "gene_name": "KLHL3",
                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "Q969P5-1",
                "protein_name": "F-box only protein 32",
                "gene_name": "FBXO32",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y3I1-1",
                "protein_name": "F-box only protein 7",
                "gene_name": "FBXO7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H469-1",
                "protein_name": "F-box/LRR-repeat protein 15",
                "gene_name": "FBXL15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96CD0-1",
                "protein_name": "F-box/LRR-repeat protein 8",
                "gene_name": "FBXL8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NEE6-1",
                "protein_name": "F-box and leucine-rich repeat protein 13",
                "gene_name": "FBXL13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKT7-1",
                "protein_name": "F-box/LRR-repeat protein 3",
                "gene_name": "FBXL3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96EF6-1",
                "protein_name": "F-box only protein 17",
                "gene_name": "FBXO17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UK22-1",
                "protein_name": "F-box only protein 2",
                "gene_name": "FBXO2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P57775-1",
                "protein_name": "F-box/WD repeat-containing protein 4",
                "gene_name": "FBXW4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N1E6-1",
                "protein_name": "F-box/LRR-repeat protein 14",
                "gene_name": "FBXL14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96ME1-4",
                "protein_name": "F-box/LRR-repeat protein 18",
                "gene_name": "FBXL18",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UJT9-1",
                "protein_name": "F-box/LRR-repeat protein 7",
                "gene_name": "FBXL7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKT6-1",
                "protein_name": "Putative F-box/LRR-repeat protein 21",
                "gene_name": "FBXL21P",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O14543-1",
                "protein_name": "Suppressor of cytokine signaling 3",
                "gene_name": "SOCS3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N5D0-1",
                "protein_name": "WD and tetratricopeptide repeats protein 1",
                "gene_name": "WDTC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13501-1",
                "protein_name": "Sequestosome-1",
                "gene_name": "SQSTM1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q969U6-1",
                "protein_name": "F-box/WD repeat-containing protein 5",
                "gene_name": "FBXW5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86XK2-1",
                "protein_name": "F-box only protein 11",
                "gene_name": "FBXO11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P60900-1",
                "protein_name": "Proteasome subunit alpha type-6",
                "gene_name": "PSMA6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62979-1",
                "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein",
                "gene_name": "RPS27A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86YC2-1",
                "protein_name": "Partner and localizer of BRCA2",
                "gene_name": "PALB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H4M3-1",
                "protein_name": "F-box only protein 44",
                "gene_name": "FBXO44",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96KE9-3",
                "protein_name": "BTB/POZ domain-containing protein 6",
                "gene_name": "BTBD6",
                "tax_name": "Human"
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    {
        "title": "Activation of MK5/PRAK by the atypical MAP kinase ERK3 defines a novel signal transduction pathway.",
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    {
        "title": "BTB protein Keap1 targets antioxidant transcription factor Nrf2 for ubiquitination by the Cullin 3-Roc1 ligase.",
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                "gene_name": "PSMB5",
                "tax_name": "Human"
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                "tax_name": "Human"
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                "gene_name": "PSMC4",
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                "protein_name": "Proteasome subunit beta type-7",
                "gene_name": "PSMB7",
                "tax_name": "Human"
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                "protein_name": "Baculoviral IAP repeat-containing protein 5",
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                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5XUX0-1",
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                "gene_name": "FBXO31",
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            },
            {
                "uniprot_canonical_ac": "Q15370-1",
                "protein_name": "Elongin-B",
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            },
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                "protein_name": "Ubiquitin-conjugating enzyme E2 D3",
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                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P51668-1",
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                "gene_name": "UBE2D1",
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            {
                "uniprot_canonical_ac": "O14508-1",
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                "protein_name": "DNA damage-binding protein 1",
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                "tax_name": "Human"
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            {
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                "protein_name": "Ankyrin repeat and SOCS box protein 10",
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                "tax_name": "Human"
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            {
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                "protein_name": "26S proteasome non-ATPase regulatory subunit 2",
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                "tax_name": "Human"
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            {
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                "tax_name": "Human"
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                "uniprot_canonical_ac": "Q8WXK1-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 15",
                "gene_name": "ASB15",
                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "Q9H765-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 8",
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                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y576-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 1",
                "gene_name": "ASB1",
                "tax_name": "Human"
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                "uniprot_canonical_ac": "Q96NS5-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 16",
                "gene_name": "ASB16",
                "tax_name": "Human"
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                "uniprot_canonical_ac": "Q8WXH4-1",
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                "tax_name": "Human"
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                "uniprot_canonical_ac": "Q8WXJ9-1",
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                "tax_name": "Human"
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                "protein_name": "Ankyrin repeat and SOCS box protein 13",
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                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "Q8WXK4-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 12",
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                "gene_name": "ASB6",
                "tax_name": "Human"
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                "protein_name": "Ankyrin repeat and SOCS box protein 3",
                "gene_name": "ASB3",
                "tax_name": "Human"
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                "protein_name": "Endothelial PAS domain-containing protein 1",
                "gene_name": "EPAS1",
                "tax_name": "Human"
            },
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                "uniprot_canonical_ac": "Q9BW61-1",
                "protein_name": "DET1- and DDB1-associated protein 1",
                "gene_name": "DDA1",
                "tax_name": "Human"
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                "uniprot_canonical_ac": "Q8N668-1",
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                "protein_name": "26S proteasome regulatory subunit 10B",
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                "tax_name": "Human"
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                "protein_name": "Ankyrin repeat and SOCS box protein 5",
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                "uniprot_canonical_ac": "Q96DX5-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 9",
                "gene_name": "ASB9",
                "tax_name": "Human"
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            {
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                "protein_name": "COMM domain-containing protein 3",
                "gene_name": "COMMD3",
                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "P61201-1",
                "protein_name": "COP9 signalosome complex subunit 2",
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                "tax_name": "Human"
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                "protein_name": "COMM domain-containing protein 6",
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                "tax_name": "Human"
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                "uniprot_canonical_ac": "Q9H0A8-1",
                "protein_name": "COMM domain-containing protein 4",
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                "tax_name": "Human"
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                "uniprot_canonical_ac": "Q9Y6G5-1",
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                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "O43242-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 3",
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                "uniprot_canonical_ac": "Q9H0W5-1",
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                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "Q86X83-1",
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                "tax_name": "Human"
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                "tax_name": "Human"
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                "uniprot_canonical_ac": "Q969H0-1",
                "protein_name": "F-box/WD repeat-containing protein 7",
                "gene_name": "FBXW7",
                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "Q9NX08-1",
                "protein_name": "COMM domain-containing protein 8",
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                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "Q9GZQ3-1",
                "protein_name": "COMM domain-containing protein 5",
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                "tax_name": "Human"
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                "uniprot_canonical_ac": "Q5H9S7-1",
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                "gene_name": "DCAF17",
                "tax_name": "Human"
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                "uniprot_canonical_ac": "P61962-1",
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                "gene_name": "DCAF7",
                "tax_name": "Human"
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                "uniprot_canonical_ac": "Q8WV16-1",
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                "gene_name": "DCAF4",
                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "Q53GT1-1",
                "protein_name": "Kelch-like protein 22",
                "gene_name": "KLHL22",
                "tax_name": "Human"
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                "uniprot_canonical_ac": "Q5QP82-1",
                "protein_name": "DDB1- and CUL4-associated factor 10",
                "gene_name": "DCAF10",
                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "O60662-1",
                "protein_name": "Kelch-like protein 41",
                "gene_name": "KLHL41",
                "tax_name": "Human"
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                "uniprot_canonical_ac": "Q9P2J3-1",
                "protein_name": "Kelch-like protein 9",
                "gene_name": "KLHL9",
                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "Q8WWI1-1",
                "protein_name": "LIM domain only protein 7",
                "gene_name": "LMO7",
                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "Q9NVR0-1",
                "protein_name": "Kelch-like protein 11",
                "gene_name": "KLHL11",
                "tax_name": "Human"
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                "uniprot_canonical_ac": "Q9P2N7-1",
                "protein_name": "Kelch-like protein 13",
                "gene_name": "KLHL13",
                "tax_name": "Human"
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                "uniprot_canonical_ac": "P49721-1",
                "protein_name": "Proteasome subunit beta type-2",
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                "tax_name": "Human"
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                "uniprot_canonical_ac": "P20618-1",
                "protein_name": "Proteasome subunit beta type-1",
                "gene_name": "PSMB1",
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                "protein_name": "Ubiquitin D",
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                "uniprot_canonical_ac": "Q16236-1",
                "protein_name": "Nuclear factor erythroid 2-related factor 2",
                "gene_name": "NFE2L2",
                "tax_name": "Human"
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                "protein_name": "Ubiquitin carboxyl-terminal hydrolase isozyme L3",
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                "uniprot_canonical_ac": "Q9NYS7-1",
                "protein_name": "WD repeat and SOCS box-containing protein 2",
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                "tax_name": "Human"
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                "uniprot_canonical_ac": "Q9Y6I7-1",
                "protein_name": "WD repeat and SOCS box-containing protein 1",
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                "tax_name": "Human"
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                "protein_name": "COP9 signalosome complex subunit 7b",
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                "protein_name": "DNA damage-binding protein 2",
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                "protein_name": "Cullin-7",
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                "tax_name": "Human"
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                "protein_name": "UBX domain-containing protein 7",
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                "protein_name": "COP9 signalosome complex subunit 1",
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                "protein_name": "COP9 signalosome complex subunit 4",
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            {
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                "protein_name": "E3 ubiquitin-protein ligase RBX1",
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                "uniprot_canonical_ac": "Q15843-1",
                "protein_name": "Ubiquitin-like protein NEDD8",
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                "uniprot_canonical_ac": "P61081-1",
                "protein_name": "NEDD8-conjugating enzyme Ubc12",
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                "uniprot_canonical_ac": "Q86V97-1",
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                "gene_name": "KBTBD6",
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                "uniprot_canonical_ac": "Q8WVZ9-1",
                "protein_name": "Kelch repeat and BTB domain-containing protein 7",
                "gene_name": "KBTBD7",
                "tax_name": "Human"
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                "uniprot_canonical_ac": "Q9NRJ4-1",
                "protein_name": "Tubby-related protein 4",
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                "tax_name": "Human"
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                "uniprot_canonical_ac": "P61964-1",
                "protein_name": "WD repeat-containing protein 5",
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                "tax_name": "Human"
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                "protein_name": "Transitional endoplasmic reticulum ATPase",
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                "tax_name": "Human"
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                "protein_name": "Cullin-3",
                "gene_name": "CUL3",
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                "uniprot_canonical_ac": "P25786-1",
                "protein_name": "Proteasome subunit alpha type-1",
                "gene_name": "PSMA1",
                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "Q8NHY2-1",
                "protein_name": "E3 ubiquitin-protein ligase COP1",
                "gene_name": "COP1",
                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "Q7L5N1-1",
                "protein_name": "COP9 signalosome complex subunit 6",
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            {
                "uniprot_canonical_ac": "P40337-1",
                "protein_name": "von Hippel-Lindau disease tumor suppressor",
                "gene_name": "VHL",
                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "Q5TAQ9-1",
                "protein_name": "DDB1- and CUL4-associated factor 8",
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                "tax_name": "Human"
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                "uniprot_canonical_ac": "Q96BD6-1",
                "protein_name": "SPRY domain-containing SOCS box protein 1",
                "gene_name": "SPSB1",
                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "Q5JTC6-1",
                "protein_name": "APC membrane recruitment protein 1",
                "gene_name": "AMER1",
                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "P17980-1",
                "protein_name": "26S proteasome regulatory subunit 6A",
                "gene_name": "PSMC3",
                "tax_name": "Human"
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                "uniprot_canonical_ac": "Q99619-1",
                "protein_name": "SPRY domain-containing SOCS box protein 2",
                "gene_name": "SPSB2",
                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "O60826-1",
                "protein_name": "Coiled-coil domain-containing protein 22",
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                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "Q8NC69-1",
                "protein_name": "BTB/POZ domain-containing protein KCTD6",
                "gene_name": "KCTD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y297-1",
                "protein_name": "F-box/WD repeat-containing protein 1A",
                "gene_name": "BTRC",
                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "O14544-1",
                "protein_name": "Suppressor of cytokine signaling 6",
                "gene_name": "SOCS6",
                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "Q9UKB1-1",
                "protein_name": "F-box/WD repeat-containing protein 11",
                "gene_name": "FBXW11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25788-1",
                "protein_name": "Proteasome subunit alpha type-3",
                "gene_name": "PSMA3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8IWE4-1",
                "protein_name": "DCN1-like protein 3",
                "gene_name": "DCUN1D3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UH77-1",
                "protein_name": "Kelch-like protein 3",
                "gene_name": "KLHL3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q969P5-1",
                "protein_name": "F-box only protein 32",
                "gene_name": "FBXO32",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y3I1-1",
                "protein_name": "F-box only protein 7",
                "gene_name": "FBXO7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H469-1",
                "protein_name": "F-box/LRR-repeat protein 15",
                "gene_name": "FBXL15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96CD0-1",
                "protein_name": "F-box/LRR-repeat protein 8",
                "gene_name": "FBXL8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NEE6-1",
                "protein_name": "F-box and leucine-rich repeat protein 13",
                "gene_name": "FBXL13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKT7-1",
                "protein_name": "F-box/LRR-repeat protein 3",
                "gene_name": "FBXL3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96EF6-1",
                "protein_name": "F-box only protein 17",
                "gene_name": "FBXO17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UK22-1",
                "protein_name": "F-box only protein 2",
                "gene_name": "FBXO2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P57775-1",
                "protein_name": "F-box/WD repeat-containing protein 4",
                "gene_name": "FBXW4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N1E6-1",
                "protein_name": "F-box/LRR-repeat protein 14",
                "gene_name": "FBXL14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96ME1-4",
                "protein_name": "F-box/LRR-repeat protein 18",
                "gene_name": "FBXL18",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UJT9-1",
                "protein_name": "F-box/LRR-repeat protein 7",
                "gene_name": "FBXL7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKT6-1",
                "protein_name": "Putative F-box/LRR-repeat protein 21",
                "gene_name": "FBXL21P",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O14543-1",
                "protein_name": "Suppressor of cytokine signaling 3",
                "gene_name": "SOCS3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N5D0-1",
                "protein_name": "WD and tetratricopeptide repeats protein 1",
                "gene_name": "WDTC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13501-1",
                "protein_name": "Sequestosome-1",
                "gene_name": "SQSTM1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q969U6-1",
                "protein_name": "F-box/WD repeat-containing protein 5",
                "gene_name": "FBXW5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86XK2-1",
                "protein_name": "F-box only protein 11",
                "gene_name": "FBXO11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P60900-1",
                "protein_name": "Proteasome subunit alpha type-6",
                "gene_name": "PSMA6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62979-1",
                "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein",
                "gene_name": "RPS27A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86YC2-1",
                "protein_name": "Partner and localizer of BRCA2",
                "gene_name": "PALB2",
                "tax_name": "Human"
            },
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